{
 "condition": "irritable-bowel-syndrome",
 "sweep_date": "2026-10-28",
 "author_engine": "Claude",
 "independent_audit": "not performed; edited wiki pages are draft",
 "window": {
  "from": "2026-10-21",
  "through": "2026-10-28",
  "inclusive": true,
  "pubmed_fields": [
   "PDAT",
   "EDAT"
  ],
  "europe_pmc_fields": [
   "FIRST_PDATE",
   "FIRST_IDATE"
  ]
 },
 "method_notes": [
  "Topic query strings reused verbatim from the 2026-10-21 manifest with the date window replaced.",
  "PubMed MCP server was disconnected; all PubMed queries used E-utilities esearch/efetch directly.",
  "Europe PMC counts are screening hits including off-topic full-text matches, not distinct new IBS papers.",
  "A disk-full (ENOSPC) interruption occurred mid-session; no repository file had been written before it, and all writes followed recovery."
 ],
 "pubmed_topic_and_cochrane_searches": [
  {
   "topic": "overview",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "31",
   "idlist": [
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    "42943524",
    "42942808",
    "42942061",
    "42941862",
    "42940160",
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    "42936312",
    "42934967",
    "42934540",
    "42933944",
    "42928586",
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    "42924828",
    "42923306",
    "42919315",
    "42918357",
    "42918294",
    "42914364",
    "42910824",
    "42910145",
    "42909825",
    "42909342",
    "42908452",
    "42908445",
    "42906826",
    "42904019",
    "42903081",
    "42902396",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "overview",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "diagnosis-rome",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (Rome OR diagnos* OR criteria OR biomarker*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "16",
   "idlist": [
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    "42933944",
    "42928586",
    "42928090",
    "42927267",
    "42924828",
    "42919315",
    "42918294",
    "42910145",
    "42909342",
    "42904019",
    "42902396",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rome\"[MeSH Terms] OR \"rome\"[All Fields] OR \"diagnos*\"[All Fields] OR (\"criteria s\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[MeSH Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]) OR \"biomarker*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "diagnosis-rome",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (Rome OR diagnos* OR criteria OR biomarker*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rome\"[MeSH Terms] OR \"rome\"[All Fields] OR \"diagnos*\"[All Fields] OR (\"criteria s\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[MeSH Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]) OR \"biomarker*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "epidemiology-burden",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (prevalence OR incidence OR epidemiolog* OR mortality OR burden OR cost*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "11",
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    "42918357",
    "42918294",
    "42910824",
    "42909825",
    "42904019",
    "42902396",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR \"epidemiolog*\"[All Fields] OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR \"cost*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "epidemiology-burden",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (prevalence OR incidence OR epidemiolog* OR mortality OR burden OR cost*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR \"epidemiolog*\"[All Fields] OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR \"cost*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "differential-safety",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (differential OR celiac OR coeliac OR microscopic colitis OR bile acid OR alarm OR safety OR adverse OR suicid*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "15",
   "idlist": [
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    "42942061",
    "42941862",
    "42934540",
    "42928090",
    "42927267",
    "42918294",
    "42910145",
    "42909825",
    "42909342",
    "42908445",
    "42906826",
    "42904019",
    "42903081",
    "42902396"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"cell differentiation\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"differentiation\"[All Fields]) OR \"cell differentiation\"[All Fields] OR \"differentiated\"[All Fields] OR \"differentiation\"[All Fields] OR \"differential\"[All Fields] OR \"differentials\"[All Fields] OR \"differentiate\"[All Fields] OR \"differentiates\"[All Fields] OR \"differentiating\"[All Fields] OR \"differentiational\"[All Fields] OR \"differentiations\"[All Fields] OR \"differentiative\"[All Fields] OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"colitis, microscopic\"[MeSH Terms] OR (\"colitis\"[All Fields] AND \"microscopic\"[All Fields]) OR \"microscopic colitis\"[All Fields] OR (\"microscopic\"[All Fields] AND \"colitis\"[All Fields])) OR (\"bile acids and salts\"[Supplementary Concept] OR \"bile acids and salts\"[All Fields] OR \"bile acid\"[All Fields] OR \"bile acids and salts\"[MeSH Terms] OR (\"bile\"[All Fields] AND \"acids\"[All Fields] AND \"salts\"[All Fields]) OR (\"bile\"[All Fields] AND \"acid\"[All Fields])) OR (\"alarm\"[All Fields] OR \"alarm s\"[All Fields] OR \"alarmed\"[All Fields] OR \"alarming\"[All Fields] OR \"alarms\"[All Fields]) OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR (\"adverse\"[All Fields] OR \"adversely\"[All Fields] OR \"adverses\"[All Fields]) OR \"suicid*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "differential-safety",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (differential OR celiac OR coeliac OR microscopic colitis OR bile acid OR alarm OR safety OR adverse OR suicid*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"cell differentiation\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"differentiation\"[All Fields]) OR \"cell differentiation\"[All Fields] OR \"differentiated\"[All Fields] OR \"differentiation\"[All Fields] OR \"differential\"[All Fields] OR \"differentials\"[All Fields] OR \"differentiate\"[All Fields] OR \"differentiates\"[All Fields] OR \"differentiating\"[All Fields] OR \"differentiational\"[All Fields] OR \"differentiations\"[All Fields] OR \"differentiative\"[All Fields] OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"colitis, microscopic\"[MeSH Terms] OR (\"colitis\"[All Fields] AND \"microscopic\"[All Fields]) OR \"microscopic colitis\"[All Fields] OR (\"microscopic\"[All Fields] AND \"colitis\"[All Fields])) OR (\"bile acids and salts\"[Supplementary Concept] OR \"bile acids and salts\"[All Fields] OR \"bile acid\"[All Fields] OR \"bile acids and salts\"[MeSH Terms] OR (\"bile\"[All Fields] AND \"acids\"[All Fields] AND \"salts\"[All Fields]) OR (\"bile\"[All Fields] AND \"acid\"[All Fields])) OR (\"alarm\"[All Fields] OR \"alarm s\"[All Fields] OR \"alarmed\"[All Fields] OR \"alarming\"[All Fields] OR \"alarms\"[All Fields]) OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR (\"adverse\"[All Fields] OR \"adversely\"[All Fields] OR \"adverses\"[All Fields]) OR \"suicid*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "brain-gut",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (visceral OR hypersensitiv* OR brain OR neural OR genetic* OR enterochromaffin) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "19",
   "idlist": [
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    "42942061",
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    "42939282",
    "42936312",
    "42934967",
    "42933944",
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    "42918294",
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    "42909342",
    "42908452",
    "42908445",
    "42904019",
    "42902396",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"visceral\"[All Fields] OR \"viscerally\"[All Fields] OR \"hypersensitiv*\"[All Fields] OR (\"brain\"[MeSH Terms] OR \"brain\"[All Fields] OR \"brains\"[All Fields] OR \"brain s\"[All Fields]) OR (\"neural\"[All Fields] OR \"neuralization\"[All Fields] OR \"neuralize\"[All Fields] OR \"neuralized\"[All Fields] OR \"neuralizes\"[All Fields] OR \"neuralizing\"[All Fields] OR \"neurally\"[All Fields]) OR \"genetic*\"[All Fields] OR (\"enterochromaffin cells\"[MeSH Terms] OR (\"enterochromaffin\"[All Fields] AND \"cells\"[All Fields]) OR \"enterochromaffin cells\"[All Fields] OR \"enterochromaffin\"[All Fields] OR \"enterochromaffine\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "brain-gut",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (visceral OR hypersensitiv* OR brain OR neural OR genetic* OR enterochromaffin) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"visceral\"[All Fields] OR \"viscerally\"[All Fields] OR \"hypersensitiv*\"[All Fields] OR (\"brain\"[MeSH Terms] OR \"brain\"[All Fields] OR \"brains\"[All Fields] OR \"brain s\"[All Fields]) OR (\"neural\"[All Fields] OR \"neuralization\"[All Fields] OR \"neuralize\"[All Fields] OR \"neuralized\"[All Fields] OR \"neuralizes\"[All Fields] OR \"neuralizing\"[All Fields] OR \"neurally\"[All Fields]) OR \"genetic*\"[All Fields] OR (\"enterochromaffin cells\"[MeSH Terms] OR (\"enterochromaffin\"[All Fields] AND \"cells\"[All Fields]) OR \"enterochromaffin cells\"[All Fields] OR \"enterochromaffin\"[All Fields] OR \"enterochromaffine\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "microbiome",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (microbiom* OR microbiot* OR probiotic* OR fecal OR faecal OR FMT) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "16",
