{ "condition": "generalized-anxiety-disorder", "sweep_date": "2026-10-31", "author": "Grok grok-4.6", "window": { "date_from": "2026-10-24", "date_to": "2026-10-31", "primary": "pdat", "supplement": "edat broad, instruments, CDSR, Anxiety Disorders[majr]" }, "sources_queried": [ "PubMed E-utilities esearch/efetch", "Europe PMC REST /search and /fullTextXML", "Crossref /works/{doi} and query.bibliographic (no mailto)", "ClinicalTrials.gov v2 /studies/{NCT} and date-filtered /studies", "ISRCTN XML API /api/trial/{id}/format/default and /api/query/format/default", "WHO ICTRP portal page (JS; not a completed trial search)", "ChiCTR search page (compressed/unusable)", "NICE CG113, APA guidelines, AWMF register, WHO anxiety fact sheet", "ADAA, Mind, NAMI, Anxiety Canada, Anxiety UK, SADAG" ], "sources_not_queried": [ "Cochrane Library/CENTRAL (HTTP 403)", "SciELO/LILACS (HTTP 403)", "Unpaywall (LIFEBANK_CONTACT_EMAIL unset)", "OpenAlex", "DOAJ", "Embase/Scopus/Web of Science" ], "pubmed": [ { "topic": "overview", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\")", "datetype": "pdat", "count": "12", "idlist": [ "42961314", "42961250", "42960975", "42960624", "42959527", "42946258", "42944768", "42937060", "42934775", "42934491", "42932137", "42928507" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "diagnosis-boundary", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (diagnos* OR classification OR criteria OR excessiveness OR uncontrollab* OR taxometric*)", "datetype": "pdat", "count": "5", "idlist": [ "42961250", "42960975", "42937060", "42932137", "42928507" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"diagnos*\"[All Fields] OR (\"classification\"[MeSH Terms] OR \"classification\"[All Fields] OR \"classifications\"[All Fields] OR \"classification\"[MeSH Subheading] OR \"classification s\"[All Fields] OR \"classificator\"[All Fields] OR \"classificators\"[All Fields]) OR (\"criteria s\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[MeSH Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]) OR \"excessiveness\"[All Fields] OR \"uncontrollab*\"[All Fields] OR \"taxometric*\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "epidemiology-burden", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (prevalence OR incidence OR epidemiolog* OR burden OR mortality OR \"treatment gap\")", "datetype": "pdat", "count": "8", "idlist": [ "42961314", "42961250", "42960624", "42959527", "42946258", "42934491", "42932137", "42928507" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR \"epidemiolog*\"[All Fields] OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR \"treatment gap\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "mechanism", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (worry OR \"intolerance of uncertainty\" OR neuroimaging OR fMRI OR HRV OR inflammation OR genetic* OR GWAS)", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"worried\"[All Fields] OR \"worries\"[All Fields] OR \"worry\"[All Fields] OR \"worrying\"[All Fields] OR \"intolerance of uncertainty\"[All Fields] OR (\"neuroimage\"[All Fields] OR \"neuroimaged\"[All Fields] OR \"neuroimagers\"[All Fields] OR \"neuroimages\"[All Fields] OR \"neuroimaging\"[MeSH Terms] OR \"neuroimaging\"[All Fields] OR \"neuroimagings\"[All Fields]) OR (\"magnetic resonance imaging\"[MeSH Terms] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields] AND \"imaging\"[All Fields]) OR \"magnetic resonance imaging\"[All Fields] OR \"fmri\"[All Fields]) OR \"HRV\"[All Fields] OR (\"inflammation\"[MeSH Terms] OR \"inflammation\"[All Fields] OR \"inflammations\"[All Fields] OR \"inflammation s\"[All Fields]) OR \"genetic*\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields])) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "screening-measurement", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (GAD-7 OR GAD-2 OR \"HAM-A\" OR PSWQ OR screening OR psychometric* OR \"measurement-based\")", "datetype": "pdat", "count": "10", "idlist": [ "42961314", "42960975", "42960624", "42959527", "42946258", "42944768", "42937060", "42934775", "42934491", "42932137" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"patient health questionnaire\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"health\"[All Fields] AND \"questionnaire\"[All Fields]) OR \"patient health questionnaire\"[All Fields] OR \"gad 7\"[All Fields] OR (\"patient health questionnaire\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"health\"[All Fields] AND \"questionnaire\"[All Fields]) OR \"patient health questionnaire\"[All Fields] OR \"gad 2\"[All Fields]) OR \"HAM-A\"[All Fields] OR \"PSWQ\"[All Fields] OR (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields]) OR \"psychometric*\"[All Fields] OR \"measurement-based\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "cbt", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (\"cognitive behav*\" OR CBT OR \"applied relaxation\")", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"cognitive behav*\"[All Fields] OR \"CBT\"[All Fields] OR \"applied relaxation\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "other-psych", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (metacognitive OR mindfulness OR MBSR OR \"acceptance and commitment\" OR psychodynamic OR exercise OR acupuncture OR phytoceutical*)", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"metacognition\"[MeSH Terms] OR \"metacognition\"[All Fields] OR \"metacognitions\"[All Fields] OR \"metacognitive\"[All Fields] OR \"metacognitively\"[All Fields] OR (\"mind s\"[All Fields] OR \"minded\"[All Fields] OR \"mindful\"[All Fields] OR \"mindfulness\"[MeSH Terms] OR \"mindfulness\"[All Fields] OR \"minding\"[All Fields] OR \"minds\"[All Fields]) OR \"MBSR\"[All Fields] OR \"acceptance and commitment\"[All Fields] OR (\"psychodynamic\"[All Fields] OR \"psychodynamical\"[All Fields] OR \"psychodynamically\"[All Fields] OR \"psychodynamics\"[All Fields]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"acupunctural\"[All Fields] OR \"acupuncture\"[MeSH Terms] OR \"acupuncture\"[All Fields] OR \"acupuncture therapy\"[MeSH Terms] OR (\"acupuncture\"[All Fields] AND \"therapy\"[All Fields]) OR \"acupuncture therapy\"[All Fields] OR \"acupuncture s\"[All Fields] OR \"acupunctured\"[All Fields] OR \"acupunctures\"[All Fields] OR \"acupuncturing\"[All Fields]) OR \"phytoceutical*\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "ssri-snri", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (SSRI OR SNRI OR escitalopram OR sertraline OR venlafaxine OR duloxetine OR paroxetine OR antidepressant*)", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields]) OR (\"serotonin and noradrenaline reuptake inhibitors\"[Pharmacological Action] OR \"serotonin and noradrenaline reuptake inhibitors\"[Supplementary Concept] OR \"serotonin and noradrenaline reuptake inhibitors\"[All Fields] OR \"snri\"[All Fields] OR \"serotonin and noradrenaline reuptake inhibitors\"[MeSH Terms] OR (\"serotonin\"[All Fields] AND \"noradrenaline\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"escitalopram\"[Supplementary Concept] OR \"escitalopram\"[All Fields] OR \"escitalopram\"[MeSH Terms] OR \"escitalopram s\"[All Fields]) OR (\"sertralin\"[All Fields] OR \"sertraline\"[Supplementary Concept] OR \"sertraline\"[All Fields] OR \"sertraline\"[MeSH Terms] OR \"sertraline s\"[All Fields]) OR (\"venlafaxin\"[All Fields] OR \"venlafaxine hydrochloride\"[Supplementary Concept] OR \"venlafaxine hydrochloride\"[All Fields] OR \"venlafaxine\"[All Fields] OR \"venlafaxine hydrochloride\"[MeSH Terms] OR (\"venlafaxine\"[All Fields] AND \"hydrochloride\"[All Fields])) OR (\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine s\"[All Fields]) OR (\"paroxetin\"[All Fields] OR \"paroxetine\"[Supplementary Concept] OR \"paroxetine\"[All Fields] OR \"paroxetine\"[MeSH Terms] OR \"paroxetine s\"[All Fields]) OR \"antidepressant*\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "other-drugs", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (pregabalin OR benzodiazepine* OR quetiapine OR buspirone OR agomelatine OR silexan OR cannabidiol OR hydroxyzine)", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields] OR \"benzodiazepine*\"[All Fields] OR (\"quetiapin\"[All Fields] OR \"quetiapine fumarate\"[Supplementary Concept] OR \"quetiapine fumarate\"[All Fields] OR \"quetiapine\"[All Fields] OR \"quetiapine fumarate\"[MeSH Terms] OR (\"quetiapine\"[All Fields] AND \"fumarate\"[All Fields]) OR \"quetiapine s\"[All Fields]) OR (\"buspirone\"[Supplementary Concept] OR \"buspirone\"[All Fields] OR \"buspiron\"[All Fields] OR \"buspirone\"[MeSH Terms] OR \"buspirone s\"[All Fields]) OR (\"agomelatin\"[All Fields] OR \"agomelatine\"[Supplementary Concept] OR \"agomelatine\"[All Fields] OR \"agomelatine s\"[All Fields]) OR (\"lavender oil\"[Supplementary Concept] OR \"lavender oil\"[All Fields] OR \"silexan\"[All Fields]) OR (\"cannabidiol\"[Supplementary Concept] OR \"cannabidiol\"[All Fields] OR \"cannabidiol\"[MeSH Terms] OR \"cannabidiolic\"[All Fields]) OR (\"hydroxyzine\"[Supplementary Concept] OR \"hydroxyzine\"[All Fields] OR \"hydroxyzine\"[MeSH Terms])) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "digital", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (internet OR iCBT OR app OR digital OR \"conversational agent\" OR chatbot OR tele*)", "datetype": "pdat", "count": "3", "idlist": [ "42961314", "42944768", "42934775" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"internet\"[MeSH Terms] OR \"internet\"[All Fields] OR \"internet s\"[All Fields] OR \"internets\"[All Fields] OR \"iCBT\"[All Fields] OR (\"australas plant pathol\"[Journal] OR \"app\"[All Fields]) OR (\"digitalisation\"[All Fields] OR \"digitalised\"[All Fields] OR \"digitalization\"[All Fields] OR \"digitalize\"[All Fields] OR \"digitalized\"[All Fields] OR \"digitalizer\"[All Fields] OR \"digitalizing\"[All Fields] OR \"digitally\"[All Fields] OR \"digitals\"[All Fields] OR \"digitization\"[All Fields] OR \"digitizations\"[All Fields] OR \"digitize\"[All Fields] OR \"digitized\"[All Fields] OR \"digitizer\"[All Fields] OR \"digitizers\"[All Fields] OR \"digitizes\"[All Fields] OR \"digitizing\"[All Fields] OR \"radiographic image enhancement\"[MeSH Terms] OR (\"radiographic\"[All Fields] AND \"image\"[All Fields] AND \"enhancement\"[All Fields]) OR \"radiographic image enhancement\"[All Fields] OR \"digital\"[All Fields]) OR \"conversational agent\"[All Fields] OR (\"generative artificial intelligence\"[MeSH Terms] OR (\"generative\"[All Fields] AND \"artificial\"[All Fields] AND \"intelligence\"[All Fields]) OR \"generative artificial intelligence\"[All Fields] OR \"chatbot\"[All Fields]) OR \"tele*\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "resistant-pipeline", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (\"treatment-resistant\" OR augmentation OR rTMS OR ketamine OR psychedelic OR ulotaront OR \"MM120\" OR \"ITI-1284\" OR pipeline)", "datetype": "pdat", "count": "1", "idlist": [ "42960975" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"treatment-resistant\"[All Fields] OR (\"augment\"[All Fields] OR \"augmentation\"[All Fields] OR \"augmentations\"[All Fields] OR \"augmented\"[All Fields] OR \"augmenting\"[All Fields] OR \"augments\"[All Fields]) OR (\"transcranial magnetic stimulation\"[MeSH Terms] OR (\"transcranial\"[All Fields] AND \"magnetic\"[All Fields] AND \"stimulation\"[All Fields]) OR \"transcranial magnetic stimulation\"[All Fields] OR \"rtms\"[All Fields]) OR (\"ketamin\"[All Fields] OR \"ketamine\"[Supplementary Concept] OR \"ketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"ketamine\"[MeSH Terms] OR \"ketamine s\"[All Fields] OR \"ketamines\"[All Fields]) OR (\"hallucinogens\"[Pharmacological Action] OR \"hallucinogens\"[Supplementary Concept] OR \"hallucinogens\"[All Fields] OR \"psychedelic\"[All Fields] OR \"hallucinogens\"[MeSH Terms] OR \"psychedelics\"[All Fields]) OR (\"sep 363856\"[Supplementary Concept] OR \"sep 363856\"[All Fields] OR \"ulotaront\"[All Fields]) OR \"MM120\"[All Fields] OR (\"pipeline\"[All Fields] OR \"pipeline s\"[All Fields] OR \"pipelined\"[All Fields] OR \"pipelines\"[All Fields] OR \"pipelining\"[All Fields])) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "course-relapse", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (course OR relapse OR remission OR prognosis OR \"long-term\")", "datetype": "pdat", "count": "2", "idlist": [ "42959527", "42934775" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"course\"[All Fields] OR \"course s\"[All Fields] OR \"courses\"[All Fields] OR (\"recurrence\"[MeSH Terms] OR \"recurrence\"[All Fields] OR \"relapse\"[All Fields] OR \"relapses\"[All Fields] OR \"relapsing\"[All Fields] OR \"relapsed\"[All Fields] OR \"relapser\"[All Fields] OR \"relapsers\"[All Fields]) OR (\"remission\"[All Fields] OR \"remissions\"[All Fields]) OR (\"prognosis\"[MeSH Terms] OR \"prognosis\"[All Fields] OR \"prognoses\"[All Fields]) OR \"long-term\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "special-populations", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (child* OR adolescen* OR pediatric OR perinatal OR pregnan* OR \"older adult*\" OR geriatric OR veteran*)", "datetype": "pdat", "count": "3", "idlist": [ "42961314", "42959527", "42946258" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"child*\"[All Fields] OR \"adolescen*\"[All Fields] OR (\"paediatrics\"[All Fields] OR \"pediatrics\"[MeSH Terms] OR \"pediatrics\"[All Fields] OR \"paediatric\"[All Fields] OR \"pediatric\"[All Fields]) OR (\"perinatal\"[All Fields] OR \"perinatally\"[All Fields] OR \"perinatals\"[All Fields]) OR \"pregnan*\"[All Fields] OR \"older adult*\"[All Fields] OR (\"geriatric\"[All Fields] OR \"geriatrics\"[MeSH Terms] OR \"geriatrics\"[All Fields]) OR \"veteran*\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "comorbidity-pc", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (comorbid* OR \"primary care\" OR depression OR \"substance use\" OR collaborative)", "datetype": "pdat", "count": "11", "idlist": [ "42961314", "42961250", "42960975", "42960624", "42959527", "42946258", "42944768", "42937060", "42934491", "42932137", "42928507" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"comorbid*\"[All Fields] OR \"primary care\"[All Fields] OR (\"depressed\"[All Fields] OR \"depression\"[MeSH Terms] OR \"depression\"[All Fields] OR \"depressions\"[All Fields] OR \"depression s\"[All Fields] OR \"depressive disorder\"[MeSH Terms] OR (\"depressive\"[All Fields] AND \"disorder\"[All Fields]) OR \"depressive disorder\"[All Fields] OR \"depressivity\"[All Fields] OR \"depressive\"[All Fields] OR \"depressively\"[All Fields] OR \"depressiveness\"[All Fields] OR \"depressives\"[All Fields]) OR \"substance use\"[All Fields] OR (\"collaborate\"[All Fields] OR \"collaborated\"[All Fields] OR \"collaborates\"[All Fields] OR \"collaborating\"[All Fields] OR \"collaboration\"[All Fields] OR \"collaborations\"[All Fields] OR \"collaborative\"[All Fields] OR \"collaborative s\"[All Fields] OR \"collaboratively\"[All Fields] OR \"collaboratives\"[All Fields] OR \"collaborator\"[All Fields] OR \"collaborators\"[All Fields])) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "guidelines-safety-voice", "kind": "topic", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (guideline* OR \"practice guideline\" OR suicid* OR safety OR \"patient experience\" OR qualitative OR advocacy)", "datetype": "pdat", "count": "2", "idlist": [ "42960975", "42937060" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"guideline*\"[All Fields] OR \"practice guideline\"[All Fields] OR \"suicid*\"[All Fields] OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR \"patient experience\"[All Fields] OR (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]) OR (\"advocacies\"[All Fields] OR \"advocacy\"[All Fields] OR \"advocacy s\"[All Fields])) AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "overview", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "diagnosis-boundary", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (diagnos* OR classification OR criteria OR excessiveness OR uncontrollab* OR taxometric*) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"diagnos*\"[All Fields] OR (\"classification\"[MeSH Terms] OR \"classification\"[All Fields] OR \"classifications\"[All Fields] OR \"classification\"[MeSH Subheading] OR \"classification s\"[All Fields] OR \"classificator\"[All Fields] OR \"classificators\"[All Fields]) OR (\"criteria s\"[All Fields] OR \"criterias\"[All Fields] OR \"standards\"[MeSH Subheading] OR \"standards\"[All Fields] OR \"criteria\"[All Fields]) OR \"excessiveness\"[All Fields] OR \"uncontrollab*\"[All Fields] OR \"taxometric*\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "epidemiology-burden", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (prevalence OR incidence OR epidemiolog* OR burden OR mortality OR \"treatment gap\") AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR \"prevalance\"[All Fields] OR \"prevalences\"[All Fields] OR \"prevalence s\"[All Fields] OR \"prevalent\"[All Fields] OR \"prevalently\"[All Fields] OR \"prevalents\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR \"epidemiolog*\"[All Fields] OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR \"treatment gap\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "mechanism", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (worry OR \"intolerance of uncertainty\" OR neuroimaging OR fMRI OR HRV OR inflammation OR genetic* OR GWAS) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"worried\"[All Fields] OR \"worries\"[All Fields] OR \"worry\"[All Fields] OR \"worrying\"[All Fields] OR \"intolerance of uncertainty\"[All Fields] OR (\"neuroimage\"[All Fields] OR \"neuroimaged\"[All Fields] OR \"neuroimagers\"[All Fields] OR \"neuroimages\"[All Fields] OR \"neuroimaging\"[MeSH Terms] OR \"neuroimaging\"[All Fields] OR \"neuroimagings\"[All Fields]) OR (\"magnetic resonance imaging\"[MeSH Terms] OR (\"magnetic\"[All Fields] AND \"resonance\"[All Fields] AND \"imaging\"[All Fields]) OR \"magnetic resonance imaging\"[All Fields] OR \"fmri\"[All Fields]) OR \"HRV\"[All Fields] OR (\"inflammation\"[MeSH Terms] OR \"inflammation\"[All Fields] OR \"inflammations\"[All Fields] OR \"inflammation s\"[All Fields]) OR \"genetic*\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields])) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "screening-measurement", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (GAD-7 OR GAD-2 OR \"HAM-A\" OR PSWQ OR screening OR psychometric* OR \"measurement-based\") AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"patient health questionnaire\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"health\"[All Fields] AND \"questionnaire\"[All Fields]) OR \"patient health questionnaire\"[All Fields] OR \"gad 7\"[All Fields] OR (\"patient health questionnaire\"[MeSH Terms] OR (\"patient\"[All Fields] AND \"health\"[All Fields] AND \"questionnaire\"[All Fields]) OR \"patient health questionnaire\"[All Fields] OR \"gad 2\"[All Fields]) OR \"HAM-A\"[All Fields] OR \"PSWQ\"[All Fields] OR (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields]) OR \"psychometric*\"[All Fields] OR \"measurement-based\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "cbt", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (\"cognitive behav*\" OR CBT OR \"applied relaxation\") AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"cognitive behav*\"[All Fields] OR \"CBT\"[All Fields] OR \"applied relaxation\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "other-psych", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (metacognitive OR mindfulness OR MBSR OR \"acceptance and commitment\" OR psychodynamic OR exercise OR acupuncture OR phytoceutical*) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"metacognition\"[MeSH Terms] OR \"metacognition\"[All Fields] OR \"metacognitions\"[All Fields] OR \"metacognitive\"[All Fields] OR \"metacognitively\"[All Fields] OR (\"mind s\"[All Fields] OR \"minded\"[All Fields] OR \"mindful\"[All Fields] OR \"mindfulness\"[MeSH Terms] OR \"mindfulness\"[All Fields] OR \"minding\"[All Fields] OR \"minds\"[All Fields]) OR \"MBSR\"[All Fields] OR \"acceptance and commitment\"[All Fields] OR (\"psychodynamic\"[All Fields] OR \"psychodynamical\"[All Fields] OR \"psychodynamically\"[All Fields] OR \"psychodynamics\"[All Fields]) OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR (\"acupunctural\"[All Fields] OR \"acupuncture\"[MeSH Terms] OR \"acupuncture\"[All Fields] OR \"acupuncture therapy\"[MeSH Terms] OR (\"acupuncture\"[All Fields] AND \"therapy\"[All Fields]) OR \"acupuncture therapy\"[All Fields] OR \"acupuncture s\"[All Fields] OR \"acupunctured\"[All Fields] OR \"acupunctures\"[All Fields] OR \"acupuncturing\"[All Fields]) OR \"phytoceutical*\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "ssri-snri", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (SSRI OR SNRI OR escitalopram OR sertraline OR venlafaxine OR duloxetine OR paroxetine OR antidepressant*) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields]) OR (\"serotonin and noradrenaline reuptake inhibitors\"[Pharmacological Action] OR \"serotonin and noradrenaline reuptake inhibitors\"[Supplementary Concept] OR \"serotonin and noradrenaline reuptake inhibitors\"[All Fields] OR \"snri\"[All Fields] OR \"serotonin and noradrenaline reuptake inhibitors\"[MeSH Terms] OR (\"serotonin\"[All