Master bibliography — asthma

Last curated: 2026-08-30. 401 unique PubMed-indexed papers cited across the 18 wiki pages and literature layer. Every PMID below was re-resolved through live PubMed E-utilities during the audit session. Papers are assigned to the first domain in which they appear; the cited by field preserves all cross-domain use.

Companion layers: guidelines/REGISTRY.md, statistics/STATISTICS.md, patient-voice/, and landmark notes in notes/.

Foundations, diagnosis and burden

• Malinovschi A, Kjellberg S, Romberg K, Wollmer P. [Pulmonary function testing in asthma]. Lakartidningen. 2025;122. PMID 40371566 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Meulmeester FL, Mailhot-Larouche S, Celis-Preciado C, et al. Inflammatory and clinical risk factors for asthma attacks (ORACLE2): a patient-level meta-analysis of control groups of 22 randomised trials. The Lancet. Respiratory medicine. 2025;13(6):505-516. DOI: 10.1016/S2213-2600(25)00037-2. PMID 40215991 — tags: [biomarkers, overview, phenotypes-endotypes-and-treatable-traits] — cited by: biomarkers.md, overview.md, phenotypes-endotypes-and-treatable-traits.md
• GBD 2021 Asthma and Allergic Diseases Collaborators. Global, regional, and national burden of asthma and atopic dermatitis, 1990-2021, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. The Lancet. Respiratory medicine. 2025;13(5):425-446. DOI: 10.1016/S2213-2600(25)00003-7. PMID 40147466 — tags: [epidemiology-and-global-burden, genetics-environment-and-prevention, overview] — cited by: epidemiology-and-global-burden.md, genetics-environment-and-prevention.md, overview.md
• Binney S, Flanders WD, Sircar K, Idubor O. Trends in US Pediatric Asthma Hospitalizations, by Race and Ethnicity, 2012-2020. Preventing chronic disease. 2024;21:E71. DOI: 10.5888/pcd21.240049. PMID 39298796 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Smith LB, O'Brien C, Kenney GM, Waidmann TA. Black-White Disparities in Asthma Hospitalizations and ED Visits Among Medicaid-Enrolled Children. Hospital pediatrics. 2024;14(6):490-498. DOI: 10.1542/hpeds.2023-007477. PMID 38752291 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Agache I, Canelo-Aybar C, Annesi-Maesano I, et al. The impact of outdoor pollution and extreme temperatures on asthma-related outcomes: A systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma. Allergy. 2024;79(7):1725-1760. DOI: 10.1111/all.16041. PMID 38311978 — tags: [epidemiology-and-global-burden, genetics-environment-and-prevention] — cited by: epidemiology-and-global-burden.md, genetics-environment-and-prevention.md
• Boparai S, Solomon GM. Interpretation of Spirometry, Peak Flow, and Provocation Testing for Asthma. Otolaryngologic clinics of North America. 2024;57(2):201-213. DOI: 10.1016/j.otc.2023.12.001. PMID 38151386 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Kilpatrick K, Ambrose CS, Lindsley AW, Oppenheimer J. At-home asthma mortality unchanged despite declining mortality in other settings: US death certificate data (2000-2019). Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2024;132(2):216-222. DOI: 10.1016/j.anai.2023.10.009. PMID 37848103 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Vyawahare AP, Gaidhane A, Wandile B. Asthma in Pregnancy: A Critical Review of Impact, Management, and Outcomes. Cureus. 2023;15(12):e50094. DOI: 10.7759/cureus.50094. PMID 38186538 — tags: [overview] — cited by: overview.md
• Merhej T, Zein JG. Epidemiology of Asthma: Prevalence and Burden of Disease. Advances in experimental medicine and biology. 2023;1426:3-23. DOI: 10.1007/978-3-031-32259-4_1. PMID 37464114 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Armeftis C, Gratziou C, Siafakas N, et al. An update on asthma diagnosis. The Journal of asthma : official journal of the Association for the Care of Asthma. 2023;60(12):2104-2110. DOI: 10.1080/02770903.2023.2228911. PMID 37358228 — tags: [diagnosis-and-objective-testing, epidemiology-and-global-burden] — cited by: diagnosis-and-objective-testing.md, epidemiology-and-global-burden.md
• Wang Z, Li Y, Gao Y, et al. Global, regional, and national burden of asthma and its attributable risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. Respiratory research. 2023;24(1):169. DOI: 10.1186/s12931-023-02475-6. PMID 37353829 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• D'Amato G, D'Amato M. Climate change, air pollution, pollen allergy and extreme atmospheric events. Current opinion in pediatrics. 2023;35(3):356-361. DOI: 10.1097/MOP.0000000000001237. PMID 36917187 — tags: [overview] — cited by: overview.md
• Simoneau T, Gaffin JM. Socioeconomic determinants of asthma health. Current opinion in pediatrics. 2023;35(3):337-343. DOI: 10.1097/MOP.0000000000001235. PMID 36861771 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• He LX, Liu CT. [Differential diagnosis of asthma and dysfunctional breathing and vocal cord dysfunction]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. 2022;45(9):936-941. DOI: 10.3760/cma.j.cn112147-20220314-00202. PMID 36097932 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Caimmi D, Demoly P. A review of allergen immunotherapy in asthma. Allergy and asthma proceedings. 2022;43(4):310-313. DOI: 10.2500/aap.2022.43.210113. PMID 35818140 — tags: [overview] — cited by: overview.md
• Escamilla-Gil JM, Fernandez-Nieto M, Acevedo N. Understanding the Cellular Sources of the Fractional Exhaled Nitric Oxide (FeNO) and Its Role as a Biomarker of Type 2 Inflammation in Asthma. BioMed research international. 2022;2022:5753524. DOI: 10.1155/2022/5753524. PMID 35547356 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Loewenthal L, Menzies-Gow A. FeNO in Asthma. Seminars in respiratory and critical care medicine. 2022;43(5):635-645. DOI: 10.1055/s-0042-1743290. PMID 35253144 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Garner O, Ramey JS, Hanania NA. Management of Life-Threatening Asthma: Severe Asthma Series. Chest. 2022;162(4):747-756. DOI: 10.1016/j.chest.2022.02.029. PMID 35218742 — tags: [exacerbations-and-acute-care, overview, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, overview.md, red-flags-and-safety-concerns.md
• Chawes B, Elenius V. Pulmonary function testing for the diagnosis of asthma in preschool children. Current opinion in allergy and clinical immunology. 2022;22(2):101-106. DOI: 10.1097/ACI.0000000000000815. PMID 35197431 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Yamada J, Lam Shin Cheung J, Gagne M, et al. Barriers and Enablers to Objective Testing for Asthma and COPD in Primary Care: A Systematic Review Using the Theoretical Domains Framework. Chest. 2022;161(4):888-905. DOI: 10.1016/j.chest.2021.10.030. PMID 34740591 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Pate CA, Zahran HS, Qin X, et al. Asthma Surveillance - United States, 2006-2018. Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002). 2021;70(5):1-32. DOI: 10.15585/mmwr.ss7005a1. PMID 34529643 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Menzies-Gow A, Corren J, Bourdin A, et al. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. The New England journal of medicine. 2021;384(19):1800-1809. DOI: 10.1056/NEJMoa2034975. PMID 33979488 — tags: [airway-immunobiology-and-remodeling, clinical-trials-landscape, overview, severe-asthma-and-biologics] — cited by: airway-immunobiology-and-remodeling.md, clinical-trials-landscape.md, overview.md, severe-asthma-and-biologics.md
• Gaillard EA, Kuehni CE, Turner S, et al. European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5-16 years. The European respiratory journal. 2021;58(5). DOI: 10.1183/13993003.04173-2020. PMID 33863747 — tags: [diagnosis-and-objective-testing, guidelines] — cited by: diagnosis-and-objective-testing.md, guidelines.md
• Ntontsi P, Photiades A, Zervas E, et al. Genetics and Epigenetics in Asthma. International journal of molecular sciences. 2021;22(5). DOI: 10.3390/ijms22052412. PMID 33673725 — tags: [genetics-environment-and-prevention, overview] — cited by: genetics-environment-and-prevention.md, overview.md
• Butler CA, Heaney LG. Fractional exhaled nitric oxide and asthma treatment adherence. Current opinion in allergy and clinical immunology. 2021;21(1):59-64. DOI: 10.1097/ACI.0000000000000704. PMID 33369570 — tags: [biomarkers, diagnosis-and-objective-testing, inhaler-technique-adherence-and-self-management] — cited by: biomarkers.md, diagnosis-and-objective-testing.md, inhaler-technique-adherence-and-self-management.md
• Asher MI, García-Marcos L, Pearce NE, Strachan DP. Trends in worldwide asthma prevalence. The European respiratory journal. 2020;56(6). DOI: 10.1183/13993003.02094-2020. PMID 32972987 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Cockcroft DW. Methacholine Challenge Testing in the Diagnosis of Asthma. Chest. 2020;158(2):433-434. DOI: 10.1016/j.chest.2020.04.034. PMID 32768054 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Rogliani P, Ritondo BL, Ora J, et al. SMART and as-needed therapies in mild-to-severe asthma: a network meta-analysis. The European respiratory journal. 2020;56(3). DOI: 10.1183/13993003.00625-2020. PMID 32430423 — tags: [mild-and-moderate-asthma, overview] — cited by: mild-and-moderate-asthma.md, overview.md
• Selvanathan J, Aaron SD, Sykes JR, et al. Performance Characteristics of Spirometry With Negative Bronchodilator Response and Methacholine Challenge Testing and Implications for Asthma Diagnosis. Chest. 2020;158(2):479-490. DOI: 10.1016/j.chest.2020.03.052. PMID 32298731 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Nwaru BI, Ekström M, Hasvold P, et al. Overuse of short-acting β2-agonists in asthma is associated with increased risk of exacerbation and mortality: a nationwide cohort study of the global SABINA programme. The European respiratory journal. 2020;55(4). DOI: 10.1183/13993003.01872-2019. PMID 31949111 — tags: [overview, red-flags-and-safety-concerns] — cited by: overview.md, red-flags-and-safety-concerns.md
• Yaghoubi M, Adibi A, Zafari Z, et al. Cost-effectiveness of implementing objective diagnostic verification of asthma in the United States. The Journal of allergy and clinical immunology. 2020;145(5):1367-1377.e4. DOI: 10.1016/j.jaci.2019.11.038. PMID 31837372 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Gans MD, Gavrilova T. Understanding the immunology of asthma: Pathophysiology, biomarkers, and treatments for asthma endotypes. Paediatric respiratory reviews. 2020;36:118-127. DOI: 10.1016/j.prrv.2019.08.002. PMID 31678040 — tags: [airway-immunobiology-and-remodeling, overview, phenotypes-endotypes-and-treatable-traits] — cited by: airway-immunobiology-and-remodeling.md, overview.md, phenotypes-endotypes-and-treatable-traits.md
• Pitchon RR, Alvim CG, Andrade CR, et al. Asthma mortality in children and adolescents of Brazil over a 20-year period. Jornal de pediatria. 2020;96(4):432-438. DOI: 10.1016/j.jped.2019.02.006. PMID 31009618 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Danvers L, Lo DKH, Gaillard EA. The role of objective tests to support a diagnosis of asthma in children. Paediatric respiratory reviews. 2020;33:52-57. DOI: 10.1016/j.prrv.2019.02.001. PMID 30954449 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Beasley R, Holliday M, Reddel HK, et al. Controlled Trial of Budesonide-Formoterol as Needed for Mild Asthma. The New England journal of medicine. 2019;380(21):2020-2030. DOI: 10.1056/NEJMoa1901963. PMID 31112386 — tags: [mild-and-moderate-asthma, overview] — cited by: mild-and-moderate-asthma.md, overview.md
