Master bibliography — uterine adenosarcoma¶

Last curated: 2026-09-01. One line per paper: citation, PMID, tags, wiki pages that cite it. The independent audit re-fetched all 66 listed PMIDs through live PubMed E-utilities on 2026-09-01; all resolved and matched their cited papers. This is a density-exempt condition (258 PubMed records in the live condition search); the bibliography is the cited set, not a padded scrape of the 258.

Companion files: guidelines/REGISTRY.md, statistics/STATISTICS.md, patient-voice/sources.md, notes/ (6 landmark notes).

Pathology, nosology, and diagnosis¶

Clement PB, Scully RE. Müllerian adenosarcoma of the uterus. A clinicopathologic analysis of ten cases of a distinctive type of müllerian mixed tumor. Cancer. 1974;34:1138-49. PMID 4371193 — tags: [landmark, original-description] — cited by: overview.md
Clement PB, Scully RE. Mullerian adenosarcoma of the uterus: a clinicopathologic analysis of 100 cases with a review of the literature. Hum Pathol. 1990;21:363-81. PMID 2156771 — tags: [landmark, natural-history, recurrent-polyps] — cited by: overview.md, pathology-and-diagnosis.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, staging-and-prognostic-factors.md, surgical-management.md, recurrence-and-surveillance.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Clement PB. Müllerian adenosarcomas of the uterus with sarcomatous overgrowth. A clinicopathological analysis of 10 cases. Am J Surg Pathol. 1989;13:28-38. PMID 2535774 — tags: [landmark, sarcomatous-overgrowth, definition] — cited by: overview.md, sarcomatous-overgrowth.md, recurrence-and-surveillance.md, red-flags-and-safety-concerns.md
Clement PB. Müllerian adenosarcomas of the uterus with sex cord-like elements. A clinicopathologic analysis of eight cases. Am J Clin Pathol. 1989;91:664-72. PMID 2543209 — tags: [sex-cord-like] — cited by: pathology-and-diagnosis.md
Clement PB, Scully RE. Endometrial stromal sarcomas of the uterus with extensive endometrioid glandular differentiation: a report of three cases. Int J Gynecol Pathol. 1992;11:163-73. PMID 1399225 — tags: [differential, ESS] — cited by: pathology-and-diagnosis.md
Zaloudek CJ, Norris HJ. Adenofibroma and adenosarcoma of the uterus: a clinicopathologic study of 35 cases. Cancer. 1981;48:354-66. PMID 6263458 — tags: [adenofibroma, mitotic-threshold] — cited by: overview.md, pathology-and-diagnosis.md, staging-and-prognostic-factors.md, recurrence-and-surveillance.md
Kaku T, et al. Adenosarcoma of the uterus: a Gynecologic Oncology Group clinicopathologic study of 31 cases. Int J Gynecol Pathol. 1992;11:75-88. PMID 1316323 — tags: [GOG, staging-laparotomy, SO-frequency] — cited by: sarcomatous-overgrowth.md, epidemiology-and-burden.md, staging-and-prognostic-factors.md, surgical-management.md, recurrence-and-surveillance.md
Gallardo A, Prat J. Mullerian adenosarcoma: a clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma. Am J Surg Pathol. 2009;33:278-88. PMID 18941402 — tags: [adenofibroma, IHC, SO] — cited by: overview.md, pathology-and-diagnosis.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, staging-and-prognostic-factors.md, surgical-management.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md
McCluggage WG. A practical approach to the diagnosis of mixed epithelial and mesenchymal tumours of the uterus. Mod Pathol. 2016;29 Suppl 1:S78-91. PMID 26715175 — tags: [WHO-2014, differential] — cited by: overview.md, pathology-and-diagnosis.md, epidemiology-and-burden.md
Pinto A, Howitt B. Uterine Adenosarcoma. Arch Pathol Lab Med. 2016;140:286-90. PMID 26927725 — tags: [review, pathology] — cited by: overview.md, pathology-and-diagnosis.md, sarcomatous-overgrowth.md
D'Angelo E, Prat J. Pathology of mixed Müllerian tumours. Best Pract Res Clin Obstet Gynaecol. 2011;25:705-18. PMID 21742560 — tags: [mixed-mullerian, review] — cited by: pathology-and-diagnosis.md
D'Angelo E, Prat J. Uterine sarcomas: a review. Gynecol Oncol. 2010;116:131-9. PMID 19853898 — tags: [uterine-sarcoma, FIGO, review] — cited by: epidemiology-and-burden.md, staging-and-prognostic-factors.md
Howitt BE, et al. Uterine polyps with features overlapping with those of Müllerian adenosarcoma: a clinicopathologic analysis of 29 cases emphasizing their likely benign nature. Am J Surg Pathol. 2015;39:116-26. PMID 25118811 — tags: [atypical-polyps, differential] — cited by: overview.md, pathology-and-diagnosis.md, clinical-presentation-and-imaging.md, red-flags-and-safety-concerns.md
Chapel DB, et al. Atypical uterine polyps show morphologic and molecular overlap with mullerian adenosarcoma but follow a benign clinical course. Mod Pathol. 2022;35:106-116. PMID 34675347 — tags: [atypical-polyps, copy-number] — cited by: overview.md, pathology-and-diagnosis.md, molecular-and-genomic-features.md, clinical-presentation-and-imaging.md, red-flags-and-safety-concerns.md
Strickland KC, et al. Clinicopathological and immunohistochemical features of uterine adenomyomatous polyps. Hum Pathol. 2019;84:239-245. PMID 30339971 — tags: [differential] — cited by: pathology-and-diagnosis.md

