{
 "retrieved_on": "2026-10-14",
 "condition": "thoracic-aortic-aneurysm",
 "author": "Claude Opus 5.5 (sweep author; independent audit pending)",
 "publication_window": {
  "primary": "PubMed Entrez date (edat) 2026/10/07-2026/10/14, plus publication date (pdat) 2026/10/07-2026/10/14",
  "gap_catch_up": "edat 2026/10/01-2026/10/06: previous sweep ended at pdat 2026/09/30 and the requested window began 2026-10-07, so this was run to avoid an unswept gap"
 },
 "pubmed_endpoints": [
  "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi",
  "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi"
 ],
 "searches": {
  "primary_edat:all_thoracic": {
   "parameters": {
    "db": "pubmed",
    "term": "\"aortic aneurysm, thoracic\"[MeSH Terms] OR (thoracic[Title/Abstract] AND aortic[Title/Abstract] AND aneurysm*[Title/Abstract])",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 13,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR (\"thoracic\"[Title/Abstract] AND \"aortic\"[Title/Abstract] AND \"aneurysm*\"[Title/Abstract])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42869089",
    "42865140",
    "42863733",
    "42862301",
    "42861284",
    "42861241",
    "42860936",
    "42859721",
    "42858071",
    "42848775",
    "42842028",
    "42841288",
    "42839658"
   ]
  },
  "primary_edat:epidemiology": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (epidemiology OR incidence OR prevalence OR growth OR natural history OR registry OR burden OR mortality)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 21,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"epidemiologies\"[All Fields] OR \"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"epidemiology s\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields]) OR (\"growth and development\"[MeSH Subheading] OR (\"growth\"[All Fields] AND \"development\"[All Fields]) OR \"growth and development\"[All Fields] OR \"growth\"[All Fields] OR \"growth\"[MeSH Terms] OR \"growths\"[All Fields]) OR (\"natural history\"[MeSH Terms] OR (\"natural\"[All Fields] AND \"history\"[All Fields]) OR \"natural history\"[All Fields]) OR (\"registries\"[MeSH Terms] OR \"registries\"[All Fields] OR \"registry\"[All Fields] OR \"registry s\"[All Fields]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42869089",
    "42864670",
    "42862301",
    "42861363",
    "42861241",
    "42861074",
    "42859704",
    "42859541",
    "42859505",
    "42859403",
    "42858071",
    "42858043",
    "42854033",
    "42854006",
    "42850148",
    "42847578",
    "42842764",
    "42842028",
    "42841288",
    "42840784",
    "42839659"
   ]
  },
  "primary_edat:genetics_syndromes": {
   "parameters": {
    "db": "pubmed",
    "term": "(Marfan OR Loeys-Dietz OR vascular Ehlers-Danlos OR Turner OR (\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract])) AND (aort* AND (genetic* OR heritable OR variant OR syndrome OR screening))",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 21,
   "translated_query": "(\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields] OR \"Loeys-Dietz\"[All Fields] OR ((\"blood vessels\"[MeSH Terms] OR (\"blood\"[All Fields] AND \"vessels\"[All Fields]) OR \"blood vessels\"[All Fields] OR \"vascular\"[All Fields] OR \"vascularisation\"[All Fields] OR \"neovascularization, pathologic\"[MeSH Terms] OR (\"neovascularization\"[All Fields] AND \"pathologic\"[All Fields]) OR \"pathologic neovascularization\"[All Fields] OR \"vascularization\"[All Fields] OR \"vascularisations\"[All Fields] OR \"vascularise\"[All Fields] OR \"vascularised\"[All Fields] OR \"vascularities\"[All Fields] OR \"vascularitis\"[All Fields] OR \"vascularity\"[All Fields] OR \"vascularizations\"[All Fields] OR \"vascularize\"[All Fields] OR \"vascularized\"[All Fields] OR \"vascularizes\"[All Fields] OR \"vascularizing\"[All Fields] OR \"vasculars\"[All Fields]) AND \"Ehlers-Danlos\"[All Fields]) OR (\"turner\"[All Fields] OR \"turner s\"[All Fields] OR \"turners\"[All Fields]) OR (\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract])) AND (\"aort*\"[All Fields] AND (\"genetic*\"[All Fields] OR (\"heritabilities\"[All Fields] OR \"heritability\"[All Fields] OR \"heritable\"[All Fields] OR \"heritably\"[All Fields]) OR (\"variant\"[All Fields] OR \"variant s\"[All Fields] OR \"variants\"[All Fields]) OR (\"syndrom\"[All Fields] OR \"syndromal\"[All Fields] OR \"syndromally\"[All Fields] OR \"syndrome\"[MeSH Terms] OR \"syndrome\"[All Fields] OR \"syndromes\"[All Fields] OR \"syndrome s\"[All Fields] OR \"syndromic\"[All Fields] OR \"syndroms\"[All Fields]) OR (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields]))) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42869089",
    "42864670",
    "42862682",
    "42862301",
    "42862110",
    "42861284",
    "42861142",
    "42861074",
    "42859743",
    "42859505",
    "42857991",
    "42857757",
    "42854033",
    "42850572",
    "42850148",
    "42849511",
    "42848775",
    "42842028",
    "42841288",
    "42840921",
    "42839659"
   ]
  },
  "primary_edat:bicuspid": {
   "parameters": {
    "db": "pubmed",
    "term": "(bicuspid aortic valve) AND (aortopathy OR aneurysm OR dilation OR dilatation)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 5,
   "translated_query": "(\"bicuspid aortic valve disease\"[MeSH Terms] OR (\"bicuspid\"[All Fields] AND \"aortic\"[All Fields] AND \"valve\"[All Fields] AND \"disease\"[All Fields]) OR \"bicuspid aortic valve disease\"[All Fields] OR (\"bicuspid\"[All Fields] AND \"aortic\"[All Fields] AND \"valve\"[All Fields]) OR \"bicuspid aortic valve\"[All Fields]) AND (\"aortopathies\"[All Fields] OR \"aortopathy\"[All Fields] OR (\"aneurysm\"[MeSH Terms] OR \"aneurysm\"[All Fields] OR \"aneurysms\"[All Fields] OR \"aneurysm s\"[All Fields] OR \"aneurysmal\"[All Fields] OR \"aneurysmally\"[All Fields] OR \"aneurysmic\"[All Fields]) OR (\"dilatable\"[All Fields] OR \"dilatated\"[All Fields] OR \"dilatating\"[All Fields] OR \"dilatation\"[MeSH Terms] OR \"dilatation\"[All Fields] OR \"dilatations\"[All Fields] OR \"dilate\"[All Fields] OR \"dilation\"[All Fields] OR \"dilations\"[All Fields] OR \"dilatative\"[All Fields] OR \"dilatator\"[All Fields] OR \"dilatators\"[All Fields] OR \"dilated\"[All Fields] OR \"dilates\"[All Fields] OR \"dilating\"[All Fields] OR \"dilator\"[All Fields] OR \"dilators\"[All Fields]) OR (\"dilatable\"[All Fields] OR \"dilatated\"[All Fields] OR \"dilatating\"[All Fields] OR \"dilatation\"[MeSH Terms] OR \"dilatation\"[All Fields] OR \"dilatations\"[All Fields] OR \"dilate\"[All Fields] OR \"dilation\"[All Fields] OR \"dilations\"[All Fields] OR \"dilatative\"[All Fields] OR \"dilatator\"[All Fields] OR \"dilatators\"[All Fields] OR \"dilated\"[All Fields] OR \"dilates\"[All Fields] OR \"dilating\"[All Fields] OR \"dilator\"[All Fields] OR \"dilators\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42865140",
    "42861241",
    "42861042",
    "42859743",
    "42839658"
   ]
  },
  "primary_edat:mechanisms_models_omics": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (mechanism OR inflammation OR smooth muscle OR extracellular matrix OR TGF OR mouse OR mice OR animal model OR transcriptom* OR proteom* OR single-cell OR GWAS)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 19,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"mechanism\"[All Fields] OR \"mechanisms\"[All Fields] OR (\"inflammation\"[MeSH Terms] OR \"inflammation\"[All Fields] OR \"inflammations\"[All Fields] OR \"inflammation s\"[All Fields]) OR (\"muscle, smooth\"[MeSH Terms] OR (\"muscle\"[All Fields] AND \"smooth\"[All Fields]) OR \"smooth muscle\"[All Fields] OR (\"smooth\"[All Fields] AND \"muscle\"[All Fields])) OR (\"extracellular matrix\"[MeSH Terms] OR (\"extracellular\"[All Fields] AND \"matrix\"[All Fields]) OR \"extracellular matrix\"[All Fields]) OR \"TGF\"[All Fields] OR (\"mice\"[MeSH Terms] OR \"mice\"[All Fields] OR \"mouse\"[All Fields] OR \"mouse s\"[All Fields] OR \"mouses\"[All Fields]) OR (\"mice\"[MeSH Terms] OR \"mice\"[All Fields]) OR (\"models, animal\"[MeSH Terms] OR (\"models\"[All Fields] AND \"animal\"[All Fields]) OR \"animal models\"[All Fields] OR (\"animal\"[All Fields] AND \"model\"[All Fields]) OR \"animal model\"[All Fields]) OR \"transcriptom*\"[All Fields] OR \"proteom*\"[All Fields] OR \"single-cell\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42866932",
    "42865140",
    "42861284",
    "42861241",
    "42860230",
    "42859505",
    "42859403",
    "42858776",
    "42858071",
    "42858043",
    "42857991",
    "42857971",
    "42857389",
    "42853709",
    "42848843",
    "42848775",
    "42842764",
    "42842028",
    "42839658"
   ]
  },
  "primary_edat:imaging_biomechanics": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (imaging OR surveillance OR magnetic resonance OR computed tomography OR echocardiography OR biomechanics OR wall stress OR flow OR measurement)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 31,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"image s\"[All Fields] OR \"imaged\"[All Fields] OR \"imager\"[All Fields] OR \"imager s\"[All Fields] OR \"imagers\"[All Fields] OR \"images\"[All Fields] OR \"imaging\"[All Fields] OR \"imaging s\"[All Fields] OR \"imagings\"[All Fields] OR \"intrauterine growth retardation metaphyseal dysplasia adrenal hypoplasia congenita and genital anomalies\"[Supplementary Concept] OR \"intrauterine growth retardation metaphyseal dysplasia adrenal hypoplasia congenita and genital anomalies\"[All Fields] OR \"image\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"surveillance\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"surveilance\"[All Fields] OR \"surveillances\"[All Fields] OR \"surveilled\"[All Fields] OR \"surveillence\"[All Fields]) OR (\"magnetic resonance spectroscopy\"[MeSH Terms] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields] AND \"spectroscopy\"[All Fields]) OR \"magnetic resonance spectroscopy\"[All Fields] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields]) OR \"magnetic resonance\"[All Fields]) OR (\"tomography, x ray computed\"[MeSH Terms] OR (\"tomography\"[All Fields] AND \"x ray\"[All Fields] AND \"computed\"[All Fields]) OR \"x-ray computed tomography\"[All Fields] OR (\"computed\"[All Fields] AND \"tomography\"[All Fields]) OR \"computed tomography\"[All Fields]) OR (\"echocardiographies\"[All Fields] OR \"echocardiography\"[MeSH Terms] OR \"echocardiography\"[All Fields]) OR (\"biomechanical phenomena\"[MeSH Terms] OR (\"biomechanical\"[All Fields] AND \"phenomena\"[All Fields]) OR \"biomechanical phenomena\"[All Fields] OR \"biomechanic\"[All Fields] OR \"biomechanics\"[All Fields] OR \"biomechanical\"[All Fields] OR \"biomechanically\"[All Fields]) OR (\"wall\"[All Fields] AND (\"stress\"[All Fields] OR \"stressed\"[All Fields] OR \"stresses\"[All Fields] OR \"stressful\"[All Fields] OR \"stressfulness\"[All Fields] OR \"stressing\"[All Fields])) OR (\"flow camb\"[Journal] OR \"flow\"[All Fields]) OR (\"measurability\"[All Fields] OR \"measurable\"[All Fields] OR \"measurably\"[All Fields] OR \"measure s\"[All Fields] OR \"measureable\"[All Fields] OR \"measured\"[All Fields] OR \"measurement\"[All Fields] OR \"measurement s\"[All Fields] OR \"measurements\"[All Fields] OR \"measurer\"[All Fields] OR \"measurers\"[All Fields] OR \"measuring\"[All Fields] OR \"measurings\"[All Fields] OR \"measurment\"[All Fields] OR \"measurments\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"measure\"[All Fields] OR \"measures\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42865140",
    "42862682",
    "42862301",
    "42862110",
    "42861142",
    "42861074",
    "42861042",
    "42860936",
    "42860793",
    "42860230",
    "42859743",
    "42859541",
    "42859505",
    "42859403",
    "42858776",
    "42857757",
    "42857752",
    "42857389",
    "42854006",
    "42853709",
    "42850572",
    "42850148",
    "42849511",
    "42848843",
    "42847576",
    "42842764",
    "42842028",
    "42841288",
    "42840784",
    "42839659",
    "42839658"
   ]
  },
  "primary_edat:risk_biomarkers": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (risk prediction OR risk stratification OR threshold OR diameter OR biomarker OR microRNA)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 15,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (((\"risk\"[MeSH Terms] OR \"risk\"[All Fields]) AND (\"predict\"[All Fields] OR \"predictabilities\"[All Fields] OR \"predictability\"[All Fields] OR \"predictable\"[All Fields] OR \"predictably\"[All Fields] OR \"predicted\"[All Fields] OR \"predicting\"[All Fields] OR \"prediction\"[All Fields] OR \"predictions\"[All Fields] OR \"predictive\"[All Fields] OR \"predictively\"[All Fields] OR \"predictiveness\"[All Fields] OR \"predictives\"[All Fields] OR \"predictivities\"[All Fields] OR \"predictivity\"[All Fields] OR \"predicts\"[All Fields])) OR ((\"risk\"[MeSH Terms] OR \"risk\"[All Fields]) AND (\"stratification\"[All Fields] OR \"stratifications\"[All Fields])) OR (\"threshold\"[All Fields] OR \"thresholds\"[All Fields]) OR (\"diameter\"[All Fields] OR \"diameters\"[All Fields]) OR (\"biomarker s\"[All Fields] OR \"biomarkers\"[Supplementary Concept] OR \"biomarkers\"[All Fields] OR \"biomarker\"[All Fields] OR \"biomarkers\"[MeSH Terms]) OR (\"microrna s\"[All Fields] OR \"micrornas\"[Supplementary Concept] OR \"micrornas\"[All Fields] OR \"microrna\"[All Fields] OR \"micrornas\"[MeSH Terms])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42869089",
    "42868953",
    "42865140",
    "42864670",
    "42861074",
    "42861042",
    "42860793",
    "42859704",
    "42858043",
    "42857971",
    "42854006",
    "42850148",
    "42849511",
    "42848775",
    "42841288"
   ]
  },
  "primary_edat:medical_exercise_safety": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (drug OR therapy OR losartan OR beta-blocker OR angiotensin OR exercise OR pregnancy OR fluoroquinolone)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 16,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"drug\"[All Fields] OR (\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"therapies\"[All Fields] OR \"therapy\"[MeSH Subheading] OR \"therapy\"[All Fields] OR \"therapy s\"[All Fields] OR \"therapys\"[All Fields]) OR (\"losartan\"[Supplementary Concept] OR \"losartan\"[All Fields] OR \"losartan\"[MeSH Terms] OR \"losartan s\"[All Fields] OR \"losartane\"[All Fields]) OR (\"adrenergic beta antagonists\"[Pharmacological Action] OR \"adrenergic beta antagonists\"[Supplementary Concept] OR \"adrenergic beta antagonists\"[All Fields] OR \"beta blocker\"[All Fields] OR \"adrenergic beta antagonists\"[MeSH Terms] OR (\"adrenergic\"[All Fields] AND \"beta antagonists\"[All Fields]) OR (\"beta\"[All Fields] AND \"blocker\"[All Fields])) OR (\"angiotensin s\"[All Fields] OR \"angiotensine\"[All Fields] OR \"angiotensins\"[Supplementary Concept] OR \"angiotensins\"[All Fields] OR \"angiotensin\"[All Fields] OR \"angiotensins\"[MeSH Terms]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"pregnancy\"[MeSH Terms] OR \"pregnancy\"[All Fields] OR \"pregnancies\"[All Fields] OR \"pregnancy s\"[All Fields]) OR (\"fluoroquinolon\"[All Fields] OR \"fluoroquinolones\"[Supplementary Concept] OR \"fluoroquinolones\"[All Fields] OR \"fluoroquinolone\"[All Fields] OR \"fluoroquinolones\"[MeSH Terms] OR \"fluoroquinolonic\"[All Fields] OR \"fluoroquinolons\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42864670",
    "42862682",
    "42862110",
    "42861284",
    "42861142",
    "42860230",
    "42859505",
    "42859403",
    "42858776",
    "42858043",
    "42857757",
    "42857389",
    "42848843",
    "42841288",
    "42840784",
    "42839658"
   ]
  },
  "primary_edat:surgery_devices": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (surgery OR surgical OR endovascular OR TEVAR OR valve-sparing OR stent OR repair)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 37,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"surgery\"[MeSH Subheading] OR \"surgery\"[All Fields] OR \"surgical procedures, operative\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"procedures\"[All Fields] AND \"operative\"[All Fields]) OR \"operative surgical procedures\"[All Fields] OR \"general surgery\"[MeSH Terms] OR (\"general\"[All Fields] AND \"surgery\"[All Fields]) OR \"general surgery\"[All Fields] OR \"surgery s\"[All Fields] OR \"surgerys\"[All Fields] OR \"surgeries\"[All Fields] OR (\"surgical procedures, operative\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"procedures\"[All Fields] AND \"operative\"[All Fields]) OR \"operative surgical procedures\"[All Fields] OR \"surgical\"[All Fields] OR \"surgically\"[All Fields] OR \"surgicals\"[All Fields]) OR \"endovascular\"[All Fields] OR (\"endovascular aneurysm repair\"[MeSH Terms] OR (\"endovascular\"[All Fields] AND \"aneurysm\"[All Fields] AND \"repair\"[All Fields]) OR \"endovascular aneurysm repair\"[All Fields] OR \"tevar\"[All Fields] OR \"tevars\"[All Fields]) OR \"valve-sparing\"[All Fields] OR (\"stent s\"[All Fields] OR \"stentings\"[All Fields] OR \"stents\"[MeSH Terms] OR \"stents\"[All Fields] OR \"stent\"[All Fields] OR \"stented\"[All Fields] OR \"stenting\"[All Fields]) OR (\"repairability\"[All Fields] OR \"repairable\"[All Fields] OR \"repaire\"[All Fields] OR \"repaired\"[All Fields] OR \"repairment\"[All Fields] OR \"wound healing\"[MeSH Terms] OR (\"wound\"[All Fields] AND \"healing\"[All Fields]) OR \"wound healing\"[All Fields] OR \"repair\"[All Fields] OR \"repairing\"[All Fields] OR \"repairs\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42869527",
