{ "condition": "hypertension", "date": "2026-10-12", "engine": "Grok", "window": { "mindate": "2026/09/01", "maxdate": "2026/10/12", "default_datetype": "edat" }, "window_decision": "Entrez date (edat) 2026/09/01 to 2026/10/12, because the last content pass was the 2026-09-01 audit. One high-signal query was also run on publication date (pdat) over the same bounds.", "sources_queried": [ "PubMed E-utilities esearch/esummary/efetch (tool=lifebank, no email, no API key)", "Europe PMC REST search, resultType lite", "ClinicalTrials.gov API v2: all 61 previously cited NCT records, plus full study fetches for NCT05414526 and NCT05732727, plus query.term searches", "Crossref works (no mailto) for DOI resolution and updated-by retraction checks on records intended for citation", "NICE NG136 HTML page", "WHO hypertension fact sheet HTML page" ], "sources_probed_not_searched_as_databases": { "cochranelibrary.com": "HTTP 403 this session. CDSR was searched via PubMed. CENTRAL was not searched. Do not read an absence here as a CENTRAL absence.", "scielo": "HTTP 403 this session.", "lilacs": "Homepage returned HTTP 200. A search was not completed (pesquisa.bvsalud.org failed to open; a lilacs search URL returned 404). Not an HTTP 403. Not searched.", "who_ictrp": "Homepage HTTP 200. The search interface is JavaScript-driven and was not queried. Not counted as searched.", "anzctr": "Not queried. CONSEP has no ClinicalTrials.gov hit; an Australian registry identifier was not established.", "ctri": "Not queried. The Bhagat postpartum trial had no ClinicalTrials.gov hit.", "euctr_ctis": "Not confirmed for THINK (NCT05732727).", "embase_scopus_wos": "Not available.", "unpaywall": "Skipped. LIFEBANK_CONTACT_EMAIL was unset. No owner address was sent." }, "pubmed": { "broad_majr_edat": { "datetype": "edat", "query": "(hypertension[majr]) AND 2026/09/01:2026/10/12[edat]", "topic_term": "hypertension[majr]", "count": 297, "translation": "\"hypertension\"[MeSH Major Topic] AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42834212", "42734462", "42710597", "42853626", "42826222", "42806698", "42802577", "42771697", "42720262", "42703876", "42691155", "42683512", "42841345", "42822005", "42800139", "42775845", "42754840", "42743594", "42682213", "42678121" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "broad_ti_edat": { "datetype": "edat", "query": "(hypertension[ti]) AND 2026/09/01:2026/10/12[edat]", "topic_term": "hypertension[ti]", "count": 827, "translation": "\"hypertension\"[Title] AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42834212", "42710597", "42853626", "42826222", "42815904", "42802577", "42771697", "42720262", "42691155", "42683512", "42678395", "42761503", "42841021", "42840412", "42831157", "42830762", "42827889", "42827825", "42824628", "42822005" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "high_signal_edat": { "datetype": "edat", "query": "((hypertension[majr] OR \"blood pressure\"[majr]) AND (practice guideline[pt] OR guideline[pt] OR meta-analysis[pt] OR \"systematic review\"[pt] OR \"randomized controlled trial\"[pt])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[majr] OR \"blood pressure\"[majr]) AND (practice guideline[pt] OR guideline[pt] OR meta-analysis[pt] OR \"systematic review\"[pt] OR \"randomized controlled trial\"[pt])", "count": 28, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"blood pressure\"[MeSH Major Topic]) AND (\"practice guideline\"[Publication Type] OR \"guideline\"[Publication Type] OR \"meta-analysis\"[Publication Type] OR \"systematic review\"[Publication Type] OR \"randomized controlled trial\"[Publication Type]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42678121", "42848972", "42831437", "42777740", "42853857", "42808437", "42851099", "42836438", "42809028", "42801345", "42788405", "42779403", "42765929", "42760729", "42747486", "42812167", "42794458", "42796927", "42715468", "42693416", "42757615", "42754828", "42740560", "42723352", "42740758", "42763299", "42732603", "42732602" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "high_signal_dp": { "datetype": "pdat", "query": "((hypertension[majr] OR \"blood pressure\"[majr]) AND (practice guideline[pt] OR guideline[pt] OR meta-analysis[pt] OR \"systematic review\"[pt] OR \"randomized controlled trial\"[pt])) AND 2026/09/01:2026/10/12[pdat]", "topic_term": "(hypertension[majr] OR \"blood pressure\"[majr]) AND (practice guideline[pt] OR guideline[pt] OR meta-analysis[pt] OR \"systematic review\"[pt] OR \"randomized controlled trial\"[pt])", "count": 105, "translation": "(\"hypertension\"[MeSH Major Topic] OR \"blood pressure\"[MeSH Major Topic]) AND (\"practice guideline\"[Publication Type] OR \"guideline\"[Publication Type] OR \"meta-analysis\"[Publication Type] OR \"systematic review\"[Publication Type] OR \"randomized controlled trial\"[Publication Type]) AND 2026/09/01:2026/10/12[Date - Publication]", "pmids_returned": [ "42678121", "42848972", "42777740", "42853857", "42808437", "42669885", "42667900", "42851099", "42836438", "42668015", "42606691", "42605672", "42586107", "42554270", "42554266", "42554265", "42554264", "42547561", "42545101", "42542446", "42520885", "42517337", "42488976", "42474349", "42468834", "42454434", "42426169", "42407048", "42398262", "42338082", "42314756", "42314542", "42303150", "42259717", "42249245", "42248770", "42241294", "42230185", "42220219", "42126470", "42056360", "42025692", "42013991", "41933609", "41533725", "41361156", "40660030", "42809028", "42801345", "42788405", "42779403", "42765929", "42760729", "42747486", "42812167", "42628181", "42566870", "42176901", "42794458", "42796927", "42585603", "42715468", "42693416", "41973953", "42757615", "42754828", "42740560", "42723352", "42622217", "42595776", "42586098", "42585721", "42578528", "42526228", "42495732", "42492370", "42489850", "42488947", "42484370", "42474350", "42462335", "42458015", "42436627", "42396775", "42380667", "42373836", "42371360", "42359837", "42345116", "42319207", "42302394", "42299849", "42277996", "42244376", "42201301", "42191019", "42117700", "42091237", "42082844", "42031586", "42031190", "41996612", "41820738", "41771369", "41275512" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "cochrane_htn": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab] OR antihypertensive[tiab])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab] OR antihypertensive[tiab])", "count": 3, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR \"blood pressure\"[Title/Abstract] OR \"antihypertensive\"[Title/Abstract]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42788405", "42757634", "42742033" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "cochrane_measurement": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab]) AND (ambulatory OR \"home blood\" OR \"white coat\" OR masked OR cuffless OR measurement OR monitor*)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab]) AND (ambulatory OR \"home blood\" OR \"white coat\" OR masked OR cuffless OR measurement OR monitor*)", "count": 1, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR \"blood pressure\"[Title/Abstract]) AND (\"ambulatories\"[All Fields] OR \"ambulatory\"[All Fields] OR \"home blood\"[All Fields] OR \"white coat\"[All Fields] OR (\"mask s\"[All Fields] OR \"masked\"[All Fields] OR \"masking\"[All Fields] OR \"masks\"[MeSH Terms] OR \"masks\"[All Fields]) OR \"cuffless\"[All Fields] OR (\"measurability\"[All Fields] OR \"measurable\"[All Fields] OR \"measurably\"[All Fields] OR \"measure s\"[All Fields] OR \"measureable\"[All Fields] OR \"measured\"[All Fields] OR \"measurement\"[All Fields] OR \"measurement s\"[All Fields] OR \"measurements\"[All Fields] OR \"measurer\"[All Fields] OR \"measurers\"[All Fields] OR \"measuring\"[All Fields] OR \"measurings\"[All Fields] OR \"measurment\"[All Fields] OR \"measurments\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"measure\"[All Fields] OR \"measures\"[All Fields]) OR \"monitor*\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42742033" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "cochrane_targets": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab]) AND (target* OR intensive OR SPRINT OR threshold)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab]) AND (target* OR intensive OR SPRINT OR threshold)", "count": 1, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR \"blood pressure\"[Title/Abstract]) AND (\"target*\"[All Fields] OR (\"intensive\"[All Fields] OR \"intensives\"[All Fields]) OR (\"sprint\"[All Fields] OR \"sprinted\"[All Fields] OR \"sprinting\"[All Fields] OR \"sprints\"[All Fields]) OR (\"threshold\"[All Fields] OR \"thresholds\"[All Fields])) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42788405" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "cochrane_drugs": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR antihypertensive[tiab]) AND (drug OR pharmacolog* OR spironolactone OR \"calcium channel\" OR ACE OR angiotensin OR diuretic OR \"beta blocker\" OR \"beta-blocker\")) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR antihypertensive[tiab]) AND (drug OR pharmacolog* OR spironolactone OR \"calcium channel\" OR ACE OR angiotensin OR diuretic OR \"beta blocker\" OR \"beta-blocker\")", "count": 1, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR \"antihypertensive\"[Title/Abstract]) AND (\"drug\"[All Fields] OR \"pharmacolog*\"[All Fields] OR (\"spironolacton\"[All Fields] OR \"spironolactone\"[Supplementary Concept] OR \"spironolactone\"[All Fields] OR \"spironolactone\"[MeSH Terms] OR \"spironolactone s\"[All Fields] OR \"spironolactones\"[All Fields]) OR \"calcium channel\"[All Fields] OR (\"avian conserv ecol\"[Journal] OR \"ann clin epidemiol\"[Journal] OR \"ann cancer epidemiol\"[Journal] OR \"ace\"[All Fields]) OR (\"angiotensin s\"[All Fields] OR \"angiotensine\"[All Fields] OR \"angiotensins\"[Supplementary Concept] OR \"angiotensins\"[All Fields] OR \"angiotensin\"[All Fields] OR \"angiotensins\"[MeSH Terms]) OR (\"diuretics\"[Pharmacological Action] OR \"diuretics\"[Supplementary Concept] OR \"diuretics\"[All Fields] OR \"diuretic\"[All Fields] OR \"diuretics\"[MeSH Terms]) OR \"beta-blocker\"[All Fields] OR \"beta-blocker\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42788405" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "cochrane_lifestyle": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab]) AND (sodium OR salt OR potassium OR exercise OR weight OR alcohol OR diet OR DASH)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR \"blood pressure\"[tiab]) AND (sodium OR salt OR potassium OR exercise OR weight OR alcohol OR diet OR DASH)", "count": 2, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR \"blood pressure\"[Title/Abstract]) AND (\"sodium\"[Supplementary Concept] OR \"sodium\"[All Fields] OR \"sodium\"[MeSH Terms] OR \"sodiums\"[All Fields] OR (\"sodium chloride\"[Supplementary Concept] OR \"sodium chloride\"[All Fields] OR \"salt\"[All Fields] OR \"sodium chloride\"[MeSH Terms] OR (\"sodium\"[All Fields] AND \"chloride\"[All Fields])) OR (\"potassium dietary\"[Supplementary Concept] OR \"potassium dietary\"[All Fields] OR \"potassium\"[All Fields] OR \"potassium\"[Supplementary Concept] OR \"potassium, dietary\"[MeSH Terms] OR (\"potassium\"[All Fields] AND \"dietary\"[All Fields]) OR \"dietary potassium\"[All Fields] OR \"potassium\"[MeSH Terms]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"weight s\"[All Fields] OR \"weighted\"[All Fields] OR \"weighting\"[All Fields] OR \"weightings\"[All Fields] OR \"weights and measures\"[MeSH Terms] OR (\"weights\"[All Fields] AND \"measures\"[All Fields]) OR \"weights and measures\"[All Fields] OR \"weight\"[All Fields] OR \"body weight\"[MeSH Terms] OR (\"body\"[All Fields] AND \"weight\"[All Fields]) OR \"body weight\"[All Fields] OR \"weights\"[All Fields]) OR (\"alcohol s\"[All Fields] OR \"alcoholate\"[All Fields] OR \"alcoholates\"[All Fields] OR \"alcohols\"[Supplementary Concept] OR \"alcohols\"[All Fields] OR \"alcohols\"[MeSH Terms] OR \"ethanol\"[Supplementary Concept] OR \"ethanol\"[All Fields] OR \"alcohol\"[All Fields] OR \"ethanol\"[MeSH Terms]) OR (\"diet\"[MeSH Terms] OR \"diet\"[All Fields]) OR \"DASH\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42757634", "42742033" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "cochrane_devices": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (\"renal denervation\" OR \"resistant hypertension\" OR baroreflex)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (\"renal denervation\" OR \"resistant hypertension\" OR baroreflex)", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"renal denervation\"[All Fields] OR \"resistant hypertension\"[All Fields] OR (\"baroreflex\"[MeSH Terms] OR \"baroreflex\"[All Fields] OR \"baroreflexes\"[All Fields] OR \"baroreflexive\"[All Fields])) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [], "outputmessages": [ "No items found." ] }, "error": null }, "cochrane_pregnancy": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR preeclampsia OR pre-eclampsia) AND (pregnan* OR postpartum OR antenatal)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR preeclampsia OR pre-eclampsia) AND (pregnan* OR postpartum OR antenatal)", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR (\"pre eclampsia\"[MeSH Terms] OR \"pre eclampsia\"[All Fields] OR \"preeclampsia\"[All Fields]) OR (\"pre eclampsia\"[MeSH Terms] OR \"pre eclampsia\"[All Fields] OR (\"pre\"[All Fields] AND \"eclampsia\"[All Fields]) OR \"pre eclampsia\"[All Fields])) AND (\"pregnan*\"[All Fields] OR (\"postpartum period\"[MeSH Terms] OR (\"postpartum\"[All Fields] AND \"period\"[All Fields]) OR \"postpartum period\"[All Fields] OR \"postpartum\"[All Fields]) OR (\"antenatal\"[All Fields] OR \"antenatally\"[All Fields])) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [], "outputmessages": [ "No items found." ] }, "error": null }, "cochrane_secondary": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (\"primary aldosteronism\" OR hyperaldosteronism OR \"secondary hypertension\" OR renovascular)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (\"primary aldosteronism\" OR hyperaldosteronism OR \"secondary hypertension\" OR renovascular)", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"primary aldosteronism\"[All Fields] OR (\"hyperaldosteronism\"[MeSH Terms] OR \"hyperaldosteronism\"[All Fields] OR \"hyperaldosteronisms\"[All Fields]) OR \"secondary hypertension\"[All Fields] OR \"renovascular\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [], "outputmessages": [ "No items found." ] }, "error": null }, "cochrane_implementation": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND hypertension[tiab] AND (adherence OR implementation OR \"community health\" OR polypill OR \"task