Depression — master bibliography

Last updated: 2026-08-30. Every PMID below was retrieved through live PubMed E-utilities in this build session. “Cited by” lists the principal pages; repeated citations may occur elsewhere.

Diagnosis, epidemiology, burden, and experience

• Uher R, et al. Major depressive disorder in DSM-5: implications for clinical practice and research of changes from DSM-IV. Depression and Anxiety. 2014. PMID 24272961 — tags: [diagnosis, DSM] — cited by: diagnostic-criteria-and-heterogeneity.md
• Kennedy SH. Unpacking Major Depressive Disorder: From Classification to Treatment Selection. Canadian Journal of Psychiatry. 2018. PMID 29278937 — tags: [diagnosis, heterogeneity] — cited by: diagnostic-criteria-and-heterogeneity.md
• Fried EI, et al. Depression is not a consistent syndrome: An investigation of unique symptom patterns in STAR*D. Journal of Affective Disorders. 2015. PMID 25451401 — tags: [heterogeneity, symptoms] — cited by: OPEN-QUESTIONS.md, STATISTICS.md, diagnostic-criteria-and-heterogeneity.md
• Hasin DS, et al. Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States. JAMA Psychiatry. 2018. PMID 29450462 — tags: [epidemiology, specifiers] — cited by: STATISTICS.md, diagnostic-criteria-and-heterogeneity.md, epidemiology-and-burden.md, overview.md, red-flags-and-safety-concerns.md
• Gutiérrez-Rojas L, et al. Prevalence and correlates of major depressive disorder: a systematic review. Revista Brasileira de Psiquiatria. 2020. PMID 32756809 — tags: [prevalence] — cited by: epidemiology-and-burden.md
• GBD 2019 Mental Disorders Collaborators. Global burden of 12 mental disorders, 1990–2019. Lancet Psychiatry. 2022. PMID 35026139 — tags: [GBD, DALY] — cited by: OPEN-QUESTIONS.md, STATISTICS.md, epidemiology-and-burden.md, overview.md, suicide-risk-and-mortality.md
• Thornicroft G, et al. Undertreatment of people with major depressive disorder in 21 countries. British Journal of Psychiatry. 2017. PMID 27908899 — tags: [treatment-gap, global] — cited by: OPEN-QUESTIONS.md, epidemiology-and-burden.md, guidelines.md, overview.md, sources.md, themes.md
• Greenberg PE, et al. The Economic Burden of Adults with MDD in the United States (2010 and 2018). PharmacoEconomics. 2021. PMID 33950419 — tags: [economic-burden, US] — cited by: STATISTICS.md, epidemiology-and-burden.md
• Greenberg P, et al. The Economic Burden of Adults with MDD in the United States (2019). Advances in Therapy. 2023. PMID 37518849 — tags: [economic-burden] — cited by: epidemiology-and-burden.md
• Zhdanava M, et al. Prevalence and National Burden of TRD and MDD in the United States. Journal of Clinical Psychiatry. 2021. PMID 33989464 — tags: [TRD, burden] — cited by: epidemiology-and-burden.md
• Walker ER, et al. Mortality in mental disorders and global disease burden implications. JAMA Psychiatry. 2015. PMID 25671328 — tags: [mortality] — cited by: OPEN-QUESTIONS.md, epidemiology-and-burden.md, overview.md, suicide-risk-and-mortality.md
• Kerr C, et al. The lived experience of major and treatment-resistant depression in England. Acta Psychologica. 2023. PMID 37734244 — tags: [patient-voice, TRD] — cited by: OPEN-QUESTIONS.md, patient-experience-and-advocacy.md, sources.md, themes.md
• Cuijpers P. The patient perspective in research on major depression. BMC Psychiatry. 2011. PMID 21592336 — tags: [patient-voice, research] — cited by: patient-experience-and-advocacy.md, sources.md, themes.md
• Mancini M, et al. Major Depression as a Disorder of the Narrative Self: A Qualitative Study. 2024. PMID 38776880 — tags: [patient-voice, identity] — cited by: patient-experience-and-advocacy.md, sources.md, themes.md
• Alva G, et al. Importance of achieving rapid treatment response in major depressive disorder. CNS Spectrums. 2023. PMID 36967225 — tags: [rapid-response, function] — cited by: patient-experience-and-advocacy.md
• Nussbaum AM. Questionable Agreement: The Experience of Depression and DSM-5 MDD Criteria. Journal of Medicine and Philosophy. 2020. PMID 33206179 — tags: [patient-voice, diagnosis] — cited by: patient-experience-and-advocacy.md
• Sheehan DV, et al. Restoring function in major depressive disorder: A systematic review. Journal of Affective Disorders. 2017. PMID 28364701 — tags: [function, outcomes] — cited by: patient-experience-and-advocacy.md
• Franzsen D, et al. A conceptual framework for return to work for clients with MDD. Work. 2023. PMID 36214009 — tags: [work, recovery] — cited by: patient-experience-and-advocacy.md
• dosReis S, et al. Preferences for Treatments for MDD: Formative Qualitative Research. The Patient. 2023. PMID 36121615 — tags: [preferences, qualitative] — cited by: patient-experience-and-advocacy.md
• Crawford J, et al. Shared decision-making and implementation of treatment recommendations for depression. Patient Education and Counseling. 2021. PMID 33563500 — tags: [shared-decisions] — cited by: patient-experience-and-advocacy.md
• Liu J, et al. Temporal and spatial trend analysis of all-cause depression burden based on GBD 2019. Scientific Reports. 2024. PMID 38811645 — tags: [burden, trends] — cited by: epidemiology-and-burden.md

