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{
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"title": "A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH"
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"title": "Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment"
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"title": "Phase 3 Study to Evaluate the Efficacy and Safety of Elafibranor Versus Placebo in Patients With Nonalcoholic Steatohepatitis (NASH)"
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"title": "Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)"
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"title": "Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis."
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"title": "Phase 2b Study in NASH to Assess IVA337"
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"title": "Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis"
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"why_stopped": "This study was terminated early due to lack of efficacy based on the results of the Week 48 analysis as prespecified in the clinical study protocol.",
"title": "Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)"
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"title": "The Liver Health Study for Patients with NAFLD"
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"title": "Lanifibranor in Patients With Type 2 Diabetes & Nonalcoholic Fatty Liver Disease"
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"title": "Bariatric Surgery Versus Non-alcoholic Steato-hepatitis"
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"title": "Dapagliflozin Efficacy and Action in NASH"
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"title": "Intragastric Balloon in Compensated NASH(Non Alcoholic Steato Hepatitis) Cirrhotics"
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"title": "A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis"
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"title": "A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver Damage"
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"title": "A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects"
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"title": "A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH)"
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"title": "A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients"
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"title": "A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)"
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"title": "A Study of Efruxifermin in Non-Cirrhotic Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)"
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"title": "A Study to Test Safety and Efficacy of Survodutide (BI456906) in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)"
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"title": "Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)"
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"title": "Estrogen Administration for the Treatment of NASH in Postmenopausal Women"
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"title": "A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )"
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"title": "A Study of LY3437943 in Participants Who Have Obesity or Are Overweight"
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"title": "Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)"
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{
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"title": "Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH)"
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{
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"primary_completion_date": "2022-10-19",
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"title": "A Study of Efinopegdutide (MK-6024) in Participants With Nonalcoholic Fatty Liver Disease (NAFLD) (MK-6024-001)"
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{
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"title": "A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)"
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"title": "ALT-801 in Diabetic and Non-Diabetic Overweight and Obese Subjects With Non-alcoholic Fatty Liver Disease (NAFLD)"
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{
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"title": "A Study of Efruxifermin in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (Symmetry)"
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"title": "Study to Assess the Safety, Tolerability, and Pharmacokinetics (Movement of Drugs Within the Body) of AZD2693 in Healthy Participants"
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"title": "A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)"
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{
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"title": "A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition"
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{
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"title": "A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)"
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{
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"title": "A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis"
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{
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"title": "A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693"
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"primary_completion_date": "2026-03-03",
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"title": "A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)"
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"title": "To Evaluate the Efficacy and Safety of HSK31679 in Chinese Patients With Non-Alcoholic Steatohepatitis (NASH) ."
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"title": "A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis"
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"title": "A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)"
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"title": "A Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of VSA006 in Chinese NASH Patients"
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"title": "Fibrosis Lessens After Metabolic Surgery"
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"title": "A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH"
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"title": "A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis"
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"why_stopped": null,
"title": "A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH"
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"title": "A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis"
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"primary_completion_date": "2031-12-27",
"enrollment": 1800,
"why_stopped": null,
"title": "LIVERAGE\u2122: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis"
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"primary_completion_date": "2029-06-05",
"enrollment": 1590,
"why_stopped": null,
"title": "LIVERAGE\u2122 - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis"
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{
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"results_section_present": false,
"primary_completion_date": "2028-01-31",
"enrollment": 32,
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"title": "NAFLD Clinical Care Pathway"
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{
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"results_first_posted": null,
"results_section_present": false,
"primary_completion_date": "2026-12-31",
"enrollment": 479,
"why_stopped": null,
"title": "A Study Comparing IBI362 vs Semaglutide in Chinese Overweight or Obese Adults With Metabolic Dysfunction-associated Fatty Liver Disease \uff08MAFLD\uff09"
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{
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"primary_completion_date": "2029-02-01",
"enrollment": 70,
"why_stopped": null,
"title": "Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease"
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{
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"last_update_posted": "2026-10-08",
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"primary_completion_date": "2030-08",
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"title": "A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)"
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{
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"title": "A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH"
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{
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"enrollment": 1200,
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"title": "A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH"
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{
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"enrollment": 210,
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"title": "Using Hydroxychloroquine (HCQ) to Treat Steatohepatitis"
},
{
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"results_first_posted": null,
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"primary_completion_date": "2030-03-15",
"enrollment": 204,
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"title": "A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD"
},
{
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{
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"title": "A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)"
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"pubmed_pubtypes": [
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],
"crossref_updated_by": "ERR HTTP Error 404: Not Found"
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"42911297 patient-experience-and-advocacy.md",
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"limitations": [
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