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"COMPLETED", "last_update": { "date": "2025-03-07", "type": "ACTUAL" }, "primary_completion": { "date": "2014-02", "type": "ACTUAL" }, "completion": { "date": "2014-02", "type": "ACTUAL" }, "results": true, "results_posted": { "date": "2015-04-01", "type": "ESTIMATED" }, "enrollment": { "count": 608, "type": "ACTUAL" } }, { "id": "NCT00485368", "title": "Angiotensin Converting Enzyme Inhibitors in Marfan Syndrome", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2007-06-13", "type": "ESTIMATED" }, "primary_completion": null, "completion": { "date": "2006-09", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 17, "type": "ACTUAL" } }, { "id": "NCT00538967", "title": "The Effect of Doxycycline on Matrix Metalloproteinase Expression and Activity in the Abdominal Aneurysm", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2007-10-03", "type": "ESTIMATED" }, "primary_completion": null, "completion": { "date": "2005-08", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 60, "type": "ACTUAL" } }, { "id": "NCT00593710", "title": "Losartan Versus Atenolol for the Treatment of Marfan Syndrome", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2012-07-12", "type": "ESTIMATED" }, "primary_completion": { "date": "2010-10", "type": "ACTUAL" }, "completion": { "date": "2011-12", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 17, "type": "ACTUAL" } }, { "id": "NCT00683124", "title": "Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients", "acronym": "MaNeLo", "status": "UNKNOWN", "last_update": { "date": "2011-07-22", "type": "ESTIMATED" }, "primary_completion": { "date": "2013-07", "type": "ESTIMATED" }, "completion": { "date": "2013-07", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 291, "type": "ESTIMATED" } }, { "id": "NCT00723801", "title": "Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2014-09-09", "type": "ESTIMATED" }, "primary_completion": { "date": "2012-12", "type": "ACTUAL" }, "completion": { "date": "2012-12", "type": "ACTUAL" }, "results": true, "results_posted": { "date": "2014-09-01", "type": "ESTIMATED" }, "enrollment": { "count": 40, "type": "ACTUAL" } }, { "id": "NCT00763893", "title": "Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome", "acronym": "MARFANSARTAN", "status": "TERMINATED", "last_update": { "date": "2015-11-04", "type": "ESTIMATED" }, "primary_completion": { "date": "2014-01", "type": "ACTUAL" }, "completion": { "date": "2014-12", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 303, "type": "ACTUAL" } }, { "id": "NCT00782327", "title": "Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2022-12-22", "type": "ACTUAL" }, "primary_completion": { "date": "2014-11-26", "type": "ACTUAL" }, "completion": { "date": "2014-11-26", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 22, "type": "ACTUAL" } }, { "id": "NCT01145612", "title": "Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome", "acronym": "LO-AT-MARFAN01", "status": "UNKNOWN", "last_update": { "date": "2010-08-12", "type": "ESTIMATED" }, "primary_completion": { "date": "2013-02", "type": "ESTIMATED" }, "completion": { "date": "2013-02", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 140, "type": "ACTUAL" } }, { "id": "NCT01295047", "title": "Comparison of Medical Therapies in Marfan Syndrome.", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2011-02-14", "type": "ESTIMATED" }, "primary_completion": { "date": "2007-12", "type": "ACTUAL" }, "completion": { "date": "2008-12", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 18, "type": "ACTUAL" } }, { "id": "NCT01361087", "title": "Circulating Transforming Growth Factor Beta (TGF-\u03b2) in Individuals With Marfan Syndrome", "acronym": null, "status": "WITHDRAWN", "last_update": { "date": "2016-02-05", "type": "ESTIMATED" }, "primary_completion": { "date": "2014-12", "type": "ACTUAL" }, "completion": null, "results": false, "results_posted": null, "enrollment": { "count": 0, "type": "ACTUAL" } }, { "id": "NCT01415804", "title": "Investigation of Stent-grafts in Aortic Dissection (INSTEAD)", "acronym": "INSTEAD", "status": "COMPLETED", "last_update": { "date": "2011-08-12", "type": "ESTIMATED" }, "primary_completion": { "date": "2010-10", "type": "ACTUAL" }, "completion": { "date": "2011-03", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 140, "type": "ACTUAL" } }, { "id": "NCT01715207", "title": "Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2017-06-05", "type": "ACTUAL" }, "primary_completion": { "date": "2014-10", "type": "ACTUAL" }, "completion": { "date": "2014-12", "type": "ACTUAL" }, "results": true, "results_posted": { "date": "2017-05-04", "type": "ACTUAL" }, "enrollment": { "count": 