What's new — Thoracic aortic aneurysm¶
Generated 2026-11-01 from the publication dates of every paper cited in this condition's pages.
This page answers a different question from the curation log. The log says when we last edited a page; this says how recent the evidence on those pages is — so you can tell settled ground from a field that is actively moving, and jump straight to what has emerged lately.
How much of this condition's evidence is recent¶
| Published within | Cited papers |
|---|---|
| last week | 0 |
| last month | 5 |
| last 2 months | 14 |
| last 3 months | 16 |
| last 6 months | 21 |
| last year | 34 |
| older than a year | 325 |
Counts are cumulative: a paper from last week also counts inside "last month". Dates are PubMed publication or e-publication dates, so a paper may have appeared online before its journal issue.
Newest evidence first¶
The most recent cited papers, with the pages that use them.
| Published | Paper | Cited on |
|---|---|---|
| 2026-10-02 | Circulating Lipids, Statins, and Metformin in Thoracic and Abdominal Aortic Aneurysm: A Systematic Review and Meta-Analysis — Life (Basel) ([PMID 42942351](https://pubmed.ncbi.nlm.nih.gov/42942351/){target="_blank" rel="noopener"}) | medical-therapy |
| 2026-10-02 | Early Outcomes of Thoracic Branch Endoprosthesis in Aortic Arch Pathologies: A Nordic Multicentre Study — Eur J Vasc Endovasc Surg ([PMID 42913781](https://pubmed.ncbi.nlm.nih.gov/42913781/){target="_blank" rel="noopener"}) | clinical-trials-landscape, surgical-and-endovascular-repair |
| 2026-10-02 | Multidisciplinary Collaboration in the Performance of Aortic Surgery: A Scientific Statement From the American Heart Association — Circulation ([PMID 42910416](https://pubmed.ncbi.nlm.nih.gov/42910416/){target="_blank" rel="noopener"}) | guidelines |
| 2026-10-02 | Adiposity and the risk of aortic dissection incidence and mortality: results from the UK Biobank, the J-SHC study and a meta-analysis of cohort studies — Eur J Epidemiol ([PMID 42902107](https://pubmed.ncbi.nlm.nih.gov/42902107/){target="_blank" rel="noopener"}) | epidemiology-and-natural-history |
| 2026-10-02 | Maternal and neonatal outcomes in Marfan syndrome: a nationwide registry — Heart ([PMID 41475970](https://pubmed.ncbi.nlm.nih.gov/41475970/){target="_blank" rel="noopener"}) | red-flags-and-safety-concerns |
| 2026-10-01 | Divergent aortic root cusp-to-cusp measurement techniques on CMR: geometric implications and threshold reclassification — Eur Heart J Imaging Methods Pract ([PMID 42890866](https://pubmed.ncbi.nlm.nih.gov/42890866/){target="_blank" rel="noopener"}) | imaging-and-surveillance |
| 2026-10-01 | Lived experiences of post-traumatic growth in patients with acute type A aortic dissection: A qualitative study — PLoS One ([PMID 42879453](https://pubmed.ncbi.nlm.nih.gov/42879453/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-10-01 | 1-Year Outcomes of Endovascular Repair of Zone 0/1 Aortic Arch Lesions with a Thoracic Branched Endoprosthesis — Ann Thorac Surg ([PMID 42863733](https://pubmed.ncbi.nlm.nih.gov/42863733/){target="_blank" rel="noopener"}) | clinical-trials-landscape, surgical-and-endovascular-repair |
| 2026-09-03 | Clinical Considerations for the Care of the Tactical Athlete With Cardiovascular Abnormalities: A Scientific Statement From the American College of Cardiology and the American Heart Association — Circulation ([PMID 42691142](https://pubmed.ncbi.nlm.nih.gov/42691142/){target="_blank" rel="noopener"}) | guidelines |
| 2026-09-02 | Genetic Patterns in Familial Thoracic Aortic Aneurysm Disease — Genes (Basel) ([PMID 42938321](https://pubmed.ncbi.nlm.nih.gov/42938321/){target="_blank" rel="noopener"}) | epidemiology-and-natural-history, genetics-of-taa |
| 2026-09-02 | Outcomes of thoracic endovascular aortic repair for uncomplicated subacute type B aortic dissection in the IRAD registry — J Vasc Surg ([PMID 42805273](https://pubmed.ncbi.nlm.nih.gov/42805273/){target="_blank" rel="noopener"}) | clinical-trials-landscape |
