What's new — Thoracic aortic aneurysm¶
Generated 2026-09-03 from the publication dates of every paper cited in this condition's pages.
This page answers a different question from the curation log. The log says when we last edited a page; this says how recent the evidence on those pages is — so you can tell settled ground from a field that is actively moving, and jump straight to what has emerged lately.
How much of this condition's evidence is recent¶
| Published within | Cited papers |
|---|---|
| last week | 0 |
| last month | 1 |
| last 2 months | 2 |
| last 3 months | 2 |
| last 6 months | 8 |
| last year | 18 |
| older than a year | 323 |
Counts are cumulative: a paper from last week also counts inside "last month". Dates are PubMed publication or e-publication dates, so a paper may have appeared online before its journal issue.
Newest evidence first¶
The most recent cited papers, with the pages that use them.
| Published | Paper | Cited on |
|---|---|---|
| 2026-08-14 | The aorta in Marfan syndrome: from molecular mechanisms to mechanobiological dysfunction — Cardiovasc Res ([PMID 42140666](https://pubmed.ncbi.nlm.nih.gov/42140666/){target="_blank" rel="noopener"}) | animal-models, hemodynamics-and-biomechanics, pathophysiology |
| 2026-07-08 | From survival to lifelong care: The role of patient organisations in aortic dissection — Am Heart J Plus ([PMID 42491301](https://pubmed.ncbi.nlm.nih.gov/42491301/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-06-03 | Preclinical modeling of Loeys-Dietz syndrome: insights into mechanisms and therapy — Orphanet J Rare Dis ([PMID 42380922](https://pubmed.ncbi.nlm.nih.gov/42380922/){target="_blank" rel="noopener"}) | animal-models |
| 2026-06-02 | Management of pregnancy in women with rare multisystemic vascular diseases: a qualitative survey analysis — Orphanet J Rare Dis ([PMID 42365315](https://pubmed.ncbi.nlm.nih.gov/42365315/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-06-01 | Psychological experiences of patients with Stanford type B aortic dissection during the preoperative waiting period: a qualitative study — BMC Cardiovasc Disord ([PMID 42277648](https://pubmed.ncbi.nlm.nih.gov/42277648/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-05-01 | Fatal Aortic Rupture at Term Pregnancy Caused by Vascular Ehlers-Danlos Syndrome Diagnosed by Postmortem Genetic Testing Using Formalin-Fixed, Paraffin-Embedded Tissue — J Obstet Gynaecol Res ([PMID 42092737](https://pubmed.ncbi.nlm.nih.gov/42092737/){target="_blank" rel="noopener"}) | red-flags-and-safety-concerns |
| 2026-04-01 | Spatial and single-cell RNA sequencing reveals the immune microenvironment of human ascending thoracic aortic aneurysms — Clin Transl Med ([PMID 42007493](https://pubmed.ncbi.nlm.nih.gov/42007493/){target="_blank" rel="noopener"}) | omics-and-emerging-science |
| 2026-04-01 | MYH11 variants in thoracic aortic aneurysm pathophysiology: From bench to bedside — Eur J Clin Invest ([PMID 41891259](https://pubmed.ncbi.nlm.nih.gov/41891259/){target="_blank" rel="noopener"}) | animal-models |
| 2026-03-02 | Desmosine in Aortic Disease: Biology, Measurement, and Clinical Applications in Aortic Pathologies — J Clin Med ([PMID 41976840](https://pubmed.ncbi.nlm.nih.gov/41976840/){target="_blank" rel="noopener"}) | biomarkers |
| 2026-03-02 | Patient and family perspectives on cascade screening for thoracic aortic disease: a mixed-methods evaluation — Eur J Hum Genet ([PMID 41772284](https://pubmed.ncbi.nlm.nih.gov/41772284/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-03-01 | Lost to follow-up: A narrative review of socioeconomic, psychosocial, and systemic barriers to aortic dissection surveillance — Semin Vasc Surg ([PMID 42285644](https://pubmed.ncbi.nlm.nih.gov/42285644/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-03-01 | Evolving dynamic needs for patient-reported outcomes assessment in individuals with an abdominal aortic aneurysm (AAA): A systematic review — Vasc Med ([PMID 41854119](https://pubmed.ncbi.nlm.nih.gov/41854119/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
| 2026-02-01 | Role of illicit drug use in Type B aortic dissection and trial participation — Semin Vasc Surg ([PMID 42285641](https://pubmed.ncbi.nlm.nih.gov/42285641/){target="_blank" rel="noopener"}) | red-flags-and-safety-concerns |
