{
"condition": "irritable-bowel-syndrome",
"sweep_date": "2026-10-14",
"author_engine": "Codex",
"independent_audit": "not performed; edited wiki pages remain draft",
"window": {
"from": "2026-09-30",
"through": "2026-10-14",
"inclusive": true,
"pubmed_fields": [
"PDAT",
"EDAT"
],
"europe_pmc_fields": [
"FIRST_PDATE",
"FIRST_IDATE"
]
},
"method_notes": [
"Publication-date OR indexing-date window; future issue dates may select papers first online earlier. This is not a claim all retrieved items were first published in the fortnight.",
"Europe PMC all-text matching and indexing-date coverage admit older archive deposits and off-topic records; counts are screening hits, not distinct new IBS studies.",
"Guideline-history follow-ups were also searched without the fortnight restriction, correcting two older omissions.",
"Every added PMID was returned as a primary record by live PubMed E-utilities; every written NCT identifier was returned by the live ClinicalTrials.gov API.",
"No bibliography DOI-only record was added; every added DOI was resolved in Crossref.",
"No git, publishing, frontend regeneration or deployment was run."
],
"pubmed_initial_probe": {
"source": "PubMed E-utilities",
"query": "\"irritable bowel syndrome\" AND 2026/09/30:2026/10/14[dp]",
"count": "66",
"retmax": "66",
"retstart": "0",
"idlist": [
"42866695",
"42865969",
"42861963",
"42861429",
"42860924",
"42860910",
"42859374",
"42854770",
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"42850871",
"42850428",
"42848286",
"42845202",
"42844310",
"42843354",
"42842449",
"42842008",
"42838312",
"42837716",
"42833958",
"42833252",
"42823909",
"42823900",
"42823458",
"42823420",
"42821694",
"42816279",
"42816255",
"42814405",
"42814269",
"42780104",
"42704331",
"42641543",
"42613095",
"42611412",
"42609157",
"42580594",
"42578562",
"42572206",
"42560138",
"42517234",
"42504736",
"42480795",
"42477421",
"42473346",
"42456784",
"42444523",
"42442754",
"42413530",
"42398514",
"42398186",
"42374605",
"42329518",
"42294994",
"42190845",
"42162772",
"42150986",
"42139901",
"42084579",
"41895674",
"41882491",
"41860116",
"41762189",
"41325894",
"40974448",
"40503810"
],
"translationset": [],
"querytranslation": "\"irritable bowel syndrome\"[All Fields] AND 2026/09/30:2026/10/14[Date - Publication]"
},
"pubmed_topic_and_cochrane_searches": [
{
"source": "pubmed",
"topic": "overview",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "78",
"retmax": "78",
"retstart": "0",
"idlist": [
"42866695",
"42865969",
"42861963",
"42861429",
"42860924",
"42860910",
"42859374",
"42854770",
"42853311",
"42850871",
"42850428",
"42848286",
"42846617",
"42845202",
"42844310",
"42843368",
"42843367",
"42843366",
"42843354",
"42842449",
"42842008",
"42839981",
"42839967",
"42838312",
"42837716",
"42834635",
"42833958",
"42833252",
"42831162",
"42824924",
"42823909",
"42823900",
"42823458",
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"42821694",
"42819509",
"42818921",
"42816279",
"42816255",
"42814405",
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"42517234",
"42504736",
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"42473346",
"42456784",
"42444523",
"42442754",
"42413530",
"42398514",
"42398186",
"42374605",
"42329518",
"42294994",
"42190845",
"42162772",
"42150986",
"42139901",
"42084579",
"41895674",
"41882491",
"41860116",
"41762189",
"41325894",
"40974448",
"40503810"
],
"translationset": [],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "overview",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "diagnosis-rome",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (Rome OR diagnos* OR criteria OR biomarker*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "40",
"retmax": "40",
"retstart": "0",
"idlist": [
"42866695",
"42861963",
"42861429",
"42860910",
"42854770",
"42848286",
"42844310",
"42843368",
"42843367",
"42843366",
"42843354",
"42842449",
"42842008",
"42838312",
"42834635",
"42833958",
"42833252",
"42823909",
"42823900",
"42823420",
"42819509",
"42818921",
"42816279",
"42816255",
"42641543",
"42578562",
"42560138",
"42473346",
"42456784",
"42444523",
"42442754",
"42413530",
"42398514",
"42329518",
"42294994",
"42190845",
"42162772",
"41895674",
"41860116",
"40974448"
],
"translationset": [
{
"from": "Rome",
"to": "\"rome\"[MeSH Terms] OR \"rome\"[All Fields]"
},
{
"from": "criteria",
"to": "\"criteria's\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rome\"[MeSH Terms] OR \"rome\"[All Fields] OR \"diagnos*\"[All Fields] OR (\"criteria s\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[MeSH Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]) OR \"biomarker*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "diagnosis-rome",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (Rome OR diagnos* OR criteria OR biomarker*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "Rome",
"to": "\"rome\"[MeSH Terms] OR \"rome\"[All Fields]"
},
{
"from": "criteria",
"to": "\"criteria's\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rome\"[MeSH Terms] OR \"rome\"[All Fields] OR \"diagnos*\"[All Fields] OR (\"criteria s\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[MeSH Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]) OR \"biomarker*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "epidemiology-burden",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (prevalence OR incidence OR epidemiolog* OR mortality OR burden OR cost*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "32",
"retmax": "32",
"retstart": "0",
"idlist": [
"42866695",
"42861429",
"42860910",
"42854770",
"42850871",
"42850428",
"42848286",
"42845202",
"42844310",
"42839981",
"42837716",
"42824924",
"42823909",
"42823900",
"42823420",
"42818921",
"42816279",
"42814269",
"42641543",
"42609157",
"42578562",
"42560138",
"42473346",
"42444523",
"42442754",
"42398186",
"42329518",
"42294994",
"41895674",
"41860116",
"41762189",
"40974448"
],
"translationset": [
{
"from": "prevalence",
"to": "\"epidemiology\"[Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence's\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields]"
},
{
"from": "incidence",
"to": "\"epidemiology\"[Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]"
},
{
"from": "mortality",
"to": "\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[Subheading]"
},
{
"from": "burden",
"to": "\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR \"epidemiolog*\"[All Fields] OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR \"cost*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "epidemiology-burden",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (prevalence OR incidence OR epidemiolog* OR mortality OR burden OR cost*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "prevalence",
"to": "\"epidemiology\"[Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence's\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields]"
},
{
"from": "incidence",
"to": "\"epidemiology\"[Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]"
},
{
"from": "mortality",
"to": "\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[Subheading]"
},
{
"from": "burden",
"to": "\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR \"epidemiolog*\"[All Fields] OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR \"cost*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "differential-safety",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (differential OR celiac OR coeliac OR microscopic colitis OR bile acid OR alarm OR safety OR adverse OR suicid*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "21",
"retmax": "21",
"retstart": "0",
"idlist": [
"42865969",
"42850871",
"42844310",
"42834635",
"42823420",
"42814405",
"42814269",
"42613095",
"42609157",
"42578562",
"42572206",
"42517234",
"42477421",
"42473346",
"42374605",
"42294994",
"42162772",
"42150986",
"41860116",
"41762189",
"40503810"
],
"translationset": [
{
"from": "differential",
"to": "\"cell differentiation\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"differentiation\"[All Fields]) OR \"cell differentiation\"[All Fields] OR \"differentiated\"[All Fields] OR \"differentiation\"[All Fields] OR \"differential\"[All Fields] OR \"differentials\"[All Fields] OR \"differentiate\"[All Fields] OR \"differentiates\"[All Fields] OR \"differentiating\"[All Fields] OR \"differentiational\"[All Fields] OR \"differentiations\"[All Fields] OR \"differentiative\"[All Fields]"
},
{
"from": "celiac",
"to": "\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]"
},
{
"from": "coeliac",
"to": "\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]"
},
{
"from": "microscopic colitis",
"to": "\"colitis, microscopic\"[MeSH Terms] OR (\"colitis\"[All Fields] AND \"microscopic\"[All Fields]) OR \"microscopic colitis\"[All Fields] OR (\"microscopic\"[All Fields] AND \"colitis\"[All Fields])"
},
{
"from": "bile acid",
"to": "\"bile acids and salts\"[Supplementary Concept] OR \"bile acids and salts\"[All Fields] OR \"bile acid\"[All Fields] OR \"bile acids and salts\"[MeSH Terms] OR (\"bile\"[All Fields] AND \"acids\"[All Fields] AND \"salts\"[All Fields]) OR (\"bile\"[All Fields] AND \"acid\"[All Fields])"
},
{
"from": "alarm",
"to": "\"alarm\"[All Fields] OR \"alarm's\"[All Fields] OR \"alarmed\"[All Fields] OR \"alarming\"[All Fields] OR \"alarms\"[All Fields]"
},
{
"from": "safety",
"to": "\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]"
},
{
"from": "adverse",
"to": "\"adverse\"[All Fields] OR \"adversely\"[All Fields] OR \"adverses\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"cell differentiation\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"differentiation\"[All Fields]) OR \"cell differentiation\"[All Fields] OR \"differentiated\"[All Fields] OR \"differentiation\"[All Fields] OR \"differential\"[All Fields] OR \"differentials\"[All Fields] OR \"differentiate\"[All Fields] OR \"differentiates\"[All Fields] OR \"differentiating\"[All Fields] OR \"differentiational\"[All Fields] OR \"differentiations\"[All Fields] OR \"differentiative\"[All Fields] OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"colitis, microscopic\"[MeSH Terms] OR (\"colitis\"[All Fields] AND \"microscopic\"[All Fields]) OR \"microscopic colitis\"[All Fields] OR (\"microscopic\"[All Fields] AND \"colitis\"[All Fields])) OR (\"bile acids and salts\"[Supplementary Concept] OR \"bile acids and salts\"[All Fields] OR \"bile acid\"[All Fields] OR \"bile acids and salts\"[MeSH Terms] OR (\"bile\"[All Fields] AND \"acids\"[All Fields] AND \"salts\"[All Fields]) OR (\"bile\"[All Fields] AND \"acid\"[All Fields])) OR (\"alarm\"[All Fields] OR \"alarm s\"[All Fields] OR \"alarmed\"[All Fields] OR \"alarming\"[All Fields] OR \"alarms\"[All Fields]) OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR (\"adverse\"[All Fields] OR \"adversely\"[All Fields] OR \"adverses\"[All Fields]) OR \"suicid*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "differential-safety",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (differential OR celiac OR coeliac OR microscopic colitis OR bile acid OR alarm OR safety OR adverse OR suicid*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "differential",
