Hill et al. Comparison of stratified primary care management for low-back pain with current best practice¶
One-paragraph summary¶
The trial randomized 851 English primary-care participants with low-back pain to prognosis-stratified matched care (568) or current best practice (283). Adjusted between-group RMDQ differences favored stratified care by 1.81 points (95% CI 1.06–2.57) at four months and 1.06 (0.25–1.86) at 12 months; the intervention added 0.039 QALYs and reduced mean back-pain healthcare costs (£240.01 vs £274.40) (PMID 21963002). It established a service-delivery model, not a DDD diagnostic or disc-specific treatment.
Key findings¶
- 851 randomized participants from ten general practices.
- 2:1 allocation to stratified versus control care.
- Four-month RMDQ difference 1.81 (95% CI 1.06–2.57).
- Twelve-month RMDQ difference 1.06 (0.25–1.86).
- Additional 0.039 QALYs at 12 months.
- Mean back-pain healthcare cost £240.01 versus £274.40.
Limitations¶
- Conducted in one UK delivery system.
- Participants and clinicians could not be blinded.
- Population included back pain with or without radiculopathy, not DDD.
- Later implementation trials did not uniformly replicate benefit.
- Screening tool predicts prognosis, not pain source.
Why it matters¶
The trial showed that matching care intensity to prognostic risk could improve value. It also became a case study in why successful service models require replication in local systems.
Cited by wiki pages¶
- Epidemiology and natural history
- Conservative treatment
- Guidelines
- Clinical trials landscape