    "42869089",
    "42868953",
    "42865140",
    "42864670",
    "42862682",
    "42862110",
    "42861363",
    "42861241",
    "42861142",
    "42861074",
    "42860936",
    "42860793",
    "42860230",
    "42859743",
    "42859704",
    "42859541",
    "42859505",
    "42859403",
    "42858043",
    "42857991",
    "42857757",
    "42857752",
    "42857389",
    "42855421",
    "42854006",
    "42849511",
    "42848843",
    "42848775",
    "42847578",
    "42847576",
    "42846901",
    "42841288",
    "42840921",
    "42840784",
    "42839659",
    "42839658"
   ]
  },
  "primary_edat:dissection": {
   "parameters": {
    "db": "pubmed",
    "term": "\"aortic dissection\"[Title/Abstract]",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 31,
   "translated_query": "\"aortic dissection\"[Title/Abstract] AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42869527",
    "42869089",
    "42868953",
    "42866932",
    "42864670",
    "42862110",
    "42861363",
    "42861284",
    "42861241",
    "42861074",
    "42860793",
    "42859704",
    "42859541",
    "42859505",
    "42858071",
    "42858043",
    "42857991",
    "42857971",
    "42857757",
    "42857752",
    "42855421",
    "42854033",
    "42854006",
    "42853709",
    "42850572",
    "42849511",
    "42846901",
    "42842764",
    "42840921",
    "42840784",
    "42839659"
   ]
  },
  "primary_edat:guidelines": {
   "parameters": {
    "db": "pubmed",
    "term": "(aort* OR Marfan OR Loeys-Dietz OR vascular Ehlers-Danlos OR Turner) AND (guideline OR consensus OR scientific statement OR position statement OR Ghent)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 17,
   "translated_query": "(\"aort*\"[All Fields] OR (\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields]) OR \"Loeys-Dietz\"[All Fields] OR ((\"blood vessels\"[MeSH Terms] OR (\"blood\"[All Fields] AND \"vessels\"[All Fields]) OR \"blood vessels\"[All Fields] OR \"vascular\"[All Fields] OR \"vascularisation\"[All Fields] OR \"neovascularization, pathologic\"[MeSH Terms] OR (\"neovascularization\"[All Fields] AND \"pathologic\"[All Fields]) OR \"pathologic neovascularization\"[All Fields] OR \"vascularization\"[All Fields] OR \"vascularisations\"[All Fields] OR \"vascularise\"[All Fields] OR \"vascularised\"[All Fields] OR \"vascularities\"[All Fields] OR \"vascularitis\"[All Fields] OR \"vascularity\"[All Fields] OR \"vascularizations\"[All Fields] OR \"vascularize\"[All Fields] OR \"vascularized\"[All Fields] OR \"vascularizes\"[All Fields] OR \"vascularizing\"[All Fields] OR \"vasculars\"[All Fields]) AND \"Ehlers-Danlos\"[All Fields]) OR (\"turner\"[All Fields] OR \"turner s\"[All Fields] OR \"turners\"[All Fields])) AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]) OR ((\"science\"[MeSH Terms] OR \"science\"[All Fields] OR \"scientific\"[All Fields] OR \"scientifical\"[All Fields] OR \"scientifically\"[All Fields] OR \"scientification\"[All Fields] OR \"scientificity\"[All Fields] OR \"scientifics\"[All Fields]) AND (\"statement\"[All Fields] OR \"statement s\"[All Fields] OR \"statements\"[All Fields])) OR ((\"patient positioning\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"positioning\"[All Fields]) OR \"patient positioning\"[All Fields] OR \"positioning\"[All Fields] OR \"position\"[All Fields] OR \"position s\"[All Fields] OR \"positional\"[All Fields] OR \"positioned\"[All Fields] OR \"positionings\"[All Fields] OR \"positions\"[All Fields]) AND (\"statement\"[All Fields] OR \"statement s\"[All Fields] OR \"statements\"[All Fields])) OR \"Ghent\"[All Fields]) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42866921",
    "42863075",
    "42862939",
    "42862070",
    "42861241",
    "42859523",
    "42859403",
    "42857632",
    "42857389",
    "42856077",
    "42855990",
    "42853682",
    "42843586",
    "42841221",
    "42839659",
    "42839658",
    "42839649"
   ]
  },
  "primary_edat:patient_experience": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (patient reported OR quality of life OR qualitative OR psychosocial OR awareness OR shared decision OR rehabilitation)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 16,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]) OR (\"psychosocial\"[All Fields] OR \"psychosocially\"[All Fields]) OR (\"awareness\"[MeSH Terms] OR \"awareness\"[All Fields] OR \"aware\"[All Fields] OR \"awarenesses\"[All Fields]) OR ((\"share\"[All Fields] OR \"shared\"[All Fields] OR \"shares\"[All Fields] OR \"sharing\"[All Fields] OR \"sharings\"[All Fields]) AND (\"decision\"[All Fields] OR \"decision s\"[All Fields] OR \"decisions\"[All Fields] OR \"decisive\"[All Fields] OR \"decisively\"[All Fields])) OR (\"rehabilitant\"[All Fields] OR \"rehabilitants\"[All Fields] OR \"rehabilitate\"[All Fields] OR \"rehabilitated\"[All Fields] OR \"rehabilitates\"[All Fields] OR \"rehabilitating\"[All Fields] OR \"rehabilitation\"[MeSH Terms] OR \"rehabilitation\"[All Fields] OR \"rehabilitations\"[All Fields] OR \"rehabilitative\"[All Fields] OR \"rehabilitation\"[MeSH Subheading] OR \"rehabilitation s\"[All Fields] OR \"rehabilitational\"[All Fields] OR \"rehabilitator\"[All Fields] OR \"rehabilitators\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42862682",
    "42861363",
    "42859743",
    "42859704",
    "42859541",
    "42859505",
    "42857757",
    "42857752",
    "42857389",
    "42854033",
    "42850572",
    "42847578",
    "42847576",
    "42840921",
    "42839659",
    "42839658"
   ]
  },
  "primary_edat:cochrane": {
   "parameters": {
    "db": "pubmed",
    "term": "\"Cochrane Database Syst Rev\"[jour] AND (aort* OR Marfan OR aneurysm*)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 0,
   "translated_query": "\"Cochrane Database Syst Rev\"[Journal] AND (\"aort*\"[All Fields] OR (\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields]) OR \"aneurysm*\"[All Fields]) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": []
  },
  "primary_edat:systematic_reviews": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract] OR Marfan[Title/Abstract] OR Loeys-Dietz[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (systematic review[pt] OR meta-analysis[pt] OR \"systematic review\"[Title/Abstract] OR \"meta-analysis\"[Title/Abstract])",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 4,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract] OR \"Marfan\"[Title/Abstract] OR \"Loeys-Dietz\"[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (\"systematic review\"[Publication Type] OR \"meta-analysis\"[Publication Type] OR \"systematic review\"[Title/Abstract] OR \"meta-analysis\"[Title/Abstract]) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": [
    "42861241",
    "42852470",
    "42849511",
    "42839658"
   ]
  },
  "primary_edat:trials_pt": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract] OR Marfan[Title/Abstract] OR Loeys-Dietz[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt])",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 0,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract] OR \"Marfan\"[Title/Abstract] OR \"Loeys-Dietz\"[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (\"randomized controlled trial\"[Publication Type] OR \"clinical trial\"[Publication Type]) AND 2026/10/07:2026/10/14[Date - Entry]",
   "pmids": []
  },
  "primary_pdat:all_thoracic": {
   "parameters": {
    "db": "pubmed",
    "term": "\"aortic aneurysm, thoracic\"[MeSH Terms] OR (thoracic[Title/Abstract] AND aortic[Title/Abstract] AND aneurysm*[Title/Abstract])",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 11,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR (\"thoracic\"[Title/Abstract] AND \"aortic\"[Title/Abstract] AND \"aneurysm*\"[Title/Abstract])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42869089",
    "42865140",
    "42863733",
    "42862301",
    "42858071",
    "42848775",
    "42842028",
    "42841288",
    "42839658",
    "42824407",
    "42466795"
   ]
  },
  "primary_pdat:epidemiology": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (epidemiology OR incidence OR prevalence OR growth OR natural history OR registry OR burden OR mortality)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 14,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"epidemiologies\"[All Fields] OR \"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"epidemiology s\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields]) OR (\"growth and development\"[MeSH Subheading] OR (\"growth\"[All Fields] AND \"development\"[All Fields]) OR \"growth and development\"[All Fields] OR \"growth\"[All Fields] OR \"growth\"[MeSH Terms] OR \"growths\"[All Fields]) OR (\"natural history\"[MeSH Terms] OR (\"natural\"[All Fields] AND \"history\"[All Fields]) OR \"natural history\"[All Fields]) OR (\"registries\"[MeSH Terms] OR \"registries\"[All Fields] OR \"registry\"[All Fields] OR \"registry s\"[All Fields]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42869089",
    "42864670",
    "42862301",
    "42859505",
    "42859403",
    "42858071",
    "42858043",
    "42854033",
    "42854006",
    "42847578",
    "42842028",
    "42841288",
    "42839659",
    "40680099"
   ]
  },
  "primary_pdat:genetics_syndromes": {
   "parameters": {
    "db": "pubmed",
    "term": "(Marfan OR Loeys-Dietz OR vascular Ehlers-Danlos OR Turner OR (\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract])) AND (aort* AND (genetic* OR heritable OR variant OR syndrome OR screening))",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 15,
   "translated_query": "(\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields] OR \"Loeys-Dietz\"[All Fields] OR ((\"blood vessels\"[MeSH Terms] OR (\"blood\"[All Fields] AND \"vessels\"[All Fields]) OR \"blood vessels\"[All Fields] OR \"vascular\"[All Fields] OR \"vascularisation\"[All Fields] OR \"neovascularization, pathologic\"[MeSH Terms] OR (\"neovascularization\"[All Fields] AND \"pathologic\"[All Fields]) OR \"pathologic neovascularization\"[All Fields] OR \"vascularization\"[All Fields] OR \"vascularisations\"[All Fields] OR \"vascularise\"[All Fields] OR \"vascularised\"[All Fields] OR \"vascularities\"[All Fields] OR \"vascularitis\"[All Fields] OR \"vascularity\"[All Fields] OR \"vascularizations\"[All Fields] OR \"vascularize\"[All Fields] OR \"vascularized\"[All Fields] OR \"vascularizes\"[All Fields] OR \"vascularizing\"[All Fields] OR \"vasculars\"[All Fields]) AND \"Ehlers-Danlos\"[All Fields]) OR (\"turner\"[All Fields] OR \"turner s\"[All Fields] OR \"turners\"[All Fields]) OR (\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract])) AND (\"aort*\"[All Fields] AND (\"genetic*\"[All Fields] OR (\"heritabilities\"[All Fields] OR \"heritability\"[All Fields] OR \"heritable\"[All Fields] OR \"heritably\"[All Fields]) OR (\"variant\"[All Fields] OR \"variant s\"[All Fields] OR \"variants\"[All Fields]) OR (\"syndrom\"[All Fields] OR \"syndromal\"[All Fields] OR \"syndromally\"[All Fields] OR \"syndrome\"[MeSH Terms] OR \"syndrome\"[All Fields] OR \"syndromes\"[All Fields] OR \"syndrome s\"[All Fields] OR \"syndromic\"[All Fields] OR \"syndroms\"[All Fields]) OR (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields]))) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42869089",
    "42864670",
    "42862301",
    "42862110",
    "42859505",
    "42857991",
    "42854033",
    "42850572",
    "42849511",
    "42848775",
    "42842028",
    "42841288",
    "42839659",
    "42501031",
    "40680099"
   ]
  },
  "primary_pdat:bicuspid": {
   "parameters": {
    "db": "pubmed",
    "term": "(bicuspid aortic valve) AND (aortopathy OR aneurysm OR dilation OR dilatation)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 2,
   "translated_query": "(\"bicuspid aortic valve disease\"[MeSH Terms] OR (\"bicuspid\"[All Fields] AND \"aortic\"[All Fields] AND \"valve\"[All Fields] AND \"disease\"[All Fields]) OR \"bicuspid aortic valve disease\"[All Fields] OR (\"bicuspid\"[All Fields] AND \"aortic\"[All Fields] AND \"valve\"[All Fields]) OR \"bicuspid aortic valve\"[All Fields]) AND (\"aortopathies\"[All Fields] OR \"aortopathy\"[All Fields] OR (\"aneurysm\"[MeSH Terms] OR \"aneurysm\"[All Fields] OR \"aneurysms\"[All Fields] OR \"aneurysm s\"[All Fields] OR \"aneurysmal\"[All Fields] OR \"aneurysmally\"[All Fields] OR \"aneurysmic\"[All Fields]) OR (\"dilatable\"[All Fields] OR \"dilatated\"[All Fields] OR \"dilatating\"[All Fields] OR \"dilatation\"[MeSH Terms] OR \"dilatation\"[All Fields] OR \"dilatations\"[All Fields] OR \"dilate\"[All Fields] OR \"dilation\"[All Fields] OR \"dilations\"[All Fields] OR \"dilatative\"[All Fields] OR \"dilatator\"[All Fields] OR \"dilatators\"[All Fields] OR \"dilated\"[All Fields] OR \"dilates\"[All Fields] OR \"dilating\"[All Fields] OR \"dilator\"[All Fields] OR \"dilators\"[All Fields]) OR (\"dilatable\"[All Fields] OR \"dilatated\"[All Fields] OR \"dilatating\"[All Fields] OR \"dilatation\"[MeSH Terms] OR \"dilatation\"[All Fields] OR \"dilatations\"[All Fields] OR \"dilate\"[All Fields] OR \"dilation\"[All Fields] OR \"dilations\"[All Fields] OR \"dilatative\"[All Fields] OR \"dilatator\"[All Fields] OR \"dilatators\"[All Fields] OR \"dilated\"[All Fields] OR \"dilates\"[All Fields] OR \"dilating\"[All Fields] OR \"dilator\"[All Fields] OR \"dilators\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42865140",
    "42839658"
   ]
  },
  "primary_pdat:mechanisms_models_omics": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (mechanism OR inflammation OR smooth muscle OR extracellular matrix OR TGF OR mouse OR mice OR animal model OR transcriptom* OR proteom* OR single-cell OR GWAS)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 16,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"mechanism\"[All Fields] OR \"mechanisms\"[All Fields] OR (\"inflammation\"[MeSH Terms] OR \"inflammation\"[All Fields] OR \"inflammations\"[All Fields] OR \"inflammation s\"[All Fields]) OR (\"muscle, smooth\"[MeSH Terms] OR (\"muscle\"[All Fields] AND \"smooth\"[All Fields]) OR \"smooth muscle\"[All Fields] OR (\"smooth\"[All Fields] AND \"muscle\"[All Fields])) OR (\"extracellular matrix\"[MeSH Terms] OR (\"extracellular\"[All Fields] AND \"matrix\"[All Fields]) OR \"extracellular matrix\"[All Fields]) OR \"TGF\"[All Fields] OR (\"mice\"[MeSH Terms] OR \"mice\"[All Fields] OR \"mouse\"[All Fields] OR \"mouse s\"[All Fields] OR \"mouses\"[All Fields]) OR (\"mice\"[MeSH Terms] OR \"mice\"[All Fields]) OR (\"models, animal\"[MeSH Terms] OR (\"models\"[All Fields] AND \"animal\"[All Fields]) OR \"animal models\"[All Fields] OR (\"animal\"[All Fields] AND \"model\"[All Fields]) OR \"animal model\"[All Fields]) OR \"transcriptom*\"[All Fields] OR \"proteom*\"[All Fields] OR \"single-cell\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42865140",
    "42860230",
    "42859505",
    "42859403",
    "42858776",
    "42858071",
    "42858043",
    "42857991",
    "42857971",
    "42853709",
    "42848843",
    "42848775",
    "42842028",
    "42839658",
    "42773990",
    "42501031"
   ]
  },
  "primary_pdat:imaging_biomechanics": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (imaging OR surveillance OR magnetic resonance OR computed tomography OR echocardiography OR biomechanics OR wall stress OR flow OR measurement)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 20,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"image s\"[All Fields] OR \"imaged\"[All Fields] OR \"imager\"[All Fields] OR \"imager s\"[All Fields] OR \"imagers\"[All Fields] OR \"images\"[All Fields] OR \"imaging\"[All Fields] OR \"imaging s\"[All Fields] OR \"imagings\"[All Fields] OR \"intrauterine growth retardation metaphyseal dysplasia adrenal hypoplasia congenita and genital anomalies\"[Supplementary Concept] OR \"intrauterine growth retardation metaphyseal dysplasia adrenal hypoplasia congenita and genital anomalies\"[All Fields] OR \"image\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"surveillance\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"surveilance\"[All Fields] OR \"surveillances\"[All Fields] OR \"surveilled\"[All Fields] OR \"surveillence\"[All Fields]) OR (\"magnetic resonance spectroscopy\"[MeSH Terms] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields] AND \"spectroscopy\"[All Fields]) OR \"magnetic resonance spectroscopy\"[All Fields] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields]) OR \"magnetic resonance\"[All Fields]) OR (\"tomography, x ray computed\"[MeSH Terms] OR (\"tomography\"[All Fields] AND \"x ray\"[All Fields] AND \"computed\"[All Fields]) OR \"x-ray computed tomography\"[All Fields] OR (\"computed\"[All Fields] AND \"tomography\"[All Fields]) OR \"computed tomography\"[All Fields]) OR (\"echocardiographies\"[All Fields] OR \"echocardiography\"[MeSH Terms] OR \"echocardiography\"[All Fields]) OR (\"biomechanical phenomena\"[MeSH Terms] OR (\"biomechanical\"[All Fields] AND \"phenomena\"[All Fields]) OR \"biomechanical phenomena\"[All Fields] OR \"biomechanic\"[All Fields] OR \"biomechanics\"[All Fields] OR \"biomechanical\"[All Fields] OR \"biomechanically\"[All Fields]) OR (\"wall\"[All Fields] AND (\"stress\"[All Fields] OR \"stressed\"[All Fields] OR \"stresses\"[All Fields] OR \"stressful\"[All Fields] OR \"stressfulness\"[All Fields] OR \"stressing\"[All Fields])) OR (\"flow camb\"[Journal] OR \"flow\"[All Fields]) OR (\"measurability\"[All Fields] OR \"measurable\"[All Fields] OR \"measurably\"[All Fields] OR \"measure s\"[All Fields] OR \"measureable\"[All Fields] OR \"measured\"[All Fields] OR \"measurement\"[All Fields] OR \"measurement s\"[All Fields] OR \"measurements\"[All Fields] OR \"measurer\"[All Fields] OR \"measurers\"[All Fields] OR \"measuring\"[All Fields] OR \"measurings\"[All Fields] OR \"measurment\"[All Fields] OR \"measurments\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"measure\"[All Fields] OR \"measures\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42865140",