• Mainardi AS, Castro M, Chupp G. Bronchial Thermoplasty. Clinics in chest medicine. 2019;40(1):193-207. DOI: 10.1016/j.ccm.2018.10.015. PMID 30691712 — tags: [overview] — cited by: overview.md
• Kuruvilla ME, Lee FE, Lee GB. Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease. Clinical reviews in allergy & immunology. 2019;56(2):219-233. DOI: 10.1007/s12016-018-8712-1. PMID 30206782 — tags: [overview, phenotypes-endotypes-and-treatable-traits] — cited by: overview.md, phenotypes-endotypes-and-treatable-traits.md
• Dean BW, Birnie EE, Whitmore GA, et al. Between-Visit Variability in FEV1 as a Diagnostic Test for Asthma in Adults. Annals of the American Thoracic Society. 2018;15(9):1039-1046. DOI: 10.1513/AnnalsATS.201803-211OC. PMID 29877740 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Castro M, Corren J, Pavord ID, et al. Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma. The New England journal of medicine. 2018;378(26):2486-2496. DOI: 10.1056/NEJMoa1804092. PMID 29782217 — tags: [airway-immunobiology-and-remodeling, clinical-trials-landscape, overview, severe-asthma-and-biologics] — cited by: airway-immunobiology-and-remodeling.md, clinical-trials-landscape.md, overview.md, severe-asthma-and-biologics.md
• O'Byrne PM, FitzGerald JM, Bateman ED, et al. Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma. The New England journal of medicine. 2018;378(20):1865-1876. DOI: 10.1056/NEJMoa1715274. PMID 29768149 — tags: [clinical-trials-landscape, mild-and-moderate-asthma, overview] — cited by: clinical-trials-landscape.md, mild-and-moderate-asthma.md, overview.md
• Bateman ED, Reddel HK, O'Byrne PM, et al. As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma. The New England journal of medicine. 2018;378(20):1877-1887. DOI: 10.1056/NEJMoa1715275. PMID 29768147 — tags: [mild-and-moderate-asthma, overview] — cited by: mild-and-moderate-asthma.md, overview.md
• Aaron SD, Boulet LP, Reddel HK, Gershon AS. Underdiagnosis and Overdiagnosis of Asthma. American journal of respiratory and critical care medicine. 2018;198(8):1012-1020. DOI: 10.1164/rccm.201804-0682CI. PMID 29756989 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Rothe T, Spagnolo P, Bridevaux PO, et al. Diagnosis and Management of Asthma - The Swiss Guidelines. Respiration; international review of thoracic diseases. 2018;95(5):364-380. DOI: 10.1159/000486797. PMID 29614508 — tags: [diagnosis-and-objective-testing, overview] — cited by: diagnosis-and-objective-testing.md, overview.md
• GBD 2015 Chronic Respiratory Disease Collaborators. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. Respiratory medicine. 2017;5(9):691-706. DOI: 10.1016/S2213-2600(17)30293-X. PMID 28822787 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Waljee AK, Rogers MA, Lin P, et al. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study. BMJ (Clinical research ed.). 2017;357:j1415. DOI: 10.1136/bmj.j1415. PMID 28404617 — tags: [overview] — cited by: overview.md
• Aaron SD, Vandemheen KL, FitzGerald JM, et al. Reevaluation of Diagnosis in Adults With Physician-Diagnosed Asthma. JAMA. 2017;317(3):269-279. DOI: 10.1001/jama.2016.19627. PMID 28114551 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Khreis H, Kelly C, Tate J, et al. Exposure to traffic-related air pollution and risk of development of childhood asthma: A systematic review and meta-analysis. Environment international. 2017;100:1-31. DOI: 10.1016/j.envint.2016.11.012. PMID 27881237 — tags: [epidemiology-and-global-burden, genetics-environment-and-prevention] — cited by: epidemiology-and-global-burden.md, genetics-environment-and-prevention.md
• Bleecker ER, FitzGerald JM, Chanez P, et al. Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trial. Lancet (London, England). 2016;388(10056):2115-2127. DOI: 10.1016/S0140-6736(16)31324-1. PMID 27609408 — tags: [airway-immunobiology-and-remodeling, overview, phenotypes-endotypes-and-treatable-traits, severe-asthma-and-biologics] — cited by: airway-immunobiology-and-remodeling.md, overview.md, phenotypes-endotypes-and-treatable-traits.md, severe-asthma-and-biologics.md
• Ober C. Asthma Genetics in the Post-GWAS Era. Annals of the American Thoracic Society. 2016;13 Suppl 1(Suppl 1):S85-90. DOI: 10.1513/AnnalsATS.201507-459MG. PMID 27027959 — tags: [genetics-environment-and-prevention, overview] — cited by: genetics-environment-and-prevention.md, overview.md
• Ehteshami-Afshar S, FitzGerald JM, Doyle-Waters MM, Sadatsafavi M. The global economic burden of asthma and chronic obstructive pulmonary disease. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2016;20(1):11-23. DOI: 10.5588/ijtld.15.0472. PMID 26688525 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Jolly AT, Klees JE, Pacheco KA, et al. Work-Related Asthma. Journal of occupational and environmental medicine. 2015;57(10):e121-9. DOI: 10.1097/JOM.0000000000000572. PMID 26461873 — tags: [diagnosis-and-objective-testing, genetics-environment-and-prevention] — cited by: diagnosis-and-objective-testing.md, genetics-environment-and-prevention.md
• Sears MR. Predicting asthma outcomes. The Journal of allergy and clinical immunology. 2015;136(4):829-36; quiz 837. DOI: 10.1016/j.jaci.2015.04.048. PMID 26449797 — tags: [overview] — cited by: overview.md
• Brigham EP, West NE. Diagnosis of asthma: diagnostic testing. International forum of allergy & rhinology. 2015;5 Suppl 1:S27-30. DOI: 10.1002/alr.21597. PMID 26335833 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Rhee CK. Phenotype of asthma-chronic obstructive pulmonary disease overlap syndrome. The Korean journal of internal medicine. 2015;30(4):443-9. DOI: 10.3904/kjim.2015.30.4.443. PMID 26161009 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Loftus PA, Wise SK. Epidemiology and economic burden of asthma. International forum of allergy & rhinology. 2015;5 Suppl 1:S7-10. DOI: 10.1002/alr.21547. PMID 26010063 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Fahy JV. Type 2 inflammation in asthma--present in most, absent in many. Nature reviews. Immunology. 2015;15(1):57-65. DOI: 10.1038/nri3786. PMID 25534623 — tags: [airway-immunobiology-and-remodeling, biomarkers, overview] — cited by: airway-immunobiology-and-remodeling.md, biomarkers.md, overview.md
• Wu TJ, Wu CF, Lee YL, et al. Asthma incidence, remission, relapse and persistence: a population-based study in southern Taiwan. Respiratory research. 2014;15(1):135. DOI: 10.1186/s12931-014-0135-9. PMID 25387792 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Asher I, Pearce N. Global burden of asthma among children. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2014;18(11):1269-78. DOI: 10.5588/ijtld.14.0170. PMID 25299857 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Ortega HG, Liu MC, Pavord ID, et al. Mepolizumab treatment in patients with severe eosinophilic asthma. The New England journal of medicine. 2014;371(13):1198-207. DOI: 10.1056/NEJMoa1403290. PMID 25199059 — tags: [overview, severe-asthma-and-biologics] — cited by: overview.md, severe-asthma-and-biologics.md
• Mallol J, Crane J, von Mutius E, et al. The International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three: a global synthesis. Allergologia et immunopathologia. 2013;41(2):73-85. DOI: 10.1016/j.aller.2012.03.001. PMID 22771150 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Pavord ID, Korn S, Howarth P, et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet (London, England). 2012;380(9842):651-9. DOI: 10.1016/S0140-6736(12)60988-X. PMID 22901886 — tags: [airway-immunobiology-and-remodeling, clinical-trials-landscape, overview, phenotypes-endotypes-and-treatable-traits, severe-asthma-and-biologics] — cited by: airway-immunobiology-and-remodeling.md, clinical-trials-landscape.md, overview.md, phenotypes-endotypes-and-treatable-traits.md, severe-asthma-and-biologics.md
• Urso DL, Daniele V, Formaro L, Urso G. [Diagnosis and treatment of asthma]. Recenti progressi in medicina. 2012;103(7-8):284-7. DOI: 10.1701/1127.12432. PMID 22825384 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Tepper RS, Wise RS, Covar R, et al. Asthma outcomes: pulmonary physiology. The Journal of allergy and clinical immunology. 2012;129(3 Suppl):S65-87. DOI: 10.1016/j.jaci.2011.12.986. PMID 22386510 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Dweik RA, Boggs PB, Erzurum SC, et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. American journal of respiratory and critical care medicine. 2011;184(5):602-15. DOI: 10.1164/rccm.9120-11ST. PMID 21885636 — tags: [biomarkers, diagnosis-and-objective-testing, guidelines] — cited by: biomarkers.md, diagnosis-and-objective-testing.md, guidelines.md
• Bahadori K, Doyle-Waters MM, Marra C, et al. Economic burden of asthma: a systematic review. BMC pulmonary medicine. 2009;9:24. DOI: 10.1186/1471-2466-9-24. PMID 19454036 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Lai CK, Beasley R, Crane J, et al. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009;64(6):476-83. DOI: 10.1136/thx.2008.106609. PMID 19237391 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Aaron SD, Vandemheen KL, Boulet LP, et al. Overdiagnosis of asthma in obese and nonobese adults. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2008;179(11):1121-31. DOI: 10.1503/cmaj.081332. PMID 19015563 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Pérez-Padilla R, Torre-Bouscoulet L. Understanding and preventing asthma-related deaths. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2008;34(8):545. DOI: 10.1590/s1806-37132008000800001. PMID 18797736 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Asher MI, Montefort S, Björkstén B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet (London, England). 2006;368(9537):733-43. DOI: 10.1016/S0140-6736(06)69283-0. PMID 16935684 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Eagan TM, Brøgger JC, Eide GE, Bakke PS. The incidence of adult asthma: a review. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2005;9(6):603-12. PMID 15971386 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Gold DR, Wright R. Population disparities in asthma. Annual review of public health. 2005;26:89-113. DOI: 10.1146/annurev.publhealth.26.021304.144528. PMID 15760282 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md
• Humbert M, Beasley R, Ayres J, et al. Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy. 2005;60(3):309-16. DOI: 10.1111/j.1398-9995.2004.00772.x. PMID 15679715 — tags: [airway-immunobiology-and-remodeling, overview, phenotypes-endotypes-and-treatable-traits, severe-asthma-and-biologics] — cited by: airway-immunobiology-and-remodeling.md, overview.md, phenotypes-endotypes-and-treatable-traits.md, severe-asthma-and-biologics.md
• Tarlo SM. Laboratory challenge testing for occupational asthma. The Journal of allergy and clinical immunology. 2003;111(4):692-4. DOI: 10.1067/mai.2003.1374. PMID 12704344 — tags: [diagnosis-and-objective-testing] — cited by: diagnosis-and-objective-testing.md
• Chen Y, Stewart P, Johansen H, et al. Sex difference in hospitalization due to asthma in relation to age. Journal of clinical epidemiology. 2003;56(2):180-7. DOI: 10.1016/s0895-4356(02)00593-0. PMID 12654413 — tags: [epidemiology-and-global-burden] — cited by: epidemiology-and-global-burden.md