| 2026-09-02 | Co-creating a patient-driven digital monitoring agenda for thoracic aortic disease: a multiphase qualitative study — BMJ Open ([PMID 42790905](https://pubmed.ncbi.nlm.nih.gov/42790905/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-09-02 | Health-related quality of life, psychological well-being and physical activity in patients with mild-to-moderate ascending aortic dilation - a cross-sectional case-control study — BMC Cardiovasc Disord ([PMID 42768306](https://pubmed.ncbi.nlm.nih.gov/42768306/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-09-01 | Thoracic aortic disease: prognostic role of gene variants and polygenic risk scores — Eur Heart J ([PMID 42678067](https://pubmed.ncbi.nlm.nih.gov/42678067/){target="_blank" rel="noopener"}) | omics-and-emerging-science |
| 2026-08-14 | The aorta in Marfan syndrome: from molecular mechanisms to mechanobiological dysfunction — Cardiovasc Res ([PMID 42140666](https://pubmed.ncbi.nlm.nih.gov/42140666/){target="_blank" rel="noopener"}) | animal-models, hemodynamics-and-biomechanics, pathophysiology |
| 2026-08-03 | CIRSE Standards of Practice on the Endovascular Management of Descending Thoracic Aortic Disease — Cardiovasc Intervent Radiol ([PMID 42545482](https://pubmed.ncbi.nlm.nih.gov/42545482/){target="_blank" rel="noopener"}) | guidelines |
| 2026-07-08 | From survival to lifelong care: The role of patient organisations in aortic dissection — Am Heart J Plus ([PMID 42491301](https://pubmed.ncbi.nlm.nih.gov/42491301/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-06-03 | Preclinical modeling of Loeys-Dietz syndrome: insights into mechanisms and therapy — Orphanet J Rare Dis ([PMID 42380922](https://pubmed.ncbi.nlm.nih.gov/42380922/){target="_blank" rel="noopener"}) | animal-models |
| 2026-06-02 | Management of pregnancy in women with rare multisystemic vascular diseases: a qualitative survey analysis — Orphanet J Rare Dis ([PMID 42365315](https://pubmed.ncbi.nlm.nih.gov/42365315/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-06-01 | Cardiac Rehabilitation Improves Outcomes After Thoracic Aortic Aneurysm Repair — JACC Asia ([PMID 42283670](https://pubmed.ncbi.nlm.nih.gov/42283670/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-06-01 | Psychological experiences of patients with Stanford type B aortic dissection during the preoperative waiting period: a qualitative study — BMC Cardiovasc Disord ([PMID 42277648](https://pubmed.ncbi.nlm.nih.gov/42277648/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-05-01 | Ten-year outcomes of valve-replacing versus valve-sparing aortic root replacement in patients with Marfan syndrome: An observational multicenter study — J Thorac Cardiovasc Surg ([PMID 42128131](https://pubmed.ncbi.nlm.nih.gov/42128131/){target="_blank" rel="noopener"}) | surgical-and-endovascular-repair |
| 2026-05-01 | Fatal Aortic Rupture at Term Pregnancy Caused by Vascular Ehlers-Danlos Syndrome Diagnosed by Postmortem Genetic Testing Using Formalin-Fixed, Paraffin-Embedded Tissue — J Obstet Gynaecol Res ([PMID 42092737](https://pubmed.ncbi.nlm.nih.gov/42092737/){target="_blank" rel="noopener"}) | red-flags-and-safety-concerns |
| 2026-04-02 | Nonlinear and Episodic Growth in the Natural History of Ascending Aortic Dilation — Can J Cardiol ([PMID 41935738](https://pubmed.ncbi.nlm.nih.gov/41935738/){target="_blank" rel="noopener"}) | epidemiology-and-natural-history |
| 2026-04-01 | Spatial and single-cell RNA sequencing reveals the immune microenvironment of human ascending thoracic aortic aneurysms — Clin Transl Med ([PMID 42007493](https://pubmed.ncbi.nlm.nih.gov/42007493/){target="_blank" rel="noopener"}) | omics-and-emerging-science |
| 2026-04-01 | MYH11 variants in thoracic aortic aneurysm pathophysiology: From bench to bedside — Eur J Clin Invest ([PMID 41891259](https://pubmed.ncbi.nlm.nih.gov/41891259/){target="_blank" rel="noopener"}) | animal-models |
| 2026-03-02 | Desmosine in Aortic Disease: Biology, Measurement, and Clinical Applications in Aortic Pathologies — J Clin Med ([PMID 41976840](https://pubmed.ncbi.nlm.nih.gov/41976840/){target="_blank" rel="noopener"}) | biomarkers |
| 2026-03-02 | Patient and family perspectives on cascade screening for thoracic aortic disease: a mixed-methods evaluation — Eur J Hum Genet ([PMID 41772284](https://pubmed.ncbi.nlm.nih.gov/41772284/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-03-01 | Lost to follow-up: A narrative review of socioeconomic, psychosocial, and systemic barriers to aortic dissection surveillance — Semin Vasc Surg ([PMID 42285644](https://pubmed.ncbi.nlm.nih.gov/42285644/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-03-01 | Evolving dynamic needs for patient-reported outcomes assessment in individuals with an abdominal aortic aneurysm (AAA): A systematic review — Vasc Med ([PMID 41854119](https://pubmed.ncbi.nlm.nih.gov/41854119/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-02-01 | Role of illicit drug use in Type B aortic dissection and trial participation — Semin Vasc Surg ([PMID 42285641](https://pubmed.ncbi.nlm.nih.gov/42285641/){target="_blank" rel="noopener"}) | red-flags-and-safety-concerns |