    "42862301",
    "42862110",
    "42860230",
    "42859505",
    "42859403",
    "42858776",
    "42854006",
    "42853709",
    "42850572",
    "42849511",
    "42848843",
    "42847576",
    "42842028",
    "42841288",
    "42839659",
    "42839658",
    "42593381",
    "42501031",
    "40680099"
   ]
  },
  "primary_pdat:risk_biomarkers": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (risk prediction OR risk stratification OR threshold OR diameter OR biomarker OR microRNA)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 11,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (((\"risk\"[MeSH Terms] OR \"risk\"[All Fields]) AND (\"predict\"[All Fields] OR \"predictabilities\"[All Fields] OR \"predictability\"[All Fields] OR \"predictable\"[All Fields] OR \"predictably\"[All Fields] OR \"predicted\"[All Fields] OR \"predicting\"[All Fields] OR \"prediction\"[All Fields] OR \"predictions\"[All Fields] OR \"predictive\"[All Fields] OR \"predictively\"[All Fields] OR \"predictiveness\"[All Fields] OR \"predictives\"[All Fields] OR \"predictivities\"[All Fields] OR \"predictivity\"[All Fields] OR \"predicts\"[All Fields])) OR ((\"risk\"[MeSH Terms] OR \"risk\"[All Fields]) AND (\"stratification\"[All Fields] OR \"stratifications\"[All Fields])) OR (\"threshold\"[All Fields] OR \"thresholds\"[All Fields]) OR (\"diameter\"[All Fields] OR \"diameters\"[All Fields]) OR (\"biomarker s\"[All Fields] OR \"biomarkers\"[Supplementary Concept] OR \"biomarkers\"[All Fields] OR \"biomarker\"[All Fields] OR \"biomarkers\"[MeSH Terms]) OR (\"microrna s\"[All Fields] OR \"micrornas\"[Supplementary Concept] OR \"micrornas\"[All Fields] OR \"microrna\"[All Fields] OR \"micrornas\"[MeSH Terms])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42869089",
    "42868953",
    "42865140",
    "42864670",
    "42858043",
    "42857971",
    "42854006",
    "42849511",
    "42848775",
    "42841288",
    "40680099"
   ]
  },
  "primary_pdat:medical_exercise_safety": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (drug OR therapy OR losartan OR beta-blocker OR angiotensin OR exercise OR pregnancy OR fluoroquinolone)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 10,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"drug\"[All Fields] OR (\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"therapies\"[All Fields] OR \"therapy\"[MeSH Subheading] OR \"therapy\"[All Fields] OR \"therapy s\"[All Fields] OR \"therapys\"[All Fields]) OR (\"losartan\"[Supplementary Concept] OR \"losartan\"[All Fields] OR \"losartan\"[MeSH Terms] OR \"losartan s\"[All Fields] OR \"losartane\"[All Fields]) OR (\"adrenergic beta antagonists\"[Pharmacological Action] OR \"adrenergic beta antagonists\"[Supplementary Concept] OR \"adrenergic beta antagonists\"[All Fields] OR \"beta blocker\"[All Fields] OR \"adrenergic beta antagonists\"[MeSH Terms] OR (\"adrenergic\"[All Fields] AND \"beta antagonists\"[All Fields]) OR (\"beta\"[All Fields] AND \"blocker\"[All Fields])) OR (\"angiotensin s\"[All Fields] OR \"angiotensine\"[All Fields] OR \"angiotensins\"[Supplementary Concept] OR \"angiotensins\"[All Fields] OR \"angiotensin\"[All Fields] OR \"angiotensins\"[MeSH Terms]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"pregnancy\"[MeSH Terms] OR \"pregnancy\"[All Fields] OR \"pregnancies\"[All Fields] OR \"pregnancy s\"[All Fields]) OR (\"fluoroquinolon\"[All Fields] OR \"fluoroquinolones\"[Supplementary Concept] OR \"fluoroquinolones\"[All Fields] OR \"fluoroquinolone\"[All Fields] OR \"fluoroquinolones\"[MeSH Terms] OR \"fluoroquinolonic\"[All Fields] OR \"fluoroquinolons\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42864670",
    "42862110",
    "42860230",
    "42859505",
    "42859403",
    "42858776",
    "42858043",
    "42848843",
    "42841288",
    "42839658"
   ]
  },
  "primary_pdat:surgery_devices": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (surgery OR surgical OR endovascular OR TEVAR OR valve-sparing OR stent OR repair)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 22,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"surgery\"[MeSH Subheading] OR \"surgery\"[All Fields] OR \"surgical procedures, operative\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"procedures\"[All Fields] AND \"operative\"[All Fields]) OR \"operative surgical procedures\"[All Fields] OR \"general surgery\"[MeSH Terms] OR (\"general\"[All Fields] AND \"surgery\"[All Fields]) OR \"general surgery\"[All Fields] OR \"surgery s\"[All Fields] OR \"surgerys\"[All Fields] OR \"surgeries\"[All Fields] OR (\"surgical procedures, operative\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"procedures\"[All Fields] AND \"operative\"[All Fields]) OR \"operative surgical procedures\"[All Fields] OR \"surgical\"[All Fields] OR \"surgically\"[All Fields] OR \"surgicals\"[All Fields]) OR \"endovascular\"[All Fields] OR (\"endovascular aneurysm repair\"[MeSH Terms] OR (\"endovascular\"[All Fields] AND \"aneurysm\"[All Fields] AND \"repair\"[All Fields]) OR \"endovascular aneurysm repair\"[All Fields] OR \"tevar\"[All Fields] OR \"tevars\"[All Fields]) OR \"valve-sparing\"[All Fields] OR (\"stent s\"[All Fields] OR \"stentings\"[All Fields] OR \"stents\"[MeSH Terms] OR \"stents\"[All Fields] OR \"stent\"[All Fields] OR \"stented\"[All Fields] OR \"stenting\"[All Fields]) OR (\"repairability\"[All Fields] OR \"repairable\"[All Fields] OR \"repaire\"[All Fields] OR \"repaired\"[All Fields] OR \"repairment\"[All Fields] OR \"wound healing\"[MeSH Terms] OR (\"wound\"[All Fields] AND \"healing\"[All Fields]) OR \"wound healing\"[All Fields] OR \"repair\"[All Fields] OR \"repairing\"[All Fields] OR \"repairs\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42869089",
    "42868953",
    "42865140",
    "42864670",
    "42862110",
    "42860230",
    "42859505",
    "42859403",
    "42858043",
    "42857991",
    "42854006",
    "42849511",
    "42848843",
    "42848775",
    "42847578",
    "42847576",
    "42841288",
    "42839659",
    "42839658",
    "42773990",
    "42593381",
    "42501031"
   ]
  },
  "primary_pdat:dissection": {
   "parameters": {
    "db": "pubmed",
    "term": "\"aortic dissection\"[Title/Abstract]",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 17,
   "translated_query": "\"aortic dissection\"[Title/Abstract] AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42869089",
    "42868953",
    "42864670",
    "42862110",
    "42859505",
    "42858071",
    "42858043",
    "42857991",
    "42857971",
    "42854033",
    "42854006",
    "42853709",
    "42850572",
    "42849511",
    "42839659",
    "42773990",
    "42593381"
   ]
  },
  "primary_pdat:guidelines": {
   "parameters": {
    "db": "pubmed",
    "term": "(aort* OR Marfan OR Loeys-Dietz OR vascular Ehlers-Danlos OR Turner) AND (guideline OR consensus OR scientific statement OR position statement OR Ghent)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 12,
   "translated_query": "(\"aort*\"[All Fields] OR (\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields]) OR \"Loeys-Dietz\"[All Fields] OR ((\"blood vessels\"[MeSH Terms] OR (\"blood\"[All Fields] AND \"vessels\"[All Fields]) OR \"blood vessels\"[All Fields] OR \"vascular\"[All Fields] OR \"vascularisation\"[All Fields] OR \"neovascularization, pathologic\"[MeSH Terms] OR (\"neovascularization\"[All Fields] AND \"pathologic\"[All Fields]) OR \"pathologic neovascularization\"[All Fields] OR \"vascularization\"[All Fields] OR \"vascularisations\"[All Fields] OR \"vascularise\"[All Fields] OR \"vascularised\"[All Fields] OR \"vascularities\"[All Fields] OR \"vascularitis\"[All Fields] OR \"vascularity\"[All Fields] OR \"vascularizations\"[All Fields] OR \"vascularize\"[All Fields] OR \"vascularized\"[All Fields] OR \"vascularizes\"[All Fields] OR \"vascularizing\"[All Fields] OR \"vasculars\"[All Fields]) AND \"Ehlers-Danlos\"[All Fields]) OR (\"turner\"[All Fields] OR \"turner s\"[All Fields] OR \"turners\"[All Fields])) AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]) OR ((\"science\"[MeSH Terms] OR \"science\"[All Fields] OR \"scientific\"[All Fields] OR \"scientifical\"[All Fields] OR \"scientifically\"[All Fields] OR \"scientification\"[All Fields] OR \"scientificity\"[All Fields] OR \"scientifics\"[All Fields]) AND (\"statement\"[All Fields] OR \"statement s\"[All Fields] OR \"statements\"[All Fields])) OR ((\"patient positioning\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"positioning\"[All Fields]) OR \"patient positioning\"[All Fields] OR \"positioning\"[All Fields] OR \"position\"[All Fields] OR \"position s\"[All Fields] OR \"positional\"[All Fields] OR \"positioned\"[All Fields] OR \"positionings\"[All Fields] OR \"positions\"[All Fields]) AND (\"statement\"[All Fields] OR \"statement s\"[All Fields] OR \"statements\"[All Fields])) OR \"Ghent\"[All Fields]) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42866921",
    "42863075",
    "42862939",
    "42862070",
    "42859403",
    "42856077",
    "42853682",
    "42843586",
    "42841221",
    "42839659",
    "42839658",
    "42839649"
   ]
  },
  "primary_pdat:patient_experience": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (patient reported OR quality of life OR qualitative OR psychosocial OR awareness OR shared decision OR rehabilitation)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 9,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]) OR (\"psychosocial\"[All Fields] OR \"psychosocially\"[All Fields]) OR (\"awareness\"[MeSH Terms] OR \"awareness\"[All Fields] OR \"aware\"[All Fields] OR \"awarenesses\"[All Fields]) OR ((\"share\"[All Fields] OR \"shared\"[All Fields] OR \"shares\"[All Fields] OR \"sharing\"[All Fields] OR \"sharings\"[All Fields]) AND (\"decision\"[All Fields] OR \"decision s\"[All Fields] OR \"decisions\"[All Fields] OR \"decisive\"[All Fields] OR \"decisively\"[All Fields])) OR (\"rehabilitant\"[All Fields] OR \"rehabilitants\"[All Fields] OR \"rehabilitate\"[All Fields] OR \"rehabilitated\"[All Fields] OR \"rehabilitates\"[All Fields] OR \"rehabilitating\"[All Fields] OR \"rehabilitation\"[MeSH Terms] OR \"rehabilitation\"[All Fields] OR \"rehabilitations\"[All Fields] OR \"rehabilitative\"[All Fields] OR \"rehabilitation\"[MeSH Subheading] OR \"rehabilitation s\"[All Fields] OR \"rehabilitational\"[All Fields] OR \"rehabilitator\"[All Fields] OR \"rehabilitators\"[All Fields])) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42859505",
    "42854033",
    "42850572",
    "42847578",
    "42847576",
    "42839659",
    "42839658",
    "42593381",
    "42501031"
   ]
  },
  "primary_pdat:cochrane": {
   "parameters": {
    "db": "pubmed",
    "term": "\"Cochrane Database Syst Rev\"[jour] AND (aort* OR Marfan OR aneurysm*)",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 0,
   "translated_query": "\"Cochrane Database Syst Rev\"[Journal] AND (\"aort*\"[All Fields] OR (\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields]) OR \"aneurysm*\"[All Fields]) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": []
  },
  "primary_pdat:systematic_reviews": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract] OR Marfan[Title/Abstract] OR Loeys-Dietz[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (systematic review[pt] OR meta-analysis[pt] OR \"systematic review\"[Title/Abstract] OR \"meta-analysis\"[Title/Abstract])",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 3,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract] OR \"Marfan\"[Title/Abstract] OR \"Loeys-Dietz\"[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (\"systematic review\"[Publication Type] OR \"meta-analysis\"[Publication Type] OR \"systematic review\"[Title/Abstract] OR \"meta-analysis\"[Title/Abstract]) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": [
    "42852470",
    "42849511",
    "42839658"
   ]
  },
  "primary_pdat:trials_pt": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract] OR Marfan[Title/Abstract] OR Loeys-Dietz[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt])",
    "mindate": "2026/10/07",
    "maxdate": "2026/10/14",
    "datetype": "pdat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 0,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract] OR \"Marfan\"[Title/Abstract] OR \"Loeys-Dietz\"[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (\"randomized controlled trial\"[Publication Type] OR \"clinical trial\"[Publication Type]) AND 2026/10/07:2026/10/14[Date - Publication]",
   "pmids": []
  },
  "gap_edat:all_thoracic": {
   "parameters": {
    "db": "pubmed",
    "term": "\"aortic aneurysm, thoracic\"[MeSH Terms] OR (thoracic[Title/Abstract] AND aortic[Title/Abstract] AND aneurysm*[Title/Abstract])",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 11,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR (\"thoracic\"[Title/Abstract] AND \"aortic\"[Title/Abstract] AND \"aneurysm*\"[Title/Abstract])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838282",
    "42835868",
    "42833579",
    "42831328",
    "42831135",
    "42830829",
    "42829835",
    "42824407",
    "42818859",
    "42818849",
    "42818172"
   ]
  },
  "gap_edat:epidemiology": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (epidemiology OR incidence OR prevalence OR growth OR natural history OR registry OR burden OR mortality)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 10,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"epidemiologies\"[All Fields] OR \"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"epidemiology s\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields]) OR (\"growth and development\"[MeSH Subheading] OR (\"growth\"[All Fields] AND \"development\"[All Fields]) OR \"growth and development\"[All Fields] OR \"growth\"[All Fields] OR \"growth\"[MeSH Terms] OR \"growths\"[All Fields]) OR (\"natural history\"[MeSH Terms] OR (\"natural\"[All Fields] AND \"history\"[All Fields]) OR \"natural history\"[All Fields]) OR (\"registries\"[MeSH Terms] OR \"registries\"[All Fields] OR \"registry\"[All Fields] OR \"registry s\"[All Fields]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838846",
    "42838142",
    "42834101",
    "42833579",
    "42822618",
    "42822608",
    "42819177",
    "42819164",
    "42818859",
    "42818172"
   ]
  },
  "gap_edat:genetics_syndromes": {
   "parameters": {
    "db": "pubmed",
    "term": "(Marfan OR Loeys-Dietz OR vascular Ehlers-Danlos OR Turner OR (\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract])) AND (aort* AND (genetic* OR heritable OR variant OR syndrome OR screening))",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 9,
   "translated_query": "(\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields] OR \"Loeys-Dietz\"[All Fields] OR ((\"blood vessels\"[MeSH Terms] OR (\"blood\"[All Fields] AND \"vessels\"[All Fields]) OR \"blood vessels\"[All Fields] OR \"vascular\"[All Fields] OR \"vascularisation\"[All Fields] OR \"neovascularization, pathologic\"[MeSH Terms] OR (\"neovascularization\"[All Fields] AND \"pathologic\"[All Fields]) OR \"pathologic neovascularization\"[All Fields] OR \"vascularization\"[All Fields] OR \"vascularisations\"[All Fields] OR \"vascularise\"[All Fields] OR \"vascularised\"[All Fields] OR \"vascularities\"[All Fields] OR \"vascularitis\"[All Fields] OR \"vascularity\"[All Fields] OR \"vascularizations\"[All Fields] OR \"vascularize\"[All Fields] OR \"vascularized\"[All Fields] OR \"vascularizes\"[All Fields] OR \"vascularizing\"[All Fields] OR \"vasculars\"[All Fields]) AND \"Ehlers-Danlos\"[All Fields]) OR (\"turner\"[All Fields] OR \"turner s\"[All Fields] OR \"turners\"[All Fields]) OR (\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract])) AND (\"aort*\"[All Fields] AND (\"genetic*\"[All Fields] OR (\"heritabilities\"[All Fields] OR \"heritability\"[All Fields] OR \"heritable\"[All Fields] OR \"heritably\"[All Fields]) OR (\"variant\"[All Fields] OR \"variant s\"[All Fields] OR \"variants\"[All Fields]) OR (\"syndrom\"[All Fields] OR \"syndromal\"[All Fields] OR \"syndromally\"[All Fields] OR \"syndrome\"[MeSH Terms] OR \"syndrome\"[All Fields] OR \"syndromes\"[All Fields] OR \"syndrome s\"[All Fields] OR \"syndromic\"[All Fields] OR \"syndroms\"[All Fields]) OR (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields]))) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838142",
    "42834101",
    "42829835",
    "42825862",
    "42823940",
    "42820018",
    "42822608",
    "42818859",
    "42818172"
   ]
  },
