{ "condition": "hypertension", "date": "2026-10-19", "engine": "claude", "window": { "mindate": "2026/10/12", "maxdate": "2026/10/19", "default_datetype": "edat" }, "window_decision": "Entrez date 2026/10/12 to 2026/10/19, from the previous sweep (2026-10-12) to today. Undated queries are marked.", "sources_queried": [ "PubMed E-utilities esearch/esummary/efetch (tool=lifebank, no email, no API key)", "Europe PMC REST search (resultType lite and core)", "ClinicalTrials.gov API v2: all 63 previously cited NCT records, plus query.term searches and a full fetch of NCT05925569", "Crossref works (no mailto) for DOI resolution and updated-by retraction checks", "NICE NG136 HTML page", "WHO hypertension fact sheet HTML page", "Blood Pressure UK news page and World Hypertension League homepage" ], "sources_not_searched": { "cochranelibrary.com": "HTTP 403 on 2026-10-19. CDSR searched via PubMed only; CENTRAL not searched.", "search.scielo.org": "HTTP 403 on 2026-10-19. Not searched.", "LILACS": "Not searched.", "WHO ICTRP": "Not queried (JavaScript portal).", "ANZCTR, CTRI, EU CTR/CTIS, ISRCTN, ChiCTR": "Not queried.", "Unpaywall": "Skipped: LIFEBANK_CONTACT_EMAIL unset.", "Embase, Scopus, Web of Science": "Not available." }, "pubmed": { "broad_majr": { "query": "(hypertension[majr]) AND 2026/10/12:2026/10/19[edat]", "count": 39, "translation": "\"hypertension\"[MeSH Major Topic] AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893848", "42893435", "42892642", "42891596", "42888837", "42888544", "42886978", "42886743", "42885189", "42883820", "42883795", "42883319", "42878893", "42876071", "42875917", "42875603", "42875145", "42873813", "42872749", "42872422", "42871398", "42871064", "42871049", "42870389", "42869458", "42867591", "42867037", "42866566", "42865079", "42864696", "42863998", "42862680", "42862619", "42862427", "42861682", "42861537", "42861003", "42860881", "42860722" ], "topic_term": "hypertension[majr]" }, "broad_ti": { "query": "(hypertension[ti]) AND 2026/10/12:2026/10/19[edat]", "count": 146, "translation": "\"hypertension\"[Title] AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893940", "42893939", "42893435", "42893348", "42893017", "42892951", "42892941", "42892666", "42892652", "42892625", "42891961", "42891596", "42891253", "42890906", "42890473", "42890441", "42890376", "42890010", "42889929", "42889748", "42889141", "42889095", "42888837", "42888530", "42888243", "42888194", "42888193", "42887271", "42886978", "42886743", "42886602", "42886511", "42886510", "42886198", "42886197", "42886155", "42886134", "42885806", "42885738", "42885485", "42885348", "42885189", "42884042", "42883820", "42883795", "42883709", "42883319", "42883275", "42882413", "42882261", "42882238", "42882225", "42882200", "42882128", "42882072", "42881974", "42881891", "42881539", "42881399", "42881321", "42881236", "42880616", "42880263", "42879959", "42879777", "42879357", "42879212", "42879121", "42879106", "42878893", "42878256", "42877973", "42877905", "42877894", "42877822", "42877785", "42877373", "42877306", "42877200", "42877094", "42876665", "42876460", "42876404", "42876376", "42875603", "42875338", "42875145", "42875013", "42873813", "42873412", "42872749", "42872237", "42872129", "42872033", "42871737", "42871695", "42871604", "42871398", "42871216", "42871207", "42871064", "42871049", "42871017", "42870980", "42870389", "42869924", "42869923", "42869921", "42869734", "42869318", "42869242", "42868013", "42866754", "42866566", "42866558", "42866517", "42865918", "42865898", "42865871", "42865079", "42864372", "42864279", "42863998", "42863864", "42863762", "42863704", "42863621", "42863421", "42862695", "42862680", "42862646", "42862427", "42862413", "42861776", "42861767", "42861754", "42861729", "42861682", "42861537", "42861390", "42861216", "42861003", "42860881", "42860744", "42860722", "42860566" ], "topic_term": "hypertension[ti]" }, "high_signal": { "query": "(((hypertension[majr] OR \"blood pressure\"[majr]) AND (practice guideline[pt] OR guideline[pt] OR meta-analysis[pt] OR systematic review[pt] OR randomized controlled trial[pt]))) AND 2026/10/12:2026/10/19[edat]", "count": 2, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"blood pressure\"[MeSH Major Topic]) AND (\"practice guideline\"[Publication Type] OR \"guideline\"[Publication Type] OR \"meta-analysis\"[Publication Type] OR \"systematic review\"[Publication Type] OR \"randomized controlled trial\"[Publication Type]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42885189", "42875917" ], "topic_term": "((hypertension[majr] OR \"blood pressure\"[majr]) AND (practice guideline[pt] OR guideline[pt] OR meta-analysis[pt] OR systematic review[pt] OR randomized controlled trial[pt]))" }, "cochrane": { "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension OR \"blood pressure\" OR antihypertensive)) AND 2026/10/12:2026/10/19[edat]", "count": 2, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertense\"[All Fields] OR \"hypertension\"[MeSH Terms] OR \"hypertension\"[All Fields] OR \"hypertension s\"[All Fields] OR \"hypertensions\"[All Fields] OR \"hypertensive\"[All Fields] OR \"hypertensive s\"[All Fields] OR \"hypertensives\"[All Fields] OR \"blood pressure\"[All Fields] OR (\"antihypertension\"[All Fields] OR \"antihypertensive agents\"[Pharmacological Action] OR \"antihypertensive agents\"[Supplementary Concept] OR \"antihypertensive agents\"[All Fields] OR \"antihypertensive\"[All Fields] OR \"antihypertensive agents\"[MeSH Terms] OR (\"antihypertensive\"[All Fields] AND \"agents\"[All Fields]) OR \"antihypertensives\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42867023", "42861682" ], "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension OR \"blood pressure\" OR antihypertensive)" }, "cochrane_all": { "query": "(\"Cochrane Database Syst Rev\"[jour]) AND 2026/10/12:2026/10/19[edat]", "count": 9, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42886005", "42886002", "42878653", "42878647", "42867023", "42863850", "42861686", "42861682", "42861678" ], "topic_term": "\"Cochrane Database Syst Rev\"[jour]" }, "measurement": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (ambulatory OR \"home blood pressure\" OR cuff OR measurement OR \"white coat\" OR masked OR nocturnal OR validation OR cuffless)) AND 2026/10/12:2026/10/19[edat]", "count": 94, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"ambulatories\"[All Fields] OR \"ambulatory\"[All Fields] OR \"home blood pressure\"[All Fields] OR \"cuff\"[All Fields] OR (\"measurability\"[All Fields] OR \"measurable\"[All Fields] OR \"measurably\"[All Fields] OR \"measure s\"[All Fields] OR \"measureable\"[All Fields] OR \"measured\"[All Fields] OR \"measurement\"[All Fields] OR \"measurement s\"[All Fields] OR \"measurements\"[All Fields] OR \"measurer\"[All Fields] OR \"measurers\"[All Fields] OR \"measuring\"[All Fields] OR \"measurings\"[All Fields] OR \"measurment\"[All Fields] OR \"measurments\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"measure\"[All Fields] OR \"measures\"[All Fields]) OR \"white coat\"[All Fields] OR (\"mask s\"[All Fields] OR \"masked\"[All Fields] OR \"masking\"[All Fields] OR \"masks\"[MeSH Terms] OR \"masks\"[All Fields]) OR (\"nocturnal\"[All Fields] OR \"nocturnality\"[All Fields] OR \"nocturnally\"[All Fields]) OR (\"valid\"[All Fields] OR \"validate\"[All Fields] OR \"validated\"[All Fields] OR \"validates\"[All Fields] OR \"validating\"[All Fields] OR \"validation\"[All Fields] OR \"validational\"[All Fields] OR \"validations\"[All Fields] OR \"validator\"[All Fields] OR \"validators\"[All Fields] OR \"validities\"[All Fields] OR \"validity\"[All Fields]) OR \"cuffless\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893940", "42893017", "42892666", "42892625", "42892584", "42890441", "42890376", "42889948", "42889748", "42889095", "42888852", "42888243", "42888195", "42887526", "42886978", "42886155", "42886134", "42885809", "42885782", "42885485", "42885348", "42885189", "42883820", "42883795", "42883709", "42882413", "42882238", "42882225", "42882200", "42882155", "42882016", "42881955", "42881891", "42881399", "42881321", "42881236", "42880878", "42879959", "42879777", "42879504", "42879121", "42879106", "42878893", "42878396", "42877973", "42877894", "42877785", "42877094", "42876665", "42876404", "42875603", "42875338", "42875145", "42875013", "42874297", "42873412", "42872749", "42872422", "42872033", "42871592", "42871398", "42871216", "42871064", "42871049", "42870980", "42870536", "42870389", "42869923", "42869921", "42869852", "42869458", "42869183", "42867037", "42866680", "42866517", "42865871", "42864716", "42864696", "42864373", "42864372", "42864128", "42863621", "42862646", "42862619", "42862539", "42862413", "42861788", "42861754", "42861455", "42861392", "42861390", "42861216", "42861003", "42860566" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (ambulatory OR \"home blood pressure\" OR cuff OR measurement OR \"white coat\" OR masked OR nocturnal OR validation OR cuffless)" }, "epidemiology": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (prevalence OR awareness OR \"global burden\" OR NCD-RisC OR cascade OR incidence)) AND 2026/10/12:2026/10/19[edat]", "count": 54, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"awareness\"[MeSH Terms] OR \"awareness\"[All Fields] OR \"aware\"[All Fields] OR \"awarenesses\"[All Fields]) OR \"global burden\"[All Fields] OR \"NCD-RisC\"[All Fields] OR (\"cascadability\"[All Fields] OR \"cascadable\"[All Fields] OR \"cascade\"[All Fields] OR \"cascaded\"[All Fields] OR \"cascades\"[All Fields] OR \"cascading\"[All Fields]) OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893848", "42892625", "42891596", "42890473", "42888852", "42888544", "42888530", "42888243", "42886743", "42886511", "42885809", "42885806", "42885682", "42885485", "42883795", "42882413", "42882225", "42879504", "42879357", "42879212", "42878893", "42878256", "42877973", "42877822", "42877094", "42876376", "42875603", "42875013", "42873412", "42872749", "42872422", "42871592", "42871398", "42871207", "42871064", "42871049", "42869923", "42869921", "42869318", "42867037", "42866517", "42865918", "42865623", "42865079", "42864696", "42864373", "42864279", "42863621", "42862646", "42862619", "42861767", "42861754", "42861682", "42861390" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (prevalence OR awareness OR \"global burden\" OR NCD-RisC OR cascade OR incidence)" }, "pathophysiology": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (pathophysiology OR mechanism OR sympathetic OR renin OR sodium OR endothelial OR stiffness OR immune)) AND 2026/10/12:2026/10/19[edat]", "count": 68, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"pathophysiologies\"[All