Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.

One-paragraph summary

229 trials; pooled NNTs were 6.4 for SNRIs, 7.2 gabapentin, 7.7 pregabalin and 10.6 capsaicin 8%. (PMID 25575710)

Key findings

• 229 trials; pooled NNTs were 6.4 for SNRIs, 7.2 gabapentin, 7.7 pregabalin and 10.6 capsaicin 8%.

Limitations

• Population, follow-up, comparator and outcome definitions constrain generalization.

Why it matters

This paper changed diagnostic, preventive or treatment practice and anchors multiple wiki pages.

Cited by wiki pages

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