  "gap_edat:bicuspid": {
   "parameters": {
    "db": "pubmed",
    "term": "(bicuspid aortic valve) AND (aortopathy OR aneurysm OR dilation OR dilatation)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 3,
   "translated_query": "(\"bicuspid aortic valve disease\"[MeSH Terms] OR (\"bicuspid\"[All Fields] AND \"aortic\"[All Fields] AND \"valve\"[All Fields] AND \"disease\"[All Fields]) OR \"bicuspid aortic valve disease\"[All Fields] OR (\"bicuspid\"[All Fields] AND \"aortic\"[All Fields] AND \"valve\"[All Fields]) OR \"bicuspid aortic valve\"[All Fields]) AND (\"aortopathies\"[All Fields] OR \"aortopathy\"[All Fields] OR (\"aneurysm\"[MeSH Terms] OR \"aneurysm\"[All Fields] OR \"aneurysms\"[All Fields] OR \"aneurysm s\"[All Fields] OR \"aneurysmal\"[All Fields] OR \"aneurysmally\"[All Fields] OR \"aneurysmic\"[All Fields]) OR (\"dilatable\"[All Fields] OR \"dilatated\"[All Fields] OR \"dilatating\"[All Fields] OR \"dilatation\"[MeSH Terms] OR \"dilatation\"[All Fields] OR \"dilatations\"[All Fields] OR \"dilate\"[All Fields] OR \"dilation\"[All Fields] OR \"dilations\"[All Fields] OR \"dilatative\"[All Fields] OR \"dilatator\"[All Fields] OR \"dilatators\"[All Fields] OR \"dilated\"[All Fields] OR \"dilates\"[All Fields] OR \"dilating\"[All Fields] OR \"dilator\"[All Fields] OR \"dilators\"[All Fields]) OR (\"dilatable\"[All Fields] OR \"dilatated\"[All Fields] OR \"dilatating\"[All Fields] OR \"dilatation\"[MeSH Terms] OR \"dilatation\"[All Fields] OR \"dilatations\"[All Fields] OR \"dilate\"[All Fields] OR \"dilation\"[All Fields] OR \"dilations\"[All Fields] OR \"dilatative\"[All Fields] OR \"dilatator\"[All Fields] OR \"dilatators\"[All Fields] OR \"dilated\"[All Fields] OR \"dilates\"[All Fields] OR \"dilating\"[All Fields] OR \"dilator\"[All Fields] OR \"dilators\"[All Fields])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42833354",
    "42820635",
    "42817891"
   ]
  },
  "gap_edat:mechanisms_models_omics": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (mechanism OR inflammation OR smooth muscle OR extracellular matrix OR TGF OR mouse OR mice OR animal model OR transcriptom* OR proteom* OR single-cell OR GWAS)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 5,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"mechanism\"[All Fields] OR \"mechanisms\"[All Fields] OR (\"inflammation\"[MeSH Terms] OR \"inflammation\"[All Fields] OR \"inflammations\"[All Fields] OR \"inflammation s\"[All Fields]) OR (\"muscle, smooth\"[MeSH Terms] OR (\"muscle\"[All Fields] AND \"smooth\"[All Fields]) OR \"smooth muscle\"[All Fields] OR (\"smooth\"[All Fields] AND \"muscle\"[All Fields])) OR (\"extracellular matrix\"[MeSH Terms] OR (\"extracellular\"[All Fields] AND \"matrix\"[All Fields]) OR \"extracellular matrix\"[All Fields]) OR \"TGF\"[All Fields] OR (\"mice\"[MeSH Terms] OR \"mice\"[All Fields] OR \"mouse\"[All Fields] OR \"mouse s\"[All Fields] OR \"mouses\"[All Fields]) OR (\"mice\"[MeSH Terms] OR \"mice\"[All Fields]) OR (\"models, animal\"[MeSH Terms] OR (\"models\"[All Fields] AND \"animal\"[All Fields]) OR \"animal models\"[All Fields] OR (\"animal\"[All Fields] AND \"model\"[All Fields]) OR \"animal model\"[All Fields]) OR \"transcriptom*\"[All Fields] OR \"proteom*\"[All Fields] OR \"single-cell\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838846",
    "42834101",
    "42829835",
    "42819177",
    "42818172"
   ]
  },
  "gap_edat:imaging_biomechanics": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (imaging OR surveillance OR magnetic resonance OR computed tomography OR echocardiography OR biomechanics OR wall stress OR flow OR measurement)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 18,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"image s\"[All Fields] OR \"imaged\"[All Fields] OR \"imager\"[All Fields] OR \"imager s\"[All Fields] OR \"imagers\"[All Fields] OR \"images\"[All Fields] OR \"imaging\"[All Fields] OR \"imaging s\"[All Fields] OR \"imagings\"[All Fields] OR \"intrauterine growth retardation metaphyseal dysplasia adrenal hypoplasia congenita and genital anomalies\"[Supplementary Concept] OR \"intrauterine growth retardation metaphyseal dysplasia adrenal hypoplasia congenita and genital anomalies\"[All Fields] OR \"image\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"surveillance\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"surveilance\"[All Fields] OR \"surveillances\"[All Fields] OR \"surveilled\"[All Fields] OR \"surveillence\"[All Fields]) OR (\"magnetic resonance spectroscopy\"[MeSH Terms] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields] AND \"spectroscopy\"[All Fields]) OR \"magnetic resonance spectroscopy\"[All Fields] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields]) OR \"magnetic resonance\"[All Fields]) OR (\"tomography, x ray computed\"[MeSH Terms] OR (\"tomography\"[All Fields] AND \"x ray\"[All Fields] AND \"computed\"[All Fields]) OR \"x-ray computed tomography\"[All Fields] OR (\"computed\"[All Fields] AND \"tomography\"[All Fields]) OR \"computed tomography\"[All Fields]) OR (\"echocardiographies\"[All Fields] OR \"echocardiography\"[MeSH Terms] OR \"echocardiography\"[All Fields]) OR (\"biomechanical phenomena\"[MeSH Terms] OR (\"biomechanical\"[All Fields] AND \"phenomena\"[All Fields]) OR \"biomechanical phenomena\"[All Fields] OR \"biomechanic\"[All Fields] OR \"biomechanics\"[All Fields] OR \"biomechanical\"[All Fields] OR \"biomechanically\"[All Fields]) OR (\"wall\"[All Fields] AND (\"stress\"[All Fields] OR \"stressed\"[All Fields] OR \"stresses\"[All Fields] OR \"stressful\"[All Fields] OR \"stressfulness\"[All Fields] OR \"stressing\"[All Fields])) OR (\"flow camb\"[Journal] OR \"flow\"[All Fields]) OR (\"measurability\"[All Fields] OR \"measurable\"[All Fields] OR \"measurably\"[All Fields] OR \"measure s\"[All Fields] OR \"measureable\"[All Fields] OR \"measured\"[All Fields] OR \"measurement\"[All Fields] OR \"measurement s\"[All Fields] OR \"measurements\"[All Fields] OR \"measurer\"[All Fields] OR \"measurers\"[All Fields] OR \"measuring\"[All Fields] OR \"measurings\"[All Fields] OR \"measurment\"[All Fields] OR \"measurments\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"measure\"[All Fields] OR \"measures\"[All Fields])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838142",
    "42836819",
    "42835868",
    "42833100",
    "42830829",
    "42828522",
    "42828113",
    "42825862",
    "42823940",
    "42820018",
    "42822618",
    "42822608",
    "42820217",
    "42819177",
    "42818859",
    "42818849",
    "42818172",
    "42817891"
   ]
  },
  "gap_edat:risk_biomarkers": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (risk prediction OR risk stratification OR threshold OR diameter OR biomarker OR microRNA)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 4,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (((\"risk\"[MeSH Terms] OR \"risk\"[All Fields]) AND (\"predict\"[All Fields] OR \"predictabilities\"[All Fields] OR \"predictability\"[All Fields] OR \"predictable\"[All Fields] OR \"predictably\"[All Fields] OR \"predicted\"[All Fields] OR \"predicting\"[All Fields] OR \"prediction\"[All Fields] OR \"predictions\"[All Fields] OR \"predictive\"[All Fields] OR \"predictively\"[All Fields] OR \"predictiveness\"[All Fields] OR \"predictives\"[All Fields] OR \"predictivities\"[All Fields] OR \"predictivity\"[All Fields] OR \"predicts\"[All Fields])) OR ((\"risk\"[MeSH Terms] OR \"risk\"[All Fields]) AND (\"stratification\"[All Fields] OR \"stratifications\"[All Fields])) OR (\"threshold\"[All Fields] OR \"thresholds\"[All Fields]) OR (\"diameter\"[All Fields] OR \"diameters\"[All Fields]) OR (\"biomarker s\"[All Fields] OR \"biomarkers\"[Supplementary Concept] OR \"biomarkers\"[All Fields] OR \"biomarker\"[All Fields] OR \"biomarkers\"[MeSH Terms]) OR (\"microrna s\"[All Fields] OR \"micrornas\"[Supplementary Concept] OR \"micrornas\"[All Fields] OR \"microrna\"[All Fields] OR \"micrornas\"[MeSH Terms])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838142",
    "42833579",
    "42818849",
    "42818172"
   ]
  },
  "gap_edat:medical_exercise_safety": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (drug OR therapy OR losartan OR beta-blocker OR angiotensin OR exercise OR pregnancy OR fluoroquinolone)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 8,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"drug\"[All Fields] OR (\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"therapies\"[All Fields] OR \"therapy\"[MeSH Subheading] OR \"therapy\"[All Fields] OR \"therapy s\"[All Fields] OR \"therapys\"[All Fields]) OR (\"losartan\"[Supplementary Concept] OR \"losartan\"[All Fields] OR \"losartan\"[MeSH Terms] OR \"losartan s\"[All Fields] OR \"losartane\"[All Fields]) OR (\"adrenergic beta antagonists\"[Pharmacological Action] OR \"adrenergic beta antagonists\"[Supplementary Concept] OR \"adrenergic beta antagonists\"[All Fields] OR \"beta blocker\"[All Fields] OR \"adrenergic beta antagonists\"[MeSH Terms] OR (\"adrenergic\"[All Fields] AND \"beta antagonists\"[All Fields]) OR (\"beta\"[All Fields] AND \"blocker\"[All Fields])) OR (\"angiotensin s\"[All Fields] OR \"angiotensine\"[All Fields] OR \"angiotensins\"[Supplementary Concept] OR \"angiotensins\"[All Fields] OR \"angiotensin\"[All Fields] OR \"angiotensins\"[MeSH Terms]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"pregnancy\"[MeSH Terms] OR \"pregnancy\"[All Fields] OR \"pregnancies\"[All Fields] OR \"pregnancy s\"[All Fields]) OR (\"fluoroquinolon\"[All Fields] OR \"fluoroquinolones\"[Supplementary Concept] OR \"fluoroquinolones\"[All Fields] OR \"fluoroquinolone\"[All Fields] OR \"fluoroquinolones\"[MeSH Terms] OR \"fluoroquinolonic\"[All Fields] OR \"fluoroquinolons\"[All Fields])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42835471",
    "42829984",
    "42828522",
    "42825862",
    "42822618",
    "42822608",
    "42819177",
    "42817891"
   ]
  },
  "gap_edat:surgery_devices": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (surgery OR surgical OR endovascular OR TEVAR OR valve-sparing OR stent OR repair)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 21,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (\"surgery\"[MeSH Subheading] OR \"surgery\"[All Fields] OR \"surgical procedures, operative\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"procedures\"[All Fields] AND \"operative\"[All Fields]) OR \"operative surgical procedures\"[All Fields] OR \"general surgery\"[MeSH Terms] OR (\"general\"[All Fields] AND \"surgery\"[All Fields]) OR \"general surgery\"[All Fields] OR \"surgery s\"[All Fields] OR \"surgerys\"[All Fields] OR \"surgeries\"[All Fields] OR (\"surgical procedures, operative\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"procedures\"[All Fields] AND \"operative\"[All Fields]) OR \"operative surgical procedures\"[All Fields] OR \"surgical\"[All Fields] OR \"surgically\"[All Fields] OR \"surgicals\"[All Fields]) OR \"endovascular\"[All Fields] OR (\"endovascular aneurysm repair\"[MeSH Terms] OR (\"endovascular\"[All Fields] AND \"aneurysm\"[All Fields] AND \"repair\"[All Fields]) OR \"endovascular aneurysm repair\"[All Fields] OR \"tevar\"[All Fields] OR \"tevars\"[All Fields]) OR \"valve-sparing\"[All Fields] OR (\"stent s\"[All Fields] OR \"stentings\"[All Fields] OR \"stents\"[MeSH Terms] OR \"stents\"[All Fields] OR \"stent\"[All Fields] OR \"stented\"[All Fields] OR \"stenting\"[All Fields]) OR (\"repairability\"[All Fields] OR \"repairable\"[All Fields] OR \"repaire\"[All Fields] OR \"repaired\"[All Fields] OR \"repairment\"[All Fields] OR \"wound healing\"[MeSH Terms] OR (\"wound\"[All Fields] AND \"healing\"[All Fields]) OR \"wound healing\"[All Fields] OR \"repair\"[All Fields] OR \"repairing\"[All Fields] OR \"repairs\"[All Fields])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838846",
    "42836819",
    "42836437",
    "42835868",
    "42835512",
    "42835471",
    "42834101",
    "42833579",
    "42833295",
    "42830829",
    "42829984",
    "42828113",
    "42823940",
    "42820018",
    "42819734",
    "42822618",
    "42822608",
    "42820217",
    "42819164",
    "42818172",
    "42817891"
   ]
  },
  "gap_edat:dissection": {
   "parameters": {
    "db": "pubmed",
    "term": "\"aortic dissection\"[Title/Abstract]",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 20,
   "translated_query": "\"aortic dissection\"[Title/Abstract] AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838846",
    "42838142",
    "42836819",
    "42836437",
    "42835868",
    "42835512",
    "42835471",
    "42834101",
    "42833295",
    "42833100",
    "42829984",
    "42828522",
    "42823940",
    "42819734",
    "42822618",
    "42820217",
    "42819177",
    "42819164",
    "42818849",
    "42818172"
   ]
  },
  "gap_edat:guidelines": {
   "parameters": {
    "db": "pubmed",
    "term": "(aort* OR Marfan OR Loeys-Dietz OR vascular Ehlers-Danlos OR Turner) AND (guideline OR consensus OR scientific statement OR position statement OR Ghent)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 14,
   "translated_query": "(\"aort*\"[All Fields] OR (\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields]) OR \"Loeys-Dietz\"[All Fields] OR ((\"blood vessels\"[MeSH Terms] OR (\"blood\"[All Fields] AND \"vessels\"[All Fields]) OR \"blood vessels\"[All Fields] OR \"vascular\"[All Fields] OR \"vascularisation\"[All Fields] OR \"neovascularization, pathologic\"[MeSH Terms] OR (\"neovascularization\"[All Fields] AND \"pathologic\"[All Fields]) OR \"pathologic neovascularization\"[All Fields] OR \"vascularization\"[All Fields] OR \"vascularisations\"[All Fields] OR \"vascularise\"[All Fields] OR \"vascularised\"[All Fields] OR \"vascularities\"[All Fields] OR \"vascularitis\"[All Fields] OR \"vascularity\"[All Fields] OR \"vascularizations\"[All Fields] OR \"vascularize\"[All Fields] OR \"vascularized\"[All Fields] OR \"vascularizes\"[All Fields] OR \"vascularizing\"[All Fields] OR \"vasculars\"[All Fields]) AND \"Ehlers-Danlos\"[All Fields]) OR (\"turner\"[All Fields] OR \"turner s\"[All Fields] OR \"turners\"[All Fields])) AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]) OR ((\"science\"[MeSH Terms] OR \"science\"[All Fields] OR \"scientific\"[All Fields] OR \"scientifical\"[All Fields] OR \"scientifically\"[All Fields] OR \"scientification\"[All Fields] OR \"scientificity\"[All Fields] OR \"scientifics\"[All Fields]) AND (\"statement\"[All Fields] OR \"statement s\"[All Fields] OR \"statements\"[All Fields])) OR ((\"patient positioning\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"positioning\"[All Fields]) OR \"patient positioning\"[All Fields] OR \"positioning\"[All Fields] OR \"position\"[All Fields] OR \"position s\"[All Fields] OR \"positional\"[All Fields] OR \"positioned\"[All Fields] OR \"positionings\"[All Fields] OR \"positions\"[All Fields]) AND (\"statement\"[All Fields] OR \"statement s\"[All Fields] OR \"statements\"[All Fields])) OR \"Ghent\"[All Fields]) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838462",
    "42836004",
    "42833583",
    "42832065",
    "42829298",
    "42829021",
    "42826929",
    "42825862",
    "42825173",
    "42824356",
    "42820018",
    "42820889",
    "42818569",
    "42818544"
   ]
  },
  "gap_edat:patient_experience": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract]) AND (patient reported OR quality of life OR qualitative OR psychosocial OR awareness OR shared decision OR rehabilitation)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 10,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract]) AND (((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]) OR (\"psychosocial\"[All Fields] OR \"psychosocially\"[All Fields]) OR (\"awareness\"[MeSH Terms] OR \"awareness\"[All Fields] OR \"aware\"[All Fields] OR \"awarenesses\"[All Fields]) OR ((\"share\"[All Fields] OR \"shared\"[All Fields] OR \"shares\"[All Fields] OR \"sharing\"[All Fields] OR \"sharings\"[All Fields]) AND (\"decision\"[All Fields] OR \"decision s\"[All Fields] OR \"decisions\"[All Fields] OR \"decisive\"[All Fields] OR \"decisively\"[All Fields])) OR (\"rehabilitant\"[All Fields] OR \"rehabilitants\"[All Fields] OR \"rehabilitate\"[All Fields] OR \"rehabilitated\"[All Fields] OR \"rehabilitates\"[All Fields] OR \"rehabilitating\"[All Fields] OR \"rehabilitation\"[MeSH Terms] OR \"rehabilitation\"[All Fields] OR \"rehabilitations\"[All Fields] OR \"rehabilitative\"[All Fields] OR \"rehabilitation\"[MeSH Subheading] OR \"rehabilitation s\"[All Fields] OR \"rehabilitational\"[All Fields] OR \"rehabilitator\"[All Fields] OR \"rehabilitators\"[All Fields])) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42838846",
    "42835868",
    "42835512",
    "42835471",
    "42829984",
    "42828522",
    "42823940",
    "42820018",
    "42819734",
    "42820217"
   ]
  },
  "gap_edat:cochrane": {
   "parameters": {
    "db": "pubmed",
    "term": "\"Cochrane Database Syst Rev\"[jour] AND (aort* OR Marfan OR aneurysm*)",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 0,
   "translated_query": "\"Cochrane Database Syst Rev\"[Journal] AND (\"aort*\"[All Fields] OR (\"marfan\"[All Fields] OR \"marfan s\"[All Fields] OR \"marfans\"[All Fields]) OR \"aneurysm*\"[All Fields]) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": []
  },
