Bibliography — type 1 diabetes¶

Last curated: 2026-08-30

259 unique PubMed records cited across the canonical wiki pages. Every PMID was resolved through live PubMed E-utilities during the 2026-08-28 build, 2026-08-30 deepening session, or 2026-08-30 audit.

Overview and burden¶

Livingstone SJ, et al. Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010. JAMA. 2015;313:37-44. PMID 25562264 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, overview.md
Raab J, et al. Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: design and initial results of the Fr1da study. BMJ Open. 2016. PMID 27194320 — tags: [overview-burden] — cited by: overview.md, screening-and-early-detection.md, staging-and-natural-history.md
Foster NC, et al. State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016-2018. Diabetes Technol Ther. 2019;21:66-72. PMID 30657336 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, guidelines.md, insulin-therapy-and-technology.md, overview.md, psychosocial-and-behavioral.md
Ziegler AG, et al. Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany. JAMA. 2020;323:339-351. PMID 31990315 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, guidelines.md, overview.md, screening-and-early-detection.md, staging-and-natural-history.md
Zhang Y, et al. Fear of hypoglycemia in patients with type 1 and 2 diabetes: a systematic review. J Clin Nurs. 2020. PMID 33091198 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, hypoglycemia.md, overview.md, patient-experience-and-advocacy.md
Gregory GA, et al. Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040. Lancet Diabetes Endocrinol. 2022;10:741-760. PMID 36113507 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, genetics-and-environmental-triggers.md, overview.md, patient-experience-and-advocacy.md, staging-and-natural-history.md
GBD 2021 Diabetes Collaborators. Global, regional, and national burden of diabetes from 1990 to 2021, with projections to 2050. Lancet. 2023;402:203-234. PMID 37356446 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, overview.md
Embick R, et al. The impact of stigma on the management of type 1 diabetes: A systematic review. Diabet Med. 2024;41:e15299. PMID 38361327 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Yang Q, et al. Real-world glycaemic outcomes of automated insulin delivery in type 1 diabetes: A meta-analysis. Diabetes Obes Metab. 2024;26:3753-3763. PMID 38888056 — tags: [overview-burden] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md, epidemiology-and-burden.md, insulin-therapy-and-technology.md
American Diabetes Association Professional Practice Committee. 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes-2026. Diabetes Care. 2026. PMID 41358893 — tags: [overview-burden] — cited by: guidelines.md, overview.md
American Diabetes Association Professional Practice Committee. Summary of Revisions: Standards of Care in Diabetes-2026. Diabetes Care. 2026. PMID 41358896 — tags: [overview-burden] — cited by: overview.md
American Diabetes Association Professional Practice Committee. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2026. Diabetes Care. 2026. PMID 41358900 — tags: [overview-burden] — cited by: overview.md
Zhang T, et al. Worldwide prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes: A systematic review and meta-analysis. Prev Med. 2026;210:108625. PMID 42303108 — tags: [overview-burden] — cited by: epidemiology-and-burden.md, overview.md, red-flags-and-safety-concerns.md, screening-and-early-detection.md
Peprah Osei E, et al. Global prevalence and correlates of diabetes distress in type 1 diabetes: A systematic review and meta-analysis. Diabetes Res Clin Pract. 2026;239:113452. PMID 42486409 — tags: [overview-burden] — cited by: overview.md, patient-experience-and-advocacy.md, psychosocial-and-behavioral.md

Natural history and screening¶

Mechanism, genetics, and biomarkers¶

Palmer JP, et al. C-peptide is the appropriate outcome measure for T1D trials. Diabetes. 2004;53:250-264. PMID 14693724 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, disease-modifying-immunotherapy.md
Barrett JC, et al. GWAS identifies over 40 T1D loci. Nat Genet. 2009;41:703-707. PMID 19430480 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md
Noble JA, Erlich HA. Genetics of type 1 diabetes. Cold Spring Harb Perspect Med. 2012;2:a007732. PMID 22315720 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md
Gupta S. Immunotherapies in diabetes mellitus type 1. Med Clin North Am. 2012;96:621-634. PMID 22703858 — tags: [mechanism-genetics-biomarkers] — cited by: immunopathogenesis.md
Ziegler AG, et al. Seroconversion to multiple islet autoantibodies and progression. JAMA. 2013;309:2473-2479. PMID 23780460 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, overview.md, screening-and-early-detection.md, staging-and-natural-history.md
Usmani-Brown S, et al. Analysis of β-cell death by droplet digital PCR. Endocrinology. 2014;155:3694-3698. PMID 25004096 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md
Tomlinson MJ, et al. Fine mapping at chromosome 16p13.13. Diabetes. 2014;63:4360-4368. PMID 25008175 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md
Insel RA, et al. Staging presymptomatic T1D. Diabetes Care. 2015;38:1964-1974. PMID 26404926 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, guidelines.md, overview.md, screening-and-early-detection.md, staging-and-natural-history.md
Willcox A, et al. Histology of Type 1 Diabetes Pancreas. Methods Mol Biol. 2016;1433:105-117. PMID 26801316 — tags: [mechanism-genetics-biomarkers] — cited by: immunopathogenesis.md
Pugliese A, et al. Protective HLA haplotype in autoantibody-positive relatives. Diabetes. 2016;65:1109-1119. PMID 26822082 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md
Pugliese A. Insulitis in the pathogenesis of type 1 diabetes. Pediatr Diabetes. 2016;17 Suppl 22:31-36. PMID 27411434 — tags: [mechanism-genetics-biomarkers] — cited by: immunopathogenesis.md
Lönnrot M, et al. Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity. Diabetologia. 2017;60:1931-1940. PMID 28770319 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md, immunopathogenesis.md, staging-and-natural-history.md
Allen DW, et al. Maternal virus infections in pregnancy and type 1 diabetes in their offspring. Rev Med Virol. 2018;28:e1974. PMID 29569297 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md
Shields BM, et al. C-Peptide Decline in T1D Has Two Phases. Diabetes Care. 2018;41:1486-1492. PMID 29880650 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, immunopathogenesis.md, staging-and-natural-history.md
Ovalle F, et al. Verapamil and beta cell function in adults with recent-onset type 1 diabetes. Nat Med. 2018;24:1108-1112. PMID 29988125 — tags: [mechanism-genetics-biomarkers] — cited by: immunopathogenesis.md, overview.md
Rodriguez-Calvo T, et al. Pancreas Pathology During the Natural History of Type 1 Diabetes. Curr Diab Rep. 2018;18:124. PMID 30293191 — tags: [mechanism-genetics-biomarkers] — cited by: immunopathogenesis.md
Vatanen T, et al. The human gut microbiome in early-onset type 1 diabetes from the TEDDY study. Nature. 2018;562:589-594. PMID 30356183 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md
Stewart CJ, et al. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 2018;562:583-588. PMID 30356187 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md
Sharp SA, et al. Improved Type 1 Diabetes Genetic Risk Score. Diabetes Care. 2019;42:200-207. PMID 30655379 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, epidemiology-and-burden.md, genetics-and-environmental-triggers.md, screening-and-early-detection.md
Lin A, et al. Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report. Diabetes. 2021;70:1123-1129. PMID 33632742 — tags: [mechanism-genetics-biomarkers] — cited by: disease-modifying-immunotherapy.md, immunopathogenesis.md
Weiss A, et al. Progression likelihood score. Diabetologia. 2022;65:2121-2131. PMID 36028774 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, clinical-trials-landscape.md, overview.md, screening-and-early-detection.md, staging-and-natural-history.md
McVean J, et al. Effect of Tight Glycemic Control on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes. JAMA. 2023;329:980-989. PMID 36826834 — tags: [mechanism-genetics-biomarkers] — cited by: clinical-trials-landscape.md, disease-modifying-immunotherapy.md, immunopathogenesis.md, insulin-therapy-and-technology.md, overview.md
Isaacs SR, et al. Enteroviruses and risk of islet autoimmunity or type 1 diabetes. Lancet Diabetes Endocrinol. 2023;11:578-592. PMID 37390839 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md, immunopathogenesis.md, overview.md
Atkinson MA, et al. The pathogenic “symphony” in type 1 diabetes. Cell Metab. 2023;35:1500-1518. PMID 37478842 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md, immunopathogenesis.md, staging-and-natural-history.md
Phillip M, et al. Monitoring IAb-Positive Pre-Stage 3 T1D. Diabetes Care. 2024;47:1276-1298. PMID 38912694 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, guidelines.md, overview.md, patient-experience-and-advocacy.md, screening-and-early-detection.md, staging-and-natural-history.md
Bonifacio E, et al. Type 1 diabetes risk factors, risk prediction and presymptomatic detection. Diabetes Obes Metab. 2025;27 Suppl 6:28-39. PMID 40134221 — tags: [mechanism-genetics-biomarkers] — cited by: genetics-and-environmental-triggers.md
Evans-Molina C, et al. T1D presenting in adults. Diabetes Obes Metab. 2025. PMID 40230204 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, epidemiology-and-burden.md, genetics-and-environmental-triggers.md, red-flags-and-safety-concerns.md, staging-and-natural-history.md
Hu J, et al. A type 1 diabetes genetic risk score discriminates between type 1 diabetes and type 2 diabetes in a Chinese population. Diabetologia. 2025;68:1969-1982. PMID 40569436 — tags: [mechanism-genetics-biomarkers] — cited by: biomarkers.md, genetics-and-environmental-triggers.md, screening-and-early-detection.md
Low ZY, et al. Vitamin supplementation and its effect on incident type 1 diabetes mellitus and islet autoimmunity: a systematic review and meta-analysis. Front Immunol. 2025;16:1505324. PMID 40270966 — tags: [environment, prevention, vitamin-d] — cited by: genetics-and-environmental-triggers.md