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    "42914364",
    "42910145",
    "42909342",
    "42908452",
    "42903081",
    "42902396",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"microbiom*\"[All Fields] OR \"microbiot*\"[All Fields] OR \"probiotic*\"[All Fields] OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"ferment technol\"[Journal] OR \"fmt\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "microbiome",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (microbiom* OR microbiot* OR probiotic* OR fecal OR faecal OR FMT) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"microbiom*\"[All Fields] OR \"microbiot*\"[All Fields] OR \"probiotic*\"[All Fields] OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"ferment technol\"[Journal] OR \"fmt\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "post-infectious",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (postinfect* OR post-infect* OR gastroenteritis OR COVID) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "1",
   "idlist": [
    "42941862"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"postinfect*\"[All Fields] OR \"post infect*\"[All Fields] OR (\"gastroenteric\"[All Fields] OR \"gastroenteritis\"[MeSH Terms] OR \"gastroenteritis\"[All Fields] OR \"gastroenteritides\"[All Fields]) OR (\"sars cov 2\"[MeSH Terms] OR \"sars cov 2\"[All Fields] OR \"covid\"[All Fields] OR \"covid 19\"[MeSH Terms] OR \"covid 19\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "post-infectious",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (postinfect* OR post-infect* OR gastroenteritis OR COVID) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"postinfect*\"[All Fields] OR \"post infect*\"[All Fields] OR (\"gastroenteric\"[All Fields] OR \"gastroenteritis\"[MeSH Terms] OR \"gastroenteritis\"[All Fields] OR \"gastroenteritides\"[All Fields]) OR (\"sars cov 2\"[MeSH Terms] OR \"sars cov 2\"[All Fields] OR \"covid\"[All Fields] OR \"covid 19\"[MeSH Terms] OR \"covid 19\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "diet",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diet* OR FODMAP OR fibre OR fiber OR gluten OR eating disorder*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "6",
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    "42943524",
    "42942061",
    "42933944",
    "42918294",
    "42903081",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diet*\"[All Fields] OR (\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"glutens\"[Supplementary Concept] OR \"glutens\"[All Fields] OR \"gluten\"[All Fields] OR \"glutens\"[MeSH Terms]) OR ((\"eating\"[MeSH Terms] OR \"eating\"[All Fields]) AND \"disorder*\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "diet",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diet* OR FODMAP OR fibre OR fiber OR gluten OR eating disorder*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diet*\"[All Fields] OR (\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"glutens\"[Supplementary Concept] OR \"glutens\"[All Fields] OR \"gluten\"[All Fields] OR \"glutens\"[MeSH Terms]) OR ((\"eating\"[MeSH Terms] OR \"eating\"[All Fields]) AND \"disorder*\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "antispasmodics",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antispasmodic* OR peppermint OR mebeverine OR otilonium) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antispasmodic*\"[All Fields] OR (\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]) OR (\"mebeverine\"[Supplementary Concept] OR \"mebeverine\"[All Fields]) OR (\"octylonium\"[Supplementary Concept] OR \"octylonium\"[All Fields] OR \"otilonium\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "antispasmodics",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antispasmodic* OR peppermint OR mebeverine OR otilonium) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antispasmodic*\"[All Fields] OR (\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]) OR (\"mebeverine\"[Supplementary Concept] OR \"mebeverine\"[All Fields]) OR (\"octylonium\"[Supplementary Concept] OR \"octylonium\"[All Fields] OR \"otilonium\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "ibs-c",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (constipation OR linaclotide OR tenapanor OR lubiprostone OR plecanatide OR secretagogue) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "4",
   "idlist": [
    "42943524",
    "42934967",
    "42934540",
    "42928586"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"constipation\"[MeSH Terms] OR \"constipation\"[All Fields] OR \"constipated\"[All Fields] OR \"constipating\"[All Fields] OR \"constipations\"[All Fields] OR (\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields]) OR (\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]) OR (\"lubiprostone\"[Supplementary Concept] OR \"lubiprostone\"[All Fields] OR \"lubiprostone\"[MeSH Terms]) OR (\"plecanatide\"[Supplementary Concept] OR \"plecanatide\"[All Fields]) OR (\"secretagogues\"[Supplementary Concept] OR \"secretagogues\"[All Fields] OR \"secretagogue\"[All Fields] OR \"secretagogues\"[MeSH Terms])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "ibs-c",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (constipation OR linaclotide OR tenapanor OR lubiprostone OR plecanatide OR secretagogue) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"constipation\"[MeSH Terms] OR \"constipation\"[All Fields] OR \"constipated\"[All Fields] OR \"constipating\"[All Fields] OR \"constipations\"[All Fields] OR (\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields]) OR (\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]) OR (\"lubiprostone\"[Supplementary Concept] OR \"lubiprostone\"[All Fields] OR \"lubiprostone\"[MeSH Terms]) OR (\"plecanatide\"[Supplementary Concept] OR \"plecanatide\"[All Fields]) OR (\"secretagogues\"[Supplementary Concept] OR \"secretagogues\"[All Fields] OR \"secretagogue\"[All Fields] OR \"secretagogues\"[MeSH Terms])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "ibs-d",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diarrhea OR diarrhoea OR eluxadoline OR alosetron OR ramosetron OR ondansetron) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "8",
   "idlist": [
    "42934540",
    "42928586",
    "42919315",
    "42909825",
    "42908452",
    "42904019",
    "42902396",
    "42833252"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields] OR (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]) OR (\"eluxadoline\"[Supplementary Concept] OR \"eluxadoline\"[All Fields]) OR (\"alosetron\"[Supplementary Concept] OR \"alosetron\"[All Fields]) OR (\"ramosetron\"[Supplementary Concept] OR \"ramosetron\"[All Fields]) OR (\"ondansetron\"[Supplementary Concept] OR \"ondansetron\"[All Fields] OR \"ondansetron\"[MeSH Terms] OR \"ondansetrone\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "ibs-d",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diarrhea OR diarrhoea OR eluxadoline OR alosetron OR ramosetron OR ondansetron) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields] OR (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]) OR (\"eluxadoline\"[Supplementary Concept] OR \"eluxadoline\"[All Fields]) OR (\"alosetron\"[Supplementary Concept] OR \"alosetron\"[All Fields]) OR (\"ramosetron\"[Supplementary Concept] OR \"ramosetron\"[All Fields]) OR (\"ondansetron\"[Supplementary Concept] OR \"ondansetron\"[All Fields] OR \"ondansetron\"[MeSH Terms] OR \"ondansetrone\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "rifaximin-sibo",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (rifaximin OR SIBO OR bacterial overgrowth OR methane OR methanogen* OR statin) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "3",
   "idlist": [
    "42942808",
    "42934967",