Fields] OR \"physiopathology\"[MeSH Subheading] OR \"physiopathology\"[All Fields] OR \"pathophysiology\"[All Fields] OR (\"mechanism\"[All Fields] OR \"mechanisms\"[All Fields]) OR (\"sympathetic\"[All Fields] OR \"sympathetically\"[All Fields] OR \"sympathetics\"[All Fields]) OR (\"renin\"[Supplementary Concept] OR \"renin\"[All Fields] OR \"renin\"[MeSH Terms] OR \"renins\"[All Fields] OR \"renine\"[All Fields]) OR (\"sodium\"[Supplementary Concept] OR \"sodium\"[All Fields] OR \"sodium\"[MeSH Terms] OR \"sodiums\"[All Fields]) OR (\"endothelialization\"[All Fields] OR \"endothelialize\"[All Fields] OR \"endothelialized\"[All Fields] OR \"endothelializing\"[All Fields] OR \"endothelials\"[All Fields] OR \"endothelium\"[MeSH Terms] OR \"endothelium\"[All Fields] OR \"endothelial\"[All Fields]) OR (\"stiff\"[All Fields] OR \"stiffness\"[All Fields] OR \"stiffnesses\"[All Fields]) OR (\"immune\"[All Fields] OR \"immuned\"[All Fields] OR \"immunes\"[All Fields] OR \"immunisation\"[All Fields] OR \"vaccination\"[MeSH Terms] OR \"vaccination\"[All Fields] OR \"immunization\"[All Fields] OR \"immunization\"[MeSH Terms] OR \"immunisations\"[All Fields] OR \"immunizations\"[All Fields] OR \"immunise\"[All Fields] OR \"immunised\"[All Fields] OR \"immuniser\"[All Fields] OR \"immunisers\"[All Fields] OR \"immunising\"[All Fields] OR \"immunities\"[All Fields] OR \"immunity\"[MeSH Terms] OR \"immunity\"[All Fields] OR \"immunization s\"[All Fields] OR \"immunize\"[All Fields] OR \"immunized\"[All Fields] OR \"immunizer\"[All Fields] OR \"immunizers\"[All Fields] OR \"immunizes\"[All Fields] OR \"immunizing\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893940", "42893848", "42893435", "42893348", "42893017", "42892666", "42892652", "42892642", "42891596", "42890906", "42890473", "42890010", "42889748", "42888837", "42888194", "42888193", "42886510", "42886134", "42886085", "42885782", "42885348", "42885189", "42884042", "42883820", "42883319", "42883275", "42882016", "42881974", "42881891", "42881321", "42880616", "42879212", "42879121", "42879106", "42878893", "42877973", "42877822", "42876460", "42875917", "42873813", "42872749", "42872237", "42870389", "42869949", "42869924", "42869852", "42869458", "42869318", "42867998", "42867591", "42867037", "42866680", "42866566", "42865918", "42865871", "42865079", "42864696", "42864373", "42864372", "42863864", "42863704", "42862619", "42862427", "42862413", "42861776", "42861003", "42860881", "42860722" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (pathophysiology OR mechanism OR sympathetic OR renin OR sodium OR endothelial OR stiffness OR immune)" }, "genetics": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (GWAS OR genome-wide OR polygenic OR Mendelian OR Liddle OR monogenic)) AND 2026/10/12:2026/10/19[edat]", "count": 5, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"genome wide association study\"[MeSH Terms] OR (\"genome-wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields] OR \"genome-wide\"[All Fields] OR (\"polygene\"[All Fields] OR \"polygenes\"[All Fields] OR \"polygenic\"[All Fields] OR \"polygenically\"[All Fields] OR \"polygenicity\"[All Fields]) OR (\"mendelian\"[All Fields] OR \"mendelians\"[All Fields]) OR (\"liddle\"[All Fields] OR \"liddle s\"[All Fields]) OR (\"monogenic\"[All Fields] OR \"monogenically\"[All Fields] OR \"monogenics\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42889095", "42888544", "42882225", "42877973", "42870980" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (GWAS OR genome-wide OR polygenic OR Mendelian OR Liddle OR monogenic)" }, "secondary": { "query": "((\"primary aldosteronism\" OR hyperaldosteronism OR pheochromocytoma OR \"renal artery stenosis\" OR renovascular OR \"fibromuscular dysplasia\" OR (\"secondary hypertension\"))) AND 2026/10/12:2026/10/19[edat]", "count": 30, "translation": "(\"primary aldosteronism\"[All Fields] OR (\"hyperaldosteronism\"[MeSH Terms] OR \"hyperaldosteronism\"[All Fields] OR \"hyperaldosteronisms\"[All Fields]) OR (\"phaeochromocytoma\"[All Fields] OR \"pheochromocytoma\"[MeSH Terms] OR \"pheochromocytoma\"[All Fields] OR \"phaeochromocytomas\"[All Fields] OR \"pheochromocytomas\"[All Fields]) OR \"renal artery stenosis\"[All Fields] OR \"renovascular\"[All Fields] OR \"fibromuscular dysplasia\"[All Fields] OR \"secondary hypertension\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893849", "42889948", "42889765", "42889522", "42889018", "42886353", "42886145", "42886129", "42886065", "42884048", "42882155", "42880592", "42880032", "42878740", "42877914", "42875308", "42874048", "42873233", "42871930", "42871260", "42871030", "42869612", "42866865", "42866661", "42866373", "42866309", "42865698", "42864640", "42864372", "42861275" ], "topic_term": "(\"primary aldosteronism\" OR hyperaldosteronism OR pheochromocytoma OR \"renal artery stenosis\" OR renovascular OR \"fibromuscular dysplasia\" OR (\"secondary hypertension\"))" }, "targets": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (intensive OR target OR SPRINT OR \"J-curve\")) AND 2026/10/12:2026/10/19[edat]", "count": 42, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"intensive\"[All Fields] OR \"intensives\"[All Fields] OR (\"target\"[All Fields] OR \"targetability\"[All Fields] OR \"targetable\"[All Fields] OR \"targeted\"[All Fields] OR \"targeting\"[All Fields] OR \"targetings\"[All Fields] OR \"targets\"[All Fields] OR \"targetted\"[All Fields] OR \"targetting\"[All Fields]) OR (\"sprint\"[All Fields] OR \"sprinted\"[All Fields] OR \"sprinting\"[All Fields] OR \"sprints\"[All Fields]) OR \"J-curve\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893848", "42893435", "42892642", "42891961", "42890473", "42889948", "42888544", "42888530", "42886743", "42886511", "42885485", "42883275", "42882155", "42881955", "42881891", "42881399", "42880616", "42879777", "42879357", "42878893", "42877973", "42876071", "42875603", "42873365", "42872749", "42872237", "42872129", "42872033", "42869923", "42868013", "42867591", "42867037", "42866566", "42865918", "42865623", "42864373", "42863762", "42863704", "42862413", "42861937", "42861682", "42861320" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (intensive OR target OR SPRINT OR \"J-curve\")" }, "lifestyle": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (sodium OR salt OR potassium OR DASH OR diet OR exercise OR alcohol OR weight)) AND 2026/10/12:2026/10/19[edat]", "count": 47, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"sodium\"[Supplementary Concept] OR \"sodium\"[All Fields] OR \"sodium\"[MeSH Terms] OR \"sodiums\"[All Fields] OR (\"sodium chloride\"[Supplementary Concept] OR \"sodium chloride\"[All Fields] OR \"salt\"[All Fields] OR \"sodium chloride\"[MeSH Terms] OR (\"sodium\"[All Fields] AND \"chloride\"[All Fields])) OR (\"potassium dietary\"[Supplementary Concept] OR \"potassium dietary\"[All Fields] OR \"potassium\"[All Fields] OR \"potassium\"[Supplementary Concept] OR \"potassium, dietary\"[MeSH Terms] OR (\"potassium\"[All Fields] AND \"dietary\"[All Fields]) OR \"dietary potassium\"[All Fields] OR \"potassium\"[MeSH Terms]) OR \"DASH\"[All Fields] OR (\"diet\"[MeSH Terms] OR \"diet\"[All Fields]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"alcohol s\"[All Fields] OR \"alcoholate\"[All Fields] OR \"alcoholates\"[All Fields] OR \"alcohols\"[Supplementary Concept] OR \"alcohols\"[All Fields] OR \"alcohols\"[MeSH Terms] OR \"ethanol\"[Supplementary Concept] OR \"ethanol\"[All Fields] OR \"alcohol\"[All Fields] OR \"ethanol\"[MeSH Terms]) OR (\"weight s\"[All Fields] OR \"weighted\"[All Fields] OR \"weighting\"[All Fields] OR \"weightings\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"weight\"[All Fields] OR \"body weight\"[MeSH Terms] OR (\"body\"[All Fields] AND \"weight\"[All Fields]) OR \"body weight\"[All Fields] OR \"weights\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893435", "42892652", "42892642", "42891961", "42891596", "42891253", "42890473", "42890376", "42888852", "42888544", "42888194", "42888193", "42887271", "42886743", "42885782", "42883795", "42882238", "42879959", "42878893", "42878256", "42877822", "42877200", "42876460", "42875917", "42873813", "42871592", "42871398", "42871207", "42871064", "42871049", "42870980", "42869852", "42869318", "42867998", "42866566", "42866517", "42865079", "42864372", "42863421", "42862646", "42862619", "42861788", "42861392", "42861390", "42861003", "42860881", "42860744" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (sodium OR salt OR potassium OR DASH OR diet OR exercise OR alcohol OR weight)" }, "drugs": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (amlodipine OR thiazide OR chlorthalidone OR indapamide OR ACE OR ARB OR \"single-pill\" OR polypill OR combination OR chronotherapy OR bedtime)) AND 2026/10/12:2026/10/19[edat]", "count": 30, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"amlodipin\"[All Fields] OR \"amlodipine\"[Supplementary Concept] OR \"amlodipine\"[All Fields] OR \"amlodipine\"[MeSH Terms] OR \"amlodipine s\"[All Fields] OR (\"thiazid\"[All Fields] OR \"thiazides\"[Supplementary Concept] OR \"thiazides\"[All Fields] OR \"thiazide\"[All Fields] OR \"thiazides\"[MeSH Terms] OR \"thiazidic\"[All Fields]) OR (\"chlorthalidone\"[Supplementary Concept] OR \"chlorthalidone\"[All Fields] OR \"chlorthalidone\"[MeSH Terms]) OR (\"indapamide\"[Supplementary Concept] OR \"indapamide\"[All Fields] OR \"indapamid\"[All Fields] OR \"indapamide\"[MeSH Terms]) OR (\"avian conserv ecol\"[Journal] OR \"ann clin epidemiol\"[Journal] OR \"ann cancer epidemiol\"[Journal] OR \"ace\"[All Fields]) OR \"ARB\"[All Fields] OR \"single-pill\"[All Fields] OR (\"polypill\"[All Fields] OR \"polypills\"[All Fields]) OR (\"combinable\"[All Fields] OR \"combinated\"[All Fields] OR \"combination\"[All Fields] OR \"combinational\"[All Fields] OR \"combinations\"[All Fields] OR \"combinative\"[All Fields] OR \"combine\"[All Fields] OR \"combined\"[All Fields] OR \"combines\"[All Fields] OR \"combining\"[All Fields]) OR (\"chronotherapy\"[MeSH Terms] OR \"chronotherapy\"[All Fields] OR \"chronotherapies\"[All Fields]) OR (\"bedtime\"[All Fields] OR \"bedtimes\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893848", "42891596", "42891090", "42890441", "42889929", "42887526", "42886134", "42882200", "42882128", "42881955", "42881539", "42879959", "42879777", "42879357", "42879106", "42877094", "42876376", "42875013", "42872033", "42870980", "42869948", "42867037", "42865918", "42864373", "42862413", "42861788", "42861767", "42861537", "42860881", "42860722" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (amlodipine OR thiazide OR chlorthalidone OR indapamide