  "gap_edat:systematic_reviews": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract] OR Marfan[Title/Abstract] OR Loeys-Dietz[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (systematic review[pt] OR meta-analysis[pt] OR \"systematic review\"[Title/Abstract] OR \"meta-analysis\"[Title/Abstract])",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 1,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract] OR \"Marfan\"[Title/Abstract] OR \"Loeys-Dietz\"[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (\"systematic review\"[Publication Type] OR \"meta-analysis\"[Publication Type] OR \"systematic review\"[Title/Abstract] OR \"meta-analysis\"[Title/Abstract]) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": [
    "42818172"
   ]
  },
  "gap_edat:trials_pt": {
   "parameters": {
    "db": "pubmed",
    "term": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR aortopathy[Title/Abstract] OR aortopathies[Title/Abstract] OR Marfan[Title/Abstract] OR Loeys-Dietz[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt])",
    "mindate": "2026/10/01",
    "maxdate": "2026/10/06",
    "datetype": "edat",
    "retmode": "json",
    "retmax": 1000
   },
   "count": 0,
   "translated_query": "(\"aortic aneurysm, thoracic\"[MeSH Terms] OR \"thoracic aortic\"[Title/Abstract] OR \"ascending aortic\"[Title/Abstract] OR \"aortic dissection\"[Title/Abstract] OR \"aortopathy\"[Title/Abstract] OR \"aortopathies\"[Title/Abstract] OR \"Marfan\"[Title/Abstract] OR \"Loeys-Dietz\"[Title/Abstract] OR \"aortic root\"[Title/Abstract]) AND (\"randomized controlled trial\"[Publication Type] OR \"clinical trial\"[Publication Type]) AND 2026/10/01:2026/10/06[Date - Entry]",
   "pmids": []
  }
 },
 "unique_pubmed_records": 117,
 "pubmed_records": [
  {
   "pmid": "40680099",
   "title": "Visceral adipose tissue, aortic distensibility and atherosclerotic cardiovascular risk across body mass index categories.",
   "journal": "Eur J Prev Cardiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42466795",
   "title": "Endovascular treatment of thoracoabdominal aortic pathologies using 3D printer-assisted physician-modified stent-grafts.",
   "journal": "Turk Gogus Kalp Damar Cerrahisi Derg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42501031",
   "title": "Mycotic Ascending Aortic Pseudoaneurysm With Radial Artery Graft Failure Following Coronary Artery Bypass Surgery.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42593381",
   "title": "First Latin American Experience With a Hybrid Dissection Stent in Type A Aortic Dissection.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42773990",
   "title": "Two acquired causes of acute aortic wall insufficiency: Inflammation and medial degeneration.",
   "journal": "Turk Gogus Kalp Damar Cerrahisi Derg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42817891",
   "title": "Optimal Patient Selection for Aortic Valve and Concomitant Ascending Aortic Procedures: Role of Multimodality Imaging.",
   "journal": "Circ Cardiovasc Imaging",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42818172",
   "title": "Gene-Based Rare Variant Burden Analyses Across Biobanks Identify Novel High-Risk Genes for Thoracic Aortic Disease.",
   "journal": "medRxiv",
   "types": [
    "Journal Article",
    "Preprint"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42818544",
   "title": "Cap-Independent Translation Regulation of VEGF Using CRISPR-dCas13d.",
   "journal": "bioRxiv",
   "types": [
    "Journal Article",
    "Preprint"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42818569",
   "title": "Lipoprotein(a) in the statin era: from risk marker to therapeutic target.",
   "journal": "Front Pharmacol",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42818849",
   "title": "Magnetic Resonance Elastography of Regional Aortic Mechanics and True- and False-Lumen Stiffness in Aortic Dissection: A Feasibility Study.",
   "journal": "medRxiv",
   "types": [
    "Journal Article",
    "Preprint"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42818859",
   "title": "Thoracic Aortic Disease in Genetic Syndromes Beyond Established Aortopathy Genes.",
   "journal": "medRxiv",
   "types": [
    "Journal Article",
    "Preprint"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42819164",
   "title": "Impact of body mass index on outcomes in acute type A aortic dissection.",
   "journal": "Front Cardiovasc Med",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42819177",
   "title": "Targeted Catalytic Anti-Inflammatory and Antioxidant Therapy for Aortic Dissection Using Biomimetic Nanomaterials.",
   "journal": "ACS Omega",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42819734",
   "title": "Recurrent Type A Aortic Dissection and New Entry after Endovascular Repair.",
   "journal": "Ann Vasc Dis",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42820018",
   "title": "FBN1 Variant of Uncertain Significance in a Patient With a Marfan Spectrum Phenotype: A Case Report.",
   "journal": "Cureus",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42820217",
   "title": "From stent to stability: Conservative management of post-stenting aortic dissection in coarctation of the aorta.",
   "journal": "Ann Pediatr Cardiol",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42820635",
   "title": "Unicuspid Aortic Valve Presenting With Severe Aortic Regurgitation and Successfully Repaired by Bicuspidization.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42820889",
   "title": "Automated Aortic Valve Calcification Scoring: Multicenter External Validation of a Deep Learning Algorithm.",
   "journal": "JACC Adv",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42822608",
   "title": "Selective Endovascular Aortic Repair in Connective Tissue Disease Patients Within a Multidisciplinary Program Achieves Comparable Outcomes in High-Risk Patients.",
   "journal": "J Vasc Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42822618",
   "title": "Surgery for Acute Type A Aortic Dissection on Preoperative Anticoagulants and Antiplatelet Agents.",
   "journal": "Ann Thorac Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42823940",
   "title": "Duodenal Obstruction and Grade III Acute Cholangitis Following Pancreaticoduodenal Artery Aneurysm Rupture During Conservative Management of Acute Type B Aortic Dissection: A Case Report.",
   "journal": "Cureus",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42824356",
   "title": "Comparison of Sizing Methods to Optimize Device Selection for Percutaneous Closure of Atrial Septal Defects.",
   "journal": "Cardiol Res Pract",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42824407",
   "title": "Fenestrated and branched technologies in complex aortic aneurysm care.",
   "journal": "Turk Gogus Kalp Damar Cerrahisi Derg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42825173",
   "title": "No Environment, No Education: Honoring the Clinical Learning Environment as the Engine of Competency-Based Education - A Call to Action.",
   "journal": "Perspect Med Educ",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42825862",
   "title": "Allopurinol for Marfan Aortopathy: Pharmacogenomic Safety and Sex-Stratified Trial Design Warrant Consideration.",
   "journal": "Cardiovasc Drugs Ther",
   "types": [
    "Letter"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42826929",
   "title": "Wearables for Physical Activity Guideline Development and Health Surveillance: Converging Research and Practice Agendas.",
   "journal": "J Phys Act Health",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42828113",
   "title": "Recurrent thoracic aortic stent graft thrombosis.",
   "journal": "J Vasc Surg Cases Innov Tech",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42828522",
   "title": "Iatrogenic Crescentic Hematoma of the Right Sinus of Valsalva: A Diagnostic Pitfall Mimicking Aortic Root Dissection.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42829021",
   "title": "Compromised elastin network load transfer in aging human aorta.",
   "journal": "Acta Biomater",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42829298",
   "title": "The SOAR project: Developing a framework for screening for older adults' abuse risk.",
   "journal": "Int Psychogeriatr",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42829835",
   "title": "Loss of function variants in ADAMTS6: a new connective tissue disorder with heart defect, aortic aneurysm and neurodevelopmental features.",
   "journal": "Genet Med",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42829984",
   "title": "Readiness for Hospital Discharge and Quality of Life Among Patients Undergoing Surgery for Type A Aortic Dissection: A Prospective Observational Cohort Study.",
   "journal": "Nurs Open",
   "types": [
    "Journal Article",
    "Observational Study"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42830829",
   "title": "Type III endoleaks following endovascular aortic repair: a case series.",
   "journal": "J Surg Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42831135",
   "title": "Aortic coarctation revealed by subarachnoid hemorrhage in a 17-year-old patient: A rare association with multiple basilar trunk aneurysms.",
   "journal": "Radiol Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42831328",
   "title": "[Prognostic significance of no recovery of motor evoked potentials and H-reflex in open thoracoabdominal aortic repair].",
   "journal": "Khirurgiia (Mosk)",
   "types": [
    "Journal Article",
    "English Abstract",
    "Observational Study"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42832065",
   "title": "Known Unknowns: Unpacking Controversies and Uncertainties in the 2025 Guidelines for Management of Acute Coronary Syndromes.",
   "journal": "Curr Cardiol Rep",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42833100",
   "title": "Prior-driven multimodal contrastive learning with Fourier cross-attention to detect aortic dissection in 3D non-contrast CT.",
   "journal": "Comput Med Imaging Graph",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42833295",
   "title": "Heparin Management and Coagulation in Acute Aortic Dissection Surgery: A Randomised Controlled Trial.",
   "journal": "J Thromb Haemost",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42833354",
   "title": "Pediatric Aortic Valve Repair - Reproducible Using Adult Concepts.",
   "journal": "J Thorac Cardiovasc Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42833579",
   "title": "Proximal Neck Diameter Changes Following Zone 0 TEVAR With or Without Ascending Aortic Wrapping.",
   "journal": "Ann Vasc Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42833583",
   "title": "Health-Related Quality of Life After Open and Endovascular Revascularization for Aortoiliac Occlusive Disease: A Prospective Cohort Study.",
   "journal": "Ann Vasc Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42834101",
   "title": "TNALP associated calcium phosphate microdeposition contributes to thoracic aortic dissection susceptibility.",
   "journal": "Commun Biol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42835471",
   "title": "Complex management of extensive perivisceral aortic thrombus and associated chronic kidney disease in a 70-year-old woman.",
   "journal": "J Vasc Surg Cases Innov Tech",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42835512",
   "title": "Bilateral internal iliac preservation using a short-tip distal branched custom-made device during fenestrated or branched aortic repair.",
   "journal": "J Vasc Surg Cases Innov Tech",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42835868",
   "title": "Acute type B aortic dissection after ruptured thoracoabdominal aortic aneurysm repair resulting in thoracoabdominal branch endoprosthesis collapse and malperfusion.",
   "journal": "J Vasc Surg Cases Innov Tech",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42836004",
   "title": "Carbon dioxide as a promising alternative to iodinated contrast media for lower extremity endovascular procedures (Review).",
   "journal": "Biomed Rep",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42836437",
   "title": "Accidental stent-graft deployment into the false lumen during thoracic endovascular aortic repair for Stanford type B aortic dissection after Bentall procedure, salvaged by re-stenting via the true lumen.",
   "journal": "Eur Heart J",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42836819",
   "title": "Primary Aortic Wall Myxoma Presenting With Recurrent Systemic Embolization: A Hybrid Surgical Management Strategy.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42838142",
   "title": "Long-term cardiovascular morbidity and mortality in Turner syndrome patients with congenital heart disease: a single-center retrospective cohort study.",
   "journal": "Int J Cardiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42838282",
   "title": "Clostridium septicum Aortitis and Mediastinitis Complicating Perforated Appendicitis in a Patient with Chronic Myelomonocytic Leukemia: A Case Report.",
   "journal": "J Infect Chemother",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42838462",
   "title": "MOLECULAR AND CLINICAL FEATURES OF KYPHOSCOLIOTIC EHLERS-DANLOS SYNDROME DUE TO LYSYL HYDROXYLASE 1 DEFICIENCY.",
   "journal": "Matrix Biol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42838846",
   "title": "Surgery for Acute Type A Aortic Dissection in Patients Aged ≥75 Years: Six-Month Outcomes and Predictors of Mortality.",
   "journal": "J Cardiothorac Vasc Anesth",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42839649",
   "title": "EACTS Expert Consensus Document on Civil Aviation Following Cardiothoracic Surgery and Transcatheter Procedures.",
   "journal": "Interdiscip Cardiovasc Thorac Surg",
   "types": [
    "Journal Article",
    "Consensus Statement",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42839658",
   "title": "EACTS Expert Consensus Document on aortic valve repair and valve-sparing aortic root replacement procedures.",
   "journal": "Eur J Cardiothorac Surg",
   "types": [
    "Consensus Statement",
    "Journal Article",
    "Systematic Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42839659",
   "title": "EACTS Expert Consensus Document on Iatrogenic Aortic Dissection.",
   "journal": "Eur J Cardiothorac Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42840784",
   "title": "A BENCHTOP PLATFORM FOR EVALUATING SEPTOSTOMY IN AORTIC DISSECTION.",
   "journal": "Proc Des Med Devices Conf",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42840921",
   "title": "Single-stage hybrid repair of extensive aortic dissection with traumatic diaphragmatic hernia.",
   "journal": "Trauma Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42841221",
   "title": "Reallocation of 24-hour movement behaviour composition and mortality: exploring effect modification by sleep characteristics.",
   "journal": "Am J Epidemiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42841288",
   "title": "Circulatory arrest versus aortic cross-clamping in proximal thoracic aortic aneurysm repair.",
   "journal": "Scand Cardiovasc J",
   "types": [
    "Journal Article",
    "Comparative Study",
    "Observational Study"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42842028",
   "title": "Computational multiscale analysis of growth and remodeling in the ascending aorta of the Marfan mouse.",
   "journal": "Biomech Model Mechanobiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42842764",
   "title": "Bacterial aortic endarteritis with sepsis as a rare complication of aortic dissection in a cat.",
   "journal": "J Vet Intern Med",
   "types": [
    "Journal Article",
    "Case Reports"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42843586",
   "title": "Impact of different conduction disturbance management strategies after TAVI on 1-year clinical outcomes: the GLAM-TAVI registry.",
   "journal": "Rev Esp Cardiol (Engl Ed)",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42846901",
   "title": "DEVELOPMENT AND PRELIMINARY BENCHTOP EVALUATION OF A NOVEL ATHERMAL SEPTOSTOMY CATHETER.",
   "journal": "Proc Des Med Devices Conf",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42847576",
   "title": "Endovascular Solution for Anastomotic Pseudoaneurysm of the Ascending Aorta.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42847578",
   "title": "Total Thoracic Aortic \"Pericardialization\" for Multilevel Prosthetic Graft Infection.",
   "journal": "JACC Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42848775",
   "title": "Identification of shared diagnostic biomarkers and immune-related mechanisms between sepsis and thoracic aortic aneurysm based on integrated bioinformatics and machine learning approaches.",
   "journal": "PLoS One",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42848843",
   "title": "A single-aortotomy end-to-side technique simplifies murine aortic transplantation.",
   "journal": "PLoS One",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42849511",
   "title": "Marfan Syndrome versus Loeys-Dietz Syndrome after Aortic Surgery: A Systematic Review and Meta-analysis of Reconstructed Time-to-Event Data.",
   "journal": "Aorta (Stamford)",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42850148",