    "42927267"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields] OR \"SIBO\"[All Fields] OR ((\"bacterial\"[All Fields] OR \"bacterially\"[All Fields] OR \"bacterials\"[All Fields]) AND (\"overgrowth\"[All Fields] OR \"overgrowths\"[All Fields])) OR (\"methanation\"[All Fields] OR \"methane\"[Supplementary Concept] OR \"methane\"[All Fields] OR \"methane\"[MeSH Terms] OR \"methane s\"[All Fields] OR \"methanes\"[All Fields] OR \"methanization\"[All Fields] OR \"methanizer\"[All Fields]) OR \"methanogen*\"[All Fields] OR (\"hydroxymethylglutaryl coa reductase inhibitors\"[Pharmacological Action] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[Supplementary Concept] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[All Fields] OR \"statin\"[All Fields] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[MeSH Terms] OR (\"hydroxymethylglutaryl coa\"[All Fields] AND \"reductase\"[All Fields] AND \"inhibitors\"[All Fields]) OR \"statins\"[All Fields] OR \"statin s\"[All Fields] OR \"statine\"[Supplementary Concept] OR \"statine\"[All Fields] OR \"statines\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "rifaximin-sibo",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (rifaximin OR SIBO OR bacterial overgrowth OR methane OR methanogen* OR statin) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields] OR \"SIBO\"[All Fields] OR ((\"bacterial\"[All Fields] OR \"bacterially\"[All Fields] OR \"bacterials\"[All Fields]) AND (\"overgrowth\"[All Fields] OR \"overgrowths\"[All Fields])) OR (\"methanation\"[All Fields] OR \"methane\"[Supplementary Concept] OR \"methane\"[All Fields] OR \"methane\"[MeSH Terms] OR \"methane s\"[All Fields] OR \"methanes\"[All Fields] OR \"methanization\"[All Fields] OR \"methanizer\"[All Fields]) OR \"methanogen*\"[All Fields] OR (\"hydroxymethylglutaryl coa reductase inhibitors\"[Pharmacological Action] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[Supplementary Concept] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[All Fields] OR \"statin\"[All Fields] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[MeSH Terms] OR (\"hydroxymethylglutaryl coa\"[All Fields] AND \"reductase\"[All Fields] AND \"inhibitors\"[All Fields]) OR \"statins\"[All Fields] OR \"statin s\"[All Fields] OR \"statine\"[Supplementary Concept] OR \"statine\"[All Fields] OR \"statines\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "neuromodulators",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antidepress* OR amitriptyline OR neuromodulat* OR pregabalin OR SSRI OR duloxetine) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "1",
   "idlist": [
    "42942808"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antidepress*\"[All Fields] OR (\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline s\"[All Fields]) OR \"neuromodulat*\"[All Fields] OR (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields]) OR (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine s\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "neuromodulators",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antidepress* OR amitriptyline OR neuromodulat* OR pregabalin OR SSRI OR duloxetine) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antidepress*\"[All Fields] OR (\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline s\"[All Fields]) OR \"neuromodulat*\"[All Fields] OR (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields]) OR (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine s\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "psychological-therapy",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (psychotherap* OR cognitive behav* OR hypnotherap* OR behavioral OR behavioural) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "6",
   "idlist": [
    "42942061",
    "42941862",
    "42939282",
    "42914364",
    "42909825",
    "42908445"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"psychotherap*\"[All Fields] OR ((\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields]) AND \"behav*\"[All Fields]) OR \"hypnotherap*\"[All Fields] OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]) OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "psychological-therapy",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (psychotherap* OR cognitive behav* OR hypnotherap* OR behavioral OR behavioural) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"psychotherap*\"[All Fields] OR ((\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields]) AND \"behav*\"[All Fields]) OR \"hypnotherap*\"[All Fields] OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]) OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "placebo-trial-design",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (placebo OR nocebo OR endpoint OR trial design OR label*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "4",
   "idlist": [
    "42934540",
    "42927267",
    "42908445",
    "42902396"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms] OR (\"nocebo effect\"[MeSH Terms] OR (\"nocebo\"[All Fields] AND \"effect\"[All Fields]) OR \"nocebo effect\"[All Fields] OR \"nocebo\"[All Fields] OR \"nocebos\"[All Fields]) OR (\"endpoint\"[All Fields] OR \"endpoints\"[All Fields]) OR ((\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]) AND (\"design\"[All Fields] OR \"design s\"[All Fields] OR \"designabilities\"[All Fields] OR \"designability\"[All Fields] OR \"designable\"[All Fields] OR \"designed\"[All Fields] OR \"designer\"[All Fields] OR \"designer s\"[All Fields] OR \"designers\"[All Fields] OR \"designing\"[All Fields] OR \"designs\"[All Fields])) OR \"label*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "placebo-trial-design",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (placebo OR nocebo OR endpoint OR trial design OR label*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms] OR (\"nocebo effect\"[MeSH Terms] OR (\"nocebo\"[All Fields] AND \"effect\"[All Fields]) OR \"nocebo effect\"[All Fields] OR \"nocebo\"[All Fields] OR \"nocebos\"[All Fields]) OR (\"endpoint\"[All Fields] OR \"endpoints\"[All Fields]) OR ((\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]) AND (\"design\"[All Fields] OR \"design s\"[All Fields] OR \"designabilities\"[All Fields] OR \"designability\"[All Fields] OR \"designable\"[All Fields] OR \"designed\"[All Fields] OR \"designer\"[All Fields] OR \"designer s\"[All Fields] OR \"designers\"[All Fields] OR \"designing\"[All Fields] OR \"designs\"[All Fields])) OR \"label*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "dyspepsia-overlap",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (dyspepsia OR overlap OR comorbid*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "6",
   "idlist": [
    "42918294",
    "42910824",
    "42908452",
    "42908445",
    "42904019",
    "42902396"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"dyspepsia\"[MeSH Terms] OR \"dyspepsia\"[All Fields] OR \"dyspepsias\"[All Fields] OR (\"overlap\"[All Fields] OR \"overlapped\"[All Fields] OR \"overlapping\"[All Fields] OR \"overlappings\"[All Fields] OR \"overlaps\"[All Fields]) OR \"comorbid*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "dyspepsia-overlap",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (dyspepsia OR overlap OR comorbid*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"dyspepsia\"[MeSH Terms] OR \"dyspepsia\"[All Fields] OR \"dyspepsias\"[All Fields] OR (\"overlap\"[All Fields] OR \"overlapped\"[All Fields] OR \"overlapping\"[All Fields] OR \"overlappings\"[All Fields] OR \"overlaps\"[All Fields]) OR \"comorbid*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "guidelines",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (guideline[pt] OR practice guideline[pt] OR guideline*[tiab] OR consensus[tiab] OR position paper[tiab]) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "4",
   "idlist": [
    "42939282",
    "42927267",
    "42918294",
    "42903081"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"guideline\"[Publication Type] OR \"practice guideline\"[Publication Type] OR \"guideline*\"[Title/Abstract] OR \"consensus\"[Title/Abstract] OR \"position paper\"[Title/Abstract]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "guidelines",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (guideline[pt] OR practice guideline[pt] OR guideline*[tiab] OR consensus[tiab] OR position paper[tiab]) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"guideline\"[Publication Type] OR \"practice guideline\"[Publication Type] OR \"guideline*\"[Title/Abstract] OR \"consensus\"[Title/Abstract] OR \"position paper\"[Title/Abstract]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "patient-experience",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (qualitative OR stigma OR quality of life OR patient experience OR patient reported OR work impairment) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "8",
   "idlist": [
    "42943524",
    "42940160",
    "42939282",
    "42927267",
    "42918294",
    "42908452",
    "42903081",