Mechanisms and genetics

• Delgado PL. Depression: the case for a monoamine deficiency. Journal of Clinical Psychiatry. 2000. PMID 10775018 — tags: [monoamine] — cited by: neurobiology-and-mechanisms.md
• Moncrieff J, et al. The serotonin theory of depression: a systematic umbrella review. Molecular Psychiatry. 2023. PMID 35854107 — tags: [serotonin, controversy] — cited by: neurobiology-and-mechanisms.md, overview.md
• Dean J, Keshavan M. The neurobiology of depression: An integrated view. Asian Journal of Psychiatry. 2017. PMID 28558878 — tags: [mechanisms] — cited by: neurobiology-and-mechanisms.md
• Troubat R, et al. Neuroinflammation and depression: A review. European Journal of Neuroscience. 2021. PMID 32150310 — tags: [inflammation] — cited by: neurobiology-and-mechanisms.md
• Zhang JC, et al. BDNF-TrkB signaling in inflammation-related depression. Current Neuropharmacology. 2016. PMID 26786147 — tags: [BDNF, plasticity] — cited by: neurobiology-and-mechanisms.md
• Zajkowska Z, et al. Cortisol and development of depression in adolescence and young adulthood. Psychoneuroendocrinology. 2022. PMID 34920399 — tags: [HPA, cortisol] — cited by: neurobiology-and-mechanisms.md
• Fernandes BS, et al. Insulin resistance in depression: A large meta-analysis. Neuroscience and Biobehavioral Reviews. 2022. PMID 35777578 — tags: [metabolic] — cited by: biomarkers-and-treatment-prediction.md, neurobiology-and-mechanisms.md
• Howard DM, et al. Genome-wide meta-analysis of depression identifies 102 independent variants. Nature Neuroscience. 2019. PMID 30718901 — tags: [GWAS, genetics] — cited by: OPEN-QUESTIONS.md, biomarkers-and-treatment-prediction.md, diagnostic-criteria-and-heterogeneity.md, genetics.md, neurobiology-and-mechanisms.md, overview.md
• Kendall KM, et al. The genetic basis of major depression. Psychological Medicine. 2021. PMID 33682643 — tags: [genetics, review] — cited by: genetics.md
• Flint J, Kendler KS. The genetic basis of major depressive disorder. Molecular Psychiatry. 2023. PMID 36702864 — tags: [genetics, review] — cited by: OPEN-QUESTIONS.md, genetics.md
• Otte C, et al. Major depressive disorder. Nature Reviews Disease Primers. 2016. PMID 27629598 — tags: [overview, heritability] — cited by: genetics.md
• Yuan M, et al. Epigenetic regulation in major depression and stress-related disorders. Signal Transduction and Targeted Therapy. 2023. PMID 37644009 — tags: [epigenetics] — cited by: genetics.md
• Cross-Disorder Group of the Psychiatric Genomics Consortium. Shared risk loci across five psychiatric disorders. Lancet. 2013. PMID 23453885 — tags: [cross-disorder, GWAS] — cited by: genetics.md, neurobiology-and-mechanisms.md