Sarcomatous overgrowth, high-grade stroma, and prognosis¶

Carroll A, et al. Uterine adenosarcoma: an analysis on management, outcomes, and risk factors for recurrence. Gynecol Oncol. 2014;135:455-61. PMID 25449308 — tags: [landmark, SO, adjuvant, multivariable] — cited by: overview.md, sarcomatous-overgrowth.md, staging-and-prognostic-factors.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md, guidelines.md, clinical-trials-landscape.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Tanner EJ, et al. Management of uterine adenosarcomas with and without sarcomatous overgrowth. Gynecol Oncol. 2013;129:140-4. PMID 23283300 — tags: [SO, MSK, adjuvant] — cited by: overview.md, sarcomatous-overgrowth.md, surgical-management.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md
Nathenson MJ, Conley AP. Prognostic factors for uterine adenosarcoma: a review. Expert Rev Anticancer Ther. 2018;18:1093-1100. PMID 30169984 — tags: [review, prognostic-factors] — cited by: overview.md, staging-and-prognostic-factors.md, adjuvant-and-systemic-therapy.md, guidelines.md
Nathenson MJ, et al. Uterine Adenosarcoma: a Review. Curr Oncol Rep. 2016;18:68. PMID 27718181 — tags: [review, 5-percent, SO-recurrence] — cited by: overview.md, pathology-and-diagnosis.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, surgical-management.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md, guidelines.md
Nathenson MJ, et al. The Importance of Lymphovascular Invasion in Uterine Adenosarcomas. Int J Gynecol Cancer. 2018;28:1297-1310. PMID 30044322 — tags: [landmark, LVSI, radiation] — cited by: overview.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, staging-and-prognostic-factors.md, surgical-management.md, adjuvant-and-systemic-therapy.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Hodgson A, et al. High-grade Müllerian Adenosarcoma: Genomic and Clinicopathologic Characterization of a Distinct Neoplasm With Prevalent TP53 Pathway Alterations and Aggressive Behavior. Am J Surg Pathol. 2017;41:1513-1522. PMID 28834809 — tags: [high-grade, TP53] — cited by: pathology-and-diagnosis.md, sarcomatous-overgrowth.md, molecular-and-genomic-features.md, red-flags-and-safety-concerns.md
Yuan Z, et al. Uterine Adenosarcoma: A Retrospective 12-Year Single-Center Study. Front Oncol. 2019;9:237. PMID 31139558 — tags: [stalk, LVSI, fertility-sparing, cervix] — cited by: sarcomatous-overgrowth.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, staging-and-prognostic-factors.md, surgical-management.md, patient-experience-and-advocacy.md
Li JY, et al. Clinicopathologic characteristics and oncologic outcomes in adenosarcoma of gynecologic sites. Gynecol Oncol Rep. 2022;39:100913. PMID 35005157 — tags: [ovarian-preservation, RFS] — cited by: overview.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, staging-and-prognostic-factors.md, surgical-management.md, adjuvant-and-systemic-therapy.md, guidelines.md