Insulin and technology¶

Beck RW, et al. Effect of Continuous Glucose Monitoring on Glycemic Control in Adults Using Insulin Injections. JAMA. 2017;317:371-378. PMID 28118453 — tags: [insulin-technology] — cited by: guidelines.md, insulin-therapy-and-technology.md
Oskarsson P, et al. Impact of flash glucose monitoring on hypoglycaemia in adults using injections. Diabetologia. 2018;61:539-550. PMID 29273897 — tags: [insulin-technology] — cited by: insulin-therapy-and-technology.md
Agarwal S, et al. Racial-Ethnic Disparities in Diabetes Technology Use Among Young Adults. Diabetes Technol Ther. 2021;23:306-313. PMID 33155826 — tags: [insulin-technology] — cited by: insulin-therapy-and-technology.md, patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Fantasia KL, et al. Racial Disparities in Diabetes Technology Use and Outcomes in a Safety-Net Hospital. J Diabetes Sci Technol. 2021;15:1010-1017. PMID 33719610 — tags: [insulin-technology] — cited by: insulin-therapy-and-technology.md, patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Ware J, et al. Randomized Trial of Closed-Loop Control in Very Young Children. N Engl J Med. 2022;386:209-219. PMID 35045227 — tags: [insulin-technology] — cited by: insulin-therapy-and-technology.md
Kruger D, et al. Multicenter Randomized Trial of the Insulin-Only Bionic Pancreas in Adults. Diabetes Technol Ther. 2022;24:697-711. PMID 36173236 — tags: [insulin-technology] — cited by: insulin-therapy-and-technology.md

Disease modification¶

Pescovitz MD, et al. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. N Engl J Med. 2009;361:2143-2152. PMID 19940299 — tags: [disease-modification] — cited by: disease-modifying-immunotherapy.md
Orban T, et al. Co-stimulation modulation with abatacept in recent-onset type 1 diabetes. Lancet. 2011;378:412-419. PMID 21719096 — tags: [disease-modification] — cited by: disease-modifying-immunotherapy.md
Haller MJ, et al. Low-Dose ATG Preserves β-Cell Function and Improves HbA1c. Diabetes Care. 2018;41:1917-1925. PMID 30012675 — tags: [disease-modification] — cited by: clinical-trials-landscape.md, disease-modifying-immunotherapy.md
Forlenza GP, et al. Effect of Verapamil on Pancreatic Beta Cell Function. JAMA. 2023;329:990-999. PMID 36826844 — tags: [disease-modification] — cited by: clinical-trials-landscape.md, disease-modifying-immunotherapy.md, immunopathogenesis.md, overview.md
Ramos EL, et al. Teplizumab and β-Cell Function in Newly Diagnosed Type 1 Diabetes. N Engl J Med. 2023;389:2151-2161. PMID 37861217 — tags: [disease-modification] — cited by: disease-modifying-immunotherapy.md, immunopathogenesis.md, overview.md
Piemonti L, et al. Induction of immune education in type 1 diabetes through controlled allogeneic islet rejection at onset: a monocentric open-label pilot study. EClinicalMedicine. 2025;90:103685. PMID 41438972 — tags: [disease-modification, tolerance] — cited by: disease-modifying-immunotherapy.md, immunopathogenesis.md

Cell replacement¶

Hering BJ, et al. Phase 3 Trial of Transplantation of Human Islets in T1D Complicated by Severe Hypoglycemia. Diabetes Care. 2016;39:1230-1240. PMID 27208344 — tags: [cell-replacement] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md
Foster ED, et al. Improved Health-Related Quality of Life in a Phase 3 Islet Transplantation Trial. Diabetes Care. 2018;41:1001-1008. PMID 29563196 — tags: [cell-replacement] — cited by: beta-cell-replacement.md
Brown SA, et al. Six-Month Randomized, Multicenter Trial of Closed-Loop Control. N Engl J Med. 2019;381:1707-1717. PMID 31618560 — tags: [cell-replacement] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md, complications.md, epidemiology-and-burden.md, guidelines.md, hypoglycemia.md, insulin-therapy-and-technology.md, overview.md
Ramzy A, et al. Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide. Cell Stem Cell. 2021;28:2047-2061.e5. PMID 34861146 — tags: [cell-replacement] — cited by: beta-cell-replacement.md
Reichman TW, et al. Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes. N Engl J Med. 2025;393:858-868. PMID 40544428 — tags: [cell-replacement] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md, overview.md