    "42902396"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields] OR (\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma s\"[All Fields]) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"experience\"[All Fields] OR \"experience s\"[All Fields] OR \"experiences\"[All Fields])) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR ((\"work\"[MeSH Terms] OR \"work\"[All Fields]) AND (\"impair\"[All Fields] OR \"impaired\"[All Fields] OR \"impairement\"[All Fields] OR \"impairements\"[All Fields] OR \"impairing\"[All Fields] OR \"impairment\"[All Fields] OR \"impairments\"[All Fields] OR \"impairs\"[All Fields]))) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "patient-experience",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (qualitative OR stigma OR quality of life OR patient experience OR patient reported OR work impairment) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields] OR (\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma s\"[All Fields]) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"experience\"[All Fields] OR \"experience s\"[All Fields] OR \"experiences\"[All Fields])) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR ((\"work\"[MeSH Terms] OR \"work\"[All Fields]) AND (\"impair\"[All Fields] OR \"impaired\"[All Fields] OR \"impairement\"[All Fields] OR \"impairements\"[All Fields] OR \"impairing\"[All Fields] OR \"impairment\"[All Fields] OR \"impairments\"[All Fields] OR \"impairs\"[All Fields]))) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  },
  {
   "topic": "novel-trials",
   "kind": "topic",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (camlipixant OR brenipatide OR LY3537031 OR ebastine OR REFIT2 OR virtual dietitian) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"camlipixant\"[All Fields] OR (\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]) OR \"REFIT2\"[All Fields] OR ((\"virtual\"[All Fields] OR \"virtuality\"[All Fields] OR \"virtualization\"[All Fields] OR \"virtualized\"[All Fields] OR \"virtualizing\"[All Fields] OR \"virtuals\"[All Fields]) AND (\"dietitian s\"[All Fields] OR \"nutritionists\"[MeSH Terms] OR \"nutritionists\"[All Fields] OR \"dietitian\"[All Fields] OR \"dietitians\"[All Fields]))) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "topic": "novel-trials",
   "kind": "cochrane",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (camlipixant OR brenipatide OR LY3537031 OR ebastine OR REFIT2 OR virtual dietitian) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"camlipixant\"[All Fields] OR (\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]) OR \"REFIT2\"[All Fields] OR ((\"virtual\"[All Fields] OR \"virtuality\"[All Fields] OR \"virtualization\"[All Fields] OR \"virtualized\"[All Fields] OR \"virtualizing\"[All Fields] OR \"virtuals\"[All Fields]) AND (\"dietitian s\"[All Fields] OR \"nutritionists\"[MeSH Terms] OR \"nutritionists\"[All Fields] OR \"dietitian\"[All Fields] OR \"dietitians\"[All Fields]))) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]"
  }
 ],
 "pubmed_unique_topic_ids": [
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 ],
 "cochrane_summary": {
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  "hits": 0
 },
 "supplemental_pubmed_searches": [
  {
   "label": "cochrane-ibs-2026",
   "query": "\"Cochrane Database Syst Rev\"[jour] AND (irritable bowel OR \"functional bowel\" OR \"disorders of gut-brain interaction\") AND 2026/01/01:2026/12/31[EDAT]",
   "count": "0",
   "idlist": [],
   "querytranslation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"irritable bowel syndrome\"[MeSH Terms] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields] AND \"syndrome\"[All Fields]) OR \"irritable bowel syndrome\"[All Fields] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields]) OR \"irritable bowel\"[All Fields] OR \"functional bowel\"[All Fields] OR \"disorders of gut-brain interaction\"[All Fields]) AND 2026/01/01:2026/12/31[Date - Entry]"
  },
  {
   "label": "cochrane-related-window",
   "query": "\"Cochrane Database Syst Rev\"[jour] AND (FODMAP OR peppermint OR antispasmodic OR linaclotide OR rifaximin OR probiotic* OR hypnotherapy OR amitriptyline OR \"faecal microbiota\" OR \"fecal microbiota\") AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields] OR (\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]) OR (\"parasympatholytics\"[Pharmacological Action] OR \"parasympatholytics\"[Supplementary Concept] OR \"parasympatholytics\"[All Fields] OR \"antispasmodic\"[All Fields] OR \"parasympatholytics\"[MeSH Terms] OR \"antispasmodics\"[All Fields]) OR (\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields]) OR (\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields]) OR \"probiotic*\"[All Fields] OR (\"hypnosis\"[MeSH Terms] OR \"hypnosis\"[All Fields] OR \"hypnotherapy\"[All Fields]) OR (\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline s\"[All Fields]) OR \"faecal microbiota\"[All Fields] OR \"fecal microbiota\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "german-s3-canadian",
   "query": "(irritable bowel OR Reizdarmsyndrom) AND (DGVS OR Leitlinie OR S3 OR \"Canadian Association of Gastroenterology\") AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields] AND \"syndrome\"[All Fields]) OR \"irritable bowel syndrome\"[All Fields] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields]) OR \"irritable bowel\"[All Fields] OR \"Reizdarmsyndrom\"[All Fields]) AND (\"DGVS\"[All Fields] OR \"Leitlinie\"[All Fields] OR \"S3\"[All Fields] OR \"Canadian Association of Gastroenterology\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "rome-v-guideline",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (\"Rome V\" OR \"Rome 5\") AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "1",
   "idlist": [
    "42924828"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"Rome V\"[All Fields] OR \"Rome 5\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "refit2",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (REFIT2 OR (faecal microbiota transplantation AND Norway)) AND 2026/09/01:2026/10/28[EDAT]",
   "count": "1",
   "idlist": [
    "42785338"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"REFIT2\"[All Fields] OR ((\"faecal microbiota transplantation\"[All Fields] OR \"fecal microbiota transplantation\"[MeSH Terms] OR (\"fecal\"[All Fields] AND \"microbiota\"[All Fields] AND \"transplantation\"[All Fields]) OR \"fecal microbiota transplantation\"[All Fields]) AND (\"norway\"[MeSH Terms] OR \"norway\"[All Fields] OR \"norway s\"[All Fields] OR \"norways\"[All Fields]))) AND 2026/09/01:2026/10/28[Date - Entry]"
  },
  {
   "label": "suicide-adult",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (suicid*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "1",
   "idlist": [
    "42906826"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND \"suicid*\"[All Fields] AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "open-label-placebo",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (\"open-label placebo\" OR \"open label placebo\") AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"open-label placebo\"[All Fields] OR \"open-label placebo\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "post-infectious-prevention",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (postinfect* OR post-infect*) AND (prevent* OR prophyla*) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"postinfect*\"[All Fields] OR \"post infect*\"[All Fields]) AND (\"prevent*\"[All Fields] OR \"prophyla*\"[All Fields]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "pipeline",
   "query": "(camlipixant OR brenipatide OR LY3537031 OR ebastine OR tenapanor OR \"EBX-102\") AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "2",
   "idlist": [
    "42937709",
    "42905296"
   ],
   "querytranslation": "(\"camlipixant\"[All Fields] OR (\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]) OR (\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "glp1-ibs",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (GLP-1 OR \"glucagon-like peptide\" OR semaglutide OR tirzepatide) AND 2026/01/01:2026/10/28[EDAT]",
   "count": "8",
   "idlist": [
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    "42918357",
    "42590035",
    "42570075",
    "42504661",
    "42037908",
    "41974246",
    "41480755"
   ],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"glucagon like peptide 1\"[Supplementary Concept] OR \"glucagon like peptide 1\"[All Fields] OR \"glp 1\"[All Fields] OR \"glucagon like peptide 1\"[MeSH Terms] OR \"glucagon-like peptide\"[All Fields] OR (\"semaglutide\"[Supplementary Concept] OR \"semaglutide\"[All Fields] OR \"semaglutide\"[MeSH Terms]) OR (\"tirzepatide\"[Supplementary Concept] OR \"tirzepatide\"[All Fields] OR \"tirzepatide\"[MeSH Terms])) AND 2026/01/01:2026/10/28[Date - Entry]"
  },
  {