"to": "\"cell differentiation\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"differentiation\"[All Fields]) OR \"cell differentiation\"[All Fields] OR \"differentiated\"[All Fields] OR \"differentiation\"[All Fields] OR \"differential\"[All Fields] OR \"differentials\"[All Fields] OR \"differentiate\"[All Fields] OR \"differentiates\"[All Fields] OR \"differentiating\"[All Fields] OR \"differentiational\"[All Fields] OR \"differentiations\"[All Fields] OR \"differentiative\"[All Fields]"
},
{
"from": "celiac",
"to": "\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]"
},
{
"from": "coeliac",
"to": "\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]"
},
{
"from": "microscopic colitis",
"to": "\"colitis, microscopic\"[MeSH Terms] OR (\"colitis\"[All Fields] AND \"microscopic\"[All Fields]) OR \"microscopic colitis\"[All Fields] OR (\"microscopic\"[All Fields] AND \"colitis\"[All Fields])"
},
{
"from": "bile acid",
"to": "\"bile acids and salts\"[Supplementary Concept] OR \"bile acids and salts\"[All Fields] OR \"bile acid\"[All Fields] OR \"bile acids and salts\"[MeSH Terms] OR (\"bile\"[All Fields] AND \"acids\"[All Fields] AND \"salts\"[All Fields]) OR (\"bile\"[All Fields] AND \"acid\"[All Fields])"
},
{
"from": "alarm",
"to": "\"alarm\"[All Fields] OR \"alarm's\"[All Fields] OR \"alarmed\"[All Fields] OR \"alarming\"[All Fields] OR \"alarms\"[All Fields]"
},
{
"from": "safety",
"to": "\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]"
},
{
"from": "adverse",
"to": "\"adverse\"[All Fields] OR \"adversely\"[All Fields] OR \"adverses\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"cell differentiation\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"differentiation\"[All Fields]) OR \"cell differentiation\"[All Fields] OR \"differentiated\"[All Fields] OR \"differentiation\"[All Fields] OR \"differential\"[All Fields] OR \"differentials\"[All Fields] OR \"differentiate\"[All Fields] OR \"differentiates\"[All Fields] OR \"differentiating\"[All Fields] OR \"differentiational\"[All Fields] OR \"differentiations\"[All Fields] OR \"differentiative\"[All Fields] OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"celiac\"[All Fields] OR \"celiacs\"[All Fields] OR \"coeliac\"[All Fields] OR \"coeliacs\"[All Fields]) OR (\"colitis, microscopic\"[MeSH Terms] OR (\"colitis\"[All Fields] AND \"microscopic\"[All Fields]) OR \"microscopic colitis\"[All Fields] OR (\"microscopic\"[All Fields] AND \"colitis\"[All Fields])) OR (\"bile acids and salts\"[Supplementary Concept] OR \"bile acids and salts\"[All Fields] OR \"bile acid\"[All Fields] OR \"bile acids and salts\"[MeSH Terms] OR (\"bile\"[All Fields] AND \"acids\"[All Fields] AND \"salts\"[All Fields]) OR (\"bile\"[All Fields] AND \"acid\"[All Fields])) OR (\"alarm\"[All Fields] OR \"alarm s\"[All Fields] OR \"alarmed\"[All Fields] OR \"alarming\"[All Fields] OR \"alarms\"[All Fields]) OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR (\"adverse\"[All Fields] OR \"adversely\"[All Fields] OR \"adverses\"[All Fields]) OR \"suicid*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "brain-gut",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (visceral OR hypersensitiv* OR brain OR neural OR genetic* OR enterochromaffin) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "36",
"retmax": "36",
"retstart": "0",
"idlist": [
"42866695",
"42865969",
"42861963",
"42860910",
"42853311",
"42848286",
"42843354",
"42842449",
"42838312",
"42834635",
"42833252",
"42824924",
"42823909",
"42823900",
"42823420",
"42821694",
"42816255",
"42814405",
"42780104",
"42704331",
"42641543",
"42611412",
"42572206",
"42560138",
"42517234",
"42504736",
"42480795",
"42473346",
"42444523",
"42413530",
"42398514",
"42398186",
"42190845",
"42084579",
"41860116",
"41325894"
],
"translationset": [
{
"from": "visceral",
"to": "\"visceral\"[All Fields] OR \"viscerally\"[All Fields]"
},
{
"from": "brain",
"to": "\"brain\"[MeSH Terms] OR \"brain\"[All Fields] OR \"brains\"[All Fields] OR \"brain's\"[All Fields]"
},
{
"from": "neural",
"to": "\"neural\"[All Fields] OR \"neuralization\"[All Fields] OR \"neuralize\"[All Fields] OR \"neuralized\"[All Fields] OR \"neuralizes\"[All Fields] OR \"neuralizing\"[All Fields] OR \"neurally\"[All Fields]"
},
{
"from": "enterochromaffin",
"to": "\"enterochromaffin cells\"[MeSH Terms] OR (\"enterochromaffin\"[All Fields] AND \"cells\"[All Fields]) OR \"enterochromaffin cells\"[All Fields] OR \"enterochromaffin\"[All Fields] OR \"enterochromaffine\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"visceral\"[All Fields] OR \"viscerally\"[All Fields] OR \"hypersensitiv*\"[All Fields] OR (\"brain\"[MeSH Terms] OR \"brain\"[All Fields] OR \"brains\"[All Fields] OR \"brain s\"[All Fields]) OR (\"neural\"[All Fields] OR \"neuralization\"[All Fields] OR \"neuralize\"[All Fields] OR \"neuralized\"[All Fields] OR \"neuralizes\"[All Fields] OR \"neuralizing\"[All Fields] OR \"neurally\"[All Fields]) OR \"genetic*\"[All Fields] OR (\"enterochromaffin cells\"[MeSH Terms] OR (\"enterochromaffin\"[All Fields] AND \"cells\"[All Fields]) OR \"enterochromaffin cells\"[All Fields] OR \"enterochromaffin\"[All Fields] OR \"enterochromaffine\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "brain-gut",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (visceral OR hypersensitiv* OR brain OR neural OR genetic* OR enterochromaffin) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "visceral",
"to": "\"visceral\"[All Fields] OR \"viscerally\"[All Fields]"
},
{
"from": "brain",
"to": "\"brain\"[MeSH Terms] OR \"brain\"[All Fields] OR \"brains\"[All Fields] OR \"brain's\"[All Fields]"
},
{
"from": "neural",
"to": "\"neural\"[All Fields] OR \"neuralization\"[All Fields] OR \"neuralize\"[All Fields] OR \"neuralized\"[All Fields] OR \"neuralizes\"[All Fields] OR \"neuralizing\"[All Fields] OR \"neurally\"[All Fields]"
},
{
"from": "enterochromaffin",
"to": "\"enterochromaffin cells\"[MeSH Terms] OR (\"enterochromaffin\"[All Fields] AND \"cells\"[All Fields]) OR \"enterochromaffin cells\"[All Fields] OR \"enterochromaffin\"[All Fields] OR \"enterochromaffine\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"visceral\"[All Fields] OR \"viscerally\"[All Fields] OR \"hypersensitiv*\"[All Fields] OR (\"brain\"[MeSH Terms] OR \"brain\"[All Fields] OR \"brains\"[All Fields] OR \"brain s\"[All Fields]) OR (\"neural\"[All Fields] OR \"neuralization\"[All Fields] OR \"neuralize\"[All Fields] OR \"neuralized\"[All Fields] OR \"neuralizes\"[All Fields] OR \"neuralizing\"[All Fields] OR \"neurally\"[All Fields]) OR \"genetic*\"[All Fields] OR (\"enterochromaffin cells\"[MeSH Terms] OR (\"enterochromaffin\"[All Fields] AND \"cells\"[All Fields]) OR \"enterochromaffin cells\"[All Fields] OR \"enterochromaffin\"[All Fields] OR \"enterochromaffine\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "microbiome",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (microbiom* OR microbiot* OR probiotic* OR fecal OR faecal OR FMT) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "31",
"retmax": "31",
"retstart": "0",
"idlist": [
"42866695",
"42861963",
"42860924",
"42853311",
"42850871",
"42845202",
"42843366",
"42843354",
"42842449",
"42842008",
"42839967",
"42834635",
"42833252",
"42824924",
"42823900",
"42823420",
"42821694",
"42814405",
"42780104",
"42613095",
"42611412",
"42609157",
"42480795",
"42456784",
"42444523",
"42413530",
"42398186",
"42162772",
"42084579",
"41860116",
"41325894"
],
"translationset": [
{
"from": "fecal",
"to": "\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]"
},
{
"from": "faecal",
"to": "\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]"
},
{
"from": "FMT",
"to": "\"Ferment Technol\"[Journal:__jid101609755] OR \"fmt\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"microbiom*\"[All Fields] OR \"microbiot*\"[All Fields] OR \"probiotic*\"[All Fields] OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"ferment technol\"[Journal] OR \"fmt\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "microbiome",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (microbiom* OR microbiot* OR probiotic* OR fecal OR faecal OR FMT) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "fecal",
"to": "\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]"
},
{
"from": "faecal",
"to": "\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]"
},
{
"from": "FMT",
"to": "\"Ferment Technol\"[Journal:__jid101609755] OR \"fmt\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"microbiom*\"[All Fields] OR \"microbiot*\"[All Fields] OR \"probiotic*\"[All Fields] OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"faecal\"[All Fields] OR \"feces\"[MeSH Terms] OR \"feces\"[All Fields] OR \"fecal\"[All Fields] OR \"faecally\"[All Fields] OR \"fecally\"[All Fields] OR \"fecals\"[All Fields]) OR (\"ferment technol\"[Journal] OR \"fmt\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "post-infectious",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (postinfect* OR post-infect* OR gastroenteritis OR COVID) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "5",
"retmax": "5",
"retstart": "0",
"idlist": [
"42843354",
"42578562",
"42444523",
"42329518",
"42084579"
],
"translationset": [
{
"from": "gastroenteritis",
"to": "\"gastroenteric\"[All Fields] OR \"gastroenteritis\"[MeSH Terms] OR \"gastroenteritis\"[All Fields] OR \"gastroenteritides\"[All Fields]"
},
{
"from": "COVID",
