{ "condition": "colorectal-adenocarcinoma", "date": "2026-10-19", "engine": "Grok, grok-4.6", "window": { "from": "2026-08-28", "to": "2026-10-19", "field": "publication date; plus entrez from 2026-10-12" }, "sources_queried": [ "PubMed E-utilities esearch/esummary/efetch", "Europe PMC REST search", "ClinicalTrials.gov API v2", "Crossref works/{doi} updated-by", "ISRCTN portal (STAR-TREC ISRCTN14240288 search attempted)", "EU CTR query 2014-003601-15", "WHO ICTRP portal (HTTP 200, JS-driven; not counted as searched)", "ChiCTR search page HTTP 200 (JS)", "Society pages: ACS screening, USPSTF, ACG, ESMO news/mCRC, NCCN colon/rectal, NICE NG151/history, IARC GCO", "Patient orgs: Fight CRC, Colorectal Cancer Alliance, Bowel Cancer UK, Colostomy UK" ], "sources_not_queried": [ "Cochrane Library/CENTRAL (HTTP 403)", "SciELO/LILACS (HTTP 403)", "ASCO guidelines page (HTTP 403)", "Bowel Cancer Australia (HTTP 403)", "SEER statfacts timeout", "Unpaywall skipped (LIFEBANK_CONTACT_EMAIL unset)", "Embase/Scopus/WoS (no credentials)" ], "pubmed": [ { "topic": "burden-young-onset", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (epidemiolog* OR incidence OR mortality OR burden OR GLOBOCAN OR GBD OR disparit* OR \"early-onset\" OR \"young-onset\" OR \"early onset\" OR \"birth cohort\") AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"epidemiolog*\"[All Fields] OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields]) OR (\"mortality\"[MeSH Terms] OR \"mortality\"[All Fields] OR \"mortalities\"[All Fields] OR \"mortality\"[MeSH Subheading]) OR (\"burden\"[All Fields] OR \"burdened\"[All Fields] OR \"burdening\"[All Fields] OR \"burdens\"[All Fields]) OR \"GLOBOCAN\"[All Fields] OR \"GBD\"[All Fields] OR \"disparit*\"[All Fields] OR \"early-onset\"[All Fields] OR \"young-onset\"[All Fields] OR \"early-onset\"[All Fields] OR \"birth cohort\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 1075, "ids": [ "42607643", "42763868", "42320666", "42502958", "42445966", "42424525", "42376755", "42322272", "42246276", "42141809", "42100890", "41947036", "42398657", "42892808", "42848519", "42830811", "42825377", "42824630", "42787936", "42743653", "42700379", "42656596", "42638413", "42628218", "42616478", "42597294", "42550740", "42509642", "42501831", "42449506", "42421558", "42421205", "42394524", "42388227", "42384957", "42339709", "42311093", "42300690", "42240008", "42229304", "42037577", "42003703", "41879223", "41860526", "41860356", "41858760", "41601288", "41549778", "41492104", "41481139", "41454717", "41454575", "41052213", "42660439", "42538607", "42360685", "42322026", "42322011", "42259422", "42140106", "42888865", "42871306", "42835719", "42791320", "42763522", "42761845", "42733664", "42731452", "42725398", "42716462", "42702456", "42702203", "42692037", "42685928", "42685927", "42685490", "42685390", "42681563", "42660345", "42648206", "42640147", "42632483", "42618857", "42537713", "42537286", "42536096", "42533014", "42526771", "42520535", "42501829", "42460779", "42458051", "42456992", "42423930", "42420696", "42333995", "42298759", "42142768", "42142103", "42053092", "39998985", "42722050", "42893597", "42893802", "42893452", "42892709", "42892521", "42892101", "42891625", "42888599", "42888581", "42888568", "42888297", "42887539", "42886720", "42886614", "42886393", "42886269", "42885719", "42885592", "42743888", "42891491", "42886465", "42881315", "42880456", "42879326", "42879114", "42879099", "42878900", "42754466", "42743607", "42555229", "42525957", "42272324", "42226376", "42198797", "42186152", "42104745", "42887195", "42875946", "42875341", "42874958", "42874631", "42874265", "42872459", "42870741", "42892179", "42885270", "42879982", "42869589", "42869126", "42867594", "42867251", "42867138", "42865226", "42879642", "42870228", "42864133", "42863976", "42863462", "42862093", "42861870", "42861640", "42861616", "42860519", "42860475", "42868791", "42859933", "42858832", "42858024", "42849474", "42849473", "42849472", "42525921", "42855147", "42854450", "42854379", "42853717", "42853669", "42853540", "42852861", "42871149", "42853287", "42851759", "42850897", "42848099", "42847809", "42847277", "42847179", "42629258", "42882920", "42860120", "42847721", "42844369", "42843632", "42843098", "42842497", "42842020", "42839802", "42789753" ], "http": 200 }, { "topic": "carcinogenesis-serrated", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (adenoma OR serrated OR polyp* OR \"adenoma-carcinoma\" OR precursor OR field-effect OR \"field effect\") AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"adenoma\"[MeSH Terms] OR \"adenoma\"[All Fields] OR \"adenomas\"[All Fields] OR \"adenoma s\"[All Fields] OR (\"serrate\"[All Fields] OR \"serrated\"[All Fields] OR \"serration\"[All Fields] OR \"serrations\"[All Fields]) OR \"polyp*\"[All Fields] OR \"adenoma-carcinoma\"[All Fields] OR (\"precursor\"[All Fields] OR \"precursor s\"[All Fields] OR \"precursors\"[All Fields]) OR \"field-effect\"[All Fields] OR \"field-effect\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 281, "ids": [ "42831183", "42722114", "42740607", "42083308", "41693466", "42540399", "42339709", "42229304", "42186437", "42048609", "41879223", "41858052", "42322011", "42140106", "42866245", "42702203", "42680813", "42662364", "42632257", "42607381", "42606680", "42520535", "42423930", "42420696", "42637393", "42546913", "42891902", "42888642", "42887539", "42887063", "42886590", "42887343", "42879099", "42877611", "42872459", "42868089", "42867948", "42865227", "42861489", "42879989", "42853879", "42851190", "42844151", "42844080", "42843632", "42842625", "41791848", "41629149", "42838765", "42837662", "42868947", "42848678", "42832574", "42831658", "42659836", "41334638", "42835528", "42882890", "42827107", "42834226", "42823104", "42821450", "42817615", "42803145", "42726205", "42692776", "42692775", "42692773", "42692771", "42686234", "42604010", "42602254", "42600473", "42595629", "42594997", "42575119", "42562459", "42557487", "42550607", "42542651", "42537464", "42492394", "42486928", "42486255", "42462747", "42449149", "42439066", "42393851", "42365851", "42364787", "42337207", "42333415", "42332159", "42331035", "42328851", "42309220", "42288690", "42268358", "42247954", "42184673", "42166773", "42142544", "42095296", "42065991", "42009205", "41935575", "41905521", "41744399", "41738599", "41677132", "41574731", "42816164", "42815038", "42815019", "42814894", "42814501", "42814066", "42814045", "42409544", "42806646", "42883903", "42812795", "42807744", "42806489", "42805219", "42803928", "42849137", "42801967", "42884295", "42883185", "42857378", "42818236", "42790904", "42789583", "42789018", "42784499", "42782065", "42883746", "42882777", "42880085", "42846800", "42807415", "42778665", "42776302", "42775892", "42580755", "42882772", "42840404", "42770890", "42635437", "42835332", "42795028", "42768279", "42766390", "42794806", "42787060", "42772256", "42669487", "42760086", "42759679", "42757588", "42869761", "42794977", "42782784", "42761157", "42754129", "42753019", "42753012", "42752748", "42748438", "42748427", "42549036", "20301390", "42743896", "42741799", "42687847", "42574033", "42574029", "42574027", "42574019", "32809560", "42728437", "42728028", "42725569", "42794907", "42792985", "42792192", "42720829", "42714031", "42710753", "42684144", "42709018", "42845707", "42737845", "42703166", "41314787", "42737839", "42868921", "42707445", "42808355" ], "http": 200 }, { "topic": "molecular-subtypes", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (CMS OR \"consensus molecular\" OR microenvironment OR MSI OR microsatellite OR CIN OR \"chromosomal instability\") AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"comput manag sci\"[Journal] OR \"comp migr stud\"[Journal] OR \"commun math stat\"[Journal] OR \"clin mass spectrom\"[Journal] OR \"cms\"[All Fields] OR \"consensus molecular\"[All Fields] OR (\"microenvironment\"[All Fields] OR \"microenvironment s\"[All Fields] OR \"microenvironments\"[All Fields]) OR \"MSI\"[All Fields] OR (\"microsatellite repeats\"[MeSH Terms] OR (\"microsatellite\"[All Fields] AND \"repeats\"[All Fields]) OR \"microsatellite repeats\"[All Fields] OR \"microsatellite\"[All Fields] OR \"microsatellites\"[All Fields]) OR (\"comput nurs\"[Journal] OR \"comput intell neurosci\"[Journal] OR \"comput inform nurs\"[Journal] OR \"cin\"[All Fields]) OR \"chromosomal instability\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 493, "ids": [ "42607643", "42822256", "42763869", "42763868", "42763867", "42751120", "42699228", "42419183", "42689729", "42445966", "42424525", "42393838", "42322272", "42212684", "42084500", "41981741", "41815020", "41723598", "41424360", "42702174", "42787548", "42756777", "42668486", "42628218", "42616478", "42576420", "42574980", "42550740", "42433082", "42391989", "42186437", "41742891", "41454575", "42625524", "42259422", "42890799", "42852635", "42835784", "42811483", "42777649", "42762965", "42757455", "42731420", "42715652", "42685927", "42685490", "42640147", "42624032", "42618857", "42612350", "42606680", "42574910", "42546883", "42520374", "42456992", "42448134", "42402363", "42335647", "42546913", "42648821", "42892709", "42892101", "42887494", "42887063", "42885719", "42857707", "42835088", "42828282", "42879954", "42879114", "42879043", "42879037", "42876326", "42754466", "42525957", "42503264", "42489533", "42484294", "42217373", "42887195", "42875546", "42874991", "42874989", "42869393", "42879982", "42875754", "42872124", "42869126", "42879103", "42864387", "42863469", "42860799", "42858844", "42526530", "42525921", "42879989", "42842645", "42848258", "42848099", "42844247", "42714955", "42882920", "42844848", "42843574", "42842020", "42841377", "41980760", "41748160", "42874305", "42840394", "42839693", "42839014", "42838996", "42838491", "42837794", "42837177", "42837080", "42714160", "42832699", "42830694", "42830367", "42830873", "42829935", "42829798", "42884079", "42890735", "42890516", "42861819", "42828116", "42827107", "42461083", "42418705", "42889836", "42889067", "42882868", "42882498", "42864774", "42860655", "42823149", "42823087", "42822843", "42822680", "42821536", "42820775", "42820689", "42820669", "42817716", "42816767", "42806446", "42781069", "42780999", "42774497", "42733940", "42726205", "42703026", "42618801", "42615888", "42607848", "42602254", "42598205", "42595201", "42594762", "42592954", "42585889", "42567390", "42562459", "42562297", "42556459", "42556129", "42551539", "42546403", "42542401", "42541898", "42535319", "42532356", "42531881", "42520477", "42520384", "42508143", "42493268", "42468791", "42462480", "42461618", "42431243", "42413716", "42413310", "42407177", "42362102", "42360182", "42342021", "42323172", "42315073", "42309220", "42297063", "42263871", "42213274", "42184673", "42176680", "42166037", "42154581" ], "http": 200 }, { "topic": "hereditary-genetics", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (Lynch OR FAP OR polyposis OR germline OR hereditary OR \"mismatch repair\" OR MLH1 OR MSH2 OR APC[tiab]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"lynch\"[All Fields] OR \"lynch s\"[All Fields] OR \"FAP\"[All Fields] OR \"polyposis\"[All Fields] OR (\"germline\"[All Fields] OR \"germlines\"[All Fields]) OR \"hereditary\"[All Fields] OR \"mismatch repair\"[All Fields] OR (\"mlh1 protein human\"[Supplementary Concept] OR \"mlh1 protein human\"[All Fields] OR \"mlh1\"[All Fields]) OR \"MSH2\"[All Fields] OR \"APC\"[Title/Abstract]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 256, "ids": [ "42867783", "42845214", "42665998", "42424525", "42376755", "42141809", "41693466", "42787548", "42727165", "42656596", "42641839", "42576420", "42540399", "42889706", "42538607", "42431843", "42890799", "42702203", "42692037", "42662364", "42604092", "42423930", "39998985", "42748573", "42546913", "42288229", "42893802", "42892709", "42885719", "42787574", "42879099", "42879043", "42878963", "42198797", "42872622", "42550992", "42526530", "42525921", "42853888", "42851190", "42844118", "42407056", "42882920", "42847237", "42843898", "42842020", "42841377", "41980760", "41748160", "42884735", "42874305", "42838765", "42868947", "42833850", "42831658", "42882890", "42854555", "42890735", "42833137", "42882498", "42834226", "42823185", "42822843", "42821536", "42820775", "42820669", "42803145", "42781069", "42780999", "42746058", "42702960", "42686234", "42607848", "42605004", "42594997", "42594762", "42591015", "42552405", "42550607", "42542401", "42537281", "42494233", "42492394", "42486928", "42462747", "42449149", "42439066", "42413738", "42413716", "42364787", "42328851", "42309220", "42283096", "42269873", "42126206", "41935575", "41738599", "41686095", "42870843", "42870803", "42814894", "42814501", "42814066", "42814045", "42813581", "42856513", "42806646", "42883903", "42866390", "42865464", "42812795", "42806659", "42269807", "42801369", "42799816", "42857020", "42808537", "42790910", "42789554", "42778117", "42775551", "42771175", "42770890", "42721032", "42835854", "42831105", "42767903", "42787060", "42772256", "42827653", "42795000", "42758302", "42757994", "42701426", "42761157", "42753019", "42753012", "42748024", "20301390", "42794953", "42751329", "42749910", "42812258", "42764742", "42744133", "42092475", "41672528", "42806967", "42802880", "32809560", "42794922", "30335319", "42798494", "42795834", "42736804", "42731846", "42728028", "42721065", "42736686", "42731507", "42720829", "42720705", "42794454", "42781368", "42780443", "42780147", "42724513", "42717387", "42716685", "42714885", "42407299", "42719515", "42710647", "42709325", "42709142", "42845707", "42769402", "42738783", "42738397", "42808355", "42765567", "42725584", "42776613", "42755920", "42755803", "42828412", "42686374", "42684488", "42762518", "42753220", "42749394", "42729714", "42725239", "42688374", "42683623", "42683498", "42682916", "42680252", "42676920", "42674816" ], "http": 200 }, { "topic": "screening", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (screening OR FIT OR \"fecal immunochemical\" OR colonoscopy OR \"stool DNA\" OR \"blood-based\" OR \"multi-cancer\" OR sigmoidoscopy) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields] OR (\"seizures\"[MeSH Terms] OR \"seizures\"[All Fields] OR \"fit\"[All Fields]) OR \"fecal immunochemical\"[All Fields] OR (\"colonoscopy\"[MeSH Terms] OR \"colonoscopy\"[All Fields] OR \"colonoscopies\"[All Fields]) OR \"stool DNA\"[All Fields] OR \"blood-based\"[All Fields] OR \"multi-cancer\"[All Fields] OR (\"sigmoidoscopy\"[MeSH Terms] OR \"sigmoidoscopy\"[All Fields] OR \"sigmoidoscopies\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 1077, "ids": [ "42582810", "42111927", "42556455", "42392486", "42759314", "42700497", "42673642", "42641376", "42485955", "42748722", "42826819", "42822256", "42751120", "42722114", "42476089", "42391702", "42320666", "42288274", "42285341", "42381379", "42212684", "41693466", "42850846", "42702174", "42700477", "42648057", "42875898", "42848519", "42840411", "42824630", "42821825", "42787548", "42743653", "42727165", "42723442", "42700379", "42679640", "42612398", "42600521", "42597294", "42562283", "42508240", "42464785", "42449506", "42433082", "42394524", "42358730", "42339709", "42323914", "42318678", "42300690", "42296870", "42296867", "42274165", "42253188", "42240008", "42229304", "42209292", "42165203", "42003703", "41879223", "41860526", "41852759", "41764032", "41732288", "41721713", "41709507", "41566772", "41492998", "41492864", "41052213", "42889706", "42625524", "42322026", "42322011", "42176610", "42815373", "42722218", "42361483", "42140106", "42890799", "42888865", "42871306", "42866245", "42855213", "42855208", "42855207", "42855206", "42840437", "42835719", "42769717", "42763522", "42762965", "42751104", "42741551", "42725398", "42715652", "42702456", "42702203", "42692037", "42685390", "42664864", "42660345", "42641315", "42641254", "42623858", "42618857", "42606023", "42556052", "42536096", "42533014", "42520535", "42520374", "42493692", "42458051", "42435230", "42423930", "42420696", "42402363", "42399198", "42372925", "42341192", "42142103", "42648821", "42893597", "42893452", "42892709", "42892442", "42891705", "42892101", "42891625", "42891583", "42891063", "42888642", "42888599", "42888581", "42888372", "42887741", "42887539", "42887538", "42886720", "42886614", "42886590", "42886530", "42885807", "42885719", "42885592", "42857707", "42787574", "42892154", "42887343", "42879954", "42879099", "42879037", "42876326", "42767173", "42748748", "42748746", "42743607", "42731188", "42685445", "42484294", "42263581", "42226376", "42217374", "42186152", "41672537", "42877611", "42875946", "42875341", "42874958", "42874443", "42872459", "42870741", "42869393", "42869123", "42868089", "42867948", "42867167", "42867138", "42865227", "42865226", "42734185", "42403340", "42870228", "42864133", "42862502", "42862093", "42861870", "42861640", "42861616", "42861572", "42860475", "42860445", "42859933", "42858159", "42858024", "42849474", "42849473", "42849472" ], "http": 200 }, { "topic": "pathology-staging", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (patholog* OR staging OR TNM OR budding OR MMR OR immunohistochemistry OR \"circumferential resection\") AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"patholog*\"[All Fields] OR (\"stage\"[All Fields] OR \"staged\"[All Fields] OR \"stages\"[All Fields] OR \"staging\"[All Fields] OR \"stagings\"[All Fields]) OR \"TNM\"[All Fields] OR (\"budded\"[All Fields] OR \"budding\"[All Fields] OR \"buddings\"[All Fields]) OR (\"mil med res\"[Journal] OR \"mmr\"[All Fields]) OR (\"immunohistochemistries\"[All Fields] OR \"immunohistochemistry\"[MeSH Terms] OR \"immunohistochemistry\"[All Fields]) OR \"circumferential resection\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 1579, "ids": [ "42781356", "42441083", "42256611", "42392486", "42700497", "42685539", "42673642", "42476202", "42867783", "42826819", "42822256", "42763869", "42763868", "42763867", "42763865", "42722114", "42476089", "42320666", "42288274", "42845214", "42689729", "42665998", "42525450", "42507757", "42502958", "42445966", "42424525", "42393838", "42378068", "42376755", "42345355", "42324593", "42322272", "42246276", "42141998", "42141809", "42100890", "42084802", "42084500", "42083308", "41963777", "41947036", "41873832", "41815020", "41742461", "41723598", "41693466", "41424360", "42744166", "41532524", "42398657", "42341860", "42702174", "42876472", "42875898", "42860716", "42848519", "42835603", "42825377", "42787548", "42723442", "42679640", "42674238", "42641839", "42628218", "42616478", "42576420", "42574980", "42557222", "42550740", "42532324", "42509642", "42501831", "42464785", "42460995", "42449506", "42433082", "42421558", "42394524", "42391989", "42388227", "42339709", "42318678", "42311093", "42300690", "42274165", "42253188", "42209292", "42186437", "42048609", "41858052", "41846456", "41775345", "41742891", "41721713", "41709507", "41663214", "41601288", "41571448", "41566772", "41513586", "41498391", "41492104", "41481139", "41454575", "42660439", "42551717", "42648588", "42538607", "42431843", "42322011", "42276393", "42259422", "42176610", "42401341", "42815373", "42722218", "42540560", "42361483", "42140106", "42890799", "42871306", "42866245", "42864905", "42855213", "42855208", "42855207", "42855206", "42852635", "42840906", "42840437", "42835719", "42811483", "42777649", "42762965", "42761845", "42757455", "42751104", "42716462", "42715652", "42702203", "42692037", "42685927", "42685490", "42680813", "42668098", "42664864", "42662364", "42660345", "42648206", "42641315", "42640147", "42632483", "42632257", "42624032", "42623858", "42623505", "42618857", "42617478", "42612350", "42607381", "42606680", "42606023", "42604092", "42600902", "42583704", "42574910", "42546883", "42537713", "42526817", "42526771", "42521772", "42520374", "42501829", "42480805", "42460779", "42456992", "42448134", "42448060", "42437047", "42435230", "42430940", "42420696", "42402363", "42341192", "42335647", "42333995", "42320360", "42314511", "42307975", "42298759", "42250352", "42142768", "42142103", "42748573", "42722050", "42546913", "42219071", "42648821", "42893597" ], "http": 200 }, { "topic": "localized-colon", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND ((colon[tiab] OR colonic[tiab]) AND (adjuvant OR \"stage II\" OR \"stage III\" OR colectomy OR oxaliplatin OR IDEA OR MOSAIC)) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND ((\"colon\"[Title/Abstract] OR \"colonic\"[Title/Abstract]) AND (\"adjuvancy\"[All Fields] OR \"adjuvanted\"[All Fields] OR \"adjuvanting\"[All Fields] OR \"adjuvants\"[All Fields] OR \"adjuvants pharmaceutic\"[Pharmacological Action] OR \"adjuvants immunologic\"[Pharmacological Action] OR \"adjuvants pharmaceutic\"[Supplementary Concept] OR \"adjuvants pharmaceutic\"[All Fields] OR \"adjuvant\"[All Fields] OR \"adjuvants immunologic\"[Supplementary Concept] OR \"adjuvants immunologic\"[All Fields] OR \"adjuvants, pharmaceutic\"[MeSH Terms] OR (\"adjuvants\"[All Fields] AND \"pharmaceutic\"[All Fields]) OR \"pharmaceutic adjuvants\"[All Fields] OR \"adjuvants, immunologic\"[MeSH Terms] OR (\"adjuvants\"[All Fields] AND \"immunologic\"[All Fields]) OR \"immunologic adjuvants\"[All Fields] OR \"adjuvated\"[All Fields] OR \"adjuvation\"[All Fields] OR \"adjuvent\"[All Fields] OR \"stage II\"[All Fields] OR \"stage III\"[All Fields] OR (\"colectomy\"[MeSH Terms] OR \"colectomy\"[All Fields] OR \"colectomies\"[All Fields]) OR (\"oxaliplatin\"[Supplementary Concept] OR \"oxaliplatin\"[All Fields] OR \"oxaliplatin\"[MeSH Terms] OR \"oxaliplatine\"[All Fields] OR \"oxaliplatin s\"[All Fields]) OR (\"idea j law technol\"[Journal] OR \"idea\"[All Fields]) OR (\"mosaic\"[All Fields] OR \"mosaicism\"[MeSH Terms] OR \"mosaicism\"[All Fields] OR \"mosaicisms\"[All Fields] OR \"mosaics\"[All Fields]))) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 118, "ids": [ "42100890", "42859774", "42705597", "42662364", "42402363", "42893597", "42893802", "42892709", "42888104", "42885944", "42885719", "42885592", "42828282", "42743888", "42878713", "42874265", "42892179", "42860502", "42860475", "42850694", "42839242", "42831930", "42336324", "42823149", "42806446", "42780999", "42734427", "42648596", "42642672", "42600433", "42599639", "42557487", "42531715", "42526581", "42526157", "42502895", "42475760", "42468114", "42461618", "42447406", "42390664", "42360648", "42333415", "42247954", "42240880", "42217851", "42143413", "42095424", "42816637", "42813400", "42798120", "42788791", "42788424", "42786576", "42778688", "42768424", "42795017", "42770167", "42770054", "42754633", "42754357", "20301390", "42751096", "42745098", "42763649", "42755304", "42802880", "42736431", "42731437", "42798930", "42731431", "42722913", "42166219", "42738403", "42696661", "42791095", "42690265", "42684532", "42684439", "42684438", "42876137", "42803601", "42782872", "42755020", "42712998", "42699461", "42678889", "42662081", "42556946", "42462113", "42447830", "42443691", "42442073", "42440324", "42437336", "42402299", "42365160", "42334717", "42319590", "42318955", "42314799", "42265516", "42201415", "42189172", "42154247", "42142406", "42012676", "41964557", "41941600", "41869951", "41841469", "41217246", "42703468", "42682876", "42671704", "42331755", "42670380", "42661558" ], "http": 200 }, { "topic": "localized-rectal", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND ((rectal[tiab] OR rectum[tiab]) AND (TNT OR \"total neoadjuvant\" OR \"watch and wait\" OR \"watch-and-wait\" OR \"organ preservation\" OR RAPIDO OR OPRA OR chemoradiation OR TME)) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND ((\"rectal\"[Title/Abstract] OR \"rectum\"[Title/Abstract]) AND (\"trinitrotoluene\"[Supplementary Concept] OR \"trinitrotoluene\"[All Fields] OR \"tnt\"[All Fields] OR \"trinitrotoluene\"[MeSH Terms] OR \"total neoadjuvant\"[All Fields] OR \"watch-and-wait\"[All Fields] OR \"watch-and-wait\"[All Fields] OR \"organ preservation\"[All Fields] OR \"RAPIDO\"[All Fields] OR \"OPRA\"[All Fields] OR (\"chemoradiotherapy\"[MeSH Terms] OR \"chemoradiotherapy\"[All Fields] OR \"chemoradiation\"[All Fields]) OR (\"tumor microenviron\"[Journal] OR \"tme\"[All Fields]))) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 162, "ids": [ "41815020", "42835603", "42828123", "42787548", "41742891", "42889056", "42855207", "42843361", "42843360", "42843359", "42843358", "42733664", "42703503", "42604092", "42142768", "42142103", "42497379", "42497370", "42888297", "42743888", "42878066", "42855771", "42860519", "42860799", "42859999", "42859121", "42844118", "42479457", "41748160", "42874305", "42858628", "42837183", "42836881", "42830221", "42828530", "42889836", "42879159", "42879156", "42852907", "42834699", "42826364", "42822843", "42780999", "42758176", "42657816", "42645333", "42628250", "42604618", "42584749", "42551632", "42542012", "42531881", "42478479", "42350855", "42319589", "42258920", "42233285", "42178612", "42176680", "42067507", "41951767", "42816635", "42815616", "42813376", "42810789", "42810505", "42803842", "42799857", "42798965", "42789827", "42751528", "42881880", "42782287", "42776221", "42775551", "42771175", "42771174", "42795032", "42774732", "42767856", "42765418", "42772257", "42772256", "42777644", "42755064", "42755060", "42751329", "42747720", "42812258", "42746772", "42144888", "42734824", "42736779", "42717366", "42781368", "42780536", "42780443", "42407299", "42731501", "42712832", "42709377", "42704578", "42703166", "42832577", "42710280", "42696114", "42805858", "42755673", "42738373", "42699016", "42690486", "42685054", "42812498", "42789270", "42777177", "42692060", "42685802", "42674771", "42661270", "42633755", "42633754", "42582989", "42570607", "42569463", "42557488", "42556960", "42556957", "42553852", "42538775", "42521832", "42507974", "42495666", "42492015", "42473759", "42467205", "42435617", "42425831", "42402154", "42383070", "42383069", "42336700", "42321086", "42290893", "42290606", "42216999", "42201400", "42165392", "41936099", "41860709", "41801383", "41733646", "42703514", "42703456", "42703429", "42703411", "42682925", "42682693", "42671667", "42670628", "42691748", "42669333", "42729401" ], "http": 200 }, { "topic": "metastatic-systemic", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (metastatic AND (FOLFOXIRI OR FOLFOX OR FOLFIRI OR bevacizumab OR cetuximab OR panitumumab OR maintenance OR TRIBE OR chemotherapy)) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND ((\"metastatically\"[All Fields] OR \"metastatics\"[All Fields] OR \"metastatization\"[All Fields] OR \"metastatize\"[All Fields] OR \"metastatized\"[All Fields] OR \"metastatizing\"[All Fields] OR \"secondary\"[MeSH Subheading] OR \"secondary\"[All Fields] OR \"metastatic\"[All Fields]) AND (\"FOLFOXIRI\"[All Fields] OR \"FOLFOX\"[All Fields] OR \"FOLFIRI\"[All Fields] OR (\"bevacizumab\"[Supplementary Concept] OR \"bevacizumab\"[All Fields] OR \"bevacizumab\"[MeSH Terms] OR \"bevacizumab s\"[All Fields]) OR (\"cetuximab\"[Supplementary Concept] OR \"cetuximab\"[All Fields] OR \"cetuximab\"[MeSH Terms] OR \"cetuximab s\"[All Fields]) OR (\"panitumumab\"[Supplementary Concept] OR \"panitumumab\"[All Fields] OR \"panitumumab\"[MeSH Terms]) OR (\"maintenance\"[MeSH Terms] OR \"maintenance\"[All Fields] OR \"maintenances\"[All Fields]) OR (\"indigenous peoples\"[MeSH Terms] OR (\"indigenous\"[All Fields] AND \"peoples\"[All Fields]) OR \"indigenous peoples\"[All Fields] OR \"tribes\"[All Fields] OR \"tribe\"[All Fields] OR \"tribe s\"[All Fields]) OR (\"chemotherapy s\"[All Fields] OR \"drug therapy\"[MeSH Terms] OR (\"drug\"[All Fields] AND \"therapy\"[All Fields]) OR \"drug therapy\"[All Fields] OR \"chemotherapies\"[All Fields] OR \"drug therapy\"[MeSH Subheading] OR \"chemotherapy\"[All Fields]))) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 248, "ids": [ "42699228", "42322272", "42830811", "42787936", "42641839", "42509642", "42421558", "42311093", "41709507", "41601288", "42259422", "42836005", "42811483", "42801795", "42716462", "42648206", "42600902", "42594384", "42307975", "42142768", "42142103", "42891887", "42891583", "42888581", "42887494", "42885592", "42743888", "42743885", "42879043", "42878713", "42555229", "42272324", "42104745", "42837610", "42525921", "42852861", "42853287", "42850173", "42844118", "42861260", "42830449", "42834836", "42848681", "42830367", "42570380", "42190433", "42830873", "42826288", "42882865", "42831722", "42827381", "42823158", "42823153", "42823149", "42820775", "42798176", "42781069", "42780999", "42765734", "42703026", "42696650", "42648158", "42641427", "42634275", "42632353", "42622787", "42599639", "42587242", "42575055", "42562608", "42556459", "42537464", "42526707", "42526382", "42521522", "42502038", "42486946", "42480713", "42478487", "42478479", "42463606", "42462844", "42458924", "42455446", "42440027", "42385277", "42365544", "42360648", "42336066", "42289152", "42275677", "42258086", "42233285", "42229038", "42162286", "41397186", "41084117", "40643874", "40325930", "42837492", "42815004", "42814239", "42813376", "42811047", "42810750", "42865464", "42865424", "42250756", "42857020", "42789212", "42783246", "42835167", "42783922", "42766270", "41408490", "42859101", "42760712", "42668574", "42633244", "42824375", "42753826", "42752894", "42794953", "42744133", "42742862", "42742786", "42574031", "42424926", "42335543", "42769859", "42769799", "42807710", "42798938", "42731846", "42787239", "42741431", "42720875", "42456978", "42309466", "42860411", "42781368", "42780536", "42716685", "42616657", "42520593", "42456539", "42774118", "42710647", "42709325", "42704034", "42738403", "42701140", "42761260", "42696404", "42755449", "42738373", "42699016", "42687040", "42791169", "42704026", "42700475", "42686374", "42773727", "42768853", "42762518", "42755020", "42750628", "42750622", "42745771", "42745055", "42742942", "42729680", "42725237", "42723578", "42715502", "42710243", "42698582", "42688649", "42683320", "42678770", "42675036", "42674714", "42666074", "42665422", "42662081", "42661856", "42658767", "42636835", "42624041", "42617424", "42616591", "42612683", "42583256", "42583153", "42561547", "42545685", "42497817", "42492112", "42462456", "42437734" ], "http": 200 }, { "topic": "precision-immuno", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (KRAS OR BRAF OR HER2 OR NTRK OR immunotherapy OR pembrolizumab OR nivolumab OR dostarlimab OR sotorasib OR encorafenib OR checkpoint OR dMMR OR pMMR OR MSS) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"kras protein human\"[Supplementary Concept] OR \"kras protein human\"[All Fields] OR \"kras\"[All Fields] OR \"BRAF\"[All Fields] OR (\"erbb2 protein human\"[Supplementary Concept] OR \"erbb2 protein human\"[All Fields] OR \"her2\"[All Fields] OR \"erb b2 receptor tyrosine kinases\"[Supplementary Concept] OR \"erb b2 receptor tyrosine kinases\"[All Fields] OR \"erb b2 receptor tyrosine kinases\"[MeSH Terms] OR (\"erb b2\"[All Fields] AND \"receptor\"[All Fields] AND \"tyrosine\"[All Fields] AND \"kinases\"[All Fields])) OR \"NTRK\"[All Fields] OR (\"immunotherapy\"[MeSH Terms] OR \"immunotherapy\"[All Fields] OR \"immunotherapies\"[All Fields] OR \"immunotherapy s\"[All Fields]) OR (\"pembrolizumab\"[Supplementary Concept] OR \"pembrolizumab\"[All Fields]) OR (\"nivolumab\"[Supplementary Concept] OR \"nivolumab\"[All Fields] OR \"nivolumab\"[MeSH Terms] OR \"nivolumab s\"[All Fields]) OR (\"dostarlimab\"[Supplementary Concept] OR \"dostarlimab\"[All Fields]) OR (\"sotorasib\"[Supplementary Concept] OR \"sotorasib\"[All Fields]) OR (\"encorafenib\"[Supplementary Concept] OR \"encorafenib\"[All Fields]) OR (\"cell cycle checkpoints\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"cycle\"[All Fields] AND \"checkpoints\"[All Fields]) OR \"cell cycle checkpoints\"[All Fields] OR \"checkpoint\"[All Fields] OR \"checkpoints\"[All Fields]) OR \"dMMR\"[All Fields] OR \"pMMR\"[All Fields] OR \"MSS\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 539, "ids": [ "42685539", "42607643", "42419183", "42285341", "42689729", "42445966", "42424525", "42393838", "42381379", "42345355", "42322272", "42246276", "42212684", "42141809", "41981741", "41947036", "42702174", "42648057", "42892808", "42787936", "42787548", "42756777", "42668486", "42638413", "42616478", "42612398", "42576420", "42557222", "42550740", "42480340", "42391989", "42323914", "42311093", "42274165", "42229304", "41860356", "41742891", "41721713", "42538607", "42852635", "42835784", "42811483", "42757455", "42751104", "42733664", "42715652", "42695424", "42685927", "42680813", "42662364", "42632257", "42624032", "42612350", "42604092", "42603592", "42600902", "42574910", "42526817", "42476270", "42448134", "42437047", "42402363", "42372925", "42335647", "42307975", "42748573", "42546913", "42497379", "42497377", "42497370", "42892709", "42891583", "42891405", "42888581", "42887494", "42885719", "42835088", "42828282", "42879043", "42878900", "42876380", "42754466", "42525957", "42503264", "41672537", "42877983", "42875775", "42875546", "42874989", "42874557", "42873094", "42869393", "42815473", "42697201", "42875754", "42872124", "42869007", "42855771", "42879103", "42864387", "42863469", "42860233", "42580447", "42546912", "42526530", "42525921", "42871639", "42853888", "42842645", "42874514", "42848099", "42844247", "42844118", "42714955", "42882920", "42860120", "42847237", "42843574", "42842020", "42841377", "42830449", "41980760", "41748160", "42874305", "42840361", "42839060", "42839014", "42838996", "42837790", "42836935", "42714160", "42848681", "42833432", "42831658", "42830694", "42830389", "42830367", "42612269", "42551351", "42492133", "42880178", "42830873", "42829798", "42854555", "42829084", "42890735", "42890516", "42861819", "42828116", "42826902", "42461083", "42889067", "42882868", "42882865", "42882498", "42864774", "42859913", "42823185", "42823149", "42823087", "42822843", "42821536", "42820775", "42820689", "42820669", "42806446", "42803145", "42798176", "42781069", "42780999", "42758211", "42746058", "42741532", "42726205", "42703026", "42696829", "42641427", "42622787", "42618801", "42607848", "42599639", "42598205", "42595641", "42595201", "42594762", "42592954", "42587242", "42584749", "42556459", "42556129", "42552405", "42546403", "42541898", "42537464", "42531731", "42526707", "42526382", "42520384", "42508143", "42493268" ], "http": 200 }, { "topic": "liver-lung-mets", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"liver metastas*\" OR \"hepatic metastas*\" OR \"lung metastas*\" OR \"pulmonary metastas*\" OR CRLM OR ablation OR metastasectomy OR \"liver transplant*\" OR SBRT OR oligometastatic) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"liver metastas*\"[All Fields] OR \"hepatic metastas*\"[All Fields] OR \"lung metastas*\"[All Fields] OR \"pulmonary metastas*\"[All Fields] OR \"CRLM\"[All Fields] OR (\"ablate\"[All Fields] OR \"ablated\"[All Fields] OR \"ablates\"[All Fields] OR \"ablating\"[All Fields] OR \"ablation\"[All Fields] OR \"ablational\"[All Fields] OR \"ablations\"[All Fields]) OR (\"metastasectomy\"[MeSH Terms] OR \"metastasectomy\"[All Fields] OR \"metastasectomies\"[All Fields]) OR \"liver transplant*\"[All Fields] OR \"SBRT\"[All Fields] OR \"oligometastatic\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 234, "ids": [ "42860716", "42829779", "42641839", "42557222", "42311093", "41492104", "42259422", "42855213", "42835719", "42762965", "42731420", "42623858", "42606023", "42521772", "42480805", "42456992", "42435230", "42892521", "42880826", "42879043", "42217374", "42104745", "42874958", "42697201", "42869589", "42867594", "42864508", "42862093", "42860489", "42853879", "42879881", "42850173", "42850076", "42844247", "42844190", "42714955", "42844848", "42841921", "42837177", "42830367", "42830873", "42829798", "42826288", "42882865", "42827381", "42823165", "42823153", "42823149", "42820689", "42817716", "42781095", "42754631", "42730415", "42701958", "42686479", "42648158", "42642295", "42639425", "42636613", "42632353", "42623816", "42564636", "42561871", "42556459", "42542013", "42537464", "42533302", "42531781", "42521522", "42502090", "42502038", "42477180", "42473131", "42463606", "42463528", "42462844", "42413310", "42385277", "42384210", "42379517", "42365544", "42360648", "42289152", "42258086", "42229038", "42219691", "42162286", "42154581", "41963636", "41949118", "41746604", "41650980", "41250835", "20301428", "42876547", "42870802", "42814474", "42811485", "42866402", "42865464", "42802203", "42250756", "42217558", "42882823", "42849331", "42799748", "42884295", "42881061", "42857020", "42856582", "42882800", "42783246", "42837725", "42778117", "42777749", "42882775", "42882765", "42772510", "42768024", "42802120", "42794818", "42795010", "42777678", "42762973", "42760391", "42759107", "42733865", "42668654", "42824375", "42754214", "42753826", "42891465", "42819295", "42794959", "42749975", "42812292", "42812236", "42794943", "42763649", "42743054", "42335543", "42795613", "42731467", "42731846", "42726122", "42787239", "42717115", "42623604", "42794885", "42781368", "42520593", "42851973", "42705921", "42769402", "42705546", "42704036", "42761260", "42710253", "42755638", "42739818", "42686374", "42876137", "42757969", "42750625", "42745771", "42745364", "42725237", "42717494", "42699925", "42682916", "42674686", "42674684", "42671412", "42668726", "42665422", "42661856", "42658767", "42624041", "42561547", "42557330", "42552285", "42547745", "42543402", "42494952", "42463524", "42462456", "42458165", "42435654", "42411783", "42397676", "42392452", "42378631", "42372602", "42365160", "42336136", "42314798", "42314058", "42312562", "42308639", "42307850" ], "http": 