shifting\")) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND hypertension[tiab] AND (adherence OR implementation OR \"community health\" OR polypill OR \"task shifting\")", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND \"hypertension\"[Title/Abstract] AND (\"adherance\"[All Fields] OR \"adhere\"[All Fields] OR \"adhered\"[All Fields] OR \"adherence\"[All Fields] OR \"adherences\"[All Fields] OR \"adherent\"[All Fields] OR \"adherents\"[All Fields] OR \"adherer\"[All Fields] OR \"adherers\"[All Fields] OR \"adheres\"[All Fields] OR \"adhering\"[All Fields] OR (\"implementability\"[All Fields] OR \"implementable\"[All Fields] OR \"implementation\"[All Fields] OR \"implementation s\"[All Fields] OR \"implementational\"[All Fields] OR \"implementations\"[All Fields] OR \"implementer\"[All Fields] OR \"implementers\"[All Fields] OR \"implemention\"[All Fields]) OR \"community health\"[All Fields] OR (\"polypill\"[All Fields] OR \"polypills\"[All Fields]) OR \"task shifting\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [], "outputmessages": [ "No items found." ] }, "error": null }, "cochrane_frail": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR antihypertensive[tiab]) AND (frail* OR elderly OR \"older adult*\" OR deprescrib*)) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (hypertension[tiab] OR antihypertensive[tiab]) AND (frail* OR elderly OR \"older adult*\" OR deprescrib*)", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertension\"[Title/Abstract] OR \"antihypertensive\"[Title/Abstract]) AND (\"frail*\"[All Fields] OR (\"aged\"[MeSH Terms] OR \"aged\"[All Fields] OR \"elderly\"[All Fields] OR \"elderlies\"[All Fields] OR \"elderly s\"[All Fields] OR \"elderlys\"[All Fields]) OR \"older adult*\"[All Fields] OR \"deprescrib*\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [], "outputmessages": [ "No items found." ] }, "error": null }, "cochrane_emergency": { "datetype": "edat", "query": "(\"Cochrane Database Syst Rev\"[jour] AND (\"hypertensive emergenc*\" OR \"hypertensive crisis\" OR \"malignant hypertension\")) AND 2026/09/01:2026/10/12[edat]", "topic_term": "\"Cochrane Database Syst Rev\"[jour] AND (\"hypertensive emergenc*\" OR \"hypertensive crisis\" OR \"malignant hypertension\")", "count": 0, "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"hypertensive emergenc*\"[All Fields] OR \"hypertensive crisis\"[All Fields] OR \"malignant hypertension\"[All Fields]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [], "outputmessages": [ "No items found." ] }, "error": null }, "measurement": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (ambulatory[ti] OR \"home blood\"[ti] OR \"white-coat\"[ti] OR \"white coat\"[ti] OR masked[ti] OR cuffless[ti] OR oscillometric[ti] OR \"blood pressure measurement\"[ti] OR validation[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti]) AND (ambulatory[ti] OR \"home blood\"[ti] OR \"white-coat\"[ti] OR \"white coat\"[ti] OR masked[ti] OR cuffless[ti] OR oscillometric[ti] OR \"blood pressure measurement\"[ti] OR validation[ti])", "count": 64, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND (\"ambulatory\"[Title] OR \"home blood\"[Title] OR \"white-coat\"[Title] OR \"white-coat\"[Title] OR \"masked\"[Title] OR \"cuffless\"[Title] OR \"oscillometric\"[Title] OR \"blood pressure measurement\"[Title] OR \"validation\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42800139", "42775845", "42830468", "42855111", "42853222", "42848570", "42847650", "42838984", "42836334", "42834072", "42833254", "42820455", "42827114", "42849428", "42847119", "42847102", "42846709", "42687043", "42820409", "42810253", "42802228", "42813640", "42789602", "42782336", "42775664", "42772752", "42771630", "42768439", "42760648", "42758898", "42758442", "42753491", "42750636", "42764982", "42744930", "42795885", "42730378", "42728325", "42725447", "42794495", "42722734", "42722732", "42750633", "42716956", "42711498", "42700743", "42761081", "42755914", "42703370", "42860303", "42772987", "42740183", "42728063", "42723367", "42699225", "42680597", "42675704", "42739184", "42753339", "42695370", "42730166", "42691834", "42689301", "42682142" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "epidemiology": { "datetype": "edat", "query": "(hypertension[ti] AND (prevalence[ti] OR incidence[ti] OR \"global burden\"[tiab] OR \"blood pressure control\"[ti] OR cascade[ti] OR NHANES[ti] OR \"NCD Risk Factor\"[tiab])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "hypertension[ti] AND (prevalence[ti] OR incidence[ti] OR \"global burden\"[tiab] OR \"blood pressure control\"[ti] OR cascade[ti] OR NHANES[ti] OR \"NCD Risk Factor\"[tiab])", "count": 50, "translation": "\"hypertension\"[Title] AND (\"prevalence\"[Title] OR \"incidence\"[Title] OR \"global burden\"[Title/Abstract] OR \"blood pressure control\"[Title] OR \"cascade\"[Title] OR \"NHANES\"[Title] OR \"NCD Risk