"to": "\"sars-cov-2\"[MeSH Terms] OR \"sars-cov-2\"[All Fields] OR \"covid\"[All Fields] OR \"covid-19\"[MeSH Terms] OR \"covid-19\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"postinfect*\"[All Fields] OR \"post infect*\"[All Fields] OR (\"gastroenteric\"[All Fields] OR \"gastroenteritis\"[MeSH Terms] OR \"gastroenteritis\"[All Fields] OR \"gastroenteritides\"[All Fields]) OR (\"sars cov 2\"[MeSH Terms] OR \"sars cov 2\"[All Fields] OR \"covid\"[All Fields] OR \"covid 19\"[MeSH Terms] OR \"covid 19\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "post-infectious",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (postinfect* OR post-infect* OR gastroenteritis OR COVID) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "gastroenteritis",
"to": "\"gastroenteric\"[All Fields] OR \"gastroenteritis\"[MeSH Terms] OR \"gastroenteritis\"[All Fields] OR \"gastroenteritides\"[All Fields]"
},
{
"from": "COVID",
"to": "\"sars-cov-2\"[MeSH Terms] OR \"sars-cov-2\"[All Fields] OR \"covid\"[All Fields] OR \"covid-19\"[MeSH Terms] OR \"covid-19\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"postinfect*\"[All Fields] OR \"post infect*\"[All Fields] OR (\"gastroenteric\"[All Fields] OR \"gastroenteritis\"[MeSH Terms] OR \"gastroenteritis\"[All Fields] OR \"gastroenteritides\"[All Fields]) OR (\"sars cov 2\"[MeSH Terms] OR \"sars cov 2\"[All Fields] OR \"covid\"[All Fields] OR \"covid 19\"[MeSH Terms] OR \"covid 19\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "diet",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diet* OR FODMAP OR fibre OR fiber OR gluten OR eating disorder*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "23",
"retmax": "23",
"retstart": "0",
"idlist": [
"42861429",
"42860910",
"42854770",
"42842449",
"42842008",
"42838312",
"42834635",
"42833252",
"42823909",
"42823900",
"42823420",
"42819509",
"42816255",
"42814269",
"42580594",
"42572206",
"42477421",
"42413530",
"42374605",
"42329518",
"41882491",
"41325894",
"40974448"
],
"translationset": [
{
"from": "FODMAP",
"to": "\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields]"
},
{
"from": "fibre",
"to": "\"fiber\"[All Fields] OR \"fiber's\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre's\"[All Fields] OR \"fibres\"[All Fields]"
},
{
"from": "fiber",
"to": "\"fiber\"[All Fields] OR \"fiber's\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre's\"[All Fields] OR \"fibres\"[All Fields]"
},
{
"from": "gluten",
"to": "\"gluten's\"[All Fields] OR \"glutens\"[Supplementary Concept] OR \"glutens\"[All Fields] OR \"gluten\"[All Fields] OR \"glutens\"[MeSH Terms]"
},
{
"from": "eating",
"to": "\"eating\"[MeSH Terms] OR \"eating\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diet*\"[All Fields] OR (\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"glutens\"[Supplementary Concept] OR \"glutens\"[All Fields] OR \"gluten\"[All Fields] OR \"glutens\"[MeSH Terms]) OR ((\"eating\"[MeSH Terms] OR \"eating\"[All Fields]) AND \"disorder*\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "diet",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diet* OR FODMAP OR fibre OR fiber OR gluten OR eating disorder*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "FODMAP",
"to": "\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields]"
},
{
"from": "fibre",
"to": "\"fiber\"[All Fields] OR \"fiber's\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre's\"[All Fields] OR \"fibres\"[All Fields]"
},
{
"from": "fiber",
"to": "\"fiber\"[All Fields] OR \"fiber's\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre's\"[All Fields] OR \"fibres\"[All Fields]"
},
{
"from": "gluten",
"to": "\"gluten's\"[All Fields] OR \"glutens\"[Supplementary Concept] OR \"glutens\"[All Fields] OR \"gluten\"[All Fields] OR \"glutens\"[MeSH Terms]"
},
{
"from": "eating",
"to": "\"eating\"[MeSH Terms] OR \"eating\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diet*\"[All Fields] OR (\"fodmap\"[All Fields] OR \"fodmaps\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"fiber\"[All Fields] OR \"fiber s\"[All Fields] OR \"fiberized\"[All Fields] OR \"fibers\"[All Fields] OR \"fibre\"[All Fields] OR \"fibre s\"[All Fields] OR \"fibres\"[All Fields]) OR (\"glutens\"[Supplementary Concept] OR \"glutens\"[All Fields] OR \"gluten\"[All Fields] OR \"glutens\"[MeSH Terms]) OR ((\"eating\"[MeSH Terms] OR \"eating\"[All Fields]) AND \"disorder*\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "antispasmodics",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antispasmodic* OR peppermint OR mebeverine OR otilonium) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "1",
"retmax": "1",
"retstart": "0",
"idlist": [
"42572206"
],
"translationset": [
{
"from": "peppermint",
"to": "\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]"
},
{
"from": "mebeverine",
"to": "\"mebeverine\"[Supplementary Concept] OR \"mebeverine\"[All Fields]"
},
{
"from": "otilonium",
"to": "\"octylonium\"[Supplementary Concept] OR \"octylonium\"[All Fields] OR \"otilonium\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antispasmodic*\"[All Fields] OR (\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]) OR (\"mebeverine\"[Supplementary Concept] OR \"mebeverine\"[All Fields]) OR (\"octylonium\"[Supplementary Concept] OR \"octylonium\"[All Fields] OR \"otilonium\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "antispasmodics",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antispasmodic* OR peppermint OR mebeverine OR otilonium) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "peppermint",
"to": "\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]"
},
{
"from": "mebeverine",
"to": "\"mebeverine\"[Supplementary Concept] OR \"mebeverine\"[All Fields]"
},
{
"from": "otilonium",
"to": "\"octylonium\"[Supplementary Concept] OR \"octylonium\"[All Fields] OR \"otilonium\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antispasmodic*\"[All Fields] OR (\"mentha piperita\"[MeSH Terms] OR (\"mentha\"[All Fields] AND \"piperita\"[All Fields]) OR \"mentha piperita\"[All Fields] OR \"peppermint\"[All Fields]) OR (\"mebeverine\"[Supplementary Concept] OR \"mebeverine\"[All Fields]) OR (\"octylonium\"[Supplementary Concept] OR \"octylonium\"[All Fields] OR \"otilonium\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "ibs-c",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (constipation OR linaclotide OR tenapanor OR lubiprostone OR plecanatide OR secretagogue) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "10",
"retmax": "10",
"retstart": "0",
"idlist": [
"42859374",
"42854770",
"42819509",
"42816255",
"42613095",
"42480795",
"42442754",
"42413530",
"41762189",
"40503810"
],
"translationset": [
{
"from": "constipation",
"to": "\"constipation\"[MeSH Terms] OR \"constipation\"[All Fields] OR \"constipated\"[All Fields] OR \"constipating\"[All Fields] OR \"constipations\"[All Fields]"
},
{
"from": "linaclotide",
"to": "\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields] OR \"linaclotide's\"[All Fields]"
},
{
"from": "tenapanor",
"to": "\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]"
},
{
"from": "lubiprostone",
"to": "\"lubiprostone\"[Supplementary Concept] OR \"lubiprostone\"[All Fields] OR \"lubiprostone\"[MeSH Terms] OR \"lubiprostone's\"[All Fields]"
},
{
"from": "plecanatide",
"to": "\"plecanatide\"[Supplementary Concept] OR \"plecanatide\"[All Fields]"
},
{
"from": "secretagogue",
"to": "\"secretagogues\"[Supplementary Concept] OR \"secretagogues\"[All Fields] OR \"secretagogue\"[All Fields] OR \"secretagogues\"[MeSH Terms]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"constipation\"[MeSH Terms] OR \"constipation\"[All Fields] OR \"constipated\"[All Fields] OR \"constipating\"[All Fields] OR \"constipations\"[All Fields] OR (\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields]) OR (\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]) OR (\"lubiprostone\"[Supplementary Concept] OR \"lubiprostone\"[All Fields] OR \"lubiprostone\"[MeSH Terms]) OR (\"plecanatide\"[Supplementary Concept] OR \"plecanatide\"[All Fields]) OR (\"secretagogues\"[Supplementary Concept] OR \"secretagogues\"[All Fields] OR \"secretagogue\"[All Fields] OR \"secretagogues\"[MeSH Terms])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "ibs-c",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (constipation OR linaclotide OR tenapanor OR lubiprostone OR plecanatide OR secretagogue) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "constipation",
"to": "\"constipation\"[MeSH Terms] OR \"constipation\"[All Fields] OR \"constipated\"[All Fields] OR \"constipating\"[All Fields] OR \"constipations\"[All Fields]"
},
{
"from": "linaclotide",
"to": "\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields] OR \"linaclotide's\"[All Fields]"
},
{
"from": "tenapanor",
"to": "\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]"
},
{
"from": "lubiprostone",
"to": "\"lubiprostone\"[Supplementary Concept] OR \"lubiprostone\"[All Fields] OR \"lubiprostone\"[MeSH Terms] OR \"lubiprostone's\"[All Fields]"
},
{
"from": "plecanatide",
"to": "\"plecanatide\"[Supplementary Concept] OR \"plecanatide\"[All Fields]"
},
{
"from": "secretagogue",
"to": "\"secretagogues\"[Supplementary Concept] OR \"secretagogues\"[All Fields] OR \"secretagogue\"[All Fields] OR \"secretagogues\"[MeSH Terms]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"constipation\"[MeSH Terms] OR \"constipation\"[All Fields] OR \"constipated\"[All Fields] OR \"constipating\"[All Fields] OR \"constipations\"[All Fields] OR (\"linaclotide\"[Supplementary Concept] OR \"linaclotide\"[All Fields]) OR (\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]) OR (\"lubiprostone\"[Supplementary Concept] OR \"lubiprostone\"[All Fields] OR \"lubiprostone\"[MeSH Terms]) OR (\"plecanatide\"[Supplementary Concept] OR \"plecanatide\"[All Fields]) OR (\"secretagogues\"[Supplementary Concept] OR \"secretagogues\"[All Fields] OR \"secretagogue\"[All Fields] OR \"secretagogues\"[MeSH Terms])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "ibs-d",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diarrhea OR diarrhoea OR eluxadoline OR alosetron OR ramosetron OR ondansetron) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "14",
"retmax": "14",
"retstart": "0",
"idlist": [
"42865969",
"42850871",
"42844310",
"42842449",
"42839967",
"42833252",
"42831162",
"42824924",
"42819509",
"42613095",
"42609157",
