{ "condition": "bipolar-disorder", "sweep_date": "2026-10-23", "engine": "Grok", "window": { "date_from": "2026-08-28", "date_to": "2026-10-23", "pubmed_primary": "pdat", "supplement": "edat catch-all and incremental edat since 2026-10-17", "note": "2026-08-28 through 2026-10-16 was searched on 2026-10-16. This sweep repeats that query set with maxdate 2026-10-23 and triages PMIDs absent from the prior returned sets and the bibliography." }, "contact_email_used": false, "unpaywall": "skipped; LIFEBANK_CONTACT_EMAIL unset", "not_searched": [ "CENTRAL (cochranelibrary.com HTTP 403 this session)", "SciELO HTTP 403 this session", "LILACS timed out this session", "WHO ICTRP HTTP 502 this session", "ChiCTR homepage fetched; no date-filtered search completed", "EU CTR search page HTTP 200; results not parsed, so not claimed as searched", "OpenAlex and DOAJ not queried", "Embase, Scopus, Web of Science unavailable", "Unpaywall skipped" ], "mortality_retry": { "count": "103", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"suicid*\"[Title/Abstract] OR \"mortality\"[Title/Abstract] OR \"cardiovascular\"[Title/Abstract] OR \"metabolic\"[Title/Abstract] OR \"obesity\"[Title/Abstract] OR \"diabetes\"[Title/Abstract] OR \"life expectancy\"[Title/Abstract] OR \"dementia\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "new": [ "42902526", "42901238", "42898785", "42897416", "42892769", "42887787", "42083011" ], "error": null, "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28suicid%2A%5Btiab%5D+OR+mortality%5Btiab%5D+OR+cardiovascular%5Btiab%5D+OR+metabolic%5Btiab%5D+OR+obesity%5Btiab%5D+OR+diabetes%5Btiab%5D+OR+%22life+expectancy%22%5Btiab%5D+OR+dementia%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "note_mortality_first_attempt": "The first mortality esearch in pubmed_esearch returned HTTP 429 and is preserved with count null. The retry in mortality_retry succeeded (count 103).", "pubmed_esearch": { "diagnosis": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (diagnos*[ti] OR misdiagnos*[tiab] OR screening[ti] OR spectrum[ti] OR \"mixed features\"[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28diagnos%2A%5Bti%5D+OR+misdiagnos%2A%5Btiab%5D+OR+screening%5Bti%5D+OR+spectrum%5Bti%5D+OR+%22mixed+features%22%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "45", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"diagnos*\"[Title] OR \"misdiagnos*\"[Title/Abstract] OR \"screening\"[Title] OR \"spectrum\"[Title] OR \"mixed features\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "43", "new_vs_prior_sweep": [ "42901238", "42894408" ], "pmids": [ "42901238", "42894408", "42881021", "42878529", "42877807", "42869174", "42847037", "42838229", "42833865", "42829941", "42815730", "42807653", "42806848", "42786613", "42779463", "42775184", "42753132", "42716347", "42716345", "42716056", "42709031", "42702788", "42700777", "42686073", "42684694", "42675803", "42670435", "42669383", "42586082", "42576393", "42483161", "42442754", "42385293", "42315454", "42167699", "42142757", "42112712", "42106928", "42096890", "42092401", "42070700", "42014469", "41396193", "41352431", "39786681" ] }, "epidemiology": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (prevalence[tiab] OR incidence[tiab] OR cohort[ti] OR registry[tiab] OR \"global burden\"[tiab] OR course[ti])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28prevalence%5Btiab%5D+OR+incidence%5Btiab%5D+OR+cohort%5Bti%5D+OR+registry%5Btiab%5D+OR+%22global+burden%22%5Btiab%5D+OR+course%5Bti%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "66", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"prevalence\"[Title/Abstract] OR \"incidence\"[Title/Abstract] OR \"cohort\"[Title] OR \"registry\"[Title/Abstract] OR \"global burden\"[Title/Abstract] OR \"course\"[Title]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "62", "new_vs_prior_sweep": [ "42902526", "42894408", "42890433", "42887786" ], "pmids": [ "42902526", "42894408", "42890433", "42887786", "42880607", "42878529", "42878230", "42877241", "42859432", "42858466", "42850618", "42840883", "42839929", "42838826", "42838229", "42836891", "42830172", "42815348", "42815091", "42810282", "42789592", "42783804", "42770535", "42765379", "42758600", "42757275", "42754622", "42727204", "42723029", "42713675", "42711749", "32644424", "42711066", "42708514", "42700777", "42697570", "42688558", "42688390", "42678618", "42674302", "42670435", "42642929", "42600836", "42586082", "42578538", "42492718", "42377482", "42349060", "42337416", "42335719", "42330862", "42324672", "42296714", "42242171", "42215638", "42189148", "42125886", "42106928", "42050794", "41935922", "41924987", "41820247", "41790247", "41351381", "41109839", "40364549" ] }, "genetics": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (genetic*[ti] OR GWAS[tiab] OR genome-wide[tiab] OR polygenic[tiab] OR \"copy number\"[tiab] OR heritab*[tiab] OR Mendelian[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28genetic%2A%5Bti%5D+OR+GWAS%5Btiab%5D+OR+genome-wide%5Btiab%5D+OR+polygenic%5Btiab%5D+OR+%22copy+number%22%5Btiab%5D+OR+heritab%2A%5Btiab%5D+OR+Mendelian%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "27", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"genetic*\"[Title] OR \"GWAS\"[Title/Abstract] OR \"genome-wide\"[Title/Abstract] OR \"polygenic\"[Title/Abstract] OR \"copy number\"[Title/Abstract] OR \"heritab*\"[Title/Abstract] OR \"Mendelian\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "26", "new_vs_prior_sweep": [ "42892769" ], "pmids": [ "42892769", "42880378", "42876217", "42858466", "42844253", "42841250", "42825385", "42813637", "42743600", "42642929", "42625058", "42608581", "42569312", "42542118", "42526346", "42465921", "42320287", "42320286", "42308110", "42267832", "42203964", "42168580", "42162625", "42135523", "42107657", "42020718", "41755539" ] }, "neurobiology": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (MRI[tiab] OR neuroimaging[tiab] OR circadian[tiab] OR mitochondri*[tiab] OR inflammat*[ti])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28MRI%5Btiab%5D+OR+neuroimaging%5Btiab%5D+OR+circadian%5Btiab%5D+OR+mitochondri%2A%5Btiab%5D+OR+inflammat%2A%5Bti%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "69", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"MRI\"[Title/Abstract] OR \"neuroimaging\"[Title/Abstract] OR \"circadian\"[Title/Abstract] OR \"mitochondri*\"[Title/Abstract] OR \"inflammat*\"[Title]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "65", "new_vs_prior_sweep": [ "42901238", "42892769", "42887787", "42617977" ], "pmids": [ "42901238", "42892769", "42887787", "42880378", "42868737", "42863801", "42851418", "42847037", "42840883", "42839301", "42836332", "42826877", "42825385", "42823992", "42812653", "42803524", "42797527", "42797424", "42796993", "42794424", "42793041", "42790157", "42786849", "42786613", "42773517", "42757275", "42751051", "42743600", "42700777", "42700485", "42693835", "42687371", "42659872", "42657624", "42617977", "42581396", "42570035", "42569312", "42568249", "42542118", "42541933", "42508239", "42503444", "42502622", "42465921", "42434329", "42418870", "42399489", "42398295", "42350629", "42337416", "42319208", "42315454", "42263791", "42190847", "42184576", "42167699", "42162625", "42103244", "42103240", "42092401", "42070700", "41903946", "41854950", "41755539", "41690355", "41621866", "41621592", "41351381" ] }, "mania": { "query": "(mania[tiab] OR manic[tiab] OR \"mixed episode\"[tiab] OR \"mixed features\"[tiab]) AND (\"bipolar disorder\"[mh] OR bipolar[tiab]) AND (treatment[tiab] OR trial[tiab] OR antipsychotic*[tiab] OR agitation[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28mania%5Btiab%5D+OR+manic%5Btiab%5D+OR+%22mixed+episode%22%5Btiab%5D+OR+%22mixed+features%22%5Btiab%5D%29+AND+%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Btiab%5D%29+AND+%28treatment%5Btiab%5D+OR+trial%5Btiab%5D+OR+antipsychotic%2A%5Btiab%5D+OR+agitation%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "57", "translation": "(\"mania\"[Title/Abstract] OR \"manic\"[Title/Abstract] OR \"mixed episode\"[Title/Abstract] OR \"mixed features\"[Title/Abstract]) AND (\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title/Abstract]) AND (\"treatment\"[Title/Abstract] OR \"trial\"[Title/Abstract] OR \"antipsychotic*\"[Title/Abstract] OR \"agitation\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "50", "new_vs_prior_sweep": [ "42905247", "42904336", "42901238", "42901213", "42898785", "42887787", "42083011" ], "pmids": [ "42905247", "42904336", "42901238", "42901213", "42898785", "42887787", "42850786", "42850618", "42836332", "42836128", "42833410", "42832826", "42830594", "42823992", "42815732", "42807653", "42803750", "42786849", "42765891", "42762875", "42737920", "30855854", "42729250", "42725756", "42719610", "42716056", "42711749", "32644424", "42709031", "42708514", "42698177", "42694657", "42684694", "42684674", "42675803", "42670435", "42600836", "42581396", "42568896", "42542118", "42528360", "42502622", "42296714", "42263791", "42215638", "42214296", "42112712", "42103240", "42096890", "42085651", "42083011", "42047475", "42035800", "41964330", "41558805", "41396193", "41109839" ] }, "depression": { "query": "\"bipolar depression\"[tiab] OR (\"bipolar disorder\"[mh] AND depress*[ti] AND (treatment OR trial OR efficacy))", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22bipolar+depression%22%5Btiab%5D+OR+%28%22bipolar+disorder%22%5Bmh%5D+AND+depress%2A%5Bti%5D+AND+%28treatment+OR+trial+OR+efficacy%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "48", "translation": "(\"bipolar depression\"[Title/Abstract] OR (\"bipolar disorder\"[MeSH Terms] AND \"depress*\"[Title] AND (\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"treatments\"[All Fields] OR \"therapy\"[MeSH Subheading] OR \"therapy\"[All Fields] OR \"treatment\"[All Fields] OR \"treatment s\"[All Fields] OR (\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]) OR (\"efficacies\"[All Fields] OR \"efficacious\"[All Fields] OR \"efficaciously\"[All Fields] OR \"efficaciousness\"[All Fields] OR \"efficacy\"[All Fields])))) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "47", "new_vs_prior_sweep": [ "42906286" ], "pmids": [ "42906286", "42878230", "42863801", "42859565", "42842759", "42836128", "42832826", "42815730", "42815432", "42812927", "42806848", "42803524", "42799904", "42783804", "42773517", "42767564", "42765891", "42762641", "42751051", "42748866", "42737920", "42729250", "42725756", "42721112", "42716345", "42684694", "42676118", "42675468", "42670435", "42670081", "42669383", "42649425", "42581396", "42542118", "42528360", "42502622", "42203049", "42184576", "42173043", "42106928", "42105579", "42103244", "42087328", "41947665", "41785480", "41785475", "41558805", "39564233" ] }, "maintenance": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (maintenance[tiab] OR relapse[tiab] OR recurrence[tiab] OR \"long-acting injectable\"[tiab] OR lamotrigine[tiab] OR valproate[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28maintenance%5Btiab%5D+OR+relapse%5Btiab%5D+OR+recurrence%5Btiab%5D+OR+%22long-acting+injectable%22%5Btiab%5D+OR+lamotrigine%5Btiab%5D+OR+valproate%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "50", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"maintenance\"[Title/Abstract] OR \"relapse\"[Title/Abstract] OR \"recurrence\"[Title/Abstract] OR \"long-acting injectable\"[Title/Abstract] OR \"lamotrigine\"[Title/Abstract] OR \"valproate\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "46", "new_vs_prior_sweep": [ "42898785", "42894408", "42890433", "40913696" ], "pmids": [ "42898785", "42894408", "42890433", "42859565", "42851418", "42850618", "42849015", "42839929", "42836128", "42825604", "42819869", "42815732", "42807653", "42797424", "42796993", "42775184", "42772525", "42765379", "42762641", "42758600", "42756307", "42736512", "42716056", "42711749", "32644424", "42711066", "42700485", "42693835", "42689941", "42687371", "42670081", "42600836", "42569600", "42489486", "42349060", "42337416", "42324672", "42307011", "42242171", "42216627", "42142757", "42134743", "42130270", "42095358", "42069105", "42035591", "41972283", "41924987", "41848268", "40913696" ] }, "lithium": { "query": "lithium[ti] AND (bipolar[tiab] OR mood[tiab] OR kidney[tiab] OR renal[tiab] OR thyroid[tiab] OR suicide[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=lithium%5Bti%5D+AND+%28bipolar%5Btiab%5D+OR+mood%5Btiab%5D+OR+kidney%5Btiab%5D+OR+renal%5Btiab%5D+OR+thyroid%5Btiab%5D+OR+suicide%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "44", "translation": "\"lithium\"[Title] AND (\"bipolar\"[Title/Abstract] OR \"mood\"[Title/Abstract] OR \"kidney\"[Title/Abstract] OR \"renal\"[Title/Abstract] OR \"thyroid\"[Title/Abstract] OR \"suicide\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "42", "new_vs_prior_sweep": [ "42889102", "42083011" ], "pmids": [ "42889102", "42871752", "42865315", "42850782", "42847926", "42847418", "42841250", "42839929", "42830608", "42830172", "42825604", "42810282", "42801475", "42800178", "42797424", "42790389", "42786849", "42775117", "42770460", "42765379", "42750579", "42750371", "42747205", "42742966", "42721208", "42708944", "42708514", "42683441", "42676950", "42674302", "42640790", "42489486", "42372694", "42349821", "42349060", "42268602", "42263791", "42216627", "42184576", "42130270", "42095851", "42083011", "42035591", "41621866" ] }, "antidepressant": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (antidepressant*[tiab] OR \"treatment-emergent\"[tiab] OR switch[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28antidepressant%2A%5Btiab%5D+OR+%22treatment-emergent%22%5Btiab%5D+OR+switch%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "34", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"antidepressant*\"[Title/Abstract] OR \"treatment-emergent\"[Title/Abstract] OR \"switch\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "30", "new_vs_prior_sweep": [ "42906709", "42906286", "42904336", "42887787" ], "pmids": [ "42906709", "42906286", "42904336", "42887787", "42846741", "42842759", "42819869", "42793368", "42762641", "42752982", "42716345", "42693835", "42688594", "42687371", "42684694", "42647834", "42600836", "42581396", "42578538", "42569600", "42542118", "42528360", "42521114", "42503444", "42492718", "42330862", "42216627", "42203049", "42142757", "42130202", "42105579", "42103244", "42035800", "41903946" ] }, "psychotherapy": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (psychotherap*[tiab] OR psychoeducation[tiab] OR cognitive[ti] OR \"family-focused\"[tiab] OR \"self-management\"[tiab] OR digital[tiab] OR smartphone[tiab] OR app[tiab] OR lifestyle[tiab] OR exercise[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28psychotherap%2A%5Btiab%5D+OR+psychoeducation%5Btiab%5D+OR+cognitive%5Bti%5D+OR+%22family-focused%22%5Btiab%5D+OR+%22self-management%22%5Btiab%5D+OR+digital%5Btiab%5D+OR+smartphone%5Btiab%5D+OR+app%5Btiab%5D+OR+lifestyle%5Btiab%5D+OR+exercise%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "61", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"psychotherap*\"[Title/Abstract] OR \"psychoeducation\"[Title/Abstract] OR \"cognitive\"[Title] OR \"family-focused\"[Title/Abstract] OR \"self-management\"[Title/Abstract] OR \"digital\"[Title/Abstract] OR \"smartphone\"[Title/Abstract] OR \"app\"[Title/Abstract] OR \"lifestyle\"[Title/Abstract] OR \"exercise\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "53", "new_vs_prior_sweep": [ "42906286", "42904336", "42902526", "42902289", "42901238", "42892191", "42887787", "42883387" ], "pmids": [ "42906286", "42904336", "42902526", "42902289", "42901238", "42892191", "42887787", "42883387", "42879783", "42844253", "42838229", "42826877", "42825385", "42799438", "42786204", "42783804", "42770514", "42765891", "42765378", "42762641", "42756115", "42736445", "42735779", "42729350", "42729250", "42727520", "42725756", "42721927", "42713675", "42710717", "42702273", "42700485", "42649425", "42585755", "42569600", "42569312", "42549780", "42542119", "42481733", "42445981", "42418908", "42398295", "42391980", "42385293", "42337416", "42215638", "42190891", "42142751", "42103240", "42095358", "42092401", "42087328", "42059153", "42050794", "41964330", "41848268", "41789712", "41690355", "41621592", "41558805", "41275966" ] }, "comorbidity": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (ADHD[tiab] OR \"substance use\"[tiab] OR alcohol[tiab] OR