Acute safety¶

Riddell MC, et al. Exercise management in type 1 diabetes. Lancet Diabetes Endocrinol. 2017;5:377-390. PMID 28126459 — tags: [acute-safety] — cited by: red-flags-and-safety-concerns.md
Rickels MR. Hypoglycemia-associated autonomic failure and therapeutic options. Ann N Y Acad Sci. 2019;1454:68-79. PMID 31389033 — tags: [acute-safety] — cited by: guidelines.md, hypoglycemia.md, red-flags-and-safety-concerns.md
Matsuhisa M, et al. Nasal glucagon for insulin-induced hypoglycaemia. Diabetes Obes Metab. 2020;22:1167-1175. PMID 32115879 — tags: [acute-safety] — cited by: hypoglycemia.md
Pieber TR, et al. Dasiglucagon for Severe Hypoglycemia. Diabetes Care. 2021;44:1361-1367. PMID 35239971 — tags: [acute-safety] — cited by: hypoglycemia.md, red-flags-and-safety-concerns.md
Amiel SA, et al. Hypoglycaemia Awareness Restoration Programme randomized trial. Nat Commun. 2022;13:2229. PMID 35484106 — tags: [acute-safety] — cited by: hypoglycemia.md
Ali N, et al. Fall in prevalence of impaired awareness of hypoglycaemia. Diabet Med. 2023. PMID 36645139 — tags: [acute-safety] — cited by: hypoglycemia.md, overview.md
Zammitt NN, et al. Predictors of impaired awareness and severe hypoglycaemia. Diabet Med. 2025. PMID 40386839 — tags: [acute-safety] — cited by: complications.md, hypoglycemia.md, overview.md, red-flags-and-safety-concerns.md

Complications¶

DCCT Research Group. Effect of intensive treatment on long-term complications. N Engl J Med. 1993;329:977-986. PMID 8366922 — tags: [complications] — cited by: complications.md, guidelines.md, insulin-therapy-and-technology.md, overview.md
Nathan DM, et al. Intensive diabetes treatment and cardiovascular disease. N Engl J Med. 2005;353:2643-2653. PMID 16371630 — tags: [complications] — cited by: complications.md
Cengiz E, et al. Severe hypoglycemia and DKA among youth in T1D Exchange. Pediatr Diabetes. 2013;14:447-454. PMID 23469984 — tags: [complications] — cited by: complications.md, hypoglycemia.md
DCCT/EDIC Study Research Group. Intensive Diabetes Treatment and Cardiovascular Outcomes: 30-Year Follow-up. Diabetes Care. 2016. PMID 26861924 — tags: [complications] — cited by: complications.md, overview.md
Rawshani A, et al. Mortality and Cardiovascular Disease in Type 1 and Type 2 Diabetes. N Engl J Med. 2017. PMID 28402770 — tags: [complications] — cited by: complications.md, epidemiology-and-burden.md, overview.md
DCCT/EDIC Research Group, et al. Frequency of Evidence-Based Screening for Retinopathy. N Engl J Med. 2017;376:1507-1516. PMID 28423305 — tags: [complications] — cited by: complications.md
Rawshani A, et al. Excess mortality and cardiovascular disease by age at onset. Lancet. 2018;392:477-486. PMID 30129464 — tags: [complications] — cited by: complications.md, epidemiology-and-burden.md, overview.md

Psychosocial and patient experience¶

Whittemore R, et al. Psychological experience of parents of children with T1D. Diabetes Educ. 2012;38:562-579. PMID 22581804 — tags: [psychosocial-patient-experience] — cited by: patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Hanlan ME, et al. Eating Disorders and Disordered Eating in T1D. Curr Diab Rep. 2013. PMID 24022608 — tags: [psychosocial-patient-experience] — cited by: psychosocial-and-behavioral.md
Peterson CM, et al. Comprehensive risk model for disordered eating in youth with T1D. J Pediatr Psychol. 2015;40:385-390. PMID 25502449 — tags: [psychosocial-patient-experience] — cited by: psychosocial-and-behavioral.md
Garvey KC, et al. Health Care Transition in Young Adults With T1D. Diabetes Care. 2016;39:190-197. PMID 26681724 — tags: [psychosocial-patient-experience] — cited by: psychosocial-and-behavioral.md
Fisher L, et al. Diabetes distress in adults with T1D. J Diabetes Complications. 2016;30:1123-1128. PMID 27118163 — tags: [psychosocial-patient-experience] — cited by: psychosocial-and-behavioral.md
Campbell F, et al. Transition of care from paediatric to adult services. Cochrane Database Syst Rev. 2016;4:CD009794. PMID 27128768 — tags: [psychosocial-patient-experience] — cited by: psychosocial-and-behavioral.md
Pulungan AB, et al. Availability and access to pediatric diabetes care. Clin Pediatr Endocrinol. 2023;32:137-146. PMID 37362165 — tags: [psychosocial-patient-experience] — cited by: patient-experience-and-advocacy.md
Lakshman R, et al. Lived Experience of Fully Closed-Loop Insulin Delivery. Diabetes Technol Ther. 2024;26:211-221. PMID 38426909 — tags: [psychosocial-patient-experience] — cited by: patient-experience-and-advocacy.md, psychosocial-and-behavioral.md

Guidelines¶

Lindholm Olinder A, et al. ISPAD Clinical Practice Consensus Guidelines 2022: Diabetes education in children and adolescents. Pediatr Diabetes. 2022;23:1229-1242. PMID 36120721 — tags: [guidelines, education] — cited by: guidelines.md
Danne T, et al. Consensus on DKA Risk Management With SGLT Inhibitors. Diabetes Care. 2019;42:1147-1154. PMID 30728224 — tags: [guidelines] — cited by: guidelines.md, red-flags-and-safety-concerns.md
Battelino T, et al. Clinical Targets for CGM Data Interpretation. Diabetes Care. 2019;42:1593-1603. PMID 31177185 — tags: [guidelines] — cited by: guidelines.md, insulin-therapy-and-technology.md, overview.md
Glaser N, et al. ISPAD 2022: DKA and hyperglycemic hyperosmolar state. Pediatr Diabetes. 2022;23:835-856. PMID 36250645 — tags: [guidelines] — cited by: guidelines.md, red-flags-and-safety-concerns.md
de Wit M, et al. ISPAD 2022: Psychological care. Pediatr Diabetes. 2022;23:1373-1389. PMID 36464988 — tags: [guidelines] — cited by: guidelines.md
Adolfsson P, et al. ISPAD 2022: Exercise. Pediatr Diabetes. 2022;23:1341-1372. PMID 36537529 — tags: [guidelines] — cited by: guidelines.md, red-flags-and-safety-concerns.md
Bjornstad P, et al. ISPAD 2022: Microvascular and macrovascular complications. Pediatr Diabetes. 2022;23:1432-1450. PMID 36537531 — tags: [guidelines] — cited by: guidelines.md
Abraham MB, et al. ISPAD Clinical Practice Consensus Guidelines 2022: Assessment and management of hypoglycemia in children and adolescents with diabetes. Pediatr Diabetes. 2022;23:1322-1340. PMID 36537534 — tags: [guidelines, hypoglycemia] — cited by: guidelines.md
Haller MJ, et al. ISPAD 2024: Screening, Staging, and β-Cell Preservation. Horm Res Paediatr. 2024;97:529-545. PMID 39662065 — tags: [guidelines] — cited by: guidelines.md, staging-and-natural-history.md
de Bock M, et al. ISPAD 2024: Glycemic Targets. Horm Res Paediatr. 2024;97:546-554. PMID 39701064 — tags: [guidelines] — cited by: guidelines.md
ADA Professional Practice Committee. Diabetes Technology: Standards of Care in Diabetes—2026. Diabetes Care. 2026. PMID 41358889 — tags: [guidelines] — cited by: guidelines.md, overview.md