"42578562",
"42139901",
"40503810"
],
"translationset": [
{
"from": "diarrhea",
"to": "\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]"
},
{
"from": "diarrhoea",
"to": "\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]"
},
{
"from": "eluxadoline",
"to": "\"eluxadoline\"[Supplementary Concept] OR \"eluxadoline\"[All Fields]"
},
{
"from": "alosetron",
"to": "\"alosetron\"[Supplementary Concept] OR \"alosetron\"[All Fields]"
},
{
"from": "ramosetron",
"to": "\"ramosetron\"[Supplementary Concept] OR \"ramosetron\"[All Fields]"
},
{
"from": "ondansetron",
"to": "\"ondansetron\"[Supplementary Concept] OR \"ondansetron\"[All Fields] OR \"ondansetron\"[MeSH Terms] OR \"ondansetrone\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields] OR (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]) OR (\"eluxadoline\"[Supplementary Concept] OR \"eluxadoline\"[All Fields]) OR (\"alosetron\"[Supplementary Concept] OR \"alosetron\"[All Fields]) OR (\"ramosetron\"[Supplementary Concept] OR \"ramosetron\"[All Fields]) OR (\"ondansetron\"[Supplementary Concept] OR \"ondansetron\"[All Fields] OR \"ondansetron\"[MeSH Terms] OR \"ondansetrone\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "ibs-d",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (diarrhea OR diarrhoea OR eluxadoline OR alosetron OR ramosetron OR ondansetron) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "diarrhea",
"to": "\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]"
},
{
"from": "diarrhoea",
"to": "\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]"
},
{
"from": "eluxadoline",
"to": "\"eluxadoline\"[Supplementary Concept] OR \"eluxadoline\"[All Fields]"
},
{
"from": "alosetron",
"to": "\"alosetron\"[Supplementary Concept] OR \"alosetron\"[All Fields]"
},
{
"from": "ramosetron",
"to": "\"ramosetron\"[Supplementary Concept] OR \"ramosetron\"[All Fields]"
},
{
"from": "ondansetron",
"to": "\"ondansetron\"[Supplementary Concept] OR \"ondansetron\"[All Fields] OR \"ondansetron\"[MeSH Terms] OR \"ondansetrone\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields] OR (\"diarrhea\"[MeSH Terms] OR \"diarrhea\"[All Fields] OR \"diarrheas\"[All Fields] OR \"diarrhoea\"[All Fields] OR \"diarrhoeas\"[All Fields]) OR (\"eluxadoline\"[Supplementary Concept] OR \"eluxadoline\"[All Fields]) OR (\"alosetron\"[Supplementary Concept] OR \"alosetron\"[All Fields]) OR (\"ramosetron\"[Supplementary Concept] OR \"ramosetron\"[All Fields]) OR (\"ondansetron\"[Supplementary Concept] OR \"ondansetron\"[All Fields] OR \"ondansetron\"[MeSH Terms] OR \"ondansetrone\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "rifaximin-sibo",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (rifaximin OR SIBO OR bacterial overgrowth OR methane OR methanogen* OR statin) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "4",
"retmax": "4",
"retstart": "0",
"idlist": [
"42850871",
"42816255",
"42609157",
"42580594"
],
"translationset": [
{
"from": "rifaximin",
"to": "\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields]"
},
{
"from": "bacterial",
"to": "\"bacterial\"[All Fields] OR \"bacterially\"[All Fields] OR \"bacterials\"[All Fields]"
},
{
"from": "overgrowth",
"to": "\"overgrowth\"[All Fields] OR \"overgrowths\"[All Fields]"
},
{
"from": "methane",
"to": "\"methanation\"[All Fields] OR \"methane\"[Supplementary Concept] OR \"methane\"[All Fields] OR \"methane\"[MeSH Terms] OR \"methane's\"[All Fields] OR \"methanes\"[All Fields] OR \"methanization\"[All Fields] OR \"methanizer\"[All Fields]"
},
{
"from": "statin",
"to": "\"hydroxymethylglutaryl-coa reductase inhibitors\"[Pharmacological Action] OR \"hydroxymethylglutaryl-coa reductase inhibitors\"[Supplementary Concept] OR \"hydroxymethylglutaryl-coa reductase inhibitors\"[All Fields] OR \"statin\"[All Fields] OR \"hydroxymethylglutaryl-coa reductase inhibitors\"[MeSH Terms] OR (\"hydroxymethylglutaryl-coa\"[All Fields] AND \"reductase\"[All Fields] AND \"inhibitors\"[All Fields]) OR \"statins\"[All Fields] OR \"statin's\"[All Fields] OR \"statine\"[Supplementary Concept] OR \"statine\"[All Fields] OR \"statines\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields] OR \"SIBO\"[All Fields] OR ((\"bacterial\"[All Fields] OR \"bacterially\"[All Fields] OR \"bacterials\"[All Fields]) AND (\"overgrowth\"[All Fields] OR \"overgrowths\"[All Fields])) OR (\"methanation\"[All Fields] OR \"methane\"[Supplementary Concept] OR \"methane\"[All Fields] OR \"methane\"[MeSH Terms] OR \"methane s\"[All Fields] OR \"methanes\"[All Fields] OR \"methanization\"[All Fields] OR \"methanizer\"[All Fields]) OR \"methanogen*\"[All Fields] OR (\"hydroxymethylglutaryl coa reductase inhibitors\"[Pharmacological Action] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[Supplementary Concept] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[All Fields] OR \"statin\"[All Fields] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[MeSH Terms] OR (\"hydroxymethylglutaryl coa\"[All Fields] AND \"reductase\"[All Fields] AND \"inhibitors\"[All Fields]) OR \"statins\"[All Fields] OR \"statin s\"[All Fields] OR \"statine\"[Supplementary Concept] OR \"statine\"[All Fields] OR \"statines\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "rifaximin-sibo",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (rifaximin OR SIBO OR bacterial overgrowth OR methane OR methanogen* OR statin) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "rifaximin",
"to": "\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields]"
},
{
"from": "bacterial",
"to": "\"bacterial\"[All Fields] OR \"bacterially\"[All Fields] OR \"bacterials\"[All Fields]"
},
{
"from": "overgrowth",
"to": "\"overgrowth\"[All Fields] OR \"overgrowths\"[All Fields]"
},
{
"from": "methane",
"to": "\"methanation\"[All Fields] OR \"methane\"[Supplementary Concept] OR \"methane\"[All Fields] OR \"methane\"[MeSH Terms] OR \"methane's\"[All Fields] OR \"methanes\"[All Fields] OR \"methanization\"[All Fields] OR \"methanizer\"[All Fields]"
},
{
"from": "statin",
"to": "\"hydroxymethylglutaryl-coa reductase inhibitors\"[Pharmacological Action] OR \"hydroxymethylglutaryl-coa reductase inhibitors\"[Supplementary Concept] OR \"hydroxymethylglutaryl-coa reductase inhibitors\"[All Fields] OR \"statin\"[All Fields] OR \"hydroxymethylglutaryl-coa reductase inhibitors\"[MeSH Terms] OR (\"hydroxymethylglutaryl-coa\"[All Fields] AND \"reductase\"[All Fields] AND \"inhibitors\"[All Fields]) OR \"statins\"[All Fields] OR \"statin's\"[All Fields] OR \"statine\"[Supplementary Concept] OR \"statine\"[All Fields] OR \"statines\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"rifaximin\"[Supplementary Concept] OR \"rifaximin\"[All Fields] OR \"rifaximin\"[MeSH Terms] OR \"rifaximine\"[All Fields] OR \"SIBO\"[All Fields] OR ((\"bacterial\"[All Fields] OR \"bacterially\"[All Fields] OR \"bacterials\"[All Fields]) AND (\"overgrowth\"[All Fields] OR \"overgrowths\"[All Fields])) OR (\"methanation\"[All Fields] OR \"methane\"[Supplementary Concept] OR \"methane\"[All Fields] OR \"methane\"[MeSH Terms] OR \"methane s\"[All Fields] OR \"methanes\"[All Fields] OR \"methanization\"[All Fields] OR \"methanizer\"[All Fields]) OR \"methanogen*\"[All Fields] OR (\"hydroxymethylglutaryl coa reductase inhibitors\"[Pharmacological Action] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[Supplementary Concept] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[All Fields] OR \"statin\"[All Fields] OR \"hydroxymethylglutaryl coa reductase inhibitors\"[MeSH Terms] OR (\"hydroxymethylglutaryl coa\"[All Fields] AND \"reductase\"[All Fields] AND \"inhibitors\"[All Fields]) OR \"statins\"[All Fields] OR \"statin s\"[All Fields] OR \"statine\"[Supplementary Concept] OR \"statine\"[All Fields] OR \"statines\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "neuromodulators",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antidepress* OR amitriptyline OR neuromodulat* OR pregabalin OR SSRI OR duloxetine) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "4",
"retmax": "4",
"retstart": "0",
"idlist": [
"42844310",
"42704331",
"42084579",
"41762189"
],
"translationset": [
{
"from": "amitriptyline",
"to": "\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline's\"[All Fields]"
},
{
"from": "pregabalin",
"to": "\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin's\"[All Fields]"
},
{
"from": "SSRI",
"to": "\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])"
},
{
"from": "duloxetine",
"to": "\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine's\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antidepress*\"[All Fields] OR (\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline s\"[All Fields]) OR \"neuromodulat*\"[All Fields] OR (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields]) OR (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine s\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "neuromodulators",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (antidepress* OR amitriptyline OR neuromodulat* OR pregabalin OR SSRI OR duloxetine) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "amitriptyline",
"to": "\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline's\"[All Fields]"
},
{
"from": "pregabalin",
"to": "\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin's\"[All Fields]"
},
{
"from": "SSRI",
"to": "\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])"
},
{
"from": "duloxetine",
"to": "\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine's\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"antidepress*\"[All Fields] OR (\"amitriptyline\"[Supplementary Concept] OR \"amitriptyline\"[All Fields] OR \"amitriptylin\"[All Fields] OR \"amitriptyline\"[MeSH Terms] OR \"amitriptyline s\"[All Fields]) OR \"neuromodulat*\"[All Fields] OR (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields]) OR (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine s\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "psychological-therapy",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (psychotherap* OR cognitive behav* OR hypnotherap* OR behavioral OR behavioural) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "19",
"retmax": "19",
"retstart": "0",
"idlist": [
"42861429",
"42860910",
"42844310",
"42838312",
"42837716",
"42824924",
"42823420",
"42818921",
"42816255",
