{ "condition": "depression", "date": "2026-10-15", "window": { "from": "2026-08-28", "to": "2026-10-15", "field": "publication date" }, "pubmed": [ { "topic": "diagnosis", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (diagnos* OR heterogeneity OR phenotype* OR screening OR \"mixed features\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"diagnos*\"[All Fields] OR (\"heterogeneic\"[All Fields] OR \"heterogeneities\"[All Fields] OR \"heterogeneity\"[All Fields] OR \"heterogeneous\"[All Fields] OR \"heterogeneously\"[All Fields] OR \"heterogenic\"[All Fields] OR \"heterogenicity\"[All Fields] OR \"heterogenities\"[All Fields] OR \"heterogenity\"[All Fields] OR \"heterogenization\"[All Fields] OR 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OR \"screens\"[All Fields]) OR \"mixed features\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "burden", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (epidemiology OR prevalence OR incidence OR \"global burden\" OR \"treatment gap\" OR registry) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"epidemiologies\"[All Fields] OR \"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"epidemiology s\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"prevalence\"[All Fields] OR \"prevalence\"[MeSH Terms] OR 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Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "mechanisms", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (neurobiolog* OR neuroinflamm* OR \"HPA axis\" OR BDNF OR \"neural circuit\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"neurobiolog*\"[All Fields] OR \"neuroinflamm*\"[All Fields] OR \"HPA axis\"[All Fields] OR (\"brain derived neurotrophic factor\"[Supplementary Concept] OR \"brain derived neurotrophic factor\"[All Fields] OR \"bdnf\"[All Fields] OR \"brain derived neurotrophic factor\"[MeSH Terms] OR (\"brain derived\"[All Fields] AND \"neurotrophic\"[All Fields] AND \"factor\"[All Fields])) OR \"neural circuit\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 146, "ids": [ "42874001", "42871390", "42870751", "42860592", "42858520", "42850268", "42842414", "42841964", "42840883", "42838181", "42828817", "42826818", "42826634", "42826581", "42819418", "42818885", "42817096", "42813034", "42810627", "42809944", "42807528", "42807520", "42806433", "42805955", "42805590", "42803524", "42797527", "42797287", "42794551", "42794424", "42793276", "42783499", "42778028", "42777979", "42773517", "42771937", "42771073", "42770453", "42770452", "42768143", "42767040", "42766483", "42765605", "42765387", "42764140", "42763338", "42762784", "42762770", "42762287", "42753853", "42752951", "42745799", "42745218", "42744142", "42737858", "42735276", "42734915", "42731592", "42729906", "42729560", "42728701", "42724084", "42723246", "42723086", "42721112", "42715443", "42710732", "42710718", "42710528", "42709645", "42707775", "42707762", "42707709", "42704208", "42702788", "42700763", "42696458", 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depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (genetic* OR GWAS OR polygenic OR epigenetic* OR ancestry) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"genetic*\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields]) OR (\"polygene\"[All Fields] OR \"polygenes\"[All Fields] OR \"polygenic\"[All Fields] OR \"polygenically\"[All Fields] OR \"polygenicity\"[All Fields]) OR \"epigenetic*\"[All Fields] OR (\"ancestries\"[All Fields] OR \"ancestry\"[All Fields])) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 145, "ids": [ "42874001", "42872493", "42871888", "42871390", "42862091", "42861501", "42858520", "42858466", "42856559", "42853203", "42850268", "42839001", "42836998", "42835756", "42834754", "42833865", "42831370", "42830219", "42829528", "42818443", "42818201", "42817096", "42814113", "42807520", "42807437", "42806433", "42803524", "42803521", "42803346", "42792438", "42791907", "42786261", "42785386", "42779037", "42778763", "42777979", "42773889", "42771937", "42771084", "42768143", "42767513", "42765387", "42765137", "42764573", "42760730", "42749774", "42749498", "42744145", "42742582", "42732835", "42728740", "42716055", "42715443", "42710732", "42710693", "42709645", "42706232", "42700945", "42696128", "42693300", "42688891", "42682166", "42679763", "42670435", "42669383", "42668072", "42667302", "42649423", "42649390", "42640306", "42633314", "42632223", "42630054", "42625058", "42623125", "42620154", "42613180", "42598999", "42595040", "42584886", "42580506", "42572938", "42569312", "42543058", "42537476", "42517234", "42485789", "42471042", "42462453", "42435748", "42425053", "42419634", "42418908", "42377483", "42364336", "42350629", "42320979", "42320287", "42320286", "42316910", "42314449", "42307972", "42296874", "42267832", "42252042", "42250361", "42230966", "42210495", "42203964", "42190845", "42178053", "42155857", "42144135", "42142759", "42134742", "42120555", "42119908", "42107849", "42105580", "42100925", "42098399", "42092578", "42092402", "42092400", "42055137", "42050011", "42047285", "42035806", "42035799", "42020763", "42020719", "42020718", "41968289", "41873584", "41845545", "41794061", "41791639", "41763442", "41761828", "41690355", "41605285", "41547389", "41534638", "40875158", "40204235" ] }, { "topic": "genetics", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (genetic* OR GWAS OR polygenic OR epigenetic* OR ancestry) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"genetic*\"[All Fields] OR (\"genome wide association study\"[MeSH Terms] OR (\"genome wide\"[All Fields] AND \"association\"[All Fields] AND \"study\"[All Fields]) OR \"genome wide association study\"[All Fields] OR \"gwas\"[All Fields]) OR (\"polygene\"[All Fields] OR \"polygenes\"[All Fields] OR \"polygenic\"[All Fields] OR \"polygenically\"[All Fields] OR \"polygenicity\"[All Fields]) OR \"epigenetic*\"[All Fields] OR (\"ancestries\"[All Fields] OR \"ancestry\"[All Fields])) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "antidepressants", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (antidepressant* OR SSRI OR SNRI OR withdrawal OR discontinuation OR \"sexual dysfunction\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"antidepressant*\"[All Fields] OR (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"serotonin and noradrenaline reuptake inhibitors\"[Pharmacological Action] OR \"serotonin and noradrenaline reuptake inhibitors\"[Supplementary Concept] OR \"serotonin and noradrenaline reuptake inhibitors\"[All Fields] OR \"snri\"[All Fields] OR \"serotonin and noradrenaline reuptake inhibitors\"[MeSH Terms] OR (\"serotonin\"[All Fields] AND \"noradrenaline\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"withdraw\"[All Fields] OR \"withdrawal\"[All Fields] OR \"withdrawals\"[All Fields] OR \"withdrawing\"[All Fields] OR \"withdraws\"[All Fields]) OR (\"discontinuance\"[All Fields] OR \"discontinuances\"[All Fields] OR \"discontinuated\"[All Fields] OR \"discontinuation\"[All Fields] OR \"discontinuations\"[All Fields] OR \"discontinue\"[All Fields] OR \"discontinued\"[All Fields] OR \"discontinuer\"[All Fields] OR \"discontinuers\"[All Fields] OR \"discontinues\"[All Fields] OR \"discontinuing\"[All Fields]) OR \"sexual dysfunction\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 205, "ids": [ "42871888", "42870348", "42869167", "42866549", "42863798", "42863557", "42861207", "42858801", "42858129", "42856566", "42850904", "42842414", "42841964", "42839386", "42838387", "42838181", "42835756", "42834741", "42832766", "42829528", "42826878", "42819418", "42818885", "42818515", "42817096", "42815037", "42814927", "42814111", "42812942", "42812643", "42812173", "42805662", "42805099", "42803521", "42801835", "42799904", "42797287", "42795930", "42795740", "42793276", "42792385", "42788073", "42786817", "42785392", "42784817", "42783499", "42778211", "42774912", "42770597", "42769822", "42769711", "42767626", "42767564", "42767040", "42766849", "42766673", "42766019", "42763552", "42762641", "42761770", "42756843", "42756839", "42753853", "42752587", "42751846", "42750362", "42750260", "42739877", "42736557", "42735274", "30725910", "28613681", "42732834", "42731592", "42729560", "42729393", "42729184", "42728072", "42727730", "42727635", "42725261", "42724084", "42722435", "42716345", "42716055", "42715443", "42715127", "42710716", "42710412", "42707709", "42705363", "42702010", "42701679", "42701110", "42700488", "42696738", "42696458", "42695158", "42692098", "42690086", "42688594", "42686996", "42684694", "42684061", "42682977", "42680855", "42680119", "42679360", "42674239", "42670957", "42668390", "42668254", "42668072", "42667302", "42665164", "42664168", "42663293", "42658027", "42642808", "42640306", "42640305", "42628206", "42621346", "42616023", "42610482", "42595101", "42595040", "42584886", "42581396", "42580506", "42572461", "42562964", "42556713", "42550483", "42532352", "42531622", "42522066", "42518156", "42508605", "42508527", "42508525", "42494826", "42492718", "42475069", "42470859", "42462453", "42455478", "42435731", "42418124", "42414566", "42413809", "42411994", "42410139", "42384049", "42379544", "42379141", "42362819", "42361653", "42341411", "42322911", "42307972", "42302638", "42284801", "42283956", "42276172", "42264040", "42263954", "42252042", "42250361", "42248243", "42242455", "42203004", "42176815", "42176813", "42169234", "42168587", "42167696", "42151503", "42131982", "42129477", "42127355", "42119282", "42115366", "42107656", "42105579", "42103244", "42086176", "42065494", "42055130", "42050011", "42047285", "42035805", "41986746", "41963179", "41904070", "41903946", "41873584", "41817153", "41814584", "41807319", "41804951", "41691708", "41558805", "41534638", "41111092" ] }, { "topic": "antidepressants", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (antidepressant* OR SSRI OR SNRI OR withdrawal OR discontinuation OR \"sexual dysfunction\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"antidepressant*\"[All Fields] OR (\"selective serotonin reuptake inhibitors\"[Pharmacological Action] OR \"selective serotonin reuptake inhibitors\"[Supplementary Concept] OR \"selective serotonin reuptake inhibitors\"[All Fields] OR \"ssri\"[All Fields] OR \"selective serotonin reuptake inhibitors\"[MeSH Terms] OR (\"selective\"[All Fields] AND \"serotonin\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"serotonin and noradrenaline reuptake inhibitors\"[Pharmacological Action] OR \"serotonin and noradrenaline reuptake inhibitors\"[Supplementary Concept] OR \"serotonin and noradrenaline reuptake inhibitors\"[All Fields] OR \"snri\"[All Fields] OR \"serotonin and noradrenaline reuptake inhibitors\"[MeSH Terms] OR (\"serotonin\"[All Fields] AND \"noradrenaline\"[All Fields] AND \"reuptake\"[All Fields] AND \"inhibitors\"[All Fields])) OR (\"withdraw\"[All Fields] OR \"withdrawal\"[All Fields] OR \"withdrawals\"[All Fields] OR \"withdrawing\"[All Fields] OR \"withdraws\"[All Fields]) OR (\"discontinuance\"[All Fields] OR \"discontinuances\"[All Fields] OR \"discontinuated\"[All Fields] OR \"discontinuation\"[All Fields] OR \"discontinuations\"[All Fields] OR \"discontinue\"[All Fields] OR \"discontinued\"[All Fields] OR \"discontinuer\"[All Fields] OR \"discontinuers\"[All Fields] OR \"discontinues\"[All Fields] OR \"discontinuing\"[All Fields]) OR \"sexual dysfunction\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "efficacy", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (\"publication bias\" OR placebo OR STAR*D OR \"clinical significance\" OR \"individual participant\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"publication bias\"[All Fields] OR (\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms]) OR \"star*d\"[All Fields] OR \"clinical significance\"[All Fields] OR \"individual participant\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 41, "ids": [ "42870348", "42863798", "42858520", "42815730", "42812942", "42802397", "42789363", "42778211", "42774912", "42766673", "42752587", "42733696", "42729393", "42721112", "42701110", "42690086", "42688558", "42684061", "42680855", "42680119", "42670051", "42610482", "42562964", "42550483", "42522066", "42494826", "42470859", "42455478", "42435731", "42414566", "42383744", "42350630", "42283956", "42252042", "42176815", "42176813", "42140323", "41963179", "41790247", "41558805", "41191045" ] }, { "topic": "efficacy", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (\"publication bias\" OR placebo OR STAR*D OR \"clinical significance\" OR \"individual participant\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"publication bias\"[All Fields] OR (\"placeboes\"[All Fields] OR \"placebos\"[Supplementary Concept] OR \"placebos\"[All Fields] OR \"placebo\"[All Fields] OR \"placebos\"[MeSH Terms]) OR \"star*d\"[All Fields] OR \"clinical significance\"[All Fields] OR \"individual participant\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "psychotherapy", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (psychotherap* OR \"cognitive behavioral\" OR \"behavioural activation\" OR exercise OR \"task sharing\" OR \"task-shared\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"psychotherap*\"[All Fields] OR \"cognitive behavioral\"[All Fields] OR \"behavioural activation\"[All Fields] OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR \"task sharing\"[All Fields] OR \"task-shared\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 109, "ids": [ "42872182", "42869999", "42865326", "42863798", "42863717", "42858129", "42854791", "42844936", "42843278", "42839301", "42838229", "42835728", "42834832", "42815884", "42812173", "42807040", "42805955", "42801310", "42799904", "42796411", "42795740", "42792385", "42789363", "42789054", "42785391", "42784817", "42779037", "42766019", "42756843", "42756688", "42750260", "42749161", "42736557", "42735276", "42734915", "42732835", "42732834", "42732542", "42726702", "42725261", "42724084", "42714093", "42710691", "42709645", "42700486", "42686352", "42682977", "42680855", "42679601", "42678888", "42669842", "42669383", "42664168", "42640306", "42632223", "42625058", "42612565", "42567088", "42562964", "42558024", "42550483", "42550193", "42518170", "42485789", "42475069", "42470859", "42435731", "42432162", "42425188", "42425030", "42418908", "42418124", "42413809", "42411994", "42384049", "42383885", "42379068", "42362819", "42294641", "42284801", "42269957", "42269542", "42263954", "42248243", "42217371", "42215638", "42184575", "42169234", "42155212", "42140319", "42134745", "42131982", "42129477", "42119908", "42119282", "42107658", "42096803", "42070700", "42047285", "42014469", "42002221", "41991348", "41807319", "41791639", "41787762", "41690355", "41558805", "40204235", "40184540" ] }, { "topic": "psychotherapy", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (psychotherap* OR \"cognitive behavioral\" OR \"behavioural activation\" OR exercise OR \"task sharing\" OR \"task-shared\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"psychotherap*\"[All Fields] OR \"cognitive behavioral\"[All Fields] OR \"behavioural activation\"[All Fields] OR (\"exercise\"[MeSH Terms] OR \"exercise\"[All Fields] OR \"exercises\"[All Fields] OR \"exercise therapy\"[MeSH Terms] OR (\"exercise\"[All Fields] AND \"therapy\"[All Fields]) OR \"exercise therapy\"[All Fields] OR \"exercising\"[All Fields] OR \"exercise s\"[All Fields] OR \"exercised\"[All Fields] OR \"exerciser\"[All Fields] OR \"exercisers\"[All Fields]) OR \"task sharing\"[All Fields] OR \"task-shared\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "resistance", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (\"treatment resistant\" OR \"treatment-resistant\" OR augmentation OR lithium OR sequencing) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"treatment-resistant\"[All Fields] OR \"treatment-resistant\"[All Fields] OR (\"augment\"[All Fields] OR \"augmentation\"[All Fields] OR \"augmentations\"[All Fields] OR \"augmented\"[All Fields] OR \"augmenting\"[All Fields] OR \"augments\"[All Fields]) OR (\"lithium\"[Supplementary Concept] OR \"lithium\"[All Fields] OR \"lithium\"[MeSH Terms] OR \"lithium s\"[All Fields] OR \"lithiums\"[All Fields]) OR (\"base sequence\"[MeSH Terms] OR (\"base\"[All Fields] AND \"sequence\"[All Fields]) OR \"base sequence\"[All Fields] OR \"sequence\"[All Fields] OR \"sequences\"[All Fields] OR \"sequence analysis\"[MeSH Terms] OR (\"sequence\"[All Fields] AND \"analysis\"[All Fields]) OR \"sequence analysis\"[All Fields] OR \"sequencing\"[All Fields] OR \"sequence s\"[All Fields] OR \"sequenceable\"[All Fields] OR \"sequenced\"[All Fields] OR \"sequenceing\"[All Fields] OR \"sequencer\"[All Fields] OR \"sequencers\"[All Fields] OR \"sequencies\"[All Fields] OR \"sequencings\"[All Fields])) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 145, "ids": [ "42870751", "42870348", "42869167", "42865326", "42864698", "42864498", "42863798", "42861501", "42858129", "42856359", "42849015", "42844676", "42844674", "42843471", "42841964", "42840696", "42831370", "42830219", "42829941", "42818885", "42818515", "42818201", "42817096", "42815730", "42814927", "42813034", "42812942", "42812173", "42807040", "42803524", "42799904", "42789054", "42788073", "42783499", "42783367", "42778763", "42771084", "42769103", "42768327", "42767040", "42766673", "42766497", "42766019", "42765892", "42762641", "42761770", "42760730", "42756843", "42756688", "42756176", "42753254", "42751846", "42749498", "42748866", "42745306", "42745218", "42744145", "42742966", "42736349", "30855854", "42732835", "42732834", "42732542", "42729848", "42728740", "42727730", "42721112", "42711407", "42702010", "42700945", "42700487", "42699006", "42690530", "42686996", "42684694", "42684061", "42682977", "42682166", "42679763", "42679236", "42678910", "42675468", "42668390", "42663266", "42658152", "42658027", "42649423", "42649390", "42642808", "42630054", "42625058", "42620154", "42613180", "42598999", "42580506", "42562964", "42542090", "42532352", "42531622", "42518156", "42517234", "42508605", "42502622", "42492720", "42435748", "42383744", "42379141", "42379068", "42377483", "42364336", "42339150", "42320287", "42307972", "42302659", "42302638", "42267832", "42248243", "42240040", "42230966", "42219697", "42210495", "42203964", "42144137", "42140321", "42127355", "42119282", "42107849", "42100925", "42065494", "42050011", "42035806", "42035799", "42020763", "42020719", "42020718", "41963179", "41904070", "41873584", "41814584", "41763442", "41761828", "41605285", "41558805", "41111092", "40875158" ] }, { "topic": "resistance", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (\"treatment