Conventional treatments and efficacy debate

• Cipriani A, et al. Comparative efficacy and acceptability of 21 antidepressant drugs. Lancet. 2018. PMID 29477251 — tags: [antidepressants, network-meta-analysis] — cited by: OPEN-QUESTIONS.md, STATISTICS.md, antidepressant-pharmacology.md, overview.md, psychotherapy-and-combination.md, red-flags-and-safety-concerns.md, the-efficacy-debate.md
• Turner EH, et al. Selective publication of antidepressant trials. New England Journal of Medicine. 2008. PMID 18199864 — tags: [publication-bias, FDA] — cited by: STATISTICS.md, overview.md, the-efficacy-debate.md
• Kirsch I, et al. Initial severity and antidepressant benefits. PLoS Medicine. 2008. PMID 18303940 — tags: [severity, FDA] — cited by: OPEN-QUESTIONS.md, overview.md, the-efficacy-debate.md
• Fournier JC, et al. Antidepressant drug effects and depression severity. JAMA. 2010. PMID 20051569 — tags: [severity, individual-data] — cited by: OPEN-QUESTIONS.md, overview.md, the-efficacy-debate.md
• Geddes JR, et al. Relapse prevention with antidepressant treatment. Lancet. 2003. PMID 12606176 — tags: [maintenance, relapse] — cited by: STATISTICS.md, antidepressant-pharmacology.md, overview.md, the-efficacy-debate.md
• Kishi T, et al. Antidepressants in the maintenance phase. Molecular Psychiatry. 2023. PMID 36253442 — tags: [maintenance] — cited by: antidepressant-pharmacology.md
• Henssler J, et al. Combining antidepressants versus monotherapy. JAMA Psychiatry. 2022. PMID 35171215 — tags: [combination] — cited by: antidepressant-pharmacology.md, patient-experience-and-advocacy.md, treatment-resistant-depression.md
• Davies J, Read J. Incidence, severity and duration of antidepressant withdrawal effects. Addictive Behaviors. 2019. PMID 30292574 — tags: [withdrawal] — cited by: OPEN-QUESTIONS.md, antidepressant-pharmacology.md, guidelines.md, red-flags-and-safety-concerns.md, sources.md, themes.md
• Rothmore J. Antidepressant-induced sexual dysfunction. Medical Journal of Australia. 2020. PMID 32172535 — tags: [sexual-function, adverse-effects] — cited by: antidepressant-pharmacology.md, red-flags-and-safety-concerns.md, sources.md, themes.md
• Cuijpers P, et al. Psychotherapies, pharmacotherapies and their combination. World Psychiatry. 2020. PMID 31922679 — tags: [psychotherapy, combination] — cited by: OPEN-QUESTIONS.md, STATISTICS.md, overview.md, psychotherapy-and-combination.md, the-efficacy-debate.md
• Cuijpers P, et al. Psychotherapies for depression: network meta-analysis. World Psychiatry. 2021. PMID 34002502 — tags: [psychotherapy] — cited by: psychotherapy-and-combination.md