Factor\"[Title/Abstract]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42827825", "42701880", "42858041", "42844677", "42851590", "42845032", "42834823", "42828506", "42827113", "42825323", "42847220", "42822535", "42821184", "42696853", "42856673", "42824443", "42824372", "42811294", "42809241", "42809875", "42825274", "42772430", "42766099", "42759120", "42749213", "42744930", "42746613", "42756978", "42726776", "42726727", "42720983", "42769995", "42707626", "42704541", "42760941", "42712874", "42697181", "42756296", "42693416", "42686811", "42847082", "42813480", "42780603", "42703909", "42699213", "42688995", "42688712", "42699578", "42787824", "42769838" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "pathophysiology": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (aldosterone[ti] OR \"pressure natriuresis\"[tiab] OR sympathetic[ti] OR \"arterial stiffness\"[ti] OR microbiome[ti] OR \"immune\"[ti] AND hypertension[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti]) AND (aldosterone[ti] OR \"pressure natriuresis\"[tiab] OR sympathetic[ti] OR \"arterial stiffness\"[ti] OR microbiome[ti] OR \"immune\"[ti] AND hypertension[ti])", "count": 34, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND ((\"aldosterone\"[Title] OR \"pressure natriuresis\"[Title/Abstract] OR \"sympathetic\"[Title] OR \"arterial stiffness\"[Title] OR \"microbiome\"[Title] OR \"immune\"[Title]) AND \"hypertension\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42802577", "42687395", "42858016", "42850365", "42827416", "42827115", "42851099", "42847229", "42847228", "42847227", "42847226", "42847224", "42847220", "42781105", "42775476", "42809094", "42800599", "42818059", "42778148", "42793041", "42777113", "42754669", "42730398", "42794478", "42795360", "42710144", "42783763", "42757615", "42680927", "42695495", "42795283", "42712928", "42781345", "42706751" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "genetics": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (GWAS[tiab] OR polygenic[ti] OR monogenic[ti] OR Liddle[ti] OR pharmacogenom*[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti]) AND (GWAS[tiab] OR polygenic[ti] OR monogenic[ti] OR Liddle[ti] OR pharmacogenom*[ti])", "count": 8, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND (\"GWAS\"[Title/Abstract] OR \"polygenic\"[Title] OR \"monogenic\"[Title] OR \"Liddle\"[Title] OR \"pharmacogenom*\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42858016", "42756691", "42779510", "42827937", "42797533", "42812492", "42695459", "42687977" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "secondary_pa": { "datetype": "edat", "query": "((\"primary aldosteronism\"[ti] OR \"primary hyperaldosteronism\"[ti] OR \"aldosteronism\"[ti] OR \"renovascular hypertension\"[ti] OR \"secondary hypertension\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(\"primary aldosteronism\"[ti] OR \"primary hyperaldosteronism\"[ti] OR \"aldosteronism\"[ti] OR \"renovascular hypertension\"[ti] OR \"secondary hypertension\"[ti])", "count": 54, "translation": "(\"primary aldosteronism\"[Title] OR \"primary hyperaldosteronism\"[Title] OR \"aldosteronism\"[Title] OR \"renovascular hypertension\"[Title] OR \"secondary hypertension\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42745063", "42855774", "42855766", "42850208", "42844194", "42836924", "42786607", "42833710", "42847227", "42741517", "42724476", "42814396", "42805595", "42789196", "42851797", "42851567", "42785560", "42736134", "42786819", "42763211", "42835246", "42793657", "42768181", "42769504", "42823719", "42754188", "42751802", "42747828", "42745422", "42812167", "42749651", "31869068", "31335025", "42728832", "42728670", "42717610", "42709431", "42706121", "42701045", "42697927", "42696218", "42789381", "42774410", "42719177", "42706709", "42688430", "42680537", "42680534", "42819643", "42709592", "42687933", "42830061", "42776587", "42761749" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "targets": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (SPRINT[ti] OR ESPRIT[ti] OR BPROAD[ti] OR \"intensive blood\"[ti] OR \"blood pressure target\"[ti] OR \"blood-pressure target\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti]) AND (SPRINT[ti] OR ESPRIT[ti] OR BPROAD[ti] OR \"intensive blood\"[ti] OR \"blood pressure target\"[ti] OR \"blood-pressure target\"[ti])", "count": 9, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND (\"SPRINT\"[Title] OR \"ESPRIT\"[Title] OR \"BPROAD\"[Title] OR \"intensive blood\"[Title] OR \"blood-pressure target\"[Title] OR \"blood-pressure target\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42837286", "42820977", "42816633", "42803522", "42788285", "42762428", "42749883", "42693262", "42740560" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "lifestyle": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (\"salt substitute\"[tiab] OR \"sodium reduction\"[ti] OR DASH[ti] OR \"potassium\"[ti] AND (salt[ti] OR sodium[ti] OR