Molecular and genomic¶

Howitt BE, et al. Targeted genomic analysis of Müllerian adenosarcoma. J Pathol. 2015;235:37-49. PMID 25231023 — tags: [landmark, NGS, MDM2, CDK4, CNV] — cited by: overview.md, pathology-and-diagnosis.md, sarcomatous-overgrowth.md, molecular-and-genomic-features.md, clinical-trials-landscape.md
Howitt BE, et al. Involvement of Chromosome 8 in Müllerian Adenosarcoma. Int J Gynecol Pathol. 2017;36:24-30. PMID 26974998 — tags: [cytogenetics, chr8] — cited by: molecular-and-genomic-features.md
Geyer FC, et al. Genetic analysis of uterine adenosarcomas and phyllodes tumors of the breast. Mol Oncol. 2017;11:913-926. PMID 28267263 — tags: [TERT, MDM2, phyllodes] — cited by: molecular-and-genomic-features.md
Momeni Boroujeni A, et al. Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors. Mod Pathol. 2022;35:1684-1694. PMID 36138078 — tags: [BAP1, ATRX, high-grade] — cited by: pathology-and-diagnosis.md, sarcomatous-overgrowth.md, molecular-and-genomic-features.md, recurrence-and-surveillance.md
de Kock L, et al. Significantly greater prevalence of DICER1 alterations in uterine embryonal rhabdomyosarcoma compared to adenosarcoma. Mod Pathol. 2020;33:1207-1219. PMID 31900434 — tags: [DICER1, ERMS-differential] — cited by: pathology-and-diagnosis.md, molecular-and-genomic-features.md
Apellaniz-Ruiz M, McCluggage WG, Foulkes WD. DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract. Genes Chromosomes Cancer. 2021;60:217-233. PMID 33135284 — tags: [DICER1, review] — cited by: pathology-and-diagnosis.md, molecular-and-genomic-features.md
Cousin S, et al. Targeting ERBB2 mutations in solid tumors: biological and clinical implications. J Hematol Oncol. 2018;11:86. PMID 29941010 — tags: [ERBB2, n-of-1] — cited by: adjuvant-and-systemic-therapy.md
Agaimy A, et al. ESR1::NCOA2/3 fusions in uterine neoplasms with adenosarcoma-like morphology: clinicopathologic and molecular features of 12 cases and review of the literature. Virchows Arch. 2026. PMID 41555057 — tags: [ESR1-fusion, adenosarcoma-like, UTROSCT-differential] — cited by: molecular-and-genomic-features.md

Epidemiology, registries, staging¶

Seagle BL, et al. Survival of women with Mullerian adenosarcoma: A National Cancer Data Base study. Gynecol Oncol. 2016;143:636-641. PMID 27771166 — tags: [landmark, NCDB, surgery, incidence-share] — cited by: overview.md, epidemiology-and-burden.md, staging-and-prognostic-factors.md, surgical-management.md, adjuvant-and-systemic-therapy.md
Arend R, et al. Long-term outcome and natural history of uterine adenosarcomas. Gynecol Oncol. 2010;119:305-8. PMID 20688363 — tags: [SEER, carcinosarcoma-comparison] — cited by: overview.md, epidemiology-and-burden.md, staging-and-prognostic-factors.md
Machida H, et al. Significance of lymph node metastasis on survival of women with uterine adenosarcoma. Gynecol Oncol. 2017;144:524-530. PMID 28109626 — tags: [SEER, lymphadenectomy] — cited by: overview.md, epidemiology-and-burden.md, staging-and-prognostic-factors.md, surgical-management.md, guidelines.md
Qu W, et al. Development and Validation of a Personalized Survival Prediction Model for Uterine Adenosarcoma: A Population-Based Deep Learning Study. Front Oncol. 2020;10:623818. PMID 33680946 — tags: [SEER, c-index, deep-learning] — cited by: overview.md, epidemiology-and-burden.md, staging-and-prognostic-factors.md
Tate K, et al. Uterine adenosarcoma in Japan: Clinicopathologic features, diagnosis and management. Asia Pac J Clin Oncol. 2018;14:318-325. PMID 29441675 — tags: [literature-assembled, lung-metastasis, misdiagnosis] — cited by: overview.md, pathology-and-diagnosis.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, recurrence-and-surveillance.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Brooks SE, et al. Surveillance, epidemiology, and end results analysis of 2677 cases of uterine sarcoma 1989-1999. Gynecol Oncol. 2004;93:204-8. PMID 15047237 — tags: [SEER, uterine-sarcoma-class, race] — cited by: epidemiology-and-burden.md, adjuvant-and-systemic-therapy.md
Nagase S, et al. Annual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology: Annual patient report for 2017. J Obstet Gynaecol Res. 2021;47:1631-1642. PMID 33631867 — tags: [JSOG-registry] — cited by: epidemiology-and-burden.md
Prat J. FIGO staging for uterine sarcomas. Int J Gynaecol Obstet. 2009;104:177-8. PMID 19135669 — tags: [FIGO-2009, staging] — cited by: staging-and-prognostic-factors.md, guidelines.md

