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What's new — Neuropathic pain

Generated 2026-09-03 from the publication dates of every paper cited in this condition's pages.

This page answers a different question from the curation log. The log says when we last edited a page; this says how recent the evidence on those pages is — so you can tell settled ground from a field that is actively moving, and jump straight to what has emerged lately.

How much of this condition's evidence is recent

Published within Cited papers
last week 0
last month 0
last 2 months 1
last 3 months 2
last 6 months 2
last year 3
older than a year 285

Counts are cumulative: a paper from last week also counts inside "last month". Dates are PubMed publication or e-publication dates, so a paper may have appeared online before its journal issue.

Newest evidence first

The most recent cited papers, with the pages that use them.

Published Paper Cited on
2026-07-09 PROSPER: a phase III trial of lecithinized superoxide dismutase to prevent oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer — ESMO Gastrointest Oncol ([PMID 42583153](https://pubmed.ncbi.nlm.nih.gov/42583153/){target="_blank" rel="noopener"}) chemotherapy-and-toxic-neuropathy
2026-07-01 New insight into RNA biomarkers in neuropathic pain: a clinician-neuroscientist roadmap to translational testing and treatment monitoring a clinical review — Front Pain Res (Lausanne) ([PMID 42534835](https://pubmed.ncbi.nlm.nih.gov/42534835/){target="_blank" rel="noopener"}) biomarkers
2025-10-01 Prevalence of neuropathic pain following spinal cord injury: An updated systematic review and meta-analysis — J Clin Neurosci ([PMID 41043376](https://pubmed.ncbi.nlm.nih.gov/41043376/){target="_blank" rel="noopener"}) epidemiology-and-burden, overview

Trials — what has moved

16 registered trials are cited by this condition's pages. Registry records were re-checked live when this page was generated, so status, enrolment and results-posting below reflect ClinicalTrials.gov as of that date.

Registry activity Trials
trial records updated in the last week 1
trial records updated in the last month 2
trial records updated in the last 2 months 6
trial records updated in the last 3 months 6
trial records updated in the last 6 months 6
trial records updated in the last year 9

Recently updated registrations

Updated Trial Phase Status N Cited on
2026-09-02 SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropa PHASE2 RECRUITING 190 clinical-trials-landscape, sensory-phenotyping-and-qst
2026-08-04 Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain NA COMPLETED 4 clinical-trials-landscape
2026-07-31 Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain NA RECRUITING 12 clinical-trials-landscape
2026-07-30 A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain PHASE2 COMPLETED 404 clinical-trials-landscape
2026-07-28 Evaluating Laser Photobiomodulation for the Treatment of Neuropathic Pain in Chemotherapy- NA RECRUITING 70 clinical-trials-landscape
2026-07-22 The Effect of Electroacupuncture on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induce NA ACTIVE_NOT_RECRUITING 255 clinical-trials-landscape
2025-12-17 Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury NA RECRUITING 250 clinical-trials-landscape
2025-11-21 Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain NA RECRUITING 30 clinical-trials-landscape
2025-10-14 Neuromodulation as a Treatment for Chemotherapy-Induced Peripheral Neuropathy NA ACTIVE_NOT_RECRUITING 91 clinical-trials-landscape

Posted efficacy and safety results

Trials whose sponsors have posted results to the registry. Adverse-event figures are participant counts summed across all arms as reported — read them against enrolment, and follow the registry link for the arm-by-arm breakdown that determines whether a signal is real.

Results posted Trial Phase N Primary outcome Serious AE Other AE Deaths
2026-07-30 A Study of LY3556050 in Adult Participants With Diabetic Peripheral Ne PHASE2 404 Mean Change From Baseline in Average Pain Intensity (API) as Measured 11 71 1
2023-11-22 Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pai NA 4 Visual Analog Score 2 10 0
2023-09-21 Ricolinostat in Patients With Painful Diabetic Peripheral Neuropathy PHASE2 282 Change in Mean Average Pain Intensity (NRS) 12 58 0
2011-12-08 A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain D PHASE3 220 Duration Adjusted Average Change (DAAC) of Mean Pain Score 19 134 0

10 of these trials are still recruiting or active — see the condition's clinical trials page for the full landscape.

Which pages rest on the newest evidence

🔥 marks a page citing three or more papers from the last year — the pages worth re-reading if you have been away.

Page Newest citation In last year Total citations
chemotherapy-and-toxic-neuropathy 2026-07-09 1 32
biomarkers 2026-07-01 1 31
epidemiology-and-burden 2025-10-01 1 29
overview 2025-10-01 1 29
neuromodulation 2025-09-02 0 30
central-sensitization-and-plasticity 2025-05-01 0 29
clinical-trials-landscape 2025-05-01 0 28
pharmacologic-treatment 2025-01-07 0 34
diabetic-neuropathic-pain 2024-12-07 0 30
topical-and-interventional-treatment 2024-12-02 0 28
peripheral-mechanisms 2024-10-08 0 34
sensory-phenotyping-and-qst 2024-10-02 0 30
spinal-cord-and-central-neuropathic-pain 2024-10-01 0 31
patient-experience-and-advocacy 2024-09-03 0 32
postherpetic-and-postsurgical-pain 2024-09-03 0 31
definition-grading-and-diagnosis 2024-08-05 0 30
guidelines 2024-08-05 0 32
red-flags-and-safety-concerns 2023-12-02 0 30

Recency is not quality: an old paper may be the definitive one, and a new paper may not replicate. Use this to find movement, not to rank evidence. See open questions for what remains unresolved, and the curation log for when these pages were last revised.