OR ACE OR ARB OR \"single-pill\" OR polypill OR combination OR chronotherapy OR bedtime)" }, "new_drugs": { "query": "((baxdrostat OR lorundrostat OR dexfadrostat OR zilebesiran OR aprocitentan OR \"aldosterone synthase inhibitor\" OR vicadrostat)) AND 2026/10/12:2026/10/19[edat]", "count": 1, "translation": "(\"baxdrostat\"[Supplementary Concept] OR \"baxdrostat\"[All Fields] OR \"lorundrostat\"[All Fields] OR \"dexfadrostat\"[All Fields] OR \"zilebesiran\"[All Fields] OR (\"aprocitentan\"[Supplementary Concept] OR \"aprocitentan\"[All Fields]) OR \"aldosterone synthase inhibitor\"[All Fields] OR \"vicadrostat\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42873316" ], "topic_term": "(baxdrostat OR lorundrostat OR dexfadrostat OR zilebesiran OR aprocitentan OR \"aldosterone synthase inhibitor\" OR vicadrostat)" }, "resistant": { "query": "((resistant hypertension OR refractory hypertension OR spironolactone[ti] AND hypertension)) AND 2026/10/12:2026/10/19[edat]", "count": 17, "translation": "(\"hypertension resistant to conventional therapy\"[Supplementary Concept] OR \"hypertension resistant to conventional therapy\"[All Fields] OR \"resistant hypertension\"[All Fields] OR ((\"refractories\"[All Fields] OR \"refractoriness\"[All Fields] OR \"refractory\"[All Fields]) AND (\"hypertense\"[All Fields] OR \"hypertension\"[MeSH Terms] OR \"hypertension\"[All Fields] OR \"hypertension s\"[All Fields] OR \"hypertensions\"[All Fields] OR \"hypertensive\"[All Fields] OR \"hypertensive s\"[All Fields] OR \"hypertensives\"[All Fields])) OR \"spironolactone\"[Title]) AND (\"hypertense\"[All Fields] OR \"hypertension\"[MeSH Terms] OR \"hypertension\"[All Fields] OR \"hypertension s\"[All Fields] OR \"hypertensions\"[All Fields] OR \"hypertensive\"[All Fields] OR \"hypertensive s\"[All Fields] OR \"hypertensives\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893097", "42890979", "42890441", "42889948", "42886978", "42886134", "42882065", "42876404", "42875417", "42872749", "42871111", "42871058", "42867544", "42866558", "42864880", "42864279", "42860793" ], "topic_term": "(resistant hypertension OR refractory hypertension OR spironolactone[ti] AND hypertension)" }, "devices": { "query": "((\"renal denervation\" OR \"baroreflex activation\" OR ultrasound denervation)) AND 2026/10/12:2026/10/19[edat]", "count": 10, "translation": "(\"renal denervation\"[All Fields] OR \"baroreflex activation\"[All Fields] OR ((\"diagnostic imaging\"[MeSH Subheading] OR (\"diagnostic\"[All Fields] AND \"imaging\"[All Fields]) OR \"diagnostic imaging\"[All Fields] OR \"ultrasound\"[All Fields] OR \"ultrasonography\"[MeSH Terms] OR \"ultrasonography\"[All Fields] OR \"ultrasonics\"[MeSH Terms] OR \"ultrasonics\"[All Fields] OR \"ultrasounds\"[All Fields] OR \"ultrasound s\"[All Fields]) AND (\"denervate\"[All Fields] OR \"denervated\"[All Fields] OR \"denervates\"[All Fields] OR \"denervating\"[All Fields] OR \"denervation\"[MeSH Terms] OR \"denervation\"[All Fields] OR \"denervations\"[All Fields] OR \"denerved\"[All Fields]))) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42889948", "42886134", "42877893", "42876404", "42874095", "42873284", "42871156", "42867098", "42866140", "42862674" ], "topic_term": "(\"renal denervation\" OR \"baroreflex activation\" OR ultrasound denervation)" }, "pregnancy": { "query": "((preeclampsia OR pre-eclampsia OR \"gestational hypertension\" OR \"hypertensive disorders of pregnancy\" OR (pregnancy AND hypertension[majr]))) AND 2026/10/12:2026/10/19[edat]", "count": 78, "translation": "(\"pre eclampsia\"[MeSH Terms] OR \"pre eclampsia\"[All Fields] OR \"preeclampsia\"[All Fields] OR (\"pre eclampsia\"[MeSH Terms] OR \"pre eclampsia\"[All Fields] OR (\"pre\"[All Fields] AND \"eclampsia\"[All Fields]) OR \"pre eclampsia\"[All Fields]) OR \"gestational hypertension\"[All Fields] OR \"hypertensive disorders of pregnancy\"[All Fields] OR ((\"pregnancy\"[MeSH Terms] OR \"pregnancy\"[All Fields] OR \"pregnancies\"[All Fields] OR \"pregnancy s\"[All Fields]) AND \"hypertension\"[MeSH Major Topic])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893936", "42893220", "42892777", "42892130", "42892104", "42890979", "42890505", "42889349", "42889217", "42889195", "42888852", "42887928", "42887566", "42887456", "42887427", "42887039", "42887038", "42886667", "42886525", "42886186", "42885485", "42885085", "42883820", "42882516", "42882388", "42882343", "42882236", "42881117", "42881014", "42880760", "42880750", "42880365", "42880270", "42880025", "42879741", "42879397", "42879382", "42879212", "42879077", "42877563", "42876071", "42875917", "42875537", "42875483", "42875059", "42874344", "42874028", "42873649", "42872568", "42872422", "42872265", "42871659", "42871335", "42871049", "42869597", "42869354", "42869196", "42869067", "42868627", "42867801", "42867037", "42866866", "42866662", "42866566", "42866327", "42866308", "42865923", "42865338", "42864211", "42864185", "42863812", "42863735", "42863649", "42862619", "42862500", "42861912", "42861844", "42861660" ], "topic_term": "(preeclampsia OR pre-eclampsia OR \"gestational hypertension\" OR \"hypertensive disorders of pregnancy\" OR (pregnancy AND hypertension[majr]))" }, "special_pops": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (\"chronic kidney disease\" OR diabetes OR frail OR older OR elderly OR children OR adolescents OR Black OR deprescribing)) AND 2026/10/12:2026/10/19[edat]", "count": 86, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"chronic kidney disease\"[All Fields] OR (\"diabete\"[All Fields] OR \"diabetes mellitus\"[MeSH Terms] OR (\"diabetes\"[All Fields] AND \"mellitus\"[All Fields]) OR \"diabetes mellitus\"[All Fields] OR \"diabetes\"[All Fields] OR \"diabetes insipidus\"[MeSH Terms] OR (\"diabetes\"[All Fields] AND \"insipidus\"[All Fields]) OR \"diabetes insipidus\"[All Fields] OR \"diabetic\"[All Fields] OR \"diabetics\"[All Fields] OR \"diabets\"[All Fields]) OR (\"frail\"[All Fields] OR \"frails\"[All Fields] OR \"frailty\"[MeSH Terms] OR \"frailty\"[All Fields] OR \"frailness\"[All Fields]) OR (\"older\"[All Fields] OR \"olders\"[All Fields]) OR (\"aged\"[MeSH Terms] OR \"aged\"[All Fields] OR \"elderly\"[All Fields] OR \"elderlies\"[All Fields] OR \"elderly s\"[All Fields] OR \"elderlys\"[All Fields]) OR (\"child\"[MeSH Terms] OR \"child\"[All Fields] OR \"children\"[All Fields] OR \"child s\"[All Fields] OR \"children s\"[All Fields] OR \"childrens\"[All Fields] OR \"childs\"[All Fields]) OR (\"adolescences\"[All Fields] OR \"adolescency\"[All Fields] OR \"adolescent\"[MeSH Terms] OR \"adolescent\"[All Fields] OR \"adolescence\"[All Fields] OR \"adolescents\"[All Fields] OR \"adolescent s\"[All Fields]) OR (\"black or african american\"[MeSH Terms] OR (\"black\"[All Fields] AND \"or\"[All Fields] AND \"african\"[All Fields] AND \"american\"[All Fields]) OR \"black or african american\"[All Fields] OR \"blacks\"[All Fields] OR \"black people\"[MeSH Terms] OR (\"black\"[All Fields] AND \"people\"[All Fields]) OR \"black people\"[All Fields] OR \"black\"[All Fields] OR \"blackness\"[All Fields]) OR (\"deprescribe\"[All Fields] OR \"deprescribed\"[All Fields] OR \"deprescriptions\"[MeSH Terms] OR \"deprescriptions\"[All Fields] OR \"deprescribing\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893940", "42893939", "42893848", "42892652", "42892625", "42891596", "42890473", "42890010", "42889948", "42889929", "42889748", "42889141", "42888852", "42888544", "42888530", "42888381", "42888192", "42887526", "42887271", "42886743", "42886602", "42886511", "42886134", "42885809", "42885738", "42885682", "42885348", "42885189", "42884042", "42883820", "42883709", "42882413", "42882238", "42882200", "42882155", "42882128", "42881236", "42879959", "42879777", "42879357", "42879106", "42878893", "42878256", "42877822", "42876460", "42876071", "42875917", "42875603", "42875145", "42875013", "42872749", "42872422", "42872129", "42871398", "42871064", "42870536", "42870389", "42869948", "42869923", "42869921", "42869458", "42869183", "42867998", "42866754", "42866680", "42866517", "42865871", "42865623", "42865079", "42864716", "42864696", "42864372", "42863864", "42862646", "42862619", "42862427", "42861937", "42861754", "42861729", "42861682", "42861390", "42861320", "42861003", "42860744", "42860722", "42860566" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (\"chronic kidney disease\" OR diabetes OR frail OR older OR elderly OR children OR adolescents OR Black OR deprescribing)" }, "implementation": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (adherence OR implementation OR \"team-based\" OR pharmacist OR \"community health worker\" OR telemonitoring OR digital OR task-sharing)) AND 2026/10/12:2026/10/19[edat]", "count": 33, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"adherance\"[All Fields] OR \"adhere\"[All Fields] OR \"adhered\"[All Fields] OR \"adherence\"[All Fields] OR \"adherences\"[All Fields] OR \"adherent\"[All Fields] OR \"adherents\"[All Fields] OR \"adherer\"[All Fields] OR \"adherers\"[All Fields] OR \"adheres\"[All Fields] OR \"adhering\"[All Fields] OR (\"implementability\"[All Fields] OR \"implementable\"[All Fields] OR \"implementation\"[All Fields] OR \"implementation s\"[All Fields] OR \"implementational\"[All Fields] OR \"implementations\"[All Fields] OR \"implementer\"[All Fields] OR \"implementers\"[All Fields] OR \"implemention\"[All Fields]) OR \"team-based\"[All Fields] OR (\"pharmacist s\"[All Fields] OR \"pharmacists\"[MeSH Terms] OR \"pharmacists\"[All Fields] OR \"pharmacist\"[All Fields]) OR \"community health worker\"[All Fields] OR (\"telemonitor\"[All Fields] OR \"telemonitored\"[All Fields] OR \"telemonitoring\"[All Fields] OR \"telemonitors\"[All Fields]) OR (\"digitalisation\"[All Fields] OR \"digitalised\"[All Fields] OR \"digitalization\"[All Fields] OR \"digitalize\"[All Fields] OR \"digitalized\"[All Fields] OR \"digitalizer\"[All Fields] OR \"digitalizing\"[All Fields] OR \"digitally\"[All Fields] OR \"digitals\"[All Fields] OR \"digitization\"[All Fields] OR \"digitizations\"[All Fields] OR \"digitize\"[All Fields] OR \"digitized\"[All Fields] OR \"digitizer\"[All Fields] OR \"digitizers\"[All Fields] OR \"digitizes\"[All Fields] OR \"digitizing\"[All Fields] OR \"radiographic image enhancement\"[MeSH Terms] OR (\"radiographic\"[All Fields] AND \"image\"[All Fields] AND \"enhancement\"[All Fields]) OR \"radiographic image enhancement\"[All Fields] OR \"digital\"[All Fields]) OR \"task-sharing\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42890376", "42889141", "42886602", "42885806", "42885189", "42884042", "42882225", "42881974", "42881539", "42881399", "42881236", "42879777", "42879106", "42878396", "42878256", "42876460", "42876376", "42876071", "42873412", "42871737", "42871695", "42871049", "42869924", "42866566", "42866517", "42864716", "42863421", "42862539", "42861937", "42861392", "42861390", "42861216", "42861003" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (adherence OR implementation OR \"team-based\" OR pharmacist OR \"community health worker\" OR telemonitoring OR digital OR task-sharing)" }, "emergencies": { "query": "((\"hypertensive emergency\" OR \"hypertensive urgency\" OR \"malignant hypertension\" OR \"hypertensive crisis\" OR \"severe inpatient hypertension\" OR \"asymptomatic elevated blood pressure\")) AND 2026/10/12:2026/10/19[edat]", "count": 12, "translation": "(\"hypertensive emergency\"[All Fields] OR \"hypertensive urgency\"[All Fields] OR \"malignant hypertension\"[All Fields] OR \"hypertensive crisis\"[All Fields] OR ((\"sever\"[All Fields] OR \"severe\"[All Fields] OR \"severed\"[All Fields] OR \"severely\"[All Fields] OR \"severer\"[All Fields] OR \"severes\"[All Fields] OR \"severing\"[All Fields] OR \"severities\"[All Fields] OR \"severity\"[All Fields] OR \"severs\"[All Fields]) AND (\"inpatient s\"[All Fields] OR \"inpatients\"[MeSH Terms] OR \"inpatients\"[All Fields] OR \"inpatient\"[All Fields]) AND (\"hypertense\"[All Fields] OR \"hypertension\"[MeSH Terms] OR \"hypertension\"[All Fields] OR \"hypertension s\"[All Fields] OR \"hypertensions\"[All Fields] OR \"hypertensive\"[All Fields] OR \"hypertensive s\"[All Fields] OR \"hypertensives\"[All Fields])) OR \"asymptomatic elevated blood pressure\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893013", "42886400", "42880937", "42875308", "42874048", "42873237", "42871604", "42871058", "42866662", "42865249", "42864659", "42862110" ], "topic_term": "(\"hypertensive emergency\" OR \"hypertensive urgency\" OR \"malignant hypertension\" OR \"hypertensive crisis\" OR \"severe inpatient hypertension\" OR \"asymptomatic elevated blood pressure\")" }, "guidelines": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (guideline OR consensus OR \"position paper\" OR \"scientific statement\" OR recommendation)) AND 2026/10/12:2026/10/19[edat]", "count": 22, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]) OR \"position paper\"[All Fields] OR \"scientific statement\"[All Fields] OR (\"recommend\"[All Fields] OR \"recommendable\"[All Fields] OR \"recommendation\"[All Fields] OR \"recommendation s\"[All Fields] OR \"recommendations\"[All Fields] OR \"recommended\"[All Fields] OR \"recommending\"[All Fields] OR \"recommends\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42893017", "42891961", "42888381", "42886602", "42885806", "42882128", "42878396", "42875917", "42873412", "42872749", "42871592", "42869183", "42868013", "42867591", "42865871", "42865623", "42864716", "42862646", "42862310", "42861937", "42861390", "42861320" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (guideline OR consensus OR \"position paper\" OR \"scientific statement\" OR recommendation)" }, "patient_experience": { "query": "((hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (qualitative OR \"patient experience\" OR \"lived experience\" OR stigma OR \"patient-reported\")) AND 2026/10/12:2026/10/19[edat]", "count": 5, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"antihypertensive\"[Title]) AND (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields] OR \"patient experience\"[All Fields] OR \"lived experience\"[All Fields] OR (\"social stigma\"[MeSH Terms] OR (\"social\"[All Fields] AND \"stigma\"[All Fields]) OR \"social stigma\"[All Fields] OR \"stigma\"[All Fields] OR \"stigmas\"[All Fields] OR \"stigma s\"[All Fields]) OR \"patient-reported\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42889141", "42882413", "42881399", "42871695", "42863421" ], "topic_term": "(hypertension[majr] OR hypertension[ti] OR \"blood pressure\"[ti] OR antihypertensive[ti]) AND (qualitative OR \"patient experience\" OR \"lived experience\" OR stigma OR \"patient-reported\")" }, "retraction": { "query": "((hypertension OR \"blood pressure\") AND (retracted publication[pt] OR retraction of publication[pt] OR expression of concern[pt] OR published erratum[pt])) AND 2026/10/12:2026/10/19[edat]", "count": 5, "translation": "(\"hypertense\"[All Fields] OR \"hypertension\"[MeSH Terms] OR \"hypertension\"[All Fields] OR \"hypertension s\"[All Fields] OR \"hypertensions\"[All Fields] OR \"hypertensive\"[All Fields] OR \"hypertensive s\"[All Fields] OR \"hypertensives\"[All Fields] OR \"blood pressure\"[All Fields]) AND (\"retracted publication\"[Publication Type] OR \"expression of concern\"[Publication Type] OR \"published erratum\"[Publication Type]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42892941", "42891901", "42885311", "42877200", "42864185" ], "topic_term": "(hypertension OR \"blood pressure\") AND (retracted publication[pt] OR retraction of publication[pt] OR expression of concern[pt] OR published erratum[pt])" }, "cdsr_pregnancy": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (preeclampsia OR pre-eclampsia OR pregnancy OR postpartum) AND 2026/10/12:2026/10/19[edat]", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"pre eclampsia\"[MeSH Terms] OR \"pre eclampsia\"[All Fields] OR \"preeclampsia\"[All Fields] OR (\"pre eclampsia\"[MeSH Terms] OR \"pre eclampsia\"[All Fields] OR (\"pre\"[All Fields] AND \"eclampsia\"[All Fields]) OR \"pre eclampsia\"[All Fields]) OR (\"pregnancy\"[MeSH Terms] OR \"pregnancy\"[All Fields] OR \"pregnancies\"[All Fields] OR \"pregnancy s\"[All Fields]) OR (\"postpartum period\"[MeSH Terms] OR (\"postpartum\"[All Fields] AND \"period\"[All Fields]) OR \"postpartum period\"[All Fields] OR \"postpartum\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [] }, "cdsr_secondary": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (aldosteronism OR pheochromocytoma OR renovascular OR \"sleep apnoea\" OR \"sleep apnea\") AND 2026/10/12:2026/10/19[edat]", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"aldosteron\"[All Fields] OR \"aldosterone\"[Supplementary Concept] OR \"aldosterone\"[All Fields] OR \"aldosterone\"[MeSH Terms] OR \"aldosterone s\"[All Fields] OR \"aldosterones\"[All Fields] OR \"hyperaldosteronism\"[MeSH Terms] OR \"hyperaldosteronism\"[All Fields] OR \"aldosteronism\"[All Fields] OR (\"phaeochromocytoma\"[All Fields] OR \"pheochromocytoma\"[MeSH Terms] OR \"pheochromocytoma\"[All Fields] OR \"phaeochromocytomas\"[All Fields] OR \"pheochromocytomas\"[All Fields]) OR \"renovascular\"[All Fields] OR \"sleep apnoea\"[All Fields] OR \"sleep apnea\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [] }, "cdsr_devices": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (denervation OR baroreflex) AND 2026/10/12:2026/10/19[edat]", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"denervate\"[All Fields] OR \"denervated\"[All Fields] OR \"denervates\"[All Fields] OR \"denervating\"[All Fields] OR \"denervation\"[MeSH Terms] OR \"denervation\"[All Fields] OR \"denervations\"[All Fields] OR \"denerved\"[All Fields] OR (\"baroreflex\"[MeSH Terms] OR \"baroreflex\"[All Fields] OR \"baroreflexes\"[All Fields] OR \"baroreflexive\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [] }, "cdsr_lifestyle": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (sodium OR salt OR potassium OR diet OR exercise OR alcohol) AND 2026/10/12:2026/10/19[edat]", "count": 1, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"sodium\"[Supplementary Concept] OR \"sodium\"[All Fields] OR \"sodium\"[MeSH Terms] OR \"sodiums\"[All Fields] OR (\"sodium chloride\"[Supplementary Concept] OR \"sodium chloride\"[All Fields] OR \"salt\"[All Fields] OR \"sodium chloride\"[MeSH Terms] OR (\"sodium\"[All Fields] AND \"chloride\"[All Fields])) OR (\"potassium dietary\"[Supplementary Concept] OR \"potassium dietary\"[All Fields] OR \"potassium\"[All Fields] OR \"potassium\"[Supplementary Concept] OR \"potassium, dietary\"[MeSH Terms] OR (\"potassium\"[All Fields] AND \"dietary\"[All Fields]) OR \"dietary potassium\"[All Fields] OR \"potassium\"[MeSH Terms]) OR (\"diet\"[MeSH Terms] OR \"diet\"[All Fields]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"alcohol s\"[All Fields] OR \"alcoholate\"[All Fields] OR \"alcoholates\"[All Fields] OR \"alcohols\"[Supplementary Concept] OR \"alcohols\"[All Fields] OR \"alcohols\"[MeSH Terms] OR \"ethanol\"[Supplementary Concept] OR \"ethanol\"[All Fields] OR \"alcohol\"[All Fields] OR \"ethanol\"[MeSH Terms])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42886005" ] }, "cdsr_implementation": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (adherence OR pharmacist OR \"community health worker\" OR telemonitoring OR self-monitoring) AND 2026/10/12:2026/10/19[edat]", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"adherance\"[All Fields] OR \"adhere\"[All Fields] OR \"adhered\"[All Fields] OR \"adherence\"[All Fields] OR \"adherences\"[All Fields] OR \"adherent\"[All Fields] OR \"adherents\"[All Fields] OR \"adherer\"[All Fields] OR \"adherers\"[All Fields] OR \"adheres\"[All Fields] OR \"adhering\"[All Fields] OR (\"pharmacist s\"[All Fields] OR \"pharmacists\"[MeSH Terms] OR \"pharmacists\"[All Fields] OR \"pharmacist\"[All Fields]) OR \"community health worker\"[All Fields] OR (\"telemonitor\"[All Fields] OR \"telemonitored\"[All Fields] OR \"telemonitoring\"[All Fields] OR \"telemonitors\"[All Fields]) OR \"self-monitoring\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [] }, "cdsr_drugs": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (antihypertensive OR diuretic OR thiazide OR \"calcium channel\" OR \"angiotensin\" OR \"beta-blocker\" OR spironolactone) AND 2026/10/12:2026/10/19[edat]", "count": 1, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"antihypertension\"[All Fields] OR \"antihypertensive agents\"[Pharmacological Action] OR \"antihypertensive agents\"[Supplementary Concept] OR \"antihypertensive agents\"[All Fields] OR \"antihypertensive\"[All Fields] OR \"antihypertensive agents\"[MeSH Terms] OR (\"antihypertensive\"[All Fields] AND \"agents\"[All Fields]) OR \"antihypertensives\"[All Fields] OR (\"diuretics\"[Pharmacological Action] OR \"diuretics\"[Supplementary Concept] OR \"diuretics\"[All Fields] OR \"diuretic\"[All Fields] OR \"diuretics\"[MeSH Terms]) OR (\"thiazid\"[All Fields] OR \"thiazides\"[Supplementary Concept] OR \"thiazides\"[All Fields] OR \"thiazide\"[All Fields] OR \"thiazides\"[MeSH Terms] OR \"thiazidic\"[All Fields]) OR \"calcium channel\"[All Fields] OR \"angiotensin\"[All Fields] OR \"beta-blocker\"[All Fields] OR (\"spironolacton\"[All Fields] OR \"spironolactone\"[Supplementary Concept] OR \"spironolactone\"[All Fields] OR \"spironolactone\"[MeSH Terms] OR \"spironolactone s\"[All Fields] OR \"spironolactones\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42861682" ] }, "cdsr_special": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (kidney OR diabetes OR frail OR elderly OR deprescribing OR children) AND 2026/10/12:2026/10/19[edat]", "count": 3, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"kidney\"[MeSH Terms] OR \"kidney\"[All Fields] OR \"kidneys\"[All Fields] OR \"kidney s\"[All Fields] OR (\"diabete\"[All Fields] OR \"diabetes mellitus\"[MeSH Terms] OR (\"diabetes\"[All Fields] AND \"mellitus\"[All Fields]) OR \"diabetes mellitus\"[All Fields] OR \"diabetes\"[All Fields] OR \"diabetes insipidus\"[MeSH Terms] OR (\"diabetes\"[All Fields] AND \"insipidus\"[All Fields]) OR \"diabetes insipidus\"[All Fields] OR \"diabetic\"[All Fields] OR \"diabetics\"[All Fields] OR \"diabets\"[All Fields]) OR (\"frail\"[All Fields] OR \"frails\"[All Fields] OR \"frailty\"[MeSH Terms] OR \"frailty\"[All Fields] OR \"frailness\"[All Fields]) OR (\"aged\"[MeSH Terms] OR \"aged\"[All Fields] OR \"elderly\"[All Fields] OR \"elderlies\"[All Fields] OR \"elderly s\"[All Fields] OR \"elderlys\"[All Fields]) OR (\"deprescribe\"[All Fields] OR \"deprescribed\"[All Fields] OR \"deprescriptions\"[MeSH Terms] OR \"deprescriptions\"[All Fields] OR \"deprescribing\"[All Fields]) OR (\"child\"[MeSH Terms] OR \"child\"[All Fields] OR \"children\"[All Fields] OR \"child s\"[All Fields] OR \"children s\"[All Fields] OR \"childrens\"[All Fields] OR \"childs\"[All Fields])) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [ "42886002", "42867023", "42863850" ] }, "cdsr_emergency": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (\"hypertensive emergency\" OR \"hypertensive urgency\" OR \"hypertensive crisis\") AND 2026/10/12:2026/10/19[edat]", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertensive emergency\"[All Fields] OR \"hypertensive urgency\"[All Fields] OR \"hypertensive crisis\"[All Fields]) AND 2026/10/12:2026/10/19[Date - Entry]", "pmids_returned": [] }, "pubmed_dateless_guard_pdat": { "query": "(hypertension[majr]) AND (practice guideline[pt] OR guideline[pt]) AND 2026/10/01:2026/10/19[dp]", "count": 1, "translation": "\"hypertension\"[MeSH Major Topic] AND (\"practice guideline\"[Publication Type] OR \"guideline\"[Publication Type]) AND 2026/10/01:2026/10/19[Date - Publication]", "pmids_returned": [ "42554264" ] }, "variability_trials": { "query": "((\"blood pressure variability\"[tiab] OR \"visit-to-visit\"[tiab]) AND (randomized controlled trial[pt] OR randomi*[ti] OR trial[ti])) AND 2026/10/12:2026/10/19[edat]", "count": 0, "pmids_returned": [] }, "alert_pa_results": { "query": "(ALERT-PA[tiab] OR NCT05925569[si] OR NCT05925569[tiab] OR (primary aldosteronism[ti] AND (alert[tiab] OR \"decision support\"[tiab])))", "count": 10, "pmids_returned": [ "42789196", "42697927", "41645899", "41419178", "40704808", "39473879", "38679387", "29895075", "21369868", "20387576" ], "note": "No ALERT-PA results paper among the returned records (titles checked by esummary). Undated query." } }, "unique_pmids_summarised": [ "42860566", "42860722", "42860744", "42860793", "42860881", "42861003", "42861216", "42861275", "42861320", "42861390", "42861392", "42861455", "42861537", "42861660", "42861678", "42861682", "42861686", "42861729", "42861754", "42861767", "42861776", "42861788", "42861844", "42861912", "42861937", "42862110", "42862310", "42862413", "42862427", "42862500", "42862539", "42862619", "42862646", "42862674", "42862680", "42862695", "42863421", "42863621", "42863649", "42863704", "42863735", "42863762", "42863812", "42863850", "42863864", "42863998", "42864128", "42864185", "42864211", "42864279", "42864372", "42864373", "42864640", "42864659", "42864696", "42864716", "42864880", "42865079", "42865249", "42865338", "42865623", "42865698", "42865871", "42865898", "42865918", "42865923", "42866140", "42866308", "42866309", "42866327", "42866373", "42866517", "42866558", "42866566", "42866661", "42866662", "42866680", "42866754", "42866865", "42866866", "42867023", "42867037", "42867098", "42867544", "42867591", "42867801", "42867998", "42868013", "42868627", "42869067", "42869183", "42869196", "42869242", "42869318", "42869354", "42869458", "42869597", "42869612", "42869734", "42869852", "42869921", "42869923", "42869924", "42869948", "42869949", "42870389", "42870536", "42870980", "42871017", "42871030", "42871049", "42871058", "42871064", "42871111", "42871156", "42871207", "42871216", "42871260", "42871335", "42871398", "42871592", "42871604", "42871659", "42871695", "42871737", "42871930", "42872033", "42872129", "42872237", "42872265", "42872422", "42872568", "42872749", "42873233", "42873237", "42873284", "42873316", "42873365", "42873412", "42873649", "42873813", "42874028", "42874048", "42874095", "42874297", "42874344", "42875013", "42875059", "42875145", "42875308", "42875338", "42875417", "42875483", "42875537", "42875603", "42875917", "42876071", "42876376", "42876404", "42876460", "42876665", "42877094", "42877200", "42877306", "42877373", "42877563", "42877785", "42877822", "42877893", "42877894", "42877905", "42877914", "42877973", "42878256", "42878396", "42878647", "42878653", "42878740", "42878893", "42879077", "42879106", "42879121", "42879212", "42879357", "42879382", "42879397", "42879504", "42879741", "42879777", "42879959", "42880025", "42880032", "42880263", "42880270", "42880365", "42880592", "42880616", "42880750", "42880760", "42880878", "42880937", "42881014", "42881117", "42881236", "42881321", "42881399", "42881539", "42881891", "42881955", "42881974", "42882016", "42882065", "42882072", "42882128", "42882155", "42882200", "42882225", "42882236", "42882238", "42882261", "42882343", "42882388", "42882413", "42882516", "42883275", "42883319", "42883709", "42883795", "42883820", "42884042", "42884048", "42885085", "42885189", "42885311", "42885348", "42885485", "42885682", "42885738", "42885782", "42885806", "42885809", "42886002", "42886005", "42886065", "42886085", "42886129", "42886134", "42886145", "42886155", "42886186", "42886197", "42886198", "42886353", "42886400", "42886510", "42886511", "42886525", "42886602", "42886667", "42886743", "42886978", "42887038", "42887039", "42887271", "42887427", "42887456", "42887526", "42887566", "42887928", "42888192", "42888193", "42888194", "42888195", "42888243", "42888381", "42888530", "42888544", "42888837", "42888852", "42889018", "42889095", "42889141", "42889195", "42889217", "42889349", "42889522", "42889748", "42889765", "42889929", "42889948", "42890010", "42890376", "42890441", "42890473", "42890505", "42890906", "42890979", "42891090", "42891253", "42891596", "42891901", "42891961", "42892104", "42892130", "42892584", "42892625", "42892642", "42892652", "42892666", "42892777", "42892941", "42892951", "42893013", "42893017", "42893097", "42893220", "42893348", "42893435", "42893848", "42893849", "42893936", "42893939", "42893940" ], "unique_pmid_count": 323, "europe_pmc": { "broad": { "query": "(TITLE:\"hypertension\" OR TITLE:\"blood pressure\") AND FIRST_PDATE:[2026-10-12 TO 2026-10-19] AND (PUB_TYPE:\"practice guideline\" OR PUB_TYPE:\"systematic review\" OR PUB_TYPE:\"meta-analysis\" OR PUB_TYPE:\"randomized controlled trial\")", "hitCount": 1, "returned": [ { "id": "PMC13658899", "source": "PMC", "pmid": null, "doi": null, "title": "Prevalence and factors associated with pulmonary hypertension in patients undergoing maintenance hemodialysis: a systematic review and meta-analysis", "isOpenAccess": "Y" } ] }, "cochrane": { "query": "JOURNAL:\"Cochrane Database Syst Rev\" AND (TITLE:\"hypertension\" OR TITLE:\"blood pressure\" OR ABSTRACT:\"hypertension\") AND FIRST_PDATE:[2026-10-12 TO 2026-10-19]", "hitCount": 0, "returned": [] }, "nonmed": { "query": "(TITLE:\"hypertension\" OR TITLE:\"blood pressure\" OR TITLE:\"renal denervation\" OR TITLE:\"primary aldosteronism\" OR TITLE:baxdrostat OR TITLE:zilebesiran OR TITLE:lorundrostat) AND FIRST_PDATE:[2026-10-12 TO 2026-10-19] AND NOT (SRC:MED)", "hitCount": 32, "returned": [ { "id": "PMC13658453", "source": "PMC", "pmid": null, "doi": null, "title": "Trajectory-based associations between a structured acupressure protocol, blood pressure variability, and autonomic balance in patients with primary hypertension", "isOpenAccess": "Y" }, { "id": "PPR1340642", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10895368/v1", "title": "Blood pressure improvement and long-term outcomes after carotid stenting in patients with hypertension and atherosclerotic carotid stenosis", "isOpenAccess": "N" }, { "id": "PPR1342507", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.12.26365335", "title": "Blood Pressure and Heart Rate Stationarity in Predicting TEVAR Response", "isOpenAccess": "N" }, { "id": "PPR1343082", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10940453/v1", "title": "Seasonal variation in blood pressure reactivity to stress tests in young adults", "isOpenAccess": "N" }, { "id": "PMC13657270", "source": "PMC", "pmid": null, "doi": null, "title": "Association of the Triglyceride–Glucose Index with Systolic and Diastolic Blood Pressure Among Patients With Type 2 Diabetes Mellitus", "isOpenAccess": "Y" }, { "id": "PPR1344123", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.13.26365387", "title": "Spatial variation and correlates of raised blood pressure in Cambodia: a Gaussian-process geostatistical analysis of the 2023 STEPwise survey", "isOpenAccess": "N" }, { "id": "PPR1342602", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.11.26365219", "title": "Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study", "isOpenAccess": "N" }, { "id": "PPR1342202", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.13.26365389", "title": "Dietary Intake, Handgrip Strength and Elevated Blood Pressure Among Community-Dwelling Older Adults in Peri-Urban Ghana: A Cross-sectional Study", "isOpenAccess": "N" }, { "id": "PPR1339146", "source": "PPR", "pmid": null, "doi": "10.12688/openreseurope.22702.1", "title": "Health services intervention integrating HTN and HIV care improves long-term blood pressure control among people living with HIV in Uganda", "isOpenAccess": "N" }, { "id": "PMC13661318", "source": "PMC", "pmid": null, "doi": null, "title": "Multimodal evaluation and etiology-oriented management of chronic intracranial venous hypertension", "isOpenAccess": "Y" }, { "id": "PPR1344136", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.14.26365441", "title": "Risk Factors for Hypertension in the Western Highlands of Rural Guatemala", "isOpenAccess": "N" }, { "id": "PMC13661173", "source": "PMC", "pmid": null, "doi": null, "title": "Innovative pharmacist-led hypertension management in