Surgery, fertility, ovarian preservation¶

Nasioudis D, et al. Safety of ovarian preservation in premenopausal women with stage I uterine sarcoma. J Gynecol Oncol. 2017;28:e46. PMID 28541635 — tags: [SEER, ovarian-preservation] — cited by: overview.md, surgical-management.md, guidelines.md
L'Heveder A, et al. Conservative management of uterine adenosarcoma: lessons learned from 20 years of follow-up. Arch Gynecol Obstet. 2019;300:1383-1389. PMID 31584132 — tags: [fertility-sparing, case-report] — cited by: overview.md, epidemiology-and-burden.md, surgical-management.md, recurrence-and-surveillance.md, patient-experience-and-advocacy.md
Piątek S, et al. Fertility-Sparing Management May Be Considered in Young Women with Uterine Sarcoma. J Clin Med. 2022;11:4761. PMID 36012998 — tags: [fertility-sparing, mixed-histology] — cited by: surgical-management.md, patient-experience-and-advocacy.md

Systemic therapy, hormone therapy, recurrence¶

Nathenson MJ, et al. Treatment of Recurrent or Metastatic Uterine Adenosarcoma. Sarcoma. 2017;2017:4680273. PMID 29445312 — tags: [recurrent, doxorubicin, ifosfamide, salvage-surgery] — cited by: overview.md, surgical-management.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md, guidelines.md
Ioffe YJ, et al. Hormone receptor expression in uterine sarcomas: prognostic and therapeutic roles. Gynecol Oncol. 2009;115:466-71. PMID 19767065 — tags: [ER, mixed-sarcoma] — cited by: surgical-management.md, adjuvant-and-systemic-therapy.md
Benson C, Miah AB. Uterine sarcoma - current perspectives. Int J Womens Health. 2017;9:597-606. PMID 28919822 — tags: [uterine-sarcoma-class, systemic] — cited by: adjuvant-and-systemic-therapy.md
Ray-Coquard I, et al. A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in high-grade uterine sarcoma (EORTC62113). Int J Gynecol Cancer. 2020;30:1633-1637. PMID 32546554 — tags: [protocol, cabozantinib, high-grade] — cited by: clinical-trials-landscape.md

Imaging¶

Morikawa K, et al. Magnetic resonance imaging features of uterine adenosarcoma: case series and systematic review. Abdom Radiol (NY). 2025;50:3313-3326. PMID 39729099 — tags: [MRI, systematic-review] — cited by: overview.md, sarcomatous-overgrowth.md, clinical-presentation-and-imaging.md
Harada K, et al. Differentiating uterine adenosarcoma from endometrial polyps: MRI imaging features. Abdom Radiol (NY). 2025;50:5394-5404. PMID 40210681 — tags: [MRI, polyp-differential] — cited by: clinical-presentation-and-imaging.md
Toyoda S, et al. Unusual uterine cervical polypoid mass presenting during pregnancy. Cytopathology. 2022;33:409-411. PMID 34890128 — tags: [case-report, pregnancy, cervix] — cited by: clinical-presentation-and-imaging.md