"42814269",
"42641543",
"42517234",
"42504736",
"42473346",
"42329518",
"42190845",
"42150986",
"41895674",
"41325894"
],
"translationset": [
{
"from": "cognitive",
"to": "\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields]"
},
{
"from": "behavioral",
"to": "\"behavior's\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern's\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]"
},
{
"from": "behavioural",
"to": "\"behavior's\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern's\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"psychotherap*\"[All Fields] OR ((\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields]) AND \"behav*\"[All Fields]) OR \"hypnotherap*\"[All Fields] OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]) OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "psychological-therapy",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (psychotherap* OR cognitive behav* OR hypnotherap* OR behavioral OR behavioural) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "cognitive",
"to": "\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields]"
},
{
"from": "behavioral",
"to": "\"behavior's\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern's\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]"
},
{
"from": "behavioural",
"to": "\"behavior's\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern's\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"psychotherap*\"[All Fields] OR ((\"cognition\"[MeSH Terms] OR \"cognition\"[All Fields] OR \"cognitions\"[All Fields] OR \"cognitive\"[All Fields] OR \"cognitively\"[All Fields] OR \"cognitives\"[All Fields]) AND \"behav*\"[All Fields]) OR \"hypnotherap*\"[All Fields] OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields]) OR (\"behavior s\"[All Fields] OR \"behaviorally\"[All Fields] OR \"behaviour\"[All Fields] OR \"behavior\"[MeSH Terms] OR \"behavior\"[All Fields] OR \"behavioural\"[All Fields] OR \"behavioral\"[All Fields] OR \"behaviourally\"[All Fields] OR \"behaviours\"[All Fields] OR \"behaviors\"[All Fields] OR \"pattern\"[All Fields] OR \"pattern s\"[All Fields] OR \"patternability\"[All Fields] OR \"patternable\"[All Fields] OR \"patterned\"[All Fields] OR \"patterning\"[All Fields] OR \"patternings\"[All Fields] OR \"patterns\"[All Fields])) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "placebo-trial-design",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (placebo OR nocebo OR endpoint OR trial design OR label*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "11",
"retmax": "11",
"retstart": "0",
"idlist": [
"42859374",
"42853311",
"42844310",
"42842008",
"42780104",
"42609157",
"42580594",
"42572206",
"42413530",
"42162772",
"42150986"
],
"translationset": [
{
"from": "placebo",
"to": "\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms]"
},
{
"from": "nocebo",
"to": "\"nocebo effect\"[MeSH Terms] OR (\"nocebo\"[All Fields] AND \"effect\"[All Fields]) OR \"nocebo effect\"[All Fields] OR \"nocebo\"[All Fields] OR \"nocebos\"[All Fields]"
},
{
"from": "endpoint",
"to": "\"endpoint\"[All Fields] OR \"endpoints\"[All Fields]"
},
{
"from": "trial",
"to": "\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial's\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]"
},
{
"from": "design",
"to": "\"design\"[All Fields] OR \"design's\"[All Fields] OR \"designabilities\"[All Fields] OR \"designability\"[All Fields] OR \"designable\"[All Fields] OR \"designed\"[All Fields] OR \"designer\"[All Fields] OR \"designer's\"[All Fields] OR \"designers\"[All Fields] OR \"designing\"[All Fields] OR \"designs\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms] OR (\"nocebo effect\"[MeSH Terms] OR (\"nocebo\"[All Fields] AND \"effect\"[All Fields]) OR \"nocebo effect\"[All Fields] OR \"nocebo\"[All Fields] OR \"nocebos\"[All Fields]) OR (\"endpoint\"[All Fields] OR \"endpoints\"[All Fields]) OR ((\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]) AND (\"design\"[All Fields] OR \"design s\"[All Fields] OR \"designabilities\"[All Fields] OR \"designability\"[All Fields] OR \"designable\"[All Fields] OR \"designed\"[All Fields] OR \"designer\"[All Fields] OR \"designer s\"[All Fields] OR \"designers\"[All Fields] OR \"designing\"[All Fields] OR \"designs\"[All Fields])) OR \"label*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "placebo-trial-design",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (placebo OR nocebo OR endpoint OR trial design OR label*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "placebo",
"to": "\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms]"
},
{
"from": "nocebo",
"to": "\"nocebo effect\"[MeSH Terms] OR (\"nocebo\"[All Fields] AND \"effect\"[All Fields]) OR \"nocebo effect\"[All Fields] OR \"nocebo\"[All Fields] OR \"nocebos\"[All Fields]"
},
{
"from": "endpoint",
"to": "\"endpoint\"[All Fields] OR \"endpoints\"[All Fields]"
},
{
"from": "trial",
"to": "\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial's\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]"
},
{
"from": "design",
"to": "\"design\"[All Fields] OR \"design's\"[All Fields] OR \"designabilities\"[All Fields] OR \"designability\"[All Fields] OR \"designable\"[All Fields] OR \"designed\"[All Fields] OR \"designer\"[All Fields] OR \"designer's\"[All Fields] OR \"designers\"[All Fields] OR \"designing\"[All Fields] OR \"designs\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms] OR (\"nocebo effect\"[MeSH Terms] OR (\"nocebo\"[All Fields] AND \"effect\"[All Fields]) OR \"nocebo effect\"[All Fields] OR \"nocebo\"[All Fields] OR \"nocebos\"[All Fields]) OR (\"endpoint\"[All Fields] OR \"endpoints\"[All Fields]) OR ((\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]) AND (\"design\"[All Fields] OR \"design s\"[All Fields] OR \"designabilities\"[All Fields] OR \"designability\"[All Fields] OR \"designable\"[All Fields] OR \"designed\"[All Fields] OR \"designer\"[All Fields] OR \"designer s\"[All Fields] OR \"designers\"[All Fields] OR \"designing\"[All Fields] OR \"designs\"[All Fields])) OR \"label*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "dyspepsia-overlap",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (dyspepsia OR overlap OR comorbid*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "18",
"retmax": "18",
"retstart": "0",
"idlist": [
"42866695",
"42854770",
"42850428",
"42848286",
"42843366",
"42838312",
"42824924",
"42823909",
"42823900",
"42819509",
"42818921",
"42704331",
"42611412",
"42578562",
"42442754",
"42413530",
"42190845",
"42150986"
],
"translationset": [
{
"from": "dyspepsia",
"to": "\"dyspepsia\"[MeSH Terms] OR \"dyspepsia\"[All Fields] OR \"dyspepsias\"[All Fields]"
},
{
"from": "overlap",
"to": "\"overlap\"[All Fields] OR \"overlapped\"[All Fields] OR \"overlapping\"[All Fields] OR \"overlappings\"[All Fields] OR \"overlaps\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"dyspepsia\"[MeSH Terms] OR \"dyspepsia\"[All Fields] OR \"dyspepsias\"[All Fields] OR (\"overlap\"[All Fields] OR \"overlapped\"[All Fields] OR \"overlapping\"[All Fields] OR \"overlappings\"[All Fields] OR \"overlaps\"[All Fields]) OR \"comorbid*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "dyspepsia-overlap",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (dyspepsia OR overlap OR comorbid*) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "dyspepsia",
"to": "\"dyspepsia\"[MeSH Terms] OR \"dyspepsia\"[All Fields] OR \"dyspepsias\"[All Fields]"
},
{
"from": "overlap",
"to": "\"overlap\"[All Fields] OR \"overlapped\"[All Fields] OR \"overlapping\"[All Fields] OR \"overlappings\"[All Fields] OR \"overlaps\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"dyspepsia\"[MeSH Terms] OR \"dyspepsia\"[All Fields] OR \"dyspepsias\"[All Fields] OR (\"overlap\"[All Fields] OR \"overlapped\"[All Fields] OR \"overlapping\"[All Fields] OR \"overlappings\"[All Fields] OR \"overlaps\"[All Fields]) OR \"comorbid*\"[All Fields]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "guidelines",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (guideline[pt] OR practice guideline[pt] OR guideline*[tiab] OR consensus[tiab] OR position paper[tiab]) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "3",
"retmax": "3",
"retstart": "0",
"idlist": [
"42816255",
"42560138",
"40974448"
],
"translationset": [],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"guideline\"[Publication Type] OR \"practice guideline\"[Publication Type] OR \"guideline*\"[Title/Abstract] OR \"consensus\"[Title/Abstract] OR \"position paper\"[Title/Abstract]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "guidelines",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (guideline[pt] OR practice guideline[pt] OR guideline*[tiab] OR consensus[tiab] OR position paper[tiab]) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"guideline\"[Publication Type] OR \"practice guideline\"[Publication Type] OR \"guideline*\"[Title/Abstract] OR \"consensus\"[Title/Abstract] OR \"position paper\"[Title/Abstract]) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
"topic": "patient-experience",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (qualitative OR stigma OR quality of life OR patient experience OR patient reported OR work impairment) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT]))",
"count": "29",
"retmax": "29",
"retstart": "0",
"idlist": [
"42866695",
"42861429",
"42860910",
"42859374",
"42850428",
"42845202",
"42844310",
"42839981",
"42838312",
"42837716",
"42834635",
"42833958",
"42823909",
"42823420",
"42821694",
"42816255",
"42812583",
"42780104",
"42704331",
"42613095",
"42609157",
"42578562",
"42560138",
"42329518",
"42162772",
"42150986",
"41895674",
"41860116",
"41762189"
],
"translationset": [
{
"from": "qualitative",
"to": "\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]"
},
{
"from": "stigma",
"to": "\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma's\"[All Fields]"
},
{
"from": "quality of life",
"to": "\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]"
},
{
"from": "patient",
"to": "\"patient's\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients's\"[All Fields]"
},
{
"from": "experience",
"to": "\"experience\"[All Fields] OR \"experience's\"[All Fields] OR \"experiences\"[All Fields]"
},
{
"from": "reported",
"to": "\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields]"