urgent care: Bridging the gaps in cardiovascular disease", "isOpenAccess": "N" }, { "id": "PMC13658134", "source": "PMC", "pmid": null, "doi": null, "title": "Beyond pulmonary arterial hypertension: sotatercept across the advanced heart failure and transplant continuum", "isOpenAccess": "Y" }, { "id": "PPR1341540", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10837286/v1", "title": "Mapping hypertension prevalence and absolute burden across the states and districts of India", "isOpenAccess": "N" }, { "id": "PMC13658583", "source": "PMC", "pmid": null, "doi": null, "title": "Population burden of diabetes, hypertension, and cardiovascular disease attributable to obesity: a community-based study in Türkiye", "isOpenAccess": "Y" }, { "id": "PMC13661351", "source": "PMC", "pmid": null, "doi": null, "title": "Interocular symmetry of retinal and choroidal OCT parameters in precapillary pulmonary hypertension: a brief research report", "isOpenAccess": "Y" }, { "id": "PMC13662907", "source": "PMC", "pmid": null, "doi": null, "title": "Beyond detection: developing probabilistic hemodynamic phenotyping after a positive point-of-care pulmonary hypertension test", "isOpenAccess": "Y" }, { "id": "PMC13658083", "source": "PMC", "pmid": null, "doi": null, "title": "High-fat diet and portal hypertension: a triangulation approach combining Mendelian randomization with retrospective clinical analysis", "isOpenAccess": "Y" }, { "id": "PMC13658899", "source": "PMC", "pmid": null, "doi": null, "title": "Prevalence and factors associated with pulmonary hypertension in patients undergoing maintenance hemodialysis: a systematic review and meta-analysis", "isOpenAccess": "Y" }, { "id": "PMC13657995", "source": "PMC", "pmid": null, "doi": null, "title": "The associations between dynapenic obesity and cognitive disorder in older hypertension patients: a multicenter cross-sectional study", "isOpenAccess": "Y" }, { "id": "PPR1340517", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-11222315/v1", "title": "Baroreflex sensitivity as a target for nonpharmacological interventions in elderly patients with supine hypertension and orthostatic hypotension", "isOpenAccess": "N" }, { "id": "PPR1339540", "source": "PPR", "pmid": null, "doi": "10.20944/preprints202610.1185.v1", "title": "Circulating miRNA Signatures in Preeclampsia: Potential Biomarkers for Differentiating Preeclampsia from Gestational Hypertension", "isOpenAccess": "N" }, { "id": "PMC13655641", "source": "PMC", "pmid": null, "doi": null, "title": "Unlocking the Potential of Nutritional Approaches and Bioactive Compounds to Modulate Oxidative Stress and Inflammation in Systemic Arterial Hypertension", "isOpenAccess": "Y" }, { "id": "PPR1341578", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10457378/v1", "title": "Social participation diversity and cognitive trajectories in older adults with hypertension and diabetes: a longitudinal cohort study", "isOpenAccess": "N" }, { "id": "PMC13663875", "source": "PMC", "pmid": null, "doi": null, "title": "Correction: Associations between various obesity-related indicators and hypertension: a national cross-sectional survey with 117,609 Chinese adults", "isOpenAccess": "Y" }, { "id": "PMC13656009", "source": "PMC", "pmid": null, "doi": null, "title": "Pressure-flow discordance in perioperative pulmonary hypertension: a mechanism-based review and provisional five-domain right-heart model for noncardiac surgery", "isOpenAccess": "Y" }, { "id": "PPR1340549", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10037337/v1", "title": "Alcohol Intake Amplifies the Association Between Triglyceride–Cholesterol–Body Weight Index (TCBI) and Incident Hypertension: A Nationwide Cohort Study", "isOpenAccess": "N" }, { "id": "PPR1342479", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.12.26365325", "title": "Feasibility of continuous finger arterial pressure recording with synchronised facial video in a hypertension clinic cohort: the BP-WAVE pilot study", "isOpenAccess": "N" }, { "id": "PPR1343057", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10767244/v1", "title": "Association between psychosocial distress and a history of cardiovascular events among adults with hypertension in the SAVA Region, Madagascar : a multicenter cross-sectional study", "isOpenAccess": "N" }, { "id": "PPR1343062", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10883609/v1", "title": "Five-Year Real-World Outcomes of iStent inject W® Combined with Phacoemulsification in Ocular Hypertension and Primary Open-Angle Glaucoma", "isOpenAccess": "N" }, { "id": "PMC13654592", "source": "PMC", "pmid": null, "doi": null, "title": "Association Between Aerobic Physical Activity and Hypertension Among U.S. Adults: A Cross-Sectional Analysis of NHANES (National Health and Nutrition Examination Survey) 2021-2023", "isOpenAccess": "Y" }, { "id": "PPR1341549", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10857622/v1", "title": "Effectiveness of Nursing Interventional Package on Vascular Symptoms, Quality Of Life and Perinatal Outcome among Pregnant Women with Pregnancy Induced Hypertension: A Pilot Interventional Study", "isOpenAccess": "N" } ] }, "guideline_title": { "query": "(TITLE:\"hypertension\" OR TITLE:\"blood pressure\") AND (TITLE:guideline OR TITLE:consensus OR TITLE:\"position paper\" OR TITLE:\"scientific statement\") AND FIRST_PDATE:[2026-10-12 TO 2026-10-19]", "hitCount": 0, "returned": [] }, "ish_africa": { "query": "TITLE:\"guidelines for the management of hypertension in Africa\"", "hitCount": 1, "returned": [ { "id": "42554264", "source": "MED", "pmid": "42554264", "doi": "10.1097/hjh.0000000000004411", "title": "2026 ISH guidelines for the management of hypertension in Africa: the International Society of Hypertension (ISH) African Regional Advisory Group and the Pan African Society of Cardiology (PASCAR).", "isOpenAccess": "N" } ] }, "acc_pathway": { "query": "TITLE:\"resistant hypertension\" AND (TITLE:\"decision pathway\" OR TITLE:\"expert consensus\") AND FIRST_PDATE:[2026-01-01 TO 2026-10-19]", "hitCount": 1, "returned": [ { "id": "42831847", "source": "MED", "pmid": "42831847", "doi": "10.1016/j.jacc.2026.08.028", "title": "Optimizing Blood Pressure Care in Patients With Resistant Hypertension: 2026 ACC Expert Consensus Decision Pathway: A Report of the American College of Cardiology Solution Set Oversight Committee.", "isOpenAccess": "N" } ] }, "new_drugs": { "query": "(baxdrostat OR lorundrostat OR zilebesiran OR aprocitentan OR vicadrostat) AND FIRST_PDATE:[2026-10-12 TO 2026-10-19]", "hitCount": 0, "returned": [] } }, "europe_pmc_followup": { "doi:10.12688/openreseurope.22702.1": "Okello et al., integrated HIV/HTN cluster trial, Uganda. Europe PMC source PPR (preprint). Abstract reports a within-intervention-arm change only (control 3.6% to 36.7%). Not InterCARE. Not added. Crossref updated-by empty." }, "retraction_checks": { "42861682": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1002/14651858.CD016397", "http": 200, "crossref_title": "Blood pressure targets in adults with hypertension", "updated_by": [] } }, "42885806": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1161/JAHA.125.047824", "http": 200, "crossref_title": "Global Prevalence of Adherence to Antihypertensives and Associated Moderating Factors Amon", "updated_by": [] } }, "42886602": { "pubmed_pubtypes": [ "Journal Article", "Review" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1177/15305627261497215", "http": 200, "crossref_title": "Telehealth and Digital Interventions for Type 2 Diabetes and Hypertension in Latin America", "updated_by": [] } }, "42888381": { "pubmed_pubtypes": [ "Journal Article", "Systematic Review" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1007/s40266-026-01342-5", "http": 200, "crossref_title": "Planned Antihypertensive Deprescribing in Long-Term Care Residents: A Systematic Review of", "updated_by": [] } }, "42865623": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1093/ckj/sfag296", "http": 200, "crossref_title": "Achieved systolic blood pressure and cardiovascular outcomes in advanced chronic kidney di", "updated_by": [] } }, "42864372": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1038/s41371-026-01245-3", "http": 200, "crossref_title": "Potential under-recognition of primary aldosteronism in young adults with hypertension", "updated_by": [] } }, "42866865": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1161/HYPERTENSIONAHA.126.27798", "http": 200, "crossref_title": "Aldosterone-Producing Lesions Harboring\n ATP1A1\n ", "updated_by": [] } }, "42887271": { "pubmed_pubtypes": [ "Journal Article", "Review" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1016/j.maturitas.2026.109132", "http": 200, "crossref_title": "Optimal exercise modalities and doses for blood pressure management in adults with prehype", "updated_by": [] } }, "42872422": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1136/bmjmed-2026-003035", "http": 200, "crossref_title": "Pregnancy complications and risk of cardiometabolic-renal conditions in 1.4 million women ", "updated_by": [] } }, "42888852": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1111/1471-0528.70341", "http": 200, "crossref_title": "Postpartum Blood Pressure After Hypertensive Disorders of Pregnancy and Subsequent Cardiov", "updated_by": [] } }, "42872749": { "pubmed_pubtypes": [ "Journal Article", "Observational Study" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1080/08037051.2026.2749134", "http": 200, "crossref_title": "Epidemiology of uncontrolled and treatment‑resistant hypertension: a registry‑based observ", "updated_by": [] } }, "42869921": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1038/s41440-026-02812-4", "http": 200, "crossref_title": "Hypertension detection, treatment and control in young adults in Australia", "updated_by": [] } }, "42861788": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1097/HJH.0000000000004413", "http": 200, "crossref_title": "Twenty-four-hour mean blood pressure and variability combined improve the prognostic value", "updated_by": [] } }, "42885348": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1093/eurjpc/zwag527", "http": 200, "crossref_title": "Effect of Colchicine on Arterial Stiffness in Patients With Hypertension: The COlchicine H", "updated_by": [] } }, "42882155": { "pubmed_pubtypes": [ "Journal Article", "Review" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.3390/jcm15197694", "http": 200, "crossref_title": "Blood Pressure-Lowering Effects of Finerenone: A Systematic Review and Meta-Analysis of Ra", "updated_by": [] } }, "42885485": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1111/1471-0528.70349", "http": 200, "crossref_title": "Prediction