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What's new — Retinoblastoma

Generated 2026-09-03 from the publication dates of every paper cited in this condition's pages.

This page answers a different question from the curation log. The log says when we last edited a page; this says how recent the evidence on those pages is — so you can tell settled ground from a field that is actively moving, and jump straight to what has emerged lately.

How much of this condition's evidence is recent

Published within Cited papers
last week 0
last month 0
last 2 months 1
last 3 months 4
last 6 months 5
last year 18
older than a year 349

Counts are cumulative: a paper from last week also counts inside "last month". Dates are PubMed publication or e-publication dates, so a paper may have appeared online before its journal issue.

Newest evidence first

The most recent cited papers, with the pages that use them.

Published Paper Cited on
2026-08-03 Intra-arterial chemotherapy for retinoblastoma: a structured narrative review — World J Pediatr Surg ([PMID 42553724](https://pubmed.ncbi.nlm.nih.gov/42553724/){target="_blank" rel="noopener"}) intra-arterial-chemotherapy
2026-07-03 Multimodal Imaging of Optic Nerve Invasion in Unilateral Retinoblastoma — Ophthalmology ([PMID 42397330](https://pubmed.ncbi.nlm.nih.gov/42397330/){target="_blank" rel="noopener"}) enucleation-and-high-risk-pathology
2026-07-02 Retinoblastoma presenting as congenital glaucoma — BMJ Case Rep ([PMID 42486661](https://pubmed.ncbi.nlm.nih.gov/42486661/){target="_blank" rel="noopener"}) classification-and-staging
2026-07-01 Global retinoblastoma service availability in 2024 and equity trends since 2017 — Br J Ophthalmol ([PMID 42463304](https://pubmed.ncbi.nlm.nih.gov/42463304/){target="_blank" rel="noopener"}) global-access-and-outcome-disparity, systemic-chemotherapy
2026-05-01 Abemaciclib Inhibits Retinoblastoma Tumor Growth by Targeting CDK1/2 — Invest Ophthalmol Vis Sci ([PMID 42212883](https://pubmed.ncbi.nlm.nih.gov/42212883/){target="_blank" rel="noopener"}) molecular-pathogenesis-and-cell-of-origin
2026-02-01 Intravenous chemotherapy versus intra-arterial chemotherapy for retinoblastoma — Cochrane Database Syst Rev ([PMID 41700592](https://pubmed.ncbi.nlm.nih.gov/41700592/){target="_blank" rel="noopener"}) intra-arterial-chemotherapy
2026-01-01 A bird's eye view on potential molecular prognostic markers in retinoblastoma: insights for precision oncology — Ophthalmic Genet ([PMID 41542805](https://pubmed.ncbi.nlm.nih.gov/41542805/){target="_blank" rel="noopener"}) intravitreal-and-intracameral-chemotherapy, molecular-pathogenesis-and-cell-of-origin
2026-01-01 The utility of aqueous humor liquid biopsy in retinoblastoma genetic analysis: a systematic review of concordance and influencing factors — Ophthalmic Genet ([PMID 41521223](https://pubmed.ncbi.nlm.nih.gov/41521223/){target="_blank" rel="noopener"}) intravitreal-and-intracameral-chemotherapy, molecular-pathogenesis-and-cell-of-origin
2025-12-02 Adjuvant Chemotherapy in Retinoblastoma with Postlaminar Optic Nerve Invasion: A Global Multicenter Study — Ophthalmol Retina ([PMID 41475682](https://pubmed.ncbi.nlm.nih.gov/41475682/){target="_blank" rel="noopener"}) enucleation-and-high-risk-pathology
2025-12-01 Retinoblastoma management in China: clinical challenges — Int J Ophthalmol ([PMID 41280625](https://pubmed.ncbi.nlm.nih.gov/41280625/){target="_blank" rel="noopener"}) clinical-presentation-and-diagnosis, global-access-and-outcome-disparity, red-flags-and-safety-concerns, vision-outcomes-and-patient-experience
2025-11-11 [The efficacy of topotecan versus topotecan combined with melphalan in the treatment of vitreous seeds in retinoblastoma] — Zhonghua Yan Ke Za Zhi ([PMID 41218901](https://pubmed.ncbi.nlm.nih.gov/41218901/){target="_blank" rel="noopener"}) intravitreal-and-intracameral-chemotherapy
2025-11-03 GD2-CAR-Engineered Microglia Exhibit Antitumor Effects in Organoids and Animal Models of Retinoblastoma — Invest Ophthalmol Vis Sci ([PMID 41230904](https://pubmed.ncbi.nlm.nih.gov/41230904/){target="_blank" rel="noopener"}) vision-outcomes-and-patient-experience
2025-11-02 Diffuse infiltrating retinoblastoma: a multicentre, international, data-sharing study — Br J Ophthalmol ([PMID 40738737](https://pubmed.ncbi.nlm.nih.gov/40738737/){target="_blank" rel="noopener"}) classification-and-staging, systemic-chemotherapy
2025-11-01 Orbital myiasis in neglected orbital retinoblastoma — Natl Med J India ([PMID 41645972](https://pubmed.ncbi.nlm.nih.gov/41645972/){target="_blank" rel="noopener"}) clinical-presentation-and-diagnosis, global-access-and-outcome-disparity, red-flags-and-safety-concerns
2025-10-02 High-risk features in retinoblastoma: the association between histopathology and MRI — BMJ Open Ophthalmol ([PMID 41043969](https://pubmed.ncbi.nlm.nih.gov/41043969/){target="_blank" rel="noopener"}) enucleation-and-high-risk-pathology
2025-10-02 Intra-arterial chemotherapy for retinoblastoma: a performance analysis — Br J Ophthalmol ([PMID 40541288](https://pubmed.ncbi.nlm.nih.gov/40541288/){target="_blank" rel="noopener"}) clinical-trials-landscape, intra-arterial-chemotherapy, systemic-chemotherapy
2025-10-01 Spatial Proteomic Analysis Highlights Molecular Reprogramming in Optic Nerve Invasive Retinoblastoma — Invest Ophthalmol Vis Sci ([PMID 41129126](https://pubmed.ncbi.nlm.nih.gov/41129126/){target="_blank" rel="noopener"}) enucleation-and-high-risk-pathology
2025-09-09 Outcomes and adverse events following intra-arterial chemotherapy for retinoblastoma: A single center study in South India — World J Clin Pediatr ([PMID 40881098](https://pubmed.ncbi.nlm.nih.gov/40881098/){target="_blank" rel="noopener"}) intra-arterial-chemotherapy