cannabis[tiab] OR anxiety[ti] OR borderline[tiab] OR comorbid*[tiab] OR \"differential diagnosis\"[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28ADHD%5Btiab%5D+OR+%22substance+use%22%5Btiab%5D+OR+alcohol%5Btiab%5D+OR+cannabis%5Btiab%5D+OR+anxiety%5Bti%5D+OR+borderline%5Btiab%5D+OR+comorbid%2A%5Btiab%5D+OR+%22differential+diagnosis%22%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "85", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"ADHD\"[Title/Abstract] OR \"substance use\"[Title/Abstract] OR \"alcohol\"[Title/Abstract] OR \"cannabis\"[Title/Abstract] OR \"anxiety\"[Title] OR \"borderline\"[Title/Abstract] OR \"comorbid*\"[Title/Abstract] OR \"differential diagnosis\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "80", "new_vs_prior_sweep": [ "42902526", "42901238", "42897416", "42894408", "42892191" ], "pmids": [ "42902526", "42901238", "42897416", "42894408", "42892191", "42880607", "42878529", "42877241", "42876217", "42863796", "42863721", "42862819", "42858455", "42856213", "42851418", "42847037", "42840883", "42839301", "42838231", "42836891", "42823992", "42819869", "42814595", "42814580", "42812653", "42806848", "42803524", "42794424", "42793368", "42789592", "42786849", "42766403", "42758340", "42757275", "42756115", "42752982", "42749683", "42748866", "42735776", "42729350", "42725756", "42721947", "42716347", "42713675", "32644424", "42708514", "42700777", "42686314", "42680113", "42675803", "42675562", "42670435", "42669383", "42647834", "42625058", "42611127", "42586082", "42578538", "42508177", "42481733", "42443536", "42424705", "42399489", "42341384", "42320288", "42314953", "42267832", "42189148", "42173043", "42165752", "42142749", "42106928", "42055136", "42054082", "42047475", "42035800", "42020718", "41820247", "41790247", "41789712", "41755539", "41690355", "41421869", "41351381", "41109839" ] }, "mortality": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (suicid*[tiab] OR mortality[tiab] OR cardiovascular[tiab] OR metabolic[tiab] OR obesity[tiab] OR diabetes[tiab] OR \"life expectancy\"[tiab] OR dementia[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28suicid%2A%5Btiab%5D+OR+mortality%5Btiab%5D+OR+cardiovascular%5Btiab%5D+OR+metabolic%5Btiab%5D+OR+obesity%5Btiab%5D+OR+diabetes%5Btiab%5D+OR+%22life+expectancy%22%5Btiab%5D+OR+dementia%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": null, "translation": null, "error": "HTTP 429: Too Many Requests", "prior_count": "96", "new_vs_prior_sweep": [], "pmids": [] }, "pregnancy": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (pregnan*[tiab] OR postpartum[tiab] OR perinatal[tiab] OR lactation[tiab] OR breastfeeding[tiab] OR teratogen*[tiab] OR menopaus*[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28pregnan%2A%5Btiab%5D+OR+postpartum%5Btiab%5D+OR+perinatal%5Btiab%5D+OR+lactation%5Btiab%5D+OR+breastfeeding%5Btiab%5D+OR+teratogen%2A%5Btiab%5D+OR+menopaus%2A%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "9", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"pregnan*\"[Title/Abstract] OR \"postpartum\"[Title/Abstract] OR \"perinatal\"[Title/Abstract] OR \"lactation\"[Title/Abstract] OR \"breastfeeding\"[Title/Abstract] OR \"teratogen*\"[Title/Abstract] OR \"menopaus*\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "7", "new_vs_prior_sweep": [ "42898785", "42887786" ], "pmids": [ "42898785", "42887786", "42850618", "42825604", "42758600", "42135523", "42103240", "42085651", "41996964" ] }, "guidelines": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (guideline*[ti] OR consensus[ti] OR recommendation*[ti] OR practice guideline[pt])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28guideline%2A%5Bti%5D+OR+consensus%5Bti%5D+OR+recommendation%2A%5Bti%5D+OR+practice+guideline%5Bpt%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "4", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"guideline*\"[Title] OR \"consensus\"[Title] OR \"recommendation*\"[Title] OR \"practice guideline\"[Publication Type]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "4", "new_vs_prior_sweep": [], "pmids": [ "42768410", "42762875", "42489486", "41972283" ] }, "biomarkers": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (biomarker*[tiab] OR actigraph*[tiab] OR \"digital phenotyp*\"[tiab] OR \"machine learning\"[tiab] OR speech[tiab] OR wearable*[tiab] OR \"passive sensing\"[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28biomarker%2A%5Btiab%5D+OR+actigraph%2A%5Btiab%5D+OR+%22digital+phenotyp%2A%22%5Btiab%5D+OR+%22machine+learning%22%5Btiab%5D+OR+speech%5Btiab%5D+OR+wearable%2A%5Btiab%5D+OR+%22passive+sensing%22%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "67", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"biomarker*\"[Title/Abstract] OR \"actigraph*\"[Title/Abstract] OR \"digital phenotyp*\"[Title/Abstract] OR \"machine learning\"[Title/Abstract] OR \"speech\"[Title/Abstract] OR \"wearable*\"[Title/Abstract] OR \"passive sensing\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "64", "new_vs_prior_sweep": [ "42906709", "42898785", "42785390" ], "pmids": [ "42906709", "42898785", "42880378", "42879783", "42877807", "42870751", "42863721", "42849864", "42841250", "42840883", "42839301", "42836128", "42833865", "42830172", "42823992", "42815091", "42807653", "42806848", "42803524", "42797527", "42794424", "42786613", "42785390", "42783804", "42782583", "42779463", "42772525", "42767042", "42765378", "42751051", "42735776", "42729831", "42725756", "42721112", "42716347", "42702788", "42700485", "42691792", "42689941", "42670081", "42669383", "42657624", "42608581", "42542118", "42526346", "42508239", "42503444", "42471042", "42462336", "42430806", "42398295", "42364336", "42341357", "42337416", "42314953", "42217402", "42190891", "42190847", "42184576", "42142752", "42112712", "42096890", "42095358", "42090938", "42014469", "41935922", "41351381" ] }, "trials": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (randomized controlled trial[pt] OR \"randomised\"[ti] OR \"randomized\"[ti] OR \"phase 3\"[tiab] OR \"phase III\"[tiab] OR \"phase 2\"[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28randomized+controlled+trial%5Bpt%5D+OR+%22randomised%22%5Bti%5D+OR+%22randomized%22%5Bti%5D+OR+%22phase+3%22%5Btiab%5D+OR+%22phase+III%22%5Btiab%5D+OR+%22phase+2%22%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "23", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"randomized controlled trial\"[Publication Type] OR \"randomised\"[Title] OR \"randomized\"[Title] OR \"phase 3\"[Title/Abstract] OR \"phase III\"[Title/Abstract] OR \"phase 2\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "23", "new_vs_prior_sweep": [], "pmids": [ "42863911", "42847035", "42845271", "42838229", "42783804", "42736512", "42729250", "42685986", "42684694", "42675468", "42592752", "42581396", "42549780", "42481733", "42337416", "42203049", "42142751", "42087328", "41964330", "41848268", "41785480", "41558805", "41131937" ] }, "neuromod": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (ketamine[tiab] OR esketamine[tiab] OR \"electroconvulsive\"[tiab] OR TMS[tiab] OR \"transcranial\"[tiab] OR psilocybin[tiab] OR ketogenic[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28ketamine%5Btiab%5D+OR+esketamine%5Btiab%5D+OR+%22electroconvulsive%22%5Btiab%5D+OR+TMS%5Btiab%5D+OR+%22transcranial%22%5Btiab%5D+OR+psilocybin%5Btiab%5D+OR+ketogenic%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "24", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"ketamine\"[Title/Abstract] OR \"esketamine\"[Title/Abstract] OR \"electroconvulsive\"[Title/Abstract] OR \"TMS\"[Title/Abstract] OR \"transcranial\"[Title/Abstract] OR \"psilocybin\"[Title/Abstract] OR \"ketogenic\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "22", "new_vs_prior_sweep": [ "42906286", "42898785" ], "pmids": [ "42906286", "42898785", "42878230", "42842759", "42819869", "42814595", "42803524", "42765891", "42762641", "42758023", "42748866", "42721112", "42684694", "42675468", "42670081", "42581396", "42502622", "42228986", "42215638", "42103244", "42090938", "42087328", "41690355", "39961034" ] }, "patient": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (stigma[tiab] OR qualitative[tiab] OR \"lived experience\"[tiab] OR \"patient-reported\"[tiab] OR