30, "type": "ACTUAL" } }, { "id": "NCT01756833", "title": "Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial", "acronym": "N-TA^3CT", "status": "COMPLETED", "last_update": { "date": "2021-11-26", "type": "ACTUAL" }, "primary_completion": { "date": "2019-07-23", "type": "ACTUAL" }, "completion": { "date": "2019-07-23", "type": "ACTUAL" }, "results": true, "results_posted": { "date": "2021-11-26", "type": "ACTUAL" }, "enrollment": { "count": 261, "type": "ACTUAL" } }, { "id": "NCT01949233", "title": "The Oxford Marfan Trial", "acronym": null, "status": "UNKNOWN", "last_update": { "date": "2015-06-09", "type": "ESTIMATED" }, "primary_completion": { "date": "2015-10", "type": "ESTIMATED" }, "completion": { "date": "2017-12", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 56, "type": "ESTIMATED" } }, { "id": "NCT02086136", "title": "Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection", "acronym": "ADvISED", "status": "COMPLETED", "last_update": { "date": "2019-01-03", "type": "ACTUAL" }, "primary_completion": { "date": "2016-12", "type": "ACTUAL" }, "completion": { "date": "2016-12", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 1900, "type": "ACTUAL" } }, { "id": "NCT02201589", "title": "Feasibility of Endovascular Repair Of Ascending Aortic Pathologies", "acronym": null, "status": "RECRUITING", "last_update": { "date": "2025-05-06", "type": "ACTUAL" }, "primary_completion": { "date": "2028-12", "type": "ESTIMATED" }, "completion": { "date": "2033-12", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 20, "type": "ESTIMATED" } }, { "id": "NCT02256163", "title": "Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm", "acronym": "TAA", "status": "COMPLETED", "last_update": { "date": "2017-11-20", "type": "ACTUAL" }, "primary_completion": { "date": "2016-12", "type": "ACTUAL" }, "completion": { "date": "2017-03", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 258, "type": "ACTUAL" } }, { "id": "NCT02299947", "title": "Bloodtranfusions After Aortic Surgery", "acronym": "FIBTEG", "status": "TERMINATED", "last_update": { "date": "2019-05-10", "type": "ACTUAL" }, "primary_completion": { "date": "2018-04-26", "type": "ACTUAL" }, "completion": { "date": "2018-04-26", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 27, "type": "ACTUAL" } }, { "id": "NCT02538822", "title": "Risk of Rupture of Aneurysms of the Thoracic Ascending Aorta (ATA) From the Dynamic Imaging", "acronym": null, "status": "TERMINATED", "last_update": { "date": "2023-05-24", "type": "ACTUAL" }, "primary_completion": { "date": "2018-09-16", "type": "ACTUAL" }, "completion": { "date": "2018-09-16", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 31, "type": "ACTUAL" } }, { "id": "NCT02724072", "title": "Thoraflex\u2122 Hybrid IDE Study", "acronym": null, "status": "COMPLETED", "last_update": { "date": "2022-05-16", "type": "ACTUAL" }, "primary_completion": { "date": "2019-06-24", "type": "ACTUAL" }, "completion": { "date": "2021-07-30", "type": "ACTUAL" }, "results": false, "results_posted": null, "enrollment": { "count": 84, "type": "ACTUAL" } }, { "id": "NCT02777528", "title": "Evaluation of the GORE\u00ae TBE Device in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta, Zone 0/1", "acronym": "SSB 11-02", "status": "ACTIVE_NOT_RECRUITING", "last_update": { "date": "2026-09-10", "type": "ACTUAL" }, "primary_completion": { "date": "2024-03", "type": "ACTUAL" }, "completion": { "date": "2028-03", "type": "ESTIMATED" }, "results": true, "results_posted": { "date": "2025-06-25", "type": "ACTUAL" }, "enrollment": { "count": 79, "type": "ACTUAL" } }, { "id": "NCT03090763", "title": "Role of Circulating MicroRNAs in Pathogenesis of Aneurysms of the Abdominal and Thoracic Aorta - Study \"Micro AAA\"", "acronym": null, "status": "UNKNOWN", "last_update": { "date": "2017-03-27", "type": "ACTUAL" }, "primary_completion": { "date": "2018-05-01", "type": "ESTIMATED" }, "completion": { "date": "2019-06-01", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 200, "type": "ESTIMATED" } }, { "id": "NCT03142074", "title": "Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms", "acronym": null, "status": "UNKNOWN", "last_update": { "date": "2024-07-01", "type": "ACTUAL" }, "primary_completion": { "date": "2025-12", "type": "ESTIMATED" }, "completion": { "date": "2025-12", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 180, "type": "ESTIMATED" } }, { "id": "NCT03214601", "title": "Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System", "acronym": "RelayBranch", "status": "ACTIVE_NOT_RECRUITING", "last_update": { "date": "2025-05-31", "type": "ACTUAL" }, "primary_completion": { "date": "2023-09-18", "type": "ACTUAL" }, "completion": { "date": "2028-08-31", "type": "ESTIMATED" }, "results": false, "results_posted": null, "enrollment": { "count": 30, "type": "ACTUAL" } }, { "id": "NCT03322033", "title": "Feasibility of Endovascular Repair of Ascending Aortic Pathologies", "acronym": 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