resistant\" OR \"treatment-resistant\" OR augmentation OR lithium OR sequencing) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"treatment-resistant\"[All Fields] OR \"treatment-resistant\"[All Fields] OR (\"augment\"[All Fields] OR \"augmentation\"[All Fields] OR \"augmentations\"[All Fields] OR \"augmented\"[All Fields] OR \"augmenting\"[All Fields] OR \"augments\"[All Fields]) OR (\"lithium\"[Supplementary Concept] OR \"lithium\"[All Fields] OR \"lithium\"[MeSH Terms] OR \"lithium s\"[All Fields] OR \"lithiums\"[All Fields]) OR (\"base sequence\"[MeSH Terms] OR (\"base\"[All Fields] AND \"sequence\"[All Fields]) OR \"base sequence\"[All Fields] OR \"sequence\"[All Fields] OR \"sequences\"[All Fields] OR \"sequence analysis\"[MeSH Terms] OR (\"sequence\"[All Fields] AND \"analysis\"[All Fields]) OR \"sequence analysis\"[All Fields] OR \"sequencing\"[All Fields] OR \"sequence s\"[All Fields] OR \"sequenceable\"[All Fields] OR \"sequenced\"[All Fields] OR \"sequenceing\"[All Fields] OR \"sequencer\"[All Fields] OR \"sequencers\"[All Fields] OR \"sequencies\"[All Fields] OR \"sequencings\"[All Fields])) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "glutamatergic", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (ketamine OR esketamine OR dextromethorphan OR hydroxynorketamine OR zelquistinel) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"ketamin\"[All Fields] OR \"ketamine\"[Supplementary Concept] OR \"ketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"ketamine\"[MeSH Terms] OR \"ketamine s\"[All Fields] OR \"ketamines\"[All Fields] OR (\"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields]) OR (\"dextromethorphan\"[Supplementary Concept] OR \"dextromethorphan\"[All Fields] OR \"dextromethorphan\"[MeSH Terms] OR \"dextromethorphane\"[All Fields]) OR \"hydroxynorketamine\"[All Fields] OR \"zelquistinel\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 46, "ids": [ "42869167", "42865326", "42863798", "42858129", "42838387", "42835728", "42812942", "42803524", "42767564", "42767040", "42762641", "42756688", "42755741", "42748866", "42735276", "42721112", "42702010", "42692098", "42684694", "42682977", "42663266", "42616023", "42610482", "42572461", "42562964", "42556713", "42531622", "42522066", "42518156", "42508525", "42384049", "42377483", "42302638", "42240040", "42217548", "42151503", "42140321", "42103244", "42065494", "41873584", "41844563", "41814584", "41582323", "41191045", "41111092", "39964582" ] }, { "topic": "glutamatergic", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (ketamine OR esketamine OR dextromethorphan OR hydroxynorketamine OR zelquistinel) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"ketamin\"[All Fields] OR \"ketamine\"[Supplementary Concept] OR \"ketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields] OR \"ketamine\"[MeSH Terms] OR \"ketamine s\"[All Fields] OR \"ketamines\"[All Fields] OR (\"esketamine\"[Supplementary Concept] OR \"esketamine\"[All Fields]) OR (\"dextromethorphan\"[Supplementary Concept] OR \"dextromethorphan\"[All Fields] OR \"dextromethorphan\"[MeSH Terms] OR \"dextromethorphane\"[All Fields]) OR \"hydroxynorketamine\"[All Fields] OR \"zelquistinel\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "neuromodulation", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (electroconvulsive OR \"transcranial magnetic\" OR iTBS OR tDCS OR \"vagus nerve\" OR \"deep brain stimulation\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"electroconvulsant\"[All Fields] OR \"electroconvulsion\"[All Fields] OR \"electroconvulsions\"[All Fields] OR \"electroconvulsive\"[All Fields] OR \"transcranial magnetic\"[All Fields] OR \"iTBS\"[All Fields] OR (\"transcranial direct current stimulation\"[MeSH Terms] OR (\"transcranial\"[All Fields] AND \"direct\"[All Fields] AND \"current\"[All Fields] AND \"stimulation\"[All Fields]) OR \"transcranial direct current stimulation\"[All Fields] OR \"tdcs\"[All Fields]) OR \"vagus nerve\"[All Fields] OR \"deep brain