What's new — Neuropathic pain¶
Generated 2026-11-01 from the publication dates of every paper cited in this condition's pages.
This page answers a different question from the curation log. The log says when we last edited a page; this says how recent the evidence on those pages is — so you can tell settled ground from a field that is actively moving, and jump straight to what has emerged lately.
How much of this condition's evidence is recent¶
| Published within | Cited papers |
|---|---|
| last week | 2 |
| last month | 4 |
| last 2 months | 17 |
| last 3 months | 19 |
| last 6 months | 22 |
| last year | 24 |
| older than a year | 286 |
Counts are cumulative: a paper from last week also counts inside "last month". Dates are PubMed publication or e-publication dates, so a paper may have appeared online before its journal issue.
Newest evidence first¶
The most recent cited papers, with the pages that use them.
| Published | Paper | Cited on |
|---|---|---|
| 2026-11-01 | Evidence on Glutathione and Boosters for Prevention of Chemotherapy-Induced Neuropathy: A Systematic Review and Network Meta-Analysis — Basic Clin Pharmacol Toxicol ([PMID 42876024](https://pubmed.ncbi.nlm.nih.gov/42876024/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-11-01 | Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory) — Diabetes Care ([PMID 42713876](https://pubmed.ncbi.nlm.nih.gov/42713876/){target="_blank" rel="noopener"}) | clinical-trials-landscape, diabetic-neuropathic-pain, neuromodulation |
| 2026-10-06 | Efficacy of Cryotherapy in Preventing Taxane-Induced Neuropathy: The CryoPac Randomised Controlled Trial — Ann Oncol ([PMID 42838271](https://pubmed.ncbi.nlm.nih.gov/42838271/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy, clinical-trials-landscape |
| 2026-10-02 | Efficacy and Safety of Crisugabalin for Inadequately Controlled Diabetic Peripheral Neuropathic Pain: A Randomized, Active-Controlled, Phase 2 Trial — Diabetes Obes Metab ([PMID 42823911](https://pubmed.ncbi.nlm.nih.gov/42823911/){target="_blank" rel="noopener"}) | diabetic-neuropathic-pain |
| 2026-10-01 | Herpes Zoster Vaccination in Patients with Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis of Vaccine Efficacy, Effectiveness, and Safety — Int J Infect Dis ([PMID 42896729](https://pubmed.ncbi.nlm.nih.gov/42896729/){target="_blank" rel="noopener"}) | postherpetic-and-postsurgical-pain |
| 2026-10-01 | Longitudinal plasma phosphorylated neurofilament-heavy chain levels in oxaliplatin-induced peripheral neuropathy: a prospective multi-institutional exploratory study — Cancer Chemother Pharmacol ([PMID 42873277](https://pubmed.ncbi.nlm.nih.gov/42873277/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-09-09 | Preventive effect of goshajinkigan on paclitaxel-induced peripheral neuropathy: an open-label, randomized phase II study (OLCSG2101) — Oncologist ([PMID 42750137](https://pubmed.ncbi.nlm.nih.gov/42750137/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-09-04 | Prevalence and Study-Level Predictors of Chronic Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis — J Pain Res ([PMID 42713463](https://pubmed.ncbi.nlm.nih.gov/42713463/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy, epidemiology-and-burden |
| 2026-09-03 | Evaluation of the efficacy of duloxetine and venlafaxine in chemotherapy-induced neuropathy in cancer patients: a double-blind multicenter randomized clinical trial — Ann Med Surg (Lond) ([PMID 42866777](https://pubmed.ncbi.nlm.nih.gov/42866777/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-09-03 | Multifactorial Contributors to Dose Limiting and Post-Treatment Neurologic Toxicity During Chemotherapy Treatment — Neurology ([PMID 42814908](https://pubmed.ncbi.nlm.nih.gov/42814908/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-09-02 | Perioperative intravenous lidocaine for the prevention of chronic postsurgical pain: a systematic review and meta-analysis of randomized controlled trials — Front Med (Lausanne) ([PMID 42865434](https://pubmed.ncbi.nlm.nih.gov/42865434/){target="_blank" rel="noopener"}) | postherpetic-and-postsurgical-pain |