Fields] AND \"noradrenaline\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"escitalopram\"[Supplementary Concept] OR \"escitalopram\"[All Fields] OR \"escitalopram\"[MeSH Terms] OR \"escitalopram s\"[All Fields]) OR (\"sertralin\"[All Fields] OR \"sertraline\"[Supplementary Concept] OR \"sertraline\"[All Fields] OR \"sertraline\"[MeSH Terms] OR \"sertraline s\"[All Fields]) OR (\"venlafaxin\"[All Fields] OR \"venlafaxine hydrochloride\"[Supplementary Concept] OR \"venlafaxine hydrochloride\"[All Fields] OR \"venlafaxine\"[All Fields] OR \"venlafaxine hydrochloride\"[MeSH Terms] OR (\"venlafaxine\"[All Fields] AND \"hydrochloride\"[All Fields])) OR (\"duloxetin\"[All Fields] OR \"duloxetine hydrochloride\"[Supplementary Concept] OR \"duloxetine hydrochloride\"[All Fields] OR \"duloxetine\"[All Fields] OR \"duloxetine hydrochloride\"[MeSH Terms] OR (\"duloxetine\"[All Fields] AND \"hydrochloride\"[All Fields]) OR \"duloxetine s\"[All Fields]) OR (\"paroxetin\"[All Fields] OR \"paroxetine\"[Supplementary Concept] OR \"paroxetine\"[All Fields] OR \"paroxetine\"[MeSH Terms] OR \"paroxetine s\"[All Fields]) OR \"antidepressant*\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "other-drugs", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (pregabalin OR benzodiazepine* OR quetiapine OR buspirone OR agomelatine OR silexan OR cannabidiol OR hydroxyzine) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields] OR \"benzodiazepine*\"[All Fields] OR (\"quetiapin\"[All Fields] OR \"quetiapine fumarate\"[Supplementary Concept] OR \"quetiapine fumarate\"[All Fields] OR \"quetiapine\"[All Fields] OR \"quetiapine fumarate\"[MeSH Terms] OR (\"quetiapine\"[All Fields] AND \"fumarate\"[All Fields]) OR \"quetiapine s\"[All Fields]) OR (\"buspirone\"[Supplementary Concept] OR \"buspirone\"[All Fields] OR \"buspiron\"[All Fields] OR \"buspirone\"[MeSH Terms] OR \"buspirone s\"[All Fields]) OR (\"agomelatin\"[All Fields] OR \"agomelatine\"[Supplementary Concept] OR \"agomelatine\"[All Fields] OR \"agomelatine s\"[All Fields]) OR (\"lavender oil\"[Supplementary Concept] OR \"lavender oil\"[All Fields] OR \"silexan\"[All Fields]) OR (\"cannabidiol\"[Supplementary Concept] OR \"cannabidiol\"[All Fields] OR \"cannabidiol\"[MeSH Terms] OR \"cannabidiolic\"[All Fields]) OR (\"hydroxyzine\"[Supplementary Concept] OR \"hydroxyzine\"[All Fields] OR \"hydroxyzine\"[MeSH Terms])) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "digital", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (internet OR iCBT OR app OR digital OR \"conversational agent\" OR chatbot OR tele*) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"internet\"[MeSH Terms] OR \"internet\"[All Fields] OR \"internet s\"[All Fields] OR \"internets\"[All Fields] OR \"iCBT\"[All Fields] OR (\"australas plant pathol\"[Journal] OR \"app\"[All Fields]) OR (\"digitalisation\"[All Fields] OR \"digitalised\"[All Fields] OR \"digitalization\"[All Fields] OR \"digitalize\"[All Fields] OR \"digitalized\"[All Fields] OR \"digitalizer\"[All Fields] OR \"digitalizing\"[All Fields] OR \"digitally\"[All Fields] OR \"digitals\"[All Fields] OR \"digitization\"[All Fields] OR \"digitizations\"[All Fields] OR \"digitize\"[All Fields] OR \"digitized\"[All Fields] OR \"digitizer\"[All Fields] OR \"digitizers\"[All Fields] OR \"digitizes\"[All Fields] OR \"digitizing\"[All Fields] OR \"radiographic image enhancement\"[MeSH Terms] OR (\"radiographic\"[All Fields] AND \"image\"[All Fields] AND \"enhancement\"[All Fields]) OR \"radiographic image enhancement\"[All Fields] OR \"digital\"[All Fields]) OR \"conversational agent\"[All Fields] OR (\"generative artificial intelligence\"[MeSH Terms] OR (\"generative\"[All Fields] AND \"artificial\"[All Fields] AND \"intelligence\"[All Fields]) OR \"generative artificial intelligence\"[All Fields] OR \"chatbot\"[All Fields]) OR \"tele*\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "resistant-pipeline", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (\"treatment-resistant\" OR augmentation OR rTMS OR ketamine OR psychedelic OR ulotaront OR \"MM120\" OR \"ITI-1284\" OR pipeline) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"treatment-resistant\"[All Fields] OR (\"augment\"[All Fields] OR \"augmentation\"[All Fields] OR \"augmentations\"[All Fields] OR \"augmented\"[All Fields] OR \"augmenting\"[All Fields] OR \"augments\"[All Fields]) OR (\"transcranial magnetic stimulation\"[MeSH Terms] OR (\"transcranial\"[All Fields] AND \"magnetic\"[All Fields] AND \"stimulation\"[All Fields]) OR \"transcranial magnetic stimulation\"[All Fields] OR \"rtms\"[All Fields]) OR (\"ketamin\"[All Fields] OR \"ketamine\"[Supplementary Concept] OR \"ketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"ketamine\"[MeSH Terms] OR \"ketamine s\"[All Fields] OR \"ketamines\"[All Fields]) OR (\"hallucinogens\"[Pharmacological Action] OR \"hallucinogens\"[Supplementary Concept] OR \"hallucinogens\"[All Fields] OR \"psychedelic\"[All Fields] OR \"hallucinogens\"[MeSH Terms] OR \"psychedelics\"[All Fields]) OR (\"sep 363856\"[Supplementary Concept] OR \"sep 363856\"[All Fields] OR \"ulotaront\"[All Fields]) OR \"MM120\"[All Fields] OR (\"pipeline\"[All Fields] OR \"pipeline s\"[All Fields] OR \"pipelined\"[All Fields] OR \"pipelines\"[All Fields] OR \"pipelining\"[All Fields])) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "course-relapse", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (course OR relapse OR remission OR prognosis OR \"long-term\") AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"course\"[All Fields] OR \"course s\"[All Fields] OR \"courses\"[All Fields] OR (\"recurrence\"[MeSH Terms] OR \"recurrence\"[All Fields] OR \"relapse\"[All Fields] OR \"relapses\"[All Fields] OR \"relapsing\"[All Fields] OR \"relapsed\"[All Fields] OR \"relapser\"[All Fields] OR \"relapsers\"[All Fields]) OR (\"remission\"[All Fields] OR \"remissions\"[All Fields]) OR (\"prognosis\"[MeSH Terms] OR \"prognosis\"[All Fields] OR \"prognoses\"[All Fields]) OR \"long-term\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "special-populations", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (child* OR adolescen* OR pediatric OR perinatal OR pregnan* OR \"older adult*\" OR geriatric OR veteran*) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"child*\"[All Fields] OR \"adolescen*\"[All Fields] OR (\"paediatrics\"[All Fields] OR \"pediatrics\"[MeSH Terms] OR \"pediatrics\"[All Fields] OR \"paediatric\"[All Fields] OR \"pediatric\"[All Fields]) OR (\"perinatal\"[All Fields] OR \"perinatally\"[All Fields] OR \"perinatals\"[All Fields]) OR \"pregnan*\"[All Fields] OR \"older adult*\"[All Fields] OR (\"geriatric\"[All Fields] OR \"geriatrics\"[MeSH Terms] OR \"geriatrics\"[All Fields]) OR \"veteran*\"[All Fields]) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "comorbidity-pc", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (comorbid* OR \"primary care\" OR depression OR \"substance use\" OR collaborative) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"comorbid*\"[All Fields] OR \"primary care\"[All Fields] OR (\"depressed\"[All Fields] OR \"depression\"[MeSH Terms] OR \"depression\"[All Fields] OR \"depressions\"[All Fields] OR \"depression s\"[All Fields] OR \"depressive disorder\"[MeSH Terms] OR (\"depressive\"[All Fields] AND \"disorder\"[All Fields]) OR \"depressive disorder\"[All Fields] OR \"depressivity\"[All Fields] OR \"depressive\"[All Fields] OR \"depressively\"[All Fields] OR \"depressiveness\"[All Fields] OR \"depressives\"[All Fields]) OR \"substance use\"[All Fields] OR (\"collaborate\"[All Fields] OR \"collaborated\"[All Fields] OR \"collaborates\"[All Fields] OR \"collaborating\"[All Fields] OR \"collaboration\"[All Fields] OR \"collaborations\"[All Fields] OR \"collaborative\"[All Fields] OR \"collaborative s\"[All Fields] OR \"collaboratively\"[All Fields] OR \"collaboratives\"[All Fields] OR \"collaborator\"[All Fields] OR \"collaborators\"[All Fields])) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "guidelines-safety-voice", "kind": "cochrane", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (guideline* OR \"practice guideline\" OR suicid* OR safety OR \"patient experience\" OR qualitative OR advocacy) AND \"Cochrane Database Syst Rev\"[jour]", "datetype": "pdat", "count": "0", "idlist": [], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND (\"guideline*\"[All Fields] OR \"practice guideline\"[All Fields] OR \"suicid*\"[All Fields] OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR \"patient experience\"[All Fields] OR (\"qualitative\"[All Fields] OR \"qualitatively\"[All Fields] OR \"qualitatives\"[All Fields]) OR (\"advocacies\"[All Fields] OR \"advocacy\"[All Fields] OR \"advocacy s\"[All Fields])) AND \"Cochrane Database Syst Rev\"[Journal] AND 2026/10/24:2026/10/31[Date - Publication]" }, { "topic": "overview", "kind": "edat-broad", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\")", "datetype": "edat", "count": "42", "idlist": [ "42961314", "42961250", "42960975", "42960900", "42960624", "42959822", "42959527", "42959164", "42954061", "42953477", "42952948", "42952940", "42952833", "42952758", "42947780", "42946932", "42946258", "42945439", "42944768", "42940749", "42940471", "42938520", "42937792", "42937060", "42936713", "42934775", "42934491", "42933170", "42932137", "42930214", "42928680", "42928674", "42928507", "42926659", "42925173", "42924883", "42923971", "42923532", "42922003", "42921502", "42920894", "42920559" ], "querytranslation": "(\"generalized anxiety disorder\"[All Fields] OR \"generalised anxiety disorder\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Entry]" }, { "topic": "screening-measurement", "kind": "edat-instruments", "query": "(\"GAD-7\" OR \"GAD-2\" OR \"Hamilton Anxiety\" OR HAM-A OR PSWQ) AND (anxiety OR GAD)", "datetype": "edat", "count": "56", "idlist": [ "42961314", "42960900", "42960624", "42959164", "42959136", "42957392", "42956552", "42955103", "42953409", "42952970", "42952948", "42952940", "42952758", "42948318", "42947595", "42947201", "42947175", "42947157", "42947135", "42947087", "42947071", "42946932", "42946258", "42945441", "42940749", "42940705", "42937199", "42935982", "42935642", "42935561", "42934775", "42934748", "42934454", "42931326", "42931110", "42930214", "42929074", "42928689", "42928680", "42928679", "42928674", "42928194", "42926826", "42926659", "42926157", "42925617", "42925400", "42925173", "42923971", "42923532", "42923288", "42923028", "42921502", "42921351", "42920894", "42920633" ], "querytranslation": "(\"GAD-7\"[All Fields] OR \"GAD-2\"[All Fields] OR \"Hamilton Anxiety\"[All Fields] OR \"HAM-A\"[All Fields] OR \"PSWQ\"[All Fields]) AND (\"anxiety\"[MeSH Terms] OR \"anxiety\"[All Fields] OR \"anxieties\"[All Fields] OR \"anxiety s\"[All Fields] OR \"GAD\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Entry]" }, { "topic": "cochrane-broad", "kind": "cochrane-edat", "query": "\"Cochrane Database Syst Rev\"[jour] AND (anxiety OR anxiolytic OR GAD OR \"generalized anxiety\" OR \"generalised anxiety\")", "datetype": "edat", "count": "1", "idlist": [ "42929381" ], "querytranslation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"anxiety\"[MeSH Terms] OR \"anxiety\"[All Fields] OR \"anxieties\"[All Fields] OR \"anxiety s\"[All Fields] OR (\"anti anxiety agents\"[Pharmacological Action] OR \"anti anxiety agents\"[Supplementary Concept] OR \"anti anxiety agents\"[All Fields] OR \"anxiolytic\"[All Fields] OR \"anti anxiety agents\"[MeSH Terms] OR (\"anti anxiety\"[All Fields] AND \"agents\"[All Fields]) OR \"anxiolytics\"[All Fields]) OR \"GAD\"[All Fields] OR \"generalized anxiety\"[All Fields] OR \"generalised anxiety\"[All Fields]) AND 2026/10/24:2026/10/31[Date - Entry]" }, { "topic": "anxiety-majr", "kind": "edat-majr", "query": "\"Anxiety Disorders\"[majr]", "datetype": "edat", "count": "19", "idlist": [ "42959527", "42958499", "42958495", "42958196", "42958127", "42958031", "42955240", "42947192", "42946731", "42946127", "42945451", "42942501", "42937103", "42936193", "42934604", "42928682", "42928680", "42927343", "42922113" ], "querytranslation": "\"Anxiety Disorders\"[MeSH Major Topic] AND 2026/10/24:2026/10/31[Date - Entry]" } ], "europepmc": [ { "topic": "overview", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 26, "ids": [ { "source": "MED", "id": "42928507", "pmid": "42928507", "doi": "10.1002/eat.70249", "title": "Disordered Eating Behaviors and Comorbid Binge-Eating Disorder in Female Patients With Generalized Anxiety Disorder, Major Depressive Disorder, and Panic Disorder: A Transdiagnostic Approach." }, { "source": "PPR", "id": "PPR1349433", "pmid": null, "doi": "10.64898/2026.10.21.26366048", "title": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis" }, { "source": "MED", "id": "42932137", "pmid": "42932137", "doi": "10.1007/s12306-026-00988-z", "title": "Generalized anxiety disorder may lead to increased healthcare utilization following total hip arthroplasty." }, { "source": "PPR", "id": "PPR1349741", "pmid": null, "doi": "10.12688/wellcomeopenres.26228.1", "title": "Tele-Adaptation and Feasibility of a Brief Yoga Therapy Module for Generalized Anxiety Disorder: A Pilot Study" }, { "source": "MED", "id": "42934491", "pmid": "42934491", "doi": "10.1177/00048674261496100", "title": "Time to face the music: Mental health measures are failing us." }, { "source": "MED", "id": "42937060", "pmid": "42937060", "doi": "10.1097/yco.0000000000001132", "title": "Anxiety and suicide risk: mechanism, timing, and clinical utility." }, { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "PPR", "id": "PPR1353779", "pmid": null, "doi": "10.21203/rs.3.rs-10985453/v1", "title": "Identification of shared blood transcriptomic features and candidate sedative targets in chronic insomnia with comorbid anxiety: an in-silico study" }, { "source": "MED", "id": "42944768", "pmid": "42944768", "doi": "10.1556/2006.2026.00120", "title": "Gaming-related harms and help-seeking experiences across problem gaming risk groups: A cluster profile analysis." }, { "source": "MED", "id": "42946258", "pmid": "42946258", "doi": "10.1016/j.jaclp.2026.10.343", "title": "Depressive and Anxiety symptoms associated with ICU admission in hypertensive disorders of pregnancy: a prospective cohort study." }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "MED", "id": "42952997", "pmid": "42952997", "doi": "10.1098/rsos.252073", "title": "No association between body dissatisfaction and attentional bias towards lower-weight bodies in a non-clinical sample of women: an eye-tracking study. " }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "PMC", "id": "PMC13717537", "pmid": null, "doi": null, "title": "Attention-Deficit/Hyperactivity Disorder With Family Relational Challenges and Persistent Gender-Nonconforming Expression in a Preadolescent Girl: A Case Report" }, { "source": "PMC", "id": "PMC13690424", "pmid": null, "doi": null, "title": "Fulminant Ischemic Colitis With Toxic Megacolon in a Young Man Receiving Testosterone Replacement Therapy Despite Therapeutic Phlebotomy for Hereditary Hemochromatosis: A Case Report" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " }, { "source": "PMC", "id": "PMC13716809", "pmid": null, "doi": null, "title": "Perceived neijuan profiles and problematic short-form video use among Chinese college students: indirect associations through anxiety and escape motivation" } ] }, { "topic": "diagnosis", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (diagnos* OR criteria OR classification) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 22, "ids": [ { "source": "PPR", "id": "PPR1349433", "pmid": null, "doi": "10.64898/2026.10.21.26366048", "title": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis" }, { "source": "PPR", "id": "PPR1349741", "pmid": null, "doi": "10.12688/wellcomeopenres.26228.1", "title": "Tele-Adaptation and Feasibility of a Brief Yoga Therapy Module for Generalized Anxiety Disorder: A Pilot Study" }, { "source": "MED", "id": "42928507", "pmid": "42928507", "doi": "10.1002/eat.70249", "title": "Disordered Eating Behaviors and Comorbid Binge-Eating Disorder in Female Patients With Generalized Anxiety Disorder, Major Depressive Disorder, and Panic Disorder: A Transdiagnostic Approach." }, { "source": "MED", "id": "42932137", "pmid": "42932137", "doi": "10.1007/s12306-026-00988-z", "title": "Generalized anxiety disorder may lead to increased healthcare utilization following total hip arthroplasty." }, { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "MED", "id": "42937060", "pmid": "42937060", "doi": "10.1097/yco.0000000000001132", "title": "Anxiety and suicide risk: mechanism, timing, and clinical utility." }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "MED", "id": "42952997", "pmid": "42952997", "doi": "10.1098/rsos.252073", "title": "No association between body dissatisfaction and attentional bias towards lower-weight bodies in a non-clinical sample of women: an eye-tracking study. " }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13716809", "pmid": null, "doi": null, "title": "Perceived neijuan profiles and problematic short-form video use among Chinese college students: indirect associations through anxiety and escape motivation" }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "PMC", "id": "PMC13717537", "pmid": null, "doi": null, "title": "Attention-Deficit/Hyperactivity Disorder With Family Relational Challenges and Persistent Gender-Nonconforming Expression in a Preadolescent Girl: A Case Report" }, { "source": "PMC", "id": "PMC13690424", "pmid": null, "doi": null, "title": "Fulminant Ischemic Colitis With Toxic Megacolon in a Young Man Receiving Testosterone Replacement Therapy Despite Therapeutic Phlebotomy for Hereditary Hemochromatosis: A Case Report" }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " } ] }, { "topic": "epidemiology", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (prevalence OR incidence OR burden OR mortality) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 19, "ids": [ { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "MED", "id": "42932137", "pmid": "42932137", "doi": "10.1007/s12306-026-00988-z", "title": "Generalized anxiety disorder may lead to increased healthcare utilization following total hip arthroplasty." }, { "source": "MED", "id": "42928507", "pmid": "42928507", "doi": "10.1002/eat.70249", "title": "Disordered Eating Behaviors and Comorbid Binge-Eating Disorder in Female Patients With Generalized Anxiety Disorder, Major Depressive Disorder, and Panic Disorder: A Transdiagnostic Approach." }, { "source": "MED", "id": "42934491", "pmid": "42934491", "doi": "10.1177/00048674261496100", "title": "Time to face the music: Mental health measures are failing us." }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "MED", "id": "42946258", "pmid": "42946258", "doi": "10.1016/j.jaclp.2026.10.343", "title": "Depressive and Anxiety symptoms associated with ICU admission in hypertensive disorders of pregnancy: a prospective cohort study." }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " }, { "source": "MED", "id": "42952997", "pmid": "42952997", "doi": "10.1098/rsos.252073", "title": "No association between body dissatisfaction and attentional bias towards lower-weight bodies in a non-clinical sample of women: an eye-tracking study. " }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "PMC", "id": "PMC13716809", "pmid": null, "doi": null, "title": "Perceived neijuan profiles and problematic short-form video use among Chinese college students: indirect associations through anxiety and escape motivation" }, { "source": "PMC", "id": "PMC13717537", "pmid": null, "doi": null, "title": "Attention-Deficit/Hyperactivity Disorder With Family Relational Challenges and Persistent Gender-Nonconforming Expression in a Preadolescent Girl: A Case Report" }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" } ] }, { "topic": "mechanism", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (worry OR neuroimaging OR genetic*) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 11, "ids": [ { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "PMC", "id": "PMC13716809", "pmid": null, "doi": null, "title": "Perceived neijuan profiles and problematic short-form video use among Chinese college students: indirect associations through anxiety and escape motivation" }, { "source": "PMC", "id": "PMC13717537", "pmid": null, "doi": null, "title": "Attention-Deficit/Hyperactivity Disorder With Family Relational Challenges and Persistent Gender-Nonconforming Expression in a Preadolescent Girl: A Case Report" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " } ] }, { "topic": "screening", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (GAD-7 OR GAD-2 OR HAM-A OR screening) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 20, "ids": [ { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "PPR", "id": "PPR1349741", "pmid": null, "doi": "10.12688/wellcomeopenres.26228.1", "title": "Tele-Adaptation and Feasibility of a Brief Yoga Therapy Module for Generalized Anxiety Disorder: A Pilot Study" }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "MED", "id": "42932137", "pmid": "42932137", "doi": "10.1007/s12306-026-00988-z", "title": "Generalized anxiety disorder may lead to increased healthcare utilization following total hip arthroplasty." }, { "source": "PPR", "id": "PPR1349433", "pmid": null, "doi": "10.64898/2026.10.21.26366048", "title": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis" }, { "source": "MED", "id": "42952997", "pmid": "42952997", "doi": "10.1098/rsos.252073", "title": "No