200 }, { "topic": "ctdna-biomarkers", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (ctDNA OR \"circulating tumor DNA\" OR \"liquid biopsy\" OR \"minimal residual\" OR \"molecular residual\" OR CEA[tiab]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"ctdna\"[All Fields] OR \"ctdnas\"[All Fields] OR \"circulating tumor DNA\"[All Fields] OR \"liquid biopsy\"[All Fields] OR \"minimal residual\"[All Fields] OR \"molecular residual\"[All Fields] OR \"CEA\"[Title/Abstract]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 145, "ids": [ "42392486", "42391702", "42320666", "42285341", "42848519", "42830887", "42787936", "42464785", "41764032", "42855208", "42827738", "42574910", "42435230", "42402363", "42891887", "42888297", "42887741", "42886530", "42885719", "42823331", "42879043", "42878949", "42876326", "42877983", "42858627", "42567577", "42843562", "42841257", "42789753", "42843093", "42834664", "42843135", "42828116", "42827107", "42889832", "42882868", "42861220", "42826364", "42823153", "42822680", "42758211", "42692772", "42622787", "42619242", "42618801", "42607848", "42594762", "42575055", "42556459", "42468317", "42462844", "42448198", "42384210", "42336066", "42268308", "42258920", "42165364", "42095424", "41963636", "41543944", "41397186", "42870803", "42837492", "42882848", "42882841", "42791456", "42786576", "42793206", "42795017", "42777678", "42772256", "42762231", "42835715", "42758189", "42633244", "42770354", "42891465", "42749910", "42748384", "42745098", "42763649", "42745504", "42574031", "42802880", "42769799", "42736431", "42794922", "30335319", "42798930", "42795834", "42794507", "42794907", "42736686", "42731431", "42781368", "42616657", "42705926", "42832577", "42761024", "42690333", "42808411", "42723578", "42689616", "42685313", "42678463", "42668443", "42661856", "42640608", "42627151", "42598790", "42582989", "42523055", "42495661", "42437734", "42397676", "42383069", "42378815", "42362879", "42335576", "42334717", "42333742", "42331068", "42312562", "42274209", "42265516", "42250735", "42225541", "42153641", "42144080", "41329990", "42724862", "42724860", "42724425", "42707883", "42703488", "42703482", "42703453", "42703440", "42703312", "42331755", "42669322", "42802819", "42729463", "42729228", "42663748" ], "http": 200 }, { "topic": "survivorship", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (survivorship OR LARS OR neuropathy OR stoma OR ostomy OR \"quality of life\" OR sexual OR fertility OR \"financial toxicity\" OR late-effect*) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"survivorship\"[MeSH Terms] OR \"survivorship\"[All Fields] OR \"survivorships\"[All Fields] OR \"LARS\"[All Fields] OR (\"neuropathies\"[All Fields] OR \"neuropathy\"[All Fields]) OR (\"surgical stomas\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"stomas\"[All Fields]) OR \"surgical stomas\"[All Fields] OR \"stoma\"[All Fields] OR \"stomas\"[All Fields]) OR (\"ostomy\"[MeSH Terms] OR \"ostomy\"[All Fields] OR \"ostomies\"[All Fields]) OR \"quality of life\"[All Fields] OR (\"sexual behavior\"[MeSH Terms] OR (\"sexual\"[All Fields] AND \"behavior\"[All Fields]) OR \"sexual behavior\"[All Fields] OR \"sexual\"[All Fields] OR \"sexually\"[All Fields] OR \"sexualities\"[All Fields] OR \"sexuality\"[MeSH Terms] OR \"sexuality\"[All Fields] OR \"sexualization\"[All Fields] OR \"sexualize\"[All Fields] OR \"sexualized\"[All Fields] OR \"sexualizing\"[All Fields] OR \"sexuals\"[All Fields]) OR (\"fertiles\"[All Fields] OR \"fertility\"[MeSH Terms] OR \"fertility\"[All Fields] OR \"fertile\"[All Fields] OR \"fertilities\"[All Fields]) OR \"financial toxicity\"[All Fields] OR \"late effect*\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 211, "ids": [ "42700497", "42832379", "42787548", "42508240", "42388227", "42358730", "42253417", "42253415", "42037577", "41858760", "41852759", "41742891", "41732288", "41571448", "42322026", "42843361", "42801795", "42763522", "42733664", "42716462", "42685390", "42681563", "42664864", "42888581", "42743885", "42878900", "42875946", "42875765", "42874631", "42873277", "42867138", "42860497", "42859121", "42858024", "42855709", "42855147", "42853669", "42853291", "42850173", "42844118", "42846546", "42842497", "42838997", "42837183", "42836881", "42831906", "42880173", "42830221", "42829933", "42882890", "42828530", "42879159", "42879156", "42831722", "42826364", "42761516", "42696829", "42617376", "42604618", "42572962", "42504777", "42495836", "42480713", "42424767", "42323128", "42319589", "42268425", "42249907", "42246981", "42187338", "42178612", "42060079", "42032897", "40168548", "20301428", "42816637", "42816498", "42815287", "42810789", "42810505", "42808962", "42826543", "42812216", "42804968", "42798965", "42791407", "42790904", "42789150", "42788290", "42751528", "42881880", "42786453", "42782344", "42782287", "42778470", "42775551", "42775537", "42840307", "42772330", "42770946", "42770376", "42835228", "42795032", "42766098", "42765418", "42764589", "42777644", "42760712", "42759107", "42755298", "42794988", "42754273", "42748022", "20301390", "42749910", "42795916", "42755304", "42742505", "41992467", "42822862", "42753512", "42731930", "42787091", "42782893", "42731507", "42731506", "42729095", "42722914", "42717059", "42780712", "42780536", "42166219", "42153532", "42712832", "42769805", "42704598", "42700430", "42814593", "42765566", "42710253", "42755857", "42693363", "42811288", "42876137", "42789270", "42769661", "42750628", "42745369", "42745364", "42736922", "42717759", "42699857", "42698582", "42691897", "42685802", "42683498", "42675856", "42675821", "42665960", "42637888", "42633754", "42612278", "42600448", "42583256", "42583153", "42557488", "42556070", "42553907", "42553852", "42553833", "42538213", "42495657", "42473772", "42435525", "42435282", "42420493", "42405505", "42385137", "42383070", "42367062", "42324023", "42321086", "42318955", "42310267", "42290606", "42285832", "42274335", "42264069", "42263810", "42263793", "42213352", "42165854", "42165233", "42154247", "41966460", "41891935", "41816867", "41814098", "41805457", "41633356" ], "http": 200 }, { "topic": "safety-complications", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (obstruction OR perforation OR toxicity OR DPYD OR UGT1A1 OR \"anastomotic leak\" OR sepsis OR bleeding OR irinotecan) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"obstruct\"[All Fields] OR \"obstructed\"[All Fields] OR \"obstructing\"[All Fields] OR \"obstruction\"[All Fields] OR \"obstructions\"[All Fields] OR \"obstructive\"[All Fields] OR \"obstructs\"[All Fields] OR (\"perforant\"[All Fields] OR \"perforants\"[All Fields] OR \"perforate\"[All Fields] OR \"perforated\"[All Fields] OR \"perforates\"[All Fields] OR \"perforating\"[All Fields] OR \"perforation\"[All Fields] OR \"perforations\"[All Fields] OR \"perforative\"[All Fields] OR \"perforator\"[All Fields] OR \"perforator s\"[All Fields] OR \"perforators\"[All Fields]) OR (\"toxic\"[All Fields] OR \"toxical\"[All Fields] OR \"toxically\"[All Fields] OR \"toxicant\"[All Fields] OR \"toxicant s\"[All Fields] OR \"toxicants\"[All Fields] OR \"toxicated\"[All Fields] OR \"toxication\"[All Fields] OR \"toxicities\"[All Fields] OR \"toxicity\"[MeSH Subheading] OR \"toxicity\"[All Fields] OR \"toxicity s\"[All Fields] OR \"toxics\"[All Fields]) OR (\"dpyd protein human\"[Supplementary Concept] OR \"dpyd protein human\"[All Fields] OR \"dpyd\"[All Fields]) OR \"UGT1A1\"[All Fields] OR \"anastomotic leak\"[All Fields] OR (\"sepsis\"[MeSH Terms] OR \"sepsis\"[All Fields]) OR (\"bleedings\"[All Fields] OR \"hemorrhage\"[MeSH Terms] OR \"hemorrhage\"[All Fields] OR \"bleed\"[All Fields] OR \"bleeding\"[All Fields] OR \"bleeds\"[All Fields]) OR (\"irinotecan\"[Supplementary Concept] OR \"irinotecan\"[All Fields] OR \"irinotecan\"[MeSH Terms] OR \"irinotecan s\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 422, "ids": [ "42781356", "42685539", "42751510", "42722114", "42546541", "42859774", "42835091", "42830811", "42829779", "42781465", "42756777", "42612398", "42540399", "42501831", "42421558", "42209292", "41858760", "41709507", "41566772", "41498391", "41492998", "41052213", "42660439", "42785529", "42871306", "42840437", "42835719", "42811483", "42801795", "42763522", "42741551", "42716462", "42703503", "42681563", "42664864", "42648206", "42612350", "42607381", "42556653", "42476270", "42448060", "42402363", "42366498", "42307975", "42722050", "42893597", "42892709", "42888581", "42886614", "42886280", "42743888", "42743885", "42891491", "42754466", "42748746", "42731188", "42263581", "42875765", "42874443", "42873094", "42872459", "42892166", "42403340", "42862080", "42861621", "42860233", "42580447", "42871639", "42850694", "42879881", "42850173", "42629258", "42844369", "42843801", "42843601", "42842497", "42830449", "42839587", "42839549", "42839242", "42837296", "42834333", "42832380", "42831658", "42570380", "42190433", "42835528", "42830221", "42829798", "42883298", "42890735", "42872048", "42827216", "42827031", "42826902", "42882868", "42866725", "42859914", "42859913", "42858313", "42857436", "42851126", "42842389", "42839779", "42834699", "42823835", "42823533", "42821563", "42821450", "42821154", "42820775", "42820689", "42781095", "42781041", "42780999", "42780459", "42772305", "42765734", "42762577", "42734427", "42705103", "42696650", "42647025", "42632353", "42627631", "42624235", "42617376", "42605598", "42595201", "42572962", "42556129", "42555992", "42551632", "42551539", "42547030", "42531781", "42530560", "42503157", "42493617", "42478487", "42467218", "42463606", "42462844", "42462747", "42461618", "42455446", "42448198", "42447406", "42425352", "42398580", "42390664", "42364787", "42340642", "42333415", "42328851", "42323128", "42315073", "42314698", "42310825", "42289636", "42263871", "42247954", "42246981", "42228134", "42217851", "42190419", "42185682", "42105183", "42095296", "42081185", "42065991", "42060079", "42017488", "41958031", "41956148", "41935860", "41931969", "41895479", "41672479", "41084117", "40325930", "20301428", "42876623", "42854553", "42837715", "42816637", "42813376", "42707789", "42882474", "42811046", "42810789", "42810750", "42826543", "42804968", "42804071", "42263836", "42250753", "42217558", "42882823", "42803243" ], "http": 200 }, { "topic": "guidelines", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"Practice Guideline\"[pt] OR \"Guideline\"[pt] OR \"Consensus Development Conference\"[pt] OR guideline[ti] OR \"clinical practice guideline\"[tiab] OR \"consensus statement\"[tiab]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"Practice Guideline\"[Publication Type] OR \"Guideline\"[Publication Type] OR \"Guideline\"[Title] OR \"clinical practice guideline\"[Title/Abstract] OR \"consensus statement\"[Title/Abstract]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 17, "ids": [ "42711590", "42604010", "42364818", "41895479", "41385753", "42814894", "42814066", "42814045", "42771175", "42831105", "42599724", "41770836", "42731257", "42656090", "42684532", "42683623", "42389808" ], "http": 200 }, { "topic": "entrez-since-2026-10-12", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"2026/10/12\"[Date - Entrez] : \"3000\"[Date - Entrez])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND 2026/10/12:3000/12/31[Date - Entry]", "count": 311, "ids": [ "42867783", "42892808", "42876472", "42875898", "42860716", "42889706", "42890799", "42889056", "42888865", "42871306", "42866245", "42864905", "42893597", "42893802", "42893509", "42893504", "42893452", "42892709", "42892521", "42892442", "42891902", "42891887", "42891705", "42892687", "42892101", "42891625", "42891583", "42891405", "42891063", "42890059", "42888642", "42888599", "42888581", "42888568", "42888372", "42888297", "42888104", "42887741", "42887539", "42887538", "42887494", "42887152", "42887063", "42886720", "42886614", "42886590", "42886530", "42886436", "42886393", "42886280", "42886270", "42886269", "42885944", "42885807", "42885719", "42885592", "42892154", "42891491", "42890343", "42887457", "42887343", "42886465", "42881315", "42881313", "42880826", "42880456", "42880254", "42879954", "42879502", "42879326", "42879114", "42879099", "42879043", "42879037", "42878975", "42878963", "42878949", "42878900", "42878713", "42878066", "42876380", "42876326", "42892246", "42887195", "42877983", "42877795", "42877644", "42877611", "42875946", "42875775", "42875765", "42875698", "42875650", "42875546", "42875341", "42874991", "42874989", "42874958", "42874631", "42874562", "42874557", "42874443", "42874265", "42873913", "42873277", "42873094", "42872622", "42872459", "42870741", "42870672", "42870433", "42869393", "42892179", "42892166", "42892023", "42889995", "42885270", "42879982", "42879957", "42875754", "42872124", "42871678", "42870218", "42869589", "42869126", "42869123", "42869113", "42869007", "42868715", "42868089", "42867948", "42867691", "42867594", "42867417", "42867251", "42867167", "42867161", "42867138", "42865227", "42865226", "42864508", "42879642", "42879103", "42874270", "42870228", "42864967", "42864471", "42864387", "42864133", "42863976", "42863580", "42863469", "42863462", "42862502", "42862093", "42862080", "42861870", "42861640", "42861621", "42861616", "42861572", "42861489", "42860519", "42860502", "42860489", "42860475", "42860445", "42887074", "42868791", "42860799", "42860497", "42879989", "42872031", "42871639", "42884177", "42883336", "42882925", "42879881", "42874514", "42874308", "42871149", "42882920", "42882519", "42868808", "42863223", "42861260", "42888406", "42884735", "42874305", "42868947", "42880178", "42880173", "42868954", "42884079", "42883639", "42883298", "42882890", "42890735", "42890536", "42890516" ], "http": 200 }, { "topic": "rct", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"Randomized Controlled Trial\"[pt] OR randomized[ti] OR randomised[ti]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"Randomized Controlled Trial\"[Publication Type] OR \"randomized\"[Title] OR \"randomised\"[Title]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 92, "ids": [ "42840411", "42829779", "42723442", "42421558", "42142768", "42142103", "42892687", "42743888", "42743885", "42891491", "42555229", "42875765", "42873277", "42525921", "42884177", "42871149", "42850173", "42861260", "42830449", "42838765", "42832110", "41334638", "42841450", "42722889", "42647025", "42600427", "42575283", "42572962", "42570350", "42547360", "42502090", "42463528", "42462747", "42461618", "42365851", "42331035", "42246495", "42070696", "42065991", "42060079", "42009205", "41935575", "42816498", "42791407", "42790919", "42785338", "42778806", "42778242", "42777749", "42795032", "42767745", "42859101", "42760086", "42748427", "42745051", "42731846", "42520593", "42166219", "42700222", "42782000", "42765562", "42725584", "42693109", "42644818", "42684438", "42755020", "42686507", "42678457", "42675036", "42666074", "42636835", "42633754", "42583256", "42581199", "42545685", "42507974", "42492015", "42472638", "42435525", "42425127", "42290606", "42249259", "42228944", "42217757", "42173791", "42012787", "41841469", "41816867", "41611967", "41610931", "41510976", "39964165" ], "http": 200 }, { "topic": "systematic-review", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"Systematic Review\"[pt] OR \"Meta-Analysis\"[pt] OR \"systematic review\"[ti] OR meta-analysis[ti]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"Systematic Review\"[Publication Type] OR \"meta analysis\"[Publication Type] OR \"Systematic Review\"[Title] OR \"meta analysis\"[Title]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 137, "ids": [ "42037577", "41454717", "42827738", "42801795", "42692037", "42685390", "42681563", "42660345", "42641254", "42460779", "42402363", "42053092", "42891887", "42891583", "42891491", "42880456", "42875341", "42865226", "42882920", "42844510", "42858628", "42837183", "42833723", "42832233", "42890516", "42834699", "42833996", "42811387", "42754631", "42617376", "42600473", "42600433", "42600427", "42594997", "42574955", "42547360", "42492394", "42463606", "42463528", "42435723", "42364818", "42323128", "42275677", "42213274", "42178612", "42151665", "42143914", "41973375", "41784442", "41677135", "41397186", "42876623", "42816637", "42816164", "42814239", "42815287", "42808962", "42865424", "42804968", "42881061", "42790910", "42851468", "42778806", "42776379", "42775560", "42772509", "42770376", "42662600", "42745098", "42744960", "42743896", "42769859", "42728437", "42726123", "42722914", "42780443", "42780397", "42716253", "42714744", "42714662", "42714641", "42714031", "42704578", "42704036", "42703166", "42738783", "42700272", "42832577", "42765566", "42765562", "42725584", "42755779", "42755673", "42687040", "42811288", "42684532", "42769661", "42725237", "42717759", "42684859", "42668443", "42665960", "42581199", "42557488", "42547638", "42546905", "42526271", "42497817", "42495671", "42437515", "42435617", "42401231", "42361054", "42336601", "42310252", "42306995", "42296400", "42265335", "42263810", "42236440", "42124347", "42084721", "41934582", "41932450", "41902996", "41841469", "41721867", "41604561", "40062923", "42788453", "42724722", "42703460", "42703453", "42699804", "42692412", "42675353", "42669322" ], "http": 200 }, { "topic": "guideline-pt", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"Practice Guideline\"[pt] OR \"Guideline\"[pt]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"Practice Guideline\"[Publication Type] OR \"Guideline\"[Publication Type]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 5, "ids": [ "42364818", "42814066", "42814045", "42683623", "42389808" ], "http": 200 }, { "topic": "high-impact", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"N Engl J Med\"[jour] OR \"Lancet\"[jour] OR \"Lancet Oncol\"[jour] OR \"JAMA\"[jour] OR \"J Clin Oncol\"[jour] OR \"Ann Oncol\"[jour] OR \"Nat Med\"[jour] OR \"Gut\"[jour] OR \"Gastroenterology\"[jour] OR \"CA Cancer J Clin\"[jour] OR \"Lancet Gastroenterol Hepatol\"[jour]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"N Engl J Med\"[Journal] OR \"Lancet\"[Journal] OR \"Lancet Oncol\"[Journal] OR \"JAMA\"[Journal] OR \"J Clin Oncol\"[Journal] OR \"Ann Oncol\"[Journal] OR \"Nat Med\"[Journal] OR \"Gut\"[Journal] OR \"Gastroenterology\"[Journal] OR \"CA Cancer J Clin\"[Journal] OR \"Lancet Gastroenterol Hepatol\"[Journal]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 62, "ids": [ "42843361", "42843360", "42843359", "42843358", "42692037", "42497379", "42497377", "42497370", "42823331", "42863976", "42849474", "42849473", "42849472", "42849471", "42550992", "42525921", "42843898", "42843562", "41980760", "41791848", "41748160", "41629149", "40681325", "42696295", "42722889", "42575120", "42575119", "42462747", "42142544", "42070696", "42816155", "42814045", "42789827", "42785338", "42777749", "42748438", "42748437", "42748427", "42748384", "42742497", "42574033", "42574031", "42574029", "42574027", "42574019", "42728028", "42599724", "41770836", "41314787", "42692118", "42831778", "42745055", "42636835", "42633755", "42633754", "42545706", "42545685", "42507974", "42492015", "42425127", "42142622", "41932450" ], "http": 200 }, { "topic": "retraction", "cochrane": false, "query": "(\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"Retracted Publication\"[pt] OR \"Retraction of Publication\"[pt] OR \"Expression of Concern\"[pt]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "(\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND (\"Retracted Publication\"[Publication Type] OR \"Expression of Concern\"[Publication Type]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 3, "ids": [ "42825377", "42844080", "42865666" ], "http": 200 }, { "topic": "followup-uids", "cochrane": false, "query": "42748427[uid] OR 42777749[uid] OR 42770376[uid] OR 42745098[uid] OR 42829779[uid] OR 42417444[uid] OR 42683623[uid] OR 42814045[uid] OR 41990853[uid] OR 41741110[uid] OR 42200680[uid]", "translation": "42748427[UID] OR 42777749[UID] OR 42770376[UID] OR 42745098[UID] OR 42829779[UID] OR 42417444[UID] OR 42683623[UID] OR 42814045[UID] OR 41990853[UID] OR 41741110[UID] OR 42200680[UID]", "count": 11, "ids": [ "42829779", "42814045", "42777749", "42770376", "42748427", "42745098", "42683623", "42417444", "41990853", "42200680", "41741110" ], "http": 200 } ], "cochrane": [ { "topic": "cochrane-crc-broad", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (\"Colorectal Neoplasms\"[Mesh] OR \"colorectal cancer\"[tiab] OR \"colorectal adenocarcinoma\"[tiab] OR \"colon cancer\"[tiab] OR \"rectal cancer\"[tiab] OR \"colorectal carcinoma\"[tiab]) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"Colorectal Neoplasms\"[MeSH Terms] OR \"colorectal cancer\"[Title/Abstract] OR \"colorectal adenocarcinoma\"[Title/Abstract] OR \"colon cancer\"[Title/Abstract] OR \"rectal cancer\"[Title/Abstract] OR \"colorectal carcinoma\"[Title/Abstract]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 1, "ids": [ "42770376" ], "http": 200 }, { "topic": "cochrane-screening", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (screening OR FIT OR colonoscopy OR sigmoidoscopy) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"diagnosis\"[MeSH Subheading] OR \"diagnosis\"[All Fields] OR \"screening\"[All Fields] OR \"mass screening\"[MeSH Terms] OR (\"mass\"[All Fields] AND \"screening\"[All Fields]) OR \"mass screening\"[All Fields] OR \"early detection of cancer\"[MeSH Terms] OR (\"early\"[All Fields] AND \"detection\"[All Fields] AND \"cancer\"[All Fields]) OR \"early detection of cancer\"[All Fields] OR \"screen\"[All Fields] OR \"screenings\"[All Fields] OR \"screened\"[All Fields] OR \"screens\"[All Fields] OR (\"seizures\"[MeSH Terms] OR \"seizures\"[All Fields] OR \"fit\"[All Fields]) OR (\"colonoscopy\"[MeSH Terms] OR \"colonoscopy\"[All Fields] OR \"colonoscopies\"[All Fields]) OR (\"sigmoidoscopy\"[MeSH Terms] OR \"sigmoidoscopy\"[All Fields] OR \"sigmoidoscopies\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 8, "ids": [ "42852683", "42849912", "42836368", "42781846", "42765455", "42765454", "42713886", "42677895" ], "http": 200 }, { "topic": "cochrane-adjuvant", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (adjuvant OR oxaliplatin OR chemotherapy) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"adjuvancy\"[All Fields] OR \"adjuvanted\"[All Fields] OR \"adjuvanting\"[All Fields] OR \"adjuvants\"[All Fields] OR \"adjuvants pharmaceutic\"[Pharmacological Action] OR \"adjuvants immunologic\"[Pharmacological Action] OR \"adjuvants pharmaceutic\"[Supplementary Concept] OR \"adjuvants pharmaceutic\"[All Fields] OR \"adjuvant\"[All Fields] OR \"adjuvants immunologic\"[Supplementary Concept] OR \"adjuvants immunologic\"[All Fields] OR \"adjuvants, pharmaceutic\"[MeSH Terms] OR (\"adjuvants\"[All Fields] AND \"pharmaceutic\"[All Fields]) OR \"pharmaceutic adjuvants\"[All Fields] OR \"adjuvants, immunologic\"[MeSH Terms] OR (\"adjuvants\"[All Fields] AND \"immunologic\"[All Fields]) OR \"immunologic adjuvants\"[All Fields] OR \"adjuvated\"[All Fields] OR \"adjuvation\"[All Fields] OR \"adjuvent\"[All Fields] OR (\"oxaliplatin\"[Supplementary Concept] OR \"oxaliplatin\"[All Fields] OR \"oxaliplatin\"[MeSH Terms] OR \"oxaliplatine\"[All Fields] OR \"oxaliplatin s\"[All Fields]) OR (\"chemotherapy s\"[All Fields] OR \"drug therapy\"[MeSH Terms] OR (\"drug\"[All Fields] AND \"therapy\"[All Fields]) OR \"drug therapy\"[All Fields] OR \"chemotherapies\"[All Fields] OR \"drug therapy\"[MeSH Subheading] OR \"chemotherapy\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 21, "ids": [ "42863850", "42861682", "42849912", "42841340", "42813499", "42813456", "42813446", "42803656", "42788405", "42781843", "42775611", "42770374", "42765455", "42757711", "42746927", "42746925", "42741999", "42713852", "42695385", "42695376", "42677885" ], "http": 200 }, { "topic": "cochrane-rectal", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (rectal OR TNT OR \"organ preservation\" OR radiotherapy) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"administration, rectal\"[MeSH Terms] OR (\"administration\"[All Fields] AND \"rectal\"[All Fields]) OR \"rectal administration\"[All Fields] OR \"rectal\"[All Fields] OR (\"trinitrotoluene\"[Supplementary Concept] OR \"trinitrotoluene\"[All Fields] OR \"tnt\"[All Fields] OR \"trinitrotoluene\"[MeSH Terms]) OR \"organ preservation\"[All Fields] OR (\"radiotherapy\"[MeSH Terms] OR \"radiotherapy\"[All Fields] OR \"radiotherapies\"[All Fields] OR \"radiotherapy\"[MeSH Subheading] OR \"radiotherapy s\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 2, "ids": [ "42770376", "42713842" ], "http": 200 }, { "topic": "cochrane-metastatic", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (metastatic OR bevacizumab OR cetuximab OR immunotherapy) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"metastatically\"[All Fields] OR \"metastatics\"[All Fields] OR \"metastatization\"[All Fields] OR \"metastatize\"[All Fields] OR \"metastatized\"[All Fields] OR \"metastatizing\"[All Fields] OR \"secondary\"[MeSH