| 2026-01-02 | Plasma Desmosine Is Elevated in Thoracoabdominal Aortic Aneurysms and Is Associated with Intramural Proteolytic Activity — Int J Mol Sci ([PMID 41683665](https://pubmed.ncbi.nlm.nih.gov/41683665/){target="_blank" rel="noopener"}) | biomarkers |
| 2025-11-02 | Applications of Artificial Intelligence as a Prognostic Tool in the Management of Acute Aortic Syndrome and Aneurysm: A Comprehensive Review — J Clin Med ([PMID 41375721](https://pubmed.ncbi.nlm.nih.gov/41375721/){target="_blank" rel="noopener"}) | omics-and-emerging-science |
| 2025-11-01 | One-Year Results of Novel Aortic Arch Hybrid Prosthesis for Repair of Acute DeBakey Type I Dissection With Malperfusion: PERSEVERE Study — Ann Thorac Surg ([PMID 41238072](https://pubmed.ncbi.nlm.nih.gov/41238072/){target="_blank" rel="noopener"}) | clinical-trials-landscape |
Trials — what has moved¶
53 registered trials are cited by this condition's pages. Registry records were re-checked live when this page was generated, so status, enrolment and results-posting below reflect ClinicalTrials.gov as of that date.
| Registry activity | Trials |
|---|---|
| trial records updated in the last week | 1 |
| trial records updated in the last month | 2 |
| trial records updated in the last 2 months | 5 |
| trial records updated in the last 3 months | 7 |
| trial records updated in the last 6 months | 9 |
| trial records updated in the last year | 16 |
Recently updated registrations¶
| Updated | Trial | Phase | Status | N | Cited on |
|---|---|---|---|---|---|
| 2026-10-30 | GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study | NA | RECRUITING | 125 | clinical-trials-landscape |
| 2026-10-23 | GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections | NA | ACTIVE_NOT_RECRUITING | 112 | clinical-trials-landscape |
| 2026-09-30 | Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic | NA | RECRUITING | 72 | clinical-trials-landscape |
| 2026-09-28 | Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance | NA | RECRUITING | 610 | biomarkers, clinical-trials-landscape, guidelines, omics-and-emerging-science, risk-stratification-and-size-thresholds |
| 2026-09-10 | Evaluation of the GORE® TBE Device in the Treatment of Lesions of the Aortic Arch and Desc | NA | ACTIVE_NOT_RECRUITING | 79 | clinical-trials-landscape, surgical-and-endovascular-repair |
| 2026-08-20 | PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches | NA | RECRUITING | 2000 | clinical-trials-landscape |
| 2026-08-14 | Using the EHR to Advance Genomic Medicine Across a Diverse Health System | NA | RECRUITING | 1000 | clinical-trials-landscape |
| 2026-06-08 | HEART: Pilot Randomized Controlled Trial | PHASE1, PHASE2 | RECRUITING | 50 | clinical-trials-landscape |
| 2026-05-29 | Evaluation of the GORE® Ascending Stent Graft | NA | ENROLLING_BY_INVITATION | 370 | clinical-trials-landscape |
| 2026-03-27 | Nutritional Ketosis Marfan | NA | NOT_YET_RECRUITING | 15 | clinical-trials-landscape |
| 2026-03-23 | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-i | NA | RECRUITING | 30 | clinical-trials-landscape |
| 2026-03-02 | Feasibility of Endovascular Repair of Ascending Aortic Pathologies | NA | TERMINATED | 1 | clinical-trials-landscape |
| 2026-02-13 | Pathogenetic Basis of Aortopathy and Aortic Valve Disease | NA | ACTIVE_NOT_RECRUITING | 3000 | clinical-trials-landscape |
| 2026-02-12 | Aspirin for Prevention of Stroke After Endovascular Aortic Arch Repair: a Multicenter, Dou | EARLY_PHASE1 | NOT_YET_RECRUITING | 224 | clinical-trials-landscape |
| 2026-01-29 | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-i | NA | NOT_YET_RECRUITING | 15 | clinical-trials-landscape |
Posted efficacy and safety results¶
Trials whose sponsors have posted results to the registry. Adverse-event figures are participant counts summed across all arms as reported — read them against enrolment, and follow the registry link for the arm-by-arm breakdown that determines whether a signal is real.