Trials — what has moved

11 registered trials are cited by this condition's pages. Registry records were re-checked live when this page was generated, so status, enrolment and results-posting below reflect ClinicalTrials.gov as of that date.

Registry activity Trials
trial records updated in the last week 0
trial records updated in the last month 1
trial records updated in the last 2 months 1
trial records updated in the last 3 months 1
trial records updated in the last 6 months 1
trial records updated in the last year 3

Recently updated registrations

Updated Trial Phase Status N Cited on
2026-08-25 A Study to Give Treatment Inside the Eye to Treat Retinoblastoma PHASE2 RECRUITING 26 clinical-trials-landscape
2025-11-28 Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategi PHASE2, PHASE3 RECRUITING 225 clinical-trials-landscape
2025-09-19 Studying Health Outcomes After Treatment in Patients With Retinoblastoma NA RECRUITING 900 clinical-trials-landscape

Posted efficacy and safety results

Trials whose sponsors have posted results to the registry. Adverse-event figures are participant counts summed across all arms as reported — read them against enrolment, and follow the registry link for the arm-by-arm breakdown that determines whether a signal is real.

Results posted Trial Phase N Primary outcome Serious AE Other AE Deaths
2019-06-26 Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radi PHASE3 60 Event-free Survival (EFS) 3 35 22

8 of these trials are still recruiting or active — see the condition's clinical trials page for the full landscape.

Which pages rest on the newest evidence

🔥 marks a page citing three or more papers from the last year — the pages worth re-reading if you have been away.

Page Newest citation In last year Total citations
intra-arterial-chemotherapy 2026-08-03 4 43
enucleation-and-high-risk-pathology 2026-07-03 4 41
classification-and-staging 2026-07-02 2 39
global-access-and-outcome-disparity 2026-07-01 3 43
systemic-chemotherapy 2026-07-01 3 41
molecular-pathogenesis-and-cell-of-origin 2026-05-01 3 41
intravitreal-and-intracameral-chemotherapy 2026-01-01 3 41
clinical-presentation-and-diagnosis 2025-12-01 2 45
red-flags-and-safety-concerns 2025-12-01 2 48
vision-outcomes-and-patient-experience 2025-12-01 2 43
clinical-trials-landscape 2025-10-02 1 38
genetic-testing-and-counselling 2025-09-02 0 41
rb1-genetics-and-heritability 2025-09-02 0 40
overview 2025-09-01 0 45
second-cancers-and-survivorship 2025-09-01 0 43
extraocular-metastatic-and-trilateral-disease 2025-07-04 0 43
epidemiology-and-global-burden 2025-07-02 0 40
guidelines 2025-05-01 0 44
focal-therapy-and-brachytherapy 2024-11-01 0 41

Recency is not quality: an old paper may be the definitive one, and a new paper may not replicate. Use this to find movement, not to rank evidence. See open questions for what remains unresolved, and the curation log for when these pages were last revised.