Mechanisms, genetics and phenotypes

• Koppelman GH, Pino-Yanes M, Melén E, et al. Genetic and environmental risk factors for asthma: towards prevention. The Lancet. Respiratory medicine. 2025;13(11):1011-1025. DOI: 10.1016/S2213-2600(25)00256-5. PMID 41038211 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Shackleford A, Heaney LG, Redmond C, et al. Clinical remission attainment, definitions, and correlates among patients with severe asthma treated with biologics: a systematic review and meta-analysis. The Lancet. Respiratory medicine. 2025;13(1):23-34. DOI: 10.1016/S2213-2600(24)00293-5. PMID 39549709 — tags: [clinical-trials-landscape, phenotypes-endotypes-and-treatable-traits, severe-asthma-and-biologics] — cited by: clinical-trials-landscape.md, phenotypes-endotypes-and-treatable-traits.md, severe-asthma-and-biologics.md
• Lee S, Tian D, He R, et al. Ambient air pollution exposure and adult asthma incidence: a systematic review and meta-analysis. The Lancet. Planetary health. 2024;8(12):e1065-e1078. DOI: 10.1016/S2542-5196(24)00279-1. PMID 39674196 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Kermani NZ, Li CX, Versi A, et al. Endotypes of severe neutrophilic and eosinophilic asthma from multi-omics integration of U-BIOPRED sputum samples. Clinical and translational medicine. 2024;14(7):e1771. DOI: 10.1002/ctm2.1771. PMID 39073027 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Agache I, Ricci-Cabello I, Canelo-Aybar C, et al. The impact of exposure to tobacco smoke and e-cigarettes on asthma-related outcomes: Systematic review informing the EAACI guidelines on environmental science for allergic diseases and asthma. Allergy. 2024;79(9):2346-2365. DOI: 10.1111/all.16151. PMID 38783343 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Porsbjerg CM, Townend J, Bergeron C, et al. Association between pre-biologic T2-biomarker combinations and response to biologics in patients with severe asthma. Frontiers in immunology. 2024;15:1361891. DOI: 10.3389/fimmu.2024.1361891. PMID 38711495 — tags: [biomarkers] — cited by: biomarkers.md
• Bacharier LB, Pavord ID, Maspero JF, et al. Blood eosinophils and fractional exhaled nitric oxide are prognostic and predictive biomarkers in childhood asthma. The Journal of allergy and clinical immunology. 2024;154(1):101-110. DOI: 10.1016/j.jaci.2023.09.044. PMID 38272375 — tags: [biomarkers] — cited by: biomarkers.md
• Balmes JR, Holm SM. Increasing wildfire smoke from the climate crisis: Impacts on asthma and allergies. The Journal of allergy and clinical immunology. 2023;152(5):1081-1083. DOI: 10.1016/j.jaci.2023.09.008. PMID 37739070 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Curren B, Ahmed T, Howard DR, et al. IL-33-induced neutrophilic inflammation and NETosis underlie rhinovirus-triggered exacerbations of asthma. Mucosal immunology. 2023;16(5):671-684. DOI: 10.1016/j.mucimm.2023.07.002. PMID 37506849 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Korevaar DA, Damen JA, Heus P, et al. Effectiveness of FeNO-guided treatment in adult asthma patients: A systematic review and meta-analysis. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2023;53(8):798-808. DOI: 10.1111/cea.14359. PMID 37293870 — tags: [biomarkers] — cited by: biomarkers.md
• Rosas-Salazar C, Chirkova T, Gebretsadik T, et al. Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study. Lancet (London, England). 2023;401(10389):1669-1680. DOI: 10.1016/S0140-6736(23)00811-5. PMID 37086744 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Baatjies R, Chamba P, Jeebhay MF. Wood dust and asthma. Current opinion in allergy and clinical immunology. 2023;23(2):76-84. DOI: 10.1097/ACI.0000000000000882. PMID 36821481 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Gvalani A, Athavale A, Gupta D. Biomarkers in severe asthma: Identifying the treatable trait. Lung India : official organ of Indian Chest Society. 2023;40(1):59-67. DOI: 10.4103/lungindia.lungindia_271_22. PMID 36695260 — tags: [biomarkers] — cited by: biomarkers.md
• Donovan GM, Wang KCW, Elliot JG, et al. Quantifying airway remodelling for research or clinical purposes: How should we normalize for airway size? Respirology (Carlton, Vic.). 2023;28(3):223-225. DOI: 10.1111/resp.14454. PMID 36691759 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Gauvreau GM, Bergeron C, Boulet LP, et al. Sounding the alarmins-The role of alarmin cytokines in asthma. Allergy. 2023;78(2):402-417. DOI: 10.1111/all.15609. PMID 36463491 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Tsuo K, Zhou W, Wang Y, et al. Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity. Cell genomics. 2022;2(12):100212. DOI: 10.1016/j.xgen.2022.100212. PMID 36778051 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Niessen NM, Fricker M, McDonald VM, Gibson PG. T2-low: what do we know?: Past, present, and future of biologic therapies in noneosinophilic asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2022;129(2):150-159. DOI: 10.1016/j.anai.2022.04.020. PMID 35487388 — tags: [biomarkers] — cited by: biomarkers.md
• Makrinioti H, Hasegawa K, Lakoumentas J, et al. The role of respiratory syncytial virus- and rhinovirus-induced bronchiolitis in recurrent wheeze and asthma-A systematic review and meta-analysis. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 2022;33(3):e13741. DOI: 10.1111/pai.13741. PMID 35338734 — tags: [asthma-in-children, genetics-environment-and-prevention] — cited by: asthma-in-children.md, genetics-environment-and-prevention.md
• Nuzzi G, Di Cicco M, Trambusti I, et al. Primary Prevention of Pediatric Asthma through Nutritional Interventions. Nutrients. 2022;14(4). DOI: 10.3390/nu14040754. PMID 35215404 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Tang M, Elicker BM, Henry T, et al. Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time. American journal of respiratory and critical care medicine. 2022;205(9):1036-1045. DOI: 10.1164/rccm.202110-2265OC. PMID 35104436 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Corren J, Pham TH, Garcia Gil E, et al. Baseline type 2 biomarker levels and response to tezepelumab in severe asthma. Allergy. 2022;77(6):1786-1796. DOI: 10.1111/all.15197. PMID 34913186 — tags: [biomarkers, severe-asthma-and-biologics] — cited by: biomarkers.md, severe-asthma-and-biologics.md
• Watanabe H, Shirai T, Hirai K, et al. Blood eosinophil count and FeNO to predict benralizumab effectiveness in real-life severe asthma patients. The Journal of asthma : official journal of the Association for the Care of Asthma. 2022;59(9):1796-1804. DOI: 10.1080/02770903.2021.1963769. PMID 34348060 — tags: [biomarkers] — cited by: biomarkers.md
• Diver S, Khalfaoui L, Emson C, et al. Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial. The Lancet. Respiratory medicine. 2021;9(11):1299-1312. DOI: 10.1016/S2213-2600(21)00226-5. PMID 34256031 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Kelsen SG, Agache IO, Soong W, et al. Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial. The Journal of allergy and clinical immunology. 2021;148(3):790-798. DOI: 10.1016/j.jaci.2021.03.044. PMID 33872652 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Lee Y, Quoc QL, Park HS. Biomarkers for Severe Asthma: Lessons From Longitudinal Cohort Studies. Allergy, asthma & immunology research. 2021;13(3):375-389. DOI: 10.4168/aair.2021.13.3.375. PMID 33733634 — tags: [biomarkers] — cited by: biomarkers.md
• Moss RB. Diagnosing allergic bronchopulmonary aspergillosis/mycosis: Return to lost horizons. The Journal of allergy and clinical immunology. 2021;147(4):1212-1214. DOI: 10.1016/j.jaci.2021.01.017. PMID 33529689 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Stevens WW, Jerschow E, Baptist AP, et al. The role of aspirin desensitization followed by oral aspirin therapy in managing patients with aspirin-exacerbated respiratory disease: A Work Group Report from the Rhinitis, Rhinosinusitis and Ocular Allergy Committee of the American Academy of Allergy, Asthma & Immunology. The Journal of allergy and clinical immunology. 2021;147(3):827-844. DOI: 10.1016/j.jaci.2020.10.043. PMID 33307116 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Hiles SA, Gibson PG, Agusti A, McDonald VM. Treatable Traits That Predict Health Status and Treatment Response in Airway Disease. The journal of allergy and clinical immunology. In practice. 2021;9(3):1255-1264.e2. DOI: 10.1016/j.jaip.2020.09.046. PMID 33039647 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Kermani NZ, Pavlidis S, Xie J, et al. Instability of sputum molecular phenotypes in U-BIOPRED severe asthma. The European respiratory journal. 2021;57(2). DOI: 10.1183/13993003.01836-2020. PMID 33008937 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Jia X, Li S, Xu T, et al. Diagnostic accuracy of periostin in predicting asthma: a systematic review and Meta-analysis. The Journal of asthma : official journal of the Association for the Care of Asthma. 2021;58(3):307-315. DOI: 10.1080/02770903.2019.1684518. PMID 31738608 — tags: [biomarkers] — cited by: biomarkers.md
• Hudey SN, Ledford DK, Cardet JC. Mechanisms of non-type 2 asthma. Current opinion in immunology. 2020;66:123-128. DOI: 10.1016/j.coi.2020.10.002. PMID 33160187 — tags: [airway-immunobiology-and-remodeling, phenotypes-endotypes-and-treatable-traits] — cited by: airway-immunobiology-and-remodeling.md, phenotypes-endotypes-and-treatable-traits.md
• Yang L, Zhao Q, Wang S. The role of serum periostin in the diagnosis of asthma: A meta-analysis. Allergy and asthma proceedings. 2020;41(4):240-247. DOI: 10.2500/aap.2020.41.200038. PMID 32605695 — tags: [biomarkers] — cited by: biomarkers.md
• Wang X, Tan X, Li Q. Effectiveness of fractional exhaled nitric oxide for asthma management in children: A systematic review and meta-analysis. Pediatric pulmonology. 2020;55(8):1936-1945. DOI: 10.1002/ppul.24898. PMID 32525611 — tags: [biomarkers] — cited by: biomarkers.md
• Banno A, Reddy AT, Lakshmi SP, Reddy RC. Bidirectional interaction of airway epithelial remodeling and inflammation in asthma. Clinical science (London, England : 1979). 2020;134(9):1063-1079. DOI: 10.1042/CS20191309. PMID 32369100 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Malinovschi A. Limited use of biomarker-guided therapy in mild asthma. The Lancet. Respiratory medicine. 2020;8(7):648-649. DOI: 10.1016/S2213-2600(20)30074-6. PMID 32171066 — tags: [biomarkers] — cited by: biomarkers.md
• Hufnagl K, Pali-Schöll I, Roth-Walter F, Jensen-Jarolim E. Dysbiosis of the gut and lung microbiome has a role in asthma. Seminars in immunopathology. 2020;42(1):75-93. DOI: 10.1007/s00281-019-00775-y. PMID 32072252 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Toki S, Goleniewska K, Zhang J, et al. TSLP and IL-33 reciprocally promote each other's lung protein expression and ILC2 receptor expression to enhance innate type-2 airway inflammation. Allergy. 2020;75(7):1606-1617. DOI: 10.1111/all.14196. PMID 31975538 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Zhang C, Jiang Z, Shao C. Clinical characteristics of allergic bronchopulmonary aspergillosis. The clinical respiratory journal. 2020;14(5):440-446. DOI: 10.1111/crj.13147. PMID 31901186 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Menzies-Gow A, Bafadhel M, Busse WW, et al. An expert consensus framework for asthma remission as a treatment goal. The Journal of allergy and clinical immunology. 2020;145(3):757-765. DOI: 10.1016/j.jaci.2019.12.006. PMID 31866436 — tags: [phenotypes-endotypes-and-treatable-traits, severe-asthma-and-biologics] — cited by: phenotypes-endotypes-and-treatable-traits.md, severe-asthma-and-biologics.md