| 2026-09-02 | Reduced oxaliplatin exposure in gastrointestinal cancers: A systematic review and meta-analysis — Cancer Treat Rev ([PMID 42801795](https://pubmed.ncbi.nlm.nih.gov/42801795/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-09-01 | Reply to the Comment by Finnerup and Gylfadottir Regarding 'Lesion Without Pain, Pain Without Certainty: A Critical Reappraisal of the NeuPSIG Diagnostic Algorithm for Neuropathic Pain' — Eur J Pain ([PMID 42765589](https://pubmed.ncbi.nlm.nih.gov/42765589/){target="_blank" rel="noopener"}) | definition-grading-and-diagnosis |
| 2026-09-01 | Assessment of blinding in pharmacotherapy and noninvasive neuromodulation randomized controlled trials for neuropathic pain in adults — Pain ([PMID 42751722](https://pubmed.ncbi.nlm.nih.gov/42751722/){target="_blank" rel="noopener"}) | clinical-trials-landscape |
| 2026-09-01 | Efficacy and Effectiveness of the Recombinant Zoster Vaccine Against Herpes Zoster, Herpes Zoster Ophthalmicus, Postherpetic Neuralgia and Dementia: A Systematic Review and Meta-Analysis — Rev Med Virol ([PMID 42748460](https://pubmed.ncbi.nlm.nih.gov/42748460/){target="_blank" rel="noopener"}) | postherpetic-and-postsurgical-pain |
| 2026-09-01 | Comment on "Lesion Without Pain, Pain Without Certainty: A Critical Reappraisal of the NeuPSIG Diagnostic Algorithm for Neuropathic Pain" — Eur J Pain ([PMID 42708623](https://pubmed.ncbi.nlm.nih.gov/42708623/){target="_blank" rel="noopener"}) | definition-grading-and-diagnosis |
| 2026-09-01 | The Prevalence of Neuropathic Pain in Multiple Sclerosis-A Systematic Review and Meta-Analysis Using the NeuPSIG Algorithm — Eur J Pain ([PMID 42678174](https://pubmed.ncbi.nlm.nih.gov/42678174/){target="_blank" rel="noopener"}) | definition-grading-and-diagnosis |
| 2026-08-07 | The efficacy, immunogenicity and safety of the LZ901 vaccine for herpes zoster virus in adults 40 years of age or older: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial — Nat Commun ([PMID 42733065](https://pubmed.ncbi.nlm.nih.gov/42733065/){target="_blank" rel="noopener"}) | postherpetic-and-postsurgical-pain |
| 2026-08-02 | Glucagon-like peptide-1 receptor agonist treatment is associated with lower frequency of diabetic peripheral neuropathy and neuropathic pain in type 2 diabetes — Pain ([PMID 42663556](https://pubmed.ncbi.nlm.nih.gov/42663556/){target="_blank" rel="noopener"}) | diabetic-neuropathic-pain |
| 2026-08-01 | Lesion Without Pain, Pain Without Certainty: A Critical Reappraisal of the NeuPSIG Diagnostic Algorithm for Neuropathic Pain — Eur J Pain ([PMID 42550034](https://pubmed.ncbi.nlm.nih.gov/42550034/){target="_blank" rel="noopener"}) | definition-grading-and-diagnosis |
| 2026-07-09 | PROSPER: a phase III trial of lecithinized superoxide dismutase to prevent oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer — ESMO Gastrointest Oncol ([PMID 42583153](https://pubmed.ncbi.nlm.nih.gov/42583153/){target="_blank" rel="noopener"}) | chemotherapy-and-toxic-neuropathy |
| 2026-07-01 | New insight into RNA biomarkers in neuropathic pain: a clinician-neuroscientist roadmap to translational testing and treatment monitoring a clinical review — Front Pain Res (Lausanne) ([PMID 42534835](https://pubmed.ncbi.nlm.nih.gov/42534835/){target="_blank" rel="noopener"}) | biomarkers |
| 2025-12-01 | Suzetrigine, a selective NaV1.8 inhibitor in acute and chronic pain: mechanistic insights, clinical outcomes, and future perspectives — Curr Opin Anaesthesiol ([PMID 41481839](https://pubmed.ncbi.nlm.nih.gov/41481839/){target="_blank" rel="noopener"}) | clinical-trials-landscape |
| 2025-11-02 | Evaluating pain and neurological function with high frequency 10 kHz spinal cord stimulation in the treatment of painful diabetic neuropathy: design of a multicentre, randomised controlled trial (PDN-Sensory) — BMJ Open ([PMID 41309477](https://pubmed.ncbi.nlm.nih.gov/41309477/){target="_blank" rel="noopener"}) | clinical-trials-landscape |
Trials — what has moved¶
23 registered trials are cited by this condition's pages. Registry records were re-checked live when this page was generated, so status, enrolment and results-posting below reflect ClinicalTrials.gov as of that date.