of 10‐Year Incident Hypertension After Pregnancy: A Population‐Based Cohort Stu", "updated_by": [] } }, "42886511": { "pubmed_pubtypes": [ "Journal Article" ], "pubmed_comment_flags": [], "crossref": { "doi": "10.1080/14737167.2026.2751401", "http": 200, "crossref_title": "Cost-utility of expanded hypertension screening and treatment among adults covered by Peru", "updated_by": [] } } }, "added_pmids": [ "42861682", "42885806", "42886602", "42888381", "42865623", "42864372", "42866865", "42887271", "42872422", "42888852", "42872749", "42869921", "42861788", "42885348", "42882155", "42885485", "42886511" ], "clinicaltrials": { "rechecked_2026_10_19": [ { "nct": "NCT01534299", "title": "Global SYMPLICITY Registry (GSR) DEFINE", "status": "RECRUITING", "last_update": "2026-04-27", "results_first": null, "primary_completion": "2027-06", "completion": "2031-12", "enrollment": 5000, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT01960972", "title": "Launching a Salt Substitute to Reduce Blood Pressure at the Population Level in Peru", "status": "COMPLETED", "last_update": "2021-08-26", "results_first": null, "primary_completion": "2017-03", "completion": "2017-04", "enrollment": 2376, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT02105727", "title": "Changing Population Salt Consumption in Lithgow, Australia", "status": "COMPLETED", "last_update": "2014-11-18", "results_first": null, "primary_completion": "2014-04", "completion": "2014-04", "enrollment": 991, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT02439749", "title": "SPYRAL PIVOTAL - SPYRAL HTN-OFF MED Study", "status": "COMPLETED", "last_update": "2025-03-28", "results_first": "2021-05-27", "primary_completion": "2020-04-30", "completion": "2023-10-25", "enrollment": 366, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT02439775", "title": "SPYRAL HTN-ON MED Study of Renal Denervation With the Symplicity Spyral™ Multi-electrode Renal Denervation System", "status": "COMPLETED", "last_update": "2026-07-30", "results_first": "2023-09-15", "primary_completion": "2022-08-18", "completion": "2025-08-14", "enrollment": 337, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT02603809", "title": "Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential Hypertension", "status": "COMPLETED", "last_update": "2022-11-23", "results_first": "2020-04-13", "primary_completion": "2017-02-28", "completion": "2017-04-07", "enrollment": 1659, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT03398785", "title": "Adrenal Artery Ablation Treats Primary Aldosteronism", "status": "COMPLETED", "last_update": "2019-07-08", "results_first": null, "primary_completion": "2018-12-31", "completion": "2019-06-30", "enrollment": 66, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT03453268", "title": "Impact of Reducing Antihypertensive Treatment on Mortality in Frail Subjects With Low Systolic Blood Pressure (SBP).", "status": "COMPLETED", "last_update": "2025-07-20", "results_first": null, "primary_completion": "2024-08-15", "completion": "2024-08-15", "enrollment": 1048, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT03541174", "title": "A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety", "status": "COMPLETED", "last_update": "2023-03-21", "results_first": "2023-03-21", "primary_completion": "2021-05-14", "completion": "2022-04-25", "enrollment": 730, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT03909659", "title": "The Effects on Blood Pressure of Salt Substitute Among Adults With Hypertension in India", "status": "COMPLETED", "last_update": "2021-04-01", "results_first": null, "primary_completion": "2020-05-30", "completion": "2020-11-30", "enrollment": 502, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT03934307", "title": "A Study to Evaluate ALN-AGT01 in Patients With Hypertension", "status": "COMPLETED", "last_update": "2023-01-17", "results_first": null, "primary_completion": "2022-04-20", "completion": "2023-01-04", "enrollment": 124, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT04060641", "title": "Association Between a Multi-Gene Panel and Renal Denervation Effectiveness in Patients With Hypertension", "status": "UNKNOWN", "last_update": "2022-02-16", "results_first": null, "primary_completion": "2022-05-01", "completion": "2022-09-30", "enrollment": 30, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT04162366", "title": "A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease.", "status": "WITHDRAWN", "last_update": "2022-11-23", "results_first": null, "primary_completion": "2021-06-30", "completion": "2021-07-15", "enrollment": 0, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT04519658", "title": "A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)", "status": "COMPLETED", "last_update": "2023-07-24", "results_first": "2023-06-28", "primary_completion": "2022-06-14", "completion": "2022-06-14", "enrollment": 275, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT04797403", "title": "Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-10-01", "results_first": null, "primary_completion": "2026-10", "completion": "2026-10", "enrollment": 1306, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT04936035", "title": "A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension", "status": "COMPLETED", "last_update": "2025-12-23", "results_first": "2024-12-27", "primary_completion": "2023-04-04", "completion": "2024-12-05", "enrollment": 394, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT05031819", "title": "Managing Hypertension Among People Living With HIV", "status": "COMPLETED", "last_update": "2025-11-21", "results_first": null, "primary_completion": "2025-04-30", "completion": "2025-10-31", "enrollment": 960, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05047731", "title": "Antihypertensive Deprescribing in Long-term Care", "status": "COMPLETED", "last_update": "2026-01-08", "results_first": null, "primary_completion": "2025-11-30", "completion": "2025-11-30", "enrollment": 522, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05103332", "title": "Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)", "status": "COMPLETED", "last_update": "2025-11-03", "results_first": "2025-07-09", "primary_completion": "2023-12-11", "completion": "2024-09-13", "enrollment": 663, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT05405920", "title": "Caribbean and South America Team-based Strategy to Control Hypertension", "status": "COMPLETED", "last_update": "2026-10-01", "results_first": null, "primary_completion": "2026-09-09", "completion": "2026-09-09", "enrollment": 1706, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05414526", "title": "Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)", "status": "COMPLETED", "last_update": "2026-05-12", "results_first": null, "primary_completion": "2025-09-10", "completion": "2025-09-10", "enrollment": 4655, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05425030", "title": "A Community Health Worker-Led LSSS Intervention in Bangladesh", "status": "COMPLETED", "last_update": "2026-02-17", "results_first": null, "primary_completion": "2024-05-30", "completion": "2024-12-01", "enrollment": 618, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05658705", "title": "Preoperative Supine Time for Adrenal Venous Sampling", "status": "UNKNOWN", "last_update": "2024-04-26", "results_first": null, "primary_completion": "2025-03-29", "completion": "2025-03-29", "enrollment": 120, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT05732727", "title": "Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease", "status": "RECRUITING", "last_update": "2026-08-03", "results_first": null, "primary_completion": "2029-03", "completion": "2029-03", "enrollment": 720, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT05769608", "title": "A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen", "status": "COMPLETED", "last_update": "2026-01-20", "results_first": null, "primary_completion": "2025-01-15", "completion": "2025-01-15", "enrollment": 285, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05846503", "title": "iHEART-SA Intervention Study", "status": "COMPLETED", "last_update": "2025-12-10", "results_first": null, "primary_completion": "2025-05-31", "completion": "2025-08-31", "enrollment": 4378, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT05968430", "title": "Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-09-29", "results_first": null, "primary_completion": "2025-12-30", "completion": "2027-05", "enrollment": 1076, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT06108427", "title": "REnin-guided TherApy With MinEralocorticoid Receptor Antagonists in Primary Aldosteronism - Feasibility Study", "status": "RECRUITING", "last_update": "2026-03-17", "results_first": null, "primary_completion": "2027-09", "completion": "2027-09", "enrollment": 58, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT06150924", "title": "Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria", "status": "COMPLETED", "last_update": "2026-06-03", "results_first": "2026-06-03", "primary_completion": "2025-02-27", "completion": "2025-04-23", "enrollment": 60, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT06153693", "title": "Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension", "status": "COMPLETED", "last_update": "2026-05-01", "results_first": null, "primary_completion": "2024-12-10", "completion": "2025-01-24", "enrollment": 1083, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT06168409", "title": "A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension", "status": "COMPLETED", "last_update": "2026-08-06", "results_first": "2026-08-06", "primary_completion": "2025-08-17", "completion": "2025-08-17", "enrollment": 218, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT06268873", "title": "A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-06-26", "results_first": null, "primary_completion": "2028-02-24", "completion": "2028-02-24", "enrollment": 2554, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT06272487", "title": "Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)", "status": "COMPLETED", "last_update": "2026-03-02", "results_first": null, "primary_completion": "2025-06-19", "completion": "2025-12-01", "enrollment": 375, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT06336356", "title": "A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension", "status": "COMPLETED", "last_update": "2025-12-17", "results_first": "2025-12-17", "primary_completion": "2024-12-04", "completion": "2024-12-04", "enrollment": 48, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT06423352", "title": "A Study to Evaluate Zilebesiran in Japanese