• McDonald VM, Clark VL, Cordova-Rivera L, et al. Targeting treatable traits in severe asthma: a randomised controlled trial. The European respiratory journal. 2020;55(3). DOI: 10.1183/13993003.01509-2019. PMID 31806719 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Nelson RK, Bush A, Stokes J, et al. Eosinophilic Asthma. The journal of allergy and clinical immunology. In practice. 2020;8(2):465-473. DOI: 10.1016/j.jaip.2019.11.024. PMID 31786254 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Gauvreau GM, White L, Davis BE. Anti-alarmin approaches entering clinical trials. Current opinion in pulmonary medicine. 2020;26(1):69-76. DOI: 10.1097/MCP.0000000000000615. PMID 31408015 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Sze E, Bhalla A, Nair P. Mechanisms and therapeutic strategies for non-T2 asthma. Allergy. 2020;75(2):311-325. DOI: 10.1111/all.13985. PMID 31309578 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Narendra D, Blixt J, Hanania NA. Immunological biomarkers in severe asthma. Seminars in immunology. 2019;46:101332. DOI: 10.1016/j.smim.2019.101332. PMID 31735516 — tags: [biomarkers] — cited by: biomarkers.md
• Padem N, Saltoun C. Classification of asthma. Allergy and asthma proceedings. 2019;40(6):385-388. DOI: 10.2500/aap.2019.40.4253. PMID 31690376 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Watchorn D, Madden A, O'Shea D, et al. Weight Loss in Individuals with Obesity and Asthma. Annals of the American Thoracic Society. 2019;16(7):933-934. DOI: 10.1513/AnnalsATS.201902-151LE. PMID 30969796 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Ahovuo-Saloranta A, Csonka P, Lehtimäki L. Basic characteristics and clinical value of FeNO in smoking asthmatics-a systematic review. Journal of breath research. 2019;13(3):034003. DOI: 10.1088/1752-7163/ab0ece. PMID 30861509 — tags: [biomarkers] — cited by: biomarkers.md
• Seys SF, Lokwani R, Simpson JL, Bullens DMA. New insights in neutrophilic asthma. Current opinion in pulmonary medicine. 2019;25(1):113-120. DOI: 10.1097/MCP.0000000000000543. PMID 30422895 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Simpson AJ, Hekking PP, Shaw DE, et al. Treatable traits in the European U-BIOPRED adult asthma cohorts. Allergy. 2019;74(2):406-411. DOI: 10.1111/all.13629. PMID 30307629 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Kowalski ML, Agache I, Bavbek S, et al. Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)-a EAACI position paper. Allergy. 2019;74(1):28-39. DOI: 10.1111/all.13599. PMID 30216468 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Tliba O, Panettieri RA. Paucigranulocytic asthma: Uncoupling of airway obstruction from inflammation. The Journal of allergy and clinical immunology. 2019;143(4):1287-1294. DOI: 10.1016/j.jaci.2018.06.008. PMID 29928921 — tags: [airway-immunobiology-and-remodeling, phenotypes-endotypes-and-treatable-traits] — cited by: airway-immunobiology-and-remodeling.md, phenotypes-endotypes-and-treatable-traits.md
• Petsky HL, Cates CJ, Kew KM, Chang AB. Tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils): a systematic review and meta-analysis. Thorax. 2018;73(12):1110-1119. DOI: 10.1136/thoraxjnl-2018-211540. PMID 29858277 — tags: [biomarkers] — cited by: biomarkers.md
• Garden FL, Toelle BG, Mihrshahi S, et al. Cohort profile: The Childhood Asthma Prevention Study (CAPS). International journal of epidemiology. 2018;47(6):1736-1736k. DOI: 10.1093/ije/dyy078. PMID 29800224 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Curtis EM, Moon RJ, Harvey NC, Cooper C. Maternal vitamin D supplementation during pregnancy. British medical bulletin. 2018;126(1):57-77. DOI: 10.1093/bmb/ldy010. PMID 29684104 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Peters U, Dixon AE, Forno E. Obesity and asthma. The Journal of allergy and clinical immunology. 2018;141(4):1169-1179. DOI: 10.1016/j.jaci.2018.02.004. PMID 29627041 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Dunican EM, Elicker BM, Gierada DS, et al. Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation. 2018;128(3):997-1009. DOI: 10.1172/JCI95693. PMID 29400693 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Fingleton J, Hardy J, Beasley R. Treatable traits of chronic airways disease. Current opinion in pulmonary medicine. 2018;24(1):24-31. DOI: 10.1097/MCP.0000000000000445. PMID 29049049 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
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• Ober C, Sperling AI, von Mutius E, Vercelli D. Immune development and environment: lessons from Amish and Hutterite children. Current opinion in immunology. 2017;48:51-60. DOI: 10.1016/j.coi.2017.08.003. PMID 28843541 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Das S, Miller M, Broide DH. Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases. Advances in immunology. 2017;135:1-52. DOI: 10.1016/bs.ai.2017.06.001. PMID 28826527 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Fehrenbach H, Wagner C, Wegmann M. Airway remodeling in asthma: what really matters. Cell and tissue research. 2017;367(3):551-569. DOI: 10.1007/s00441-016-2566-8. PMID 28190087 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Mitchell PD, O'Byrne PM. Epithelial-Derived Cytokines in Asthma. Chest. 2017;151(6):1338-1344. DOI: 10.1016/j.chest.2016.10.042. PMID 27818325 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Lefaudeux D, De Meulder B, Loza MJ, et al. U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics. The Journal of allergy and clinical immunology. 2017;139(6):1797-1807. DOI: 10.1016/j.jaci.2016.08.048. PMID 27773852 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Karrasch S, Linde K, Rücker G, et al. Accuracy of FENO for diagnosing asthma: a systematic review. Thorax. 2017;72(2):109-116. DOI: 10.1136/thoraxjnl-2016-208704. PMID 27388487 — tags: [biomarkers] — cited by: biomarkers.md
• Kennedy JL, Stoner AN, Borish L. Aspirin-exacerbated respiratory disease: Prevalence, diagnosis, treatment, and considerations for the future. American journal of rhinology & allergy. 2016;30(6):407-413. DOI: 10.2500/ajra.2016.30.4370. PMID 28124651 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Smits HH, Hiemstra PS, Prazeres da Costa C, et al. Microbes and asthma: Opportunities for intervention. The Journal of allergy and clinical immunology. 2016;137(3):690-7. DOI: 10.1016/j.jaci.2016.01.004. PMID 26947981 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
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• Matsumoto H. Serum periostin: a novel biomarker for asthma management. Allergology international : official journal of the Japanese Society of Allergology. 2014;63(2):153-60. DOI: 10.2332/allergolint.13-RAI-0678. PMID 24759559 — tags: [biomarkers] — cited by: biomarkers.md
• Tarlo SM, Lemiere C. Occupational asthma. The New England journal of medicine. 2014;370(7):640-9. DOI: 10.1056/NEJMra1301758. PMID 24521110 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Peters MC, Mekonnen ZK, Yuan S, et al. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. The Journal of allergy and clinical immunology. 2014;133(2):388-94. DOI: 10.1016/j.jaci.2013.07.036. PMID 24075231 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Hirota N, Martin JG. Mechanisms of airway remodeling. Chest. 2013;144(3):1026-1032. DOI: 10.1378/chest.12-3073. PMID 24008953 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Agarwal R, Chakrabarti A, Shah A, et al. Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2013;43(8):850-73. DOI: 10.1111/cea.12141. PMID 23889240 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• Tinuoye O, Pell JP, Mackay DF. Meta-analysis of the association between secondhand smoke exposure and physician-diagnosed childhood asthma. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2013;15(9):1475-83. DOI: 10.1093/ntr/ntt033. PMID 23539174 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Levin AM, Mathias RA, Huang L, et al. A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. The Journal of allergy and clinical immunology. 2013;131(4):1176-84. DOI: 10.1016/j.jaci.2012.10.002. PMID 23146381 — tags: [biomarkers] — cited by: biomarkers.md
• Jartti T, Wendelin-Saarenhovi M, Heinonen I, et al. Childhood asthma management guided by repeated FeNO measurements: a meta-analysis. Paediatric respiratory reviews. 2012;13(3):178-83. DOI: 10.1016/j.prrv.2011.11.002. PMID 22726875 — tags: [biomarkers] — cited by: biomarkers.md
• Petsky HL, Cates CJ, Lasserson TJ, et al. A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils). Thorax. 2012;67(3):199-208. DOI: 10.1136/thx.2010.135574. PMID 20937641 — tags: [biomarkers] — cited by: biomarkers.md
• Jartti T, Korppi M. Rhinovirus-induced bronchiolitis and asthma development. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 2011;22(4):350-5. DOI: 10.1111/j.1399-3038.2011.01170.x. PMID 21535176 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Choy DF, Modrek B, Abbas AR, et al. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. Journal of immunology (Baltimore, Md. : 1950). 2011;186(3):1861-9. DOI: 10.4049/jimmunol.1002568. PMID 21187436 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Venge P. The eosinophil and airway remodelling in asthma. The clinical respiratory journal. 2010;4 Suppl 1:15-9. DOI: 10.1111/j.1752-699X.2010.00192.x. PMID 20500605 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Moore WC, Meyers DA, Wenzel SE, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. American journal of respiratory and critical care medicine. 2010;181(4):315-23. DOI: 10.1164/rccm.200906-0896OC. PMID 19892860 — tags: [phenotypes-endotypes-and-treatable-traits] — cited by: phenotypes-endotypes-and-treatable-traits.md
• London SJ, Romieu I. Gene by environment interaction in asthma. Annual review of public health. 2009;30:55-80. DOI: 10.1146/annurev.publhealth.031308.100151. PMID 18980546 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Holgate ST. Pathogenesis of asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2008;38(6):872-97. DOI: 10.1111/j.1365-2222.2008.02971.x. PMID 18498538 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Holgate ST. Epithelium dysfunction in asthma. The Journal of allergy and clinical immunology. 2007;120(6):1233-44; quiz 1245-6. DOI: 10.1016/j.jaci.2007.10.025. PMID 18073119 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Woodruff PG, Boushey HA, Dolganov GM, et al. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proceedings of the National Academy of Sciences of the United States of America. 2007;104(40):15858-63. DOI: 10.1073/pnas.0707413104. PMID 17898169 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Black JL. Asthma--more muscle cells or more muscular cells? American journal of respiratory and critical care medicine. 2004;169(9):980-1. DOI: 10.1164/rccm.2402024. PMID 15107302 — tags: [airway-immunobiology-and-remodeling] — cited by: airway-immunobiology-and-remodeling.md
• Abramson MJ, Puy RM, Weiner JM. Allergen immunotherapy for asthma. The Cochrane database of systematic reviews. 2003;(4):CD001186. DOI: 10.1002/14651858.CD001186. PMID 14583928 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md
• Torén K, Järvholm B, Brisman J, et al. Adult-onset asthma and occupational exposures. Scandinavian journal of work, environment & health. 1999;25(5):430-5. DOI: 10.5271/sjweh.456. PMID 10569463 — tags: [genetics-environment-and-prevention] — cited by: genetics-environment-and-prevention.md