hypertension[ti]))) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti]) AND (\"salt substitute\"[tiab] OR \"sodium reduction\"[ti] OR DASH[ti] OR \"potassium\"[ti] AND (salt[ti] OR sodium[ti] OR hypertension[ti]))", "count": 5, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND ((\"salt substitute\"[Title/Abstract] OR \"sodium reduction\"[Title] OR \"DASH\"[Title] OR \"potassium\"[Title]) AND (\"salt\"[Title] OR \"sodium\"[Title] OR \"hypertension\"[Title])) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42849839", "42856673", "42744842", "42716956", "42780603" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "new_drugs": { "datetype": "edat", "query": "((baxdrostat[tiab] OR lorundrostat[tiab] OR zilebesiran[tiab] OR aprocitentan[tiab] OR \"aldosterone synthase inhibitor\"[tiab] OR ocedurenone[tiab] OR vicadrostat[tiab])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(baxdrostat[tiab] OR lorundrostat[tiab] OR zilebesiran[tiab] OR aprocitentan[tiab] OR \"aldosterone synthase inhibitor\"[tiab] OR ocedurenone[tiab] OR vicadrostat[tiab])", "count": 23, "translation": "(\"baxdrostat\"[Title/Abstract] OR \"lorundrostat\"[Title/Abstract] OR \"zilebesiran\"[Title/Abstract] OR \"aprocitentan\"[Title/Abstract] OR \"aldosterone synthase inhibitor\"[Title/Abstract] OR \"ocedurenone\"[Title/Abstract] OR \"vicadrostat\"[Title/Abstract]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42837221", "42837060", "42832922", "42826060", "42847230", "42847228", "42847227", "42847226", "42847224", "42847220", "42810479", "42809094", "42778148", "42775984", "42747486", "42709045", "42795360", "42704049", "42757615", "42724901", "42707992", "42774785", "42748315" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "resistant": { "datetype": "edat", "query": "((\"resistant hypertension\"[ti] OR \"treatment-resistant hypertension\"[ti] OR \"refractory hypertension\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(\"resistant hypertension\"[ti] OR \"treatment-resistant hypertension\"[ti] OR \"refractory hypertension\"[ti])", "count": 22, "translation": "(\"resistant hypertension\"[Title] OR \"treatment-resistant hypertension\"[Title] OR \"refractory hypertension\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42855522", "42831847", "42826060", "42847226", "42847224", "42847222", "42847220", "42821518", "42814264", "42811075", "42802228", "42776589", "42765880", "42769504", "42798477", "42708516", "42795360", "42783050", "42757615", "42707992", "42701458", "42769561" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "devices": { "datetype": "edat", "query": "((\"renal denervation\"[ti] OR \"renal sympathetic denervation\"[tiab] OR \"baroreflex activation\"[ti] OR \"ultrasound renal\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(\"renal denervation\"[ti] OR \"renal sympathetic denervation\"[tiab] OR \"baroreflex activation\"[ti] OR \"ultrasound renal\"[ti])", "count": 17, "translation": "(\"renal denervation\"[Title] OR \"renal sympathetic denervation\"[Title/Abstract] OR \"baroreflex activation\"[Title] OR \"ultrasound renal\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42860163", "42855522", "42851099", "42846707", "42730399", "42802228", "42788623", "42781565", "42763807", "42745542", "42783050", "42736942", "42707347", "42681840", "42807709", "42769561", "42770069" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "pregnancy": { "datetype": "edat", "query": "(((hypertension[ti] OR \"blood pressure\"[ti]) AND (pregnan*[ti] OR preeclampsia[ti] OR \"pre-eclampsia\"[ti] OR postpartum[ti] OR gestational[ti]))) AND 2026/09/01:2026/10/12[edat]", "topic_term": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (pregnan*[ti] OR preeclampsia[ti] OR \"pre-eclampsia\"[ti] OR postpartum[ti] OR gestational[ti]))", "count": 49, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND (\"pregnan*\"[Title] OR \"preeclampsia\"[Title] OR \"pre-eclampsia\"[Title] OR \"postpartum\"[Title] OR \"gestational\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42834212", "42856870", "42840939", "42852502", "42838004", "42830508", "42829210", "42856648", "42817173", "42811848", "42769471", "42810469", "42810253", "42776470", "42776108", "42786879", "42767560", "42763987", "42796412", "42777468", "42753491", "42749188", "42747425", "42714460", "42752715", "42736572", "42731374", "42730887", "42734989", "42721368", "42710173", "42710170", "42693441", "42828039", "42819654", "42818950", "42701451", "42688712", "42688579", "42687220", "42829730", "42695459", "42801260", "42797250", "42679444", "42809881", "42724703", "42800413", "42800990" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "special_pops": { "datetype": "edat", "query": "((hypertension[ti] OR antihypertensive[ti]) AND (frail*[ti] OR deprescrib*[ti] OR \"nursing home\"[ti] OR \"chronic kidney\"[ti] OR dialysis[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR antihypertensive[ti]) AND (frail*[ti] OR