Clinical trials¶

TrialNet Oral Insulin Study Group. Oral Insulin Prevention Trial. JAMA. 2017;318:1891-1902. PMID 29164254 — tags: [clinical-trials] — cited by: clinical-trials-landscape.md, disease-modifying-immunotherapy.md
Herold KC, et al. Teplizumab in Relatives at Risk. N Engl J Med. 2019;381:603-613. PMID 31180194 — tags: [clinical-trials] — cited by: biomarkers.md, clinical-trials-landscape.md, disease-modifying-immunotherapy.md, immunopathogenesis.md, overview.md, screening-and-early-detection.md, staging-and-natural-history.md
Russell WE, et al. Abatacept for Stage-1 Progression. Diabetes Care. 2023;46:1005-1013. PMID 36920087 — tags: [clinical-trials] — cited by: biomarkers.md, clinical-trials-landscape.md, disease-modifying-immunotherapy.md, immunopathogenesis.md, staging-and-natural-history.md
Zeng B, et al. AID in Children and Adolescents. Diabetes Care. 2023. PMID 38011519 — tags: [clinical-trials] — cited by: clinical-trials-landscape.md, insulin-therapy-and-technology.md, overview.md
Di Molfetta S, et al. Hybrid Closed Loop Network Meta-analysis. Diabetes Metab Res Rev. 2024. PMID 39298688 — tags: [clinical-trials] — cited by: clinical-trials-landscape.md, guidelines.md, insulin-therapy-and-technology.md, overview.md
Canha D, et al. AID and diabetes distress. Diabet Med. 2025. PMID 39726162 — tags: [clinical-trials] — cited by: clinical-trials-landscape.md, hypoglycemia.md, overview.md, patient-experience-and-advocacy.md, psychosocial-and-behavioral.md

2026-08-30 deepening additions¶

These records were added during the page-by-page deepening pass. The section is chronological and deduplicated by PMID; topical tags remain searchable through the citing-page field.