Subheading] OR \"secondary\"[All Fields] OR \"metastatic\"[All Fields] OR (\"bevacizumab\"[Supplementary Concept] OR \"bevacizumab\"[All Fields] OR \"bevacizumab\"[MeSH Terms] OR \"bevacizumab s\"[All Fields]) OR (\"cetuximab\"[Supplementary Concept] OR \"cetuximab\"[All Fields] OR \"cetuximab\"[MeSH Terms] OR \"cetuximab s\"[All Fields]) OR (\"immunotherapy\"[MeSH Terms] OR \"immunotherapy\"[All Fields] OR \"immunotherapies\"[All Fields] OR \"immunotherapy s\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 18, "ids": [ "42886005", "42886002", "42861682", "42852683", "42836368", "42803656", "42781846", "42765455", "42757711", "42757654", "42754260", "42746925", "42746921", "42746920", "42742038", "42742033", "42713886", "42689525" ], "http": 200 }, { "topic": "cochrane-liver", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (liver OR ablation OR metastasectomy OR hepatic) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"liver\"[MeSH Terms] OR \"liver\"[All Fields] OR \"livers\"[All Fields] OR \"liver s\"[All Fields] OR (\"ablate\"[All Fields] OR \"ablated\"[All Fields] OR \"ablates\"[All Fields] OR \"ablating\"[All Fields] OR \"ablation\"[All Fields] OR \"ablational\"[All Fields] OR \"ablations\"[All Fields]) OR (\"metastasectomy\"[MeSH Terms] OR \"metastasectomy\"[All Fields] OR \"metastasectomies\"[All Fields]) OR (\"hepatic\"[All Fields] OR \"hepatophyta\"[MeSH Terms] OR \"hepatophyta\"[All Fields] OR \"hepatics\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 4, "ids": [ "42770372", "42757711", "42713852", "42713842" ], "http": 200 }, { "topic": "cochrane-ctdna", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (ctDNA OR \"circulating tumor DNA\" OR \"liquid biopsy\") AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"ctdna\"[All Fields] OR \"ctdnas\"[All Fields] OR \"circulating tumor DNA\"[All Fields] OR \"liquid biopsy\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 0, "ids": [], "http": 200 }, { "topic": "cochrane-serrated", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (serrated OR adenoma OR polypectomy OR surveillance) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"serrate\"[All Fields] OR \"serrated\"[All Fields] OR \"serration\"[All Fields] OR \"serrations\"[All Fields] OR (\"adenoma\"[MeSH Terms] OR \"adenoma\"[All Fields] OR \"adenomas\"[All Fields] OR \"adenoma s\"[All Fields]) OR (\"polypectomies\"[All Fields] OR \"polypectomy\"[All Fields]) OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"surveillance\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"surveilance\"[All Fields] OR \"surveillances\"[All Fields] OR \"surveilled\"[All Fields] OR \"surveillence\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 19, "ids": [ "42867023", "42861682", "42861678", "42841340", "42788405", "42781846", "42775611", "42770376", "42770372", "42765454", "42754260", "42742033", "42741999", "42713852", "42695385", "42695349", "42689503", "42680183", "42677895" ], "http": 200 }, { "topic": "cochrane-hereditary", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (Lynch OR polyposis OR hereditary) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"lynch\"[All Fields] OR \"lynch s\"[All Fields] OR \"polyposis\"[All Fields] OR \"hereditary\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 0, "ids": [], "http": 200 }, { "topic": "cochrane-survivorship", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (survivorship OR LARS OR stoma OR quality of life) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"survivorship\"[MeSH Terms] OR \"survivorship\"[All Fields] OR \"survivorships\"[All Fields] OR \"LARS\"[All Fields] OR (\"surgical stomas\"[MeSH Terms] OR (\"surgical\"[All Fields] AND \"stomas\"[All Fields]) OR \"surgical stomas\"[All Fields] OR \"stoma\"[All Fields] OR \"stomas\"[All Fields]) OR (\"quality of life\"[MeSH Terms] OR (\"quality\"[All Fields] AND \"life\"[All Fields]) OR \"quality of life\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 16, "ids": [ "42886005", "42867023", "42863850", "42841340", "42781846", "42770376", "42770372", "42757634", "42754260", "42746927", "42741999", "42720098", "42713852", "42713842", "42680183", "42663176" ], "http": 200 }, { "topic": "cochrane-surgery", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (colectomy OR anastomosis OR \"transanal tube\" OR laparoscopic) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"colectomy\"[MeSH Terms] OR \"colectomy\"[All Fields] OR \"colectomies\"[All Fields] OR (\"anastomosis, surgical\"[MeSH Terms] OR (\"anastomosis\"[All Fields] AND \"surgical\"[All Fields]) OR \"surgical anastomosis\"[All Fields] OR \"anastomosis\"[All Fields]) OR \"transanal tube\"[All Fields] OR (\"laparoscopes\"[MeSH Terms] OR \"laparoscopes\"[All Fields] OR \"laparoscope\"[All Fields] OR \"laparoscopical\"[All Fields] OR \"laparoscopically\"[All Fields] OR \"laparoscopics\"[All Fields] OR \"laparoscopy\"[MeSH Terms] OR \"laparoscopy\"[All Fields] OR \"laparoscopic\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 2, "ids": [ "42770376", "42770372" ], "http": 200 }, { "topic": "cochrane-immuno", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (immunotherapy OR pembrolizumab OR checkpoint OR MSI OR dMMR) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"immunotherapy\"[MeSH Terms] OR \"immunotherapy\"[All Fields] OR \"immunotherapies\"[All Fields] OR \"immunotherapy s\"[All Fields] OR (\"pembrolizumab\"[Supplementary Concept] OR \"pembrolizumab\"[All Fields]) OR (\"cell cycle checkpoints\"[MeSH Terms] OR (\"cell\"[All Fields] AND \"cycle\"[All Fields] AND \"checkpoints\"[All Fields]) OR \"cell cycle checkpoints\"[All Fields] OR \"checkpoint\"[All Fields] OR \"checkpoints\"[All Fields]) OR \"MSI\"[All Fields] OR \"dMMR\"[All Fields]) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 0, "ids": [], "http": 200 }, { "topic": "cochrane-safety", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (obstruction OR stent OR perforation OR toxicity) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"obstruct\"[All Fields] OR \"obstructed\"[All Fields] OR \"obstructing\"[All Fields] OR \"obstruction\"[All Fields] OR \"obstructions\"[All Fields] OR \"obstructive\"[All Fields] OR \"obstructs\"[All Fields] OR (\"stent s\"[All Fields] OR \"stentings\"[All Fields] OR \"stents\"[MeSH Terms] OR \"stents\"[All Fields] OR \"stent\"[All Fields] OR \"stented\"[All Fields] OR \"stenting\"[All Fields]) OR (\"perforant\"[All Fields] OR \"perforants\"[All Fields] OR \"perforate\"[All Fields] OR \"perforated\"[All Fields] OR \"perforates\"[All Fields] OR \"perforating\"[All Fields] OR \"perforation\"[All Fields] OR \"perforations\"[All Fields] OR \"perforative\"[All Fields] OR \"perforator\"[All Fields] OR \"perforator s\"[All Fields] OR \"perforators\"[All Fields]) OR (\"toxic\"[All Fields] OR \"toxical\"[All Fields] OR \"toxically\"[All Fields] OR \"toxicant\"[All Fields] OR \"toxicant s\"[All Fields] OR \"toxicants\"[All Fields] OR \"toxicated\"[All Fields] OR \"toxication\"[All Fields] OR \"toxicities\"[All Fields] OR \"toxicity\"[MeSH Subheading] OR \"toxicity\"[All Fields] OR \"toxicity s\"[All Fields] OR \"toxics\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 2, "ids": [ "42808289", "42765455" ], "http": 200 }, { "topic": "cochrane-young-onset", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (\"early-onset\" OR \"young-onset\" OR epidemiology OR incidence) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"early-onset\"[All Fields] OR \"young-onset\"[All Fields] OR (\"epidemiologies\"[All Fields] OR \"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"epidemiology\"[MeSH Terms] OR \"epidemiology s\"[All Fields]) OR (\"epidemiology\"[MeSH Subheading] OR \"epidemiology\"[All Fields] OR \"incidence\"[All Fields] OR \"incidence\"[MeSH Terms] OR \"incidences\"[All Fields] OR \"incident\"[All Fields] OR \"incidents\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 21, "ids": [ "42867023", "42861686", "42861682", "42861678", "42841340", "42788405", "42781846", "42775611", "42770376", "42770372", "42765454", "42754260", "42742033", "42741999", "42713886", "42713852", "42695385", "42695349", "42689503", "42680183", "42677895" ], "http": 200 }, { "topic": "cochrane-guidelines", "cochrane": true, "query": "\"Cochrane Database Syst Rev\"[jour] AND (guideline OR consensus) AND (\"2026/08/28\"[Date - Publication] : \"3000\"[Date - Publication])", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"guideline\"[Publication Type] OR \"guidelines as topic\"[MeSH Terms] OR \"guideline\"[All Fields] OR (\"consensual\"[All Fields] OR \"consensually\"[All Fields] OR \"consensus\"[MeSH Terms] OR \"consensus\"[All Fields])) AND 2026/08/28:3000/12/31[Date - Publication]", "count": 4, "ids": [ "42770372", "42764179", "42764178", "42677895" ], "http": 200 } ], "europe_pmc": [ { "topic": "cochrane", "query": "(JOURNAL:\"Cochrane Database of Systematic Reviews\" AND (colorectal OR colon OR rectal)) AND FIRST_PDATE:[2026-08-28 TO 2026-10-19]", "hitCount": 0, "http": 200, "n_returned": 0, "n_without_pmid": 0, "sample_without_pmid": [] }, { "topic": "nopmid-preprint", "query": "(TITLE:\"colorectal\" AND (cancer OR adenocarcinoma)) AND (SRC:PPR) AND FIRST_PDATE:[2026-08-28 TO 2026-10-19]", "hitCount": 123, "http": 200, "n_returned": 60, "n_without_pmid": 60, "sample_without_pmid": [ { "id": "PPR1343932", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.15.759489", "title": "Lipid nanoparticle-mediated RNAi targeting of KRAS mutants sensitises colorectal cancer cells to chemotherapy", "authorString": "Wang Y, Su S, Zahra K, Sang R, Molloy MP, Hutvagner G, Deng W.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-16", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1343913", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.09.757976", "title": "Cross-Platform Evaluation of a Tumor-Budding-Associated Gene Signature in Colorectal Cancer.", "authorString": "Sarkar P, Sarkar P.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-16", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1343705", "source": "PPR", "pmid": null, "doi": "10.21203/rs.3.rs-10284804/v1", "title": "A Culturally Tailored Education Session to Improve Colorectal Cancer Screening Knowledge and Willingness Among Afghan Refugees: A Mixed-Methods Study", "authorString": "Vemulakonda P, Eghbali M, Ezhil SR, Khutsishvili L, Deogaonkar A, Borum M.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-16", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1343438", "source": "PPR", "pmid": null, "doi": "10.20944/preprints202610.1527.v1", "title": "The Optimal Biological Therapy for Conversion in Patients with RAS Wild Type Colorectal Cancer and Unresectable Liver Metastases", "authorString": "Džunić M, Petković I, Cvetanović A, Stojanovic M, Nikolić I, Marković M, Conić I, Krtinić D.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-16", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1343268", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.08.757632", "title": "Cellular proximity and conditional coordination in the colorectal and pancreatic tumor microenvironment: a patient-level analysis of multiplexed imaging", "authorString": "Bhadury S, Frankel TL, Rao A.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-15", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1342860", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.09.758060", "title": "Positive selection and structural disruption of KCNA5 by mutation in colorectal cancer", "authorString": "Xu B, Shorthouse D.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-12", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1342513", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.12.756637", "title": "An RFX-driven ciliogenic cell state defines ex vivo FGFR-inhibitor sensitivity in colorectal cancer", "authorString": "Kralickova L, Miglino N, Esposito C, Pfaendler R, Wegmann R, Cuartero PB, Mena J, Panebianco F, Boos LA, Richter U, Rahimzadeh P, Mehra T, Koelzer VH, Piscuoglio S, Wicki A, Snijder B.