association between body dissatisfaction and attentional bias towards lower-weight bodies in a non-clinical sample of women: an eye-tracking study. " }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "MED", "id": "42946258", "pmid": "42946258", "doi": "10.1016/j.jaclp.2026.10.343", "title": "Depressive and Anxiety symptoms associated with ICU admission in hypertensive disorders of pregnancy: a prospective cohort study." }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "PPR", "id": "PPR1353779", "pmid": null, "doi": "10.21203/rs.3.rs-10985453/v1", "title": "Identification of shared blood transcriptomic features and candidate sedative targets in chronic insomnia with comorbid anxiety: an in-silico study" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " }, { "source": "PMC", "id": "PMC13716809", "pmid": null, "doi": null, "title": "Perceived neijuan profiles and problematic short-form video use among Chinese college students: indirect associations through anxiety and escape motivation" }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." } ] }, { "topic": "cbt", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (CBT OR \"cognitive behav*\") AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 1, "ids": [ { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" } ] }, { "topic": "other-psych", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (metacognitive OR mindfulness OR ACT) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 6, "ids": [ { "source": "PPR", "id": "PPR1349433", "pmid": null, "doi": "10.64898/2026.10.21.26366048", "title": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis" }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." } ] }, { "topic": "ssri", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (SSRI OR SNRI OR antidepressant*) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 2, "ids": [ { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" } ] }, { "topic": "other-drugs", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (pregabalin OR benzodiazepine* OR cannabidiol) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 1, "ids": [ { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " } ] }, { "topic": "digital", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (internet OR iCBT OR digital OR app) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 7, "ids": [ { "source": "MED", "id": "42944768", "pmid": "42944768", "doi": "10.1556/2006.2026.00120", "title": "Gaming-related harms and help-seeking experiences across problem gaming risk groups: A cluster profile analysis." }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "PMC", "id": "PMC13716809", "pmid": null, "doi": null, "title": "Perceived neijuan profiles and problematic short-form video use among Chinese college students: indirect associations through anxiety and escape motivation" }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" } ] }, { "topic": "resistant", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (treatment-resistant OR rTMS OR psychedelic OR ulotaront) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 2, "ids": [ { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" } ] }, { "topic": "course", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (relapse OR remission OR course) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 8, "ids": [ { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "PMC", "id": "PMC13717537", "pmid": null, "doi": null, "title": "Attention-Deficit/Hyperactivity Disorder With Family Relational Challenges and Persistent Gender-Nonconforming Expression in a Preadolescent Girl: A Case Report" }, { "source": "PMC", "id": "PMC13690424", "pmid": null, "doi": null, "title": "Fulminant Ischemic Colitis With Toxic Megacolon in a Young Man Receiving Testosterone Replacement Therapy Despite Therapeutic Phlebotomy for Hereditary Hemochromatosis: A Case Report" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" } ] }, { "topic": "populations", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (child* OR perinatal OR geriatric OR veteran*) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 8, "ids": [ { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13717537", "pmid": null, "doi": null, "title": "Attention-Deficit/Hyperactivity Disorder With Family Relational Challenges and Persistent Gender-Nonconforming Expression in a Preadolescent Girl: A Case Report" }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " } ] }, { "topic": "comorbidity", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (comorbid* OR depression OR \"primary care\") AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 22, "ids": [ { "source": "MED", "id": "42928507", "pmid": "42928507", "doi": "10.1002/eat.70249", "title": "Disordered Eating Behaviors and Comorbid Binge-Eating Disorder in Female Patients With Generalized Anxiety Disorder, Major Depressive Disorder, and Panic Disorder: A Transdiagnostic Approach." }, { "source": "MED", "id": "42937060", "pmid": "42937060", "doi": "10.1097/yco.0000000000001132", "title": "Anxiety and suicide risk: mechanism, timing, and clinical utility." }, { "source": "MED", "id": "42934491", "pmid": "42934491", "doi": "10.1177/00048674261496100", "title": "Time to face the music: Mental health measures are failing us." }, { "source": "MED", "id": "42932137", "pmid": "42932137", "doi": "10.1007/s12306-026-00988-z", "title": "Generalized anxiety disorder may lead to increased healthcare utilization following total hip arthroplasty." }, { "source": "PPR", "id": "PPR1349741", "pmid": null, "doi": "10.12688/wellcomeopenres.26228.1", "title": "Tele-Adaptation and Feasibility of a Brief Yoga Therapy Module for Generalized Anxiety Disorder: A Pilot Study" }, { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "MED", "id": "42946258", "pmid": "42946258", "doi": "10.1016/j.jaclp.2026.10.343", "title": "Depressive and Anxiety symptoms associated with ICU admission in hypertensive disorders of pregnancy: a prospective cohort study." }, { "source": "PPR", "id": "PPR1353779", "pmid": null, "doi": "10.21203/rs.3.rs-10985453/v1", "title": "Identification of shared blood transcriptomic features and candidate sedative targets in chronic insomnia with comorbid anxiety: an in-silico study" }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "MED", "id": "42952997", "pmid": "42952997", "doi": "10.1098/rsos.252073", "title": "No association between body dissatisfaction and attentional bias towards lower-weight bodies in a non-clinical sample of women: an eye-tracking study. " }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "MED", "id": "42953780", "pmid": "42953780", "doi": "10.2147/ndt.s624721", "title": "Neuropsychological and Event-Related Potential Abnormalities Three Months After Brainstem Lacunar Infarction: An Exploratory Case-Control Study. " }, { "source": "PMC", "id": "PMC13690424", "pmid": null, "doi": null, "title": "Fulminant Ischemic Colitis With Toxic Megacolon in a Young Man Receiving Testosterone Replacement Therapy Despite Therapeutic Phlebotomy for Hereditary Hemochromatosis: A Case Report" }, { "source": "PMC", "id": "PMC13690722", "pmid": null, "doi": null, "title": "Measuring state and trait anxiety in Turkish adolescents: development and validation of the six-item short forms of the state–trait anxiety inventory" }, { "source": "PMC", "id": "PMC13716606", "pmid": null, "doi": null, "title": "Association between uncertainty regarding malignant risk and anxiety in patients with pulmonary nodules: a serial mediation analysis of illness perception and rumination" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13690931", "pmid": null, "doi": null, "title": "Narcissistic traits and emotional dependence on large language models among adolescents" } ] }, { "topic": "guidelines", "query": "(\"generalized anxiety disorder\" OR \"generalised anxiety disorder\") AND (guideline* OR safety OR qualitative) AND FIRST_PDATE:[2026-10-24 TO 2026-10-31]", "hitCount": 12, "ids": [ { "source": "PPR", "id": "PPR1349433", "pmid": null, "doi": "10.64898/2026.10.21.26366048", "title": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis" }, { "source": "PMC", "id": "PMC13716643", "pmid": null, "doi": null, "title": "Anxiety in patients with lower-extremity deep vein thrombosis: a patient-centred sequential explanatory mixed-methods study of prevalence, associated factors, and patient experiences" }, { "source": "MED", "id": "42934775", "pmid": "42934775", "doi": "10.1186/s43019-026-00353-1", "title": "Smartphone-derived mobility metrics identify distinct recovery phenotypes following ACL reconstruction: associations with function, pain, and psychological health." }, { "source": "MED", "id": "42933832", "pmid": "42933832", "doi": "10.1136/bmjopen-2026-117088", "title": "Exploring the nature, development and effects of complex emotions in Sheffield and Plymouth, UK: a longitudinal mixed methods study protocol." }, { "source": "PMC", "id": "PMC13717602", "pmid": null, "doi": null, "title": "Research progress on intervention strategies for post‐traumatic stress in military personnel exposed to cold environments and radiological threats" }, { "source": "MED", "id": "42952997", "pmid": "42952997", "doi": "10.1098/rsos.252073", "title": "No association between body dissatisfaction and attentional bias towards lower-weight bodies in a non-clinical sample of women: an eye-tracking study. " }, { "source": "PMC", "id": "PMC13717630", "pmid": null, "doi": null, "title": "Cross-sectional assessment of anxiety and insomnia of Spanish veterinarians following African swine fever wild boar detection in Spain" }, { "source": "PMC", "id": "PMC13690714", "pmid": null, "doi": null, "title": "Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder" }, { "source": "MED", "id": "42953409", "pmid": "42953409", "doi": "10.2147/ndt.s633019", "title": "Evaluation of the Efficacy and Safety of Ashwagandha Caplet in Patients Suffering from Mild to Moderate Stress and Anxiety Disorders: A Multicentric, Double-Blind, Randomized, Placebo-Controlled, Clinical Trial. " }, { "source": "PMC", "id": "PMC13716581", "pmid": null, "doi": null, "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis" }, { "source": "PMC", "id": "PMC13717318", "pmid": null, "doi": null, "title": "Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?" }, { "source": "PMC", "id": "PMC13690424", "pmid": null, "doi": null, "title": "Fulminant Ischemic Colitis With Toxic Megacolon in a Young Man Receiving Testosterone Replacement Therapy Despite Therapeutic Phlebotomy for Hereditary Hemochromatosis: A Case