| 2026-01-02 | Plasma Desmosine Is Elevated in Thoracoabdominal Aortic Aneurysms and Is Associated with Intramural Proteolytic Activity — Int J Mol Sci ([PMID 41683665](https://pubmed.ncbi.nlm.nih.gov/41683665/){target="_blank" rel="noopener"}) | biomarkers |
| 2025-12-03 | Maternal and neonatal outcomes in Marfan syndrome: a nationwide registry — Heart ([PMID 41475970](https://pubmed.ncbi.nlm.nih.gov/41475970/){target="_blank" rel="noopener"}) | red-flags-and-safety-concerns |
| 2025-11-02 | Applications of Artificial Intelligence as a Prognostic Tool in the Management of Acute Aortic Syndrome and Aneurysm: A Comprehensive Review — J Clin Med ([PMID 41375721](https://pubmed.ncbi.nlm.nih.gov/41375721/){target="_blank" rel="noopener"}) | omics-and-emerging-science |
| 2025-11-01 | One-Year Results of Novel Aortic Arch Hybrid Prosthesis for Repair of Acute DeBakey Type I Dissection With Malperfusion: PERSEVERE Study — Ann Thorac Surg ([PMID 41238072](https://pubmed.ncbi.nlm.nih.gov/41238072/){target="_blank" rel="noopener"}) | clinical-trials-landscape |
| 2025-10-07 | Thoracic aortic diseases: Identification of diagnostic biomarkers using proteomic analysis — Cardiovasc Pathol ([PMID 41061941](https://pubmed.ncbi.nlm.nih.gov/41061941/){target="_blank" rel="noopener"}) | omics-and-emerging-science |
Trials — what has moved¶
51 registered trials are cited by this condition's pages. Registry records were re-checked live when this page was generated, so status, enrolment and results-posting below reflect ClinicalTrials.gov as of that date.
| Registry activity | Trials |
|---|---|
| trial records updated in the last week | 0 |
| trial records updated in the last month | 3 |
| trial records updated in the last 2 months | 3 |
| trial records updated in the last 3 months | 4 |
| trial records updated in the last 6 months | 7 |
| trial records updated in the last year | 16 |
Recently updated registrations¶
| Updated | Trial | Phase | Status | N | Cited on |
|---|---|---|---|---|---|
| 2026-08-20 | PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches | NA | RECRUITING | 2000 | clinical-trials-landscape |
| 2026-08-14 | Using the EHR to Advance Genomic Medicine Across a Diverse Health System | NA | RECRUITING | 1000 | clinical-trials-landscape |
| 2026-08-11 | GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections | NA | RECRUITING | 112 | clinical-trials-landscape |
| 2026-06-08 | HEART: Pilot Randomized Controlled Trial | PHASE1, PHASE2 | RECRUITING | 50 | clinical-trials-landscape |
| 2026-05-29 | Evaluation of the GORE® Ascending Stent Graft | NA | ENROLLING_BY_INVITATION | 370 | clinical-trials-landscape |
| 2026-03-27 | Nutritional Ketosis Marfan | NA | NOT_YET_RECRUITING | 15 | clinical-trials-landscape |
| 2026-03-23 | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-i | NA | RECRUITING | 30 | clinical-trials-landscape |
| 2026-03-02 | Feasibility of Endovascular Repair of Ascending Aortic Pathologies | NA | TERMINATED | 1 | clinical-trials-landscape |
| 2026-02-13 | Pathogenetic Basis of Aortopathy and Aortic Valve Disease | NA | ACTIVE_NOT_RECRUITING | 3000 | clinical-trials-landscape |
| 2026-02-12 | Aspirin for Prevention of Stroke After Endovascular Aortic Arch Repair: a Multicenter, Dou | EARLY_PHASE1 | NOT_YET_RECRUITING | 224 | clinical-trials-landscape |
| 2026-01-29 | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-i | NA | NOT_YET_RECRUITING | 15 | clinical-trials-landscape |
| 2026-01-23 | Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride | PHASE1 | COMPLETED | 9 | clinical-trials-landscape |
| 2025-09-29 | Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic | NA | RECRUITING | 72 | clinical-trials-landscape |
| 2025-09-22 | Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance | NA | RECRUITING | 610 | biomarkers, clinical-trials-landscape, guidelines, omics-and-emerging-science, risk-stratification-and-size-thresholds |
| 2025-09-12 | Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle | PHASE1 | RECRUITING | 15 | clinical-trials-landscape, omics-and-emerging-science |
Posted efficacy and safety results¶
Trials whose sponsors have posted results to the registry. Adverse-event figures are participant counts summed across all arms as reported — read them against enrolment, and follow the registry link for the arm-by-arm breakdown that determines whether a signal is real.