Morcellation, occult sarcoma, tamoxifen¶

Raine-Bennett T, et al. Occult Uterine Sarcoma and Leiomyosarcoma: Incidence of and Survival Associated With Morcellation. Obstet Gynecol. 2016;127:29-39. PMID 26646120 — tags: [occult-sarcoma, morcellation, Kaiser] — cited by: overview.md, clinical-presentation-and-imaging.md, surgical-management.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Multinu F, et al. Incidence of sarcoma in patients undergoing hysterectomy for benign indications: a population-based study. Am J Obstet Gynecol. 2019;220:179.e1-179.e10. PMID 30447212 — tags: [occult-sarcoma, Olmsted] — cited by: clinical-presentation-and-imaging.md, surgical-management.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Krentel H, et al. Submucous uterine adenosarcoma-minimally invasive treatment. World J Surg Oncol. 2016;14:271. PMID 27769260 — tags: [case-report, morcellation] — cited by: red-flags-and-safety-concerns.md
Hur HC, et al. Fibroid morcellation: a shared clinical decision tool for mode of hysterectomy. Eur J Obstet Gynecol Reprod Biol. 2015;195:122-127. PMID 26520875 — tags: [decision-tool, morcellation] — cited by: red-flags-and-safety-concerns.md
Ceylan Y, et al. Mullerian adenosarcoma of the uterus associated with tamoxifen treatment for breast cancer. Turk J Obstet Gynecol. 2015. PMID 28913077 — tags: [case-report, tamoxifen] — cited by: clinical-presentation-and-imaging.md, red-flags-and-safety-concerns.md
Soh E, et al. Magnetic resonance imaging findings of tamoxifen-associated uterine Müllerian adenosarcoma: a case report. Acta Radiol. 2008. PMID 19143068 — tags: [case-report, tamoxifen, MRI] — cited by: clinical-presentation-and-imaging.md, red-flags-and-safety-concerns.md

Guidelines and consensus¶

Ray-Coquard I, et al. ESGO/EURACAN/GCIG guidelines for the management of patients with uterine sarcomas. Int J Gynecol Cancer. 2024;34:1499-1521. PMID 39322612 — tags: [guideline, ESGO, current] — cited by: overview.md, sarcomatous-overgrowth.md, surgical-management.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md, guidelines.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Karabajakian A, et al. Uterin adenosarcoma: French Guidelines of the French Sarcoma Group and the Rare Gynecologic Tumor Group. Bull Cancer. 2023;110:836-843. PMID 37202293 — tags: [guideline, French-GSF, adenosarcoma-specific] — cited by: overview.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, surgical-management.md, adjuvant-and-systemic-therapy.md, recurrence-and-surveillance.md, guidelines.md, red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Friedlander ML, et al. Gynecologic Cancer InterGroup (GCIG) consensus review for mullerian adenosarcoma of the female genital tract. Int J Gynecol Cancer. 2014;24:S78-82. PMID 25341585 — tags: [GCIG, consensus] — cited by: overview.md, epidemiology-and-burden.md, clinical-presentation-and-imaging.md, surgical-management.md, adjuvant-and-systemic-therapy.md, guidelines.md, clinical-trials-landscape.md
Abu-Rustum NR, et al. NCCN Guidelines Insights: Uterine Neoplasms, Version 3.2025. J Natl Compr Canc Netw. 2025;23:284-291. PMID 40763788 — tags: [NCCN, insights, endometrial-focused] — cited by: guidelines.md
Gronchi A, et al. Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2021;32:1348-1365. PMID 34303806 — tags: [ESMO, STS] — cited by: recurrence-and-surveillance.md, guidelines.md
ESMO / European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2012;23 Suppl 7:vii92-9. PMID 22997462 — tags: [ESMO, superseded] — cited by: guidelines.md
Casali PG, et al. Soft tissue sarcomas: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol. 2008;19 Suppl 2:ii89-93. PMID 18456783 — tags: [ESMO, superseded] — cited by: guidelines.md
Ferrandina G, et al. Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. Eur J Cancer. 2020;139:149-168. PMID 32992154 — tags: [SIGO, consensus] — cited by: guidelines.md
Ulrich UA, Denschlag D. Uterine Adenosarcoma. Oncol Res Treat. 2018;41:693-696. PMID 30326467 — tags: [practical-review] — cited by: overview.md, sarcomatous-overgrowth.md, epidemiology-and-burden.md, surgical-management.md, guidelines.md

Patient experience¶

den Hollander D, et al. 'I thought I had fibroids, and now I don't': a mixed method study on health-related quality of life in uterine sarcoma patients. Health Qual Life Outcomes. 2022;20:65. PMID 35443673 — tags: [HRQoL, qualitative, mixed-uterine-sarcoma] — cited by: red-flags-and-safety-concerns.md, patient-experience-and-advocacy.md
Ziegler E, et al. Fertility-sparing strategy in a rare case of uterine adenosarcoma and consecutive spontaneous pregnancy and livebirth. Arch Gynecol Obstet. 2026. PMID 42334466 — tags: [case-report, fertility-sparing, patient-perspective] — cited by: patient-experience-and-advocacy.md