recovery[ti] OR caregiver*[tiab] OR employment[tiab] OR adherence[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28stigma%5Btiab%5D+OR+qualitative%5Btiab%5D+OR+%22lived+experience%22%5Btiab%5D+OR+%22patient-reported%22%5Btiab%5D+OR+recovery%5Bti%5D+OR+caregiver%2A%5Btiab%5D+OR+employment%5Btiab%5D+OR+adherence%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "47", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"stigma\"[Title/Abstract] OR \"qualitative\"[Title/Abstract] OR \"lived experience\"[Title/Abstract] OR \"patient-reported\"[Title/Abstract] OR \"recovery\"[Title] OR \"caregiver*\"[Title/Abstract] OR \"employment\"[Title/Abstract] OR \"adherence\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "44", "new_vs_prior_sweep": [ "42902289", "42898962", "42285160" ], "pmids": [ "42902289", "42898962", "42878529", "42867464", "42863911", "42850786", "42847035", "42831501", "42830726", "42830594", "42819869", "42820579", "42793368", "42789592", "42775184", "42766403", "42756307", "42748866", "42747873", "42736445", "42729350", "42729250", "42727520", "42716056", "42711749", "42709031", "42702907", "42680118", "42678618", "42586082", "42576393", "42542118", "42492718", "42464929", "42443536", "42296714", "42285160", "42236526", "42113129", "42103240", "42054082", "41924987", "41854950", "41848268", "41690355", "41396193", "41131937" ] }, "redflags": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (toxicity[tiab] OR \"neuroleptic malignant\"[tiab] OR emergency[tiab] OR \"suicide attempt\"[tiab] OR psychosis[ti] OR withdrawal[tiab] OR discontinuation[tiab])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28toxicity%5Btiab%5D+OR+%22neuroleptic+malignant%22%5Btiab%5D+OR+emergency%5Btiab%5D+OR+%22suicide+attempt%22%5Btiab%5D+OR+psychosis%5Bti%5D+OR+withdrawal%5Btiab%5D+OR+discontinuation%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "30", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"toxicity\"[Title/Abstract] OR \"neuroleptic malignant\"[Title/Abstract] OR \"emergency\"[Title/Abstract] OR \"suicide attempt\"[Title/Abstract] OR \"psychosis\"[Title] OR \"withdrawal\"[Title/Abstract] OR \"discontinuation\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "28", "new_vs_prior_sweep": [ "42900862", "42883387" ], "pmids": [ "42900862", "42883387", "42850223", "42813142", "42793368", "42779463", "42775184", "42770514", "42766403", "42716056", "42711749", "42711066", "42708514", "42647834", "42569600", "42489486", "42361653", "42349060", "42308110", "42216627", "42190847", "42142757", "42135523", "42130270", "42113129", "42112712", "42019954", "42014469", "41621866", "40364549" ] }, "metaanalysis": { "query": "(\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (meta-analysis[pt] OR systematic review[pt] OR meta-analy*[ti] OR \"umbrella review\"[ti])", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28meta-analysis%5Bpt%5D+OR+systematic+review%5Bpt%5D+OR+meta-analy%2A%5Bti%5D+OR+%22umbrella+review%22%5Bti%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "29", "translation": "(\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"meta-analysis\"[Publication Type] OR \"systematic review\"[Publication Type] OR \"meta analy*\"[Title] OR \"umbrella review\"[Title]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "26", "new_vs_prior_sweep": [ "42902526", "42901238", "42897074" ], "pmids": [ "42902526", "42901238", "42897074", "42863801", "42863775", "42859432", "42850223", "42838231", "42832826", "42815730", "42815432", "42772525", "42765379", "42762641", "42758600", "42702273", "42687371", "42669383", "42541933", "42471042", "42350629", "42296714", "42233646", "42215638", "42168580", "42103244", "42014469", "41790247", "41558805" ] }, "catchall": { "query": "(\"bipolar disorder\"[mh] OR \"bipolar disorder\"[tiab] OR \"bipolar depression\"[tiab] OR mania[ti] OR lithium[ti]) NOT (battery OR electrode OR anode OR cathode OR TURP OR hemiarthroplasty)", "datetype": "pdat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+%22bipolar+disorder%22%5Btiab%5D+OR+%22bipolar+depression%22%5Btiab%5D+OR+mania%5Bti%5D+OR+lithium%5Bti%5D%29+NOT+%28battery+OR+electrode+OR+anode+OR+cathode+OR+TURP+OR+hemiarthroplasty%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "636", "translation": "((\"bipolar disorder\"[MeSH Terms] OR \"bipolar disorder\"[Title/Abstract] OR \"bipolar depression\"[Title/Abstract] OR \"mania\"[Title] OR \"lithium\"[Title]) NOT (\"batterie\"[All Fields] OR \"batteries\"[All Fields] OR \"battery\"[All Fields] OR \"battery s\"[All Fields] OR (\"electrode s\"[All Fields] OR \"electroded\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"electrode\"[All Fields] OR \"electrodic\"[All Fields]) OR (\"anodic\"[All Fields] OR \"anodically\"[All Fields] OR \"anodization\"[All Fields] OR \"anodize\"[All Fields] OR \"anodized\"[All Fields] OR \"anodizing\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"anode\"[All Fields] OR \"anodes\"[All Fields]) OR (\"cathode s\"[All Fields] OR \"cathodic\"[All Fields] OR \"cathodically\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"cathode\"[All Fields] OR \"cathodes\"[All Fields]) OR (\"transurethral resection of prostate\"[MeSH Terms] OR (\"transurethral\"[All Fields] AND \"resection\"[All Fields] AND \"prostate\"[All Fields]) OR \"transurethral resection of prostate\"[All Fields] OR \"turp\"[All Fields]) OR (\"hemiarthroplasty\"[MeSH Terms] OR \"hemiarthroplasty\"[All Fields] OR \"hemiarthroplasties\"[All Fields]))) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "prior_count": "596", "new_vs_prior_sweep": [ "42906709", "42906286", "42905247", "42904336", "42902526", "42902289", "42901911", "42901213", "42900862", "42900401", "42900133", "42900085", "42899847", "42898962", "42898785", "42898579", "42897416", "42897264", "42895747", "42895194", "42894926", "42894686", "42894408", "42892769", "42892098", "42891241", "42890089", "42889292", "42889102", "42888136", "42887787", "42887160", "42887149", "42883387", "42883304", "42882753", "42617977", "42285160", "42113112", "42083011" ], "pmids": [ "42906709", "42906286", "42905247", "42904336", "42902526", "42902289", "42901911", "42901213", "42900862", "42900401", "42900133", "42900085", "42899847", "42898962", "42898785", "42898579", "42897416", "42897264", "42895747", "42895194", "42894926", "42894686", "42894408", "42892769", "42892098", "42891241", "42890089", "42889292", "42889102", "42888136", "42887787", "42887160", "42887149", "42883387", "42883304", "42882753", "42880607", "42880378", "42879783", "42878529", "42878230", "42878052", "42878012", "42877034", "42876975", "42876217", "42875515", "42873245", "42872493", "42872469", "42872398", "42872157", "42871752", "42870751", "42869750", "42869174", "42869119", "42869034", "42868737", "42867914", "42867464", "42865474", "42865315", "42863935", "42863911", "42863801", "42863775", "42863721", "42863717", "42862947", "42862819", "42862625", "42861028", "42860592", "42859565", "42859432", "42858466", "42858455", "42857961", "42857933", "42857347", "42857214", "42856213", "42852912", "42851418", "42850786", "42850782", "42850618", "42850223", "42849899", "42849864", "42849015", "42848524", "42847926", "42847418", "42847035", "42846741", "42846150", "42844253", "42844245", "42842759", "42841250", "42840883", "42840796", "42839929", "42839686", "42839406", "42839301", "42838826", "42838231", "42838229", "42837343", "42836332", "42836128", "42835777", "42835728", "42835657", "42834515", "28520367", "42833865", "42833410", "42832826", "42832465", "42831873", "42831501", "42830726", "42830691", "42830608", "42830172", "42829941", "42829204", "42828221", "42827030", "42826920", "42826581", "42825604", "42825385", "42825101", "42823992", "42820099", "42819869", "42822715", "42822212", "42821910", "42821908", "42820579", "42819357", "42818443", "42818201", "42818084", "42818077", "42817737", "42816601", "42816538", "42815890", "42815732", "42815731", "42815730", "42815432", "42815348", "42815091", "42814580", "42813743", "42813637", "42813417", "42813267", "42813142", "42813121", "42812927", "42812653", "42811265", "42811160", "42810282", "42809830", "42808681", "42808360", "42806848", "42806117", "42805590", "42805036", "42803750", "42803710", "42803524", "42803