stimulation\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 91, "ids": [ "42870348", "42864698", "42863719", "42863253", "42860592", "42858129", "42855128", "42844676", "42844674", "42843471", "42841964", "42839296", "42838181", "42830939", "42829057", "42829029", "42818515", "42810830", "42801310", "42799904", "42789363", "42789054", "42787626", "42785385", "42785233", "42783367", "42769949", "42766673", "42766019", "42762784", "42753347", "42745306", "42745218", "42735276", "30855854", "42731592", "42727730", "42721517", "42721112", "42700487", "42700486", "42699697", "42696738", "42687377", "42686996", "42679601", "42679236", "42676877", "42675468", "42674239", "42668924", "42658152", "42642808", "42628206", "42595040", "42581396", "42518170", "42508605", "42502622", "42492720", "42475069", "42398293", "42384049", "42383744", "42341411", "42339150", "42335495", "42302659", "42284801", "42272332", "42265226", "42252042", "42223086", "42219697", "42155351", "42127355", "42115366", "42107658", "42090938", "42086176", "42035805", "41986746", "41862185", "41814584", "41807319", "41690355", "40228165", "40184540", "40168143", "40132108", "39964582" ] }, { "topic": "neuromodulation", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (electroconvulsive OR \"transcranial magnetic\" OR iTBS OR tDCS OR \"vagus nerve\" OR \"deep brain stimulation\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"electroconvulsant\"[All Fields] OR \"electroconvulsion\"[All Fields] OR \"electroconvulsions\"[All Fields] OR \"electroconvulsive\"[All Fields] OR \"transcranial magnetic\"[All Fields] OR \"iTBS\"[All Fields] OR (\"transcranial direct current stimulation\"[MeSH Terms] OR (\"transcranial\"[All Fields] AND \"direct\"[All Fields] AND \"current\"[All Fields] AND \"stimulation\"[All Fields]) OR \"transcranial direct current stimulation\"[All Fields] OR \"tdcs\"[All Fields]) OR \"vagus nerve\"[All Fields] OR \"deep brain stimulation\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "novel", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (psilocybin OR psychedelic* OR neurosteroid* OR zuranolone OR brexanolone OR CYB003 OR GM-2505) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"psilocybin\"[Supplementary Concept] OR \"psilocybin\"[All Fields] OR \"psilocybin\"[MeSH Terms] OR \"psilocybine\"[All Fields] OR \"psilocybin s\"[All Fields] OR \"psychedelic*\"[All Fields] OR \"neurosteroid*\"[All Fields] OR (\"zuranolone\"[Supplementary Concept] OR \"zuranolone\"[All Fields]) OR (\"brexanolone\"[Supplementary Concept] OR \"brexanolone\"[All Fields]) OR \"GM-2505\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 21, "ids": [ "42869167", "42865326", "42835728", "42834832", "42809944", "42750260", "42735276", "42732542", "42663266", "42658027", "42580506", "42562964", "42531622", "42414566", "42379141", "42320287", "42302638", "42252042", "42215638", "41963179", "41191045" ] }, { "topic": "novel", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (psilocybin OR psychedelic* OR neurosteroid* OR zuranolone OR brexanolone OR CYB003 OR GM-2505) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"psilocybin\"[Supplementary Concept] OR \"psilocybin\"[All Fields] OR \"psilocybin\"[MeSH Terms] OR \"psilocybine\"[All Fields] OR \"psilocybin s\"[All Fields] OR \"psychedelic*\"[All Fields] OR \"neurosteroid*\"[All Fields] OR (\"zuranolone\"[Supplementary Concept] OR \"zuranolone\"[All Fields]) OR (\"brexanolone\"[Supplementary Concept] OR \"brexanolone\"[All Fields]) OR \"GM-2505\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "prediction", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (biomarker* OR pharmacogen* OR prediction OR \"machine learning\" OR \"digital phenotyping\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"biomarker*\"[All Fields] OR \"pharmacogen*\"[All Fields] OR (\"predict\"[All Fields] OR \"predictabilities\"[All Fields] OR \"predictability\"[All Fields] OR \"predictable\"[All Fields] OR \"predictably\"[All Fields] OR \"predicted\"[All Fields] OR \"predicting\"[All Fields] OR \"prediction\"[All Fields] OR \"predictions\"[All Fields] OR \"predictive\"[All Fields] OR \"predictively\"[All Fields] OR \"predictiveness\"[All Fields] OR \"predictives\"[All Fields] OR \"predictivities\"[All Fields] OR \"predictivity\"[All Fields] OR \"predicts\"[All Fields]) OR \"machine learning\"[All Fields] OR \"digital phenotyping\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 267, "ids": [ "42874811", "42873387", "42872493", "42872182", "42871667", "42871390", "42870751", "42869999", "42866549", "42863253", "42861501", "42861312", "42860592", "42858801", "42858129", "42856566", "42856559", "42855128", "42851958", "42846268", "42844674", "42843469", "42843279", "42841964", "42840883", "42840696", "42839301", "42838181", "42834754", "42833865", "42833406", "42832644", "42831370", "42830939", "42829528", "42829057", "42826878", "42826821", "42826818", "42826767", "42826634", "42826067", "42822715", "42822187", "42820260", "42818201", "42815884", "42815731", "42813034", "42812173", "42811409", "42810830", "42810627", "42806848", "42806433", "42805955", "42805099", "42803524", "42801835", "42799620", "42797527", "42796411", "42794622", "42794551", "42794424", "42792438", "42792385", "42791907", "42788145", "42787777", "42787408", "42785393", "42785392", "42785391", "42785390", "42783499", "42780703", "42777933", "42775302", "42774912", "42773889", "42771937", "42771084", "42770453", "42769822", "42767042", "42766673", "42766019", "42765861", "42765605", "42764573", "42763552", "42758600", "42756843", "42756839", "42756176", "42755741", "42754579", "42753347", "42753254", "42752951", "42752567", "42752290", "42752169", "42751051", "42749778", "42748377", "42745834", "42744142", "42739724", "42737858", "42736557", "42735276", "42734915", "30725910", "42732880", "42732835", "42731592", "42729848", "42726936", "42726702", "42726636", "42725756", "42722301", "42721164", "42721112", "42719402", "42717271", "42716347", "42716055", "42710732", "42710693", "42710691", "42710528", "42710412", "42709645", "42709166", "42707775", "42706232", "42705363", "42702788", "42700763", "42700487", "42699697", "42699006", "42698909", "42698872", "42696128", "42686996", "42686088", "42685988", "42684674", "42682166", "42676104", "42669383", "42668072", "42664168", "42663293", "42660575", "42642808", "42640306", "42636957", "42633856", "42625058", "42624134", "42623125", "42622332", "42621346", "42616023", "42612565", "42598032", "42572938", "42572461", "42565167", "42561530", "42558024", "42546834", "42546815", "42543058", "42542090", "42528344", "42522354", "42522066", "42498564", "42494826", "42492720", "42492718", "42485972", "42474069", "42471518", "42471042", "42470859", "42462453", "42462416", "42435240", "42425053", "42419634", "42414566", "42413809", "42410139", "42399489", "42398293", "42379544", "42379070", "42377483", "42364336", "42362819", "42342066", "42341411", "42337416", "42330683", "42320286", "42307972", "42302638", "42297310", "42276172", "42263954", "42252042", "42250253", "42230966", "42211077", "42210495", "42168587", "42155212", "42151503", "42140323", "42134744", "42131982", "42129477", "42127355", "42120555", "42119909", "42119908", "42107656", "42103244", "42100925", "42092578", "42092400", "42090938", "42086176", "42070700", "42069105", "42055138", "42055130", "42053632", "42050011", "42049068", "42047285", "42044556", "42035806", "42035799", "42031013", "42014469", "42013686", "41986746", "41947665", "41880255", "41817153", "41807319", "41762174", "41581557", "41547389", "41534638", "41191045", "40996024", "40935332", "40689925" ] }, { "topic": "prediction", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (biomarker* OR pharmacogen* OR prediction OR \"machine learning\" OR \"digital phenotyping\") AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"biomarker*\"[All Fields] OR \"pharmacogen*\"[All Fields] OR (\"predict\"[All Fields] OR \"predictabilities\"[All Fields] OR \"predictability\"[All Fields] OR \"predictable\"[All Fields] OR \"predictably\"[All Fields] OR \"predicted\"[All Fields] OR \"predicting\"[All Fields] OR \"prediction\"[All Fields] OR \"predictions\"[All Fields] OR \"predictive\"[All Fields] OR \"predictively\"[All Fields] OR \"predictiveness\"[All Fields] OR \"predictives\"[All Fields] OR \"predictivities\"[All Fields] OR \"predictivity\"[All Fields] OR \"predicts\"[All Fields]) OR \"machine learning\"[All Fields] OR \"digital phenotyping\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "mortality-safety", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (suicid* OR mortality OR safety OR \"adverse effect\" OR mania OR overdose) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"suicid*\"[All Fields] OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR \"adverse effect\"[All Fields] OR (\"mania\"[MeSH Terms] OR \"mania\"[All Fields] OR \"manias\"[All Fields]) OR (\"drug overdose\"[MeSH Terms] OR (\"drug\"[All Fields] AND \"overdose\"[All Fields]) OR \"drug overdose\"[All Fields] OR \"overdose\"[All Fields] OR \"overdoses\"[All Fields] OR \"overdosed\"[All Fields] OR \"overdosing\"[All Fields])) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 201, "ids": [ "42872469", "42871667", "42870751", "42866044", "42863798", "42862594", "42862569", "42861207", "42856559", "42855248", "42851958", "42849853", "42849015", "42844676", "42841964", "42841689", "42840913", "42840696", "42838387", "42837291", "42835728", "42830939", "42829833", "42822715", "42818443", "42817096", "42815731", "42814927", "42812942", "42809770", "42804205", "42802397", "42801835", "42799588", "42797287", "42792450", "42788073", "42787626", "42785386", "42785385", "42783499", "42780377", "42779163", "42779162", "42778211", "42774912", "42768327", "42767564", "42767042", "42766849", "42766019", "42765892", "42764573", "42764140", "42758600", "42757108", "42756688", "42755741", "42753853", "42753254", "42752169", "42751846", "42750260", "42745306", "42745218", "42742582", "42739724", "42737920", "42736557", "42734915", "30855854", "30725910", "28613681", "42732835", "42732834", "42732542", "42731592", "42731320", "42729393", "42727204", "42725756", "42722619", "42721198", "42721164", "42720675", "42714373", "32644424", "42710718", "42710716", "42710412", "42706232", "31747213", "42705422", "42701679", "42701110", "42698177", "42698078", "42696738", "42696532", "42693223", "42692098", "42689366", "42687377", "42686352", "42686074", "42685988", "42684694", "42684674", "42682977", "42680855", "42679236", "42678910", "42670435", "42668390", "42663608", "42663293", "42663266", "42658152", "42658027", "42649425", "42642808", "42633856", "42628206", "42616023", "42610482", "42584886", "42581396", "42571148", "42562964", "42518156", "42517234", "42508605", "42502622", "42494826", "42470859", "42455478", "42425098", "42419463", "42410139", "42399489", "42361653", "42335495", "42320979", "42320286", "42314447", "42310163", "42307972", "42302888", "42301395", "42298346", "42296874", "42284804", "42283956", "42269542", "42267832", "42265226", "42250361", "42240040", "42223086", "42217371", "42215638", "42210495", "42203004", "42173043", "42169234", "42167697", "42167696", "42155351", "42155212", "42144137", "42140319", "42134004", "42131982", "42115366", "42107658", "42107653", "42106071", "42105579", "42092398", "42069105", "42055137", "42031014", "42031013", "42014469", "42013686", "42002221", "41968289", "41963179", "41947665", "41817153", "41804951", "41790247", "41758223", "41691708", "41558805", "41429013", "41319841", "41247288", "41111092", "40132108", "39964582" ] }, { "topic": "mortality-safety", "cochrane": true, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (suicid* OR mortality OR safety OR \"adverse effect\" OR mania OR overdose) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication]) AND \"Cochrane Database Syst Rev\"[jour]", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"suicid*\"[All Fields] OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"safety\"[MeSH Terms] OR \"safety\"[All Fields] OR \"safeties\"[All Fields]) OR \"adverse effect\"[All Fields] OR (\"mania\"[MeSH Terms] OR \"mania\"[All Fields] OR \"manias\"[All Fields]) OR (\"drug overdose\"[MeSH Terms] OR (\"drug\"[All Fields] AND \"overdose\"[All Fields]) OR \"drug overdose\"[All Fields] OR \"overdose\"[All Fields] OR \"overdoses\"[All Fields] OR \"overdosed\"[All Fields] OR \"overdosing\"[All Fields])) AND 2026/08/28:2026/10/15[Date - Publication] AND \"Cochrane Database Syst Rev\"[Journal]", "count": 0, "ids": [] }, { "topic": "guidelines", "cochrane": false, "query": "(\"Depressive Disorder, Major\"[Mesh] OR \"major depression\"[tiab] OR \"major depressive\"[tiab] OR \"unipolar depression\"[tiab]) AND (guideline[pt] OR practice guideline[pt] OR consensus OR recommendation*) AND (\"2026/08/28\"[Date - Publication] : \"2026/10/15\"[Date - Publication])", "translation": "(\"major depression\"[Title/Abstract] OR \"major depressive\"[Title/Abstract] OR \"unipolar depression\"[Title/Abstract]) AND (\"guideline\"[Publication Type] OR \"practice guideline\"[Publication Type] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields]) OR \"recommendation*\"[All Fields]) AND 2026/08/28:2026/10/15[Date - Publication]", "count": 26, "ids": [ "42854791", "42832766", "42814927", "42801835", "42797527", "42789363", "42788073", "42783499", "42766019", "42756688", "42745306", "30725910", "42696738", "42658152", "42572938", "42533130", "42518156", "42411994", "42410139", "42314447", "42105580", "42092400", "42035799", "42020763", 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