• Ciharova M, et al. Cognitive restructuring, behavioral activation and CBT. Journal of Consulting and Clinical Psychology. 2021. PMID 34264703 — tags: [CBT, behavioral-activation] — cited by: OPEN-QUESTIONS.md, psychotherapy-and-combination.md
• Uphoff E, et al. Behavioural activation therapy for depression in adults. Cochrane Database of Systematic Reviews. 2020. PMID 32628293 — tags: [behavioral-activation] — cited by: psychotherapy-and-combination.md
• DeRubeis RJ, et al. Cognitive therapy versus medications in moderate-to-severe depression. Archives of General Psychiatry. 2005. PMID 15809408 — tags: [CBT, comparative] — cited by: psychotherapy-and-combination.md
• Guidi J, et al. Sequential combination of pharmacotherapy and psychotherapy. JAMA Psychiatry. 2021. PMID 33237285 — tags: [sequential, relapse] — cited by: psychotherapy-and-combination.md
• Furukawa TA, et al. Dismantling, optimising, and personalising internet CBT for depression. Lancet Psychiatry. 2021. PMID 33957075 — tags: [digital-CBT] — cited by: OPEN-QUESTIONS.md, psychotherapy-and-combination.md
• Guo T, et al. Measurement-Based Care Versus Standard Care for Major Depression. American Journal of Psychiatry. 2015. PMID 26315978 — tags: [measurement-based-care] — cited by: OPEN-QUESTIONS.md, diagnostic-criteria-and-heterogeneity.md, epidemiology-and-burden.md, overview.md, patient-experience-and-advocacy.md, psychotherapy-and-combination.md
• Yin J, et al. Escitalopram versus other antidepressive agents for MDD. BMC Psychiatry. 2023. PMID 38001423 — tags: [escitalopram] — cited by: antidepressant-pharmacology.md
• Oliva V, et al. Gastrointestinal side effects associated with antidepressant treatments. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2021. PMID 33549697 — tags: [adverse-effects] — cited by: antidepressant-pharmacology.md
• Marks S. Antidepressants, sexual side-effects, post-SSRI sexual dysfunction, and serotonin syndrome. British Journal of Nursing. 2023. PMID 37495413 — tags: [safety, sexual-function] — cited by: antidepressant-pharmacology.md, red-flags-and-safety-concerns.md
• Oliva V, et al. Pharmacological treatments for psychotic depression. Lancet Psychiatry. 2024. PMID 38360024 — tags: [psychotic-depression] — cited by: diagnostic-criteria-and-heterogeneity.md, red-flags-and-safety-concerns.md, the-efficacy-debate.md
• Noetel M, et al. Effect of exercise for depression. BMJ. 2024. PMID 38355154 — tags: [exercise, network-meta-analysis] — cited by: psychotherapy-and-combination.md