Wibell L, et al. Increased mortality in diabetes during the first 10 years. J Intern Med. 2001;249:263-270. PMID 11285046 — tags: [2026-deepening] — cited by: hypoglycemia.md
Hviid A, et al. Childhood vaccination and type 1 diabetes. N Engl J Med. 2004;350:1398-1404. PMID 15070789 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Barker JM, et al. Prediction of autoantibody positivity and progression to type 1 diabetes: DAISY. J Clin Endocrinol Metab. 2004;89:3896-3902. PMID 15292324 — tags: [2026-deepening] — cited by: screening-and-early-detection.md, staging-and-natural-history.md
Dagogo-Jack S. Hypoglycemia in type 1 diabetes mellitus: pathophysiology and prevention. Treat Endocrinol. 2004;3:91-103. PMID 15743105 — tags: [2026-deepening] — cited by: hypoglycemia.md
Genuth S. Insights from DCCT/EDIC on intensive glycemic treatment and complications. Endocr Pract. 2006;12 Suppl 1:34-41. PMID 16627378 — tags: [2026-deepening] — cited by: complications.md
Zipitis CS, Akobeng AK. Vitamin D supplementation in early childhood and risk of type 1 diabetes. Arch Dis Child. 2008;93:512-517. PMID 18339654 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Cure P, et al. Islet after kidney transplantation: metabolic control and quality of life. Transplantation. 2008;85:801-812. PMID 18360260 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Gangemi A, et al. Islet transplantation for brittle type 1 diabetes: the UIC protocol. Am J Transplant. 2008;8:1250-1261. PMID 18444920 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Bonifacio E, et al. Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays. J Clin Endocrinol Metab. 2010;95:3360-3367. PMID 20444913 — tags: [2026-deepening] — cited by: screening-and-early-detection.md
Bruno G, et al. Age-period-cohort analysis of childhood diabetes in Italy. Diabetes. 2010;59:2281-2287. PMID 20566665 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md
Posselt AM, et al. Islet transplantation using an efalizumab-based protocol. Am J Transplant. 2010;10:1870-1880. PMID 20659093 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Bingley PJ, et al. Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium. Clin Trials. 2010;7:S56-S64. PMID 20693189 — tags: [2026-deepening] — cited by: screening-and-early-detection.md
Campbell LK, et al. Neurocognition and recurrent driving mishaps in T1D. Int J Diabetes Mellit. 2010;2:73-77. PMID 21127720 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Berhan Y, et al. Thirty years of nationwide childhood type 1 diabetes incidence in Sweden. Diabetes. 2011;60:577-581. PMID 21270269 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md
Yeung WC, et al. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis. BMJ. 2011;342:d35. PMID 21292721 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
de Boer IH, et al. Long-term renal outcomes after microalbuminuria in DCCT/EDIC. Arch Intern Med. 2011;171:412-420. PMID 21403038 — tags: [2026-deepening] — cited by: complications.md
Yu L, et al. Rituximab selectively suppresses specific islet antibodies. Diabetes. 2011;60:2560-2565. PMID 21831969 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
Simpson M, et al. No association of vitamin D intake or 25-hydroxyvitamin D levels with islet autoimmunity and type 1 diabetes. Diabetologia. 2011;54:2779-2788. PMID 21858504 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Barton FB, et al. Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care. 2012;35:1436-1445. PMID 22723582 — tags: [2026-deepening] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md
Takita M, et al. Adverse events in clinical islet transplantation. Cell Transplant. 2012;21:547-551. PMID 22793063 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Shapiro AM. Islet transplantation in type 1 diabetes: long-term outcome. Rev Diabet Stud. 2012;9:385-406. PMID 23804275 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Fisher MM, et al. Detection of islet β-cell death in vivo by multiplex PCR of differentially methylated DNA. Endocrinology. 2013;154:3476-3481. PMID 23825129 — tags: [2026-deepening] — cited by: biomarkers.md
Frederiksen BN, et al. Vitamin D metabolism gene polymorphisms, islet autoimmunity, and T1D progression. J Clin Endocrinol Metab. 2013;98:E1845-E1851. PMID 23979957 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Shun CB, et al. Thyroid autoimmunity in Type 1 diabetes: systematic review and meta-analysis. Diabet Med. 2014;31:126-135. PMID 24103027 — tags: [2026-deepening] — cited by: complications.md
Leelarathna L, et al. Restoration of self-awareness of hypoglycemia: HypoCOMPaSS clamp substudy. Diabetes Care. 2013;36:4063-4070. PMID 24130355 — tags: [2026-deepening] — cited by: hypoglycemia.md
Little SA, et al. Recovery of hypoglycemia awareness: HypoCOMPaSS randomized trial. Diabetes Care. 2014;37:2114-2122. PMID 24854041 — tags: [2026-deepening] — cited by: hypoglycemia.md
de Boer IH, et al. Renal outcomes in patients with type 1 diabetes and macroalbuminuria. J Am Soc Nephrol. 2014;25:2342-2350. PMID 24925722 — tags: [2026-deepening] — cited by: complications.md
In't Veld P. Insulitis in human type 1 diabetes: a comparison between patients and animal models. Semin Immunopathol. 2014;36:569-579. PMID 25005747 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Bruni A, et al. Islet cell transplantation: recent advances and future challenges. Diabetes Metab Syndr Obes. 2014;7:211-223. PMID 25018643 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Willi SM, et al. Racial-ethnic disparities in management and outcomes among children with type 1 diabetes. Pediatrics. 2015;135:424-434. PMID 25687140 — tags: [2026-deepening] — cited by: complications.md, epidemiology-and-burden.md, overview.md
Giannopoulou EZ, et al. Islet autoantibody phenotypes and incidence in children at increased risk. Diabetologia. 2015;58:2317-2323. PMID 26138334 — tags: [2026-deepening] — cited by: biomarkers.md
Uusitalo U, et al. Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study. JAMA Pediatr. 2016;170:20-28. PMID 26552054 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Soni A, et al. Management of children with T1D during illness: national survey. Postgrad Med J. 2016;92:447-449. PMID 26903663 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Peters AL, et al. DKA with canagliflozin in patients with T1D. Diabetes Care. 2016;39:532-538. PMID 26989182 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Ehlers MR. Strategies for clinical trials in type 1 diabetes. J Autoimmun. 2016;71:88-96. PMID 27068279 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
Pinckney A, et al. Hypoglycemia, variability, and C-Peptide after alefacept in T1DAL. Clin Ther. 2016;38:1327-1339. PMID 27209482 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
Gibb FW, et al. Risk of death following admission with diabetic ketoacidosis. Diabetologia. 2016;59:2082-2087. PMID 27397023 — tags: [2026-deepening] — cited by: complications.md, red-flags-and-safety-concerns.md
Mirmira RG, et al. Biomarkers of β-Cell Stress and Death in Type 1 Diabetes. Curr Diab Rep. 2016;16:95. PMID 27541297 — tags: [2026-deepening] — cited by: biomarkers.md, disease-modifying-immunotherapy.md
Reutrakul S, et al. Sleep characteristics in T1D: systematic review and meta-analysis. Sleep Med. 2016. PMID 27692274 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Hendrieckx C, et al. Severe hypoglycemia, impaired awareness, and self-monitoring in adults. J Diabetes Complications. 2017;31:577-582. PMID 27993524 — tags: [2026-deepening] — cited by: hypoglycemia.md
Frohnert BI, et al. Late-onset islet autoimmunity in childhood: DAISY. Diabetologia. 2017;60:998-1006. PMID 28314946 — tags: [2026-deepening] — cited by: screening-and-early-detection.md, staging-and-natural-history.md
Bone RN, Evans-Molina C. Combination Immunotherapy for Type 1 Diabetes. Curr Diab Rep. 2017;17:50. PMID 28534310 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
McNeilly AD, McCrimmon RJ. Impaired hypoglycaemia awareness in type 1 diabetes: lessons from the lab. Diabetologia. 2018;61:743-750. PMID 29417183 — tags: [2026-deepening] — cited by: hypoglycemia.md
