What's new — Bipolar disorder¶
Generated 2026-09-03 from the publication dates of every paper cited in this condition's pages.
This page answers a different question from the curation log. The log says when we last edited a page; this says how recent the evidence on those pages is — so you can tell settled ground from a field that is actively moving, and jump straight to what has emerged lately.
How much of this condition's evidence is recent¶
| Published within | Cited papers |
|---|---|
| last week | 0 |
| last month | 0 |
| last 2 months | 5 |
| last 3 months | 5 |
| last 6 months | 10 |
| last year | 19 |
| older than a year | 363 |
Counts are cumulative: a paper from last week also counts inside "last month". Dates are PubMed publication or e-publication dates, so a paper may have appeared online before its journal issue.
Newest evidence first¶
The most recent cited papers, with the pages that use them.
| Published | Paper | Cited on |
|---|---|---|
| 2026-08-03 | Retinal electrophysiology in mood disorders: Toward clinically relevant biomarkers. A systematic review and meta-analysis — J Affect Disord ([PMID 42669383](https://pubmed.ncbi.nlm.nih.gov/42669383/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping |
| 2026-08-02 | Examination of the intersection of bipolar I disorder status and cannabis use disorder severity in relation to health-related quality-of-life and lifetime suicide attempts — J Psychiatr Res ([PMID 42664567](https://pubmed.ncbi.nlm.nih.gov/42664567/){target="_blank" rel="noopener"}) | suicide-mortality-and-physical-health |
| 2026-08-02 | Higher frequencies of CNV deletions in bipolar disorder among Chinese Population — Mol Psychiatry ([PMID 42661060](https://pubmed.ncbi.nlm.nih.gov/42661060/){target="_blank" rel="noopener"}) | genetics-and-neurobiology |
| 2026-08-01 | Risk of heart failure in patients with schizophrenia or bipolar disorder: A systematic review and meta-analysis — Pak J Med Sci ([PMID 42668911](https://pubmed.ncbi.nlm.nih.gov/42668911/){target="_blank" rel="noopener"}) | suicide-mortality-and-physical-health |
| 2026-08-01 | Cause-specific mortality due to physical illness in severe mental disorders in Europe: a population-based multi-country cohort study — Lancet Public Health ([PMID 42480565](https://pubmed.ncbi.nlm.nih.gov/42480565/){target="_blank" rel="noopener"}) | suicide-mortality-and-physical-health |
| 2026-06-02 | Circadian Rhythm Stabilization App to Prevent Mood Episode Recurrence in Patients With Mood Disorders: A Multicenter, Double-Blind, Sham-Controlled, Randomized Clinical Trial — Am J Psychiatry ([PMID 42337416](https://pubmed.ncbi.nlm.nih.gov/42337416/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping, psychotherapy-and-self-management |
| 2026-06-02 | Recommendations for Research and Clinical Implementation of Ambulatory Assessment, Mood Monitoring, Digital Phenotyping, and Remote Measurement Technology in Mood Disorders: Synthesis of Systematic Review Findings — JMIR Ment Health ([PMID 42228842](https://pubmed.ncbi.nlm.nih.gov/42228842/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping |
| 2026-05-09 | Digital phenotyping for predicting relapse in psychiatric disorders: a systematic review of passive sensing approaches — BMC Psychiatry ([PMID 42106724](https://pubmed.ncbi.nlm.nih.gov/42106724/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping |
| 2026-05-02 | White matter microstructure in relatives of people with schizophrenia or bipolar disorder: an ENIGMA meta-analysis — Mol Psychiatry ([PMID 42168580](https://pubmed.ncbi.nlm.nih.gov/42168580/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping |
| 2026-04-03 | The proportion of people with primary affective disorders presenting to early intervention services: systematic review and meta-analysis — Br J Psychiatry ([PMID 42057639](https://pubmed.ncbi.nlm.nih.gov/42057639/){target="_blank" rel="noopener"}) | comorbidity-and-differential-diagnosis |
| 2026-03-02 | The effect of smartphone-based monitoring and treatment including clinical feedback in progressed bipolar disorder: the SmartBipolar trial randomised controlled parallel-group trial — Int J Bipolar Disord ([PMID 41865316](https://pubmed.ncbi.nlm.nih.gov/41865316/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping, psychotherapy-and-self-management |