   "title": "Prevalence and determinants of thoracic aortic dilatation detected by focused cardiac ultrasound in recreational and competitive sport participants.",
   "journal": "J Sci Med Sport",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42850572",
   "title": "The risk of not imaging: a three-scenario framework for justification.",
   "journal": "Br J Radiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42852470",
   "title": "The association between collagenopathies and the risk of spontaneous preterm birth: A systematic review with selective meta-analysis.",
   "journal": "Acta Obstet Gynecol Scand",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42853682",
   "title": "Targeting Lipoprotein(a) in Cardiovascular Disease: Emerging Therapies and Clinical Implications.",
   "journal": "J Cardiovasc Pharmacol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42853709",
   "title": "Stanford type A aortic dissection in long-standing Langerhans cell histiocytosis: a possible association.",
   "journal": "Acta Cardiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42854006",
   "title": "Admission blood glucose and neutrophil-to-lymphocyte ratio provide independent and complementary prognostic value for in-hospital mortality in acute type A aortic dissection.",
   "journal": "Medicine (Baltimore)",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42854033",
   "title": "ST elevation in lead aVR - a marker of critical left main coronary artery stenosis: A series of case reports and literature review.",
   "journal": "Medicine (Baltimore)",
   "types": [
    "Journal Article",
    "Review",
    "Case Reports"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42855421",
   "title": "Preoperative Mechanical Thrombectomy in Ischemic Stroke Complicating Acute Type A Aortic Dissection.",
   "journal": "J Cardiothorac Vasc Anesth",
   "types": [
    "Letter"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42855990",
   "title": "Artificial Intelligence Echocardiographic Interpretation in the Emergency Department: Agreement, Interpretation Yield and Reporting Scope.",
   "journal": "Emerg Med Australas",
   "types": [
    "Journal Article",
    "Multicenter Study"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42856077",
   "title": "Optimizing management strategies for T4b esophageal cancer: the role of TEVAR in multimodal treatment approaches.",
   "journal": "Scand J Gastroenterol",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42857389",
   "title": "Complex surgical management of right-sided infective endocarditis following ventricular septal defect closure with residual shunt and ascending aortic pseudoaneurysm: a case report.",
   "journal": "Int J Surg Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42857632",
   "title": "Enhanced recovery after surgery turnkey order set for periprocedural care of the patient undergoing transcatheter aortic valve replacement.",
   "journal": "JTCVS Struct Endovasc",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42857752",
   "title": "External iliac artery dissection associated with resuscitative endovascular balloon occlusion of the aorta (REBOA) removal: a case report.",
   "journal": "Int J Surg Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42857757",
   "title": "The 'R sign' as a potential risk factor for progression of uncomplicated Type B aortic dissection: a case series.",
   "journal": "Eur Heart J Case Rep",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42857971",
   "title": "TRPC1 Promotes Thoracic Aortic Dissection Through Inducing Proinflammatory Phenotype of Vascular Smooth Muscle Cells.",
   "journal": "J Am Heart Assoc",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42857991",
   "title": "Whole-Genome Sequencing and Single-Cell Transcriptomics Identify Human Leukocyte Antigen Loci and a COG5 Variant in Aortic Dissection.",
   "journal": "J Am Heart Assoc",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42858043",
   "title": "Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Sheath Microinjection of Chymotrypsin.",
   "journal": "J Vis Exp",
   "types": [
    "Journal Article",
    "Video-Audio Media"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42858071",
   "title": "Isolation and Culture of Primary Murine Aortic Smooth Muscle Cells for In vitro Studies Relevant to Vascular Remodeling and Aortic Aneurysm Biology.",
   "journal": "J Vis Exp",
   "types": [
    "Journal Article",
    "Video-Audio Media"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42858776",
   "title": "Vasorelaxant and antihypertensive effects of salicylaldehyde: Involvement of renin-angiotensin system and calcium/potassium channel modulation.",
   "journal": "Eur J Pharmacol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859403",
   "title": "Complications associated with thoracic endovascular aortic repair: highlighting the role of peri- and post-operative cardiac monitoring.",
   "journal": "Expert Rev Cardiovasc Ther",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859505",
   "title": "Suspected Mesenteric Malperfusion in Acute Type A Aortic Dissection During Pregnancy: A Case Report and Review of Reperfusion-First Strategies.",
   "journal": "Clin Case Rep",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859523",
   "title": "Single-Stage Computed Tomography Angiography, Percutaneous Coronary Intervention, and Transcatheter Aortic Valve Replacement in an Octogenarian With Femoral Neck Fracture, Non-ST-Elevation Myocardial Infarction, and Severe Aortic Stenosis: A Case Report and Literature Review of Multidisciplinary Approaches.",
   "journal": "Rev Cardiovasc Med",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859541",
   "title": "Analysis of Postoperative Quality of Life in Patients With Acute Type A Aortic Dissection After Extensive Arch Repair via Partial Upper Sternotomy.",
   "journal": "Rev Cardiovasc Med",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859704",
   "title": "Application of Non-Invasive Cardiac Output Monitoring in Enhanced Recovery After Surgery for Patients With Acute Type A Aortic Dissection.",
   "journal": "Rev Cardiovasc Med",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859721",
   "title": "The Role of Autoimmune Diseases in the Development of Aortic Aneurysms.",
   "journal": "Rev Cardiovasc Med",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42859743",
   "title": "Acute Severe Aortic Regurgitation Immediately After Cardiopulmonary Bypass Initiation in a Patient With a Bicuspid Aortic Valve.",
   "journal": "Cureus",
   "types": [
    "Case Reports",
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42860230",
   "title": "Jiawei Dingzhi Wan ameliorates chronic cerebral hypoperfusion-induced vascular cognitive impairment by modulating ACER2 and S1P-mediated microvascular angiogenesis and aortic vasoconstriction.",
   "journal": "J Ethnopharmacol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42860793",
   "title": "Thoracic endovascular aortic repair in hyperacute type B aortic dissection: a mini review.",
   "journal": "J Yeungnam Med Sci",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42860936",
   "title": "Rethinking circulatory management in thoracoabdominal aortic repair: split-body perfusion for continuous end-organ flow.",
   "journal": "J Vis Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42861042",
   "title": "Real-time three-dimensional echocardiographic assessment of the association between aortic diameter and left ventricular mechanical dyssynchrony in patients with bicuspid aortic valve.",
   "journal": "Quant Imaging Med Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42861074",
   "title": "Performance and incremental value of preoperative multimodal imaging and perioperative clinical characteristics in predicting postoperative major adverse events in type A aortic dissection.",
   "journal": "Quant Imaging Med Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42861142",
   "title": "Echocardiographic characteristics and clinical features of cardiac involvement in Behçet's disease: a retrospective single-center case series.",
   "journal": "Quant Imaging Med Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42861241",
   "title": "Meta-analysis of the histopathological features of surgically removed aortas classified according to the SCVP and AECVP consensus documents.",
   "journal": "Am Heart J Plus",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42861284",
   "title": "Mouse Models of Aortic Pathologies: Deciphering Molecular and Cellular Mechanisms from Bench to Bedside.",
   "journal": "CJC Open",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42861363",
   "title": "Towards a regional and national cardiothoracic biobank in India: translating a Dutch model to address a poorly characterised disease burden.",
   "journal": "Lancet Reg Health Southeast Asia",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42862070",
   "title": "Anticoagulation after transcatheter and surgical bioprosthetic aortic valve replacement: A narrative review.",
   "journal": "Perfusion",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42862110",
   "title": "Labetalol-induced hyperkalemia in acute aortic dissection: A rare but clinically relevant adverse effect.",
   "journal": "Am J Health Syst Pharm",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42862301",
   "title": "The Importance of Family Centered Care and Cascade Screening in Patients with Heritable Thoracic Aortic Aneurysm Disease.",
   "journal": "Pediatr Cardiol",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42862682",
   "title": "Bentall Procedure in a Patient with Loeys-Dietz Syndrome: A Case Report.",
   "journal": "Ann Card Anaesth",
   "types": [
    "Journal Article",
    "Case Reports"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42862939",
   "title": "Updated systematic review and meta-analysis comparing Myval versus Sapien 3 transcatheter heart valves in severe aortic stenosis: focus on early and one-year mortality.",
   "journal": "Acta Cardiol",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42863075",
   "title": "Heterochronicity shapes brain network formation.",
   "journal": "Proc Natl Acad Sci U S A",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42863733",
   "title": "1-Year Outcomes of Endovascular Repair of Zone 0/1 Aortic Arch Lesions with a Thoracic Branched Endoprosthesis.",
   "journal": "Ann Thorac Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42864670",
   "title": "Preoperative levels of biomarkers of coagulation to predict massive bleeding after surgical repair for acute type A aortic dissection: a retrospective cohort study.",
   "journal": "J Cardiothorac Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42865140",
   "title": "From maturation to degeneration: Distinct biological trajectories in bicuspid and tricuspid aortopathy.",
   "journal": "Exp Physiol",
   "types": [
    "Journal Article",
    "Review"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42866921",
   "title": "Guideline directed medical therapy and decongestion in patients with acute heart failure.",
   "journal": "Eur J Heart Fail",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42866932",
   "title": "RETRACTION: C/EBPα-Mediated Transcriptional Activation of PIK3C2A Regulates Autophagy, Matrix Metalloproteinase Expression, and Phenotypic of Vascular Smooth Muscle Cells in Aortic Dissection.",
   "journal": "J Immunol Res",
   "types": [
    "Journal Article",
    "Retraction Notice"
   ],
   "retraction_links": [
    [
     "RetractionOf",
     "36132983"
    ]
   ]
  },
  {
   "pmid": "42868953",
   "title": "Predicting acute kidney injury in type B aortic dissection: development and validation of a clinical nomogram.",
   "journal": "Clinics (Sao Paulo)",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42869089",
   "title": "Preoperative Risk-assessment Score for Elective Total Aortic Arch Repair: AAORTA Risk Tool.",
   "journal": "Aorta (Stamford)",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  },
  {
   "pmid": "42869527",
   "title": "Volume matters in type B aortic dissection-But why? What lies beyond the numbers.",
   "journal": "J Vasc Surg",
   "types": [
    "Journal Article"
   ],
   "retraction_links": []
  }
 ],
 "retained_records": {
  "42818172": {
   "selection": "bibliography; OQ-6",
   "doi": "10.64898/2026.09.16.26363254",
   "pmc": "PMC13622307",
   "title": "Gene-Based Rare Variant Burden Analyses Across Biobanks Identify Novel High-Risk Genes for Thoracic Aortic Disease.",
   "journal": "medRxiv",
   "types": [
    "Journal Article",
    "Preprint"
   ],
   "entrez": [
    "2026",
    "10",
    "1"
   ],
   "crossref_updated_by": []
  },
  "42818859": {
   "selection": "bibliography; OQ-6",
   "doi": "10.64898/2026.09.04.26362279",
   "pmc": "PMC13622748",
   "title": "Thoracic Aortic Disease in Genetic Syndromes Beyond Established Aortopathy Genes.",
   "journal": "medRxiv",
   "types": [
    "Journal Article",
    "Preprint"
   ],
   "entrez": [
    "2026",
    "10",
    "1"
   ],
   "crossref_updated_by": []
  },
  "42829835": {
   "selection": "bibliography; OQ-6",
   "doi": "10.1016/j.gim.2026.102741",
   "pmc": null,
   "title": "Loss of function variants in ADAMTS6: a new connective tissue disorder with heart defect, aortic aneurysm and neurodevelopmental features.",
   "journal": "Genet Med",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "4"
   ],
   "crossref_updated_by": []
  },
  "42839658": {
   "selection": "registry #29; bibliography",
   "doi": "10.1093/ejcts/ezag182",
   "pmc": null,
   "title": "EACTS Expert Consensus Document on aortic valve repair and valve-sparing aortic root replacement procedures.",
   "journal": "Eur J Cardiothorac Surg",
   "types": [
    "Consensus Statement",
    "Journal Article",
    "Systematic Review"
   ],
   "entrez": [
    "2026",
    "10",
    "7"
   ],
   "crossref_updated_by": []
  },
  "42839659": {
   "selection": "registry #30; bibliography",
   "doi": "10.1093/ejcts/ezag221",
   "pmc": null,
   "title": "EACTS Expert Consensus Document on Iatrogenic Aortic Dissection.",
   "journal": "Eur J Cardiothorac Surg",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "7"
   ],
   "crossref_updated_by": []
  },
  "42839649": {
   "selection": "registry #31; bibliography",
   "doi": "10.1093/icvts/ivag217",
   "pmc": "PMC13642968",
   "title": "EACTS Expert Consensus Document on Civil Aviation Following Cardiothoracic Surgery and Transcatheter Procedures.",
   "journal": "Interdiscip Cardiovasc Thorac Surg",
   "types": [
    "Journal Article",
    "Consensus Statement",
    "Review"
   ],
   "entrez": [
    "2026",
    "10",
    "7"
   ],
   "crossref_updated_by": []
  },
  "42849511": {
   "selection": "bibliography only",
   "doi": "10.1055/a-2965-6400",
   "pmc": "PMC13657142",
   "title": "Marfan Syndrome versus Loeys-Dietz Syndrome after Aortic Surgery: A Systematic Review and Meta-analysis of Reconstructed Time-to-Event Data.",
   "journal": "Aorta (Stamford)",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "8"
   ],
   "crossref_updated_by": []
  },
  "42850148": {
   "selection": "bibliography; statistics",
   "doi": "10.1016/j.jsams.2026.09.018",
   "pmc": null,
   "title": "Prevalence and determinants of thoracic aortic dilatation detected by focused cardiac ultrasound in recreational and competitive sport participants.",
   "journal": "J Sci Med Sport",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "8"
   ],
   "crossref_updated_by": []
  },
  "42863733": {
   "selection": "bibliography; surgical-and-endovascular-repair; clinical-trials-landscape",
   "doi": "10.1016/j.athoracsur.2026.09.050",
   "pmc": null,
   "title": "1-Year Outcomes of Endovascular Repair of Zone 0/1 Aortic Arch Lesions with a Thoracic Branched Endoprosthesis.",
   "journal": "Ann Thorac Surg",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "12"
   ],
   "crossref_updated_by": []
  },
  "42862301": {
   "selection": "bibliography; statistics; OQ-30",
   "doi": "10.1007/s00246-026-04501-y",
   "pmc": null,
   "title": "The Importance of Family Centered Care and Cascade Screening in Patients with Heritable Thoracic Aortic Aneurysm Disease.",
   "journal": "Pediatr Cardiol",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "12"
   ],
   "crossref_updated_by": []
  },
  "42822608": {
   "selection": "bibliography only",
   "doi": "10.1016/j.jvs.2026.08.044",
   "pmc": null,
   "title": "Selective Endovascular Aortic Repair in Connective Tissue Disease Patients Within a Multidisciplinary Program Achieves Comparable Outcomes in High-Risk Patients.",
   "journal": "J Vasc Surg",
   "types": [
    "Journal Article"
   ],
   "entrez": [
    "2026",
    "10",
    "1"
   ],
   "crossref_updated_by": []
  }
 },
 "retained_doi_only": [
  {
   "doi": "10.64898/2026.10.02.26364570",
   "source": "Europe PMC (PPR), Crossref posted-content (openRxiv/medRxiv), updated-by: none",
   "selection": "bibliography; medical-therapy; OQ-41",
   "title": "Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta"
  }
 ],
 "retraction_notice_screened": {
  "pmid": "42866932",
  "retracts": "36132983",
  "note": "Retraction notice for an aortic-dissection VSMC paper; PMID 36132983 is not cited anywhere in this condition (grep 2026-10-14)."