Report" } ] } ], "clinicaltrials_gov": { "individual_records": { "NCT00052078": { "overallStatus": "COMPLETED", "enrollmentCount": 488, "hasResults": true, "lastUpdatePostDate": "2017-09-19", "resultsFirstPostDate": "2017-04-25", "briefTitle": "Child and Adolescent Anxiety Disorders (CAMS)" }, "NCT00426426": { "overallStatus": "COMPLETED", "enrollmentCount": 68, "hasResults": false, "lastUpdatePostDate": "2018-10-11", "resultsFirstPostDate": null, "briefTitle": "Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GAD" }, "NCT01629966": { "overallStatus": "COMPLETED", "enrollmentCount": 680, "hasResults": true, "lastUpdatePostDate": "2019-12-18", "resultsFirstPostDate": "2019-12-18", "briefTitle": "Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety Disorder" }, "NCT01766401": { "overallStatus": "COMPLETED", "enrollmentCount": 402, "hasResults": true, "lastUpdatePostDate": "2019-12-18", "resultsFirstPostDate": "2019-12-18", "briefTitle": "Safety, Efficacy and Tolerability of Vilazodone in Patients With Generalized Anxiety Disorder" }, "NCT01785108": { "overallStatus": "COMPLETED", "enrollmentCount": 60, "hasResults": false, "lastUpdatePostDate": "2017-08-23", "resultsFirstPostDate": null, "briefTitle": "DIABGAD - Trial to Preserve Insulin Secretion in Type 1 Diabetes Using GAD-Alum (Diamyd) in Combination With Vitamin D and Ibuprofen" }, "NCT01844115": { "overallStatus": "COMPLETED", "enrollmentCount": 415, "hasResults": true, "lastUpdatePostDate": "2019-12-18", "resultsFirstPostDate": "2019-12-18", "briefTitle": "Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety Disorder" }, "NCT02305797": { "overallStatus": "COMPLETED", "enrollmentCount": 495, "hasResults": true, "lastUpdatePostDate": "2018-09-26", "resultsFirstPostDate": "2018-09-26", "briefTitle": "EDG004 Treatment of Adult Patients With Generalized Anxiety Disorder (GAD)" }, "NCT02818751": { "overallStatus": "COMPLETED", "enrollmentCount": 84, "hasResults": false, "lastUpdatePostDate": "2020-11-06", "resultsFirstPostDate": null, "briefTitle": "Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety" }, "NCT03522844": { "overallStatus": "COMPLETED", "enrollmentCount": 276, "hasResults": false, "lastUpdatePostDate": "2022-01-11", "resultsFirstPostDate": null, "briefTitle": "Treatments for Anxiety: Meditation and Escitalopram" }, "NCT03829241": { "overallStatus": "COMPLETED", "enrollmentCount": 881, "hasResults": true, "lastUpdatePostDate": "2024-05-08", "resultsFirstPostDate": "2022-12-28", "briefTitle": "Randomized Trial of Adult Participants With Generalized Anxiety Disorder" }, "NCT03924323": { "overallStatus": "COMPLETED", "enrollmentCount": 273, "hasResults": true, "lastUpdatePostDate": "2022-11-14", "resultsFirstPostDate": "2022-11-14", "briefTitle": "A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder" }, "NCT04221997": { "overallStatus": "RECRUITING", "enrollmentCount": 150, "hasResults": false, "lastUpdatePostDate": "2024-11-01", "resultsFirstPostDate": null, "briefTitle": "Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders." }, "NCT04557891": { "overallStatus": "RECRUITING", "enrollmentCount": 48, "hasResults": false, "lastUpdatePostDate": "2026-02-10", "resultsFirstPostDate": null, "briefTitle": "Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)" }, "NCT04895995": { "overallStatus": "COMPLETED", "enrollmentCount": 30, "hasResults": false, "lastUpdatePostDate": "2026-09-02", "resultsFirstPostDate": null, "briefTitle": "Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population" }, "NCT05351879": { "overallStatus": "COMPLETED", "enrollmentCount": 6, "hasResults": false, "lastUpdatePostDate": "2023-12-11", "resultsFirstPostDate": null, "briefTitle": "Evaluation of a Booster Administration of GAD-alum (Diamyd®) in Individuals With Type 1 Diabetes" }, "NCT05407064": { "overallStatus": "COMPLETED", "enrollmentCount": 198, "hasResults": true, "lastUpdatePostDate": "2026-02-27", "resultsFirstPostDate": "2025-03-20", "briefTitle": "A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms" }, "NCT05427708": { "overallStatus": "RECRUITING", "enrollmentCount": 180, "hasResults": false, "lastUpdatePostDate": "2025-08-24", "resultsFirstPostDate": null, "briefTitle": "Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety" }, "NCT05729373": { "overallStatus": "COMPLETED", "enrollmentCount": 434, "hasResults": false, "lastUpdatePostDate": "2025-10-10", "resultsFirstPostDate": null, "briefTitle": "A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder" }, "NCT05749055": { "overallStatus": "COMPLETED", "enrollmentCount": 252, "hasResults": false, "lastUpdatePostDate": "2026-09-21", "resultsFirstPostDate": null, "briefTitle": "ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder" }, "NCT05772104": { "overallStatus": "RECRUITING", "enrollmentCount": 495, "hasResults": false, "lastUpdatePostDate": "2024-12-18", "resultsFirstPostDate": null, "briefTitle": "Clinical Trial of Shugan Jieyu Capsule in Generalized Anxiety Disorder" }, "NCT05970510": { "overallStatus": "COMPLETED", "enrollmentCount": 555, "hasResults": false, "lastUpdatePostDate": "2026-07-08", "resultsFirstPostDate": null, "briefTitle": "A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Generalized Anxiety Disorder." }, "NCT06051721": { "overallStatus": "COMPLETED", "enrollmentCount": 36, "hasResults": false, "lastUpdatePostDate": "2026-08-13", "resultsFirstPostDate": null, "briefTitle": "A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)" }, "NCT06243640": { "overallStatus": "RECRUITING", "enrollmentCount": 504, "hasResults": false, "lastUpdatePostDate": "2024-02-06", "resultsFirstPostDate": null, "briefTitle": "Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GAD" }, "NCT06278909": { "overallStatus": "RECRUITING", "enrollmentCount": 10, "hasResults": false, "lastUpdatePostDate": "2025-04-08", "resultsFirstPostDate": null, "briefTitle": "Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility Study" }, "NCT06480383": { "overallStatus": "RECRUITING", "enrollmentCount": 705, "hasResults": false, "lastUpdatePostDate": "2026-09-25", "resultsFirstPostDate": null, "briefTitle": "Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder" }, "NCT06653296": { "overallStatus": "COMPLETED", "enrollmentCount": 38, "hasResults": false, "lastUpdatePostDate": "2025-09-17", "resultsFirstPostDate": null, "briefTitle": "A Dose-Response Safety Study of ENX-102 in Patients With GAD" }, "NCT06701903": { "overallStatus": "RECRUITING", "enrollmentCount": 570, "hasResults": false, "lastUpdatePostDate": "2026-09-25", "resultsFirstPostDate": null, "briefTitle": "Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder" }, "NCT06741228": { "overallStatus": "ACTIVE_NOT_RECRUITING", "enrollmentCount": 214, "hasResults": false, "lastUpdatePostDate": "2026-09-25", "resultsFirstPostDate": null, "briefTitle": "A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)" }, "NCT06809595": { "overallStatus": "ACTIVE_NOT_RECRUITING", "enrollmentCount": 245, "hasResults": false, "lastUpdatePostDate": "2026-09-04", "resultsFirstPostDate": null, "briefTitle": "A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)" }, "NCT06811311": { "overallStatus": "RECRUITING", "enrollmentCount": 60, "hasResults": false, "lastUpdatePostDate": "2025-02-20", "resultsFirstPostDate": null, "briefTitle": "EEG Study on Neurophysiological and Psychological Effects of Ericksonian Hypnotherapy in Generalized Anxiety Disorder" }, "NCT06846320": { "overallStatus": "RECRUITING", "enrollmentCount": 315, "hasResults": false, "lastUpdatePostDate": "2026-06-17", "resultsFirstPostDate": null, "briefTitle": "Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder" }, "NCT06934525": { "overallStatus": "RECRUITING", "enrollmentCount": 501, "hasResults": false, "lastUpdatePostDate": "2026-07-31", "resultsFirstPostDate": null, "briefTitle": "Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings." }, "NCT06942429": { "overallStatus": "RECRUITING", "enrollmentCount": 556, "hasResults": false, "lastUpdatePostDate": "2026-02-27", "resultsFirstPostDate": null, "briefTitle": "Stepped Versus Stratified Care for Anxiety Disorders in Youth" }, "NCT06969170": { "overallStatus": "RECRUITING", "enrollmentCount": 50, "hasResults": false, "lastUpdatePostDate": "2026-08-12", "resultsFirstPostDate": null, "briefTitle": "Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder" }, "NCT07121712": { "overallStatus": "RECRUITING", "enrollmentCount": 40, "hasResults": false, "lastUpdatePostDate": "2025-09-10", "resultsFirstPostDate": null, "briefTitle": "Navigated cTBS for the Treatment of Generalized Anxiety Disorder" }, "NCT07123467": { "overallStatus": "RECRUITING", "enrollmentCount": 90, "hasResults": false, "lastUpdatePostDate": "2026-10-21", "resultsFirstPostDate": null, "briefTitle": "Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder" }, "NCT07201844": { "overallStatus": "RECRUITING", "enrollmentCount": 440, "hasResults": false, "lastUpdatePostDate": "2025-10-01", "resultsFirstPostDate": null, "briefTitle": "The Effect of Patient Preference for Treatment Model in Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder" }, "NCT07233278": { "overallStatus": "RECRUITING", "enrollmentCount": 48, "hasResults": false, "lastUpdatePostDate": "2026-08-28", "resultsFirstPostDate": null, "briefTitle": "High-Intensity, Low-Frequency Periodic rTMS Over the Right Dorsolateral Prefrontal Cortex on Cardiac Autonomic Regulation in Women With Recurrent Pregnancy Loss and Anxiety" }, "NCT07391020": { "overallStatus": "ACTIVE_NOT_RECRUITING", "enrollmentCount": 300, "hasResults": false, "lastUpdatePostDate": "2026-09-28", "resultsFirstPostDate": null, "briefTitle": "Text Message Safety Behavior Fading for Pathological Worry" }, "NCT07759128": { "overallStatus": "RECRUITING", "enrollmentCount": 576, "hasResults": false, "lastUpdatePostDate": "2026-10-26", "resultsFirstPostDate": null, "briefTitle": "A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder" }, "NCT07767903": { "overallStatus": "RECRUITING", "enrollmentCount": 384, "hasResults": false, "lastUpdatePostDate": "2026-10-20", "resultsFirstPostDate": null, "briefTitle": "A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder" }, "NCT07786454": { "overallStatus": "RECRUITING", "enrollmentCount": 1120, "hasResults": false, "lastUpdatePostDate": "2026-10-20", "resultsFirstPostDate": null, "briefTitle": "A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder" }, "NCT07807865": { "overallStatus": "RECRUITING", "enrollmentCount": 900, "hasResults": false, "lastUpdatePostDate": "2026-09-29", "resultsFirstPostDate": null, "briefTitle": "A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)" }, "NCT07856420": { "overallStatus": "NOT_YET_RECRUITING", "enrollmentCount": 705, "hasResults": false, "lastUpdatePostDate": "2026-10-02", "resultsFirstPostDate": null, "briefTitle": "A