Little SA, et al. Sustained Reduction in Severe Hypoglycemia: Two-Year HypoCOMPaSS Follow-up. Diabetes Care. 2018;41:1600-1607. PMID 29661916 — tags: [2026-deepening] — cited by: hypoglycemia.md
Lablanche S, et al. Islet transplantation versus insulin therapy: TRIMECO randomized trial. Lancet Diabetes Endocrinol. 2018;6:527-537. PMID 29776895 — tags: [2026-deepening] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md
Kuppermann N, et al. Clinical trial of fluid infusion rates for pediatric DKA. N Engl J Med. 2018;378:2275-2287. PMID 29897851 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Linsley PS, et al. Elevated T cell levels predict poor response following rituximab. Genes Immun. 2019;20:293-307. PMID 29925930 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
Farrington C, et al. Women's Experiences of Day-and-Night Closed-Loop Insulin Delivery During Type 1 Diabetes Pregnancy. J Diabetes Sci Technol. 2018;12:1125-1131. PMID 30288999 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md
Senior PA, Pettus JH. Stem cell therapies for Type 1 diabetes: roadmap for clinical trials. Diabet Med. 2019;36:297-307. PMID 30362170 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Nederstigt C, et al. Associated auto-immune disease in type 1 diabetes: systematic review and meta-analysis. Eur J Endocrinol. 2019;180:135-144. PMID 30508413 — tags: [2026-deepening] — cited by: complications.md
Perdigoto AL, et al. Treatment of type 1 diabetes with teplizumab: follow-up after 7 years. Diabetologia. 2019;62:655-664. PMID 30569273 — tags: [2026-deepening] — cited by: biomarkers.md, clinical-trials-landscape.md, disease-modifying-immunotherapy.md
Muñoz-Velandia O, et al. Patient values and preferences regarding pumps and artificial pancreas. Diabetes Technol Ther. 2019;21:183-200. PMID 30839227 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md
Musso G, et al. Sotagliflozin in T1D: meta-analysis of randomized trials. BMJ. 2019;365:l1328. PMID 30967375 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Haller MJ, et al. Low-Dose ATG: Two-Year Clinical Trial Data. Diabetes. 2019;68:1267-1276. PMID 30967424 — tags: [2026-deepening] — cited by: clinical-trials-landscape.md, disease-modifying-immunotherapy.md
Lu J, et al. SGLT inhibitors added to insulin in T1D: meta-analysis of RCTs. Diabetes Metab Res Rev. 2019;35:e3169. PMID 30974510 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Purcell AW, et al. The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes. Diabetes. 2019;68:879-886. PMID 31010879 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Zaharieva DP, et al. CGM Lag Time During Aerobic Exercise in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2019;21:313-321. PMID 31059282 — tags: [2026-deepening] — cited by: hypoglycemia.md, insulin-therapy-and-technology.md
Peters L, et al. Islet-immune interactions in type 1 diabetes: the nexus of beta-cell destruction. Clin Exp Immunol. 2019;198:326-340. PMID 31309537 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Flatt AJS, et al. Predictors of Recurrent Severe Hypoglycemia During HypoCOMPaSS. Diabetes Care. 2020;43:44-52. PMID 31484666 — tags: [2026-deepening] — cited by: hypoglycemia.md
Vantyghem MC, et al. Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation. Diabetes Care. 2019;42:2042-2049. PMID 31615852 — tags: [2026-deepening] — cited by: beta-cell-replacement.md, clinical-trials-landscape.md
Monnier L, et al. Glycemic variability and mean glucose as predictors of hypoglycemia. Diabetes Care. 2020;43:821-827. PMID 31988062 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Pozzilli P, et al. Albiglutide Versus Placebo in Newly Diagnosed Type 1 Diabetes. J Clin Endocrinol Metab. 2020;105. PMID 32219329 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
McQueen RB, et al. Cost and Cost-effectiveness of Large-scale Screening for Type 1 Diabetes in Colorado. Diabetes Care. 2020;43:1496-1503. PMID 32327420 — tags: [2026-deepening] — cited by: screening-and-early-detection.md
Harrison JW, et al. Type 1 diabetes genetic risk score is discriminative of diabetes in non-Europeans. Sci Rep. 2020;10:9450. PMID 32528078 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md, overview.md
Winkley K, et al. Psychological interventions to improve self-management of diabetes. Health Technol Assess. 2020;24:1-232. PMID 32568666 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Liew AY, et al. Pre-transplant psychosocial burden in an integrated national islet transplant program. Islets. 2020;12:21-31. PMID 32815765 — tags: [2026-deepening] — cited by: beta-cell-replacement.md, patient-experience-and-advocacy.md
Moser O, et al. CGM-based glucose management for exercise in T1D. Diabetologia. 2020;63:2501-2520. PMID 33047169 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Faulkner CL, et al. The virome in early life and childhood and development of islet autoimmunity and type 1 diabetes. Rev Med Virol. 2021;31:1-14. PMID 33378601 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Gubitosi-Klug RA, et al. Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia. J Clin Invest. 2021;131. PMID 33529168 — tags: [2026-deepening] — cited by: biomarkers.md, clinical-trials-landscape.md, complications.md, disease-modifying-immunotherapy.md, hypoglycemia.md, red-flags-and-safety-concerns.md
Warren M, et al. Improved postprandial glucose control with ultra rapid lispro versus lispro in pump therapy. Diabetes Obes Metab. 2021;23:1552-1561. PMID 33687783 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md
de Klerk E, Hebrok M. Stem Cell-Based Clinical Trials for Diabetes Mellitus. Front Endocrinol. 2021;12:631463. PMID 33716982 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Chatwin H, et al. The impact of hypoglycaemia on quality of life in adults with type 1 diabetes. Diabetes Res Clin Pract. 2021;174:108752. PMID 33722700 — tags: [2026-deepening] — cited by: hypoglycemia.md
So M, et al. Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies: Beyond a Simple Count. Endocr Rev. 2021;42:584-604. PMID 33881515 — tags: [2026-deepening] — cited by: biomarkers.md
Hall R, et al. Risk factors associated with insulin omission for weight loss in T1D. Clin Child Psychol Psychiatry. 2021;26:606-616. PMID 34121470 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Inns T, et al. Paediatric rotavirus vaccination, coeliac disease and type 1 diabetes in children. BMC Med. 2021;19:147. PMID 34183004 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Krischer JP, et al. Characteristics of children diagnosed with type 1 diabetes before vs after 6 years of age in the TEDDY cohort study. Diabetologia. 2021;64:2247-2257. PMID 34291312 — tags: [2026-deepening] — cited by: overview.md
Harjutsalo V, et al. Long-term population-based trends in cardiovascular disease in type 1 diabetes. Lancet Diabetes Endocrinol. 2021;9:575-585. PMID 34303414 — tags: [2026-deepening] — cited by: complications.md, epidemiology-and-burden.md
Beran M, et al. The bidirectional longitudinal association between depressive symptoms and HbA1c: a systematic review and meta-analysis. Diabet Med. 2022;39:e14671. PMID 34407250 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Abraham MB, et al. Hybrid closed loop and glycemic and psychosocial outcomes in youth. JAMA Pediatr. 2021;175:1227-1235. PMID 34633418 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Leslie RD, et al. Adult-Onset Type 1 Diabetes: Current Understanding and Challenges. Diabetes Care. 2021;44:2449-2456. PMID 34670785 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md, overview.md
Ng K, et al. Islet Autoantibody Type-Specific Titer Thresholds Improve Risk Stratification. Diabetes Care. 2022;45:160-168. PMID 34758977 — tags: [2026-deepening] — cited by: biomarkers.md, screening-and-early-detection.md, staging-and-natural-history.md
Manuwald U, et al. Trends in incidence and prevalence of type 1 diabetes in Saxony. PLoS One. 2021;16:e0262171. PMID 34972197 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md