517", "42803346", "42803313", "42802085", "42800802", "42800178", "42799904", "42799487", "42799444", "42799438", "42799183", "42797751", "42797527", "42797424", "42797042", "42796993", "42796038", "42794424", "42793759", "42793390", "42793368", "42793041", "42790389", "42790157", "42789617", "42789592", "42789145", "42786849", "42786613", "42786409", "42786255", "42786204", "42785390", "42783804", "42782583", "42782354", "42780875", "42780312", "42779463", "42778699", "42777340", "42776273", "42775117", "42774256", "42773517", "42772525", "42772133", "42771937", "42771910", "42771845", "42770514", "42770460", "42769974", "42769575", "42768410", "42768304", "42768146", "42768143", "42768137", "42767564", "42767304", "42767042", "42766483", "42766403", "42765980", "42765891", "42765379", "42765378", "42765131", "42764573", "42764057", "42762875", "42762641", "42760730", "42759730", "42758600", "42758340", "42758023", "42757275", "42756307", "42756115", "42755423", "42754946", "42754622", "42754432", "42753132", "42753068", "42752982", "42752511", "42752499", "42751051", "42750943", "42750579", "42750440", "42750371", "42749778", "42749683", "42749160", "42748866", "42747910", "42747873", "42747853", "42747205", "42745834", "42744699", "42743756", "42743600", "42743494", "42742966", "42742582", "42738216", "42738093", "42737920", "42736445", "42736349", "42735779", "42735776", "42734386", "42734074", "30855854", "42731353", "42731340", "42729831", "42729405", "42729250", "42728701", "42727520", "42727204", "42725756", "42723029", "42721947", "42721927", "42721208", "42721112", "42719610", "42719005", "42717300", "42717077", "42716347", "42716345", "42716328", "42716056", "42715860", "42714275", "42713675", "42711749", "32644424", "42711066", "42710238", "42709031", "42708514", "42706644", "42705446", "42704652", "42703744", "42702907", "42702788", "42702273", "42700777", "42700485", "42698177", "42697570", "42696542", "42693835", "42693365", "42692849", "42692293", "42691792", "42690246", "42690023", "42689690", "42688822", "42688558", "42688390", "42687371", "42686314", "42686073", "42684694", "42684674", "42683441", "42680959", "42680118", "42680113", "42677959", "42677899", "42677074", "42676950", "42676571", "42676118", "42675803", "42675562", "42675468", "42674302", "42673769", "42670596", "42670435", "42670081", "42669965", "42669399", "42669383", "42668499", "42666967", "42663665", "42659872", "42657654", "42657624", "42649425", "42647834", "42642929", "42640795", "42640790", "42633551", "42628206", "42625058", "42620963", "42617977", "42617562", "42611127", "42608581", "42602849", "42600836", "42598032", "42593346", "42593062", "42592752", "42587157", "42586174", "42586082", "42586081", "42578824", "42578538", "42576393", "42571148", "42570504", "42570035", "42569600", "42569312", "42568249", "42551595", "42549780", "42546815", "42542170", "42542119", "42542118", "42541933", "42537296", "42533130", "42532680", "42530412", "42528360", "42528353", "42526346", "42521114", "42508239", "42503444", "42502622", "42498564", "42498428", "42496811", "42492718", "42492238", "42489486", "42485973", "42484424", "42482531", "42481733", "42478737", "42473997", "42473346", "42471042", "42465921", "42464929", "42462416", "42458001", "42454604", "42443536", "42442754", "42434329", "42431030", "42425479", "42425276", "42425032", "42424705", "42418908", "42418870", "42407271", "42399489", "42399185", "42398295", "42392965", "42391980", "42387309", "42385293", "42379930", "42377482", "42372694", "42372341", "42366285", "42364336", "42364322", "42364174", "42362820", "42361653", "42350629", "42349060", "42341384", "42341357", "42337416", "42335719", "42330862", "42324672", "42323516", "42320288", "42320287", "42320286", "42319208", "42315454", "42315403", "42314953", "42314447", "42308110", "42307011", "42306998", "42302379", "42296714", "42285160", "42269287", "42268602", "42268594", "42267832", "42263791", "42261659", "42247738", "42242171", "42236526", "42233646", "42217402", "42216627", "42215638", "42203964", "42203049", "42190891", "42190889", "42190847", "42189148", "42184576", "42173374", "42173043", "42168580", "42167693", "42166925", "42165752", "42162625", "42142757", "42142752", "42142751", "42142749", "42135523", "42134763", "42134743", "42134004", "42130270", "42130202", "42125886", "42113129", "42113112", "42112712", "42107657", "42106928", "42106199", "42105579", "42103244", "42103240", "42100925", "42096890", "42095851", "42095358", "42092401", "42090938", "42087328", "42085651", "42083011", "42070700", "42069105", "42066850", "42060190", "42059153", "42055900", "42055136", "42055134", "42054082", "42053350", "42050794", "42047661", "42047475", "42035800", "42035591", "42034248", "42020718", "42019954", "42014469", "42013686", "41996964", "41972283", "41964330", "41955765", "41947665", "41935922", "41933711", "41924987", "41920509", "41904070", "41903946", "41863323", "41854950", "41848268", "41820247", "41814584", "41790247", "41789712", "41785480", "41785475", "41758223", "41755539", "41690355", "41670680", "41622888", "41621866", "41621592", "41558805", "41534638", "41521434", "41448348", "41421869", "41396193", "41352431", "41351381", "41275966", "41131937", "41109839", "41084836", "40875158", "40694402", "40364549", "40204235", "39961034", "39866640", "39786681", "39564233", "39307943", "39248202", "39233435", "39215619" ] }, "entry_date_catchall": { "query": "(\"bipolar disorder\"[mh] OR \"bipolar disorder\"[tiab] OR \"bipolar depression\"[tiab] OR mania[ti] OR lithium[ti]) NOT (battery OR electrode OR anode OR cathode OR TURP OR hemiarthroplasty)", "datetype": "edat", "date_from": "2026-08-28", "date_to": "2026-10-23", "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+%22bipolar+disorder%22%5Btiab%5D+OR+%22bipolar+depression%22%5Btiab%5D+OR+mania%5Bti%5D+OR+lithium%5Bti%5D%29+NOT+%28battery+OR+electrode+OR+anode+OR+cathode+OR+TURP+OR+hemiarthroplasty%29&retmode=json&retmax=10000&datetype=edat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23", "count": "479", "translation": "((\"bipolar disorder\"[MeSH Terms] OR \"bipolar disorder\"[Title/Abstract] OR \"bipolar depression\"[Title/Abstract] OR \"mania\"[Title] OR \"lithium\"[Title]) NOT (\"batterie\"[All Fields] OR \"batteries\"[All Fields] OR \"battery\"[All Fields] OR \"battery s\"[All Fields] OR (\"electrode s\"[All Fields] OR \"electroded\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"electrode\"[All Fields] OR \"electrodic\"[All Fields]) OR (\"anodic\"[All Fields] OR \"anodically\"[All Fields] OR \"anodization\"[All Fields] OR \"anodize\"[All Fields] OR \"anodized\"[All Fields] OR \"anodizing\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"anode\"[All Fields] OR \"anodes\"[All Fields]) OR (\"cathode s\"[All Fields] OR \"cathodic\"[All Fields] OR \"cathodically\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"cathode\"[All Fields] OR \"cathodes\"[All Fields]) OR (\"transurethral resection of prostate\"[MeSH Terms] OR (\"transurethral\"[All Fields] AND \"resection\"[All Fields] AND \"prostate\"[All Fields]) OR \"transurethral resection of prostate\"[All Fields] OR \"turp\"[All Fields]) OR (\"hemiarthroplasty\"[MeSH Terms] OR \"hemiarthroplasty\"[All Fields] OR \"hemiarthroplasties\"[All Fields]))) AND 2026/08/28:2026/10/23[Date - Entry]", "error": null, "prior_count": "438", "new_vs_prior_sweep": [ "42906901", "42906709", "42906286", "42905247", "42904336", "42902526", "42902289", "42901911", "42901213", "42900862", "42900401", "42900133", "42900085", "42899847", "42898962", "42898785", "42898579", "42897866", "42897416", "42897264", "42897150", "42895747", "42895194", "42894926", "42894686", "42894408", "42893365", "42892769", "42892098", "42891241", "42890725", "42890089", "42889292", "42889102", "42888136", "42887787", "42887160", "42887149", "42883387", "42883304", "42882753" ], "pmids": [ "42906901", "42906709", "42906286", "42905247", "42904336", "42902526", "42902289", "42901911", "42901213", "42900862", "42900401", "42900133", "42900085", "42899847", "42898962", "42898785", "42898579", "42897866", "42897416", "42897264", "42897150", "42895747", "42895194", "42894926", "42894686", "42894408", "42893365", "42892769", "42892098", "42891241", "42890725", "42890089", "42889292", "42889102", "42888136", "42887787", "42887160", "42887149", "42883387", "42883304", "42882753", "42880607", "42880378", "42879783", "42878529", "42878325", "42878230", "42878052", "42878012", "42877034", "42876975", "42876217", "42875515", "42875143", "42873245", "42872493", "42872469", "42872398", "42872157", "42871752", "42870751", "42870233", "42869750", "42869174", "42869119", "42869034", "42868737", "42868432", "42868396", "42868365", "42867914", "42867464", "42867166", "42865474", "42865315", "42864636", "42863935", "42863911", "42863801", "42863775", "42863721", "42863717", "42862947", "42862819", "42862625", "42861028", "42860592", "42859565", "42859432", "42858466", "42858455", "42857961", "42857933", "42857347", "42857214", "42856213", "42853004", "42852912", "42851418", "42850786", "42850782", "42850618", "42850223", "42849899", "42849864", "42849015", "42848524", "42847926", "42847418", "42847035", "42846741", "42846207", "42846150", "42846050", "42845909", "42845835", "42845822", "42845664", "42844259", "42844253", "42844245", "42843954", "42842759", "42841250", "42840883", "42840796", "42839958", "42839929", "42839686", "42839406", "42839301", "42838826", "42838231", "42838229", "42837343", "42836332", "42836128", "42835777", "42835728", "42835657", "42834515", "28520367", "42833865", "42833410", "42832826", "42832465", "42831873", "42831501", "42830726", "42830691", "42830608", "42830172", "42829941", "42829204", "42828221", "42828206", "42827030", "42826920", "42826581", "42825604", "42825385", "42825101", "42823992", "42820099", "42819869", "42822715", "42822212", "42821910", "42821908", "42820579", "42820261", "42819357", "42818443", "42818201", "42818084", "42818077", "42817910", "42817737", "42817231", "42816601", "42816538", "42815890", "42815732", "42815731", "42815730", "42815432", "42815348", "42815091", "42814580", "42813743", "42813637", "42813568", "42813562", "42813417", "42813267", "42813142", "42813121", "42812927", "42812653", "42811911", "42811265", "42811160", "42810282", "42809830", "42808681", "42808360", "42807048", "42806848", "42806117", "42805590", "42805036", "42803750", "42803710", "42803597", "42803524", "42803517", "42803346", "42803313", "42802085", "42800802", "42800178", "42799904", "42799487", "42799444", "42799438", "42799183", "42797751", "42797527", "42797424", "42797042", "42796993", "42796233", "42796038", "42794424", "42793759", "42793390", "42793368", "42793041", "42790389", "42790157", "42789617", "42789592", "42789145", "42786849", "42786613", "42786409", "42786255", "42786204", "42785390", "42783804", "42782583", "42782354", "42780875", "42780312", "42779463", "42778699", "42778562", "42777340", "42776273", "42775117", "42775051", "42774256", "42773517", "42772525", "42772133", "42771937", "42771910", "42771845", "42771435", "42771401", "42770514", "42770460", "42769974", "42769575", "42768882", "42768410", "42768304", "42768146", "42768143", "42768137", "42767564", "42767304", "42767042", "42766483", "42766403", "42765980", "42765891", "42765467", "42765449", "42765379", "42765378", "42765131", "42764573", "42764333", "42764057", "42763300", "42762875", "42762641", "42760730", "42759730", "42758600", "42758340", "42758023", "42757275", "42756307", "42756115", "42755433", "42755423", "42754946", "42754622", "42754565", "42754432", "42753132", "42753068", "42752982", "42752511", "42752499", "42751051", "42750943", "42750723", "42750579", "42750440", "42750371", "42749778", "42749683", "42749160", "42748866", "42747910", "42747873", "42747853", "42747205", "42746014", "42745834", "42744699", "42743756", "42743600", "42743494", "42742966", "42742582", "42740717", "42739546", "42738216", "42738093", "42737920", "42736445", "42736349", "42736293", "42735779", "42735776", "42735124", "42734386", "42734074", "30855854", "42731353", "42731340", "42729831", "42729405", "42729250", "42728961", "42728701", "42727520", "42727204", "42725756", "42724943", "42724875", "42723973", "42723773", "42723029", "42721947", "42721927", "42721208", "42721112", "42719610", "42719198", "42719064", "42719005", "42717300", "42717077", "42716347", "42716345", "42716328", "42716056", "42715860", "42714275", "42713736", "42713711", "42713675", "42712571", "42711749", "32644424", "42711066", "42710238", "42709031", "42708514", "42706644", "42705446", "42704652", "42703744", "42703083", "42702907", "42702788", "42702273", "42700777", "42700489", "42700485", "42700484", "42698604", "42698177", "42698086", "42697570", "42696542", "42695067", "42694864", "42694849", "42694435", "42694386", "42693835", "42693365", "42692849", "42692293", "42691792", "42690246", "42690023", "42689690", "42688839", "42688822", "42688558", "42688390", "42688279", "42687878", "42687871", "42687371", "42686314", "42686073", "42684694", "42684674", "42683441", "42680959", "42680118", "42680113", "42679550", "42677959", "42677899", "42677074", "42676950", "42676571", "42676118", "42675803", "42675562", "42675468", "42675160", "42674302", "42673908", "42673769", "42671279", "42671052", "42670909", "42670596", "42670435", "42670343", "42670081", "42669965", "42669399", "42669383", "42668911", "42668519", "42668499", "42666967", "42664567", "42664112", "42663665", "42661765", "42661060", "42661059", "42661025", "42660051", "42659872", "42659752", "42659751" ] } }, "pubmed_incremental_edat": { "query": "(\"bipolar disorder\"[mh] OR \"bipolar disorder\"[tiab] OR \"bipolar depression\"[tiab] OR mania[ti] OR lithium[ti]) NOT (battery OR electrode OR anode OR cathode OR TURP OR hemiarthroplasty)", "count": "34", "translation": "((\"bipolar disorder\"[MeSH Terms] OR \"bipolar disorder\"[Title/Abstract] OR \"bipolar depression\"[Title/Abstract] OR \"mania\"[Title] OR \"lithium\"[Title]) NOT (\"batterie\"[All Fields] OR \"batteries\"[All Fields] OR \"battery\"[All Fields] OR \"battery s\"[All Fields] OR (\"electrode s\"[All Fields] OR \"electroded\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"electrode\"[All Fields] OR \"electrodic\"[All Fields]) OR (\"anodic\"[All Fields] OR \"anodically\"[All Fields] OR \"anodization\"[All Fields] OR \"anodize\"[All Fields] OR \"anodized\"[All Fields] OR \"anodizing\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"anode\"[All Fields] OR \"anodes\"[All Fields]) OR (\"cathode s\"[All Fields] OR \"cathodic\"[All Fields] OR \"cathodically\"[All Fields] OR \"electrodes\"[MeSH Terms] OR \"electrodes\"[All Fields] OR \"cathode\"[All Fields] OR \"cathodes\"[All Fields]) OR (\"transurethral resection of prostate\"[MeSH Terms] OR (\"transurethral\"[All Fields] AND \"resection\"[All Fields] AND \"prostate\"[All Fields]) OR \"transurethral resection of prostate\"[All Fields] OR \"turp\"[All Fields]) OR (\"hemiarthroplasty\"[MeSH Terms] OR \"hemiarthroplasty\"[All Fields] OR \"hemiarthroplasties\"[All Fields]))) AND 2026/10/17:2026/10/23[Date - Entry]", "pmids": [ "42906901", "42906709", "42906286", "42905247", "42904336", "42902526", "42902289", "42901911", "42901213", "42900862", "42900401", "42900133", "42900085", "42899847", "42898962", "42898785", "42898579", "42897866", "42897416", "42897264", "42897150", "42895747", "42895194", "42894926", "42894686", "42894408", "42893365", "42892769", "42892098", "42891241", "42890725", "42890089", "42889292", "42889102" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22bipolar+disorder%22%5Bmh%5D+OR+%22bipolar+disorder%22%5Btiab%5D+OR+%22bipolar+depression%22%5Btiab%5D+OR+mania%5Bti%5D+OR+lithium%5Bti%5D%29+NOT+%28battery+OR+electrode+OR+anode+OR+cathode+OR+TURP+OR+hemiarthroplasty%29&retmode=json&retmax=10000&datetype=edat&mindate=2026%2F10%2F17&maxdate=2026%2F10%2F23", "error": null }, "followup_searches": { "liao_preprint_title": { "query": "\"Rare coding variation implicates thirteen genes in bipolar disorder\"[Title]", "count": "0", "translation": "\"Rare coding variation implicates thirteen genes in bipolar disorder\"[Title] AND 2020/01/01:2026/10/23[pdat]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Rare+coding+variation+implicates+thirteen+genes+in+bipolar+disorder%22%5BTitle%5D&retmode=json&retmax=10000&datetype=pdat&mindate=2020%2F01%2F01&maxdate=2026%2F10%2F23" }, "heart_failure_bipolar": { "query": "(\"heart failure\"[ti] AND (bipolar[tiab] OR