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-13", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" }, { "id": "PPR1342405", "source": "PPR", "pmid": null, "doi": "10.64898/2026.10.12.758507", "title": "Chromosome 7 gain establishes a just-right WNT signaling state during colorectal tumorigenesis", "authorString": "Zaalberg IC, Cane Gasull P, Vromans M, Brunet Guasch M, Marcekova N, Vinken A, Middelkamp S, Wardenaar R, Koot D, Carvalho B, Snippert H, Nicholson MD, Foijer F, Schubert M, Lens SM.", "journalTitle": null, "pubYear": "2026", "firstPublicationDate": "2026-10-14", "isOpenAccess": "N", "inEPMC": "N", "pubType": "preprint" } ] }, { "topic": "nopmid-other", "query": "(TITLE:\"colorectal cancer\") AND (SRC:CBA OR SRC:AGR OR SRC:HIR) AND FIRST_PDATE:[2026-08-28 TO 2026-10-19]", "hitCount": 0, "http": 200, "n_returned": 0, "n_without_pmid": 0, "sample_without_pmid": [] }, { "topic": "high-signal", "query": "(TITLE:\"colorectal\" OR TITLE:\"rectal cancer\") AND (randomized OR randomised OR guideline OR consensus OR GLOBOCAN OR ctDNA OR \"phase 3\" OR \"phase III\") AND FIRST_PDATE:[2026-08-28 TO 2026-10-19]", "hitCount": 393, "http": 200, "n_returned": 60, "n_without_pmid": 28, "sample_without_pmid": [ { "id": "PMC13666234", "source": "PMC", "pmid": null, "doi": null, "title": "Preoperative Iron Deficiency Anemia and Frailty in Geriatric Colorectal Cancer Surgery: A Prospective Observational Study", "authorString": "Kaya A, Yılmaz R, Arıcan Ş, Karakol A, Günay H, Büyükbezirci G.", "journalTitle": "J Clin Med", "pubYear": "2026", "firstPublicationDate": "2026-10-01", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "research-article; journal article" }, { "id": "PMC13664734", "source": "PMC", "pmid": null, "doi": null, "title": "In Vitro Modulatory Effect of Stimulant Beverages on the Growth Kinetics of Intestinal Bacteria Associated with Colorectal Cancer", "authorString": "Kudera T, Baigts-Allende D, Fiserova B, Kokoska L.", "journalTitle": "Foods", "pubYear": "2026", "firstPublicationDate": "2026-10-01", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "research-article; journal article" }, { "id": "PMC13664531", "source": "PMC", "pmid": null, "doi": null, "title": "A Contemporary Review of Resectability and Treatment Strategies for Colorectal Liver Metastases: Part 1—Diagnosis, Defining Resectability, and Management of Upfront Resectable and Synchronous Disease", "authorString": "Kalil J, Adam R, Meti N, Metrakos P.", "journalTitle": "Cancers (Basel)", "pubYear": "2026", "firstPublicationDate": "2026-10-01", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "review-article; review; journal article" }, { "id": "PMC13665454", "source": "PMC", "pmid": null, "doi": null, "title": "CWH43 Suppresses Ferroptosis-Associated Vulnerability Through Redox Adaptation in Colorectal Cancer", "authorString": "Tsai K, Wei P, Lee C, Batzorig U, Huang C, Chang Y.", "journalTitle": "Int J Mol Sci", "pubYear": "2026", "firstPublicationDate": "2026-10-01", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "research-article; journal article" }, { "id": "PMC13665136", "source": "PMC", "pmid": null, "doi": null, "title": "Beyond Taxonomy: Fungal Nutraceutical Supplementation Modifies the Functional Potential of the Gut Microbiome in Colorectal Cancer", "authorString": "Rodríguez-Costas N, Rodríguez-Blanco A, Expósito C, Cubiella J, Stompel E, Fernández-de-Ana Portela C, Martín A, Taboada-Rodríguez P, Silva B, Fernández M, Zarraquiños S, Remedios D, Gómez C, Lorenzo S, Poceiro R, Parga M, Ramírez V, Pérez-Castro S.", "journalTitle": "Int J Mol Sci", "pubYear": "2026", "firstPublicationDate": "2026-10-01", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "brief-report; brief report" }, { "id": "PMC13665848", "source": "PMC", "pmid": null, "doi": null, "title": "Pre-Resection Endoscopic Features in T1 Colorectal Cancer Selected for Salvage Surgery After ESD/EID: An Exploratory Comparison of SM1 and SM2–3 Invasion", "authorString": "Maryńczak K, Adamkiewicz J, Kabziński J, Osielczak A, Kasprzyk P, Dziki A, Spychalski M, Majsterek I, Dziki Ł.", "journalTitle": "J Clin Med", "pubYear": "2026", "firstPublicationDate": "2026-10-01", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "research-article; journal article" }, { "id": "PMC13668012", "source": "PMC", "pmid": null, "doi": null, "title": "DeepLNM: A Multimodal Model for Predicting Lymph Node Metastasis in Colorectal Cancer", "authorString": "Zhang Z, Lu C, Wang Z, Cen Z, Zhou Y, Li D, Xie Q, Li B, Guo S, Gan Z, Zhu E, Li J, Aimaier A, Mao R, Qiu W, Zhao C, Tan Y, Liu X, Ma H, Geng T, Wu P, Du H, Wang Y, Liu Y, Liang L.", "journalTitle": "Advanced science", "pubYear": "2026", "firstPublicationDate": "2026-10-14", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "research-article; journal article" }, { "id": "PMC13664725", "source": "PMC", "pmid": null, "doi": null, "title": "Short‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Multicenter Propensity Score‐Matched Analysis Comparing Patients With and Without Preoperative Neoadjuvant Therapy", "authorString": "Shima T, Hamamoto H, Matsuda T, Takemasa I, Tanaka K, Mukai T, Watanabe J, Lee S, Yamamoto S, Naitoh T.", "journalTitle": "Ann Gastroenterol Surg", "pubYear": "2026", "firstPublicationDate": "2026-10-14", "isOpenAccess": "Y", "inEPMC": "Y", "pubType": "research-article; journal article" } ] } ], "ctgov_tracked": [ { "nct": "NCT02008656", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2026-08-24", "results_first_post": null }, { "nct": "NCT02864485", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2026-10-02", "results_first_post": null }, { "nct": "NCT03043313", "overall_status": "COMPLETED", "has_results": true, "last_update_post": "2024-11-26", "results_first_post": "2023-04-18" }, { "nct": "NCT03494946", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2024-02-06", "results_first_post": null }, { "nct": "NCT03803436", "overall_status": "UNKNOWN", "has_results": false, "last_update_post": "2023-03-16", "results_first_post": null }, { "nct": "NCT04008030", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": true, "last_update_post": "2026-08-20", "results_first_post": "2025-09-22" }, { "nct": "NCT04089631", "overall_status": "UNKNOWN", "has_results": false, "last_update_post": "2020-08-06", "results_first_post": null }, { "nct": "NCT04161092", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2024-10-28", "results_first_post": null }, { "nct": "NCT04246684", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2026-08-17", "results_first_post": null }, { "nct": "NCT04607421", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": true, "last_update_post": "2026-06-11", "results_first_post": "2026-06-11" }, { "nct": "NCT04715074", "overall_status": "COMPLETED", "has_results": false, "last_update_post": "2024-03-22", "results_first_post": null }, { "nct": "NCT04812912", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-04-07", "results_first_post": null }, { "nct": "NCT05129787", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2026-02-12", "results_first_post": null }, { "nct": "NCT05198934", "overall_status": "COMPLETED", "has_results": true, "last_update_post": "2026-07-22", "results_first_post": "2026-07-22" }, { "nct": "NCT05723562", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2026-05-26", "results_first_post": null }, { "nct": "NCT05863195", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-09-24", "results_first_post": null }, { "nct": "NCT06185556", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2024-08-23", "results_first_post": null }, { "nct": "NCT06197425", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-05-22", "results_first_post": null }, { "nct": "NCT06202183", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-09-11", "results_first_post": null }, { "nct": "NCT06252649", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-09-03", "results_first_post": null }, { "nct": "NCT06342401", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-07-07", "results_first_post": null }, { "nct": "NCT06558773", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-02-11", "results_first_post": null }, { "nct": "NCT06640049", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2025-11-17", "results_first_post": null }, { "nct": "NCT06733038", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2025-12-08", "results_first_post": null }, { "nct": "NCT06991465", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2025-05-28", "results_first_post": null }, { "nct": "NCT07018869", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-03-31", "results_first_post": null }, { "nct": "NCT07188025", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-10-02", "results_first_post": null }, { "nct": "NCT07227636", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-09-22", "results_first_post": null }, { "nct": "NCT07340567", "overall_status": "ACTIVE_NOT_RECRUITING", "has_results": false, "last_update_post": "2026-07-22", "results_first_post": null }, { "nct": "NCT07562659", "overall_status": "RECRUITING", "has_results": false, "last_update_post": "2026-05-01", "results_first_post": null }, { "nct": "NCT07740720", "overall_status": "NOT_YET_RECRUITING", "has_results": false, "last_update_post": "2026-08-03", "results_first_post": null } ], "ctgov_new": [ { "label": "updated-since-2026-10-12", "http": 200, "n_returned": 30, "query": { "query.term": "AREA[ConditionSearch]\"colorectal cancer\" AND AREA[LastUpdatePostDate]RANGE[2026-10-12,MAX]", "pageSize": "30", "sort": "LastUpdatePostDate" }, "studies": [ { "nct": "NCT04847063", "title": "Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT02484404", "title": "Phase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can...", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT06973564", "title": "JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT07436637", "title": "Guardant Shield Colorectal Cancer Screening", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT06542835", "title": "Community Partnership for Telehealth Solutions to Convey Information and Enhance Care", "status": "COMPLETED", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07621497", "title": "FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable Metastatic Colorectal Cancer (Phase II)", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE2" ] }, { "nct": "NCT07525206", "title": "A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE3" ] }, { "nct": "NCT07878988", "title": "This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT06934538", "title": "First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT05286814", "title": "PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE2" ] }, { "nct": "NCT06253520", "title": "Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT03326791", "title": "Aspirin in Colorectal Cancer Liver Metastases", "status": "COMPLETED", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE2", "PHASE3" ] }, { "nct": "NCT06149481", "title": "Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT07220018", "title": "Colorectal Cancer Screening in the Homeless", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07649655", "title": "EMB-01 in Combination With Chemotherapy for Unresectable or Metastatic Colorectal Cancer", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT07807956", "title": "A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT07328516", "title": "Natural History Study of Early Life Exposures in Agriculture (ELEA)", "status": "ENROLLING_BY_INVITATION", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": null }, { "nct": "NCT01205022", "title": "Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer", "status": "COMPLETED", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT07873450", "title": "SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT07184047", "title": "Longitudinal Geriatric Vulnerability, Chemotherapy Toxicity, and Functional Outcomes in Older Adults With Gastrointestinal Cancer", "status": "COMPLETED", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": null }, { "nct": "NCT07715903", "title": "Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT06200831", "title": "Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07791758", "title": "A Clinical Trial of LBL-024 Combination Drug in Patients With Metastatic Colorectal Carcinoma", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT01174121", "title": "Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE2" ] }, { "nct": "NCT07020221", "title": "A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors", "status": "RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT07541105", "title": "Cancer Awareness Among Syrian Migrants", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07805369", "title": "A Phase 1 Study of DEM301 in Participants With Metastatic Colorectal Cancer", "status": "RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT05292859", "title": "Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs", "status": "COMPLETED", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": null }, { "nct": "NCT07468071", "title": "Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments", "status": "ACTIVE_NOT_RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT07876388", "title": "Compassion-Based