| Results posted | Trial | Phase | N | Primary outcome | Serious AE | Other AE | Deaths |
|---|---|---|---|---|---|---|---|
| 2026-03-02 | Feasibility of Endovascular Repair of Ascending Aortic Pathologies | NA | 1 | Number of Participants With Freedom From Early Death | 1 | 0 | 0 |
| 2025-06-25 | Evaluation of the GORE® TBE Device in the Treatment of Lesions of the | NA | 79 | Proportion of Participants With Primary Endpoint Success Through 1 Mon | 63 | 63 | 22 |
| 2021-11-26 | Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial | PHASE2 | 261 | Difference in Z-score for Rank of Maximum Transverse Diameter (MTD) Re | 141 | 232 | 7 |
| 2017-05-04 | Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Pa | PHASE3 | 30 | Central Aortic Distensibility by MRI | 2 | 12 | 0 |
| 2015-04-01 | Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement | PHASE3 | 608 | Annual Rate of Change in Aortic Root (Sinuses of Valsalva) Body-surfac | 60 | 256 | 0 |
| 2014-09-01 | Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiff | PHASE3 | 40 | Aortic Biophysical Properties - Pulse Wave Velocity | 0 | 0 | 0 |
24 of these trials are still recruiting or active — see the condition's clinical trials page for the full landscape.
Which pages rest on the newest evidence¶
🔥 marks a page citing three or more papers from the last year — the pages worth re-reading if you have been away.
| Page | Newest citation | In last year | Total citations |
|---|---|---|---|
| clinical-trials-landscape | 2026-10-02 | 4 | 20 |
| epidemiology-and-natural-history | 2026-10-02 | 3 | 28 |
| guidelines | 2026-10-02 | 3 | 26 |
| medical-therapy | 2026-10-02 | 1 | 22 |
| red-flags-and-safety-concerns | 2026-10-02 | 3 | 44 |
| surgical-and-endovascular-repair | 2026-10-02 | 3 | 20 |
| imaging-and-surveillance | 2026-10-01 | 1 | 11 |
| patient-experience-and-advocacy | 2026-10-01 | 10 | 46 |
| genetics-of-taa | 2026-09-02 | 1 | 28 |
| omics-and-emerging-science | 2026-09-01 | 3 | 32 |
| animal-models | 2026-08-14 | 3 | 39 |
| hemodynamics-and-biomechanics | 2026-08-14 | 1 | 22 |
| pathophysiology | 2026-08-14 | 1 | 43 |
| biomarkers | 2026-03-02 | 2 | 38 |
| anatomy-and-classification | 2022-11-02 | 0 | 15 |
| aortic-dissection | 2022-11-02 | 0 | 27 |
| overview | 2022-11-02 | 0 | 22 |
| risk-stratification-and-size-thresholds | 2022-11-02 | 0 | 16 |
| syndromic-aortopathies | 2021-09-02 | 0 | 18 |
| bicuspid-aortopathy | 2021-07-02 | 0 | 14 |
Recency is not quality: an old paper may be the definitive one, and a new paper may not replicate. Use this to find movement, not to rank evidence. See open questions for what remains unresolved, and the curation log for when these pages were last revised.