Treatment and acute care

• Abu-Sultaneh S, Miller AG, Basnet S, et al. Intravenous Bronchodilators in Pediatric Critical Asthma: A Systematic Review and Network Meta-Analysis. Pediatric pulmonology. 2025;60(7):e71192. DOI: 10.1002/ppul.71192. PMID 40637351 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Tsao CL, Chan SY, Lee MH, et al. Adverse Outcomes Associated With Short-Acting Beta-Agonist Overuse in Asthma: A Systematic Review and Meta-Analysis. Allergy. 2025;80(6):1629-1646. DOI: 10.1111/all.16538. PMID 40491263 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• LaForce C, Albers F, Danilewicz A, et al. As-Needed Albuterol-Budesonide in Mild Asthma. The New England journal of medicine. 2025;393(2):113-124. DOI: 10.1056/NEJMoa2504544. PMID 40388330 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• van de Hei SJ, van den Berg LN, Poot CC, et al. Long-Term Effectiveness of a Digital Inhaler on Medication Adherence and Clinical Outcomes in Adult Asthma Patients in Primary Care: The Cluster Randomized Controlled ACCEPTANCE Trial. The journal of allergy and clinical immunology. In practice. 2025;13(7):1693-1704. DOI: 10.1016/j.jaip.2025.03.013. PMID 40118212 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Mosnaim G, Carrasquel M, Ewing T, et al. Remote monitoring in asthma: a systematic review. European respiratory review : an official journal of the European Respiratory Society. 2025;34(175). DOI: 10.1183/16000617.0143-2024. PMID 40107660 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Marko M, Pawliczak R. Inhalation technique-related errors after education among asthma and COPD patients using different types of inhalers - systematic review and meta-analysis. NPJ primary care respiratory medicine. 2025;35(1):15. DOI: 10.1038/s41533-025-00422-0. PMID 40102397 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Homer-Bouthiette C, Wilson KC. Noninvasive Ventilation in Acute Asthma Exacerbations: A Systematic Review. Annals of the American Thoracic Society. 2025;22(5):776-784. DOI: 10.1513/AnnalsATS.202407-799OC. PMID 39642363 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Rayner DG, Ferri DM, Guyatt GH, et al. Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis. JAMA. 2025;333(2):143-152. DOI: 10.1001/jama.2024.22700. PMID 39465893 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Watson AJR, Roe T, Arscott O, et al. Characteristics, Management, and Outcomes of Acute Life-Threatening Asthma in Adult Intensive Care. Clinics and practice. 2024;14(5):1886-1897. DOI: 10.3390/clinpract14050149. PMID 39311299 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Kumar J, Kumar P, Goyal JP, et al. Role of nebulised magnesium sulfate in treating acute asthma in children: a systematic review and meta-analysis. BMJ paediatrics open. 2024;8(1). DOI: 10.1136/bmjpo-2024-002638. PMID 38782483 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Kandola A, Edwards K, Straatman J, et al. Digital Self-Management Platform for Adult Asthma: Randomized Attention-Placebo Controlled Trial. Journal of medical Internet research. 2024;26:e50855. DOI: 10.2196/50855. PMID 38684084 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Kyriakopoulos C, Gogali A, Markozannes G, Kostikas K. Biologic agents licensed for severe asthma: a systematic review and meta-analysis of randomised controlled trials. European respiratory review : an official journal of the European Respiratory Society. 2024;33(172). DOI: 10.1183/16000617.0238-2023. PMID 38657997 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Politis J, Chung LP, Igwe E, et al. Oral corticosteroid stewardship: key insights from the Australasian Severe Asthma Registry. Internal medicine journal. 2024;54(7):1136-1145. DOI: 10.1111/imj.16392. PMID 38622806 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Varghese D, Ferris K, Lee B, et al. Outdoor air pollution and near-fatal/fatal asthma attacks in children: A systematic review. Pediatric pulmonology. 2024;59(5):1196-1206. DOI: 10.1002/ppul.26932. PMID 38477643 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Ambrożej D, Adamiec A, Forno E, et al. Intravenous magnesium sulfate for asthma exacerbations in children: Systematic review with meta-analysis. Paediatric respiratory reviews. 2024;52:23-30. DOI: 10.1016/j.prrv.2024.01.003. PMID 38395640 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Gayen S, Dachert S, Lashari BH, et al. Critical Care Management of Severe Asthma Exacerbations. Journal of clinical medicine. 2024;13(3). DOI: 10.3390/jcm13030859. PMID 38337552 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Phinyo P, Krikeerati T, Vichara-Anont I, Thongngarm T. Efficacy and Safety of Biologics for Oral Corticosteroid-Dependent Asthma: A Systematic Review and Network Meta-Analysis. The journal of allergy and clinical immunology. In practice. 2024;12(2):409-420. DOI: 10.1016/j.jaip.2023.11.007. PMID 37972921 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Mayoral K, Lizano-Barrantes C, Zamora V, et al. Montelukast in paediatric asthma and allergic rhinitis: a systematic review and meta-analysis. European respiratory review : an official journal of the European Respiratory Society. 2023;32(170). DOI: 10.1183/16000617.0124-2023. PMID 37852659 — tags: [asthma-in-children, mild-and-moderate-asthma] — cited by: asthma-in-children.md, mild-and-moderate-asthma.md
• Loh ZC, Hussain R, Ong SC, et al. Over-the-counter use of short-acting beta-2 agonists: a systematic review. Journal of pharmaceutical policy and practice. 2023;16(1):119. DOI: 10.1186/s40545-023-00627-z. PMID 37814312 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Lo CWH, Pathadka S, Qin SX, et al. Neuropsychiatric events associated with montelukast in patients with asthma: a systematic review. European respiratory review : an official journal of the European Respiratory Society. 2023;32(169). DOI: 10.1183/16000617.0079-2023. PMID 37758273 — tags: [mild-and-moderate-asthma, red-flags-and-safety-concerns] — cited by: mild-and-moderate-asthma.md, red-flags-and-safety-concerns.md
• Scioscia G, Nolasco S, Campisi R, et al. Switching Biological Therapies in Severe Asthma. International journal of molecular sciences. 2023;24(11). DOI: 10.3390/ijms24119563. PMID 37298514 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Garin N, Zarate-Tamames B, Gras-Martin L, et al. Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis. Pharmaceuticals (Basel, Switzerland). 2023;16(3). DOI: 10.3390/ph16030414. PMID 36986513 — tags: [clinical-trials-landscape, inhaler-technique-adherence-and-self-management] — cited by: clinical-trials-landscape.md, inhaler-technique-adherence-and-self-management.md
• Akenroye AT, Segal JB, Zhou G, et al. Comparative effectiveness of omalizumab, mepolizumab, and dupilumab in asthma: A target trial emulation. The Journal of allergy and clinical immunology. 2023;151(5):1269-1276. DOI: 10.1016/j.jaci.2023.01.020. PMID 36740144 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Menzies-Gow A, Wechsler ME, Brightling CE, et al. Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study. The Lancet. Respiratory medicine. 2023;11(5):425-438. DOI: 10.1016/S2213-2600(22)00492-1. PMID 36702146 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Sun Y, Jariwala S, Reznik M. Measurement of adherence to inhaled corticosteroids by self-report and electronic medication monitoring. The Journal of asthma : official journal of the Association for the Care of Asthma. 2023;60(7):1299-1305. DOI: 10.1080/02770903.2022.2144352. PMID 36343353 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Lowden R, Turner S. Past asthma exacerbation in children predicting future exacerbation: a systematic review. ERJ open research. 2022;8(4). DOI: 10.1183/23120541.00174-2022. PMID 36382233 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Grennan KN, Maul TM, Nelson JS. Extracorporeal Life Support for Status Asthmaticus: Early Outcomes in Teens and Young Adults. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2022;68(10):1305-1311. DOI: 10.1097/MAT.0000000000001644. PMID 36194100 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Roche N, Aggarwal B, Boucot I, et al. The impact of inhaler technique on clinical outcomes in adolescents and adults with asthma: A systematic review. Respiratory medicine. 2022;202:106949. DOI: 10.1016/j.rmed.2022.106949. PMID 36063773 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Pilette C, Canonica GW, Chaudhuri R, et al. REALITI-A Study: Real-World Oral Corticosteroid-Sparing Effect of Mepolizumab in Severe Asthma. The journal of allergy and clinical immunology. In practice. 2022;10(10):2646-2656. DOI: 10.1016/j.jaip.2022.05.042. PMID 35753668 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Chan A, De Simoni A, Wileman V, et al. Digital interventions to improve adherence to maintenance medication in asthma. The Cochrane database of systematic reviews. 2022;6(6):CD013030. DOI: 10.1002/14651858.CD013030.pub2. PMID 35691614 — tags: [clinical-trials-landscape, inhaler-technique-adherence-and-self-management] — cited by: clinical-trials-landscape.md, inhaler-technique-adherence-and-self-management.md
• Papi A, Chipps BE, Beasley R, et al. Albuterol-Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma. The New England journal of medicine. 2022;386(22):2071-2083. DOI: 10.1056/NEJMoa2203163. PMID 35569035 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Beasley R, Harrison T, Peterson S, et al. Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients With Poorly Controlled Asthma: A Systematic Review and Meta-analysis. JAMA network open. 2022;5(3):e220615. DOI: 10.1001/jamanetworkopen.2022.0615. PMID 35230437 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Charles D, Shanley J, Temple SN, et al. Real-world efficacy of treatment with benralizumab, dupilumab, mepolizumab and reslizumab for severe asthma: A systematic review and meta-analysis. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2022;52(5):616-627. DOI: 10.1111/cea.14112. PMID 35174566 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Redmond C, Akinoso-Imran AQ, Heaney LG, et al. Socioeconomic disparities in asthma health care utilization, exacerbations, and mortality: A systematic review and meta-analysis. The Journal of allergy and clinical immunology. 2022;149(5):1617-1627. DOI: 10.1016/j.jaci.2021.10.007. PMID 34673047 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Reddel HK, Bacharier LB, Bateman ED, et al. Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes. American journal of respiratory and critical care medicine. 2022;205(1):17-35. DOI: 10.1164/rccm.202109-2205PP. PMID 34658302 — tags: [guidelines, mild-and-moderate-asthma] — cited by: guidelines.md, mild-and-moderate-asthma.md
• Wechsler ME, Ford LB, Maspero JF, et al. Long-term safety and efficacy of dupilumab in patients with moderate-to-severe asthma (TRAVERSE): an open-label extension study. The Lancet. Respiratory medicine. 2022;10(1):11-25. DOI: 10.1016/S2213-2600(21)00322-2. PMID 34597534 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Baggott C, Hardy JK, Sparks J, et al. Epinephrine (adrenaline) compared to selective beta-2-agonist in adults or children with acute asthma: a systematic review and meta-analysis. Thorax. 2022;77(6):563-572. DOI: 10.1136/thoraxjnl-2021-217124. PMID 34593615 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Bacharier LB, Maspero JF, Katelaris CH, et al. Dupilumab in Children with Uncontrolled Moderate-to-Severe Asthma. The New England journal of medicine. 2021;385(24):2230-2240. DOI: 10.1056/NEJMoa2106567. PMID 34879449 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Fidler A, Sweenie R, Ortega A, et al. Meta-Analysis of Adherence Promotion Interventions in Pediatric Asthma. Journal of pediatric psychology. 2021;46(10):1195-1212. DOI: 10.1093/jpepsy/jsab057. PMID 34343294 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Kim LHY, Saleh C, Whalen-Browne A, et al. Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis. JAMA. 2021;325(24):2466-2479. DOI: 10.1001/jama.2021.7872. PMID 34009257 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Crossingham I, Turner S, Ramakrishnan S, et al. Combination fixed-dose beta agonist and steroid inhaler as required for adults or children with mild asthma. The Cochrane database of systematic reviews. 2021;5(5):CD013518. DOI: 10.1002/14651858.CD013518.pub2. PMID 33945639 — tags: [asthma-in-children, mild-and-moderate-asthma] — cited by: asthma-in-children.md, mild-and-moderate-asthma.md
• Kim SH, Lee T, Jang AS, et al. Pragmatic Randomized Controlled Trial for Stepping Down Asthma Controller Treatment in Patients Controlled with Low-Dose Inhaled Corticosteroid and Long-Acting β2-Agonist: Step-Down of Intervention and Grade in Moderate Asthma Study. The journal of allergy and clinical immunology. In practice. 2021;9(10):3638-3646.e3. DOI: 10.1016/j.jaip.2021.04.042. PMID 33940213 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Chalitsios CV, Shaw DE, McKeever TM. Corticosteroids and bone health in people with asthma: A systematic review and meta-analysis. Respiratory medicine. 2021;181:106374. DOI: 10.1016/j.rmed.2021.106374. PMID 33799052 — tags: [comorbidity-and-mimics, red-flags-and-safety-concerns] — cited by: comorbidity-and-mimics.md, red-flags-and-safety-concerns.md
• Chao KY, Chien YH, Mu SC. High-flow nasal cannula in children with asthma exacerbation: A review of current evidence. Paediatric respiratory reviews. 2021;40:52-57. DOI: 10.1016/j.prrv.2021.01.003. PMID 33771473 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• FitzGerald JM, O'Byrne PM, Bateman ED, et al. Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies. Drug safety. 2021;44(4):467-478. DOI: 10.1007/s40264-020-01041-z. PMID 33548020 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Gupta RS, Fierstein JL, Boon KL, et al. Sensor-Based Electronic Monitoring for Asthma: A Randomized Controlled Trial. Pediatrics. 2021;147(1). DOI: 10.1542/peds.2020-1330. PMID 33386336 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Lee LA, Bailes Z, Barnes N, et al. Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial. The Lancet. Respiratory medicine. 2021;9(1):69-84. DOI: 10.1016/S2213-2600(20)30389-1. PMID 32918892 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Payares-Salamanca L, Contreras-Arrieta S, Florez-García V, et al. Metered-dose inhalers versus nebulization for the delivery of albuterol for acute exacerbations of wheezing or asthma in children: A systematic review with meta-analysis. Pediatric pulmonology. 2020;55(12):3268-3278. DOI: 10.1002/ppul.25077. PMID 32940961 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Price D, Castro M, Bourdin A, et al. Short-course systemic corticosteroids in asthma: striking the balance between efficacy and safety. European respiratory review : an official journal of the European Respiratory Society. 2020;29(155). DOI: 10.1183/16000617.0151-2019. PMID 32245768 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Bernstein JA, Virchow JC, Murphy K, et al. Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma: results from two phase 3, randomised, double-blind, placebo-controlled trials. The Lancet. Respiratory medicine. 2020;8(5):461-474. DOI: 10.1016/S2213-2600(19)30372-8. PMID 32066536 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Agache I, Beltran J, Akdis C, et al. Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines - recommendations on the use of biologicals in severe asthma. Allergy. 2020;75(5):1023-1042. DOI: 10.1111/all.14221. PMID 32034960 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Bleecker ER, Menzies-Gow AN, Price DB, et al. Systematic Literature Review of Systemic Corticosteroid Use for Asthma Management. American journal of respiratory and critical care medicine. 2020;201(3):276-293. DOI: 10.1164/rccm.201904-0903SO. PMID 31525297 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Janežič A, Locatelli I, Kos M. Inhalation technique and asthma outcomes with different corticosteroid-containing inhaler devices. The Journal of asthma : official journal of the Association for the Care of Asthma. 2020;57(6):654-662. DOI: 10.1080/02770903.2019.1591442. PMID 30915886 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Virchow JC, Kuna P, Paggiaro P, et al. Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials. Lancet (London, England). 2019;394(10210):1737-1749. DOI: 10.1016/S0140-6736(19)32215-9. PMID 31582314 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Hardy J, Baggott C, Fingleton J, et al. Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial. Lancet (London, England). 2019;394(10202):919-928. DOI: 10.1016/S0140-6736(19)31948-8. PMID 31451207 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Harris K, Kneale D, Lasserson T, et al. School-based asthma self-management interventions for children and adolescents with asthma. Paediatric respiratory reviews. 2019;31:40-42. DOI: 10.1016/j.prrv.2019.06.005. PMID 31422031 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Lazarus SC, Krishnan JA, King TS, et al. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. The New England journal of medicine. 2019;380(21):2009-2019. DOI: 10.1056/NEJMoa1814917. PMID 31112384 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