Rehabilitation Needs Assessment Following Colorectal Cancer Surgery", "status": "COMPLETED", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "NA" ] } ] }, { "label": "results-first-since-2026-08-28", "http": 200, "n_returned": 9, "query": { "query.term": "AREA[ConditionSearch]\"colorectal cancer\" AND AREA[ResultsFirstPostDate]RANGE[2026-08-28,MAX]", "pageSize": "20" }, "studies": [ { "nct": "NCT04973007", "title": "Comparison of Contrast Agents in Liver Magnetic Resonance (MR) for the Detection of Hepatic Metastases", "status": "TERMINATED", "last_update": "2026-09-25", "has_results": true, "results_first": "2026-09-25", "phases": [ "PHASE4" ] }, { "nct": "NCT06994832", "title": "Using Visual Arrays to Support Understanding of Genetic Risk", "status": "COMPLETED", "last_update": "2026-09-24", "has_results": true, "results_first": "2026-09-24", "phases": [ "NA" ] }, { "nct": "NCT04256707", "title": "Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, Tolerability and Antitumor Activity of Selinexor Combination Treatment", "status": "COMPLETED", "last_update": "2026-10-09", "has_results": true, "results_first": "2026-10-09", "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT06039384", "title": "A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation", "status": "TERMINATED", "last_update": "2026-09-08", "has_results": true, "results_first": "2026-09-08", "phases": [ "PHASE1" ] }, { "nct": "NCT01329809", "title": "Neoadjuvant Recombinant Vaccinia Virus for Metastatic Colorectal Cancer With Liver Resection", "status": "TERMINATED", "last_update": "2026-10-02", "has_results": true, "results_first": "2026-10-02", "phases": [ "PHASE2" ] }, { "nct": "NCT04844073", "title": "A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer", "status": "TERMINATED", "last_update": "2026-09-24", "has_results": true, "results_first": "2026-09-24", "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT05641896", "title": "Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers", "status": "COMPLETED", "last_update": "2026-10-01", "has_results": true, "results_first": "2026-10-01", "phases": [ "PHASE2" ] }, { "nct": "NCT03366155", "title": "Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver", "status": "COMPLETED", "last_update": "2026-08-28", "has_results": true, "results_first": "2026-08-28", "phases": [ "PHASE2" ] }, { "nct": "NCT04427527", "title": "Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia", "status": "COMPLETED", "last_update": "2026-09-04", "has_results": true, "results_first": "2026-09-04", "phases": [ "NA" ] } ] }, { "label": "first-posted-since-2026-10-12", "http": 200, "n_returned": 11, "query": { "query.term": "AREA[ConditionSearch]\"colorectal cancer\" AND AREA[StudyFirstPostDate]RANGE[2026-10-12,MAX]", "pageSize": "20" }, "studies": [ { "nct": "NCT07874035", "title": "Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia", "status": "RECRUITING", "last_update": "2026-10-14", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07872787", "title": "NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-14", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07878988", "title": "This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT07876388", "title": "Compassion-Based Rehabilitation Needs Assessment Following Colorectal Cancer Surgery", "status": "COMPLETED", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07875465", "title": "Intestinal Low-Dose Radiotherapy Combined With Immune Checkpoint Inhibitors in Solid Tumors With Liver Metastases", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "PHASE2" ] }, { "nct": "NCT07874880", "title": "MTX-531-001 Phase 1 Study in Advanced Solid Tumors", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT07873450", "title": "SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET", "status": "RECRUITING", "last_update": "2026-10-16", "has_results": false, "results_first": null, "phases": [ "PHASE1", "PHASE2" ] }, { "nct": "NCT07871253", "title": "Therapeutic Efficacy and Safety of Ultrasound-Guided Microwave Ablation for Hepatic Metastatic Nodules", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-13", "has_results": false, "results_first": null, "phases": [ "NA" ] }, { "nct": "NCT07873580", "title": "European Implementation Study on Simultaneous Screening for Gastric and Colorectal Cancers", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-14", "has_results": false, "results_first": null, "phases": null }, { "nct": "NCT07875920", "title": "Phase 1 Study of NW-301V TCR-T Cells in Advanced Solid Tumors With KRAS G12V Mutation", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-15", "has_results": false, "results_first": null, "phases": [ "PHASE1" ] }, { "nct": "NCT07874438", "title": "A Prospective, Single-Arm, Multicenter, Phase II Clinical Study of Iparomlimab and Tuvonralimab (QL1706) Combined With Cetuximab and mFOLFIRI Regimen as First-Line Treatment for Recurrent or Metastatic Colorectal Cancer", "status": "NOT_YET_RECRUITING", "last_update": "2026-10-14", "has_results": false, "results_first": null, "phases": [ "NA" ] } ] } ], "retraction_window": [ { "pmid": "42825377", "title": "[Expression of Concern] ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer.", "pubtypes": [ "Journal Article", "Expression of Concern" ], "in_bibliography": false }, { "pmid": "42844080", "title": "Expression of Concern: Fini L, Selgrad M, Fogliano V, Graziani G, Romano M, Hotchkiss E, Daoud YA, De Vol EB, Boland CR, Ricciardiello L. Annurca Apple Polyphenols Have Potent Demethylating Activity and Can Reactivate Silenced Tumor Suppressor Genes in Colorectal Cancer Cells. J Nutr. 2007;137:2622-2628.", "pubtypes": [ "Journal Article", "Expression of Concern" ], "in_bibliography": false }, { "pmid": "42865666", "title": "Expression of Concern: Butyrate suppresses glucose metabolism of colorectal cancer cells via GPR109a-AKT signaling pathway and enhances chemotherapy.", "pubtypes": [ "Expression of Concern" ], "in_bibliography": false } ], "added_records": [ { "pmid": "41932450", "title": "Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.", "source": "Gastroenterology", "pubdate": "2026 Sep", "doi": "10.1053/j.gastro.2026.02.047", "pubtypes": [ "Systematic Review", "Journal Article", "Network Meta-Analysis" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42575119", "title": "A blood-based test for detection of advanced adenomas and colorectal cancer (DENEB): a multicentre diagnostic accuracy study.", "source": "Lancet Gastroenterol Hepatol", "pubdate": "2026 Oct", "doi": "10.1016/S2468-1253(26)00180-9", "pubtypes": [ "Journal Article", "Multicenter Study", "Research Support, N.I.H., Extramural" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42142544", "title": "Nonadvanced Adenoma Number and Size as Predictors of Metachronous Advanced Colorectal Neoplasm: Implications for Surveillance Guidelines.", "source": "Gastroenterology", "pubdate": "2026 Oct", "doi": "10.1053/j.gastro.2026.04.037", "pubtypes": [ "Journal Article" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42492015", "title": "Total Neoadjuvant Therapy With Long-Course Radiotherapy Versus Chemoradiotherapy in High-Risk Locally Advanced Rectal Cancer (TNTCRT): A Multicenter, Randomized, Phase III Trial.", "source": "J Clin Oncol", "pubdate": "2026 Sep", "doi": "10.1200/JCO-25-03110", "pubtypes": [ "Journal Article", "Clinical Trial, Phase III", "Multicenter Study", "Randomized Controlled Trial", "Comparative Study", "Research Support, Non-U.S. Gov't" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42633754", "title": "Chemoradiotherapy versus short-course radiotherapy for response-adapted organ preservation in early-stage and intermediate-stage rectal cancer (STAR-TREC): 12-month results of an international, multicentre, open-label, parallel-group, randomised, phase 2/3 trial.", "source": "Lancet Oncol", "pubdate": "2026 Sep", "doi": "10.1016/S1470-2045(26)00228-7", "pubtypes": [ "Journal Article", "Multicenter Study", "Randomized Controlled Trial", "Clinical Trial, Phase II", "Clinical Trial, Phase III", "Comparative Study" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42507974", "title": "Five-Year Outcomes of Short-Term Radiotherapy Plus Chemotherapy Versus Long-Term Chemoradiotherapy for Locally Advanced Rectal Cancer: Updated Results of the STELLAR Trial.", "source": "J Clin Oncol", "pubdate": "2026 Sep", "doi": "10.1200/JCO-25-02387", "pubtypes": [ "Journal Article", "Randomized Controlled Trial", "Comparative Study" ], "retraction_flag_pubmed": false, "crossref_updated_by": [ "correction" ] }, { "pmid": "42545685", "title": "Addition of High-Dose Vitamin D3 to Standard Treatment in Patients With Metastatic Colorectal Cancer: The SOLARIS Randomized Clinical Trial (Alliance A021703).", "source": "JAMA", "pubdate": "2026 Sep 1", "doi": "10.1001/jama.2026.9350", "pubtypes": [ "Clinical Trial, Phase III", "Comparative Study", "Journal Article", "Multicenter Study", "Randomized Controlled Trial" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42525921", "title": "COMMIT: A Randomized Study of mFOLFOX6/Bevacizumab/Atezolizumab or Atezolizumab Alone as First-Line Treatment of Deficient DNA Mismatch Repair Metastatic Colorectal Cancer.", "source": "J Clin Oncol", "pubdate": "2026 Oct 10", "doi": "10.1200/JCO-25-03052", "pubtypes": [ "Journal Article", "Randomized Controlled Trial", "Clinical Trial, Phase III", "Multicenter Study" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42389808", "title": "UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx).", "source": "Br J Clin Pharmacol", "pubdate": "2026 Sep", "doi": "10.1002/bcp.70659", "pubtypes": [ "Journal Article", "Practice Guideline" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42397676", "title": "Circulating Tumor DNA Status and Adjuvant Chemotherapy in Resected Colorectal Liver Metastases.", "source": "JAMA Oncol", "pubdate": "2026 Sep 1", "doi": "10.1001/jamaoncol.2026.2191", "pubtypes": [ "Journal Article" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42425127", "title": "Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial.", "source": "Lancet Gastroenterol Hepatol", "pubdate": "2026 Sep", "doi": "10.1016/S2468-1253(26)00114-7", "pubtypes": [ "Journal Article", "Multicenter Study", "Randomized Controlled Trial", "Equivalence Trial", "Research Support, Non-U.S. Gov't" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42692037", "title": "Germline multigene panel testing for colorectal cancer: a systematic review and meta-analysis.", "source": "Lancet Gastroenterol Hepatol", "pubdate": "2026 Nov", "doi": "10.1016/S2468-1253(26)00187-1", "pubtypes": [ "Journal Article", "Systematic Review", "Meta-Analysis" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42728028", "title": "Heterozygous germline mutations in MSH3, and probably MLH3, act as classical tumour suppressors, leading to excess somatic deletion mutations, signature ID4 and increased colorectal cancer risk.", "source": "Gut", "pubdate": "2026 Sep 11", "doi": "10.1136/gutjnl-2026-338390", "pubtypes": [ "Journal Article" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "41770836", "title": "Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement.", "source": "Gut", "pubdate": "2026 Sep 7", "doi": "10.1136/gutjnl-2025-337374", "pubtypes": [ "Journal Article", "Consensus Statement" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "41748160", "title": "Consensus guidance of immune checkpoint inhibitors in locally advanced rectal cancer.", "source": "Gut", "pubdate": "2026 Oct 7", "doi": "10.1136/gutjnl-2025-336979", "pubtypes": [ "Consensus Statement", "Journal Article" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] }, { "pmid": "42789827", "title": "Erratum: Five-Year Outcomes of Short-Term Radiotherapy Plus Chemotherapy Versus Long-Term Chemoradiotherapy for Locally Advanced Rectal Cancer: Updated Results of the STELLAR Trial.", "source": "J Clin Oncol", "pubdate": "2026 Sep 25", "doi": "10.1200/JCO-26-02343", "pubtypes": [ "Journal Article", "Published Erratum" ], "retraction_flag_pubmed": false, "crossref_updated_by": [] } ], "notes": { "cochrane_crc_relevant": [ "42770376" ], "stellar_correction": "PMID 42507974 Crossref updated-by correction DOI 10.1200/jco-26-02343 (PMID 42789827); 5-year OS numbers not restated in wiki", "cadly2_erratum": "PMID 42462747 Crossref erratum; not added to wiki", "nccn_living": "Colon and Rectal Version 2.2026 on public NCCN pages 2026-10-19", "tracked_nct_status_changes_since_2026-10-12": [] } }