   "label": "mortality-rome",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND mortality AND (Rome IV OR Rome V) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) AND (((\"rome\"[MeSH Terms] OR \"rome\"[All Fields]) AND (\"ieee intell veh symp\"[Journal] OR \"iv\"[All Fields])) OR rome v[Author]) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "eating-disorder-fodmap",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (eating disorder* OR ARFID) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (((\"eating\"[MeSH Terms] OR \"eating\"[All Fields]) AND \"disorder*\"[All Fields]) OR (\"avoidant restrictive food intake disorder\"[MeSH Terms] OR (\"avoidant\"[All Fields] AND \"restrictive\"[All Fields] AND \"food\"[All Fields] AND \"intake\"[All Fields] AND \"disorder\"[All Fields]) OR \"avoidant restrictive food intake disorder\"[All Fields] OR \"arfid\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  },
  {
   "label": "head-to-head",
   "query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (amitriptyline OR neuromodulator*) AND (cognitive OR hypnotherapy) AND ((2026/10/21[PDAT] : 2026/10/28[PDAT]) OR (2026/10/21[EDAT] : 2026/10/28[EDAT]))",
   "count": "0",
   "idlist": [],
   "querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline s\"[All Fields] OR \"neuromodulator*\"[All Fields]) AND (\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields] OR (\"hypnosis\"[MeSH Terms] OR \"hypnosis\"[All Fields] OR \"hypnotherapy\"[All Fields])) AND (2026/10/21:2026/10/28[Date - Publication] OR 2026/10/21:2026/10/28[Date - Entry])"
  }
 ],
 "europe_pmc_searches": [
  {
   "topic": "overview",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 152,
   "error": null,
   "record_ids": [
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    "42941862",
    "PPR1351286",
    "42934967",
    "42918294",
    "42942808",
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    "42897685",
    "42923524",
    "PMC13707484",
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    "PPR1351404",
    "PMC13705360",
    "PMC13692849",
    "PMC13707944",
    "PMC13702532",
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    "42904019",
    "42898188",
    "42894232",
    "PMC13700867",
    "PMC13704092",
    "42899209",
    "PMC13704906",
    "42923363",
    "42894828",
    "PMC13708323",
    "PMC13705286",
    "PMC13704349",
    "42921189",
    "PMC13701723",
    "PMC13707582",
    "42902438",
    "42921282",
    "42895010",
    "PMC13696305",
    "PMC13705954",
    "PMC13709476",
    "42895003",
    "PMC13692248",
    "42903381",
    "PMC13704242",
    "42903244",
    "PMC13702083",
    "PMC13700554",
    "42909399",
    "PMC13708281",
    "42924812",
    "42910538",
    "PMC13704369",
    "PMC13704771",
    "42923724",
    "42924791",
    "42922994",
    "PMC13684677",
    "42923558",
    "PMC13708356",
    "42927507",
    "42912092",
    "42904210",
    "PMC13707139",
    "42903407",
    "PMC13708125",
    "PMC13708468",
    "PMC13701600",
    "42901599",
    "42905730",
    "42900758",
    "PMC13704365",
    "PMC13696481",
    "42929818",
    "PMC13708226",
    "42910248",
    "42908841",
    "PMC13691306",
    "PMC13706956",
    "42903958",
    "PMC13706855",
    "PMC13708285",
    "PMC13704118",
    "PMC13702003",
    "PMC13700855",
    "42902182",
    "PMC13706681",
    "PMC13709890",
    "42905293",
    "PMC13707845",
    "42898166",
    "42903641",
    "42898211",
    "PMC13707552",
    "42895014",
    "42921332",
    "PMC13704079",
    "42929947",
    "PMC13705037",
    "42921375",
    "PMC13708521",
    "42924825",
    "PMC13693052",
    "PMC13705594",
    "PMC13704569",
    "PMC13707104",
    "PMC13692019",
    "PMC13706364",
    "42897663",
    "PMC13701933",
    "PMC13696426",
    "PMC13708450",
    "PMC13690684",
    "42899159",
    "42903465",
    "PMC13704869",
    "42903914"
   ]
  },
  {
   "topic": "diagnosis-rome",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (Rome OR diagnos* OR criteria OR biomarker*) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 126,
   "error": null,
   "record_ids": [
    "42928586",
    "42901246",
    "42919315",
    "42940160",
    "42927267",
    "42903081",
    "PMC13702017",
    "42833252",
    "42928090",
    "42918294",
    "42924828",
    "42923351",
    "42894533",
    "42934967",
    "42936312",
    "PMC13702283",
    "PPR1347576",
    "PPR1351286",
    "42909342",
    "PMC13707944",
    "42942808",
    "42903485",
    "42923306",
    "42910244",
    "PMC13692849",
    "42910145",
    "42907149",
    "42923524",
    "PMC13704092",
    "42902396",
    "42897685",
    "42901254",
    "42904019",
    "PMC13707484",
    "42924253",
    "PMC13700867",
    "42894232",
    "PMC13705360",
    "PMC13702532",
    "42924812",
    "42927134",
    "42903244",
    "PMC13706855",
    "PMC13704906",
    "PMC13708323",
    "42902438",
    "42898188",
    "PMC13707582",
    "PMC13705286",
    "42903381",
    "PMC13696305",
    "42921282",
    "PMC13705954",
    "PMC13707552",
    "42905730",
    "42894828",
    "42923724",
    "PMC13704349",
    "42923363",
    "PMC13700554",
    "42895010",
    "42921189",
    "PMC13704242",
    "42927507",
    "42924791",
    "42895003",
    "PMC13702083",
    "42901599",
    "42909399",
    "PMC13704118",
    "PMC13684677",
    "PMC13704369",
    "PMC13704771",
    "PMC13709476",
    "PMC13696481",
    "42910538",
    "42912092",
    "PMC13708281",
    "PMC13708125",
    "PMC13707104",
    "42922994",
    "PMC13707139",
    "PMC13708226",
    "PMC13704365",
    "PMC13691306",
    "PMC13708356",
    "42895014",
    "PMC13702003",
    "42900758",
    "42902182",
    "42904210",
    "PMC13708468",
    "PMC13701600",
    "42923558",
    "PMC13706956",
    "PMC13709890",
    "42898211",
    "42903407",
    "PMC13704569",
    "PMC13700855",
    "42898166",
    "PMC13706364",
    "42929818",
    "42903958",
    "PMC13693052",
    "PMC13708285",
    "42924825",
    "42910248",
    "42908841",
    "PMC13707845",
    "PMC13701933",
    "PMC13708521",
    "PMC13706681",
    "42905293",
    "42921332",
    "PMC13690684",
    "42899159",
    "PMC13708450",
    "PMC13705037",
    "42903641",
    "PMC13696426",
    "42897663",
    "PMC13704079",
    "PMC13704869",
    "42903465",
    "42903914"
   ]
  },
  {
   "topic": "epidemiology-burden",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (prevalence OR incidence OR epidemiolog* OR mortality OR burden OR cost*) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 114,
   "error": null,
   "record_ids": [
    "PPR1347211",
    "42928586",
    "42909825",
    "42918357",
    "42833252",
    "PMC13702017",
    "42934967",
    "42927267",
    "42923524",
    "PMC13702283",
    "PPR1347716",
    "42918294",
    "42927134",
    "42903081",
    "42924253",
    "42897685",
    "42907149",
    "42903485",
    "42923351",
    "PMC13700867",
    "42910244",
    "42910145",
    "42923306",
    "PMC13692849",
    "PMC13707484",
    "PPR1351404",
    "42904019",
    "PMC13704092",
    "42921189",
    "PMC13707944",
    "PMC13696305",
    "42902438",
    "42894232",
    "42902396",
    "42898188",
    "42901599",
    "42895003",
    "42895010",
    "42903244",
    "PMC13704349",
    "42923363",
    "42924812",
    "PMC13705954",
    "PMC13707582",
    "PMC13704906",
    "42903381",
    "42910538",
    "PMC13705286",
    "42921282",
    "PMC13709476",
    "PMC13701600",
    "PMC13700554",
    "PMC13708323",
    "PMC13704242",
    "PMC13701723",
    "PMC13708226",
    "42912092",
    "42921332",
    "PMC13708285",
    "PMC13701933",
    "42927507",
    "PMC13707104",
    "42923724",
    "PMC13707139",
    "PMC13692248",
    "PMC13708281",
    "PMC13704369",
    "PMC13706364",
    "PMC13700855",
    "PMC13708125",
    "PMC13704118",
    "42904210",
    "42909399",
    "PMC13702083",
    "42903407",
    "42905730",
    "42929818",
    "PMC13706855",
    "42903465",
    "42924791",
    "42902182",
    "PMC13704771",
    "PMC13704365",
    "42898166",
    "PMC13708356",
    "42895014",
    "PMC13696481",
    "42924825",
    "42903958",
    "PMC13708468",
    "PMC13709890",
    "PMC13706681",
    "PMC13706956",
    "42910248",
    "42908841",
    "42899159",
    "PMC13705594",
    "PMC13692019",
    "PMC13702003",
    "42903641",
    "PMC13707552",
    "42897663",
    "PMC13708450",
    "PMC13708521",
    "42929947",
    "PMC13707845",
    "42898211",
    "PMC13696426",
    "PMC13704569",
    "PMC13704079",
    "PMC13693052",
    "PMC13690684",
    "42903914",
    "PMC13704869"
   ]
  },
  {
   "topic": "differential-safety",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (differential OR celiac OR coeliac OR microscopic colitis OR bile acid OR alarm OR safety OR adverse OR suicid*) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 129,
   "error": null,
   "record_ids": [
    "PPR1347576",
    "42903485",
    "42928090",
    "42918294",
    "PMC13702017",
    "42934540",
    "42942061",
    "42919315",