Study of JNJ-99245354 (ITI-1284) as an Adjunctive Treatment in Participants With Generalized Anxiety Disorder (GAD) Who Have an Inadequate Response to GAD Treatment" }, "NCT07866794": { "overallStatus": "NOT_YET_RECRUITING", "enrollmentCount": 135, "hasResults": false, "lastUpdatePostDate": "2026-10-08", "resultsFirstPostDate": null, "briefTitle": "Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty Versus Applied Relaxation" }, "NCT07873905": { "overallStatus": "COMPLETED", "enrollmentCount": 110, "hasResults": false, "lastUpdatePostDate": "2026-10-14", "resultsFirstPostDate": null, "briefTitle": "Digital Single-Session Cognitive Behavioural Therapy in Healthy Adults" }, "NCT07876453": { "overallStatus": "COMPLETED", "enrollmentCount": 21, "hasResults": false, "lastUpdatePostDate": "2026-10-21", "resultsFirstPostDate": null, "briefTitle": "Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and Anxiety" } }, "window": { "first-posted": { "totalCount": null, "studies": [ { "nctId": "NCT07899424", "briefTitle": "Microbiota Modulation for Psychiatry Patients", "overallStatus": "NOT_YET_RECRUITING", "lastUpdatePostDate": "2026-10-27", "studyFirstPostDate": "2026-10-27", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 62, "phases": [ "PHASE1" ], "conditions": [ "Depression - Major Depressive Disorder", "Generalized Anxiety Disorder (GAD)", "Anxiety" ] }, { "nctId": "NCT07906522", "briefTitle": "Future School of Comprehensive Well-Being", "overallStatus": "ACTIVE_NOT_RECRUITING", "lastUpdatePostDate": "2026-10-30", "studyFirstPostDate": "2026-10-30", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 1440, "phases": [ "NA" ], "conditions": [ "Learning", "Comprehensive Wellbeing", "Social Wellbeing", "Physical Wellbeing", "Mental Wellbeing", "Pedagogical Practices", "General Mental Health and Well-Being", "Mental Disorders", "Common Mental Disorders (CMD)", "Sedentary Behavior", "Physical Inactivity", "Depressive Symptom", "Anxiety", "Resilience, Psychological" ] }, { "nctId": "NCT07902765", "briefTitle": "Music for Reducing Anxiety Before Surgery", "overallStatus": "NOT_YET_RECRUITING", "lastUpdatePostDate": "2026-10-29", "studyFirstPostDate": "2026-10-29", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 92, "phases": [ "NA" ], "conditions": [ "Preoperative Anxiety" ] } ] }, "last-updated": { "totalCount": null, "studies": [ { "nctId": "NCT01793168", "briefTitle": "Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford", "overallStatus": "RECRUITING", "lastUpdatePostDate": "2026-10-28", "studyFirstPostDate": "2013-02-15", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 20000, "phases": null, "conditions": [ "Rare Disorders", "Undiagnosed Disorders", "Disorders of Unknown Prevalence", "Cornelia De Lange Syndrome", "Prenatal Benign Hypophosphatasia", "Perinatal Lethal Hypophosphatasia", "Odontohypophosphatasia", "Adult Hypophosphatasia", "Childhood-onset Hypophosphatasia", "Infantile Hypophosphatasia", "Hypophosphatasia", "Kabuki Syndrome", "Bohring-Opitz Syndrome", "Narcolepsy Without Cataplexy", "Narcolepsy-cataplexy", "Hypersomnolence Disorder", "Idiopathic Hypersomnia Without Long Sleep Time", "Idiopathic Hypersomnia With Long Sleep Time", "Idiopathic Hypersomnia", "Kleine-Levin Syndrome", "Kawasaki Disease", "Leiomyosarcoma", "Leiomyosarcoma of the Corpus Uteri", "Leiomyosarcoma of the Cervix Uteri", "Leiomyosarcoma of Small Intestine", "Acquired Myasthenia Gravis", "Addison Disease", "Hyperacusis (Hyperacousis)", "Juvenile Myasthenia Gravis", "Transient Neonatal Myasthenia Gravis", "Williams Syndrome", "Lyme Disease", "Myasthenia Gravis", "Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome)", "Isolated Klippel-Feil Syndrome", "Frasier Syndrome", "Denys-Drash Syndrome", "Beckwith-Wiedemann Syndrome", "Emanuel Syndrome", "Isolated Aniridia", "Axenfeld-Rieger Syndrome", "Aniridia-intellectual Disability Syndrome", "Aniridia - Renal Agenesis - Psychomotor Retardation", "Aniridia - Ptosis - Intellectual Disability - Familial Obesity", "Aniridia - Cerebellar Ataxia - Intellectual Disability", "Aniridia - Absent Patella", "Aniridia", "Peters Anomaly - Cataract", "Peters Anomaly", "Potocki-Shaffer Syndrome", "Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11", "Silver-Russell Syndrome Due to Imprinting Defect of 11p15", "Silver-Russell Syndrome Due to 11p15 Microduplication", "Syndromic Aniridia", "WAGR Syndrome", "Wolf-Hirschhorn Syndrome", "4p16.3 Microduplication Syndrome", "4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome", "Autosomal Recessive Stickler Syndrome", "Stickler Syndrome Type 2", "Stickler Syndrome Type 1", "Stickler Syndrome", "Mucolipidosis Type 4", "X-linked Spinocerebellar Ataxia Type 4", "X-linked Spinocerebellar Ataxia Type 3", "X-linked Intellectual Disability - Ataxia - Apraxia", "X-linked Progressive Cerebellar Ataxia", "X-linked Non Progressive Cerebellar Ataxia", "X-linked Cerebellar Ataxia", "Vitamin B12 Deficiency Ataxia", "Toxic Exposure Ataxia", "Unclassified Autosomal Dominant Spinocerebellar Ataxia", "Thyroid Antibody Ataxia", "Sporadic Adult-onset Ataxia of Unknown Etiology", "Spinocerebellar Ataxia With Oculomotor Anomaly", "Spinocerebellar Ataxia With Epilepsy", "Spinocerebellar Ataxia With Axonal Neuropathy Type 2", "Spinocerebellar Ataxia Type 8", "Spinocerebellar Ataxia Type 7", "Spinocerebellar Ataxia Type 6", "Spinocerebellar Ataxia Type 5", "Spinocerebellar Ataxia Type 4", "Spinocerebellar Ataxia Type 37", "Spinocerebellar Ataxia Type 36", "Spinocerebellar Ataxia Type 35", "Spinocerebellar Ataxia Type 34", "Spinocerebellar Ataxia Type 32", "Spinocerebellar Ataxia Type 31", "Spinocerebellar Ataxia Type 30", "Spinocerebellar Ataxia Type 3", "Spinocerebellar Ataxia Type 29", "Spinocerebellar Ataxia Type 28", "Spinocerebellar Ataxia Type 27", "Spinocerebellar Ataxia Type 26", "Spinocerebellar Ataxia Type 25", "Spinocerebellar Ataxia Type 23", "Spinocerebellar Ataxia Type 22", "Spinocerebellar Ataxia Type 21", "Spinocerebellar Ataxia Type 20", "Spinocerebellar Ataxia Type 2", "Spinocerebellar Ataxia Type 19/22", "Spinocerebellar Ataxia Type 18", "Spinocerebellar Ataxia Type 17", "Spinocerebellar Ataxia Type 16", "Spinocerebellar Ataxia Type 15/16", "Spinocerebellar Ataxia Type 14", "Spinocerebellar Ataxia Type 13", "Spinocerebellar Ataxia Type 12", "Spinocerebellar Ataxia Type 11", "Spinocerebellar Ataxia Type 10", "Spinocerebellar Ataxia Type 1 With Axonal Neuropathy", "Spinocerebellar Ataxia Type 1", "Spinocerebellar Ataxia - Unknown", "Spinocerebellar Ataxia - Dysmorphism", "Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature", "Spasticity-ataxia-gait Anomalies Syndrome", "Spastic Ataxia With Congenital Miosis", "Spastic Ataxia - Corneal Dystrophy", "Spastic Ataxia", "Rare Hereditary Ataxia", "Rare Ataxia", "Recessive Mitochondrial Ataxia Syndrome", "Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature", "Posterior Column Ataxia - Retinitis Pigmentosa", "Post-Stroke Ataxia", "Post-Head Injury Ataxia", "Post Vaccination Ataxia", "Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract", "Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus", "Non-hereditary Degenerative Ataxia", "Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity", "Olivopontocerebellar Atrophy - Deafness", "NARP Syndrome", "Myoclonus - Cerebellar Ataxia - Deafness", "Multiple System Atrophy, Parkinsonian Type", "Multiple System Atrophy, Cerebellar Type", "Multiple System Atrophy", "Maternally-inherited Leigh Syndrome", "Machado-Joseph Disease Type 3", "Machado-Joseph Disease Type 2", "Machado-Joseph Disease Type 1", "Leigh Syndrome", "Late-onset Ataxia With Dementia", "Infection or Post Infection Ataxia", "GAD Ataxia", "Hereditary Episodic Ataxia", "Gliadin/Gluten Ataxia", "Friedreich Ataxia", "Fragile X-associated Tremor/Ataxia Syndrome", "Familial Paroxysmal Ataxia", "Exposure to Medications Ataxia", "Episodic Ataxia With Slurred Speech", "Episodic Ataxia Unknown Type", "Episodic Ataxia Type 7", "Episodic Ataxia Type 6", "Episodic Ataxia Type 5", "Episodic Ataxia Type 4", "Episodic Ataxia Type 3", "Episodic Ataxia Type 1", "Epilepsy and/or Ataxia With Myoclonus as Major Feature", "Early-onset Spastic Ataxia-neuropathy Syndrome", "Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity", "Early-onset Cerebellar Ataxia With Retained Tendon Reflexes", "Early-onset Ataxia With Dementia", "Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia", "Dilated Cardiomyopathy With Ataxia", "Cataract - Ataxia - Deafness", "Cerebellar Ataxia, Cayman Type", "Cerebellar Ataxia With Peripheral Neuropathy", "Cerebellar Ataxia - Hypogonadism", "Cerebellar Ataxia - Ectodermal Dysplasia", "Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss", "Brain Tumor Ataxia", "Brachydactyly - Nystagmus - Cerebellar Ataxia", "Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia", "Autosomal Recessive Syndromic Cerebellar Ataxia", "Autosomal Recessive Spastic Ataxia With Leukoencephalopathy", "Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay", "Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria", "Autosomal Recessive Spastic Ataxia", "Autosomal Recessive Metabolic Cerebellar Ataxia", "Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine", "Autosomal Recessive Ataxia, Beauce Type", "Autosomal Recessive Ataxia Due to Ubiquinone Deficiency", "Autosomal Recessive Ataxia Due to PEX10 Deficiency", "Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia", "Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency", "Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency", "Autosomal Recessive Congenital Cerebellar Ataxia", "Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome", "Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity", "Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency", "Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect", "Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion", "Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation", "Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness", "Autosomal Recessive Cerebellar Ataxia", "Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly", "Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation", "Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy", "Autosomal Dominant Spastic Ataxia Type 1", "Autosomal Dominant Spastic Ataxia", "Autosomal Dominant Optic Atrophy", "Ataxia-telangiectasia Variant", "Ataxia-telangiectasia", "Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy", "Autosomal Dominant Cerebellar Ataxia Type 4", "Autosomal Dominant Cerebellar Ataxia Type 3", "Autosomal Dominant Cerebellar Ataxia Type 2", "Autosomal Dominant Cerebellar Ataxia Type 1", "Autosomal Dominant Cerebellar