Resistant and rapid-acting treatment

• Rush AJ, et al. Acute and longer-term outcomes in STAR*D. American Journal of Psychiatry. 2006. PMID 17074942 — tags: [STAR-D, sequencing] — cited by: OPEN-QUESTIONS.md, STATISTICS.md, antidepressant-pharmacology.md, overview.md, the-efficacy-debate.md, themes.md, treatment-resistant-depression.md
• Pigott HE, et al. Reanalysis of STAR*D with fidelity to the protocol. BMJ Open. 2023. PMID 37491091 — tags: [STAR-D, controversy] — cited by: OPEN-QUESTIONS.md, STATISTICS.md, antidepressant-pharmacology.md, overview.md, the-efficacy-debate.md, themes.md, treatment-resistant-depression.md
• Gaynes BN, et al. Defining treatment-resistant depression. Depression and Anxiety. 2020. PMID 31638723 — tags: [TRD, definition] — cited by: treatment-resistant-depression.md
• Sforzini L, et al. Consensus guideline for definition of TRD in trials. Molecular Psychiatry. 2022. PMID 34907394 — tags: [TRD, definition] — cited by: treatment-resistant-depression.md
• Nuñez NA, et al. Augmentation strategies for treatment-resistant major depression. Journal of Affective Disorders. 2022. PMID 34986373 — tags: [augmentation, TRD] — cited by: OPEN-QUESTIONS.md, treatment-resistant-depression.md
• McAllister-Williams RH, et al. Difficult-to-treat depression: international consensus statement. Journal of Affective Disorders. 2020. PMID 32217227 — tags: [difficult-to-treat] — cited by: treatment-resistant-depression.md
• Scott F, et al. Augmentation and combination treatments for early-stage TRD. Journal of Psychopharmacology. 2023. PMID 35861202 — tags: [TRD, augmentation] — cited by: OPEN-QUESTIONS.md, treatment-resistant-depression.md
• Vázquez GH, et al. Antidepressants plus antipsychotics versus esketamine versus lithium. Journal of Psychopharmacology. 2021. PMID 34238049 — tags: [TRD, comparative] — cited by: treatment-resistant-depression.md
• Berman RM, et al. Antidepressant effects of ketamine. Biological Psychiatry. 2000. PMID 10686270 — tags: [ketamine, landmark] — cited by: OPEN-QUESTIONS.md, clinical-trials-landscape.md, ketamine-and-glutamatergic-agents.md, neurobiology-and-mechanisms.md, overview.md
• Zarate CA Jr, et al. A randomized trial of an NMDA antagonist in TRD. Archives of General Psychiatry. 2006. PMID 16894061 — tags: [ketamine, RCT] — cited by: OPEN-QUESTIONS.md, clinical-trials-landscape.md, ketamine-and-glutamatergic-agents.md, neurobiology-and-mechanisms.md, overview.md
• Popova V, et al. Esketamine nasal spray plus oral antidepressant in TRD. American Journal of Psychiatry. 2019. PMID 31109201 — tags: [esketamine, phase-3] — cited by: STATISTICS.md, clinical-trials-landscape.md, ketamine-and-glutamatergic-agents.md, overview.md, treatment-resistant-depression.md
• Daly EJ, et al. Esketamine plus oral antidepressant for relapse prevention. JAMA Psychiatry. 2019. PMID 31166571 — tags: [esketamine, maintenance] — cited by: OPEN-QUESTIONS.md, ketamine-and-glutamatergic-agents.md, treatment-resistant-depression.md
• Phillips JL, et al. Single, repeated, and maintenance ketamine infusions for TRD. American Journal of Psychiatry. 2019. PMID 30922101 — tags: [ketamine, maintenance] — cited by: OPEN-QUESTIONS.md, ketamine-and-glutamatergic-agents.md
• Bahji A, et al. Comparative efficacy of racemic ketamine and esketamine. Journal of Affective Disorders. 2021. PMID 33022440 — tags: [ketamine, esketamine] — cited by: clinical-trials-landscape.md, ketamine-and-glutamatergic-agents.md
• Dean RL, et al. Ketamine and other glutamate receptor modulators for depression. Cochrane Database of Systematic Reviews. 2021. PMID 34510411 — tags: [ketamine, systematic-review] — cited by: ketamine-and-glutamatergic-agents.md, the-efficacy-debate.md
• Iosifescu DV, et al. Dextromethorphan-bupropion in MDD: GEMINI. Journal of Clinical Psychiatry. 2022. PMID 35649167 — tags: [dextromethorphan, phase-3] — cited by: ketamine-and-glutamatergic-agents.md, overview.md, psychedelics-and-novel-therapeutics.md
• Tabuteau H, et al. Effect of dextromethorphan-bupropion in MDD. American Journal of Psychiatry. 2022. PMID 35582785 — tags: [dextromethorphan] — cited by: ketamine-and-glutamatergic-agents.md
• Wilkinson ST, et al. Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial. Psychotherapy and Psychosomatics. 2021;90:318-327. PMID 34186531 — tags: [ketamine, psychotherapy, maintenance] — cited by: OPEN-QUESTIONS.md, ketamine-and-glutamatergic-agents.md, psychotherapy-and-combination.md
• Wilkinson ST, et al. Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial. Journal of Clinical Psychiatry. 2026;87:25m16285. PMID 42095692 — tags: [esketamine, psychotherapy, suicidality] — cited by: OPEN-QUESTIONS.md, ketamine-and-glutamatergic-agents.md, psychotherapy-and-combination.md