    "PPR1348784",
    "42927267",
    "42906826",
    "42909342",
    "42908445",
    "42941862",
    "42909825",
    "42914364",
    "42903081",
    "42902396",
    "42910145",
    "PMC13705360",
    "PPR1351286",
    "PMC13707484",
    "PMC13691306",
    "PPR1351404",
    "PMC13700554",
    "PMC13707944",
    "42907149",
    "PMC13700867",
    "42923351",
    "PMC13702283",
    "42897266",
    "42901254",
    "42923524",
    "42910244",
    "42894232",
    "PMC13704906",
    "42898188",
    "42897685",
    "42927134",
    "PMC13709476",
    "PMC13702003",
    "42923306",
    "PMC13702532",
    "42909399",
    "42904019",
    "PMC13692849",
    "PMC13708323",
    "42902438",
    "42921282",
    "42898166",
    "PMC13701723",
    "PMC13696481",
    "PMC13708468",
    "PMC13707582",
    "42905293",
    "PMC13700855",
    "PMC13704092",
    "42921189",
    "42929947",
    "PMC13705286",
    "PMC13704369",
    "PMC13706681",
    "42904210",
    "42927507",
    "PMC13708285",
    "42895010",
    "42899159",
    "PMC13708281",
    "PMC13704079",
    "PMC13704349",
    "42894828",
    "PMC13696305",
    "PMC13692248",
    "42899209",
    "42923363",
    "PMC13701600",
    "PMC13708521",
    "42898211",
    "42903407",
    "42895014",
    "42924825",
    "42910538",
    "PMC13707104",
    "PMC13705954",
    "PMC13708125",
    "PMC13705037",
    "42923724",
    "42910248",
    "42922994",
    "42903244",
    "PMC13692019",
    "PMC13693052",
    "PMC13709890",
    "PMC13704771",
    "42924791",
    "PMC13707139",
    "42924812",
    "PMC13708226",
    "42903641",
    "42895003",
    "PMC13705594",
    "PMC13708356",
    "42903381",
    "42929818",
    "PMC13690684",
    "PMC13704569",
    "42923558",
    "42912092",
    "PMC13706855",
    "42905730",
    "42903465",
    "42903958",
    "42901599",
    "42902182",
    "42921375",
    "42921332",
    "PMC13707552",
    "42900758",
    "PMC13704118",
    "PMC13707845",
    "PMC13704365",
    "PMC13706956",
    "42908841",
    "PMC13701933",
    "42903914",
    "PMC13704869",
    "PMC13696426",
    "42897663",
    "PMC13708450"
   ]
  },
  {
   "topic": "brain-gut",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (visceral OR hypersensitiv* OR brain OR neural OR genetic* OR enterochromaffin) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 116,
   "error": null,
   "record_ids": [
    "42928090",
    "42924828",
    "42908452",
    "42908445",
    "42914364",
    "42942061",
    "42899209",
    "42936312",
    "PMC13707484",
    "42933944",
    "42894533",
    "42833252",
    "PMC13702017",
    "PMC13702283",
    "42928586",
    "42939282",
    "42927267",
    "42903081",
    "42941862",
    "42909399",
    "42898166",
    "PMC13705360",
    "42897987",
    "42918294",
    "42934967",
    "42942808",
    "PMC13702003",
    "PPR1347716",
    "42910824",
    "42909342",
    "42903485",
    "PMC13705954",
    "42902438",
    "42897685",
    "PMC13702532",
    "PMC13704906",
    "PMC13692849",
    "42904210",
    "42923558",
    "42924253",
    "42907149",
    "PMC13707944",
    "42923524",
    "PMC13701723",
    "42927134",
    "PMC13708356",
    "PMC13708323",
    "42923306",
    "42904019",
    "42924825",
    "42894232",
    "42902396",
    "42929818",
    "42903244",
    "42898188",
    "42922994",
    "PMC13704771",
    "42895010",
    "42910248",
    "PMC13707582",
    "PMC13704092",
    "42901599",
    "PMC13705286",
    "42923363",
    "PMC13704365",
    "PMC13706956",
    "PMC13702083",
    "PMC13696305",
    "PMC13704242",
    "PMC13707104",
    "PMC13709476",
    "PMC13700554",
    "42903381",
    "PMC13706855",
    "PMC13708281",
    "42895003",
    "42924791",
    "42910538",
    "42927507",
    "42924812",
    "PMC13706364",
    "42897663",
    "42895014",
    "42905293",
    "PMC13709890",
    "PMC13708125",
    "PMC13704369",
    "PMC13708468",
    "42912092",
    "PMC13684677",
    "PMC13696481",
    "42903407",
    "42903958",
    "PMC13707845",
    "42929947",
    "42899159",
    "PMC13708521",
    "PMC13691306",
    "PMC13708285",
    "PMC13700855",
    "42908841",
    "42921332",
    "PMC13704079",
    "PMC13705594",
    "PMC13706681",
    "PMC13707552",
    "42898211",
    "PMC13693052",
    "PMC13690684",
    "PMC13705037",
    "PMC13701933",
    "PMC13692019",
    "PMC13696426",
    "42903465",
    "42903914",
    "PMC13704869"
   ]
  },
  {
   "topic": "microbiome",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (microbiom* OR microbiot* OR probiotic* OR fecal OR faecal OR FMT) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 93,
   "error": null,
   "record_ids": [
    "PPR1348784",
    "PPR1351286",
    "42833252",
    "PMC13707484",
    "42928090",
    "42914364",
    "PMC13707944",
    "PMC13700867",
    "PMC13700554",
    "42942808",
    "PMC13702017",
    "42908452",
    "42941862",
    "PMC13708323",
    "42903081",
    "42943524",
    "42927267",
    "42903485",
    "PPR1347576",
    "42909399",
    "42909342",
    "PMC13702283",
    "42936312",
    "42923306",
    "42904210",
    "42897987",
    "PMC13691306",
    "42910145",
    "42894232",
    "PMC13705360",
    "42927134",
    "42898188",
    "PMC13702003",
    "PMC13692849",
    "PPR1351404",
    "42898166",
    "PMC13704906",
    "42902396",
    "42929818",
    "PMC13707582",
    "PMC13708468",
    "42924812",
    "PMC13700855",
    "PMC13708356",
    "PMC13707104",
    "42905293",
    "PMC13707552",
    "PMC13709476",
    "PMC13692019",
    "PMC13704092",
    "42924825",
    "42895014",
    "42903958",
    "PMC13705594",
    "42923363",
    "42921282",
    "42899209",
    "PMC13708281",
    "PMC13706681",
    "42899159",
    "PMC13705286",
    "PMC13692248",
    "42905730",
    "PMC13701723",
    "42910248",
    "PMC13701600",
    "42902438",
    "PMC13696305",
    "42927507",
    "42910538",
    "PMC13696481",
    "PMC13707139",
    "42901599",
    "PMC13708226",
    "42924791",
    "42903381",
    "PMC13693052",
    "PMC13704771",
    "PMC13707845",
    "PMC13704869",
    "PMC13704369",
    "PMC13704079",
    "PMC13706855",
    "42929947",
    "42903407",
    "PMC13708450",
    "42898211",
    "PMC13705037",
    "PMC13701933",
    "PMC13704569",
    "PMC13709890",
    "42903465",
    "42903914"
   ]
  },
  {
   "topic": "post-infectious",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (postinfect* OR post-infect* OR gastroenteritis OR COVID) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 16,
   "error": null,
   "record_ids": [
    "42907149",
    "42927134",
    "PMC13692849",
    "42921189",
    "PMC13705286",
    "42899209",
    "42902438",
    "PMC13709476",
    "PMC13700855",
    "42901599",
    "42903641",
    "PMC13705594",
    "PMC13696426",
    "PMC13701933",
    "42903914",
    "PMC13704869"
   ]
  },
  {
   "topic": "diet",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (diet* OR FODMAP OR fibre OR fiber OR gluten OR eating disorder*) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 126,
   "error": null,
   "record_ids": [
    "42918294",
    "42903081",
    "PMC13702283",
    "42907149",
    "PMC13702017",
    "PPR1347211",
    "42928090",
    "42833252",
    "42901246",
    "42934540",
    "42933944",
    "42919315",
    "42894533",
    "42908452",
    "42928586",
    "42940160",
    "42914364",
    "42903485",
    "42942061",
    "42924828",
    "42939282",
    "42927267",
    "42894232",
    "PPR1347576",
    "PPR1347716",
    "42934967",
    "42943524",
    "42909399",
    "42904019",
    "42909342",
    "42910824",
    "42910244",
    "PMC13707944",
    "42923524",
    "PMC13707484",
    "42897987",
    "42923351",
    "42923306",
    "42902396",
    "42901254",
    "PMC13705360",
    "42927134",
    "42897685",
    "42921282",
    "PMC13692849",
    "42924253",
    "42898188",
    "PMC13704092",
    "PMC13708285",
    "PMC13700867",
    "42895010",
    "PMC13707552",
    "PMC13708323",
    "42899209",
    "PMC13704906",
    "42903407",
    "PMC13707139",
    "PMC13700554",
    "PMC13708281",
    "PMC13705954",
    "42902438",
    "PMC13707582",
    "42924812",
    "PMC13696305",
    "42904210",
    "PMC13705286",
    "42903381",
    "42895003",
    "42921189",
    "PMC13708356",
    "PMC13701723",
    "PMC13708468",
    "PMC13704365",
    "PMC13709476",
    "42898166",
    "PMC13704771",
    "PMC13706956",
    "42905730",
    "PMC13702003",
    "PMC13704369",
    "PMC13708226",
    "42922994",
    "PMC13706681",
    "PMC13704242",
    "42923558",
    "42905293",
    "42903244",
    "42901599",
    "PMC13701600",
    "PMC13702083",
    "42923724",
    "42924791",
    "PMC13696481",
    "PMC13684677",
    "42929818",
    "42912092",
    "PMC13693052",
    "PMC13704079",
    "42908841",
    "PMC13706855",
    "42903958",
    "42924825",
    "42895014",
    "PMC13709890",
    "42902182",
    "PMC13707845",
    "PMC13708521",
    "42910248",
    "PMC13705037",
    "PMC13704118",