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• Khatri S, Moore W, Gibson PG, et al. Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma. The Journal of allergy and clinical immunology. 2019;143(5):1742-1751.e7. DOI: 10.1016/j.jaci.2018.09.033. PMID 30359681 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Busse W, Chupp G, Nagase H, et al. Anti-IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: Indirect treatment comparison. The Journal of allergy and clinical immunology. 2019;143(1):190-200.e20. DOI: 10.1016/j.jaci.2018.08.031. PMID 30205189 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Kocks JWH, Chrystyn H, van der Palen J, et al. Systematic review of association between critical errors in inhalation and health outcomes in asthma and COPD. NPJ primary care respiratory medicine. 2018;28(1):43. DOI: 10.1038/s41533-018-0110-x. PMID 30446655 — tags: [comorbidity-and-mimics, inhaler-technique-adherence-and-self-management] — cited by: comorbidity-and-mimics.md, inhaler-technique-adherence-and-self-management.md
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• Mes MA, Katzer CB, Chan AHY, et al. Pharmacists and medication adherence in asthma: a systematic review and meta-analysis. The European respiratory journal. 2018;52(2). DOI: 10.1183/13993003.00485-2018. PMID 29976652 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Normansell R, Sayer B, Waterson S, et al. Antibiotics for exacerbations of asthma. The Cochrane database of systematic reviews. 2018;6(6):CD002741. DOI: 10.1002/14651858.CD002741.pub2. PMID 29938789 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Rabe KF, Nair P, Brusselle G, et al. Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma. The New England journal of medicine. 2018;378(26):2475-2485. DOI: 10.1056/NEJMoa1804093. PMID 29782224 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Sobieraj DM, Weeda ER, Nguyen E, et al. Association of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma: A Systematic Review and Meta-analysis. JAMA. 2018;319(14):1485-1496. DOI: 10.1001/jama.2018.2769. PMID 29554195 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Heffler E, Madeira LNG, Ferrando M, et al. Inhaled Corticosteroids Safety and Adverse Effects in Patients with Asthma. The journal of allergy and clinical immunology. In practice. 2018;6(3):776-781. DOI: 10.1016/j.jaip.2018.01.025. PMID 29408385 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Usmani OS, Lavorini F, Marshall J, et al. Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes. Respiratory research. 2018;19(1):10. DOI: 10.1186/s12931-017-0710-y. PMID 29338792 — tags: [comorbidity-and-mimics, inhaler-technique-adherence-and-self-management] — cited by: comorbidity-and-mimics.md, inhaler-technique-adherence-and-self-management.md
• Laher AE, Buchanan SK. Mechanically Ventilating the Severe Asthmatic. Journal of intensive care medicine. 2018;33(9):491-501. DOI: 10.1177/0885066617740079. PMID 29105540 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Rogers L, Sugar EA, Blake K, et al. Step-Down Therapy for Asthma Well Controlled on Inhaled Corticosteroid and Long-Acting Beta-Agonist: A Randomized Clinical Trial. The journal of allergy and clinical immunology. In practice. 2018;6(2):633-643.e1. DOI: 10.1016/j.jaip.2017.07.030. PMID 28974349 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Barbara S, Kritikos V, Bosnic-Anticevich S. Inhaler technique: does age matter? A systematic review. European respiratory review : an official journal of the European Respiratory Society. 2017;26(146). DOI: 10.1183/16000617.0055-2017. PMID 29212836 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Kew KM, Malik P, Aniruddhan K, Normansell R. Shared decision-making for people with asthma. The Cochrane database of systematic reviews. 2017;10(10):CD012330. DOI: 10.1002/14651858.CD012330.pub2. PMID 28972652 — tags: [inhaler-technique-adherence-and-self-management, patient-experience-and-advocacy] — cited by: inhaler-technique-adherence-and-self-management.md, patient-experience-and-advocacy.md
• Nair P, Wenzel S, Rabe KF, et al. Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma. The New England journal of medicine. 2017;376(25):2448-2458. DOI: 10.1056/NEJMoa1703501. PMID 28530840 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Bravo-Soto GA, Harismendy C, Rojas P, et al. Is dexamethasone as effective as other corticosteroids for acute asthma exacerbation in children? Medwave. 2017;17(Suppl2):e6931. DOI: 10.5867/medwave.2017.6931. PMID 28430773 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Normansell R, Kew KM, Stovold E. Interventions to improve adherence to inhaled steroids for asthma. The Cochrane database of systematic reviews. 2017;4(4):CD012226. DOI: 10.1002/14651858.CD012226.pub2. PMID 28417456 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Gatheral TL, Rushton A, Evans DJ, et al. Personalised asthma action plans for adults with asthma. The Cochrane database of systematic reviews. 2017;4(4):CD011859. DOI: 10.1002/14651858.CD011859.pub2. PMID 28394084 — tags: [exacerbations-and-acute-care, inhaler-technique-adherence-and-self-management, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, inhaler-technique-adherence-and-self-management.md, red-flags-and-safety-concerns.md
• Chrystyn H, van der Palen J, Sharma R, et al. Device errors in asthma and COPD: systematic literature review and meta-analysis. NPJ primary care respiratory medicine. 2017;27(1):22. DOI: 10.1038/s41533-017-0016-z. PMID 28373682 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Pinnock H, Parke HL, Panagioti M, et al. Systematic meta-review of supported self-management for asthma: a healthcare perspective. BMC medicine. 2017;15(1):64. DOI: 10.1186/s12916-017-0823-7. PMID 28302126 — tags: [inhaler-technique-adherence-and-self-management, patient-experience-and-advocacy] — cited by: inhaler-technique-adherence-and-self-management.md, patient-experience-and-advocacy.md
• Normansell R, Kew KM, Mathioudakis AG. Interventions to improve inhaler technique for people with asthma. The Cochrane database of systematic reviews. 2017;3(3):CD012286. DOI: 10.1002/14651858.CD012286.pub2. PMID 28288272 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• D'Amato G, Vitale C, Molino A, et al. Asthma-related deaths. Multidisciplinary respiratory medicine. 2016;11:37. DOI: 10.1186/s40248-016-0073-0. PMID 27752310 — tags: [red-flags-and-safety-concerns] — cited by: red-flags-and-safety-concerns.md
• Gillette C, Rockich-Winston N, Kuhn JA, et al. Inhaler Technique in Children With Asthma: A Systematic Review. Academic pediatrics. 2016;16(7):605-15. DOI: 10.1016/j.acap.2016.04.006. PMID 27130811 — tags: [asthma-in-children, inhaler-technique-adherence-and-self-management] — cited by: asthma-in-children.md, inhaler-technique-adherence-and-self-management.md
• Pardue Jones B, Fleming GM, Otillio JK, et al. Pediatric acute asthma exacerbations: Evaluation and management from emergency department to intensive care unit. The Journal of asthma : official journal of the Association for the Care of Asthma. 2016;53(6):607-17. DOI: 10.3109/02770903.2015.1067323. PMID 27116362 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Pinnock H. Supported self-management for asthma. Breathe (Sheffield, England). 2015;11(2):98-109. DOI: 10.1183/20734735.015614. PMID 26306110 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Castro M, Zangrilli J, Wechsler ME, et al. Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials. The Lancet. Respiratory medicine. 2015;3(5):355-66. DOI: 10.1016/S2213-2600(15)00042-9. PMID 25736990 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Bårnes CB, Ulrik CS. Asthma and adherence to inhaled corticosteroids: current status and future perspectives. Respiratory care. 2015;60(3):455-68. DOI: 10.4187/respcare.03200. PMID 25118311 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Bel EH, Wenzel SE, Thompson PJ, et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. The New England journal of medicine. 2014;371(13):1189-97. DOI: 10.1056/NEJMoa1403291. PMID 25199060 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Schneider JE, Lewis LM, Ferguson I, et al. Repeated dyspnea score and percent FEV1 are modest predictors of hospitalization/relapse in patients with acute asthma exacerbation. Respiratory medicine. 2014;108(9):1284-91. DOI: 10.1016/j.rmed.2014.06.006. PMID 25087835 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Zhang HP, Jia CE, Lv Y, et al. Montelukast for prevention and treatment of asthma exacerbations in adults: Systematic review and meta-analysis. Allergy and asthma proceedings. 2014;35(4):278-87. DOI: 10.2500/aap.2014.35.3745. PMID 24992547 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Kew KM, Kirtchuk L, Michell CI. Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department. The Cochrane database of systematic reviews. 2014;2014(5):CD010909. DOI: 10.1002/14651858.CD010909.pub2. PMID 24865567 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Chung KF, Wenzel SE, Brozek JL, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. The European respiratory journal. 2014;43(2):343-73. DOI: 10.1183/09031936.00202013. PMID 24337046 — tags: [severe-asthma-and-biologics] — cited by: severe-asthma-and-biologics.md
• Lewis LM, Ferguson I, House SL, et al. Albuterol administration is commonly associated with increases in serum lactate in patients with asthma treated for acute exacerbation of asthma. Chest. 2014;145(1):53-59. DOI: 10.1378/chest.13-0930. PMID 23949578 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Goyal S, Agrawal A. Ketamine in status asthmaticus: A review. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2013;17(3):154-61. DOI: 10.4103/0972-5229.117048. PMID 24082612 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Jat KR, Khairwa A. Levalbuterol versus albuterol for acute asthma: a systematic review and meta-analysis. Pulmonary pharmacology & therapeutics. 2013;26(2):239-48. DOI: 10.1016/j.pupt.2012.11.003. PMID 23207739 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Rogers L, Reibman J. Stepping down asthma treatment: how and when. Current opinion in pulmonary medicine. 2012;18(1):70-5. DOI: 10.1097/MCP.0b013e32834db017. PMID 22081088 — tags: [mild-and-moderate-asthma] — cited by: mild-and-moderate-asthma.md
• Hodder R, Lougheed MD, Rowe BH, et al. Management of acute asthma in adults in the emergency department: nonventilatory management. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2010;182(2):E55-67. DOI: 10.1503/cmaj.080072. PMID 19858243 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Reddel HK, Taylor DR, Bateman ED, et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. American journal of respiratory and critical care medicine. 2009;180(1):59-99. DOI: 10.1164/rccm.200801-060ST. PMID 19535666 — tags: [exacerbations-and-acute-care, guidelines, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, guidelines.md, red-flags-and-safety-concerns.md
• Basheti IA, Reddel HK, Armour CL, Bosnic-Anticevich SZ. Improved asthma outcomes with a simple inhaler technique intervention by community pharmacists. The Journal of allergy and clinical immunology. 2007;119(6):1537-8. DOI: 10.1016/j.jaci.2007.02.037. PMID 17433831 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Pauwels RA, Pedersen S, Busse WW, et al. Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet (London, England). 2003;361(9363):1071-6. DOI: 10.1016/S0140-6736(03)12891-7. PMID 12672309 — tags: [clinical-trials-landscape, mild-and-moderate-asthma] — cited by: clinical-trials-landscape.md, mild-and-moderate-asthma.md
• Gibson PG, Powell H, Coughlan J, et al. Self-management education and regular practitioner review for adults with asthma. The Cochrane database of systematic reviews. 2003;(1):CD001117. DOI: 10.1002/14651858.CD001117. PMID 12535399 — tags: [inhaler-technique-adherence-and-self-management] — cited by: inhaler-technique-adherence-and-self-management.md
• Fulco PP, Lone AA, Pugh CB. Intravenous versus oral corticosteroids for treatment of acute asthma exacerbations. The Annals of pharmacotherapy. 2002;36(4):565-70. DOI: 10.1345/aph.1A107. PMID 11918500 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Baren JM, Shofer FS, Ivey B, et al. A randomized, controlled trial of a simple emergency department intervention to improve the rate of primary care follow-up for patients with acute asthma exacerbations. Annals of emergency medicine. 2001;38(2):115-22. DOI: 10.1067/mem.2001.116593. PMID 11468604 — tags: [exacerbations-and-acute-care, red-flags-and-safety-concerns] — cited by: exacerbations-and-acute-care.md, red-flags-and-safety-concerns.md
• Childhood Asthma Management Program Research Group, Szefler S, Weiss S, et al. Long-term effects of budesonide or nedocromil in children with asthma. The New England journal of medicine. 2000;343(15):1054-63. DOI: 10.1056/NEJM200010123431501. PMID 11027739 — tags: [asthma-in-children, mild-and-moderate-asthma] — cited by: asthma-in-children.md, mild-and-moderate-asthma.md
• Chassany O, Fullerton S. Meta-analysis of the effects of ipratropium bromide in adults with acute asthma. The American journal of medicine. 2000;108(7):596-7. DOI: 10.1016/s0002-9343(00)00298-9. PMID 10866596 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md
• Silverman R. Ipratropium bromide in emergency management of acute asthma exacerbation. Annals of emergency medicine. 2000;35(2):197-8. DOI: 10.1016/s0196-0644(00)70149-1. PMID 10650243 — tags: [exacerbations-and-acute-care] — cited by: exacerbations-and-acute-care.md