Ataxia", "Ataxia-telangiectasia-like Disorder", "Ataxia With Vitamin E Deficiency", "Ataxia With Dementia", "Ataxia - Oculomotor Apraxia Type 1", "Ataxia - Other", "Ataxia - Genetic Diagnosis - Unknown", "Acquired Ataxia", "Adult-onset Autosomal Recessive Cerebellar Ataxia", "Alcohol Related Ataxia", "Multiple Endocrine Neoplasia", "Multiple Endocrine Neoplasia Type II", "Multiple Endocrine Neoplasia Type 1", "Multiple Endocrine Neoplasia Type 2", "Multiple Endocrine Neoplasia, Type IV", "Multiple Endocrine Neoplasia, Type 3", "Multiple Endocrine Neoplasia (MEN) Syndrome", "Multiple Endocrine Neoplasia Type 2B", "Multiple Endocrine Neoplasia Type 2A", "Atypical Hemolytic Uremic Syndrome", "Atypical HUS", "Wiedemann-Steiner Syndrome", "Breast Implant-Associated Anaplastic Large Cell Lymphoma", "Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)", "Hemophagocytic Lymphohistiocytosis", "Behcet's Disease", "Alagille Syndrome", "Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD)", "Lowe Syndrome", "Pitt Hopkins Syndrome", "1p36 Deletion Syndrome", "Jansen Type Metaphyseal Chondrodysplasia", "Cockayne Syndrome", "Chronic Recurrent Multifocal Osteomyelitis", "CRMO", "Malan Syndrome", "Hereditary Sensory and Autonomic Neuropathy Type Ie", "VCP Disease", "Hypnic Jerking", "Sleep Myoclonus", "Mollaret Meningitis", "Recurrent Viral Meningitis", "CRB1", "Leber Congenital Amaurosis", "Retinitis Pigmentosa", "Rare Retinal Disorder", "KCNMA1-Channelopathy", "Primary Biliary Cirrhosis", "ZMYND11", "Transient Global Amnesia", "Glycogen Storage Disease", "Alstrom Syndrome", "White Sutton Syndrome", "DNM1", "EIEE31", "Myhre Syndrome", "Recurrent Respiratory Papillomatosis", "Laryngeal Papillomatosis", "Tracheal Papillomatosis", "Refsum Disease", "Nicolaides Baraitser Syndrome", "Leukodystrophy", "Tango2", "Cauda Equina Syndrome", "Rare Gastrointestinal Disorders", "Achalasia-Addisonian Syndrome", "Achalasia Cardia", "Achalasia Icrocephaly Syndrome", "Anal Fistula", "Congenital Sucrase-Isomaltase Deficiency", "Eosinophilic Gastroenteritis", "Idiopathic Gastroparesis", "Hirschsprung Disease", "Rare Inflammatory Bowel Disease", "Intestinal Pseudo-Obstruction", "Scleroderma", "Short Bowel Syndrome", "Sacral Agenesis", "Sacral Agenesis Syndrome", "Caudal Regression", "Scheuermann Disease", "SMC1A Truncated Mutations (Causing Loss of Gene Function)", "Cystinosis", "Juvenile Nephropathic Cystinosis", "Nephropathic Cystinosis", "Kennedy Disease", "Spinal Bulbar Muscular Atrophy", "Warburg Micro Syndrome", "Mucolipidoses", "Mitochondrial Diseases", "Mitochondrial Aminoacyl-tRNA Synthetases", "Mt-aaRS Disorders", "Hypertrophic Olivary Degeneration", "Non-Ketotic Hyperglycinemia", "Fish Odor Syndrome", "Halitosis", "Isolated Congenital Asplenia", "Lambert Eaton (LEMS)", "Biliary Atresia", "STAG1 Gene Mutation", "Coffin Lowry Syndrome", "Borjeson-Forssman-Lehman Syndrome", "Blau Syndrome", "Arginase 1 Deficiency", "HSPB8 Myopathy", "Beta-Mannosidosis", "TBX4 Syndrome", "DHDDS Gene Mutations", "MAND-MBD5-Associated Neurodevelopmental Disorder", "Constitutional Mismatch Repair Deficiency (CMMRD)", "SPATA5 Disorder", "SPATA5L1 Related Disorder", "Acrodysostosis", "Multi-systematic Smooth Muscle Dysfunction Syndrome", "CRELD1 (Cysteine Rich With EGF Like Domains 1)", "GNB1 Syndrome", "Pyruvate Dehydrogenase Complex Deficiency Disease", "Beta Mannosidosis", "Kbg Syndrome", "Labrune Syndrome", "Metachromatic Leukodystrophy (MLD)", "Moyamoya Disease", "OPHN1 Syndrome", "Oculopharyngeal Muscular Dystrophy (OPMD)", "TUBB3 Mutation", "WOREE (WWOX-related Epileptic Encephalopathy", "SCAR12", "Skraban-Deardorff Syndrome", "Hereditary Myopathy With Early Respiratory Failure", "Parry Romberg Syndrome", "Lesch-Nyhan Disease", "GNB1 Gene Mutation", "Pierpont Syndrome", "TBL1XR1 Gene Variant", "Activated PI3K Delta Syndrome (APDS)", "Adult Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia (ALSP)", "Brain Abnormalities, Neurodegeneration, and Dysosteosclerosis", "CSF1R Related Disease (CSF1R-RD)", "Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids and Pigmented Glia", "Nasu-Hakola Disease" ] }, { "nctId": "NCT07821840", "briefTitle": "CannaRiver CBD Calm for Anxiety, Sleep, and Well-Being in Adults With Generalized Anxiety Disorder", "overallStatus": "NOT_YET_RECRUITING", "lastUpdatePostDate": "2026-10-29", "studyFirstPostDate": "2026-09-16", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 60, "phases": [ "NA" ], "conditions": [ "Generalized Anxiety Disorder" ] }, { "nctId": "NCT07899424", "briefTitle": "Microbiota Modulation for Psychiatry Patients", "overallStatus": "NOT_YET_RECRUITING", "lastUpdatePostDate": "2026-10-27", "studyFirstPostDate": "2026-10-27", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 62, "phases": [ "PHASE1" ], "conditions": [ "Depression - Major Depressive Disorder", "Generalized Anxiety Disorder (GAD)", "Anxiety" ] }, { "nctId": "NCT06198023", "briefTitle": "Targeting Social Function in Anxiety and Eating Disorders", "overallStatus": "ACTIVE_NOT_RECRUITING", "lastUpdatePostDate": "2026-10-30", "studyFirstPostDate": "2024-01-10", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 60, "phases": [ "NA" ], "conditions": [ "Eating Disorders", "Anorexia Nervosa", "Bulimia Nervosa", "Atypical Anorexia Nervosa", "Purging (Eating Disorders)", "Other Specified Feeding or Eating Disorder", "Social Anxiety Disorder", "Generalized Anxiety Disorder (GAD)" ] }, { "nctId": "NCT07759128", "briefTitle": "A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder", "overallStatus": "RECRUITING", "lastUpdatePostDate": "2026-10-26", "studyFirstPostDate": "2026-08-12", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 576, "phases": [ "PHASE3" ], "conditions": [ "Generalized Anxiety Disorder" ] }, { "nctId": "NCT07906522", "briefTitle": "Future School of Comprehensive Well-Being", "overallStatus": "ACTIVE_NOT_RECRUITING", "lastUpdatePostDate": "2026-10-30", "studyFirstPostDate": "2026-10-30", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 1440, "phases": [ "NA" ], "conditions": [ "Learning", "Comprehensive Wellbeing", "Social Wellbeing", "Physical Wellbeing", "Mental Wellbeing", "Pedagogical Practices", "General Mental Health and Well-Being", "Mental Disorders", "Common Mental Disorders (CMD)", "Sedentary Behavior", "Physical Inactivity", "Depressive Symptom", "Anxiety", "Resilience, Psychological" ] }, { "nctId": "NCT07392645", "briefTitle": "Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms", "overallStatus": "RECRUITING", "lastUpdatePostDate": "2026-10-26", "studyFirstPostDate": "2026-02-06", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 123, "phases": [ "NA" ], "conditions": [ "Generalized Anxiety Disorder" ] }, { "nctId": "NCT07902765", "briefTitle": "Music for Reducing Anxiety Before Surgery", "overallStatus": "NOT_YET_RECRUITING", "lastUpdatePostDate": "2026-10-29", "studyFirstPostDate": "2026-10-29", "resultsFirstPostDate": null, "hasResults": false, "enrollmentCount": 92, "phases": [ "NA" ], "conditions": [ "Preoperative Anxiety" ] } ] }, "results-posted": { "totalCount": null, "studies": [] } } }, "nct_pubmed_searches": { "NCT03829241": { "count": "0", "idlist": [], "translation": "NCT03829241" }, "NCT05749055": { "count": "0", "idlist": [], "translation": "NCT05749055" }, "NCT05729373": { "count": "0", "idlist": [], "translation": "NCT05729373" }, "NCT02305797": { "count": "0", "idlist": [], "translation": "NCT02305797" }, "NCT07759128": { "count": "0", "idlist": [], "translation": "NCT07759128" }, "NCT07767903": { "count": "0", "idlist": [], "translation": "NCT07767903" }, "NCT07786454": { "count": "0", "idlist": [], "translation": "NCT07786454" }, "NCT07807865": { "count": "0", "idlist": [], "translation": "NCT07807865" }, "NCT07856420": { "count": "0", "idlist": [], "translation": "NCT07856420" }, "NCT07866794": { "count": "0", "idlist": [], "translation": "NCT07866794" }, "NCT07123467": { "count": "0", "idlist": [], "translation": "NCT07123467" }, "NCT06809595": { "count": "1", "idlist": [ "41730563" ], "translation": "\"NCT06809595\"[All Fields]" }, "NCT06741228": { "count": "2", "idlist": [ "41730563", "40032306" ], "translation": "\"NCT06741228\"[All Fields]" }, "ISRCTN16993990": { "count": "0", "idlist": [], "translation": "ISRCTN16993990" }, "PETRA pregabalin GAD": { "count": "1", "idlist": [ "42717383" ], "translation": "(\"int conf pervasive technol relat assist environ\"[Journal] OR \"petra\"[All Fields]) AND (\"pregabalin\"[Supplementary Concept] OR \"pregabalin\"[All Fields] OR \"pregabalin\"[MeSH Terms] OR \"pregabaline\"[All Fields] OR \"pregabalin s\"[All Fields]) AND \"GAD\"[All Fields]" }, "ENX-102 GAD": { "count": "0", "idlist": [], "translation": "\"ENX-102\"[All Fields] AND \"GAD\"[All Fields]" }, "ulotaront GAD OR SEP-363856 GAD": { "count": "2", "idlist": [ "41117250", "39002806" ], "translation": "((\"sep 363856\"[Supplementary Concept] OR \"sep 363856\"[All Fields] OR \"ulotaront\"[All Fields]) AND \"GAD\"[All Fields]) OR ((\"sep 363856\"[Supplementary Concept] OR \"sep 363856\"[All Fields] OR \"sep 363856\"[All Fields]) AND \"GAD\"[All Fields])" }, "MM120 GAD OR DT120 GAD": { "count": "2", "idlist": [ "42848417", "40906494" ], "translation": "(\"MM120\"[All Fields] AND \"GAD\"[All Fields]) OR (\"DT120\"[All Fields] AND \"GAD\"[All Fields])" } }, "isrctn": { "ISRCTN16993990": { "lastUpdated": "2026-10-21T15:32:20.011107143Z", "overallEndDate": "2026-10-30", "recruitmentEnd": "2026-04-02", "totalFinalEnrolment": "538", "targetEnrolment": "498", "publicationStage": "Protocol", "results": "empty" }, "date_range_query": { "q": "condition:anxiety lastEdited:2026-10-24T00:00:00.000Z TO 2026-11-01T00:00:00.000Z", "totalCount": 0 } }, "triage": { "added_pmids": [ "42924883", "42932137", "42928507", "42925400", "42957392" ], "added_preprint_doi": "10.64898/2026.10.21.26366048", "wiki_pages_edited": [ "wiki/red-flags-and-safety-concerns.md", "wiki/guidelines.md", "wiki/clinical-trials-landscape.md" ], "dropped_examples": [ "42933170 Zhang EEG n=29", "42934491 Cotton commentary", "42937060 Allan review (PubMed DOI mismatch)", "42929381 Nishiwaki Cochrane haemodialysis music", "42960975 Chiorean LSD depression MA", "PPR1349741 Jasti yoga pilot preprint n=20" ] }, "retraction_checks": { "pubmed_publication_types_clean": [ "42924883", "42932137", "42928507", "42925400", "42957392" ], "crossref_updated_by_empty": [ "10.1177/07067437261500231", "10.1007/s12306-026-00988-z", "10.1002/eat.70249", "10.1007/s10488-026-01532-8", "10.1016/j.rcpeng.2026.10.004", "10.64898/2026.10.21.26366048" ], "pubmed_doi_mismatches_resolved_via_crossref_title": { "42924883": "10.1177/07067437261500231", "42932137": "10.1007/s12306-026-00988-z", "42925400": "10.1007/s10488-026-01532-8" } } }