    "PMC13707104",
    "PMC13692019",
    "42898211",
    "PMC13704869",
    "42921332",
    "42929947",
    "PMC13701933",
    "PMC13708450",
    "PMC13705594",
    "PMC13704569",
    "42899159",
    "PMC13706364",
    "42897663",
    "42903465",
    "42903914",
    "PMC13690684"
   ]
  },
  {
   "topic": "antispasmodics",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (antispasmodic* OR peppermint OR mebeverine OR otilonium) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 4,
   "error": null,
   "record_ids": [
    "PMC13702283",
    "42927267",
    "42902396",
    "PMC13707104"
   ]
  },
  {
   "topic": "ibs-c",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (constipation OR linaclotide OR tenapanor OR lubiprostone OR plecanatide OR secretagogue) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 48,
   "error": null,
   "record_ids": [
    "42934540",
    "42934967",
    "42903081",
    "42923351",
    "42927267",
    "PMC13702283",
    "42943524",
    "PMC13702017",
    "42910244",
    "PMC13707484",
    "42897685",
    "PPR1351404",
    "42902396",
    "42923306",
    "PMC13704092",
    "42897987",
    "42904019",
    "PMC13692849",
    "42921282",
    "42894232",
    "PMC13707582",
    "42898188",
    "42898166",
    "42899209",
    "42923363",
    "42924812",
    "42924791",
    "PMC13704906",
    "42903381",
    "PMC13708323",
    "PMC13704349",
    "42905730",
    "42909399",
    "PMC13701723",
    "42921189",
    "42901599",
    "PMC13707139",
    "PMC13708226",
    "42908841",
    "PMC13684677",
    "42927507",
    "PMC13707104",
    "PMC13693052",
    "42903958",
    "PMC13700855",
    "42903641",
    "42924825",
    "42903465"
   ]
  },
  {
   "topic": "ibs-d",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (diarrhea OR diarrhoea OR eluxadoline OR alosetron OR ramosetron OR ondansetron) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 71,
   "error": null,
   "record_ids": [
    "42909825",
    "42934540",
    "PPR1348784",
    "42908452",
    "42833252",
    "42919315",
    "42899209",
    "42927267",
    "PMC13702283",
    "42903081",
    "PMC13702017",
    "42897987",
    "42923351",
    "42903485",
    "42910244",
    "42902396",
    "PMC13707484",
    "PMC13692849",
    "42910145",
    "42897685",
    "PPR1351404",
    "PMC13700867",
    "42923306",
    "42927134",
    "42923524",
    "42904019",
    "PMC13705360",
    "42894232",
    "42894828",
    "PMC13707582",
    "42923363",
    "42903381",
    "PMC13704906",
    "PMC13709476",
    "PMC13708323",
    "PMC13701723",
    "42902438",
    "42921189",
    "PMC13696305",
    "PMC13707139",
    "42901599",
    "PMC13700554",
    "PMC13700855",
    "PMC13708226",
    "PMC13708281",
    "42924812",
    "42924791",
    "PMC13704369",
    "42905730",
    "42909399",
    "PMC13708356",
    "42927507",
    "42903407",
    "PMC13691306",
    "PMC13701600",
    "PMC13696481",
    "42908841",
    "PMC13707104",
    "42903958",
    "PMC13702003",
    "42898166",
    "PMC13693052",
    "PMC13704079",
    "PMC13705594",
    "PMC13707552",
    "42895014",
    "42921375",
    "PMC13696426",
    "42899159",
    "42903914",
    "PMC13704869"
   ]
  },
  {
   "topic": "rifaximin-sibo",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (rifaximin OR SIBO OR bacterial overgrowth OR methane OR methanogen* OR statin) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 73,
   "error": null,
   "record_ids": [
    "42927267",
    "42934967",
    "PMC13707944",
    "PPR1348784",
    "42942808",
    "PMC13708323",
    "PMC13708226",
    "42903081",
    "42943524",
    "PMC13702283",
    "42923363",
    "42903485",
    "42927134",
    "PMC13700867",
    "42923306",
    "PMC13707484",
    "PMC13705360",
    "42902396",
    "PMC13692849",
    "42898188",
    "42899209",
    "42894232",
    "PMC13700855",
    "PMC13707582",
    "42902438",
    "PMC13704906",
    "PMC13701723",
    "PMC13696305",
    "PMC13692248",
    "PMC13709476",
    "42895010",
    "42898166",
    "42927507",
    "42905293",
    "PMC13708281",
    "PMC13700554",
    "PMC13708356",
    "PMC13704369",
    "42929818",
    "PMC13706681",
    "42904210",
    "PMC13701600",
    "PMC13705594",
    "42909399",
    "PMC13704771",
    "42903465",
    "PMC13707139",
    "PMC13696481",
    "PMC13708125",
    "PMC13691306",
    "PMC13708285",
    "PMC13707845",
    "PMC13708468",
    "PMC13692019",
    "42903958",
    "42929947",
    "PMC13702003",
    "42910248",
    "42924825",
    "42895014",
    "PMC13706855",
    "PMC13707104",
    "PMC13708521",
    "PMC13709890",
    "42921332",
    "PMC13704569",
    "PMC13705037",
    "PMC13708450",
    "PMC13704079",
    "PMC13701933",
    "42899159",
    "PMC13704869",
    "42903914"
   ]
  },
  {
   "topic": "neuromodulators",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (antidepress* OR amitriptyline OR neuromodulat* OR pregabalin OR SSRI OR duloxetine) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 38,
   "error": null,
   "record_ids": [
    "42907149",
    "PMC13708323",
    "42942808",
    "42923524",
    "42894533",
    "42927267",
    "PMC13702283",
    "42894828",
    "PMC13702532",
    "42902396",
    "42898188",
    "PMC13704092",
    "PMC13704906",
    "42904210",
    "42898211",
    "42921189",
    "PMC13706956",
    "PMC13707582",
    "42909399",
    "PMC13705954",
    "PMC13709476",
    "42895003",
    "42903244",
    "PMC13702083",
    "PMC13704771",
    "PMC13708356",
    "42912092",
    "42901599",
    "42898166",
    "42921332",
    "PMC13702003",
    "PMC13709890",
    "42905293",
    "42895014",
    "42899159",
    "42924825",
    "PMC13707104",
    "42903465"
   ]
  },
  {
   "topic": "psychological-therapy",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (psychotherap* OR cognitive behav* OR hypnotherap* OR behavioral OR behavioural) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 75,
   "error": null,
   "record_ids": [
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    "42908445",
    "42894533",
    "42914364",
    "42941862",
    "42939282",
    "42923524",
    "PMC13702283",
    "PMC13707484",
    "42902396",
    "PMC13702532",
    "PMC13705360",
    "42895003",
    "PMC13704906",
    "42924253",
    "PMC13707582",
    "42894232",
    "42927134",
    "42909399",
    "42898188",
    "42922994",
    "PMC13708323",
    "PMC13704771",
    "42899209",
    "42910248",
    "PMC13704349",
    "42924812",
    "PMC13708356",
    "42901599",
    "42902438",
    "PMC13708285",
    "42912092",
    "PMC13702083",
    "PMC13709476",
    "PMC13700554",
    "PMC13704242",
    "42924825",
    "PMC13705954",
    "42923558",
    "PMC13706956",
    "42910538",
    "42900758",
    "PMC13704365",
    "42903244",
    "PMC13706364",
    "42929818",
    "PMC13684677",
    "PMC13708281",
    "42904210",
    "PMC13707845",
    "42898166",
    "PMC13709890",
    "42903407",
    "42899159",
    "42903465",
    "PMC13701933",
    "42921332",
    "42898211",
    "PMC13702003",
    "PMC13704118",
    "42903958",
    "PMC13707552",
    "PMC13706681",
    "PMC13704079",
    "42929947",
    "42921375",
    "PMC13693052",
    "PMC13708521",
    "PMC13705594",
    "PMC13704569",
    "PMC13708450",
    "PMC13692019",
    "PMC13696426",
    "PMC13704869",
    "42903914"
   ]
  },
  {
   "topic": "placebo-trial-design",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (placebo OR nocebo OR endpoint OR trial design OR label*) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 115,
   "error": null,
   "record_ids": [
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    "42927267",
    "42934540",
    "PPR1347211",
    "42903081",
    "42901246",
    "42923351",
    "PPR1351286",
    "42908445",
    "42894232",
    "42902396",
    "PMC13707582",
    "PMC13702283",
    "PMC13707484",
    "PMC13700867",
    "PMC13702532",
    "PMC13702017",
    "42942808",
    "42907149",
    "42923524",
    "42922994",
    "42910244",
    "PMC13708468",
    "42903485",
    "PMC13708323",
    "42923306",
    "42910145",
    "42901254",
    "PMC13705360",
    "PMC13704369",
    "42897685",
    "PPR1351404",
    "PMC13707944",
    "42903641",
    "PMC13692849",
    "42921282",
    "PMC13691306",
    "PMC13701600",
    "PMC13708281",
    "42898188",
    "42927507",
    "42904019",
    "42927134",
    "PMC13704092",
    "42909399",
    "PMC13704906",
    "42898211",
    "PMC13701723",
    "42899209",
    "PMC13700554",
    "42921189",
    "PMC13704349",
    "42894828",
    "42923558",
    "PMC13704242",
    "42905730",
    "PMC13707104",
    "PMC13696305",
    "PMC13702003",
    "PMC13709476",
    "PMC13704118",
    "42902438",
    "42903465",
    "PMC13706681",
    "PMC13704365",
    "PMC13702083",
    "PMC13692248",
    "42904210",
    "PMC13705954",
    "PMC13708521",
    "42903244",
    "PMC13684677",
    "PMC13709890",
    "PMC13706956",
    "42924812",