| 2026-02-01 | Lithium nephrotoxicity: a systematic review and meta-analysis of lithium versus non-lithium control studies in patients with affective disorders — Ther Adv Psychopharmacol ([PMID 41727809](https://pubmed.ncbi.nlm.nih.gov/41727809/){target="_blank" rel="noopener"}) | lithium |
| 2026-01-07 | Mood Monitoring, Mood Tracking, and Ambulatory Assessment Interventions in Depression and Bipolar Disorder: Systematic Review and Meta-Analysis of Randomized Controlled Trials — JMIR Ment Health ([PMID 41499681](https://pubmed.ncbi.nlm.nih.gov/41499681/){target="_blank" rel="noopener"}) | biomarkers-and-digital-phenotyping, psychotherapy-and-self-management |
| 2026-01-02 | Clinical practice guidelines for the management of bipolar disorder: 2025 update — Indian J Psychiatry ([PMID 41694044](https://pubmed.ncbi.nlm.nih.gov/41694044/){target="_blank" rel="noopener"}) | guidelines |
| 2025-12-02 | Mixed features in depressive and bipolar disorders: An updated systematic review — J Affect Disord ([PMID 41448395](https://pubmed.ncbi.nlm.nih.gov/41448395/){target="_blank" rel="noopener"}) | diagnosis-and-bipolar-spectrum |
| 2025-12-01 | Longitudinal associations of electroconvulsive therapy with all-cause mortality and suicide deaths in severe unipolar or bipolar depression: a systematic review and meta-analysis — BMJ Ment Health ([PMID 41407487](https://pubmed.ncbi.nlm.nih.gov/41407487/){target="_blank" rel="noopener"}) | bipolar-depression |
| 2025-11-01 | Occurrence of Psychosis and Bipolar Disorder in Individuals With Attention-Deficit/Hyperactivity Disorder Treated With Stimulants: A Systematic Review and Meta-Analysis — JAMA Psychiatry ([PMID 40900605](https://pubmed.ncbi.nlm.nih.gov/40900605/){target="_blank" rel="noopener"}) | comorbidity-and-differential-diagnosis |
| 2025-10-03 | Meta-analysis of recurrence rate and influencing factors of bipolar disorder — J Affect Disord ([PMID 41176250](https://pubmed.ncbi.nlm.nih.gov/41176250/){target="_blank" rel="noopener"}) | maintenance-and-relapse-prevention |
| 2025-10-01 | The User Experience of Ambulatory Assessment and Mood Monitoring in Bipolar Disorder: Systematic Review and Meta-Synthesis of Qualitative Studies — J Med Internet Res ([PMID 41105870](https://pubmed.ncbi.nlm.nih.gov/41105870/){target="_blank" rel="noopener"}) | patient-experience-and-advocacy |
Trials — what has moved¶
29 registered trials are cited by this condition's pages. Registry records were re-checked live when this page was generated, so status, enrolment and results-posting below reflect ClinicalTrials.gov as of that date.
| Registry activity | Trials |
|---|---|
| trial records updated in the last week | 3 |
| trial records updated in the last month | 11 |
| trial records updated in the last 2 months | 12 |
| trial records updated in the last 3 months | 14 |
| trial records updated in the last 6 months | 19 |
| trial records updated in the last year | 26 |
Recently updated registrations¶
28 of these trials are still recruiting or active — see the condition's clinical trials page for the full landscape.
Which pages rest on the newest evidence¶
🔥 marks a page citing three or more papers from the last year — the pages worth re-reading if you have been away.
| Page | Newest citation | In last year | Total citations |
|---|---|---|---|
| biomarkers-and-digital-phenotyping | 2026-08-03 | 7 | 39 |
| genetics-and-neurobiology | 2026-08-02 | 1 | 25 |
| suicide-mortality-and-physical-health | 2026-08-02 | 3 | 30 |
| psychotherapy-and-self-management | 2026-06-02 | 3 | 28 |
| comorbidity-and-differential-diagnosis | 2026-04-03 | 2 | 27 |
| lithium | 2026-02-01 | 1 | 21 |
| guidelines | 2026-01-02 | 1 | 32 |
| diagnosis-and-bipolar-spectrum | 2025-12-02 | 1 | 31 |
| bipolar-depression | 2025-12-01 | 1 | 24 |
| maintenance-and-relapse-prevention | 2025-10-03 | 1 | 20 |
| patient-experience-and-advocacy | 2025-10-01 | 1 | 23 |
| antidepressant-controversy | 2025-08-07 | 0 | 20 |
| epidemiology-and-course | 2025-08-01 | 0 | 30 |
| mania-and-mixed-states | 2025-08-01 | 0 | 20 |
| pregnancy-and-reproductive-health | 2025-07-01 | 0 | 25 |
| overview | 2025-05-02 | 0 | 30 |
| clinical-trials-landscape | 2024-06-03 | 0 | 18 |
| red-flags-and-safety-concerns | 2024-06-03 | 0 | 30 |
Recency is not quality: an old paper may be the definitive one, and a new paper may not replicate. Use this to find movement, not to rank evidence. See open questions for what remains unresolved, and the curation log for when these pages were last revised.