| Registry activity | Trials |
|---|---|
| trial records updated in the last week | 1 |
| trial records updated in the last month | 3 |
| trial records updated in the last 2 months | 5 |
| trial records updated in the last 3 months | 6 |
| trial records updated in the last 6 months | 12 |
| trial records updated in the last year | 13 |
Recently updated registrations¶
Posted efficacy and safety results¶
Trials whose sponsors have posted results to the registry. Adverse-event figures are participant counts summed across all arms as reported — read them against enrolment, and follow the registry link for the arm-by-arm breakdown that determines whether a signal is real.
| Results posted | Trial | Phase | N | Primary outcome | Serious AE | Other AE | Deaths |
|---|---|---|---|---|---|---|---|
| 2026-09-21 | Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Tre | PHASE3 | 412 | Change From Baseline in the 24-Hour Average Pain Intensity (API) Betwe | 22 | 152 | 0 |
| 2026-07-30 | A Study of LY3556050 in Adult Participants With Diabetic Peripheral Ne | PHASE2 | 404 | Mean Change From Baseline in Average Pain Intensity (API) as Measured | 11 | 71 | 1 |
| 2025-07-01 | Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Perip | PHASE2 | 194 | Change From Baseline in the Weekly Average of Daily Pain Intensity on | 4 | 28 | 1 |
| 2023-11-22 | Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pai | NA | 4 | Visual Analog Score | 2 | 10 | 0 |
| 2023-09-21 | Ricolinostat in Patients With Painful Diabetic Peripheral Neuropathy | PHASE2 | 282 | Change in Mean Average Pain Intensity (NRS) | 12 | 58 | 0 |
| 2011-12-08 | A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain D | PHASE3 | 220 | Duration Adjusted Average Change (DAAC) of Mean Pain Score | 19 | 134 | 0 |
15 of these trials are still recruiting or active — see the condition's clinical trials page for the full landscape.
Which pages rest on the newest evidence¶
🔥 marks a page citing three or more papers from the last year — the pages worth re-reading if you have been away.
| Page | Newest citation | In last year | Total citations |
|---|---|---|---|
| chemotherapy-and-toxic-neuropathy | 2026-11-01 | 9 | 40 |
| clinical-trials-landscape | 2026-11-01 | 5 | 33 |
| diabetic-neuropathic-pain | 2026-11-01 | 3 | 33 |
| neuromodulation | 2026-11-01 | 1 | 31 |
| postherpetic-and-postsurgical-pain | 2026-10-01 | 4 | 35 |
| epidemiology-and-burden | 2026-09-04 | 1 | 30 |
| definition-grading-and-diagnosis | 2026-09-01 | 4 | 34 |
| biomarkers | 2026-07-01 | 1 | 31 |
| overview | 2025-10-01 | 0 | 29 |
| central-sensitization-and-plasticity | 2025-05-01 | 0 | 29 |
| guidelines | 2025-05-01 | 0 | 33 |
| pharmacologic-treatment | 2025-01-07 | 0 | 34 |
| topical-and-interventional-treatment | 2024-12-02 | 0 | 28 |
| peripheral-mechanisms | 2024-10-08 | 0 | 34 |
| sensory-phenotyping-and-qst | 2024-10-02 | 0 | 30 |
| spinal-cord-and-central-neuropathic-pain | 2024-10-01 | 0 | 31 |
| patient-experience-and-advocacy | 2024-09-03 | 0 | 32 |
| red-flags-and-safety-concerns | 2023-12-02 | 0 | 30 |
Recency is not quality: an old paper may be the definitive one, and a new paper may not replicate. Use this to find movement, not to rank evidence. See open questions for what remains unresolved, and the curation log for when these pages were last revised.