deprescrib*[ti] OR \"nursing home\"[ti] OR \"chronic kidney\"[ti] OR dialysis[ti])", "count": 20, "translation": "(\"hypertension\"[Title] OR \"antihypertensive\"[Title]) AND (\"frail*\"[Title] OR \"deprescrib*\"[Title] OR \"nursing home\"[Title] OR \"chronic kidney\"[Title] OR \"dialysis\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42855237", "42854921", "42853207", "42844672", "42821184", "42730465", "42687043", "42816154", "42813280", "42782549", "42778148", "42771168", "42775984", "42754276", "42735608", "42712144", "42704541", "42812504", "42707992", "42679503" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "implementation": { "datetype": "edat", "query": "(hypertension[ti] AND (adherence[ti] OR implementation[ti] OR \"community health worker\"[tiab] OR polypill[ti] OR \"task shifting\"[ti] OR \"team-based\"[ti] OR \"village doctor\"[tiab])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "hypertension[ti] AND (adherence[ti] OR implementation[ti] OR \"community health worker\"[tiab] OR polypill[ti] OR \"task shifting\"[ti] OR \"team-based\"[ti] OR \"village doctor\"[tiab])", "count": 21, "translation": "\"hypertension\"[Title] AND (\"adherence\"[Title] OR \"implementation\"[Title] OR \"community health worker\"[Title/Abstract] OR \"polypill\"[Title] OR \"task shifting\"[Title] OR \"team-based\"[Title] OR \"village doctor\"[Title/Abstract]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42761219", "42855528", "42855525", "42850965", "42847222", "42733884", "42856673", "42825182", "42810479", "42767847", "42764987", "42736808", "42722540", "42716957", "42793442", "42708621", "42783050", "42693929", "42694326", "42676786", "42775143" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "emergencies": { "datetype": "edat", "query": "((\"hypertensive emergency\"[ti] OR \"hypertensive emergencies\"[ti] OR \"hypertensive crisis\"[ti] OR \"malignant hypertension\"[ti] OR \"hypertensive urgency\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(\"hypertensive emergency\"[ti] OR \"hypertensive emergencies\"[ti] OR \"hypertensive crisis\"[ti] OR \"malignant hypertension\"[ti] OR \"hypertensive urgency\"[ti])", "count": 14, "translation": "(\"hypertensive emergency\"[Title] OR \"hypertensive emergencies\"[Title] OR \"hypertensive crisis\"[Title] OR \"malignant hypertension\"[Title] OR \"hypertensive urgency\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42844194", "42838972", "42771329", "42830886", "42732683", "42704439", "42700009", "42686811", "42788430", "42792642", "42770127", "42694147", "42709661", "42719902" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "guidelines": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti] OR \"arterial hypertension\"[ti]) AND (guideline[ti] OR \"practice guideline\"[pt] OR \"position statement\"[ti] OR \"consensus statement\"[ti] OR \"scientific statement\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti] OR \"arterial hypertension\"[ti]) AND (guideline[ti] OR \"practice guideline\"[pt] OR \"position statement\"[ti] OR \"consensus statement\"[ti] OR \"scientific statement\"[ti])", "count": 5, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title] OR \"arterial hypertension\"[Title]) AND (\"guideline\"[Title] OR \"practice guideline\"[Publication Type] OR \"position statement\"[Title] OR \"consensus statement\"[Title] OR \"scientific statement\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42858041", "42849428", "42756877", "42688995", "42740758" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "patient": { "datetype": "edat", "query": "(hypertension[ti] AND (qualitative[ti] OR \"patient experience\"[tiab] OR \"lived experience\"[tiab] OR stigma[ti] OR \"treatment burden\"[tiab] OR \"patient-reported\"[ti])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "hypertension[ti] AND (qualitative[ti] OR \"patient experience\"[tiab] OR \"lived experience\"[tiab] OR stigma[ti] OR \"treatment burden\"[tiab] OR \"patient-reported\"[ti])", "count": 12, "translation": "\"hypertension\"[Title] AND (\"qualitative\"[Title] OR \"patient experience\"[Title/Abstract] OR \"lived experience\"[Title/Abstract] OR \"stigma\"[Title] OR \"treatment burden\"[Title/Abstract] OR \"patient-reported\"[Title]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42824628", "42853857", "42847216", "42851994", "42782549", "42796375", "42730029", "42780284", "42774473", "42693929", "42694326", "42713576" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "retractions": { "datetype": "edat", "query": "((hypertension[ti] OR \"blood pressure\"[ti]) AND (\"Retracted Publication\"[pt] OR \"Retraction of Publication\"[pt] OR \"Expression of Concern\"[pt])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(hypertension[ti] OR \"blood pressure\"[ti]) AND (\"Retracted Publication\"[pt] OR \"Retraction of Publication\"[pt] OR \"Expression of Concern\"[pt])", "count": 1, "translation": "(\"hypertension\"[Title] OR \"blood pressure\"[Title]) AND (\"Retracted Publication\"[Publication Type] OR \"Expression of Concern\"[Publication Type]) AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42719959" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": { "phrasesignored": [], "quotedphrasesnotfound": [ "\"Retraction of Publication\"[pt]" ], "outputmessages": [] }, "error": null }, "jsh_chinese_nice": { "datetype": "edat", "query": "(((\"Japanese Society of Hypertension\"[tiab] OR \"JSH 2025\"[tiab] OR \"Chinese guideline\"[ti] AND hypertension[tiab] OR \"NG136\"[tiab] OR \"Hypertension Canada\"[tiab] OR \"Endocrine Society\"[ti] AND aldosteronism[tiab]))) AND 2026/09/01:2026/10/12[edat]", "topic_term": "((\"Japanese Society of Hypertension\"[tiab] OR \"JSH 2025\"[tiab] OR \"Chinese guideline\"[ti] AND hypertension[tiab] OR \"NG136\"[tiab] OR \"Hypertension Canada\"[tiab] OR \"Endocrine Society\"[ti] AND aldosteronism[tiab]))", "count": 1, "translation": "(((\"Japanese Society of Hypertension\"[Title/Abstract] OR \"JSH 2025\"[Title/Abstract] OR \"Chinese guideline\"[Title]) AND \"hypertension\"[Title/Abstract]) OR \"NG136\"[Title/Abstract] OR \"Hypertension Canada\"[Title/Abstract] OR \"Endocrine Society\"[Title]) AND \"aldosteronism\"[Title/Abstract] AND 2026/09/01:2026/10/12[Date - Entry]", "pmids_returned": [ "42680534" ], "retmax_note": "broad_* queries used retmax 20; other topics retmax 150. count is the Entrez count, which can exceed pmids_returned.", "http": 200, "warning": null, "error": null }, "outcome_trials_named": { "datetype": "edat", "query": "((baxdrostat[tiab] OR zilebesiran[tiab] OR lorundrostat[tiab] OR \"renal denervation\"[ti] OR \"salt substitute\"[tiab] OR CHAP[ti] OR \"primary aldosteronism\"[ti]) AND (randomized[tiab] OR randomised[tiab] OR trial[ti] OR guideline[ti] OR \"phase 3\"[tiab] OR \"phase III\"[tiab])) AND 2026/09/01:2026/10/12[edat]", "topic_term": "(baxdrostat[tiab] OR zilebesiran[tiab] OR lorundrostat[tiab] OR \"renal denervation\"[ti] OR \"salt substitute\"[tiab] OR CHAP[ti] OR \"primary aldosteronism\"[ti]) AND (randomized[tiab] OR randomised[tiab] OR trial[ti] OR guideline[ti] OR \"phase 3\"[tiab] 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"nctId": "NCT05414526", "briefTitle": "Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)", "officialTitle": "Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)", "acronym": "InterCARE", "overallStatus": "COMPLETED", "lastUpdate": { "date": "2026-05-12", "type": "ACTUAL" }, "resultsFirst": null, "start": { "date": "2023-01-31", "type": "ACTUAL" }, "primaryCompletion": { "date": "2025-09-10", "type": "ACTUAL" }, "completion": { "date": "2025-09-10", "type": "ACTUAL" }, "enrollment": { "count": 4655, "type": "ACTUAL" }, "phases": [ "NA" ], "studyType": "INTERVENTIONAL", "hasResults": false }, "NCT05732727": { "http": 200, "nctId": "NCT05732727", "briefTitle": "Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease", "officialTitle": "Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease: an Open Label, a Cluster Randomized Controlled, Phase 3 Trial", "acronym": "THINK", "overallStatus": "RECRUITING", "lastUpdate": { "date": "2026-08-03", "type": "ACTUAL" }, "resultsFirst": null, "start": { "date": "2023-03-28", "type": "ACTUAL" }, "primaryCompletion": { "date": "2029-03", "type": "ESTIMATED" }, "completion": { "date": "2029-03", "type": "ESTIMATED" }, "enrollment": { "count": 720, "type": "ESTIMATED" }, "phases": [ "PHASE3" ], "studyType": "INTERVENTIONAL", "hasResults": false } }, "query_term_searches_2026-10-12": { "note": "API v2 studies response contained a studies array and no totalCount field.", "CONSEP": "empty studies array", "enalapril hydrochlorothiazide postpartum hypertension": "empty studies array", "lorundrostat CKD": "NCT06150924 COMPLETED" } }, "guidelines_and_statistics_pages_checked": { "nice_ng136": "https://www.nice.org.uk/guidance/ng136 HTTP 200 on 2026-10-12. Page text contains Published 28 August 2019 and Last updated 26 February 2026.", "who_fact_sheet": "https://www.who.int/news-room/fact-sheets/detail/hypertension HTTP 200. dateModified 2025-09-25. Page still states 1.4 billion. No PMID. Not added as a new statistic. The wiki headline remains the 2019 NCD-RisC figure." }, "triage": { "added": 17, "landmark_note": "none", "not_added_examples": [ "Secondary meta-analyses of baxdrostat, lorundrostat and zilebesiran that re-summarise trials already in the wiki", "Stroke and intracerebral-haemorrhage blood-pressure papers (out of scope; owned by stroke)", "Pulmonary hypertension, including the Brazilian pulmonary hypertension guideline and PAH burden papers", "PMID 42719959 expression of concern; the original paper is not cited here", "QUADRO correction PMID 42708516; QUADRO is not cited in the wiki", "Most primary papers in the 460-PMID summary set: small trials, narrative reviews, letters, case reports", "Europe PMC non-MEDLINE preprints without a resolved PMID were not cited" ] } }