Life course, comorbidity and lived experience

• Murphy VE. Decreasing inhaled corticosteroids in pregnancy increases the risk for asthma exacerbations: time for new approaches to solve a decades-old problem. The European respiratory journal. 2025;66(6). DOI: 10.1183/13993003.01979-2025. PMID 41412710 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• Hatter L, Holliday M, Oldfield K, et al. Budesonide-formoterol versus salbutamol as reliever therapy in children with mild asthma (CARE): a 52-week, open-label, multicentre, superiority, randomised controlled trial. Lancet (London, England). 2025;406(10511):1473-1483. DOI: 10.1016/S0140-6736(25)00861-X. PMID 41033330 — tags: [asthma-in-children] — cited by: asthma-in-children.md
• McDonald CF. Patients' and Health Professionals' Views on Using Oral Corticosteroids for Asthma: Priorities, Trade-Offs and Shared Decision-Making. Respirology (Carlton, Vic.). 2025;30(11):1016-1017. DOI: 10.1111/resp.70102. PMID 40799034 — tags: [patient-experience-and-advocacy] — cited by: patient-experience-and-advocacy.md
• Gassasse Z, Khan ID, Mok E, et al. Association between income, employment status, and asthma outcomes: a systematic review and meta-analysis. The Lancet regional health. Europe. 2025;56:101367. DOI: 10.1016/j.lanepe.2025.101367. PMID 40688041 — tags: [patient-experience-and-advocacy] — cited by: patient-experience-and-advocacy.md
• Davis AE, Wechsler ME, Namazy JA, Schatz M. The safety of asthma treatment and management strategies in pregnancy. Expert review of respiratory medicine. 2025;19(10):1043-1054. DOI: 10.1080/17476348.2025.2522757. PMID 40536883 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• Matsuzaki H, Matsuzaki S, Ueda Y, et al. Obesity and asthma during pregnancy: a systematic review and meta-analysis. European respiratory review : an official journal of the European Respiratory Society. 2025;34(176). DOI: 10.1183/16000617.0259-2024. PMID 40500127 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• Pradhan A, Jayes L, Bains M, Martin MJ. Patient experience, understanding and self-management of asthma attacks: a qualitative study. The Journal of asthma : official journal of the Association for the Care of Asthma. 2025;62(5):872-880. DOI: 10.1080/02770903.2024.2449230. PMID 39773014 — tags: [patient-experience-and-advocacy] — cited by: patient-experience-and-advocacy.md
• Naftel J, Jackson DJ, Coleman M, et al. An international consensus on the use of asthma biologics in pregnancy. The Lancet. Respiratory medicine. 2025;13(1):80-91. DOI: 10.1016/S2213-2600(24)00174-7. PMID 39216499 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• Davis SR, Cvetkovski B, Katsoulotos GP, et al. The Path to Diagnosis of Severe Asthma-A Qualitative Exploration. International journal of general medicine. 2024;17:3601-3611. DOI: 10.2147/IJGM.S435347. PMID 39184910 — tags: [patient-experience-and-advocacy] — cited by: patient-experience-and-advocacy.md
• Fareed A, Siblini D, Vaid R, et al. Montelukast use in pregnancy: A systematic review and meta-analysis of maternal and fetal outcomes in asthma treatment. Congenital anomalies. 2024;64(6):220-227. DOI: 10.1111/cga.12581. PMID 39129058 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• Kang HQ, Pen Y, He Y, et al. The experience of shared decision-making for people with asthma: A systematic review and metasynthesis of qualitative studies. Health expectations : an international journal of public participation in health care and health policy. 2024;27(2):e14039. DOI: 10.1111/hex.14039. PMID 38613765 — tags: [patient-experience-and-advocacy] — cited by: patient-experience-and-advocacy.md
• Lee B, Turner S, Borland M, et al. Efficacy of oral corticosteroids for acute preschool wheeze: a systematic review and individual participant data meta-analysis of randomised clinical trials. The Lancet. Respiratory medicine. 2024;12(6):444-456. DOI: 10.1016/S2213-2600(24)00041-9. PMID 38527486 — tags: [asthma-in-children] — cited by: asthma-in-children.md
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• Schultz A, Brand PL. Episodic viral wheeze and multiple trigger wheeze in preschool children: a useful distinction for clinicians? Paediatric respiratory reviews. 2011;12(3):160-4. DOI: 10.1016/j.prrv.2011.01.008. PMID 21722843 — tags: [asthma-in-children] — cited by: asthma-in-children.md
• Rocklin RE. Asthma, asthma medications and their effects on maternal/fetal outcomes during pregnancy. Reproductive toxicology (Elmsford, N.Y.). 2011;32(2):189-97. DOI: 10.1016/j.reprotox.2011.05.023. PMID 21684328 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• American Lung Association Asthma Clinical Research Centers, Mastronarde JG, Anthonisen NR, et al. Efficacy of esomeprazole for treatment of poorly controlled asthma. The New England journal of medicine. 2009;360(15):1487-99. DOI: 10.1056/NEJMoa0806290. PMID 19357404 — tags: [comorbidity-and-mimics] — cited by: comorbidity-and-mimics.md
• To T, Gershon A, Wang C, et al. Persistence and remission in childhood asthma: a population-based asthma birth cohort study. Archives of pediatrics & adolescent medicine. 2007;161(12):1197-204. DOI: 10.1001/archpedi.161.12.1197. PMID 18056566 — tags: [asthma-in-children] — cited by: asthma-in-children.md
• Jaakkola JJ, Ahmed P, Ieromnimon A, et al. Preterm delivery and asthma: a systematic review and meta-analysis. The Journal of allergy and clinical immunology. 2006;118(4):823-30. DOI: 10.1016/j.jaci.2006.06.043. PMID 17030233 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md
• Guilbert TW, Morgan WJ, Zeiger RS, et al. Long-term inhaled corticosteroids in preschool children at high risk for asthma. The New England journal of medicine. 2006;354(19):1985-97. DOI: 10.1056/NEJMoa051378. PMID 16687711 — tags: [asthma-in-children, clinical-trials-landscape] — cited by: asthma-in-children.md, clinical-trials-landscape.md
• Dombrowski MP, Schatz M, Wise R, et al. Asthma during pregnancy. Obstetrics and gynecology. 2004;103(1):5-12. DOI: 10.1097/01.AOG.0000103994.75162.16. PMID 14704237 — tags: [pregnancy-and-reproductive-health] — cited by: pregnancy-and-reproductive-health.md