 },
 "cochrane": {
  "query": "\"Cochrane Database Syst Rev\"[jour] AND (aort* OR Marfan OR aneurysm*)",
  "result": "0 records in primary window, 0 in pdat window, 0 in gap window; cochranelibrary.com and CENTRAL not reachable (HTTP 403 per SOURCES.md) and not searched"
 },
 "europe_pmc": {
  "thoracic_core": {
   "query": "(\"thoracic aortic aneurysm\" OR \"ascending aortic aneurysm\" OR \"aortic root aneurysm\" OR \"heritable thoracic aortic\" OR \"thoracic aortic disease\" OR aortopathy) AND FIRST_PDATE:[2026-10-01 TO 2026-10-14]",
   "hitCount": 11,
   "records": [
    {
     "id": "42829835",
     "source": "MED",
     "pmid": "42829835",
     "doi": "10.1016/j.gim.2026.102741",
     "title": "Loss of function variants in ADAMTS6: a new connective tissue disorder with heart defect, aortic aneurysm and neurodevelopmental features.",
     "journal": "Genet Med",
     "pubType": "journal article",
     "date": "2026-10-03"
    },
    {
     "id": "PPR1332956",
     "source": "PPR",
     "pmid": null,
     "doi": "10.64898/2026.10.01.755974",
     "title": "Associations of age, sex, and bicuspid aortic valve with biaxial mechanical properties and circumferential residual stress in ascending thoracic aortic aneurysm",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-02"
    },
    {
     "id": "PPR1334369",
     "source": "PPR",
     "pmid": null,
     "doi": "10.64898/2026.10.02.26364570",
     "title": "Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-05"
    },
    {
     "id": "42690965",
     "source": "MED",
     "pmid": "42690965",
     "doi": "10.1148/rg.260012",
     "title": "Lung Cancer Screening: Beyond Pulmonary Nodules.",
     "journal": "Radiographics",
     "pubType": "review; journal article",
     "date": "2026-10-01"
    },
    {
     "id": "PPR1332708",
     "source": "PPR",
     "pmid": null,
     "doi": "10.20944/preprints202610.0126.v1",
     "title": "The Impact of Two <em>TNXB</em> Variants on the Development of Arterial Aneurysms, Dissection, and Bicuspid Aortic Valve",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-02"
    },
    {
     "id": "42825862",
     "source": "MED",
     "pmid": "42825862",
     "doi": "10.1007/s10557-026-07971-7",
     "title": "Allopurinol for Marfan Aortopathy: Pharmacogenomic Safety and Sex-Stratified Trial Design Warrant Consideration.",
     "journal": "Cardiovasc Drugs Ther",
     "pubType": "letter",
     "date": "2026-10-02"
    },
    {
     "id": "42822608",
     "source": "MED",
     "pmid": "42822608",
     "doi": "10.1016/j.jvs.2026.08.044",
     "title": "Selective Endovascular Aortic Repair in Connective Tissue Disease Patients Within a Multidisciplinary Program Achieves Comparable Outcomes in High-Risk Patients.",
     "journal": "J Vasc Surg",
     "pubType": "journal article",
     "date": "2026-10-01"
    },
    {
     "id": "42817891",
     "source": "MED",
     "pmid": "42817891",
     "doi": "10.1161/circimaging.126.019448",
     "title": "Optimal Patient Selection for Aortic Valve and Concomitant Ascending Aortic Procedures: Role of Multimodality Imaging.",
     "journal": "Circ Cardiovasc Imaging",
     "pubType": "review; journal article",
     "date": "2026-10-01"
    },
    {
     "id": "42828471",
     "source": "MED",
     "pmid": "42828471",
     "doi": "10.1002/clc.70482",
     "title": "From Genomics to Precision Cardiology: A Comprehensive Review of Clinical Applications and Challenges in Cardiovascular Diseases.",
     "journal": "Clin Cardiol",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-01"
    },
    {
     "id": "PMC13650666",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "The association between collagenopathies and the risk of spontaneous preterm birth: A systematic review with selective meta‐analysis",
     "journal": "Acta Obstet Gynecol Scand",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "PMC13648683",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Sequencing for a Lifetime: Professional Perspectives on the Value and Feasibility of Lifelong Genomic Medicine",
     "journal": "medRxiv",
     "pubType": "research-article; journal article",
     "date": "2026-10-03"
    }
   ]
  },
  "dissection": {
   "query": "\"aortic dissection\" AND FIRST_PDATE:[2026-10-01 TO 2026-10-14]",
   "hitCount": 20,
   "records": [
    {
     "id": "PPR1338627",
     "source": "PPR",
     "pmid": null,
     "doi": "10.21203/rs.3.rs-10540830/v1",
     "title": "A Prediction Model for In-Hospital Sternal Wound Complications After Aortic Dissection Surgery Based on Rewarming Time, Drainage Output, and Hemoglobin: A Retrospective Study",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-11"
    },
    {
     "id": "42829984",
     "source": "MED",
     "pmid": "42829984",
     "doi": "10.1002/nop2.70888",
     "title": "Readiness for Hospital Discharge and Quality of Life Among Patients Undergoing Surgery for Type A Aortic Dissection: A Prospective Observational Cohort Study. ",
     "journal": "Nurs Open",
     "pubType": "im; research-article; journal article; observational study",
     "date": "2026-10-01"
    },
    {
     "id": "PPR1332027",
     "source": "PPR",
     "pmid": null,
     "doi": "10.21203/rs.3.rs-10908505/v1",
     "title": "Exploration of N7-methylguanosine and immune-related biomarkers in Acute Aortic Dissection by combining bulk RNA-seq sequencing data and single-cell RNA sequencing",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-01"
    },
    {
     "id": "PPR1335576",
     "source": "PPR",
     "pmid": null,
     "doi": "10.21203/rs.3.rs-10507266/v1",
     "title": "Vacuum-Assisted Venous Drainage Combined with Modified Femoro-Femoral Partial Bypass for Spinal Cord Protection in Redo Thoracoabdominal Aneurysm Repair: A Historical Cohort Study",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-07"
    },
    {
     "id": "42716587",
     "source": "MED",
     "pmid": "42716587",
     "doi": "10.1016/j.jvs.2026.03.795",
     "title": "Letter regarding \"Impact of fragmented care on outcomes in the management of uncomplicated type B aortic dissection\".",
     "journal": "J Vasc Surg",
     "pubType": "letter",
     "date": "2026-10-01"
    },
    {
     "id": "42822618",
     "source": "MED",
     "pmid": "42822618",
     "doi": "10.1016/j.athoracsur.2026.08.029",
     "title": "Surgery for Acute Type A Aortic Dissection on Preoperative Anticoagulants and Antiplatelet Agents.",
     "journal": "Ann Thorac Surg",
     "pubType": "journal article",
     "date": "2026-10-01"
    },
    {
     "id": "42828522",
     "source": "MED",
     "pmid": "42828522",
     "doi": "10.1016/j.jaccas.2026.110570",
     "title": "Iatrogenic Crescentic Hematoma of the Right Sinus of Valsalva: A Diagnostic Pitfall Mimicking Aortic Root Dissection.",
     "journal": "JACC Case Rep",
     "pubType": "journal article; case reports",
     "date": "2026-10-03"
    },
    {
     "id": "PMC13650532",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Delayed diagnosis of selected thoracic and mediastinal conditions in young adults: a focused narrative review of clinical pitfalls, cognitive biases, and system barriers",
     "journal": "Front Med (Lausanne)",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-10"
    },
    {
     "id": "42830829",
     "source": "MED",
     "pmid": "42830829",
     "doi": "10.1093/jscr/rjag887",
     "title": "Type III endoleaks following endovascular aortic repair: a case series. ",
     "journal": "J Surg Case Rep",
     "pubType": "journal article; case reports; case-report",
     "date": "2026-10-04"
    },
    {
     "id": "PMC13643588",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "When an Extra X Means Extra Risk: Venous Thromboembolism in Klinefelter Syndrome",
     "journal": "Cureus",
     "pubType": "case reports; case-report",
     "date": "2026-10-08"
    },
    {
     "id": "PMC13650026",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Lactate Signal: Modulator of Cellular Energy Production and Anabolism",
     "journal": "Advanced science",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-08"
    },
    {
     "id": "PMC13649965",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Case Report: Recurrent peptic ulcer perforations—a possible role of median arcuate ligament syndrome",
     "journal": "Front Surg",
     "pubType": "case reports; case-report",
     "date": "2026-10-10"
    },
    {
     "id": "PMC13638428",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Multimodal neuromonitoring-guided cerebral protection and early neurocognitive outcomes after aortic arch surgery",
     "journal": "Front Physiol",
     "pubType": "research-article; journal article",
     "date": "2026-10-07"
    },
    {
     "id": "42827255",
     "source": "MED",
     "pmid": "42827255",
     "doi": "10.1186/s44215-026-00277-y",
     "title": "Inferior vena cava hyperechoic structure in a patient with cardiac myxoma: a surgical case report and literature review.",
     "journal": "Gen Thorac Cardiovasc Surg Cases",
     "pubType": "journal article; case-report",
     "date": "2026-10-02"
    },
    {
     "id": "PMC13649461",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Genomic convergence of mobilome-associated multidrug resistance and host-adaptation determinants in a postoperative Raoultella ornithinolytica isolate carrying blaKPC-2, blaNDM-5, and a truncated mcr-10-like element",
     "journal": "Front Cell Infect Microbiol",
     "pubType": "research-article; journal article",
     "date": "2026-10-10"
    },
    {
     "id": "PMC13643580",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Classification of Emergency Diagnosis–Sensitive Conditions Among Medicare Beneficiaries",
     "journal": "JAMA Netw Open",
     "pubType": "research-article; journal article",
     "date": "2026-10-01"
    },
    {
     "id": "PMC13646506",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Iatrogenic coronary artery dissection: detection, management, and prevention",
     "journal": "Front Cardiovasc Med",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "PMC13646072",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Associations of preoperative pan-immune inflammation value with postoperative acute kidney injury following open-heart surgery: a retrospective analysis",
     "journal": "Front Cardiovasc Med",
     "pubType": "research-article; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "PMC13649544",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Prognostic Impact of In-Hospital Emergency in Patients Admitted for Non-Surgical Intensive Care",
     "journal": "Circ Rep",
     "pubType": "research-article; journal article",
     "date": "2026-10-10"
    },
    {
     "id": "42827246",
     "source": "MED",
     "pmid": "42827246",
     "doi": "10.1186/s12889-026-29630-0",
     "title": "Six anthropometric indicators and their associations with myocardial infarction and death in Swedish automotive industry male workers followed for 28 years.",
     "journal": "BMC Public Health",
     "pubType": "research-article; journal article",
     "date": "2026-10-02"
    }
   ]
  },
  "syndromes": {
   "query": "(Marfan OR \"Loeys-Dietz\" OR \"vascular Ehlers-Danlos\") AND (aort*) AND FIRST_PDATE:[2026-10-01 TO 2026-10-14]",
   "hitCount": 6,
   "records": [
    {
     "id": "42822608",
     "source": "MED",
     "pmid": "42822608",
     "doi": "10.1016/j.jvs.2026.08.044",
     "title": "Selective Endovascular Aortic Repair in Connective Tissue Disease Patients Within a Multidisciplinary Program Achieves Comparable Outcomes in High-Risk Patients.",
     "journal": "J Vasc Surg",
     "pubType": "journal article",
     "date": "2026-10-01"
    },
    {
     "id": "42829835",
     "source": "MED",
     "pmid": "42829835",
     "doi": "10.1016/j.gim.2026.102741",
     "title": "Loss of function variants in ADAMTS6: a new connective tissue disorder with heart defect, aortic aneurysm and neurodevelopmental features.",
     "journal": "Genet Med",
     "pubType": "journal article",
     "date": "2026-10-03"
    },
    {
     "id": "PMC13650666",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "The association between collagenopathies and the risk of spontaneous preterm birth: A systematic review with selective meta‐analysis",
     "journal": "Acta Obstet Gynecol Scand",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "42828471",
     "source": "MED",
     "pmid": "42828471",
     "doi": "10.1002/clc.70482",
     "title": "From Genomics to Precision Cardiology: A Comprehensive Review of Clinical Applications and Challenges in Cardiovascular Diseases.",
     "journal": "Clin Cardiol",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-01"
    },
    {
     "id": "42825862",
     "source": "MED",
     "pmid": "42825862",
     "doi": "10.1007/s10557-026-07971-7",
     "title": "Allopurinol for Marfan Aortopathy: Pharmacogenomic Safety and Sex-Stratified Trial Design Warrant Consideration.",
     "journal": "Cardiovasc Drugs Ther",
     "pubType": "letter",
     "date": "2026-10-02"
    },
    {
     "id": "PMC13640610",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Integrated microarray-based and single-cell transcriptomic analyses reveal cell adhesion-related fibrotic remodeling signatures in heart failure",
     "journal": "Front Mol Biosci",
     "pubType": "research-article; journal article",
     "date": "2026-10-07"
    }
   ]
  },
  "non_medline_only": {
   "query": "(\"thoracic aortic aneurysm\" OR \"aortic dissection\" OR aortopathy OR Marfan) AND FIRST_PDATE:[2026-10-01 TO 2026-10-14] NOT SRC:MED",
   "hitCount": 23,
   "records": [
    {
     "id": "PPR1332956",
     "source": "PPR",
     "pmid": null,
     "doi": "10.64898/2026.10.01.755974",
     "title": "Associations of age, sex, and bicuspid aortic valve with biaxial mechanical properties and circumferential residual stress in ascending thoracic aortic aneurysm",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-02"
    },
    {
     "id": "PPR1334369",
     "source": "PPR",
     "pmid": null,
     "doi": "10.64898/2026.10.02.26364570",
     "title": "Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-05"
    },
    {
     "id": "PMC13650666",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "The association between collagenopathies and the risk of spontaneous preterm birth: A systematic review with selective meta‐analysis",
     "journal": "Acta Obstet Gynecol Scand",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "PPR1332708",
     "source": "PPR",
     "pmid": null,
     "doi": "10.20944/preprints202610.0126.v1",
     "title": "The Impact of Two <em>TNXB</em> Variants on the Development of Arterial Aneurysms, Dissection, and Bicuspid Aortic Valve",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-02"
    },
    {
     "id": "PPR1338627",
     "source": "PPR",
     "pmid": null,
     "doi": "10.21203/rs.3.rs-10540830/v1",
     "title": "A Prediction Model for In-Hospital Sternal Wound Complications After Aortic Dissection Surgery Based on Rewarming Time, Drainage Output, and Hemoglobin: A Retrospective Study",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-11"
    },
    {
     "id": "PPR1332027",
     "source": "PPR",
     "pmid": null,
     "doi": "10.21203/rs.3.rs-10908505/v1",
     "title": "Exploration of N7-methylguanosine and immune-related biomarkers in Acute Aortic Dissection by combining bulk RNA-seq sequencing data and single-cell RNA sequencing",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-01"
    },
    {
     "id": "PPR1335576",
     "source": "PPR",
     "pmid": null,
     "doi": "10.21203/rs.3.rs-10507266/v1",
     "title": "Vacuum-Assisted Venous Drainage Combined with Modified Femoro-Femoral Partial Bypass for Spinal Cord Protection in Redo Thoracoabdominal Aneurysm Repair: A Historical Cohort Study",
     "journal": null,
     "pubType": "preprint",
     "date": "2026-10-07"
    },
    {
     "id": "PMC13648160",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Conduction Gap of Left Atrial Anterior Wall Linear Ablation Undetected by Left Atrial Appendage Pacing but Revealed by Left Lateral Ridge Pacing",
     "journal": "J Arrhythm",
     "pubType": "brief-report; brief report",
     "date": "2026-10-01"
    },
    {
     "id": "PMC13650532",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Delayed diagnosis of selected thoracic and mediastinal conditions in young adults: a focused narrative review of clinical pitfalls, cognitive biases, and system barriers",
     "journal": "Front Med (Lausanne)",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-10"
    },
    {
     "id": "PMC13643588",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "When an Extra X Means Extra Risk: Venous Thromboembolism in Klinefelter Syndrome",
     "journal": "Cureus",
     "pubType": "case reports; case-report",
     "date": "2026-10-08"
    },
    {
     "id": "PMC13650026",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Lactate Signal: Modulator of Cellular Energy Production and Anabolism",
     "journal": "Advanced science",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-08"
    },
    {
     "id": "PMC13649965",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Case Report: Recurrent peptic ulcer perforations—a possible role of median arcuate ligament syndrome",
     "journal": "Front Surg",
     "pubType": "case reports; case-report",
     "date": "2026-10-10"
    },
    {
     "id": "PMC13638428",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Multimodal neuromonitoring-guided cerebral protection and early neurocognitive outcomes after aortic arch surgery",
     "journal": "Front Physiol",
     "pubType": "research-article; journal article",
     "date": "2026-10-07"
    },
    {
     "id": "PMC13649461",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Genomic convergence of mobilome-associated multidrug resistance and host-adaptation determinants in a postoperative Raoultella ornithinolytica isolate carrying blaKPC-2, blaNDM-5, and a truncated mcr-10-like element",
     "journal": "Front Cell Infect Microbiol",
     "pubType": "research-article; journal article",
     "date": "2026-10-10"
    },
    {
     "id": "PMC13643580",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Classification of Emergency Diagnosis–Sensitive Conditions Among Medicare Beneficiaries",
     "journal": "JAMA Netw Open",
     "pubType": "research-article; journal article",
     "date": "2026-10-01"
    },
    {
     "id": "PMC13638604",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Routine baseline clinical data do not reliably predict poor first-year myopia control with low-dose atropine: a machine-learning benchmarking study",
     "journal": "Front Ophthalmol (Lausanne)",
     "pubType": "brief-report; brief report",
     "date": "2026-10-07"
    },
    {
     "id": "PMC13646506",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Iatrogenic coronary artery dissection: detection, management, and prevention",
     "journal": "Front Cardiovasc Med",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "PMC13646072",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Associations of preoperative pan-immune inflammation value with postoperative acute kidney injury following open-heart surgery: a retrospective analysis",
     "journal": "Front Cardiovasc Med",
     "pubType": "research-article; journal article",
     "date": "2026-10-09"
    },
    {
     "id": "PMC13640610",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Integrated microarray-based and single-cell transcriptomic analyses reveal cell adhesion-related fibrotic remodeling signatures in heart failure",
     "journal": "Front Mol Biosci",
     "pubType": "research-article; journal article",
     "date": "2026-10-07"
    },
    {
     "id": "PMC13649544",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Prognostic Impact of In-Hospital Emergency in Patients Admitted for Non-Surgical Intensive Care",