},
{
"from": "work",
"to": "\"work\"[MeSH Terms] OR \"work\"[All Fields]"
},
{
"from": "impairment",
"to": "\"impair\"[All Fields] OR \"impaired\"[All Fields] OR \"impairement\"[All Fields] OR \"impairements\"[All Fields] OR \"impairing\"[All Fields] OR \"impairment\"[All Fields] OR \"impairments\"[All Fields] OR \"impairs\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields] OR (\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma s\"[All Fields]) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"experience\"[All Fields] OR \"experience s\"[All Fields] OR \"experiences\"[All Fields])) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR ((\"work\"[MeSH Terms] OR \"work\"[All Fields]) AND (\"impair\"[All Fields] OR \"impaired\"[All Fields] OR \"impairement\"[All Fields] OR \"impairements\"[All Fields] OR \"impairing\"[All Fields] OR \"impairment\"[All Fields] OR \"impairments\"[All Fields] OR \"impairs\"[All Fields]))) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])"
},
{
"source": "cochrane",
"topic": "patient-experience",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (qualitative OR stigma OR quality of life OR patient experience OR patient reported OR work impairment) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "qualitative",
"to": "\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]"
},
{
"from": "stigma",
"to": "\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma's\"[All Fields]"
},
{
"from": "quality of life",
"to": "\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]"
},
{
"from": "patient",
"to": "\"patient's\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients's\"[All Fields]"
},
{
"from": "experience",
"to": "\"experience\"[All Fields] OR \"experience's\"[All Fields] OR \"experiences\"[All Fields]"
},
{
"from": "reported",
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},
{
"from": "work",
"to": "\"work\"[MeSH Terms] OR \"work\"[All Fields]"
},
{
"from": "impairment",
"to": "\"impair\"[All Fields] OR \"impaired\"[All Fields] OR \"impairement\"[All Fields] OR \"impairements\"[All Fields] OR \"impairing\"[All Fields] OR \"impairment\"[All Fields] OR \"impairments\"[All Fields] OR \"impairs\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields] OR (\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma s\"[All Fields]) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields]) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"experience\"[All Fields] OR \"experience s\"[All Fields] OR \"experiences\"[All Fields])) OR ((\"patient s\"[All Fields] OR \"patients\"[MeSH Terms] OR \"patients\"[All Fields] OR \"patient\"[All Fields] OR \"patients s\"[All Fields]) AND (\"reportable\"[All Fields] OR \"reporting\"[All Fields] OR \"reportings\"[All Fields] OR \"research report\"[MeSH Terms] OR (\"research\"[All Fields] AND \"report\"[All Fields]) OR \"research report\"[All Fields] OR \"report\"[All Fields] OR \"reported\"[All Fields] OR \"reports\"[All Fields])) OR ((\"work\"[MeSH Terms] OR \"work\"[All Fields]) AND (\"impair\"[All Fields] OR \"impaired\"[All Fields] OR \"impairement\"[All Fields] OR \"impairements\"[All Fields] OR \"impairing\"[All Fields] OR \"impairment\"[All Fields] OR \"impairments\"[All Fields] OR \"impairs\"[All Fields]))) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "pubmed",
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"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "ebastine",
"to": "\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]"
},
{
"from": "virtual",
"to": "\"virtual\"[All Fields] OR \"virtuality\"[All Fields] OR \"virtualization\"[All Fields] OR \"virtualized\"[All Fields] OR \"virtualizing\"[All Fields] OR \"virtuals\"[All Fields]"
},
{
"from": "dietitian",
"to": "\"dietitian's\"[All Fields] OR \"nutritionists\"[MeSH Terms] OR \"nutritionists\"[All Fields] OR \"dietitian\"[All Fields] OR \"dietitians\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"camlipixant\"[All Fields] OR (\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]) OR \"REFIT2\"[All Fields] OR ((\"virtual\"[All Fields] OR \"virtuality\"[All Fields] OR \"virtualization\"[All Fields] OR \"virtualized\"[All Fields] OR \"virtualizing\"[All Fields] OR \"virtuals\"[All Fields]) AND (\"dietitian s\"[All Fields] OR \"nutritionists\"[MeSH Terms] OR \"nutritionists\"[All Fields] OR \"dietitian\"[All Fields] OR \"dietitians\"[All Fields]))) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry])",
"errorlist": {
"phrasesnotfound": [
"brenipatide",
"LY3537031"
],
"fieldsnotfound": []
},
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"source": "cochrane",
"topic": "novel-trials",
"query": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[tiab]) AND (camlipixant OR brenipatide OR LY3537031 OR ebastine OR REFIT2 OR virtual dietitian) AND ((\"2026/09/30\"[PDAT] : \"2026/10/14\"[PDAT]) OR (\"2026/09/30\"[EDAT] : \"2026/10/14\"[EDAT])) AND \"Cochrane Database Syst Rev\"[jour]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "ebastine",
"to": "\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]"
},
{
"from": "virtual",
"to": "\"virtual\"[All Fields] OR \"virtuality\"[All Fields] OR \"virtualization\"[All Fields] OR \"virtualized\"[All Fields] OR \"virtualizing\"[All Fields] OR \"virtuals\"[All Fields]"
},
{
"from": "dietitian",
"to": "\"dietitian's\"[All Fields] OR \"nutritionists\"[MeSH Terms] OR \"nutritionists\"[All Fields] OR \"dietitian\"[All Fields] OR \"dietitians\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR \"irritable bowel\"[Title/Abstract]) AND (\"camlipixant\"[All Fields] OR (\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]) OR \"REFIT2\"[All Fields] OR ((\"virtual\"[All Fields] OR \"virtuality\"[All Fields] OR \"virtualization\"[All Fields] OR \"virtualized\"[All Fields] OR \"virtualizing\"[All Fields] OR \"virtuals\"[All Fields]) AND (\"dietitian s\"[All Fields] OR \"nutritionists\"[MeSH Terms] OR \"nutritionists\"[All Fields] OR \"dietitian\"[All Fields] OR \"dietitians\"[All Fields]))) AND (2026/09/30:2026/10/14[Date - Publication] OR 2026/09/30:2026/10/14[Date - Entry]) AND \"Cochrane Database Syst Rev\"[Journal]",
"errorlist": {
"phrasesnotfound": [
"brenipatide",
"LY3537031"
],
"fieldsnotfound": []
},
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
}
],
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],
"cochrane_summary": {
"topic_searches": 19,
"hits": 0,
"coverage": "CDSR indexed in PubMed only; Cochrane Library and CENTRAL were not searched"
},
"supplemental_pubmed_searches": [
{
"name": "german-guideline-historical",
"query": "(irritable bowel OR Reizdarmsyndrom) AND (Layer OR Andresen) AND (guideline OR Leitlinie) AND 2020:2026[dp]",
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"retmax": "4",
"retstart": "0",
"idlist": [
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],
"translationset": [
{
"from": "irritable bowel",
"to": "\"irritable bowel syndrome\"[MeSH Terms] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields] AND \"syndrome\"[All Fields]) OR \"irritable bowel syndrome\"[All Fields] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields]) OR \"irritable bowel\"[All Fields]"
},
{
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},
{
"from": "guideline",
"to": "\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel syndrome\"[MeSH Terms] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields] AND \"syndrome\"[All Fields]) OR \"irritable bowel syndrome\"[All Fields] OR (\"irritable\"[All Fields] AND \"bowel\"[All Fields]) OR \"irritable bowel\"[All Fields] OR \"Reizdarmsyndrom\"[All Fields]) AND (\"layer\"[All Fields] OR \"layer s\"[All Fields] OR \"layered\"[All Fields] OR \"layering\"[All Fields] OR \"layerings\"[All Fields] OR \"layers\"[All Fields] OR \"Andresen\"[All Fields]) AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR \"Leitlinie\"[All Fields]) AND 2020/01/01:2026/12/31[Date - Publication]"
},
{
"name": "canadian-guideline-historical",
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"count": "5",
"retmax": "5",
"retstart": "0",
"idlist": [
"32010878",
"31526844",
"31294725",
"31294724",
"17464377"
],
"translationset": [
{
"from": "guideline",
"to": "\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields]"
},
{
"from": "consensus",
"to": "\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]"
}
],
"querytranslation": "\"Canadian Association of Gastroenterology\"[All Fields] AND \"irritable bowel syndrome\"[All Fields] AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]))"
},
{
"name": "refit2-followup",
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"idlist": [
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"38151280",
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],
"translationset": [],
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},
{
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{
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},
{
"from": "consensus",
"to": "\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]"
}
],
"querytranslation": "(\"irritable bowel\"[All Fields] OR \"Rome V\"[All Fields]) AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields])) AND 2026/09/30:2026/10/14[Date - Publication]"
},
{
"name": "adult-suicidality",
"query": "\"irritable bowel\" AND (suicid* OR stigma intervention) AND 2026/09/30:2026/10/14[dp]",
"count": "0",
"retmax": "0",
"retstart": "0",
"idlist": [],
"translationset": [
{
"from": "stigma",
"to": "\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma's\"[All Fields]"
},
{
"from": "intervention",
"to": "\"intervention's\"[All Fields] OR \"interventions\"[All Fields] OR \"interventive\"[All Fields] OR \"methods\"[MeSH Terms] OR \"methods\"[All Fields] OR \"intervention\"[All Fields] OR \"interventional\"[All Fields]"
}
],
"querytranslation": "\"irritable bowel\"[All Fields] AND (\"suicid*\"[All Fields] OR ((\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma s\"[All Fields]) AND (\"intervention s\"[All Fields] OR \"interventions\"[All Fields] OR \"interventive\"[All Fields] OR \"methods\"[MeSH Terms] OR \"methods\"[All Fields] OR \"intervention\"[All Fields] OR \"interventional\"[All Fields]))) AND 2026/09/30:2026/10/14[Date - Publication]",
"warninglist": {
"phrasesignored": [],
"quotedphrasesnotfound": [],
"outputmessages": [
"No items found."