Patients With Mild to Moderate Hypertension", "status": "COMPLETED", "last_update": "2026-04-30", "results_first": "2026-04-30", "primary_completion": "2025-07-17", "completion": "2025-07-17", "enrollment": 36, "enrollment_type": "ACTUAL", "has_results": true }, { "nct": "NCT06578975", "title": "HT-ENDO: A Multiomics-based Biomarker for the Diagnosis of Endocrine Hypertension: a Pragmatic, Diagnostic, Randomized, Outcome-based Trial", "status": "UNKNOWN", "last_update": "2024-08-30", "results_first": null, "primary_completion": "2026-01-01", "completion": "2026-01-01", "enrollment": 250, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT06742723", "title": "A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure", "status": "RECRUITING", "last_update": "2026-09-25", "results_first": null, "primary_completion": "2029-12-18", "completion": "2029-12-18", "enrollment": 5000, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT06785454", "title": "A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension", "status": "COMPLETED", "last_update": "2026-08-21", "results_first": null, "primary_completion": "2025-12-17", "completion": "2025-12-29", "enrollment": 48, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT06877221", "title": "Safety and Efficacy of Modulated Ultrasound Renal Denervation for HTN", "status": "RECRUITING", "last_update": "2025-06-19", "results_first": null, "primary_completion": "2027-12", "completion": "2030-12", "enrollment": 204, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT06907147", "title": "SPYRAL GEMINI Pilot Study", "status": "RECRUITING", "last_update": "2026-06-24", "results_first": null, "primary_completion": "2029-12-22", "completion": "2029-12-22", "enrollment": 175, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT06959134", "title": "Community Health Workers-led Multicomponent Intervention for Hypertension Control in Rwanda", "status": "COMPLETED", "last_update": "2025-05-06", "results_first": null, "primary_completion": "2025-01-10", "completion": "2025-01-30", "enrollment": 200, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT07013929", "title": "Spyral InSight Study", "status": "RECRUITING", "last_update": "2026-05-04", "results_first": null, "primary_completion": "2027-02-28", "completion": "2027-07-01", "enrollment": 19, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07027254", "title": "PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism", "status": "RECRUITING", "last_update": "2025-06-18", "results_first": null, "primary_completion": "2027-06-01", "completion": "2027-12-01", "enrollment": 90, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07051811", "title": "To Evaluate the Safety and Efficacy of a Single-Use IVUS Ablation for Primary Hypertension", "status": "RECRUITING", "last_update": "2025-07-04", "results_first": null, "primary_completion": "2027-12-31", "completion": "2029-12-31", "enrollment": 213, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07081243", "title": "Symplicity China Study", "status": "RECRUITING", "last_update": "2025-11-17", "results_first": null, "primary_completion": "2028-06-30", "completion": "2031-12-30", "enrollment": 500, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07114757", "title": "REnal Denervation After Stroke (REDs) Study - A Randomized Clinical Trial of Renal Denervation in the Subacute Phase of Stroke", "status": "NOT_YET_RECRUITING", "last_update": "2025-08-11", "results_first": null, "primary_completion": "2027-09-25", "completion": "2029-09-25", "enrollment": 108, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07174622", "title": "Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation", "status": "RECRUITING", "last_update": "2026-04-22", "results_first": null, "primary_completion": "2029-06", "completion": "2029-06", "enrollment": 1000, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07178964", "title": "POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS", "status": "NOT_YET_RECRUITING", "last_update": "2025-09-17", "results_first": null, "primary_completion": "2026-06-30", "completion": "2026-09-30", "enrollment": 80, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07181109", "title": "Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease", "status": "RECRUITING", "last_update": "2026-10-15", "results_first": null, "primary_completion": "2030-09-23", "completion": "2030-09-23", "enrollment": 11000, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07222917", "title": "A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-09-01", "results_first": null, "primary_completion": "2026-12-10", "completion": "2026-12-10", "enrollment": 222, "enrollment_type": "ACTUAL", "has_results": false }, { "nct": "NCT07228065", "title": "Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control", "status": "ENROLLING_BY_INVITATION", "last_update": "2026-08-11", "results_first": null, "primary_completion": "2027-04-30", "completion": "2027-06-30", "enrollment": 720, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07328230", "title": "Superselective Adrenal Arterial Embolization Versus Oral Spironolactone for Treatment of Idiopathic Hyperaldosteronism", "status": "RECRUITING", "last_update": "2026-01-09", "results_first": null, "primary_completion": "2025-12-31", "completion": "2025-12-31", "enrollment": 172, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07336433", "title": "SMART-IC-Pilot Study", "status": "NOT_YET_RECRUITING", "last_update": "2026-01-13", "results_first": null, "primary_completion": "2027-06-30", "completion": "2027-12-31", "enrollment": 15, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07460882", "title": "The Impact of Low Sodium Salt Substitute Use on Serum Potassium Levels Among Patients With Hypertension", "status": "RECRUITING", "last_update": "2026-08-21", "results_first": null, "primary_completion": "2027-03-31", "completion": "2027-09-30", "enrollment": 607, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07553442", "title": "A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran", "status": "RECRUITING", "last_update": "2026-10-08", "results_first": null, "primary_completion": "2028-04-01", "completion": "2028-10-01", "enrollment": 93, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07635914", "title": "A Study Evaluating Aprocitentan Tablets(SYH9108) for the Treatment of Resistant Hypertension", "status": "NOT_YET_RECRUITING", "last_update": "2026-06-09", "results_first": null, "primary_completion": "2029-12-28", "completion": "2030-05-31", "enrollment": 382, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07664787", "title": "Safety and Efficacy of Renal Denervation for Untreated Grade I Hypertension: a Pilot Study", "status": "NOT_YET_RECRUITING", "last_update": "2026-06-24", "results_first": null, "primary_completion": "2027-12-30", "completion": "2027-12-30", "enrollment": 20, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07679828", "title": "Polypills Approach for Multiple Cardiovascular Risk Factors", "status": "RECRUITING", "last_update": "2026-09-16", "results_first": null, "primary_completion": "2029-12-31", "completion": "2030-03-01", "enrollment": 8252, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07686120", "title": "A Phase IIIb Study to Investigate the Effect of Baxdrostat in Chinese Participants With Uncontrolled Hypertension.", "status": "RECRUITING", "last_update": "2026-10-15", "results_first": null, "primary_completion": "2028-02-09", "completion": "2028-02-09", "enrollment": 286, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07687160", "title": "SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-14", "results_first": null, "primary_completion": "2028-08", "completion": "2028-12", "enrollment": 30, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07688928", "title": "Efficacy and Safety of Finerenone Compared to Spironolactone in Treatment of Primary Aldosteronism", "status": "RECRUITING", "last_update": "2026-07-07", "results_first": null, "primary_completion": "2027-03", "completion": "2027-09", "enrollment": 104, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07727252", "title": "Early Aldo Blockade in Subclinical PA", "status": "NOT_YET_RECRUITING", "last_update": "2026-07-27", "results_first": null, "primary_completion": "2029-08-01", "completion": "2029-08-01", "enrollment": 880, "enrollment_type": "ESTIMATED", "has_results": false }, { "nct": "NCT07746271", "title": "Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial", "status": "NOT_YET_RECRUITING", "last_update": "2026-09-18", "results_first": null, "primary_completion": "2029-12-31", "completion": "2030-04-30", "enrollment": 4120, "enrollment_type": "ESTIMATED", "has_results": false } ], "changes_since_2026_10_12": { "NCT07686120": "NOT_YET_RECRUITING -> RECRUITING (last update 2026-10-15)", "NCT07687160": "primary completion 2028-02 -> 2028-08; completion 2028-02 -> 2028-12; still NOT_YET_RECRUITING", "NCT07181109": "last-update date only (2026-09-18 -> 2026-10-15); status, enrolment and dates unchanged" }, "results_first_posted_in_window": [], "query_term_searches": { "CONSEP primary aldosteronism": 0, "primary aldosteronism screening decision support": [ "NCT05925569" ], "enalapril hydrochlorothiazide nifedipine postpartum": 0, "DANTON antihypertensive": 0 }, "added": [ "NCT05925569 (ALERT-PA): randomised, actual n=12,501, primary completion 2024-12-09, ACTIVE_NOT_RECRUITING, hasResults false" ] }, "guidelines_and_statistics_pages_checked": { "NICE NG136": "Published 28 August 2019, last updated 26 February 2026; unchanged.", "WHO fact sheet": "dateModified 2025-09-25; 1.4 billion adults aged 30-79 in 2024; unchanged; no PMID.", "PubMed guideline[pt] AND hypertension[majr], dp 2026/10/01-2026/10/19": "1 record, 42554264 (ISH Africa, already cited).", "Europe PMC ISH Africa / ACC pathway": "Both still not open access; full-text follow-ups not completable." }, "triage": { "wiki_edits": [ "42861682", "42885806", "42886602", "42888381", "42865623", "42864372", "42866865", "42887271", "42872422", "42888852", "42872749", "42869921" ], "open_questions_only": [ "42861788" ], "bibliography_only": [ "42885348", "42882155", "42885485", "42886511" ], "considered_not_added": { "42877905": "Patchen remote prenatal BP monitoring; retrospective, Crossref DOI 404", "42892130": "PREVENT-PE qualitative", "42864373": "angiotensin peptide signatures, n=72 completers", "42889948,42876404": "renal denervation case series n=11 and n=18, uncontrolled", "42886197,42886198": "Am Fam Physician summaries of guidelines already registered", "41645899": "Owei 2026 review of PA screening guidance (outside window; full text not read)", "42861937,42888192": "commentary/letters" } } }