mania[tiab])) AND (meta-analysis[pt] OR systematic review[pt] OR cohort[tiab])", "count": "0", "translation": "\"heart failure\"[Title] AND (\"bipolar\"[Title/Abstract] OR \"mania\"[Title/Abstract]) AND (\"meta-analysis\"[Publication Type] OR \"systematic review\"[Publication Type] OR \"cohort\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22heart+failure%22%5Bti%5D+AND+%28bipolar%5Btiab%5D+OR+mania%5Btiab%5D%29%29+AND+%28meta-analysis%5Bpt%5D+OR+systematic+review%5Bpt%5D+OR+cohort%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "erg_bipolar": { "query": "(electroretinogra*[tiab] OR ERG[ti]) AND (bipolar[tiab])", "count": "8", "translation": "(\"electroretinogra*\"[Title/Abstract] OR \"ERG\"[Title]) AND \"bipolar\"[Title/Abstract] AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [ "42820800", "42749176", "42669383", "42636766", "42485567", "42397659", "42365435", "41483445" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28electroretinogra%2A%5Btiab%5D+OR+ERG%5Bti%5D%29+AND+%28bipolar%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "isbd_consensus_2025_2026": { "query": "(ISBD[tiab] OR \"International Society for Bipolar Disorders\"[tiab]) AND (consensus[ti] OR task force[ti] OR recommendation*[ti] OR guideline*[ti])", "count": "14", "translation": "(\"ISBD\"[Title/Abstract] OR \"International Society for Bipolar Disorders\"[Title/Abstract]) AND (\"consensus\"[Title] OR \"task force\"[Title] OR \"recommendation*\"[Title] OR \"guideline*\"[Title]) AND 2025/01/01:2026/10/23[Date - Publication]", "error": null, "pmids": [ "42545207", "42489486", "42478728", "42460615", "42429210", "42310905", "42274191", "42249599", "41703784", "41083219", "40808269", "40705857", "40585074", "40411321" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28ISBD%5Btiab%5D+OR+%22International+Society+for+Bipolar+Disorders%22%5Btiab%5D%29+AND+%28consensus%5Bti%5D+OR+task+force%5Bti%5D+OR+recommendation%2A%5Bti%5D+OR+guideline%2A%5Bti%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2025%2F01%2F01&maxdate=2026%2F10%2F23" }, "gbd_bipolar": { "query": "(\"global burden\"[tiab] OR \"GBD\"[ti]) AND (bipolar[ti])", "count": "12", "translation": "(\"global burden\"[Title/Abstract] OR \"GBD\"[Title]) AND \"bipolar\"[Title] AND 2025/01/01:2026/10/23[Date - Publication]", "error": null, "pmids": [ "42688390", "42404031", "42335719", "41765205", "41626718", "41256940", "41110665", "41072877", "40580313", "40499832", "40245668", "39843750" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22global+burden%22%5Btiab%5D+OR+%22GBD%22%5Bti%5D%29+AND+%28bipolar%5Bti%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2025%2F01%2F01&maxdate=2026%2F10%2F23" }, "cochrane_bipolar_title_2026": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (bipolar[ti] OR mania[ti] OR lithium[ti])", "count": "1", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"bipolar\"[Title] OR \"mania\"[Title] OR \"lithium\"[Title]) AND 2026/01/01:2026/10/23[Date - Publication]", "error": null, "pmids": [ "41574662" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+lithium%5Bti%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F01%2F01&maxdate=2026%2F10%2F23" }, "wu_cnv_replication": { "query": "(\"copy number\"[tiab] OR CNV[tiab]) AND (bipolar[ti]) AND (Han[tiab] OR Chinese[tiab] OR replicat*[tiab])", "count": "1", "translation": "(\"copy number\"[Title/Abstract] OR \"CNV\"[Title/Abstract]) AND \"bipolar\"[Title] AND (\"Han\"[Title/Abstract] OR \"Chinese\"[Title/Abstract] OR \"replicat*\"[Title/Abstract]) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [ "42880378" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%28%22copy+number%22%5Btiab%5D+OR+CNV%5Btiab%5D%29+AND+%28bipolar%5Bti%5D%29+AND+%28Han%5Btiab%5D+OR+Chinese%5Btiab%5D+OR+replicat%2A%5Btiab%5D%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "shi_concern": { "query": "39549887[pmid]", "count": "1", "translation": "39549887[UID] AND 2000/01/01:2026/10/23[Date - Publication]", "error": null, "pmids": [ "39549887" ], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=39549887%5Bpmid%5D&retmode=json&retmax=10000&datetype=pdat&mindate=2000%2F01%2F01&maxdate=2026%2F10%2F23" } }, "cochrane_via_pubmed": { "diagnosis": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (diagnos*[ti] OR misdiagnos*[tiab] OR screening[ti] OR spectrum[ti] OR \"mixed features\"[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"diagnos*\"[Title] OR \"misdiagnos*\"[Title/Abstract] OR \"screening\"[Title] OR \"spectrum\"[Title] OR \"mixed features\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28diagnos%2A%5Bti%5D+OR+misdiagnos%2A%5Btiab%5D+OR+screening%5Bti%5D+OR+spectrum%5Bti%5D+OR+%22mixed+features%22%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "epidemiology": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (prevalence[tiab] OR incidence[tiab] OR cohort[ti] OR registry[tiab] OR \"global burden\"[tiab] OR course[ti]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"prevalence\"[Title/Abstract] OR \"incidence\"[Title/Abstract] OR \"cohort\"[Title] OR \"registry\"[Title/Abstract] OR \"global burden\"[Title/Abstract] OR \"course\"[Title])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28prevalence%5Btiab%5D+OR+incidence%5Btiab%5D+OR+cohort%5Bti%5D+OR+registry%5Btiab%5D+OR+%22global+burden%22%5Btiab%5D+OR+course%5Bti%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "genetics": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (genetic*[ti] OR GWAS[tiab] OR genome-wide[tiab] OR polygenic[tiab] OR \"copy number\"[tiab] OR heritab*[tiab] OR Mendelian[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"genetic*\"[Title] OR \"GWAS\"[Title/Abstract] OR \"genome-wide\"[Title/Abstract] OR \"polygenic\"[Title/Abstract] OR \"copy number\"[Title/Abstract] OR \"heritab*\"[Title/Abstract] OR \"Mendelian\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28genetic%2A%5Bti%5D+OR+GWAS%5Btiab%5D+OR+genome-wide%5Btiab%5D+OR+polygenic%5Btiab%5D+OR+%22copy+number%22%5Btiab%5D+OR+heritab%2A%5Btiab%5D+OR+Mendelian%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "neurobiology": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (MRI[tiab] OR neuroimaging[tiab] OR circadian[tiab] OR mitochondri*[tiab] OR inflammat*[ti]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"MRI\"[Title/Abstract] OR \"neuroimaging\"[Title/Abstract] OR \"circadian\"[Title/Abstract] OR \"mitochondri*\"[Title/Abstract] OR \"inflammat*\"[Title])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28MRI%5Btiab%5D+OR+neuroimaging%5Btiab%5D+OR+circadian%5Btiab%5D+OR+mitochondri%2A%5Btiab%5D+OR+inflammat%2A%5Bti%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "mania": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((mania[tiab] OR manic[tiab] OR \"mixed episode\"[tiab] OR \"mixed features\"[tiab]) AND (\"bipolar disorder\"[mh] OR bipolar[tiab]) AND (treatment[tiab] OR trial[tiab] OR antipsychotic*[tiab] OR agitation[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"mania\"[Title/Abstract] OR \"manic\"[Title/Abstract] OR \"mixed episode\"[Title/Abstract] OR \"mixed features\"[Title/Abstract]) AND (\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title/Abstract]) AND (\"treatment\"[Title/Abstract] OR \"trial\"[Title/Abstract] OR \"antipsychotic*\"[Title/Abstract] OR \"agitation\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28mania%5Btiab%5D+OR+manic%5Btiab%5D+OR+%22mixed+episode%22%5Btiab%5D+OR+%22mixed+features%22%5Btiab%5D%29+AND+%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Btiab%5D%29+AND+%28treatment%5Btiab%5D+OR+trial%5Btiab%5D+OR+antipsychotic%2A%5Btiab%5D+OR+agitation%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "depression": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (\"bipolar depression\"[tiab] OR (\"bipolar disorder\"[mh] AND depress*[ti] AND (treatment OR trial OR efficacy)))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"bipolar depression\"[Title/Abstract] OR (\"bipolar disorder\"[MeSH Terms] AND \"depress*\"[Title] AND (\"therapeutics\"[MeSH Terms] OR \"therapeutics\"[All Fields] OR \"treatments\"[All Fields] OR \"therapy\"[MeSH Subheading] OR \"therapy\"[All Fields] OR \"treatment\"[All Fields] OR \"treatment s\"[All Fields] OR (\"clinical trials as topic\"[MeSH Terms] OR (\"clinical\"[All Fields] AND \"trials\"[All Fields] AND \"topic\"[All Fields]) OR \"clinical trials as topic\"[All Fields] OR \"trial\"[All Fields] OR \"trial s\"[All Fields] OR \"trialed\"[All Fields] OR \"trialing\"[All Fields] OR \"trials\"[All Fields]) OR (\"efficacies\"[All Fields] OR \"efficacious\"[All Fields] OR \"efficaciously\"[All Fields] OR \"efficaciousness\"[All Fields] OR \"efficacy\"[All Fields])))) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%22bipolar+depression%22%5Btiab%5D+OR+%28%22bipolar+disorder%22%5Bmh%5D+AND+depress%2A%5Bti%5D+AND+%28treatment+OR+trial+OR+efficacy%29%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "maintenance": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (maintenance[tiab] OR relapse[tiab] OR recurrence[tiab] OR \"long-acting injectable\"[tiab] OR lamotrigine[tiab] OR valproate[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"maintenance\"[Title/Abstract] OR \"relapse\"[Title/Abstract] OR \"recurrence\"[Title/Abstract] OR \"long-acting injectable\"[Title/Abstract] OR \"lamotrigine\"[Title/Abstract] OR \"valproate\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28maintenance%5Btiab%5D+OR+relapse%5Btiab%5D+OR+recurrence%5Btiab%5D+OR+%22long-acting+injectable%22%5Btiab%5D+OR+lamotrigine%5Btiab%5D+OR+valproate%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "lithium": { "query": "\"Cochrane Database Syst Rev\"[jour] AND (lithium[ti] AND (bipolar[tiab] OR mood[tiab] OR kidney[tiab] OR renal[tiab] OR thyroid[tiab] OR suicide[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND (\"lithium\"[Title] AND (\"bipolar\"[Title/Abstract] OR \"mood\"[Title/Abstract] OR \"kidney\"[Title/Abstract] OR \"renal\"[Title/Abstract] OR \"thyroid\"[Title/Abstract] OR \"suicide\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28lithium%5Bti%5D+AND+%28bipolar%5Btiab%5D+OR+mood%5Btiab%5D+OR+kidney%5Btiab%5D+OR+renal%5Btiab%5D+OR+thyroid%5Btiab%5D+OR+suicide%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "antidepressant": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (antidepressant*[tiab] OR \"treatment-emergent\"[tiab] OR switch[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"antidepressant*\"[Title/Abstract] OR \"treatment-emergent\"[Title/Abstract] OR \"switch\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28antidepressant%2A%5Btiab%5D+OR+%22treatment-emergent%22%5Btiab%5D+OR+switch%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "psychotherapy": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (psychotherap*[tiab] OR psychoeducation[tiab] OR cognitive[ti] OR \"family-focused\"[tiab] OR \"self-management\"[tiab] OR digital[tiab] OR smartphone[tiab] OR app[tiab] OR lifestyle[tiab] OR exercise[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"psychotherap*\"[Title/Abstract] OR \"psychoeducation\"[Title/Abstract] OR \"cognitive\"[Title] OR \"family-focused\"[Title/Abstract] OR \"self-management\"[Title/Abstract] OR \"digital\"[Title/Abstract] OR \"smartphone\"[Title/Abstract] OR \"app\"[Title/Abstract] OR \"lifestyle\"[Title/Abstract] OR \"exercise\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28psychotherap%2A%5Btiab%5D+OR+psychoeducation%5Btiab%5D+OR+cognitive%5Bti%5D+OR+%22family-focused%22%5Btiab%5D+OR+%22self-management%22%5Btiab%5D+OR+digital%5Btiab%5D+OR+smartphone%5Btiab%5D+OR+app%5Btiab%5D+OR+lifestyle%5Btiab%5D+OR+exercise%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "comorbidity": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (ADHD[tiab] OR \"substance use\"[tiab] OR alcohol[tiab] OR cannabis[tiab] OR anxiety[ti] OR borderline[tiab] OR comorbid*[tiab] OR \"differential diagnosis\"[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"ADHD\"[Title/Abstract] OR \"substance use\"[Title/Abstract] OR \"alcohol\"[Title/Abstract] OR \"cannabis\"[Title/Abstract] OR \"anxiety\"[Title] OR \"borderline\"[Title/Abstract] OR \"comorbid*\"[Title/Abstract] OR \"differential diagnosis\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28ADHD%5Btiab%5D+OR+%22substance+use%22%5Btiab%5D+OR+alcohol%5Btiab%5D+OR+cannabis%5Btiab%5D+OR+anxiety%5Bti%5D+OR+borderline%5Btiab%5D+OR+comorbid%2A%5Btiab%5D+OR+%22differential+diagnosis%22%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "mortality": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (suicid*[tiab] OR mortality[tiab] OR cardiovascular[tiab] OR metabolic[tiab] OR obesity[tiab] OR diabetes[tiab] OR \"life expectancy\"[tiab] OR dementia[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"suicid*\"[Title/Abstract] OR \"mortality\"[Title/Abstract] OR \"cardiovascular\"[Title/Abstract] OR \"metabolic\"[Title/Abstract] OR \"obesity\"[Title/Abstract] OR \"diabetes\"[Title/Abstract] OR \"life expectancy\"[Title/Abstract] OR \"dementia\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28suicid%2A%5Btiab%5D+OR+mortality%5Btiab%5D+OR+cardiovascular%5Btiab%5D+OR+metabolic%5Btiab%5D+OR+obesity%5Btiab%5D+OR+diabetes%5Btiab%5D+OR+%22life+expectancy%22%5Btiab%5D+OR+dementia%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "pregnancy": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (pregnan*[tiab] OR postpartum[tiab] OR perinatal[tiab] OR lactation[tiab] OR breastfeeding[tiab] OR teratogen*[tiab] OR menopaus*[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"pregnan*\"[Title/Abstract] OR \"postpartum\"[Title/Abstract] OR \"perinatal\"[Title/Abstract] OR \"lactation\"[Title/Abstract] OR \"breastfeeding\"[Title/Abstract] OR \"teratogen*\"[Title/Abstract] OR \"menopaus*\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28pregnan%2A%5Btiab%5D+OR+postpartum%5Btiab%5D+OR+perinatal%5Btiab%5D+OR+lactation%5Btiab%5D+OR+breastfeeding%5Btiab%5D+OR+teratogen%2A%5Btiab%5D+OR+menopaus%2A%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "guidelines": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (guideline*[ti] OR consensus[ti] OR recommendation*[ti] OR practice guideline[pt]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"guideline*\"[Title] OR \"consensus\"[Title] OR \"recommendation*\"[Title] OR \"practice guideline\"[Publication Type])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28guideline%2A%5Bti%5D+OR+consensus%5Bti%5D+OR+recommendation%2A%5Bti%5D+OR+practice+guideline%5Bpt%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "biomarkers": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (biomarker*[tiab] OR actigraph*[tiab] OR \"digital phenotyp*\"[tiab] OR \"machine learning\"[tiab] OR speech[tiab] OR wearable*[tiab] OR \"passive sensing\"[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"biomarker*\"[Title/Abstract] OR \"actigraph*\"[Title/Abstract] OR \"digital phenotyp*\"[Title/Abstract] OR \"machine learning\"[Title/Abstract] OR \"speech\"[Title/Abstract] OR \"wearable*\"[Title/Abstract] OR \"passive sensing\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=%22Cochrane+Database+Syst+Rev%22%5Bjour%5D+AND+%28%28%22bipolar+disorder%22%5Bmh%5D+OR+bipolar%5Bti%5D+OR+mania%5Bti%5D+OR+manic%5Bti%5D+OR+hypomani%2A%5Bti%5D+OR+cyclothym%2A%5Bti%5D%29+AND+%28biomarker%2A%5Btiab%5D+OR+actigraph%2A%5Btiab%5D+OR+%22digital+phenotyp%2A%22%5Btiab%5D+OR+%22machine+learning%22%5Btiab%5D+OR+speech%5Btiab%5D+OR+wearable%2A%5Btiab%5D+OR+%22passive+sensing%22%5Btiab%5D%29%29&retmode=json&retmax=10000&datetype=pdat&mindate=2026%2F08%2F28&maxdate=2026%2F10%2F23" }, "neuromod": { "query": "\"Cochrane Database Syst Rev\"[jour] AND ((\"bipolar disorder\"[mh] OR bipolar[ti] OR mania[ti] OR manic[ti] OR hypomani*[ti] OR cyclothym*[ti]) AND (ketamine[tiab] OR esketamine[tiab] OR \"electroconvulsive\"[tiab] OR TMS[tiab] OR \"transcranial\"[tiab] OR psilocybin[tiab] OR ketogenic[tiab]))", "count": "0", "translation": "\"Cochrane Database Syst Rev\"[Journal] AND ((\"bipolar disorder\"[MeSH Terms] OR \"bipolar\"[Title] OR \"mania\"[Title] OR \"manic\"[Title] OR \"hypomani*\"[Title] OR \"cyclothym*\"[Title]) AND (\"ketamine\"[Title/Abstract] OR \"esketamine\"[Title/Abstract] OR \"electroconvulsive\"[Title/Abstract] OR \"TMS\"[Title/Abstract] OR \"transcranial\"[Title/Abstract] OR \"psilocybin\"[Title/Abstract] OR \"ketogenic\"[Title/Abstract])) AND 2026/08/28:2026/10/23[Date - Publication]", "error": null, "pmids": [], "url": 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