| Results posted | Trial | Phase | N | Primary outcome | Serious AE | Other AE | Deaths |
|---|---|---|---|---|---|---|---|
| 2026-03-02 | Feasibility of Endovascular Repair of Ascending Aortic Pathologies | NA | 1 | Number of Participants With Freedom From Early Death | 1 | 0 | 0 |
| 2021-11-26 | Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial | PHASE2 | 261 | Difference in Z-score for Rank of Maximum Transverse Diameter (MTD) Re | 141 | 232 | 7 |
| 2017-05-04 | Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Pa | PHASE3 | 30 | Central Aortic Distensibility by MRI | 2 | 12 | 0 |
| 2015-04-01 | Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement | PHASE3 | 608 | Annual Rate of Change in Aortic Root (Sinuses of Valsalva) Body-surfac | 60 | 256 | 0 |
| 2014-09-01 | Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiff | PHASE3 | 40 | Aortic Biophysical Properties - Pulse Wave Velocity | 0 | 0 | 0 |
22 of these trials are still recruiting or active — see the condition's clinical trials page for the full landscape.
Which pages rest on the newest evidence¶
🔥 marks a page citing three or more papers from the last year — the pages worth re-reading if you have been away.
| Page | Newest citation | In last year | Total citations |
|---|---|---|---|
| animal-models | 2026-08-14 | 3 | 39 |
| hemodynamics-and-biomechanics | 2026-08-14 | 1 | 22 |
| pathophysiology | 2026-08-14 | 1 | 43 |
| patient-experience-and-advocacy | 2026-07-08 | 6 | 41 |
| red-flags-and-safety-concerns | 2026-05-01 | 3 | 44 |
| omics-and-emerging-science | 2026-04-01 | 3 | 31 |
| biomarkers | 2026-03-02 | 2 | 38 |
| clinical-trials-landscape | 2025-11-01 | 1 | 17 |
| guidelines | 2024-09-02 | 0 | 22 |
| genetics-of-taa | 2023-02-01 | 0 | 27 |
| anatomy-and-classification | 2022-11-02 | 0 | 15 |
| aortic-dissection | 2022-11-02 | 0 | 27 |
| imaging-and-surveillance | 2022-11-02 | 0 | 10 |
| medical-therapy | 2022-11-02 | 0 | 21 |
| overview | 2022-11-02 | 0 | 22 |
| risk-stratification-and-size-thresholds | 2022-11-02 | 0 | 16 |
| surgical-and-endovascular-repair | 2022-11-02 | 0 | 17 |
| epidemiology-and-natural-history | 2021-09-02 | 0 | 25 |
| syndromic-aortopathies | 2021-09-02 | 0 | 18 |
| bicuspid-aortopathy | 2021-07-02 | 0 | 14 |
Recency is not quality: an old paper may be the definitive one, and a new paper may not replicate. Use this to find movement, not to rank evidence. See open questions for what remains unresolved, and the curation log for when these pages were last revised.