Guidelines and research frontier

• Sharafkhaneh A, Atayde ER, Cho J, et al. A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for the Primary Care Management of Asthma. Annals of internal medicine. 2026;179(4):564-573. DOI: 10.7326/ANNALS-25-03080. PMID 41698207 — tags: [guidelines] — cited by: guidelines/REGISTRY.md
• Gurgel RK, Baroody FM, Damask CC, et al. Clinical Practice Guideline: Immunotherapy for Inhalant Allergy. Otolaryngology--head and neck surgery. 2024;170 Suppl 1(Suppl 1):S1-S42. DOI: 10.1002/ohn.648. PMID 38408152 — tags: [guidelines] — cited by: guidelines/REGISTRY.md
• Khatri SB, Iaccarino JM, Barochia A, et al. Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline. American journal of respiratory and critical care medicine. 2021;204(10):e97-e109. DOI: 10.1164/rccm.202109-2093ST. PMID 34779751 — tags: [guidelines] — cited by: guidelines/REGISTRY.md
• Roberts G, Vazquez-Ortiz M, Knibb R, et al. EAACI Guidelines on the effective transition of adolescents and young adults with allergy and asthma. Allergy. 2020;75(11):2734-2752. DOI: 10.1111/all.14459. PMID 32558994 — tags: [guidelines] — cited by: guidelines/REGISTRY.md
• Agache I, Lau S, Akdis CA, et al. EAACI Guidelines on Allergen Immunotherapy: House dust mite-driven allergic asthma. Allergy. 2019;74(5):855-873. DOI: 10.1111/all.13749. PMID 31095767 — tags: [guidelines] — cited by: guidelines/REGISTRY.md
• Halken S, Larenas-Linnemann D, Roberts G, et al. EAACI guidelines on allergen immunotherapy: Prevention of allergy. Pediatric allergy and immunology. 2017;28(8):728-745. DOI: 10.1111/pai.12807. PMID 28902467 — tags: [guidelines] — cited by: guidelines/REGISTRY.md

• Lougheed MD, Lemiere C, Ducharme FM, et al. Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults. Canadian respiratory journal. 2012;19(2):127-164. DOI: 10.1155/2012/635624. PMID 22536582 — tags: [guidelines] — cited by: guidelines/REGISTRY.md

• Oberle AJ, Abbas F, Adrish M, et al. Biologic Management in Severe Asthma for Adults: An American College of Chest Physicians Clinical Practice Guideline. Chest. 2026;169(2):336-348. DOI: 10.1016/j.chest.2025.08.042. PMID 41005695 — tags: [guidelines] — cited by: guidelines.md

• White BR, Miller AG, Baker J, et al. AARC and PALISI Clinical Practice Guideline: Pediatric Critical Asthma. Respiratory care. 2025;70(5):593-609. DOI: 10.1089/respcare.12897. PMID 40323974 — tags: [guidelines] — cited by: guidelines.md
• British Thoracic Society (BTS), National Institute for Health and Care Excellence (NICE), Scottish Intercollegiate Guidelines Network (SIGN). BTS/NICE/SIGN joint guideline on asthma: diagnosis, monitoring and chronic asthma management (November 2024) - summary of recommendations. Thorax. 2025;80(7):416-424. DOI: 10.1136/thorax-2024-222910. PMID 40274410 — tags: [guidelines] — cited by: guidelines.md
• Dubin S, Patak P, Jung D. Update on Asthma Management Guidelines. Missouri medicine. 2024;121(5):364-367. PMID 39421468 — tags: [guidelines] — cited by: guidelines.md
• Ghanizada M, Jabarkhil A, Hansen S, et al. Biomarker defined infective and inflammatory asthma exacerbation phenotypes in hospitalized adults: clinical impact and phenotype stability at recurrent exacerbation. The Journal of asthma : official journal of the Association for the Care of Asthma. 2024;61(12):1715-1726. DOI: 10.1080/02770903.2024.2380510. PMID 39169832 — tags: [clinical-trials-landscape] — cited by: clinical-trials-landscape.md
• Zaeh SE, Eakin MN, Chupp G. Implementing Antiinflammatory Reliever Strategies in Asthma: The Evolving Paradigm of Asthma Management. Chest. 2024;165(2):250-252. DOI: 10.1016/j.chest.2023.09.004. PMID 38336438 — tags: [guidelines] — cited by: guidelines.md
• Ohnishi H, Otani T, Kanemitsu Y, et al. A systematic review and meta-analysis of macrolides in the management of adult patients with asthma. Allergology international : official journal of the Japanese Society of Allergology. 2024;73(3):382-389. DOI: 10.1016/j.alit.2024.01.002. PMID 38296770 — tags: [clinical-trials-landscape] — cited by: clinical-trials-landscape.md
• Krings JG, Beasley R. The Role of ICS-Containing Rescue Therapy Versus SABA Alone in Asthma Management Today. The journal of allergy and clinical immunology. In practice. 2024;12(4):870-879. DOI: 10.1016/j.jaip.2024.01.011. PMID 38237858 — tags: [guidelines] — cited by: guidelines.md
• Levy ML, Bacharier LB, Bateman E, et al. Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update. NPJ primary care respiratory medicine. 2023;33(1):7. DOI: 10.1038/s41533-023-00330-1. PMID 36754956 — tags: [guidelines] — cited by: guidelines.md
• Chipps BE, Murphy KR, Oppenheimer J. 2020 NAEPP Guidelines Update and GINA 2021-Asthma Care Differences, Overlap, and Challenges. The journal of allergy and clinical immunology. In practice. 2022;10(1S):S19-S30. DOI: 10.1016/j.jaip.2021.10.032. PMID 34718214 — tags: [guidelines] — cited by: guidelines.md
• Murphy KR, Solis J. National Asthma Education and Prevention Program 2020 Guidelines: What's Important for Primary Care. The Journal of family practice. 2021;70(6S):S19-S28. DOI: 10.12788/jfp.0219. PMID 34432620 — tags: [guidelines] — cited by: guidelines.md
• Cloutier MM, Dixon AE, Krishnan JA, et al. Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the National Asthma Education and Prevention Program. JAMA. 2020;324(22):2301-2317. DOI: 10.1001/jama.2020.21974. PMID 33270095 — tags: [guidelines] — cited by: guidelines.md
• Wang E, Wechsler ME, Tran TN, et al. Characterization of Severe Asthma Worldwide: Data From the International Severe Asthma Registry. Chest. 2020;157(4):790-804. DOI: 10.1016/j.chest.2019.10.053. PMID 31785254 — tags: [clinical-trials-landscape] — cited by: clinical-trials-landscape.md
• Holguin F, Cardet JC, Chung KF, et al. Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline. The European respiratory journal. 2020;55(1). DOI: 10.1183/13993003.00588-2019. PMID 31558662 — tags: [guidelines] — cited by: guidelines.md
• Drake SM, Simpson A, Fowler SJ. Asthma Diagnosis: The Changing Face of Guidelines. Pulmonary therapy. 2019;5(2):103-115. DOI: 10.1007/s41030-019-0093-y. PMID 32026404 — tags: [guidelines] — cited by: guidelines.md
• Edris A, De Feyter S, Maes T, et al. Monoclonal antibodies in type 2 asthma: a systematic review and network meta-analysis. Respiratory research. 2019;20(1):179. DOI: 10.1186/s12931-019-1138-3. PMID 31395084 — tags: [clinical-trials-landscape] — cited by: clinical-trials-landscape.md
• Keeley D, Baxter N. Conflicting asthma guidelines cause confusion in primary care. BMJ (Clinical research ed.). 2018;360:k29. DOI: 10.1136/bmj.k29. PMID 29317387 — tags: [guidelines] — cited by: guidelines.md
• Gibson PG, Yang IA, Upham JW, et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. Lancet (London, England). 2017;390(10095):659-668. DOI: 10.1016/S0140-6736(17)31281-3. PMID 28687413 — tags: [clinical-trials-landscape] — cited by: clinical-trials-landscape.md
• Reddel HK, Levy ML, Global Initiative for Asthma Scientific Committee and Dissemination and Implementation Committee. The GINA asthma strategy report: what's new for primary care? NPJ primary care respiratory medicine. 2015;25:15050. DOI: 10.1038/npjpcrm.2015.50. PMID 26224549 — tags: [guidelines] — cited by: guidelines.md
• British Thoracic Society, Scottish Intercollegiate Guidelines Network. British guideline on the management of asthma. Thorax. 2014;69 Suppl 1:1-192. PMID 25323740 — tags: [guidelines] — cited by: guidelines.md
• Reddel HK, Hurd SS, FitzGerald JM. World Asthma Day. GINA 2014: a global asthma strategy for a global problem. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2014;18(5):505-6. DOI: 10.5588/ijtld.14.0246. PMID 24903781 — tags: [guidelines] — cited by: guidelines.md
• Reddy AP, Gupta MR. Management of asthma: the current US and European guidelines. Advances in experimental medicine and biology. 2014;795:81-103. DOI: 10.1007/978-1-4614-8603-9_6. PMID 24162904 — tags: [guidelines] — cited by: guidelines.md
• Parsons JP, Hallstrand TS, Mastronarde JG, et al. An official American Thoracic Society clinical practice guideline: exercise-induced bronchoconstriction. American journal of respiratory and critical care medicine. 2013;187(9):1016-27. DOI: 10.1164/rccm.201303-0437ST. PMID 23634861 — tags: [guidelines] — cited by: guidelines.md
• Hanania NA, Alpan O, Hamilos DL, et al. Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial. Annals of internal medicine. 2011;154(9):573-82. DOI: 10.7326/0003-4819-154-9-201105030-00002. PMID 21536936 — tags: [clinical-trials-landscape] — cited by: clinical-trials-landscape.md
• Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. The European respiratory journal. 2008;31(1):143-78. DOI: 10.1183/09031936.00138707. PMID 18166595 — tags: [guidelines] — cited by: guidelines.md
• National Asthma Education and Prevention Program. Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. The Journal of allergy and clinical immunology. 2007;120(5 Suppl):S94-138. DOI: 10.1016/j.jaci.2007.09.043. PMID 17983880 — tags: [guidelines] — cited by: guidelines.md
• National Heart, Lung, and Blood Institute, National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. The Journal of allergy and clinical immunology. 2005;115(1):34-46. DOI: 10.1016/j.jaci.2004.10.023. PMID 15637545 — tags: [guidelines] — cited by: guidelines.md