]
}
},
{
"name": "criteria-treatment",
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"retmax": "1",
"retstart": "0",
"idlist": [
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],
"translationset": [
{
"from": "subgroup",
"to": "\"subgroup\"[All Fields] OR \"subgrouped\"[All Fields] OR \"subgrouping\"[All Fields] OR \"subgroupings\"[All Fields] OR \"subgroups\"[All Fields]"
},
{
"from": "trial",
"to": "\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial's\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]"
},
{
"from": "treatment",
"to": "\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"treatments\"[All Fields] OR \"therapy\"[Subheading] OR \"therapy\"[All Fields] OR \"treatment\"[All Fields] OR \"treatment's\"[All Fields]"
}
],
"querytranslation": "\"irritable bowel\"[All Fields] AND (\"Rome V\"[All Fields] OR \"Rome IV\"[All Fields]) AND (\"stratif*\"[All Fields] OR (\"subgroup\"[All Fields] OR \"subgrouped\"[All Fields] OR \"subgrouping\"[All Fields] OR \"subgroupings\"[All Fields] OR \"subgroups\"[All Fields])) AND (\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields] OR (\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"treatments\"[All Fields] OR \"therapy\"[MeSH Subheading] OR \"therapy\"[All Fields] OR \"treatment\"[All Fields] OR \"treatment s\"[All Fields])) AND 2026/09/30:2026/10/14[Date - Publication]"
},
{
"name": "pipeline-readouts",
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"idlist": [
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],
"translationset": [
{
"from": "ebastine",
"to": "\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]"
},
{
"from": "tenapanor",
"to": "\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]"
}
],
"querytranslation": "\"irritable bowel\"[All Fields] AND (\"camlipixant\"[All Fields] OR (\"ebastine\"[Supplementary Concept] OR \"ebastine\"[All Fields]) OR (\"tenapanor\"[Supplementary Concept] OR \"tenapanor\"[All Fields]) OR \"virtual dietitian\"[All Fields]) AND 2026/09/30:2026/10/14[Date - Publication]",
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],
"fieldsnotfound": []
}
}
],
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{
"source": "Europe PMC",
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"query": "(\"irritable bowel syndrome\" OR \"irritable bowel\") AND (FIRST_PDATE:[2026-09-30 TO 2026-10-14] OR FIRST_IDATE:[2026-09-30 TO 2026-10-14])",
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"records": [
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},
{
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},
{
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},
{
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},
{
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"title": "Irritable bowel syndrome.",
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"isOpenAccess": "N"
},
{
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"title": "Change in irritable bowel syndrome symptom severity among members of a multi-omic digital food-as-medicine program: a retrospective single-arm cohort study with estimates corrected for regression to the mean",
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"inPMC": "N",
"isOpenAccess": "N"
},
{
"source": "MED",
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"title": "Reply to the comment on \"Prevalence and clinical characteristics of irritable bowel syndrome in Taiwan: Rome III versus Rome IV criteria\".",
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},
{
"source": "MED",
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"title": "When Food Avoidance Meets Compatible Diagnostic Criteria: Avoidant/Restrictive Food Intake Disorder Features in Irritable Bowel Syndrome.",
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},
{
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"title": "Irritable bowel syndrome-like symptoms are associated with increased healthcare utilization in patients with inflammatory bowel disease",
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},
{
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"isOpenAccess": "N"
},
{
"source": "MED",
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"title": "CYP2D6 Metabolizer Status Does Not Predict Response or Tolerability of Low-Dose Nortriptyline for Irritable Bowel Syndrome With Diarrhea. ",
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"isOpenAccess": "Y"
},
{
"source": "MED",
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"title": "Depressive symptoms as a mediator in the association between regular physical activity and irritable bowel syndrome-related symptom severity: a cross-sectional study among college students.",
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"inPMC": "Y",
"isOpenAccess": "Y"
},
{
"source": "MED",
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"doi": "10.1126/science.aeh4468",
"pmcid": null,
"title": "Sex-specific mechanisms of chronic pain.",
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"inPMC": "N",
"isOpenAccess": "N"
},
{
"source": "MED",
"id": "42818921",
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"doi": "10.3389/fphar.2026.1759170",
"pmcid": "PMC13624401",
"title": "Exploring the psychogastroenterology patterns of functional dyspepsia and irritable bowel syndrome comorbidities based on latent profile analysis.",
"firstPublicationDate": "2026-09-16",
"inPMC": "Y",
"isOpenAccess": "Y"
},
{
"source": "PMC",
"id": "PMC13638362",
"pmid": null,
"doi": null,
"pmcid": "PMC13638362",
"title": "Codonopsis pilosula inulin-type fructan CPA ameliorates diarrhea-predominant irritable bowel syndrome via regulation of ER stress-induced autophagy and modulation of gut microbiota",
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"inPMC": "Y",
"isOpenAccess": "Y"
},
{
"source": "PMC",
"id": "PMC13641959",
"pmid": null,
"doi": null,
"pmcid": "PMC13641959",
"title": "Fecal Microbiota Transplantation Beyond Clostridioides difficile Infection: Expanding Indications, Mechanisms, and Future Directions",
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"inPMC": "Y",
"isOpenAccess": "Y"
},
{
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"title": "Personalized Probiotic Treatments for Irritable Bowel Syndrome",
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{
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"title": "Influence of Ear Vagus Nerve Stimulator on Patients With IBS",
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{
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"title": "Probiotic Mixture (L. Rhamnosus GG and L. Plantarum 299V) In Pediatric Irritable Bowel Syndrome",
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{
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"title": "The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms",
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"title": "Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease",
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{
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"title": "Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome",
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"title": "A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)",
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{
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"title": "A Personalized Approach to Abdominal Pain in Irritable Bowel Syndrome",
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"title": "Herbal Supplement (Biocidin REMOVE) for Bacterial Overgrowth in Irritable Bowel Syndrome",
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{
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"title": "A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)",
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{
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"title": "Interactive Effects of Early-Life Stress, Diet, and Metabolism on Gastrointestinal Dysfunction With Neuropsychiatric Symptoms",
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"last_update_posted": "2026-10-01",
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{
"nct_id": "NCT05633706",
"title": "Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis",
"status": "ACTIVE_NOT_RECRUITING",
"last_update_posted": "2026-09-30",
"first_posted": "2022-12-01",
"has_results": false
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],
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"identificationModule": {
"nctId": "NCT07872514",
"orgStudyIdInfo": {
"id": "HiREB#19371"
},
"organization": {
"fullName": "McMaster University",
"class": "OTHER"
},
"briefTitle": "Personalized Probiotic Treatments for Irritable Bowel Syndrome",
"officialTitle": "Deciphering the Role of Bacterial Histamine and Bioactive Phospholipids in IBS: Precision Medicine Pilot Study"
},
"statusModule": {
"statusVerifiedDate": "2026-10",
"overallStatus": "ENROLLING_BY_INVITATION",
"expandedAccessInfo": {
"hasExpandedAccess": false
},
"startDateStruct": {
"date": "2026-10",
"type": "ESTIMATED"
},
"primaryCompletionDateStruct": {
"date": "2028-04-30",
"type": "ESTIMATED"
},
"completionDateStruct": {
"date": "2028-07-30",
"type": "ESTIMATED"
},
"studyFirstSubmitDate": "2026-10-07",
"studyFirstSubmitQcDate": "2026-10-07",
"studyFirstPostDateStruct": {
"date": "2026-10-13",
"type": "ACTUAL"
},
"lastUpdateSubmitDate": "2026-10-07",
"lastUpdatePostDateStruct": {
"date": "2026-10-13",
"type": "ACTUAL"
}
},
"designModule": {
"studyType": "INTERVENTIONAL",
"phases": [
"NA"
],
"designInfo": {
"allocation": "RANDOMIZED",
"interventionModel": "CROSSOVER",
"interventionModelDescription": "N-of-1 trials are single-patient, multiple-period crossover studies in which an individual serves as their own control, cycling through different active treatments and control/placebo phases in randomized order. By eliminating between-subject variability, this design is particularly powerful for conditions with rapid symptom fluctuations, personalized treatment responses, and high baseline heterogeneity, characteristics that make N-of-1 methodology ideally suited for precision medicine. When aggregated across multiple individual trials, N-of-1 results yield population-level estimates statistically equivalent to randomized controlled trial meta-analyses, enabling both individualized therapeutic optimization and generalizable evidence for evidence-based precision interventions.",
"primaryPurpose": "TREATMENT",
"maskingInfo": {
"masking": "DOUBLE",
"maskingDescription": "Principle Investigator and study Coordinators who are in contact with the participants are masked",
"whoMasked": [
"PARTICIPANT",
"INVESTIGATOR"
]
}
},
"enrollmentInfo": {
"count": 30,
"type": "ESTIMATED"
}
},
"armsInterventionsModule": {
"armGroups": [
{
"label": "Probiotic",
"type": "ACTIVE_COMPARATOR",
"description": "Probiotic treatment selected based on the screening results",
"interventionNames": [
"Dietary Supplement: Probiotic containing B longum",
"Dietary Supplement: Probiotic Lactobacillus"
]
},
{
"label": "Placebo",
"type": "PLACEBO_COMPARATOR",
"description": "Capsules similar to treatment containing microcrystalline cellulose",
"interventionNames": [
"Dietary Supplement: Placebo"
]
}
],
"interventions": [
{
"type": "DIETARY_SUPPLEMENT",
"name": "Probiotic containing B longum",
"description": "This probiotic will be used in the group who have higher levels of LPC and LPA",
"armGroupLabels": [
"Probiotic"
]
},
{
"type": "DIETARY_SUPPLEMENT",
"name": "Probiotic Lactobacillus",
"description": "This probiotic will be used in the group who have higher levels of Histamine",
"armGroupLabels": [
"Probiotic"
]
},
{
"type": "DIETARY_SUPPLEMENT",
"name": "Placebo",
"description": "Placebo - microcrystalline cellulose",
"armGroupLabels": [
"Placebo"
]
}
]
},
"outcomesModule": {
"primaryOutcomes": [
{
"measure": "Reduction in abdominal pain",
"description": "The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between \"no pain\" and \"worst pain.\"",
"timeFrame": "Reduction in abdominal pain severity (Visual Analog Scale) comparing probiotic-treatment weeks to placebo-treatment weeks across the 8-week study period."
}
],
"secondaryOutcomes": [
{
"measure": "Improvement in bowel habit satisfaction, bloating, and impact on daily life",
"description": "The visual analog scale (VAS) assessing improvement in bowel habit satisfaction, bloating, and impact on daily life assessed by Visual Analog Scale",
"timeFrame": "Improvement in bowel habit satisfaction, bloating, and impact on daily life (VAS) comparing probiotic-treatment weeks to placebo-treatment weeks across the 8-week study period."
},
{
"measure": "3-month improvement in IBS symptoms",
"description": "To evaluate sustained treatment effects beyond the acute study period, IBS symptom severity will be assessed at 3-month follow-up using the IBS Symptom Severity Scale (IBS-SSS), a validated instrument measuring overall symptom burden. This assessment compares symptom severity at 3 months post-treatment to baseline measurements, providing insight into the durability and longer-term impact of probiotic treatment on IBS symptom trajectory.",
"timeFrame": "Baseline (pre-treatment) to 3-month follow-up (post-intervention)"
},
{
"measure": "3-month improvement in somatization",
"description": "To evaluate the impact of probiotic treatment on psychological symptom manifestation, somatization will be assessed at 3-month follow-up using the Patient Health Questionnaire-15 (PHQ-15), a validated screening instrument measuring somatic symptom burden. This assessment compares somatization scores at 3 months post-treatment to baseline measurements, providing insight into whether probiotic-mediated improvements in gut-brain axis function reduce the psychological distress experienced as physical symptoms.",
"timeFrame": "Baseline (pre-treatment) to 3-month follow-up (post-intervention)"
},
{
"measure": "3-month improvement in anxiety, depression and stress",
"description": "To evaluate the impact of probiotic treatment on psychological well-being, anxiety, depression, and stress will be assessed at 3-month follow-up using the Hospital Anxiety and Depression Scale (HADS) and the Depression Anxiety Stress Scales-21 (DASS-21), validated instruments measuring emotional distress. These assessments compare psychological symptom scores at 3 months post-treatment to baseline measurements, providing insight into whether probiotic-mediated improvements in gut-brain axis function reduce the anxiety, depression, and stress burden commonly associated with IBS.",
"timeFrame": "Baseline (pre-treatment) to 3-month follow-up (post-intervention)"
},
{
"measure": "3-month improvement in Quality of Life",
"description": "To evaluate the broader impact of probiotic treatment on functional well-being, quality of life will be assessed at 3-month follow-up using the IBS Quality of Life Instrument (IBS-QoL), a validated disease-specific measure of health-related quality of life. This assessment compares quality of life scores at 3 months post-treatment to baseline measurements, providing insight into whether probiotic-mediated improvements in IBS symptoms translate into meaningful gains in daily functioning, social engagement, and overall life satisfaction.",
"timeFrame": "Baseline (pre-treatment) to 3-month follow-up (post-intervention)"
}
],
"otherOutcomes": [
{
"measure": "Reduction of stool pro-nociceptive bacterial metabolites by probiotics",
"description": "Reduction of stool levels of pro-nociceptive bacterial metabolites (histamine, LPC/LPA) by probiotics",
"timeFrame": "Reduction in specific bacterial comparing probiotic-treatment weeks to placebo-treatment weeks across the 8-week study period."