     "journal": "Circ Rep",
     "pubType": "research-article; journal article",
     "date": "2026-10-10"
    },
    {
     "id": "PMC13648683",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Sequencing for a Lifetime: Professional Perspectives on the Value and Feasibility of Lifelong Genomic Medicine",
     "journal": "medRxiv",
     "pubType": "research-article; journal article",
     "date": "2026-10-03"
    },
    {
     "id": "PMC13634963",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "Condition-specific mediolateral sway and task-dependent postural complexity in individuals with generalized joint hypermobility",
     "journal": "Front Bioeng Biotechnol",
     "pubType": "research-article; journal article",
     "date": "2026-10-06"
    },
    {
     "id": "PMC13632478",
     "source": "PMC",
     "pmid": null,
     "doi": null,
     "title": "From chromatin to proteostasis: multilevel gene regulation in Mendelian diseases",
     "journal": "Front Epigenet Epigenom",
     "pubType": "review-article; review; journal article",
     "date": "2026-10-07"
    }
   ]
  }
 },
 "clinicaltrials_endpoint_template": "https://clinicaltrials.gov/api/v2/studies/{NCT_ID}",
 "tracked_trial_count": 52,
 "trials": [
  {
   "id": "NCT00126204",
   "status": "COMPLETED",
   "last_update": {
    "date": "2010-03-04",
    "type": "ESTIMATED"
   },
   "primary_completion": null,
   "completion": {
    "date": "2006-07"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 75
   }
  },
  {
   "id": "NCT00429364",
   "status": "COMPLETED",
   "last_update": {
    "date": "2025-03-07",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2014-02",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2014-02",
    "type": "ACTUAL"
   },
   "results": true,
   "results_posted": {
    "date": "2015-04-01",
    "type": "ESTIMATED"
   },
   "enrollment": {
    "count": 608,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT00485368",
   "status": "COMPLETED",
   "last_update": {
    "date": "2007-06-13",
    "type": "ESTIMATED"
   },
   "primary_completion": null,
   "completion": {
    "date": "2006-09",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 17,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT00538967",
   "status": "COMPLETED",
   "last_update": {
    "date": "2007-10-03",
    "type": "ESTIMATED"
   },
   "primary_completion": null,
   "completion": {
    "date": "2005-08",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 60,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT00593710",
   "status": "COMPLETED",
   "last_update": {
    "date": "2012-07-12",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2010-10",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2011-12",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 17,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT00683124",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2011-07-22",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2013-07",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2013-07",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 291,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT00723801",
   "status": "COMPLETED",
   "last_update": {
    "date": "2014-09-09",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2012-12",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2012-12",
    "type": "ACTUAL"
   },
   "results": true,
   "results_posted": {
    "date": "2014-09-01",
    "type": "ESTIMATED"
   },
   "enrollment": {
    "count": 40,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT00763893",
   "status": "TERMINATED",
   "last_update": {
    "date": "2015-11-04",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2014-01",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2014-12",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 303,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT00782327",
   "status": "COMPLETED",
   "last_update": {
    "date": "2022-12-22",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2014-11-26",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2014-11-26",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 22,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01145612",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2010-08-12",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2013-02",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2013-02",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 140,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01295047",
   "status": "COMPLETED",
   "last_update": {
    "date": "2011-02-14",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2007-12",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2008-12",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 18,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01361087",
   "status": "WITHDRAWN",
   "last_update": {
    "date": "2016-02-05",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2014-12",
    "type": "ACTUAL"
   },
   "completion": null,
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 0,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01415804",
   "status": "COMPLETED",
   "last_update": {
    "date": "2011-08-12",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2010-10",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2011-03",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 140,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01715207",
   "status": "COMPLETED",
   "last_update": {
    "date": "2017-06-05",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2014-10",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2014-12",
    "type": "ACTUAL"
   },
   "results": true,
   "results_posted": {
    "date": "2017-05-04",
    "type": "ACTUAL"
   },
   "enrollment": {
    "count": 30,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01756833",
   "status": "COMPLETED",
   "last_update": {
    "date": "2021-11-26",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2019-07-23",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2019-07-23",
    "type": "ACTUAL"
   },
   "results": true,
   "results_posted": {
    "date": "2021-11-26",
    "type": "ACTUAL"
   },
   "enrollment": {
    "count": 261,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT01949233",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2015-06-09",
    "type": "ESTIMATED"
   },
   "primary_completion": {
    "date": "2015-10",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2017-12",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 56,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT02086136",
   "status": "COMPLETED",
   "last_update": {
    "date": "2019-01-03",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2016-12",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2016-12",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 1900,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT02201589",
   "status": "RECRUITING",
   "last_update": {
    "date": "2025-05-06",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2028-12",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2033-12",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 20,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT02256163",
   "status": "COMPLETED",
   "last_update": {
    "date": "2017-11-20",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2016-12",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2017-03",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 258,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT02299947",
   "status": "TERMINATED",
   "last_update": {
    "date": "2019-05-10",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2018-04-26",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2018-04-26",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 27,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT02538822",
   "status": "TERMINATED",
   "last_update": {
    "date": "2023-05-24",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2018-09-16",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2018-09-16",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 31,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT02724072",
   "status": "COMPLETED",
   "last_update": {
    "date": "2022-05-16",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2019-06-24",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2021-07-30",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 84,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT03090763",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2017-03-27",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2018-05-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2019-06-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 200,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT03142074",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2024-07-01",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2025-12",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2025-12",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 180,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT03214601",
   "status": "ACTIVE_NOT_RECRUITING",
   "last_update": {
    "date": "2025-05-31",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2023-09-18",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2028-08-31",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 30,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT03322033",
   "status": "TERMINATED",
   "last_update": {
    "date": "2026-03-02",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2021-10-22",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2021-10-22",
    "type": "ACTUAL"
   },
   "results": true,
   "results_posted": {
    "date": "2026-03-02",
    "type": "ACTUAL"
   },
   "enrollment": {
    "count": 1,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT03410420",
   "status": "COMPLETED",
   "last_update": {
    "date": "2026-01-23",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2025-09-01",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2025-09-01",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 9,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT03440697",
   "status": "ACTIVE_NOT_RECRUITING",
   "last_update": {
    "date": "2026-02-13",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2030-12-31",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2030-12-31",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 3000,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT03507413",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2024-03-28",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2024-05-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2024-05-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 170,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT03536312",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-09-28",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2035-05-31",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2035-05-31",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 610,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT03861741",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2021-05-03",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2022-05-20",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2022-05-20",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 70,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT04197648",
   "status": "RECRUITING",
   "last_update": {
    "date": "2025-06-29",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2026-10",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2027-04",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 30,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT04224051",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2023-09-06",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2026-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2026-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 500,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT04381507",
   "status": "TERMINATED",
   "last_update": {
    "date": "2024-10-18",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2024-07-24",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2024-07-24",
    "type": "ACTUAL"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 1,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT04500756",
   "status": "RECRUITING",
   "last_update": {
    "date": "2025-04-18",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2028-06-30",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2028-06-30",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 314,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT04545502",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-08-20",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2028-08",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2037-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 2000,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT05174767",
   "status": "ACTIVE_NOT_RECRUITING",
   "last_update": {
    "date": "2025-01-15",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2023-12-11",
    "type": "ACTUAL"
   },
   "completion": {
    "date": "2029-12-06",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 115,
    "type": "ACTUAL"
   }
  },
  {
   "id": "NCT05215587",
   "status": "RECRUITING",
   "last_update": {
    "date": "2025-08-11",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2026-12-31",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2030-12-31",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 554,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT05361772",
   "status": "UNKNOWN",
   "last_update": {
    "date": "2022-05-05",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2024-06-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2025-12-31",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 230,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT05715203",
   "status": "RECRUITING",
   "last_update": {
    "date": "2025-09-10",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2025-11-30",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2025-12-31",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 250,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT05800743",
   "status": "ENROLLING_BY_INVITATION",
   "last_update": {
    "date": "2026-05-29",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2029-10",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2034-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 370,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06044259",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-09-30",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2027-09-30",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2028-09-30",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 72,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06280482",
   "status": "RECRUITING",
   "last_update": {
    "date": "2025-09-12",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2027-07-25",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2027-07-25",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 15,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06377033",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-08-14",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2027-06-30",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2027-06-30",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 1000,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06550986",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-03-23",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2027-02-15",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2029-02-15",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 30,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06740721",
   "status": "NOT_YET_RECRUITING",
   "last_update": {
    "date": "2026-01-29",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2027-01-04",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2029-01-03",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 15,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06783803",
   "status": "ACTIVE_NOT_RECRUITING",
   "last_update": {
    "date": "2025-01-20",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2029-05",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2029-06",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 20,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT06827990",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-08-11",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2030-09-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2031-09-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 112,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT07034430",
   "status": "ACTIVE_NOT_RECRUITING",
   "last_update": {
    "date": "2025-06-27",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2026-01-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2026-01-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 102,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT07205250",
   "status": "NOT_YET_RECRUITING",
   "last_update": {
    "date": "2026-02-12",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2028-01-20",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2028-09-20",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 224,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT07483177",
   "status": "RECRUITING",
   "last_update": {
    "date": "2026-06-08",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2028-05",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2028-05",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 50,
    "type": "ESTIMATED"
   }
  },
  {
   "id": "NCT07495267",
   "status": "NOT_YET_RECRUITING",
   "last_update": {
    "date": "2026-03-27",
    "type": "ACTUAL"
   },
   "primary_completion": {
    "date": "2028-03-01",
    "type": "ESTIMATED"
   },
   "completion": {
    "date": "2028-03-01",
    "type": "ESTIMATED"
   },
   "results": false,
   "results_posted": null,
   "enrollment": {
    "count": 15,
    "type": "ESTIMATED"
   }
  }
 ],
 "trial_changes_since_2026_09_30": "none: status, last-update date, completion dates, results flags and enrollment identical for all 52",
 "newly_cited_trials": [
  "NCT02777528 (GORE TBE Zone 0/1 pivotal; results posted 2025-06-25)",
  "NCT07166133 (TBE Zone 0/1 post-approval study)",
  "ISRCTN30838068 (EARNEST, ISRCTN API https://www.isrctn.com/api/query/format/default?q=%22aortic%20aneurysm%22%20OR%20%22aortic%20dissection%22%20OR%20Marfan; 121 records, 5 updated since 2026-09-30)"
 ],
 "ctgov_search": "query.term=Thoracic Branch Endoprosthesis (to map the Brinkman 2026 paper to its registration)",
 "web_sources_checked": {
  "https://www.marfan.org/news/": "200; October 3-7 listings (Barcelona scientific meeting, Spanish family symposium)",
  "https://www.aorticdissectionawareness.org/": "200; October 1-4 patient stories and safe-transfer feature",
  "https://www.eacts.org/resources/clinical-guidelines/": "200; no October-dated item found in static HTML",
  "https://www.escardio.org/Guidelines": "200; no new aortic guideline identified",
  "https://vascern.eu/groupe/heritable-thoracic-aortic-diseases/": "200; no October item extracted",
  "https://www.johnritterfoundation.org/": "200; no October item extracted",
  "https://www.marfantrust.org/news": "404",
  "https://www.thoracicaorticdisease.org/": "no response"
 },
 "not_queried": [
  "WHO ICTRP portal (JS-driven; ISRCTN queried directly instead)",
  "EudraCT/CTIS, ChiCTR, CTRI, JPRN",
  "Unpaywall (LIFEBANK_CONTACT_EMAIL unset)",
  "OpenAlex",
  "DOAJ",
  "SciELO/LILACS (HTTP 403)",
  "Cochrane Library/CENTRAL (HTTP 403)",
  "bioRxiv/medRxiv MCP tools (preprints covered via PubMed-indexed preprints and Europe PMC PPR source)"
 ]
}