Boyko EJ, et al. Risk of Foot Ulcer and Lower-Extremity Amputation in DCCT/EDIC. Diabetes Care. 2022;45:357-364. PMID 35007329 — tags: [2026-deepening] — cited by: complications.md
Shapiro AMJ, et al. Insulin expression and C-peptide after stem-cell-derived pancreatic endoderm implantation. Cell Rep Med. 2021;2:100466. PMID 35028608 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Jacobsen LM, et al. Heterogeneity of DKA Incidence in Children Diagnosed in TEDDY. Diabetes Care. 2022;45:624-633. PMID 35043162 — tags: [2026-deepening] — cited by: screening-and-early-detection.md, staging-and-natural-history.md
Teo E, et al. Effectiveness of continuous glucose monitoring in type 1 diabetes. Diabetologia. 2022;65:604-619. PMID 35141761 — tags: [2026-deepening] — cited by: clinical-trials-landscape.md, insulin-therapy-and-technology.md
Fasolino M, et al. Single-cell multi-omics analysis of human pancreatic islets in type 1 diabetes. Nat Metab. 2022;4:284-299. PMID 35228745 — tags: [2026-deepening] — cited by: beta-cell-replacement.md, immunopathogenesis.md
Oram RA, et al. Utility of Diabetes Type-Specific Genetic Risk Scores for Classification Among Multiethnic Youth. Diabetes Care. 2022;45:1124-1131. PMID 35312757 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Harding JL, et al. The Incidence of Adult-Onset Type 1 Diabetes: A Systematic Review From 32 Countries and Regions. Diabetes Care. 2022;45:994-1006. PMID 35349653 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md
Efthymiadis A, et al. The effectiveness of psychological interventions on mental health and quality of life in people living with type 1 diabetes: a systematic review and meta-analysis. Diabetol Int. 2022;13:513-521. PMID 35693990 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Laine AP, et al. Non-HLA polymorphisms in T1D: phase- and endotype-specific effects. Front Immunol. 2022;13:909020. PMID 35812428 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Dhanasekaran M, et al. DKA in pregnancy: risk factors, presentation, and outcomes. J Clin Endocrinol Metab. 2022;107:3137-3143. PMID 35917830 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Choudhary P, et al. Advanced hybrid closed loop versus conventional treatment in adults with type 1 diabetes. Lancet Diabetes Endocrinol. 2022;10:720-731. PMID 36058207 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md
Krischer JP, et al. Predictors of the Initiation of Islet Autoimmunity and Progression. Diabetes Care. 2022;45:2271-2281. PMID 36150053 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md, screening-and-early-detection.md, staging-and-natural-history.md
Sims EK, et al. Persistence of β-Cell Responsiveness for Over Two Years in Autoantibody-Positive Children. Diabetes Care. 2022;45:2982-2990. PMID 36326757 — tags: [2026-deepening] — cited by: biomarkers.md
Annan SF, et al. ISPAD 2022: Nutritional management in children and adolescents. Pediatr Diabetes. 2022;23:1297-1321. PMID 36468223 — tags: [2026-deepening] — cited by: guidelines.md
Deeb A, et al. ISPAD 2022: Ramadan and other religious fasting by young people with diabetes. Pediatr Diabetes. 2022;23:1512-1528. PMID 36537522 — tags: [2026-deepening] — cited by: guidelines.md
Tauschmann M, et al. ISPAD 2022: Diabetes technologies: Glucose monitoring. Pediatr Diabetes. 2022;23:1390-1405. PMID 36537528 — tags: [2026-deepening] — cited by: guidelines.md
Cengiz E, et al. ISPAD 2022: Insulin treatment in children and adolescents. Pediatr Diabetes. 2022;23:1277-1296. PMID 36537533 — tags: [2026-deepening] — cited by: guidelines.md
Ghalwash M, et al. Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes. Lancet Child Adolesc Health. 2023;7:261-268. PMID 36681087 — tags: [2026-deepening] — cited by: screening-and-early-detection.md, staging-and-natural-history.md
Wadwa RP, et al. Trial of Hybrid Closed-Loop Control in Young Children. N Engl J Med. 2023;388:991-1001. PMID 36920756 — tags: [2026-deepening] — cited by: clinical-trials-landscape.md, insulin-therapy-and-technology.md
Thewjitcharoen Y, et al. Misdiagnosed adult-onset T1D identified by C-peptide testing. Heliyon. 2023;9:e14262. PMID 36923852 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Santos SS, et al. Increased risk of death following recurrent ketoacidosis admissions. Diabetol Metab Syndr. 2023;15:85. PMID 37106409 — tags: [2026-deepening] — cited by: complications.md, red-flags-and-safety-concerns.md
Hogrebe NJ, et al. Developments in stem cell-derived islet replacement therapy. Cell Stem Cell. 2023;30:530-548. PMID 37146579 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Lok CW, et al. Diabetes eating problem screening and prevalence in Chinese T1D. BMC Psychiatry. 2023;23:382. PMID 37259043 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Wisel SA, et al. Calcineurin-Sparing Islet and Pancreas Transplantation. Transpl Int. 2023;36:11367. PMID 37359825 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Luckett AM, et al. Utility of genetic risk scores in type 1 diabetes. Diabetologia. 2023;66:1589-1600. PMID 37439792 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Ylescupidez A, et al. OGTT Metrics Surpass CGM Data for T1D Prediction in Multiple-Autoantibody-Positive Individuals. J Clin Endocrinol Metab. 2024;109:57-67. PMID 37572381 — tags: [2026-deepening] — cited by: biomarkers.md
Talbo MK, et al. Effect of diabetes technologies on fear of hypoglycaemia. EClinicalMedicine. 2023;62:102119. PMID 37593226 — tags: [2026-deepening] — cited by: hypoglycemia.md
O'Donnell HK, et al. Anxiety and Risk Perception in Parents of Children Identified by Population Screening as High Risk for Type 1 Diabetes. Diabetes Care. 2023;46:2155-2161. PMID 37673098 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md, screening-and-early-detection.md
Godoi A, et al. Glucose control and psychosocial outcomes with automated insulin delivery for 12 to 96 weeks. Diabetol Metab Syndr. 2023;15:190. PMID 37759290 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md
Lee TTM, et al. Automated insulin delivery in pregnancy complicated by T1D. N Engl J Med. 2023;389:1566-1578. PMID 37796241 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Xie S, et al. Health state utility values for children and adolescents with type 1 diabetes. Diabet Med. 2024;41:e15251. PMID 37915225 — tags: [2026-deepening] — cited by: complications.md, epidemiology-and-burden.md
Aiello EM, et al. Ketone-based alert system for insulin-pump failures. J Diabetes Sci Technol. 2025;19:683-691. PMID 37946403 — tags: [2026-deepening] — cited by: red-flags-and-safety-concerns.md
Singh M, et al. Autoimmune diseases and adverse pregnancy outcomes: an umbrella review. Lancet. 2023;402 Suppl 1:S84. PMID 37997130 — tags: [2026-deepening] — cited by: complications.md
Schipp J, et al. Psychosocial Outcomes Among Users and Nonusers of Open-Source Automated Insulin Delivery Systems. J Med Internet Res. 2023;25:e44002. PMID 38096018 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Knebel UE, et al. Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes. Cell Metab. 2024;36:48-61.e6. PMID 38128529 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Mattila M, et al. Fruit, berry, and vegetable consumption and risk of islet autoimmunity and T1D. Am J Clin Nutr. 2024;119:537-545. PMID 38142920 — tags: [2026-deepening] — cited by: genetics-and-environmental-triggers.md
Núñez-Baila MÁ, et al. Lifestyle in emerging adults with T1D: qualitative systematic review. Healthcare (Basel). 2024;12. PMID 38338194 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Guo M, et al. SIGLEC-1-positive interferon-signature monocytes in recent-onset T1D. Diabetologia. 2024;67:623-640. PMID 38349399 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Coomans de Brachène A, et al. Interferons are key cytokines acting on pancreatic islets in type 1 diabetes. Diabetologia. 2024;67:908-927. PMID 38409439 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Honardoost MA, et al. Immune dysregulation and molecular subtypes revealed by single-cell RNA-seq in T1D. Genome Med. 2024;16:45. PMID 38539228 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Howard KR, et al. Parent, child, and adolescent lived experience using the insulin-only iLet Bionic Pancreas. J Pediatr Psychol. 2024;49:413-420. PMID 38591792 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md