}
]
},
"eligibilityModule": {
"eligibilityCriteria": "Inclusion Criteria:\n\n* Diagnosis of Irritable Bowel Syndrome\n* Willing and able to sign written informed consent\n* At least moderate IBS symptoms (IBS-SSS \\>175)\n\nExclusion Criteria:\n\n* Use of antibiotics, antibiotics or probiotics, currently or within the last 4 weeks\n* New IBS treatments (mediations, diet or psychotherapy) started within last 3 months. Medications will be allowed, provided the patient is on a stable dose for more than 3 months.\n* Current organic gastrointestinal or autoimmune diseases, such as type 1 diabetes, celiac disease or inflammatory bowel disease\n* History of major gastrointestinal surgery (bariatric surgery, gastrectomy, colectomy, bowel resection)\n* Connective tissue disease\n* Alcohol or drug abuse\n* Concurrent systemic disease and/or laboratory abnormalities considered by investigators to be a risk or that could interfere with data collection Participation in another dietary or pharmacological treatment study within the last 4 weeks",
"healthyVolunteers": false,
"sex": "ALL",
"minimumAge": "18 Years",
"maximumAge": "70 Years",
"stdAges": [
"ADULT",
"OLDER_ADULT"
]
}
},
"additional_paper_trial": {
"nct_id": "NCT04074421",
"status": "UNKNOWN",
"has_results": false
}
},
"isrctn_query": {
"url": "https://www.isrctn.com/api/query/format/default?q=condition%3A%22irritable+bowel+syndrome%22+AND+lastEdited+GE+2026-09-30T00%3A00%3A00+AND+lastEdited+LE+2026-10-14T23%3A59%3A59&limit=100",
"query": "condition:\"irritable bowel syndrome\" AND lastEdited GE 2026-09-30T00:00:00 AND lastEdited LE 2026-10-14T23:59:59",
"status": 200,
"preview": ""
},
"other_source_retrievals": [
{
"name": "nice",
"url": "https://www.nice.org.uk/guidance/cg61",
"resolved_url": "https://www.nice.org.uk/guidance/cg61",
"status": 200
},
{
"name": "dgvs",
"url": "https://www.dgvs.de/leitlinien/unterer-gi-trakt/reizdarmsyndrom/",
"resolved_url": "https://www.dgvs.de/leitlinien/unterer-gi-trakt/reizdarmsyndrom/",
"status": 200
},
{
"name": "cag",
"url": "https://www.cag-acg.org/clinical-practice-guidelines.html",
"resolved_url": "https://www.cag-acg.org/clinical-practice-guidelines.html",
"status": 404
},
{
"name": "cag-pdf",
"url": "https://www.cag-acg.org/_Library/clinical_cpgs_position_papers/CAG_CPG_for_Management_of_IBS_JCAG_Jan2019.pdf",
"resolved_url": "https://www.cag-acg.org/_Library/clinical_cpgs_position_papers/CAG_CPG_for_Management_of_IBS_JCAG_Jan2019.pdf",
"status": 200
},
{
"name": "acg",
"url": "https://gi.org/guidelines/irritable-bowel-syndrome/",
"resolved_url": "https://gi.org/guidelines/irritable-bowel-syndrome/",
"status": 403
},
{
"name": "aga",
"url": "https://gastro.org/clinical-guidance/pharmacological-management-of-irritable-bowel-syndrome-with-constipation-ibs-c/",
"resolved_url": "https://gastro.org/clinical-guidance/pharmacological-management-of-irritable-bowel-syndrome-with-constipation-ibs-c/",
"status": 403
},
{
"name": "gutsuk",
"url": "https://gutscharity.org.uk/advice-and-information/conditions/irritable-bowel-syndrome/",
"resolved_url": "https://gutscharity.org.uk/advice-and-information/conditions/irritable-bowel-syndrome/",
"status": 403
},
{
"name": "gutsuk-news",
"url": "https://gutscharity.org.uk/news/",
"resolved_url": "https://gutscharity.org.uk/news/",
"status": 403
},
{
"name": "iffgd",
"url": "https://iffgd.org/",
"resolved_url": "https://iffgd.org/",
"status": 403
},
{
"name": "iffgd-trials",
"url": "https://iffgd.org/research/clinical-trials-and-studies/",
"resolved_url": "https://iffgd.org/research/clinical-trials-and-studies/",
"status": 403
},
{
"name": "aboutibs",
"url": "https://aboutibs.org/",
"resolved_url": "https://aboutibs.org/",
"status": 403
},
{
"name": "badgut",
"url": "https://badgut.org/",
"resolved_url": "https://badgut.org/",
"status": 403
},
{
"name": "worldibsday",
"url": "https://worldibsday.org/",
"resolved_url": "https://worldibsday.org/",
"status": 200
},
{
"name": "ibspatient",
"url": "https://www.ibspatient.org/",
"resolved_url": "https://www.ibspatient.org/",
"status": 200
},
{
"name": "pdsb",
"url": "https://www.pdsb.nl/",
"resolved_url": "https://www.pdsb.nl/",
"status": 200
},
{
"name": "magda",
"url": "https://www.magendarm-forum.de/",
"resolved_url": "https://www.magendarm-forum.de/",
"status": 200
},
{
"name": "rome",
"url": "https://theromefoundation.org/",
"resolved_url": "https://theromefoundation.org/",
"status": 200
},
{
"name": "charity-register",
"url": "https://register-of-charities.charitycommission.gov.uk/en/charity-search/-/charity-details/5093293",
"resolved_url": "https://register-of-charities.charitycommission.gov.uk/en/charity-search/-/charity-details/5093293",
"status": 403
},
{
"name": "who-ictrp",
"url": "https://trialsearch.who.int/?query=irritable%20bowel%20syndrome",
"resolved_url": "https://trialsearch.who.int/?query=irritable%20bowel%20syndrome",
"status": 403
},
{
"name": "isrctn",
"url": "https://www.isrctn.com/search?q=irritable+bowel+syndrome",
"resolved_url": "https://www.isrctn.com/holding",
"status": 200
},
{
"name": "anzctr",
"url": "https://www.anzctr.org.au/TrialSearch.aspx?searchTxt=irritable%20bowel%20syndrome&isBasic=True",
"resolved_url": "https://www.anzctr.org.au/TrialSearch.aspx?searchTxt=irritable%20bowel%20syndrome&isBasic=True",
"status": 403
},
{
"name": "ihme",
"url": "https://www.healthdata.org/research-analysis/health-topics/irritable-bowel-syndrome",
"resolved_url": "https://www.healthdata.org/research-analysis/health-topics/irritable-bowel-syndrome",
"status": 404
},
{
"name": "argentina-fulltext",
"url": "https://doi.org/10.1016/j.rgmxen.2026.09.004",
"resolved_url": "https://linkinghub.elsevier.com/retrieve/pii/S2255534X26000721",
"status": 200
},
{
"name": "agomelatine-fulltext",
"url": "https://link.springer.com/article/10.1007/s00210-026-05975-6",
"resolved_url": "https://link.springer.com/article/10.1007/s00210-026-05975-6",
"status": 200
},
{
"name": "irct-trial",
"url": "https://irct.behdasht.gov.ir/trial/80432",
"error": "HTTPSConnectionPool(host='irct.behdasht.gov.ir', port=443): Max retries exceeded with url: /trial/80432 (Caused by ConnectTimeoutError(, 'Connection to irct.behdasht.gov.ir timed out. (connect timeout=45)'))"
},
{
"name": "probiotic-fulltext",
"url": "https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.70672",
"resolved_url": "https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.70672",
"status": 403
},
{
"name": "refit2-fulltext",
"url": "https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01424-8/fulltext",
"resolved_url": "https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01424-8/fulltext",
"status": 403
},
{
"name": "german-doi",
"url": "https://doi.org/10.1055/a-1591-4794",
"resolved_url": "https://www.thieme-connect.de/DOI/DOI?10.1055/a-1591-4794",
"status": 200
},
{
"name": "refit2-elsevier",
"url": "https://api.elsevier.com/content/article/PII:S0140673626014248?httpAccept=text/xml",
"status": 200
},
{
"name": "argentina-elsevier",
"url": "https://api.elsevier.com/content/article/PII:S2255534X26000721?httpAccept=text/xml",
"status": 200
},
{
"name": "PDSB youth research-priority event",
"url": "https://www.pdsb.nl/activiteiten/31-oktober-2026-workshop-pds-onderzoeksagenda-jongeren/",
"status": 200,
"datePublished": "2026-08-23T17:44:59+00:00",
"dateModified": "2026-09-30T16:46:18+00:00",
"event_date": "2026-10-31",
"triage": "patient-voice source added; planned event, not a completed agenda"
}
],
"limitations": [
"WHO ICTRP HTTP 403; ANZCTR challenge/403; Iranian Registry of Clinical Trials record request timed out. No global non-US registry absence is asserted.",
"Cochrane CENTRAL was not searched: Cochrane Library HTTP 403 documented in SOURCES.md.",
"SciELO and LILACS could not be searched (HTTP 403 per SOURCES.md); no absence about regional transportability is asserted.",
"Unpaywall skipped because LIFEBANK_CONTACT_EMAIL was unset; no personal email was read or sent. Crossref used without mailto.",
"REFIT2 publisher full text remained blocked; no secondary or 50-point endpoint was inferred.",
"The CAG library URL requested returned 404, but its official guideline PDF returned 200; the paper full text was also retrieved through Europe PMC.",
"Patient-organisation direct requests and web-tool retrievals have different access outcomes; successful browser/search reads do not mean the blocked programmatic requests succeeded."
],
"web_search_queries": [
"irritable bowel syndrome guideline October 2026 September 2026 society Rome V",
"site.nice.org.uk CG61 irritable bowel syndrome 2026 update",
"site.dgvs.de Reizdarmsyndrom S3 Leitlinie 2026",
"irritable bowel syndrome October 2026 statistics prevalence IFFGD Guts UK",
"site.cag-acg.org irritable bowel syndrome guideline 2026 2019",
"site.iffgd.org \"2026\" \"October\" IBS",
"site.ibspatient.org \"October\" \"2026\"",
"site.badgut.org \"2026\" \"IBS\"",
"\"10.1055/a-1591-4794\"",
"\"Argentine consensus\" \"2026\" \"Soifer\" breath",
"site.healthdata.org \"irritable bowel\" 2026",
"site.pdsb.nl \"31 oktober 2026\""
],
"local_validation": {
"checks": [
"All identifiers in edited markdown appear in live PubMed or ClinicalTrials.gov responses",
"All eight new records have PubMed type and Crossref updated-by checks",
"393 unique bibliography records and all topic counts reconcile",
"Wiki inline citations have local reference entries and reference numbering is consecutive",
"New local links resolve",
"Actual site-builder plan_condition/transform functions recognize and map the exact manifest path",
"Edited wiki frontmatter last-curated is 2026-10-14 and status is draft"
],
"failures": [],
"full_publish_or_strict_site_build": "Not run; publishing handled after this task",
"independent_claim_audit": "Pending a different engine"
}
}