Neuromodulation and psychedelics

• UK ECT Review Group. Efficacy and safety of ECT in depressive disorders. Lancet. 2003. PMID 12642045 — tags: [ECT, meta-analysis] — cited by: STATISTICS.md, neuromodulation.md, overview.md
• Jelovac A, et al. Relapse following successful ECT for major depression. Neuropsychopharmacology. 2013. PMID 23774532 — tags: [ECT, relapse] — cited by: OPEN-QUESTIONS.md, neuromodulation.md
• van Diermen L, et al. Prediction of ECT response and remission. British Journal of Psychiatry. 2018. PMID 29436330 — tags: [ECT, prediction] — cited by: neuromodulation.md
• Lambrichts S, et al. Does lithium prevent relapse following successful ECT? Acta Psychiatrica Scandinavica. 2021. PMID 33506961 — tags: [ECT, lithium] — cited by: OPEN-QUESTIONS.md, neuromodulation.md
• O'Reardon JP, et al. TMS in acute major depression: multisite RCT. Biological Psychiatry. 2007. PMID 17573044 — tags: [TMS, RCT] — cited by: neuromodulation.md
• Mutz J, et al. Non-surgical brain stimulation for major depressive episodes. BMJ. 2019. PMID 30917990 — tags: [neuromodulation, NMA] — cited by: neurobiology-and-mechanisms.md, neuromodulation.md
• Chu HT, et al. Theta-burst stimulation for major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2021. PMID 33166668 — tags: [TBS] — cited by: neuromodulation.md
• Sabé M, et al. TMS and tDCS across mental disorders. JAMA Network Open. 2024. PMID 38776083 — tags: [TMS, tDCS] — cited by: neuromodulation.md
• Conway CR, et al. Vagus nerve stimulation in TRD: one-year sham-controlled trial. Brain Stimulation. 2025. PMID 39706521 — tags: [VNS, TRD] — cited by: neuromodulation.md
• Cole EJ, et al. Stanford Accelerated Intelligent Neuromodulation Therapy. American Journal of Psychiatry. 2020. PMID 32252538 — tags: [SNT, open-label] — cited by: neuromodulation.md, overview.md
• Cole EJ, et al. Stanford Neuromodulation Therapy: double-blind RCT. American Journal of Psychiatry. 2022. PMID 34711062 — tags: [SNT, RCT] — cited by: OPEN-QUESTIONS.md, clinical-trials-landscape.md, neuromodulation.md, overview.md
• Anand A, et al. Ketamine versus ECT for nonpsychotic TRD. New England Journal of Medicine. 2023. PMID 37224232 — tags: [ECT, ketamine] — cited by: ketamine-and-glutamatergic-agents.md, neuromodulation.md, treatment-resistant-depression.md
• Pedraz-Petrozzi B, et al. Baseline inflammatory profiles in moderate-to-severe depression and differential response to intermittent theta-burst stimulation. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2026;148:111814. PMID 42364721 — tags: [iTBS, inflammation, prediction] — cited by: OPEN-QUESTIONS.md, biomarkers-and-treatment-prediction.md, neuromodulation.md
• Carhart-Harris R, et al. Trial of psilocybin versus escitalopram. New England Journal of Medicine. 2021. PMID 33852780 — tags: [psilocybin, RCT] — cited by: OPEN-QUESTIONS.md, clinical-trials-landscape.md, overview.md, psychedelics-and-novel-therapeutics.md
• Goodwin GM, et al. Single-dose psilocybin for TRD. New England Journal of Medicine. 2022. PMID 36322843 — tags: [psilocybin, TRD] — cited by: OPEN-QUESTIONS.md, clinical-trials-landscape.md, psychedelics-and-novel-therapeutics.md
• Raison CL, et al. Single-dose psilocybin for MDD. JAMA. 2023. PMID 37651119 — tags: [psilocybin, MDD] — cited by: psychedelics-and-novel-therapeutics.md
• Davis AK, et al. Effects of psilocybin-assisted therapy on MDD. JAMA Psychiatry. 2021. PMID 33146667 — tags: [psilocybin, RCT] — cited by: psychedelics-and-novel-therapeutics.md
• Haikazian S, et al. Psilocybin-assisted therapy for depression: systematic review. Psychiatry Research. 2023. PMID 37844352 — tags: [psilocybin, meta-analysis] — cited by: psychedelics-and-novel-therapeutics.md
• Metaxa AM, Clarke M. Efficacy of psilocybin for depression. BMJ. 2024. PMID 38692686 — tags: [psilocybin, meta-analysis] — cited by: psychedelics-and-novel-therapeutics.md
• Clayton AH, et al. Zuranolone for adults with MDD. American Journal of Psychiatry. 2023. PMID 37132201 — tags: [zuranolone, neurosteroid] — cited by: psychedelics-and-novel-therapeutics.md
• Hinkle JT, et al. Adverse events in studies of classic psychedelics. JAMA Psychiatry. 2024. PMID 39230883 — tags: [psychedelics, safety] — cited by: psychedelics-and-novel-therapeutics.md, red-flags-and-safety-concerns.md