Montaser E, et al. Novel Detection and Progression Markers for Diabetes Based on CGM Data Dynamics. J Clin Endocrinol Metab. 2025;110:254-262. PMID 38820084 — tags: [2026-deepening] — cited by: biomarkers.md
Aanstoot HJ, et al. Cohort profile: Biomarkers of heterogeneity in type 1 diabetes. BMJ Open. 2024;14:e082453. PMID 38904129 — tags: [2026-deepening] — cited by: biomarkers.md
Bell MJ, Neff OT. Exploring the intersection of income and race in people with Type 1 diabetes. Sociol Health Illn. 2024;46:1792-1807. PMID 38965795 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md
Yi-Frazier JP, et al. Promoting resilience in adolescents with T1D: randomized clinical trial. JAMA Netw Open. 2024;7:e2428287. PMID 39158914 — tags: [2026-deepening] — cited by: psychosocial-and-behavioral.md
Garza KP, et al. Adult's Lived Experience Using the Insulin-Only Bionic Pancreas. J Diabetes Sci Technol. 2025;19:11-17. PMID 39212346 — tags: [2026-deepening] — cited by: clinical-trials-landscape.md, patient-experience-and-advocacy.md
Tomic D, et al. The epidemiology of type 1 diabetes mellitus in older adults. Nat Rev Endocrinol. 2025;21:92-104. PMID 39448829 — tags: [2026-deepening] — cited by: epidemiology-and-burden.md
Lin YK, et al. Characterising impaired awareness and associated risks through HypoA-Q. Diabetologia. 2025;68:433-443. PMID 39477881 — tags: [2026-deepening] — cited by: hypoglycemia.md
Galderisi A, et al. Trajectory of beta cell function and insulin clearance in stage 2 type 1 diabetes. Diabetologia. 2025;68:646-661. PMID 39560746 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md, staging-and-natural-history.md
Carré A, et al. Interferon-α promotes HLA-B-restricted presentation of antigens in human pancreatic β-cells. Nat Commun. 2025;16:765. PMID 39824805 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Tauschmann M, et al. ISPAD 2024 Diabetes Technologies: Glucose Monitoring. Horm Res Paediatr. 2024;97:615-635. PMID 39884260 — tags: [2026-deepening] — cited by: guidelines.md
Howard V, et al. Nocturnal caregiving for juveniles with T1D. Psychol Health Med. 2025;30:1701-1722. PMID 40009726 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Sims EK, et al. IA-2A positivity increases risk of progression within and across established stages of type 1 diabetes. Diabetologia. 2025;68:993-1004. PMID 40016443 — tags: [2026-deepening] — cited by: overview.md, screening-and-early-detection.md, staging-and-natural-history.md
van Tienhoven R, et al. Genetic protection from type 1 diabetes resulting from accelerated insulin mRNA decay. Cell. 2025;188:2407-2416.e9. PMID 40112799 — tags: [2026-deepening] — cited by: immunopathogenesis.md
Zafra-Tanaka JH, et al. Patient relevant outcomes for type 1 diabetes management: a qualitative evidence synthesis. Diabet Med. 2025;42:e70016. PMID 40114395 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md
Hering BJ, et al. Advances in Cell Replacement Therapies for Diabetes. Diabetes. 2025;74:1068-1077. PMID 40272266 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
So M, et al. β-Cell Function Derived From Routine Measures Predicts Immunotherapy Response. Diabetes Care. 2025;48:1370-1376. PMID 40424079 — tags: [2026-deepening] — cited by: clinical-trials-landscape.md, disease-modifying-immunotherapy.md
Martinenghi S, et al. Prevention of diabetic ketoacidosis in relatives screened and followed in TrialNet. Diabetologia. 2025;68:1889-1898. PMID 40439773 — tags: [2026-deepening] — cited by: screening-and-early-detection.md, staging-and-natural-history.md
Wang R, et al. Stigma experienced by adolescents with T1D: systematic review and meta-synthesis. Diabet Med. 2025;42:e70088. PMID 40515441 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md, psychosocial-and-behavioral.md
Rewers M. Health economic considerations of screening for early type 1 diabetes. Diabetes Obes Metab. 2025;27 Suppl 6:69-77. PMID 40555704 — tags: [2026-deepening] — cited by: screening-and-early-detection.md
Thabit H, et al. Fully closed-loop control with ultra-rapid versus standard insulin lispro. Diabet Med. 2025;42:e70122. PMID 40815068 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md
Ades R, et al. What does qualitative evidence tell us about how having a diagnosis of type 1 diabetes mellitus impacts an individual's identity? J Health Psychol. 2026;31:983-1000. PMID 40875389 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md
de Visser HS, et al. Automated Insulin Delivery Systems in Children and Adolescents: systematic review and meta-analysis. JAMA Pediatr. 2025;179:1162-1171. PMID 40920375 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md
Donovan LE, et al. Closed-Loop Insulin Delivery in Type 1 Diabetes in Pregnancy. JAMA. 2025;334:2176-2185. PMID 41134589 — tags: [2026-deepening] — cited by: complications.md, insulin-therapy-and-technology.md, red-flags-and-safety-concerns.md
Kuusela S, et al. Islet autoimmunity and progression to type 1 diabetes in the Finnish DIPP study. Diabetologia. 2026;69:93-102. PMID 41204978 — tags: [2026-deepening] — cited by: staging-and-natural-history.md
Galderisi A, et al. Baseline Insulin Secretion Determines Response to Abatacept in Stage 1 Type 1 Diabetes. Diabetes. 2026;75:229-240. PMID 41237315 — tags: [2026-deepening] — cited by: biomarkers.md, clinical-trials-landscape.md, disease-modifying-immunotherapy.md
Biswas S, et al. Immunomodulatory interventions in type 1 diabetes: systematic review and meta-analysis. BMC Endocr Disord. 2025;25:270. PMID 41267047 — tags: [2026-deepening] — cited by: disease-modifying-immunotherapy.md
Chen W, et al. Economic evaluation of potential national childhood screening strategies for type 1 diabetes in Australia. Lancet Reg Health West Pac. 2025;65:101755. PMID 41362419 — tags: [2026-deepening] — cited by: screening-and-early-detection.md
Sebastian-Valles F, et al. Connected smart pen cap in adults with type 1 diabetes: randomized trial. Diabetologia. 2026;69:1191-1204. PMID 41634174 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md
Sherr JL, et al. Persistent Burden of Severe Hypoglycemia and Impaired Awareness Despite Technology Use. Diabetes Care. 2026;49:650-657. PMID 41747141 — tags: [2026-deepening] — cited by: hypoglycemia.md
Sklar J, et al. Barriers to type 1 diabetes medication access and social media support. Diabet Med. 2026;43:e70313. PMID 41996632 — tags: [2026-deepening] — cited by: insulin-therapy-and-technology.md, patient-experience-and-advocacy.md
Templeman EL, et al. Accounting for Age-Related Increases in HbA1c Quantifies Progression Risk in Adults. Diabetes Care. 2026;49:1262-1269. PMID 42090204 — tags: [2026-deepening] — cited by: screening-and-early-detection.md, staging-and-natural-history.md
Delaney PWJ, et al. Reduced Prevalence of Impaired Awareness Over Two Decades in Youth. Diabetes Care. 2026;49:1280-1284. PMID 42138725 — tags: [2026-deepening] — cited by: hypoglycemia.md
Everett EM, et al. Contemporary Diabetes Technology and the Patient Experience. JAMA Netw Open. 2026;9:e2624260. PMID 42479430 — tags: [2026-deepening] — cited by: patient-experience-and-advocacy.md
Chauhan R, et al. Epidemiological and clinical insights from Type 1 Diabetes Global Registries. Diabetes Metab Syndr. 2026;20:103455. PMID 42551241 — tags: [2026-deepening] — cited by: complications.md, epidemiology-and-burden.md, overview.md
Piñar-Gutiérrez A, et al. Natural History of Mild Non-Proliferative Retinopathy Under Contemporary Care. Diabetes Technol Ther. 2026. PMID 42626886 — tags: [2026-deepening] — cited by: complications.md
Hassanein A, et al. Gene-edited hypoimmune islets as a cure for type 1 diabetes. Expert Opin Biol Ther. 2026. PMID 42626948 — tags: [2026-deepening] — cited by: beta-cell-replacement.md
Bellini MI, et al. Simultaneous Pancreas-Kidney Versus Kidney Transplantation Alone. Med Sci (Basel). 2026;14. PMID 42646588 — tags: [2026-deepening] — cited by: beta-cell-replacement.md