    "PMC13696481",
    "PMC13706855",
    "PMC13707139",
    "42912092",
    "42901599",
    "PMC13708356",
    "PMC13708125",
    "42908841",
    "42910538",
    "PMC13693052",
    "42923724",
    "42898166",
    "PMC13707845",
    "42929818",
    "42903958",
    "42903407",
    "42910248",
    "PMC13704569",
    "PMC13708226",
    "42902182",
    "PMC13690684",
    "PMC13708285",
    "42929947",
    "PMC13707552",
    "42924825",
    "PMC13704079",
    "PMC13708450",
    "42895014",
    "42905293",
    "PMC13701933",
    "PMC13692019",
    "PMC13700855",
    "PMC13705037",
    "PMC13706364",
    "42897663",
    "42921375",
    "42899159",
    "PMC13705594",
    "PMC13696426",
    "PMC13704869"
   ]
  },
  {
   "topic": "dyspepsia-overlap",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (dyspepsia OR overlap OR comorbid*) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 66,
   "error": null,
   "record_ids": [
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    "42908445",
    "PMC13702283",
    "42918294",
    "42897685",
    "42908452",
    "PPR1347716",
    "PMC13702017",
    "42910824",
    "42904019",
    "42923524",
    "42910145",
    "42907149",
    "PMC13707484",
    "42901254",
    "42902396",
    "42921189",
    "PMC13706855",
    "42903244",
    "42927134",
    "PMC13700867",
    "PMC13704906",
    "42899209",
    "42903381",
    "PMC13705954",
    "PMC13704369",
    "PMC13696305",
    "PMC13704118",
    "42908841",
    "PMC13704242",
    "42923724",
    "42924791",
    "42895003",
    "42901599",
    "PMC13702083",
    "42923558",
    "PMC13708281",
    "PMC13696481",
    "42909399",
    "42924812",
    "PMC13704771",
    "42927507",
    "42912092",
    "42904210",
    "42929818",
    "PMC13701600",
    "42902182",
    "PMC13708285",
    "42910248",
    "PMC13702003",
    "PMC13700855",
    "PMC13691306",
    "42895014",
    "42898166",
    "42903641",
    "42898211",
    "42897663",
    "42921332",
    "PMC13704079",
    "PMC13705037",
    "PMC13692019",
    "PMC13701933",
    "PMC13704569",
    "42899159",
    "42903465",
    "42903914"
   ]
  },
  {
   "topic": "guidelines",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (guideline OR consensus OR \"position paper\") AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 40,
   "error": null,
   "record_ids": [
    "42894533",
    "42923524",
    "42927267",
    "PMC13702017",
    "42923351",
    "42910145",
    "PMC13700867",
    "PMC13704092",
    "42910538",
    "PMC13705954",
    "PMC13700855",
    "PMC13700554",
    "PMC13709476",
    "42923724",
    "PMC13702083",
    "PMC13702003",
    "PMC13704369",
    "PMC13704242",
    "42924812",
    "42901599",
    "PMC13701600",
    "42909399",
    "PMC13708281",
    "42900758",
    "42902182",
    "PMC13706364",
    "PMC13701933",
    "42903958",
    "PMC13706855",
    "PMC13691306",
    "42898211",
    "PMC13709890",
    "PMC13707552",
    "42895014",
    "42921332",
    "PMC13704079",
    "42903465",
    "PMC13690684",
    "42899159",
    "PMC13704869"
   ]
  },
  {
   "topic": "patient-experience",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (qualitative OR stigma OR quality of life OR patient experience OR patient reported OR work impairment) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 28,
   "error": null,
   "record_ids": [
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    "42923351",
    "PMC13702532",
    "42927134",
    "42895003",
    "PMC13705954",
    "42903465",
    "42894232",
    "PMC13706364",
    "42924812",
    "42899209",
    "42912092",
    "42909399",
    "42902182",
    "42903381",
    "42904210",
    "PMC13704369",
    "PMC13708226",
    "42924825",
    "PMC13706681",
    "PMC13693052",
    "PMC13708356",
    "42921332",
    "42905293",
    "PMC13701933",
    "42929818",
    "42898166",
    "42929947"
   ]
  },
  {
   "topic": "novel-trials",
   "query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (camlipixant OR brenipatide OR LY3537031 OR ebastine OR REFIT2 OR virtual dietitian) AND (FIRST_PDATE:[2026-10-21 TO 2026-10-28] OR FIRST_IDATE:[2026-10-21 TO 2026-10-28])",
   "hit_count": 3,
   "error": null,
   "record_ids": [
    "42909399",
    "PMC13707139",
    "42921332"
   ]
  }
 ],
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   "id": "PPR1348784",
   "doi": "10.21203/rs.3.rs-11289849/v1",
   "server": "Research Square",
   "decision": "wiki (microbiome, trials) + bibliography, flagged preprint; crossref type posted-content, updated-by none"
  },
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   "id": "PPR1347211",
   "doi": "10.64898/2026.10.20.26365988",
   "server": "medRxiv",
   "decision": "seen; All of Us psychological-health SEM preprint; not incorporated"
  },
  {
   "id": "PPR1351404",
   "doi": "10.21203/rs.3.rs-11496080/v1",
   "server": "Research Square",
   "decision": "seen; single-author multi-omics reanalysis preprint; not incorporated"
  }
 ],
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   "doi": "10.1111/nmo.70472",
   "publication_types": [
    "Journal Article"
   ],
   "crossref_updated_by": null,
   "fulltext_opened": false
  },
  {
   "pmid": "42904019",
   "doi": "10.1159/iid/adeag003",
   "publication_types": [
    "Journal Article"
   ],
   "crossref_updated_by": null,
   "fulltext_opened": true,
   "fulltext_source": "Europe PMC PMC13682709 fullTextXML"
  },
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   "doi": "10.1136/bmjopen-2021-056594",
   "publication_types": [
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    "Journal Article",
    "Research Support, Non-U.S. Gov't"
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   "type": "preprint",
   "crossref_updated_by": null,
   "fulltext_opened": false,
   "note": "Research Square HTML returned 200 but no registration number found in page source; NCT04899869 matched by authors, design and enrolment (61)"
  }
 ],
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   "decision": "screened-not-incorporated"
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  {
   "pmid": "42902396",
   "decision": "seen; paediatric protocol, adult-scoped"
  },
  {
   "pmid": "42903081",
   "decision": "seen; low-FODMAP Bifidobacterium vote-count SR, not incorporated"
  },
  {
   "pmid": "42904019",
   "decision": "wiki+bibliography+statistics (open-access full text Table 1 read)"
  },
  {
   "pmid": "42906826",
   "decision": "seen; no abstract; content unknown; check next sweep"
  },
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   "decision": "screened-not-incorporated"
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   "decision": "screened-not-incorporated"
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   "decision": "screened-not-incorporated"
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  {
   "pmid": "42909825",
   "decision": "seen; eluxadoline Medicare Part D utilisation, not incorporated"
  },
  {
   "pmid": "42910145",
   "decision": "seen; calprotectin reagent, 56 IBS, not incorporated"
  },
  {
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   "decision": "screened-not-incorporated"
  },
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   "pmid": "42914364",
   "decision": "screened-not-incorporated"
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   "decision": "screened-not-incorporated"
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   "decision": "seen; no abstract (commentary on GLP-1 RA in IBS); not incorporated"
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   "decision": "screened-not-incorporated"
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   "decision": "screened-not-incorporated"
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   "decision": "seen; Cureus rifaximin SR, very-low certainty, not incorporated"
  },
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   "decision": "screened-not-incorporated"
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   "decision": "wiki+bibliography+statistics (abstract-level; Wiley full text not opened)"
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  {
   "pmid": "42934540",
   "decision": "seen; plecanatide SR mixing CIC and IBS-C, not incorporated"
  },
  {
   "pmid": "42934967",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42936312",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42939282",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42940160",
   "decision": "seen; zonulin SR, narrative, not incorporated"
  },
  {
   "pmid": "42941862",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42942061",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42942808",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42943524",
   "decision": "screened-not-incorporated"
  },
  {
   "pmid": "42946084",
   "decision": "screened-not-incorporated"
  }
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