Biomarkers, safety, and guidelines

• Kennis M, et al. Prospective biomarkers of MDD. Molecular Psychiatry. 2020. PMID 31745238 — tags: [biomarkers, validation] — cited by: OPEN-QUESTIONS.md, biomarkers-and-treatment-prediction.md, diagnostic-criteria-and-heterogeneity.md
• Dunlop BW, Mayberg HS. Prediction of treatment outcomes in MDD. Expert Review of Clinical Pharmacology. 2015. PMID 26289221 — tags: [prediction] — cited by: biomarkers-and-treatment-prediction.md
• Olbrich S, et al. EEG biomarkers in MDD. International Review of Psychiatry. 2013. PMID 24151805 — tags: [EEG, prediction] — cited by: biomarkers-and-treatment-prediction.md
• Tomasik J, et al. Metabolomic Biomarker Signatures for Bipolar and Unipolar Depression. JAMA Psychiatry. 2024. PMID 37878349 — tags: [metabolomics, differential] — cited by: biomarkers-and-treatment-prediction.md
• Liu JJ, et al. Peripheral cytokine levels and antidepressant response. Molecular Psychiatry. 2020. PMID 31427752 — tags: [cytokines, prediction] — cited by: OPEN-QUESTIONS.md, biomarkers-and-treatment-prediction.md, neurobiology-and-mechanisms.md
• Oslin DW, et al. PRIME Care pharmacogenomic randomized trial. JAMA. 2022. PMID 35819423 — tags: [pharmacogenomics] — cited by: biomarkers-and-treatment-prediction.md, genetics.md
• Li X, et al. Predictors of suicidal ideation, attempt and death in MDD. Journal of Affective Disorders. 2022. PMID 35101521 — tags: [suicide, prediction] — cited by: OPEN-QUESTIONS.md, biomarkers-and-treatment-prediction.md, red-flags-and-safety-concerns.md, suicide-risk-and-mortality.md
• Docherty AR, et al. GWAS meta-analysis of suicide attempt. American Journal of Psychiatry. 2023. PMID 37777856 — tags: [suicide, genetics] — cited by: genetics.md, suicide-risk-and-mortality.md
• Brenner P, et al. Excess deaths in treatment-resistant depression. Therapeutic Advances in Psychopharmacology. 2021. PMID 33912340 — tags: [TRD, mortality] — cited by: suicide-risk-and-mortality.md
• Le GH, et al. Cognitive functioning and suicidal outcomes across severe mental disorders. Psychological Medicine. 2024. PMID 39168166 — tags: [suicide, cognition] — cited by: suicide-risk-and-mortality.md
• Lam RW, et al. CANMAT 2023 update for adult MDD. Canadian Journal of Psychiatry. 2024. PMID 38711351 — tags: [guideline, CANMAT] — cited by: REGISTRY.md, guidelines.md, overview.md
• McQuaid JR, et al. Synopsis of the 2022 VA/DoD MDD guideline. Annals of Internal Medicine. 2022. PMID 36122380 — tags: [guideline, VA-DoD] — cited by: REGISTRY.md, guidelines.md
• Qaseem A, et al. ACP living guideline for acute adult MDD. Annals of Internal Medicine. 2023. PMID 36689752 — tags: [guideline, ACP] — cited by: REGISTRY.md, guidelines.md
• Marx W, et al. Lifestyle-based care guideline for MDD. World Journal of Biological Psychiatry. 2023. PMID 36202135 — tags: [guideline, lifestyle] — cited by: REGISTRY.md, guidelines.md, psychotherapy-and-combination.md
• Swainson J, et al. CANMAT recommendations for racemic ketamine. Canadian Journal of Psychiatry. 2021. PMID 33174760 — tags: [guideline, ketamine] — cited by: REGISTRY.md, guidelines.md
• McClintock SM, et al. Consensus recommendations for clinical rTMS. Journal of Clinical Psychiatry. 2018. PMID 28541649 — tags: [guideline, TMS] — cited by: REGISTRY.md, guidelines.md
• Hirschfeld RM. Differential diagnosis of bipolar disorder and MDD. Journal of Affective Disorders. 2014. PMID 25533909 — tags: [bipolar, differential] — cited by: diagnostic-criteria-and-heterogeneity.md, red-flags-and-safety-concerns.md

Deepening sweep — 2026-08-30

• Austin MP, et al. Lithium augmentation in antidepressant-resistant patients. A quantitative analysis. The British journal of psychiatry : the journal of mental science. 1991;159:510-4. PMID 1836411 — tags: [treatment-resistant-depression] — cited by: treatment-resistant-depression.md
• Bauer M, et al. Lithium augmentation in treatment-resistant depression: meta-analysis of placebo-controlled studies. Journal of clinical psychopharmacology. 1999;19:427-34. PMID 10505584 — tags: [treatment-resistant-depression] — cited by: treatment-resistant-depression.md
• Judd LL, et al. Delineating the longitudinal structure of depressive illness: beyond clinical subtypes and duration thresholds. Pharmacopsychiatry. 2000;33:3-7. PMID 10721877 — tags: [epidemiology-and-burden] — cited by: epidemiology-and-burden.md
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